10862 Results for "

active oxygen method

" in MedChemExpress (MCE) Product Catalog:
Products (10862)

10862 Results for "active oxygen method" in MCE Product Catalog:

49
49 Cited Publications
Cat. No.: HY-165529
CAS No.: 59721-28-7
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Camostat is an orally active trypsin inhibitor. Camostat can reduce pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decrease the proliferation and activation of pancreatic stellate cells (PSCs) .
loading...
    loading...
49
49 Cited Publications
Cat. No.: HY-13512
CAS No.: 59721-29-8
Purity:  99.94%
Synonyms: Camostat mesilate; FOY305; FOY-S980
Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase .
loading...
    loading...
49
49 Cited Publications
Cat. No.: HY-13001
CAS No.: 950769-58-1
Purity:  99.08%
Synonyms: AC220
Target:  

FLT3 Apoptosis PDGFR c-Kit

Research Areas:  

Cancer

Quizartinib (AC220) is an orally active, potent and selective FLT3 inhibitor. Quizartinib inhibits kinase activity of mutant-FLT3, -PDGFRA and -KIT isoforms and inhibits autophosphorylation. Quizartinib inhibits cellular proliferation, induces apoptosis in cancer cells. Quizartinib can be used for the research of cancer .
loading...
    loading...
49
49 Cited Publications
Cat. No.: HY-14217
CAS No.: 1132827-21-4
Purity:  99.81%
Synonyms: AC220 dihydrochloride
Target:  

FLT3 Apoptosis PDGFR c-Kit

Research Areas:  

Cancer

Quizartinib (AC220) dihydrochloride is an orally active, potent and selective FLT3 inhibitor. Quizartinib dihydrochloride inhibits kinase activity of mutant-FLT3, -PDGFRA and -KIT isoforms and inhibits autophosphorylation. Quizartinib dihydrochloride inhibits cellular proliferation, induces apoptosis in cancer cells. Quizartinib dihydrochloride can be used for the research of cancer .
loading...
    loading...
48
48 Cited Publications
Cat. No.: HY-D0821
CAS No.: 146368-11-8
Synonyms: Sulfo-Cyanine5
Target:  

Fluorescent Dye

Research Areas:  

Cancer

CY5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
loading...
    loading...
48
48 Cited Publications
Cat. No.: HY-B0593
CAS No.: 72558-82-8
Synonyms: GR20263
Research Areas:  

Infection Cancer

Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
loading...
    loading...
48
48 Cited Publications
Cat. No.: HY-B0593A
CAS No.: 78439-06-2
Synonyms: GR20263 pentahydrate
Research Areas:  

Infection Cancer

Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-A0070
CAS No.: 55-06-1
Synonyms: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium
Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-A0070B
CAS No.: 345957-19-9
Synonyms: Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-B0726
CAS No.: 54-71-7
Pilocarpine Hydrochloride is an orally active, selective M3 muscarinic acetylcholine receptor agonist. Pilocarpine Hydrochloride can induce seizures and is used in research on conditions such as epilepsy, dry mouth (xerostomia), and elevated intraocular pressure .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-B0726A
CAS No.: 92-13-7
Target:  

mAChR

Research Areas:  

Neurological Disease Cancer

Pilocarpine is an orally active, selective M3 muscarinic acetylcholine receptor agonist. Pilocarpine can induce seizures. Pilocarpine is used in research on conditions such as epilepsy, dry mouth (xerostomia), and elevated intraocular pressure .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-B1006
CAS No.: 148-72-1
Pilocarpine nitrate is an orally active, selective M3 muscarinic acetylcholine receptor agonist. Pilocarpine nitrate can induce seizures and is used in research on conditions such as epilepsy, dry mouth (xerostomia), and elevated intraocular pressure .
loading...
    loading...
46
46 Cited Publications
Cat. No.: HY-A0070A
CAS No.: 6893-02-3
Synonyms: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with Kis of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR .
loading...
    loading...
44
44 Cited Publications
Cat. No.: HY-B0497
CAS No.: 50-65-7
Synonyms: BAY2353
Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
loading...
    loading...
43
43 Cited Publications
Cat. No.: HY-K1078

MCE One Step TUNEL Apoptosis Detection Kit (FITC) provides a rapid and convenient method to detect cell apoptosis. After staining cells with this kit, live cells have no fluorescence, apoptosis cells show green fluorescence.

loading...
    loading...
43
43 Cited Publications
Cat. No.: HY-110164
CAS No.: 1781835-20-8
Target:  

Adiponectin Receptor

Research Areas:  

Metabolic Disease

AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively.
loading...
    loading...
43
43 Cited Publications
Cat. No.: HY-15848
CAS No.: 924416-43-3
Purity:  99.88%
Target:  

Adiponectin Receptor

Research Areas:  

Metabolic Disease

AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.
loading...
    loading...
43
43 Cited Publications
Cat. No.: HY-N0431
CAS No.: 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
loading...
    loading...
42
42 Cited Publications
Cat. No.: HY-K0314

MCE ATP Assay Kit provides a rapid method to measure intracellular ATP. The kit is suitable for ATP determination in cells, tissue, and other biological samples.

loading...
    loading...
40
40 Cited Publications
Cat. No.: HY-118411
CAS No.: 61135-33-9
Purity:  99.78%
Synonyms: EdU
Target:  

PROTAC Linkers

Research Areas:  

Cancer

5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
loading...
    loading...