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Co2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (4) Amino Acid Decarboxylase (1) Antibiotic (1) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (25) c-Myc (1) Caspase (1) Drug Intermediate (2) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (6) Environmental Pollutants (3) Epigenetic Reader Domain (1) Fluorescent Dye (4) Fungal (1) GABA Receptor (2) Herbicide (3) iGluR (3) Insecticide (1) Isocitrate Dehydrogenase (IDH) (5) Isotope-Labeled Compounds (1) Lipase (1) Liposome (1) nAChR (2) Nucleoside Antimetabolite/Analog (1) Parasite (1) Photosystem II (1) PROTAC Linkers (12) PROTACs (1) Reference Standards (5) Small Interfering RNA (siRNA) (4)
By Research Areas:	Cancer (15) Infection (6) Metabolic Disease (20) Neurological Disease (4)
Click Chemistry:	ADC Synthesis (1) PROTAC Synthesis (6) Azide (7) Alkynes (2)
Oligonucleotides:	Pegylated Lipids (4) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Stearoyl-CoA Desaturase (SCD) Acetyl-CoA synthetase HMG-CoA Reductase (HMGCR) Malonyl-CoA Decarboxylase SARS-CoV Acetyl-CoA Carboxylase Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0227

THAM 1 Publications Verification Tris; Tris(hydroxymethyl)aminomethane	Biochemical Assay Reagents	Metabolic Disease
THAM (Tris) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications ^[2] .

HY-10932

Aniracetam 1 Publications Verification Ro 13-5057	nAChR iGluR	Neurological Disease
Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders ^[2] .

HY-P0294

Hexa-His 6X His Tag	Biochemical Assay Reagents	Others
Hexa-His (6X His Tag) is a commonly used affinity tag made up of six histidine residues. HEXA-HIS can bind to affinity chromatography media containing transition metal ions like nickel (Ni ²⁺) or cobalt (Co ²⁺), making it useful for protein purification ^[2].

HY-151644

Fluorescein hydrazide 1 Publications Verification	Fluorescent Dye	Others
Fluorescein hydrazide is a sensitive fluorescent probe for Hg ²⁺ and Co ²⁺ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM ^[1][2][3].

HY-126823

Phen Green SK diacetate (5/6-mixture) PGSK diacetate (5/6-mixture)	Fluorescent Dye	Others
Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe ²⁺, Cd ²⁺, Co ²⁺, Ni ²⁺, Zn ²⁺, etc. Phen green SK (PGSK) diacetate chelates Fe ²⁺, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively ^[2] .

HY-108369

Azido-PEG1-CH2CO2H	PROTAC Linkers	Cancer
Azido-PEG1-CH2CO2H is a PROTAC linker, which refers to the alkyl/ether composition .

HY-D0227J

THAM hydrochloride (≥99%, for cell culture) 1 Publications Verification Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)	Biochemical Assay Reagents	Metabolic Disease
THAM hydrochloride (≥99%, for cell culture) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM hydrochloride (≥99%, for cell culture) binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM hydrochloride (≥99%, for cell culture) may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM hydrochloride (≥99%, for cell culture) removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM hydrochloride (≥99%, for cell culture) can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM hydrochloride (≥99%, for cell culture) is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications ^[2] .

HY-W011060

Cryptand 2.2.2 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexaCosane	Biochemical Assay Reagents	Others
Cryptand 2.2.2 (4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane) is a metal ion chelator. Cryptand 2.2.2 forms stable mononuclear, protonated and dinuclear complexes with copper (II) ions; forms protonated complexes with hydrogen ions; and also forms stable complexes with Zn ²⁺, Co ²⁺, Ni ²⁺, Cd ²⁺, Hg ²⁺ and Pb ²⁺ ions. Cryptand 2.2.2 can be used for the preparation of nanoparticles, transition metal compounds, etc.

HY-Y1422I

Lipase,Pseudomonas fluorescens (Immobilized)	Environmental Pollutants Biochemical Assay Reagents Lipase	Others
Lipase, Pseudomonas fluorescens (Immobilized) is an immobilized biocatalyst derived from Pseudomonas fluorescens. Lipase, Pseudomonas fluorescens (Immobilized) efficiently catalyzes the hydrolysis, esterification and transesterification of triacylglycerols in solvent-free systems, and is particularly suitable for biodiesel production from soybean oil and selective modification of oils rich in EPA and DHA. Lipase, Pseudomonas fluorescens (Immobilized) exhibits optimal activity at pH 8.5 and 45°C, and retains residual activity after repeated cycles of use. Lipase, Pseudomonas fluorescens (Immobilized) is activated by Ca ²⁺, but inhibited by Co ²⁺, Ni ²⁺, Fe ³⁺, Fe ²⁺ and EDTA ^[2].

