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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
450 Results for "
TNF Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (450)
450 Results for "TNF Receptor" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
KAG-308 is a potent selective and orally active agonist of EP4 receptor (a prostaglandin E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-α production. KAG-308 shows a Ki and an EC50 of 2.57 nM and 17 nM for human EP4 receptor, respectively, more selective over EP1, EP2, EP3 and IP receptor .
3
3 Cited Publications
Research Areas:
RO5256390 is an orally effective trace amine associated receptor 1 (TAAR1) agonist. RO5256390 exhibits pro-cognitive and antidepressant-like properties in rodent and primate models, showing similar brain activation patterns to Olanzapine (HY-14541). RO5256390 blocks compulsive overeating behavior in rats. RO5256390 can inhibit ATP (HY-B2176)-induced TNF secretion in mouse bone marrow-derived macrophages .
2
2 Cited Publications
Cat. No.: HY-P70805
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF11B; Osteoprotegerin; Prev. OPG; Tumor Necrosis Factor Receptor Superfamily, Member 11b; OCIF; Tumor Necrosis Factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory Factor; PDB5; TNF Receptor Superfamily Member 11b; TR1
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P71017
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF11B; Osteoprotegerin; Prev. OPG; Tumor Necrosis Factor Receptor Superfamily, Member 11b; OCIF; Tumor Necrosis Factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory Factor; PDB5; TNF Receptor Superfamily Member 11b; TR1
Species:
Mouse
Source:
HEK293
2
Research Areas:
Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research .
2
Research Areas:
Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research .
2
2 Cited Publications
Synonyms: Naphthazoline nitrate
Research Areas:
Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research .
2
Target:
Research Areas:
2
Category:
Flavonoids Flavones Isatis tinctoria L. Phenols Polyphenols Cruciferae Extract Plants Disease Research Fields Cancer
Target:
2
2 Cited Publications
Target:
Free Radical Scavengers TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)
Research Areas:
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .
2
2 Cited Publications
Cat. No.: HY-P4744
CAS No.: 597562-32-8
2
2 Cited Publications
Cat. No.: HY-P4744A
1
1 Cited Publications
Target:
Histamine Receptor Macrophage migration inhibitory factor (MIF) VEGFR Akt Interleukin Related
Research Areas:
Carebastine is an Ebastine (HY-B0674) metabolite and H1-receptor antagonist. Carebastine inhibits VEGFR-2 and Akt phosphorylation. Carebastine exerts an anti-inflammatory effect by inhibiting MIF as well as TNF-α and IL-6 production. Carebastine shows anti-angiogenic activity
1
1 Cited Publications
Cat. No.: HY-P72025
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF1B; TNF-R2; Prev. TNFR2; Tumor Necrosis Factor Receptor Superfamily, Member 1B; TNFBR; Tumor Necrosis Factor Receptor Superfamily, Member 1b; P75; Tumor Necrosis Factor Binding Protein 2; TNF-R-II; Tumor Necrosis Factor Beta Receptor; TNF-R75; Solub
Species:
Human
Source:
HEK293
1
1 Cited Publications
Synonyms: R848-d5; S28463-d5
1
1 Cited Publications
Cat. No.: HY-W014049
CAS No.: 66036-77-9
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P7053
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF11B; Osteoprotegerin; Prev. OPG; Tumor Necrosis Factor Receptor Superfamily, Member 11b; OCIF; Tumor Necrosis Factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory Factor; PDB5; TNF Receptor Superfamily Member 11b; TR1
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P72434
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF12A; Tumor Necrosis Factor Receptor Superfamily Member 12A; TNF Receptor Superfamily Member 12A; FGF-Inducible 14; TweakR; Tweak-Receptor; FN14; Tumor Necrosis Factor Receptor Superfamily, Member 12A; CD266; Type I Transmembrane Protein Fn14; Fibrob
Species:
Human
Source:
HEK293
1
1 Cited Publications
Target:
Research Areas:
PK68 is a potent orally active and specifical type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis .
1
1 Cited Publications
Cat. No.: HY-P700432
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF11B; Osteoprotegerin; Prev. OPG; Tumor Necrosis Factor Receptor Superfamily, Member 11b; OCIF; Tumor Necrosis Factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory Factor; PDB5; TNF Receptor Superfamily Member 11b; TR1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
