49 Results for "

Diammonium

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "Diammonium" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-110385
CAS No.: 2407516-83-8
Purity:  98.47%
Synonyms: Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium
cGAMP (Cyclic GMP-AMP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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27
27 Publications Verification
Cat. No.: HY-110385A
Purity:  95.19%
Synonyms: Cyclic GMP-AMP Diammonium; 3',3'-cGAMP Diammonium
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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19
19 Cited Publications
Cat. No.: HY-P0118B
Synonyms: P144 Diammonium
Research Areas:  

Cancer

Disitertide (P144) diammonium is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide diammonium is also a PI3K inhibitor and an apoptosis inducer .
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19
19 Cited Publications
Cat. No.: HY-12326B
Purity:  99.36%
Synonyms: Cyclic diadenylate Diammonium; Cyclic-di-AMP Diammonium
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .
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14
14 Cited Publications
Cat. No.: HY-15902
CAS No.: 30931-67-0
Purity:  99.86%
Synonyms: AzBTS-(NH4)2
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .
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10
10 Cited Publications
Cat. No.: HY-B1529
CAS No.: 3012-65-5
Synonyms: Ammonium hydrogencitrate, 99%; Diammonium hydrogen citrate, 99%
Ammonium citrate dibasic, 99% (Ammonium hydrogencitrate, 99%) can be used as the carbon source to prepare carbon quantum dots (CDs). Ammonium citrate dibasic, 99% is a buffering agent .
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9
9 Cited Publications
Cat. No.: HY-107780B
CAS No.: 609343-82-0
Purity:  99.07%
Synonyms: c-di-GMP Diammonium; cyclic diguanylate Diammonium; 5GP-5GP Diammonium
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research .
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5
5 Cited Publications
Cat. No.: HY-111999A
CAS No.: 2242635-03-4
Purity:  99.48%
Target:  

STING

Research Areas:  

Cancer

E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities .
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1
1 Cited Publications
Cat. No.: HY-Y0262A
CAS No.: 6009-70-7
Synonyms: Ethanedioic acid Diammonium monohydrate
Oxalic acid (Ethanedioic acid) diammonium monohydrate is a dicarboxylic acid found in a wide variety of plants.
Oxalic acid diammonium monohydrate shows antioxidant acyivity and suppresses lipid peroxidation.
Oxalic acid diammonium monohydrate is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid diammonium monohydrate exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease varroatosis and inflammatory diseases .
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1
1 Cited Publications
Cat. No.: HY-130115B
Purity:  98.79%
Target:  

STING

Research Areas:  

Cancer

IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy .
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1
1 Cited Publications
Cat. No.: HY-W012158
CAS No.: 19402-63-2
Synonyms: Sebacic acid ammonium; Ammonium decanedioate; Diammonium sebacate
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Decanedioic acid (ammonium) (Sebacic acid (ammonium); Ammonium decanedioate; Diammonium sebacate) is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-N6804
CAS No.: 79165-06-3
Diammonium glycyrrhizinate is a substance that can be extracted and purified from a traditional Chinese medicinal herb. Diammonium glycyrrhizinate has anti-inflammatory effect, resistance to biologic oxidation, membranous protection and a weak steroidal action. Diammonium glycyrrhizinate exerts protective effect by downregulating inflammation cytokines, suppressing the NF-κB pathway, and restoring superoxide dismutase. Diammonium glycyrrhizinate can be used as a hepatic protector and can therefore be studied in research for most liver diseases .
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Cat. No.: HY-146248B
Purity:  98.02%
TFMU-ADPr diammonium is a selective reporter substrate of SARS-CoV-2 Macro1 (IC50=0.59 μM), with an excitation wavelength (λEx) of 385 nm, and an emission wavelength (λEm) of 502 nm (or 495 nm). TFMU-ADPr diammonium can also undergo enzymatic hydrolysis with Poly(ADP-ribose) Glycohydrolase (PARG) sourced from human, Tetrahymena thermophila and ADP-ribosylhydrolase 3 from human to release fluorophores, thereby directly reporting total poly (ADP-ribose) hydrolase activity. TFMU-ADPr diammonium binds to the ADPr-binding site of SARS-CoV-2 Macro1, and its TFMU moiety inserts into the narrow hydrophobic groove of this protein. TFMU-ADPr diammonium can thus be used to evaluate small-molecule inhibitors targeting PAR hydrolases under in vitro conditions, to investigate the regulatory mechanisms of ADP-ribosyl catabolic enzymes, or to detect PAR hydrolase activity in whole-cell lysate assays. TFMU-ADPr diammonium is also applicable to COVID-19-related research .
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Cat. No.: HY-108657A
CAS No.: 2387505-47-5
Purity:  ≥98.0%
Target:  

P2Y Receptor

Research Areas:  

Neurological Disease

MRS2279 diammonium is a selective and high affinity P2Y1 receptor antagonist, with a Ki value of 2.5 nM and an IC50 value of 51.6 nM. MRS2279 diammonium competitively inhibits ADP-promoted platelet aggregation with an pKb value of 8.05 .
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Cat. No.: HY-Y0286A
CAS No.: 506-87-6
Synonyms: Carbonic acid Diammonium, 99.999% trace metals basis
Diammonium carbonate, 99.999% trace metals basis is a biochemical reagent and a buffer component .
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Cat. No.: HY-139100B
CAS No.: 75252-10-7
Purity:  99.15%
Synonyms: m7GpppA Diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine Diammonium
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .
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Cat. No.: HY-W105775
CAS No.: 2226-88-2
Synonyms: Ammonium succinate
Diammonium succinate (Ammonium succinate) is a hydrophobic hydrocarbon compound that can be used to study its interaction with microbial cells, especially the mechanisms of degradation and bioavailability. Diammonium succinate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research.
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Cat. No.: HY-W109973
CAS No.: 3164-29-2
Synonyms: L-(+)-Tartaric acid Diammonium
L-Tartaric acid diammonium (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. L-Tartaric acid diammonium has vasodilatory and antihypertensive effects. L-Tartaric acid diammonium can be used as flavorings and antioxidants in a range of foods and beverages. L-Tartaric acid diammonium can be used in laser frequency doubling and optical limiting applications .
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Cat. No.: HY-Y0302
CAS No.: 7783-28-0
Diammonium phosphate is a neutral and efficient catalyst in 1,8‐Dioxo‐octahydroxanthene derivatives synthesis. Diammonium phosphate can be used as an excipient, such as diuretic, buffer, effervescent .
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Cat. No.: HY-166114A
CAS No.: 103476-28-4
Synonyms: (Z)-Heptaprenyl phosphate Diammonium
Target:  

Bacterial

Research Areas:  

Infection

(Z)-Heptaprenyl-MPDA ((Z)-Heptaprenyl phosphate) diammonium is the (Z)-isomer of Heptaprenyl-MPDA (HY-166114). Heptaprenyl-MPDA (Heptaprenyl phosphate) is a short-chain homolog of undecaprenyl phosphate, is an endogenous substrate of Phospho-MurNAc-pentapeptide translocase (MraY). Heptaprenyl-MPDA can be used for bacterial infections research .
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