HY-164642

Ribulose 1,5-bisphosphate RuBP	Endogenous Metabolite	Metabolic Disease
Ribulose 1,5-bisphosphate (RUBP) is a vital photosynthetic intermediate and substrate. Ribulose 1,5-bisphosphate acts as both product and substrate for Thermococcus kodakarensis KOD1 R15Pi. Ribulose 1,5-bisphosphate tightly binds to inactive RuBP carboxylase sites in plant leaves.Ribulose 1,5-bisphosphate serves as the key substrate for CO₂ fixation in photosynthesis. Ribulose 1,5-bisphosphate supports carboxylation and regeneration processes in photosynthesis. Ribulose 1,5-bisphosphate determines the dynamic transition temperature of photosynthetic control. Ribulose 1,5-bisphosphate can be used for photosynthesis and enzyme mechanism research ^[2] .

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Environmental Pollutants Fluorescent Dye	Others
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release ^[2] .

HY-E70015

Phosphoenolpyruvate carboxylase, Microorganism PEPC	Others	Others
Phosphoenolpyruvate carboxylase, Microorganism (PEPC) is a carbon dioxide fixing enzyme that in an irreversible manner and in the presence of Mg ²⁺, converts phosphoenolpyruvate and bicarbonate into oxaloacetate and inorganic phosphorus. Phosphoenolpyruvate carboxylase catalyses the primary assimilation of CO(2) in Crassulacean acid metabolism plants. Phosphoenolpyruvate carboxylase plays a major role in setting the day-night pattern of metabolism in plants ^[2].

HY-118877

Urea-13C 1 Publications Verification Carbonyl diamide-¹³C	Isotope-Labeled Compounds	Infection
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

HY-P2796

Pyruvate decarboxylase PDC	Biochemical Assay Reagents	Metabolic Disease
Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO₂ .

HY-D2775

Cobalt(II) ions probe 1	Fluorescent Dye	Others
Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co ²⁺ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co ²⁺ in the presence of other metal ions (Ex: 380 nm) .

HY-116482

Desmedipham	Herbicide	Others
Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO₂ fixation and the production of intermediary energy components-ATP and NADPH₂ and inhibition of Hill reaction .

HY-122702

PEG6-(CH2CO2H)2	PROTAC Linkers	Others
PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation .

HY-131647

Pomalidomide 4'-PEG5-acid Pomalidomide-PEG5-Co2H	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology .

HY-W157376

PAMAM Dendrimer G0.0 amine (20% in methanol)	Bacterial Antibiotic Drug Intermediate	Infection Cancer
PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC₅₀ = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC₅₀ = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems ^[2] .

HY-W004297

1-Nonadecanol	Drug Intermediate	Others
1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO₂) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata ^[2].

HY-D0227B

THAM acetate 1 Publications Verification Tris acetate; Tris(hydroxymethyl)aminomethane acetate	Biochemical Assay Reagents	Metabolic Disease
THAM acetate is a low-toxicity amino alcohol buffer, a CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM acetate binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM acetate may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM acetate removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM acetate can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM acetate is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications ^[2] .

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Polyvinyl alCohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)	Biochemical Assay Reagents Fungal	Infection
PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections ^[2] .

HY-140766

Azido-PEG5-CH2CO2-NHS	PROTAC Linkers	Cancer
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-131203

PROTAC BRD4 Degrader-6	PROTACs Epigenetic Reader Domain Apoptosis c-Myc Caspase	Cancer
PROTAC BRD4 Degrader-6 (compound 32a) is a potent small-molecule BRD4PROTAC degrader with IC₅₀ value of 2.7 nM for BRD4 BD1. PROTAC BRD4 Degrader-6 potently degrades BRD4 protein and inhibits the expression of c-Myc. PROTAC BRD4 Degrader-6 inhibits the proliferation of pancreatic cancer cell line BxPC3 and induces apoptosis. PROTAC BRD4 Degrader-6 can be used for human pancreatic cancer research (Pink: Mivebresib (HY-100015); Black: linker, Azido-PEG1-CH2CO2H (HY-108369); Blue: Lenalidomide (HY-A0003)) .

