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Bb subunit

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Complement System (1) MHC (1)
By Research Areas:	Endocrinology (1) Inflammation/Immunology (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: SF3B1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991022

Ruxoprubart NM8074	Complement System	Endocrinology
Ruxoprubart (NM8074) is an inhibitor of complement factor B (Bb *subunit). Ruxoprubart selectively binds to active Bb to inhibit the alternative complement pathway without affecting the classical complement pathway. By blocking the activities of AP C3* and C5 convertases, Ruxoprubart effectively inhibits red blood cell hemolysis and reduces C3b deposition, thereby preventing intravascular and extravascular hemolysis. Ruxoprubart can be used in research related to paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, C3 glomerulopathy, and IgA nephropathy .

HY-P991787

Anti-HLA-A2 Antibody (BB7.2)	MHC	Inflammation/Immunology
Anti-HLA-A2 Antibody (BB7.2) reacts with the alpha subunit of the human leukocyte antigen-A2 (HLA-A2). Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991022

Ruxoprubart NM8074	Complement System	Endocrinology
Ruxoprubart (NM8074) is an inhibitor of complement factor B (Bb *subunit). Ruxoprubart selectively binds to active Bb to inhibit the alternative complement pathway without affecting the classical complement pathway. By blocking the activities of AP C3* and C5 convertases, Ruxoprubart effectively inhibits red blood cell hemolysis and reduces C3b deposition, thereby preventing intravascular and extravascular hemolysis. Ruxoprubart can be used in research related to paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, C3 glomerulopathy, and IgA nephropathy .

HY-P991787

Anti-HLA-A2 Antibody (BB7.2)	MHC	Inflammation/Immunology
Anti-HLA-A2 Antibody (BB7.2) reacts with the alpha subunit of the human leukocyte antigen-A2 (HLA-A2). Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .

Species:	Human (2) Rhesus Macaque (1) Bovine (1) Mouse (1) Cynomolgus (2)
Tag:	His (4) Tag Free (1) Fc (2)
Source:	HEK293 (2) P. pastoris (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73351

	PDGF-BB Protein, Human (P.pastoris, His) 1 Publications Verification Platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS	Human	P. pastoris
	The PDGF-BB protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. It is known for its potent mitogenic effects on mesenchymal cells and is essential for the normal proliferation and recruitment of pericytes and vascular smooth muscle cells in tissues such as the central nervous system, skin, lungs, heart, and placenta. PDGF-BB Protein, Human (P.pastoris, His) is the recombinant human-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

HY-P73352

	PDGF-BB Protein, Mouse (P.pastoris, His) Platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS	Mouse	P. pastoris
	PDGF-BB, a crucial growth factor, regulates diverse cellular processes, including development, proliferation, migration, survival, and chemotaxis. It is vital for tissue proliferation, blood vessel development, and kidney glomeruli formation. PDGF-BB interacts with PDGFRA, PDGFRB, XLKD1, LRP1, and SORL1, highlighting its versatile cellular involvement. PDGF-BB Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

HY-P73351Y

	PDGF-BB Protein, Human (P.pastoris, His, solution) Platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS	Human	P. pastoris
	The PDGF-BB protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. It is known for its potent mitogenic effects on mesenchymal cells and is essential for the normal proliferation and recruitment of pericytes and vascular smooth muscle cells in tissues such as the central nervous system, skin, lungs, heart, and placenta. PDGF-BB Protein, Human (P.pastoris, His) is the recombinant human-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

HY-P701237

	PDGF-BB Protein, Bovine (P. pastoris) PDGFB; PDGFB protein; Platelet derived growth factor subunit B	Bovine	P. pastoris
	PDGF-BB protein is an important member of the PDGF/VEGF growth factor family and plays a vital role in cell signaling and tissue development, contributing to cell growth, angiogenesis and blood vessel development. Its membership emphasizes the importance of fundamental physiological processes that coordinate tissue homeostasis. PDGF-BB Protein, Bovine (P. pastoris) is the recombinant bovine-derived PDGF-BB protein, expressed by P. pastoris , with tag free.

HY-P75966A

	PDGF-BB Protein, Cynomolgus (HEK293, mFc) Platelet-derived growth factor subunit B; PDGF-2; PDGFB	Cynomolgus	HEK293
	PDGF-BB is a growth factor frequently overexpressed in cancers, are novel potent lymphangiogenic factors. PDGF-BB Protein, Cynomolgus (HEK293, mFc) is the recombinant cynomolgus-derived PDGF-BB, expressed by HEK293, with N-mFc labeled tag.

HY-P75966

	PDGF-BB Protein, Cynomolgus (HEK293, mFc, solution) Platelet-derived growth factor subunit B; PDGF-2; PDGFB	Cynomolgus	HEK293
	PDGF-BB is a growth factor frequently overexpressed in cancers, are novel potent lymphangiogenic factors. PDGF-BB Protein, Cynomolgus (HEK293, mFc, solution) is the recombinant cynomolgus-derived PDGF-BB protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P74641

	PDGF-BB Protein, Rhesus Macaque (P.pastoris, His) Platelet-derived growth factor subunit B; PDGF-2; PDGFB	Rhesus Macaque	P. pastoris
	PDGF-BB Protein is a member of the PDGF family and promotes cell proliferation, survival, and migration by binding to the tyrosine kinase PDGF receptor. PDGF-BB Protein promotes tendon healing and neuroregulation after spinal cord hemisection in primates. PDGF-BB Protein, Rhesus Macaque (P.pastoris, His) is the recombinant Rhesus Macaque-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

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HY-P87014

	PPP3CB Antibody (YA6707) Calcineurin A beta antibody; Calcineurin A2 antibody; Calcineurin B, formerly antibody; Calmodulin dependent calcineurin A subunit beta isoform antibody; Calmodulin-dependent calcineurin A subunit beta isoform antibody; CALNA 2 antibody; CALNA2 antibody; CALNB antibody; CAM PRP catalytic subunit antibody; CAM-PRP catalytic subunit antibody; Calcineurin A beta antibody; Calcineurin A2 antibody; Calcineurin B, formerly antibody; Calmodulin dependent calcineurin A subunit beta isoform antibody; Calmodulin-dependent calcineurin A subunit beta isoform antibody; CALNA 2 antibody; CALNA2 antibody; CALNB antibody; CAM PRP catalytic subunit antibody; CAM-PRP catalytic subunit antibody; CNA2 antibody; CnAbeta antibody; PP2Bb_HUMAN antibody; PP2Bbeta antibody; PPP3CB antibody; Protein phosphatase 2B, catalytic subunit, beta isoform, formerly antibody; Protein phosphatase 3 (formerly 2B) catalytic subunit beta isoform antibody; Protein phosphatase 3 catalytic subunit beta isoform antibody; Protein phosphatase 3 catalytic subunit beta isozyme antibody; Serine/threonine protein phosphatase 2B catalytic subunit beta isoform antibody; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform antibody;	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	PPP3CB Antibody (YA6707) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPP3CB.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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