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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
127 Results for "
E6
" in MedChemExpress (MCE) Product Catalog:
Products (127)
127 Results for "E6" in MCE Product Catalog:
47
Research Areas:
Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells.
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Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
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Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research . Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .
20
Target:
Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
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9
9 Cited Publications
Cat. No.: HY-P73149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; Multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:
Human
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-16477
CAS No.: 220201-34-3
Synonyms: ME2906; Mono-L-aspartyl chlorin E6; NPE6
Target:
Research Areas:
Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
4
4 Cited Publications
Synonyms: VERU-111; ABI-231
Target:
Research Areas:
VERU-111 (ABI-231) is a potent and orally active α and β tubulin inhibitor, which displays strong antiproliferative activity, with an average IC50 of 5.2 nM against panels of melanoma and prostate cancer cell lines. VERU-111 (ABI-231) suppresses tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7, and has potential for the treatment of prostate cancer .
1
1
1 Cited Publications
Target:
Research Areas:
Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) .
Target:
Cat. No.: HY-P99183
CAS No.: 1105038-73-0
Synonyms: EMD 525797; DI17E6
Cat. No.: HY-120997
CAS No.: 114784-59-7
Synonyms: Berbamine p-nitrobenzoate
Target:
Research Areas:
E6 Berbamine (Berbamine p-nitrobenzoate) is a potent calmodulin (CaM) antagonist. E6 Berbamine inhibits the activities of calmodulin-dependent myosin light chain kinase (MLCK) and phosphodiesterase (PDE). E6 Berbamine exhibits anti-leukemic activity. E6 Berbamine can be used in research related to cardiovascular abnormalities and chronic myeloid leukemia .
Cat. No.: HY-160506
CAS No.: 2353493-69-1
Target:
Research Areas:
PRO-6E is an oral active PROTAC based on Cereblon ligand, and induces the degradation of MET with maximum degradation of 81.9% at 1 μM in MKN-45 cells. PRO-6E inhibits tumor growth in vivo and in vitro. PRO-6E induces cell apoptosis and induces cell arrest .
Target:
Niclosamide (Standard) is the analytical standard of Niclosamide. This product is intended for research and analytical applications. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
Cat. No.: HY-140735
Purity: ≥95.0%
DSPE-PEG5000-Amine (DSPE-PEG5000-ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine is applicable to research related to PEGylated lipid functionalization and bioconjugation .
Cat. No.: HY-158189
CAS No.: 3030629-73-0
Research Areas:
TPP-Ce6 is a mitochondria-targeted photosensitizer formed by the ester bond conjugation of chlorophyll e6 (Ce6) with triphenylphosphine (TPP). Under light irradiation or ultrasound exposure, TPP-Ce6 generates reactive oxygen species, induces cell apoptosis, and triggers immunogenic cell death. TPP-Ce6 can serve as a component of carrier-free co-delivery systems, undergo enzyme-induced self-assembly within tumors, and modulate tumor hypoxia. TPP-Ce6 is applicable to research on breast cancer and glioblastoma [6].
Cat. No.: HY-172265
CAS No.: 3115268-06-6
FKBP12 PROTAC FM4 is a PROTAC degrader of FKBP12, with a DC50 value of 0.09-0.22 nM. FKBP12 PROTAC FM4 inhibits global protein synthesis, induces apoptosis, and selectively reduces the viability of cervical cancer cells expressing MTH1-E6 and FKBP12 F36V-tagged SARS1. FKBP12 PROTAC FM4 is applicable to research related to HPV-positive cervical cancer .
Cat. No.: HY-155907
CAS No.: 474922-26-4
Synonyms: DSPE-PEG5000-NH2 ammonium
DSPE-PEG5000-Amine ammonium (DSPE-PEG5000-NH2 ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine ammonium can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine ammonium is applicable to research related to PEGylated lipid functionalization and bioconjugation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
