106 Results for "

Cys663

" in MedChemExpress (MCE) Product Catalog:
Products (106)

106 Results for "Cys663" in MCE Product Catalog:

30
30 Publications Verification
Art. -Nr.: HY-17571
CAS. Nr.: 50-56-6
Synonyms: α-Hypophamine; Oxytocic hormone
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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30
30 Publications Verification
Art. -Nr.: HY-17571A
CAS. Nr.: 6233-83-6
Synonyms: α-Hypophamine acetate; Oxytocic hormone acetate
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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13
13 Cited Publications
Art. -Nr.: HY-106224
CAS. Nr.: 205640-90-0
Reinheit:  99.93%
Synonyms: Hypocretin-1 (human, rat, mouse)
Forschungsgebiete:  

Neurological Disease

Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .
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13
13 Cited Publications
Art. -Nr.: HY-106224B
Reinheit:  99.93%
Synonyms: Hypocretin-1 (human, rat, mouse) acetate
Forschungsgebiete:  

Neurological Disease

Orexin A (Hypocretin-1) (human, rat, mouse) acetate is a hypothalamic neuropeptide with analgesic properties (crosses the blood-brain barrier). Orexin A (human, rat, mouse) acetate binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) acetate can be used in studies of appetite regulation, neurodegenerative diseases and modulation of injurious messaging .
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13
13 Cited Publications
Art. -Nr.: HY-106224A
Reinheit:  97.13%
Synonyms: Hypocretin-1 (human, rat, mouse) TFA
Forschungsgebiete:  

Neurological Disease

Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)) TFA, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) TFA binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R). Orexin A (human, rat, mouse) TFA has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) TFA is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats .
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10
10 Cited Publications
Art. -Nr.: HY-P0049
CAS. Nr.: 113-79-1
Synonyms: Arg8-vasopressin; AVP
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
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10
10 Cited Publications
Art. -Nr.: HY-W539944
CAS. Nr.: 129979-57-3
Synonyms: Arg8-vasopressin acetate; AVP acetate
Forschungsgebiete:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
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7
7 Cited Publications
Art. -Nr.: HY-B1811
CAS. Nr.: 11000-17-2
Synonyms: Arginine vasopressin; Antidiuretic hormone
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .
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7
7 Cited Publications
Art. -Nr.: HY-17572A
CAS. Nr.: 914453-95-5
Synonyms: RW22164 acetate; RWJ22164 acetate
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .
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4
4 Cited Publications
Art. -Nr.: HY-P1408
CAS. Nr.: 404882-00-4
Target:  

Integrin VEGFR

Forschungsgebiete:  

Cancer

Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
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4
4 Cited Publications
Art. -Nr.: HY-P2222
CAS. Nr.: 478188-26-0
Forschungsgebiete:  

Cardiovascular Disease

DX600 is a selective ACE2 specific inhibitor (KD: 1.3 nM), and does not cross-react with ACE. DX600 exacerbates diabetes-induced cardiovascular dysfunction and the increase in cardiac and renal NOX activity .
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4
4 Cited Publications
Art. -Nr.: HY-P1408A
Target:  

Integrin

Forschungsgebiete:  

Cancer

Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .
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4
4 Cited Publications
Art. -Nr.: HY-P2222A
DX600 TFA is a selective ACE2 specific inhibitor (KD: 1.3 nM), and does not cross-react with ACE. DX600 TFA exacerbates diabetes-induced cardiovascular dysfunction and the increase in cardiac and renal NOX activity .
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3
3 Cited Publications
Art. -Nr.: HY-17573
CAS. Nr.: 37025-55-1
Target:  

Oxytocin Receptor

Forschungsgebiete:  

Neurological Disease Metabolic Disease

Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
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3
3 Cited Publications
Art. -Nr.: HY-P1237
CAS. Nr.: 127869-51-6
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .
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3
3 Cited Publications
Art. -Nr.: HY-A0182
CAS. Nr.: 56-59-7
Synonyms: PLV-2
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures .
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3
3 Cited Publications
Art. -Nr.: HY-A0182A
CAS. Nr.: 914453-97-7
Synonyms: PLV-2 acetate
Target:  

Vasopressin Receptor

Forschungsgebiete:  

Cardiovascular Disease

Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures .
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3
3 Cited Publications
Art. -Nr.: HY-17573A
CAS. Nr.: 1631754-28-3
Target:  

Oxytocin Receptor

Forschungsgebiete:  

Neurological Disease Metabolic Disease

Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
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3
3 Cited Publications
Art. -Nr.: HY-P1237A
CAS. Nr.: 1966153-17-2
C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .
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2
2 Cited Publications
Art. -Nr.: HY-P0004
CAS. Nr.: 50-57-7
Synonyms: Lysine vasopressin; [Lys8]-Vasopressin
Lysipressin (Lysine vasopressin ; [Lys8]-Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin depends on the sympathetic tone pathway. Lysipressin dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin can be used in studies related to cardiovascular regulation, hypertension and pain .
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