HY-151824

Boc-L-Phe(4-NH-Poc)-OH	ADC Linker	Others
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported ^[2]. Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-117146

Indoxacarb (S)-DPX-JW062	Parasite	Infection
Indoxacarb ((S)-DPX-JW062) is an oxathiazole insecticide with activity against a wide range of insect pests. Indoxacarb is used in forest pest management to control insect pests, and its toxicity has significant effects on adult individuals of the predatory stink bug Podisus distinctus. Indoxacarb showed high toxicity to P. distinctus at a lethal concentration (LC50 = 2.62 g L-1). Indoxacarb treatment significantly reduced the survival rate of P. distinctus, with the survival rate of individuals exposed to 2.62 g L-1 decreasing to 40.7%. Indoxacarb also reduced the respiration rate of P. distinctus from 18.45 to 14.41 μL CO2 h-1, and inhibited its food intake. P. distinctus showed hyperexcitatory responses after Indoxacarb treatment .

HY-W007431

Methyl 3,4-diaminobenzoate	Biochemical Assay Reagents	Others
Methyl 3,4-diaminobenzoate is an analogue of 3,4-diaminobenzoic acid, which contains the CO2H group protected as a methyl ester and the amino (NH2) substituents required to form the quinoxaline .

HY-W011816

1,2-Hexadecanediol	Biochemical Assay Reagents	Others
1,2-Hexadecanediol is a reducing agent. 1,2-Hexadecanediol facilitates the decomposition of the metal-organic precursor, forms an intermediate Co ²⁺Fe ³⁺-oleate complex .

HY-N3887

Evoxine Haplophytin B; Haplophytine B	Bacterial	Infection
Evoxine (Haplophytin B) is a compound that selectively inhibits CO2-induced immunosuppression and has activity in inhibiting the expression of interleukin-6 and chemokine CCL2 in human THP-1 macrophages. Evoxine shows antimicrobial activity against a wide range of bacteria, especially performing well in minimum inhibitory concentration (MIC) tests against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Evoxine extracts may find application in crude drug preparations in West Africa, provided that their in vivo toxicity results are negative .

HY-RS08758

*MT-CO2* Human Pre-designed siRNA Set A**	Small Interfering RNA (siRNA)	Others
MT-CO2 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-CO2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MT-CO2 Human Pre-designed siRNA Set A MT-CO2 Human Pre-designed siRNA Set A

HY-10932R

Aniracetam (Standard) Ro 13-5057 (Standard)	Reference Standards nAChR iGluR	Neurological Disease
Aniracetam (Standard) is the analytical standard of Aniracetam. This product is intended for research and analytical applications. Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO₂-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders ^[2] .

HY-151837

H-L-Phe(4-NH-Poc)-OH hydrochloride	ADC Linker	Others
H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported ^[2]. H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-116482R

Desmedipham (Standard)	Insecticide Herbicide Reference Standards	Others
Desmedipham (Standard) is the analytical standard of Desmedipham. This product is intended for research and analytical applications. Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction .

HY-130194

Azido-PEG5-CH2CO2H	ADC Linker PROTAC Linkers	Cancer
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-P2744

Ribulose bisphosphate carboxylase Ribulose 1,5-bisphosphate carboxylase	Biochemical Assay Reagents	Others
Ribulose bisphosphate carboxylase (Ribulose 1,5-bisphosphate carboxylase) catalyses the carboxylation (CO₂ addition) or oxygenation (O₂ addition) of d-ribulose-1,5-bisphosphate (RuBP) and the subsequent carbon–carbon cleavage to form two molecules of 3-phospho-d-glycerate (PGA) (with CO₂) or one molecule of PGA and one molecule of 2-phospho-glycolate (PG; with O₂) .

HY-W016613

Tri(ethylene glycol) monoethyl ether	Biochemical Assay Reagents	Others
Tri(ethylene glycol) monoethyl ether is a physical solvent with a strong affinity for CO₂. Tri(ethylene glycol) monoethyl ether can be used for the removal of acid gases from mixtures of gases .

