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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
APAP
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "APAP" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: APAP-Cys TFA
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Paracetamol-cysteine (TFA) is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005) .
Synonyms: APAP-glu
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Cat. No.: HY-N3431
CAS No.: 20196-89-8
Cat. No.: HY-170495
CAS No.: 3099659-64-7
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HDAC6 degrader-5 (Compound 6) exhibits inhibitory and degradation activity against HDAC6, with an IC50 of 4.95 nM and a DC50 of 0.96 nM. HDAC6 degrader-5 inhibits the release of TNF-α, IL-1β and IL-6, blocks the hepatocyte apoptosis. HDAC6 degrader-5 exhibits anti-inflammatory activity in mouse APAP (HY-66005)-induced liver injury models .
Cat. No.: HY-139093
CAS No.: 53446-10-9
Synonyms: APAP-Cys
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Cat. No.: HY-N7697C
CAS No.: 127171-88-4
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2,4'-Dihydroxybenzophenone ((Z)-SU4312) exhibited estrogenic activities. 2,4'-Dihydroxybenzophenone has oral bioactivity that can effectively protect C57BL/6J mice from Acetaminophen (HY-66005, APAP)-induced hepatotoxicity .
Cat. No.: HY-173564
CAS No.: 2758171-54-7
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DW34 is an orally active pan-BRD4-D1 biased inhibitor with additional BRD4-D2 inhibitive activity. DW34 displays comparable inhibitive efficacy to I-BET151 (HY-13235) (EC50 = 0.16 μM) with low nanomolar EC50 values of 0.14 μM. DW34 significantly reduces liver inflammation induced by LPS (HY-D1056) and APAP (HY-66005) via reducing chemokine expression and cellular necrosis .
Cat. No.: HY-N12706
CAS No.: 2763689-78-5
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Cat. No.: HY-113083R
CAS No.: 16110-10-4
Synonyms: APAP-glu (Standard)
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Cat. No.: HY-N11433
CAS No.: 1950581-97-1
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Cat. No.: HY-N12426
CAS No.: 2763686-96-8
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Cat. No.: HY-D3008
CAS No.: 3032633-52-3
Cat. No.: HY-N15535
CAS No.: 871720-22-8
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Cat. No.: HY-156431
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Anti-inflammatory agent 61 (Compound 5b) is a potent anti-inflammatory agent. Anti-inflammatory agent 61 reduces TNF-α expression in LPS-induced inflammation in RAW 264.7 cells. Anti-inflammatory agent 61 alleviates APAP-induced inflammation in HepG2 cells .
Cat. No.: HY-168327
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LH10 is a fexaramine-based agonist for FXR with an EC50 of 0.14 μM. LH10 exhibits liver protection efficacy, ameliorates the alpha naphthylisothiocyanate (ANIT)-induced cholestasis, APAP (HY-66005)-induced acute liver injury and non-alcoholic steatohepatitis (NASH) in mouse models .
Cat. No.: HY-113083A
Synonyms: APAP-glu potassium
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Acetaminophen glucuronide potassium (APAP-glu potassium) is the inactive glucuronide metabolite of Acetaminophen (HY-66005). Acetaminophen glucuronide potassium can be used as a biomarker to measure glucuronidation activity or hepatic drug metabolism capacity .
Cat. No.: HY-W725454
CAS No.: 118-57-0
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Acetaminosalol, a merged ester NSAID–APAP hybrid, is a metabolite of Benorylate (HY-107795) and a prodrug of Acetaminophen (HY-66005) and Aalicylic acid (HY-B0167). Acetaminosalol can be used for the research of acute rheumatism .
Cat. No.: HY-P74590
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RING1 and YY1-binding protein; APAP-1; RYBP; DEDAF; YEAF1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
