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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2954 Results for "
D3
" in MedChemExpress (MCE) Product Catalog:
Products (2954)
2954 Results for "D3" in MCE Product Catalog:
3
3
3 Cited Publications
Cat. No.: HY-P70998
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2D3; Ubiquitin Conjugating Enzyme E2 D3; UbcH5C; Ubiquitin-Conjugating Enzyme E2D 3 (Homologous To Yeast UBC4/5); Ubiquitin-Conjugating Enzyme E2D 3 (UBC4/5 Homolog,Yeast); (E3-Independent) E2 Ubiquitin-Conjugating Enzyme D3; Ubiquitin-Conjugating Enzy
Species:
Human
Source:
E. coli
3
3
3 Cited Publications
Target:
Research Areas:
L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors [3].
3
3 Cited Publications
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Research Areas:
L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors [3].
3
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
Perphenazine is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine also binds to Alpha-1A adrenergic receptor. Perphenazine inhibits cancer cell proliferation, and induces apoptosis. Perphenazine can be used in the research of mental disease, cancer, inflammation [3] .
2
2 Cited Publications
Cat. No.: HY-12053AS
Purity: ≥98.0%
Synonyms: KW-2307-D3 ditartrate; Nor-5'-anhydrovinblastine-D3 ditartrate
2
2
2 Cited Publications
Cat. No.: HY-W010388S1
CAS No.: 143827-19-4
2
2
2 Cited Publications
Cat. No.: HY-N0650S8
CAS No.: 105591-10-4
Synonyms: (-)-Serine-d3; (S)-Serine-d3
2
2 Cited Publications
Synonyms: (Rac)-Aramisulpride hydrochloride; (Rac)-Esamisulpride hydrochloride; (Rac)-DAN 2163 hydrochloride
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Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
2
2
2 Cited Publications
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Research Areas:
GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites .
2
2 Cited Publications
Synonyms: (Rac)-Aramisulpride; (Rac)-Esamisulpride; DAN 2163
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Research Areas:
Amisulpride ((Rac)-Aramisulpride) is a racemic (50:50) mixture of the R-Amisulpride (HY-109167) and S-Amisulpride (HY-126068). Amisulpride is a dopamine D2/D3 receptor antagonist with Ki values of 2.8 and 3.2 nM for human dopamine b>D2 and b>D3, respectively. Amisulpride is a 5-HT7 receptor antagonist with a Ki of 44 nM. Amisulpride can be used in psychiatric research [3].
2
2 Cited Publications
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Research Areas:
L-741626 is a selective D2 dopamine receptor antagonist, with the Ki values of 2.4, 100 and 220 nM for human D2, D3 and D4 receptors respectively .
2
2 Cited Publications
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Research Areas:
ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons .
2
2 Cited Publications
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TEI-9647, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9647 inhibits bone resorption and HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9647 has the potential for suppressing the excessive bone resorption and osteoclast formation in Paget's disease [3].
2
2 Cited Publications
Cat. No.: HY-N7045
CAS No.: 142796-22-3
Category:
Cyamopsis tetragonoloba (L.) Taub. Plants Flavanonols Glycine soya Flavonoids Phenols Polyphenols Compositae Extract Disease Research Fields Cancer
Target:
2
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Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