HY-E70570

Glutamate decarboxylase	GABA Receptor	Metabolic Disease
Glutamate decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide (CO2). Many gut microbes can metabolize glutamate via their Glutamate decarboxylase in a pyridoxal-5′-phosphate (PLP) dependent manner .

HY-W004297R

1-Nonadecanol (Standard)	Reference Standards Others	Others
1-Nonadecanol (Standard) is the analytical standard of 1-Nonadecanol. This product is intended for research and analytical applications. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata ^[2].

HY-RS26685

*mt-Co2* Rat Pre-designed siRNA Set A**	Small Interfering RNA (siRNA)	Others
mt-Co2 Rat Pre-designed siRNA Set A contains three designed siRNAs for mt-Co2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

mt-Co2 Rat Pre-designed siRNA Set A mt-Co2 Rat Pre-designed siRNA Set A

HY-RS20181

*mt-Co2* Mouse Pre-designed siRNA Set A**	Small Interfering RNA (siRNA)	Others
mt-Co2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for mt-Co2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

mt-Co2 Mouse Pre-designed siRNA Set A mt-Co2 Mouse Pre-designed siRNA Set A

HY-140025

Propargyl-PEG4-CH2CO2-NHS	ADC Linker	Cancer
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-140747

BnO-PEG1-CH2CO2tBu	PROTAC Linkers	Cancer
BnO-PEG1-CH2CO2tBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-138350

Azido-PEG10-CH2CO2-NHS	PROTAC Linkers	Cancer
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140853

Azido-PEG3-CH2CO2Me	PROTAC Linkers	Cancer
Azido-PEG3-CH2CO2Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-CH2CO2Me is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140763

Azido-PEG1-CH2CO2-NHS	PROTAC Linkers	Cancer
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130693

Azido-PEG5-CH2CO2-PFP	PROTAC Linkers	Cancer
Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140191

Amino-PEG4-(CH2)3CO2H	PROTAC Linkers	Cancer
Amino-PEG4-(CH2)3CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140416

Boc-Aminooxy-PEG4-CH2CO2H	PROTAC Linkers	Cancer
Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W440953

Stearic acid-PEG1000-CH2CO2H	Biochemical Assay Reagents	Others
Stearic acid-PEG1000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

HY-W440954

Stearic acid-PEG2000-CH2CO2H	Liposome	Others
Stearic acid-PEG2000-CH2CO2H is a heterobifunctional polyPEG with 18-carbon aliphatic chain and carboxyl. The polymer has stearic acid as the hydrophobic tail and PEG as the hydrophilic chain, therefore it forms micelles in water. Carboxyl can react with amine in the presence of activator, such as HATU/EDC to generate a stable amide bond. Reagent grade, for research use only.

Cat. No.	Product Name	Type

HY-151644

Fluorescein hydrazide 1 Publications Verification	Fluorescent Dye
Fluorescein hydrazide is a sensitive fluorescent probe for Hg ²⁺ and Co ²⁺ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM ^[1][2][3].

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Fluorescent Dye
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release ^[2] .

HY-D2775

Cobalt(II) ions probe 1	Fluorescent Dye
Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co ²⁺ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co ²⁺ in the presence of other metal ions (Ex: 380 nm) .

Cat. No.	Product Name	Type

HY-D0227J

THAM hydrochloride (≥99%, for cell culture)

1 Publications Verification

Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)

Biochemical Assay Reagents

THAM hydrochloride (≥99%, for cell culture) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM hydrochloride (≥99%, for cell culture) binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM hydrochloride (≥99%, for cell culture) may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM hydrochloride (≥99%, for cell culture) removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM hydrochloride (≥99%, for cell culture) can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM hydrochloride (≥99%, for cell culture) is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications ^[2] .

HY-W011060

Cryptand 2.2.2

4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexaCosane

Biochemical Assay Reagents

Cryptand 2.2.2 (4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane) is a metal ion chelator. Cryptand 2.2.2 forms stable mononuclear, protonated and dinuclear complexes with copper (II) ions; forms protonated complexes with hydrogen ions; and also forms stable complexes with Zn ²⁺, Co ²⁺, Ni ²⁺, Cd ²⁺, Hg ²⁺ and Pb ²⁺ ions. Cryptand 2.2.2 can be used for the preparation of nanoparticles, transition metal compounds, etc.

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Polyvinyl alCohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Biochemical Assay Reagents

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections ^[2] .

