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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
Ang II
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "Ang II" in MCE Product Catalog:
258
258 Publications Verification
Synonyms: Angiotensin II; Ang II; DRVYIHPF
Target:
258
258 Publications Verification
Synonyms: Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate
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Áreas de investigación:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
258
258 Publications Verification
Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
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Áreas de investigación:
18
18 Cited Publications
Synonyms: TXA127; Angiotensin (1-7); Ang-(1-7)
18
18 Cited Publications
Synonyms: TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate
17
17 Cited Publications
Áreas de investigación:
YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors .
17
17 Cited Publications
Áreas de investigación:
YS-49 (monohydrate) is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors .
8
8 Cited Publications
Referencia número: HY-B0202
No. CAS: 138402-11-6
Synonyms: SR-47436; BMS-186295
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Áreas de investigación:
Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
7
Áreas de investigación:
Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Spironolactone is an aldosterone antagonist that acts on the aldosterone mineralocorticoid receptor (IC50=24 nM) and androgen receptor (IC50=77 nM), promotes podocyte autophagy and regulates pain. Spironolactone improves hypertension-related vascular hypertrophy and remodeling by reducing angiotensin II (Ang II)-induced inflammation, reduces aldosterone-induced vascular and soft tissue calcification through PIT1-dependent signaling, and alleviates vascular dysfunction in type II diabetic mice by reducing oxidative stress and restoring NO/GC signaling; at low concentrations, it and its metabolites can interfere with aldosterone biosynthesis in the adrenal cortex and inhibit voltage-dependent Ca 2+ channels to exert antihypertensive effects .
2
2 Cited Publications
Referencia número: HY-N0515
No. CAS: 945619-74-9
1
1 Cited Publications
Referencia número: HY-160187
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Áreas de investigación:
AAA is an orally active 20-HETE receptor antagonist. AAA exerts antihypertensive and organoprotective effects. AAA blocks 20-HETE prohypertensive actions, suppresses intrarenal and circulating angiotensin II levels, and interferes with renin-angiotensin system interactions. AAA attenuates development of, and reverses established, ANG II (HY-13948)-dependent malignant hypertension. AAA reduces albuminuria, glomerulosclerosis, and cardiac hypertrophy linked to malignant hypertension. AAA can be used for the research of malignant hypertension .
1
Referencia número: HY-P1236
No. CAS: 88898-17-3
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse)
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Áreas de investigación:
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Áreas de investigación:
Angiotensin-converting enzyme (Kininase II) is a dicarboxypeptidase, it converts inactive Angiotensin I (Ang I) to active Ang II and degrades active bradykinin (BK). Angiotensin-converting enzyme is a potent vasoconstrictor, is often used in biochemical studies .
Referencia número: HY-P1236A
Synonyms: Atrial natriuretic factor (1-28) (rat, mouse) TFA
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Áreas de investigación:
Referencia número: HY-13948F1
Pureza: 99.53%
Synonyms: Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled
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Áreas de investigación:
Synonyms: Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF
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Áreas de investigación:
Referencia número: HY-P3136
No. CAS: 25849-90-5
Synonyms: TRV120055
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Áreas de investigación:
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Áreas de investigación:
TK-129 is an orally active, low-toxicity, potent KDM5B inhibitor (with high affinity; IC50=44 nM). TK-129 exerts cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 reduces ang II-induced activation of cardiac fibroblasts in vitro and reduces isoprenaline-induced myocardial remodelling and fibrosis in vivo. TK-129 can be used in studies of cardiovascular disease .
Referencia número: HY-N7665
No. CAS: 99365-23-8
Category:
Triterpenes Umbelliferae Extract Terpenoids Metabolic Disease Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