HY-W007431

Methyl 3,4-diaminobenzoate	Biochemical Assay Reagents
Methyl 3,4-diaminobenzoate is an analogue of 3,4-diaminobenzoic acid, which contains the CO2H group protected as a methyl ester and the amino (NH2) substituents required to form the quinoxaline .

HY-W016613

Tri(ethylene glycol) monoethyl ether	Biochemical Assay Reagents
Tri(ethylene glycol) monoethyl ether is a physical solvent with a strong affinity for CO₂. Tri(ethylene glycol) monoethyl ether can be used for the removal of acid gases from mixtures of gases .

HY-W440953

Stearic acid-PEG1000-CH2CO2H	Biochemical Assay Reagents
Stearic acid-PEG1000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

HY-W011060R

Cryptand 2.2.2 (Standard)

4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexaCosane (Standard)

Biochemical Assay Reagents

Cryptand 2.2.2 (Standard) is the analytical standard of Cryptand 2.2.2 (HY-W011060). This product is intended for research and analytical applications. Cryptand 2.2.2 is a metal ion chelating agent that can selectively form complexes with metal ions. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn ²⁺, Co ²⁺, Ni ²⁺, Cu ²⁺). Cryptand 2.2.2 can be used in the preparation of nanoparticles, transition metal compounds, and so on .

HY-W440955

Stearic acid-PEG3400-CH2CO2H	Biochemical Assay Reagents
Stearic acid-PEG3400-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

HY-W440956

Stearic acid-PEG5000-CH2CO2H	Biochemical Assay Reagents
Stearic acid-PEG5000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

Cat. No.	Product Name	Target	Research Area

HY-P0294

Hexa-His 6X His Tag	Biochemical Assay Reagents	Others
Hexa-His (6X His Tag) is a commonly used affinity tag made up of six histidine residues. HEXA-HIS can bind to affinity chromatography media containing transition metal ions like nickel (Ni ²⁺) or cobalt (Co ²⁺), making it useful for protein purification ^[2].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-164642

Ribulose 1,5-bisphosphate RuBP	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
Ribulose 1,5-bisphosphate (RUBP) is a vital photosynthetic intermediate and substrate. Ribulose 1,5-bisphosphate acts as both product and substrate for Thermococcus kodakarensis KOD1 R15Pi. Ribulose 1,5-bisphosphate tightly binds to inactive RuBP carboxylase sites in plant leaves.Ribulose 1,5-bisphosphate serves as the key substrate for CO₂ fixation in photosynthesis. Ribulose 1,5-bisphosphate supports carboxylation and regeneration processes in photosynthesis. Ribulose 1,5-bisphosphate determines the dynamic transition temperature of photosynthetic control. Ribulose 1,5-bisphosphate can be used for photosynthesis and enzyme mechanism research ^[2] .

HY-W004297

1-Nonadecanol	Structural Classification Natural Products other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Drug Intermediate
1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO₂) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata ^[2].

HY-N3887

Evoxine Haplophytin B; Haplophytine B	Alkaloids Other Alkaloids Rutaceae Plants Haplophyllum acutifolium (DC.) G. Don Source Classification	Bacterial
Evoxine (Haplophytin B) is a compound that selectively inhibits CO2-induced immunosuppression and has activity in inhibiting the expression of interleukin-6 and chemokine CCL2 in human THP-1 macrophages. Evoxine shows antimicrobial activity against a wide range of bacteria, especially performing well in minimum inhibitory concentration (MIC) tests against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Evoxine extracts may find application in crude drug preparations in West Africa, provided that their in vivo toxicity results are negative .

HY-W004297R

1-Nonadecanol (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Others
1-Nonadecanol (Standard) is the analytical standard of 1-Nonadecanol. This product is intended for research and analytical applications. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata ^[2].

HY-150033

Sorgoleone	Quinones Structural Classification Sorghum bicolor (Linn.) Moench Gramineae Benzene Quinones Plants Source Classification	Photosystem II Herbicide
Sorgoleone is a photosystem II inhibitor found in sorghum. Sorgoleone binds to the Q_B niche of the D1 protein, inhibits photosynthetic electron transport, and does not affect photosystem I reactions. Sorgoleone reduces radicle elongation and stunts growth. Sorgoleone inhibits CO₂-dependent oxygen evolution, photosynthetic O₂ evolution, and mitochondrial respiration. Sorgoleone can be used as a herbicide ^[2] .

HY-180668

2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline is a product of the hydrolysis of 5-hydroxyisourate. 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline undergoes stereoselective decarboxylation by the action of 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase to give CO₂ and (S)-allantoin .

HY-W722245

Pyochelin	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Source Classification	Endogenous Metabolite Bacterial
Pyochelin is a salicylate-based nonribosomal peptide siderophore produced by Pseudomonas aeruginosa. Pyochelin chelates Fe ³⁺ and transports it back into bacterial cells, providing the iron essential for bacterial survival. Pyochelin can also chelate other metals such as Zn ²⁺, Co ²⁺, and Ni ²⁺, which helps bacteria maintain intracellular metal ion homeostasis by chelating and excreting excess metals in response to toxic metal stress. Pyochelin can be used in studies related to Pseudomonas aeruginosa infection ^[2] .

Species:	Human (2) Mouse (1) Cynomolgus (2) Dog (1) Pig (1)
Tag:	His (6) Avi (3) Fc (1)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700697

	C2/Complement C2 Protein, Cynomolgus (HEK293, His) Complement C2; C3/C5 Convertase; C2; ARMD14; Co2	Cynomolgus	HEK293
	Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1, resulting in the formation of two distinct fragments: C2b and C2a. The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b, leading to the formation of C3 or C5 convertase. C2/Complement C2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705296

	C2/Complement C2 Protein, Pig (Biotinylated, HEK293, His-Avi) Complement C2; C3/C5 Convertase; C2; ARMD14; Co2	Pig	HEK293

HY-P705191

	C2/Complement C2 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) Complement C2; C3/C5 Convertase; C2; ARMD14; Co2	Cynomolgus	HEK293

HY-P705290

	C2/Complement C2 Protein, Dog (Biotinylated, HEK293, His-Avi) Complement C2; C3/C5 Convertase; C2; ARMD14; Co2	Dog	HEK293

HY-P74374

	C2/Complement C2 Protein, Mouse (HEK293, His) Complement C2; C3/C5 Convertase; C2	Mouse	HEK293
	Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1, resulting in the formation of two distinct fragments: C2b and C2a. The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b, leading to the formation of C3 or C5 convertase. C2/Complement C2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74375

	C2/Complement C2 Protein, Human (HEK293, His) Complement C2; C3/C5 Convertase; C2	Human	HEK293
	C2/Complement C2 protein is essential in the classical pathway of the complement system. Activated by factor C1, C2 is cleaved into C2b and C2a. As a serine protease, C2a interacts with C4b, generating the C3 or C5 convertase. This crucial process activates and amplifies the complement cascade. C2/Complement C2 Protein, Human (HEK293, His) is the recombinant human-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74376

	C2/Complement C2 Protein, Human (HEK293, Fc) Complement C2; C3/C5 Convertase; C2	Human	HEK293
	C2/Complement C2 protein is essential in the classical pathway of the complement system. Activated by factor C1, C2 is cleaved into C2b and C2a. As a serine protease, C2a interacts with C4b, generating the C3 or C5 convertase. This crucial process activates and amplifies the complement cascade. C2/Complement C2 Protein, Human (HEK293, Fc) is the recombinant human-derived C2/Complement C2 protein, expressed by HEK293 , with C-hFc labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-118877

Urea-13C 1 Publications Verification
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

Host:	Mouse (2) Rabbit (4)
Reactivity:	Human (6) Rat (1) Mouse (1)
Application:	IHC-P (6) ICC/IF (2) IF-Tissue (2) IP (2) IHC-F (2) WB (4)
Isotype:	IgG (4) IgG1 (2)
Conjugation:	Non-conjugated (6) Biotin (3)
Clonality:	Polyclonal (1) Monoclonal (3) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88357

	C2 Antibody (YA8041) ARMD14; Co2	IHC-P	Human
	C2 Antibody (YA8041) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C2.

HY-P83509

	MTCO2 Antibody (YA3254) MT-Co2; CoX2; Co2; Cytochrome c oxidase II; MTCo2; CoII; CoXII	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	MTCO2 Antibody (YA3254) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MTCO2.

HY-P88357A

	C2 Antibody (YA8041)(PBS only) ARMD14; Co2	IHC-P	Human
	C2 Antibody (YA8041) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C2.

HY-P83509A

	MTCO2 Antibody (YA3254)(PBS only) MT-Co2; CoX2; Co2; Cytochrome c oxidase II; MTCo2; CoII; CoXII	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	MTCO2 Antibody (YA3254) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MTCO2.

HY-P81047

	Collagen II Antibody 1 Publications Verification Collagen II alpha 1; CoL2A1; CoL2A1 protein; Collagen, type II, alpha 1; Collagen alpha-1(II); type II Collagen; alpha-1 type II Collagen; alpha1 type II Collagen; Col2a1; AOM; Cartilage Collagen; Chondrocalcin; CoL11A3; Collagen alpha 1(II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia Congenital); MGC131516; SEDC; Collagen alpha-1(II) chain; Alpha-1 type II Collagen; Co2A1_HUMAN.; CollagenII;	WB, IHC-P, IF-Tissue	Human
	Collagen II Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Collagen II.

HY-P81047A

	Collagen II Antibody(YA3550) 1 Publications Verification Collagen II alpha 1; CoL2A1; CoL2A1 protein; Collagen, type II, alpha 1; Collagen alpha-1(II); type II Collagen; alpha-1 type II Collagen; alpha1 type II Collagen; Col2a1; AOM; Cartilage Collagen; Chondrocalcin; CoL11A3; Collagen alpha 1(II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia Congenital); MGC131516; SEDC; Collagen alpha-1(II) chain; Alpha-1 type II Collagen; Co2A1_HUMAN.; CollagenII;	WB, IHC-P, IF-Tissue	Human, Mouse, Rat
	Collagen II Antibody(YA3550) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Collagen II.

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Cat. No.	Product Name		Classification

HY-140766

Azido-PEG5-CH2CO2-NHS		PROTAC Synthesis Azide
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151824

Boc-L-Phe(4-NH-Poc)-OH		Alkynes
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported ^[2]. Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151837

H-L-Phe(4-NH-Poc)-OH hydrochloride		Alkynes
H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported ^[2]. H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130194

Azido-PEG5-CH2CO2H		PROTAC Synthesis ADC Synthesis Azide
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-138350

Azido-PEG10-CH2CO2-NHS		PROTAC Synthesis Azide
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140853

Azido-PEG3-CH2CO2Me		PROTAC Synthesis Azide
Azido-PEG3-CH2CO2Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-CH2CO2Me is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140763

Azido-PEG1-CH2CO2-NHS		Azide PROTAC Synthesis
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130693

Azido-PEG5-CH2CO2-PFP		PROTAC Synthesis Azide
Azido-PEG5-CH2CO2-PFP is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W1052510

N3-PEG2-CH2CO2-NHS		Azide
N3-PEG2-CH2CO2-NHS is a PEG derivative containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Cat. No.	Product Name		Classification

HY-RS08758

*MT-CO2* Human Pre-designed siRNA Set A**		siRNAs Human Pre-designed siRNA Sets
MT-CO2 Human Pre-designed siRNA Set A contains three designed siRNAs for MT-CO2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS26685

*mt-Co2* Rat Pre-designed siRNA Set A**		siRNAs Rat Pre-designed siRNA Sets
mt-Co2 Rat Pre-designed siRNA Set A contains three designed siRNAs for mt-Co2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS20181

*mt-Co2* Mouse Pre-designed siRNA Set A**		siRNAs Mouse Pre-designed siRNA Sets
mt-Co2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for mt-Co2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-W440953

Stearic acid-PEG1000-CH2CO2H		Pegylated Lipids
Stearic acid-PEG1000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

HY-W440954

Stearic acid-PEG2000-CH2CO2H		Pegylated Lipids
Stearic acid-PEG2000-CH2CO2H is a heterobifunctional polyPEG with 18-carbon aliphatic chain and carboxyl. The polymer has stearic acid as the hydrophobic tail and PEG as the hydrophilic chain, therefore it forms micelles in water. Carboxyl can react with amine in the presence of activator, such as HATU/EDC to generate a stable amide bond. Reagent grade, for research use only.

HY-RS01738

C2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
C2 Human Pre-designed siRNA Set A contains three designed siRNAs for C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-W440955

Stearic acid-PEG3400-CH2CO2H		Pegylated Lipids
Stearic acid-PEG3400-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

HY-W440956

Stearic acid-PEG5000-CH2CO2H		Pegylated Lipids
Stearic acid-PEG5000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.

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