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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
443 Results for "
Factor D
" in MedChemExpress (MCE) Product Catalog:
Products (443)
443 Results for "Factor D" in MCE Product Catalog:
147
147 Publications Verification
Necrosulfonamide is a MLKL and Gasdermin D (GSDMD) inhibitor, capable of separately inhibiting necroptosis and pyroptosis of cells. Necrosulfonamide does not affect the activation of upstream signals, but specifically inhibits the downstream executor oligomerization step. Necrosulfonamide reduces the expression of the key kinases NLRP3 and caspase-1 involved in necroptosis and pyroptosis, activate the Nrf2 pathway and the downstream antioxidant enzymes, and also downregulates a variety of inflammatory factors. Necrosulfonamide plays significant roles in various diseases such as neurodegenerative diseases (such as Parkinson’s disease), tissue damage and ischemia-reperfusion injury, inflammatory bowel disease, osteoarthritis and fracture repair, and hair loss by regulating two important programmed necrosis pathways .
9
9 Cited Publications
Cat. No.: HY-P70593
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN1; Epididymis Secretory Sperm Binding Protein; Fibronectin 1; Fibronectin Splice Variant A; CIG; Fibronectin Splice Variant B; Cold-Insoluble Globulin; Fibronectin Splice Variant C; Lnc-ABCA12-8; Fibronectin Splice Variant D; Fibronectin; Fibronectin Splice Variant E; GFND2; Fibronectin Splice Variant F; LETS; FN1 Protein; FINC; SMDCF; MSF; ED-B; Migration-Stimulating Factor; GFND; FN; FNZ
Species:
Human
Source:
E. coli
7
7 Cited Publications
Cat. No.: HY-P74474
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFC; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor-Related Protein; VRP; VEGF-C; Flt4 Ligand; Flt4-L; FLT4 Ligand DHM; LMPH1D; LMPHM4
Species:
Mouse
Rat
Source:
HEK293
6
6 Cited Publications
Cat. No.: HY-P7121
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HGF; Hepatocyte Growth Factor (Hepapoietin A; Scatter Factor); Prev. DFNB39; Lung Fibroblast-Derived Mitogen; HPTA; Hepatopoietin-A; SF; Scatter Factor; F-TCF; Deafness, Autosomal Recessive 39; HGFB; Hepatopoietin A; Hepatocyte Growth Factor; Fibroblast-D
Species:
Human
Source:
CHO
6
6 Cited Publications
Synonyms: 4-Caffeoylquinic acid; 4-O-Caffeoylquinic acid
5
Target:
Research Areas:
Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
5
5 Cited Publications
Cat. No.: HY-P7084
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; Human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Mouse
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P7049
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; Human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Human
Source:
E. coli
5
5 Cited Publications
Cat. No.: HY-P73276
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: LIF; Hepatocyte-Stimulating Factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing Factor; HILDA; Melanoma-Derived LPL Inhibitor; Leukemia Inhibitory Factor; Human Interleukin In DA Cells; CDF; D Factor; DIA; MLPLI; Differentiation Inhibi
Species:
Human
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P7039
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL22; TIFa; Interleukin 22; IL-10-Related T-Cell-Derived Inducible Factor; IL-TIF; Cytokine Zcyto18; ILTIF; Interleukin-22; IL-22; MGC79382; TIFIL-23; MGC79384; Zcyto18; IL-10-Related T-Cell-Derived-Inducible Factor; IL-D110; Interferon 2B1; IL-21; ZCYTO1
Species:
Human
Source:
E. coli
3
3
3 Cited Publications
Cat. No.: HY-P7280
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFD; Platelet-Derived Growth Factor D; Platelet Derived Growth Factor D; Iris-Expressed Growth Factor; SCDGF-B; SCDGFB; IEGF; PDGF-D; MSTP036; Spinal Cord Derived Growth Factor B; Spinal Cord-Derived Growth Factor B
Species:
Human
Source:
CHO
3
3 Cited Publications
Cat. No.: HY-P77857
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFA; Transforming Growth Factor, Alpha; Transforming Growth Factor Alpha; TGF-Alpha; Protransforming Growth Factor Alpha; TFGA; Transforming Growth Factor, Alpha, Isoform CRA_d
Species:
Mouse
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-P7313
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VEGFC; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor-Related Protein; VRP; VEGF-C; Flt4 Ligand; Flt4-L; FLT4 Ligand DHM; LMPH1D; LMPHM4
Species:
Human
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-P80900
Synonyms: SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription Factor 1
3
3 Cited Publications
Cat. No.: HY-P72793
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL22; TIFa; Interleukin 22; IL-10-Related T-Cell-Derived Inducible Factor; IL-TIF; Cytokine Zcyto18; ILTIF; Interleukin-22; IL-22; MGC79382; TIFIL-23; MGC79384; Zcyto18; IL-10-Related T-Cell-Derived-Inducible Factor; IL-D110; Interferon 2B1; IL-21; ZCYTO1
Species:
Mouse
Source:
CHO
2
2 Cited Publications
Synonyms: ALXN2050; ACH 0145228; ACH-5228
Target:
Research Areas:
Vemircopan (ALXN2050) is an orally active complement factor D (FD) inhibitor. Vemircopan can be used in the research of diseases such as myasthenia gravis, lupus nephritis, IgA nephropathy, and paroxysmal nocturnal hemoglobinuria .
2
2 Cited Publications
Cat. No.: HY-K6004
MCE Growth Factor Reduced Basement Membrane Matrix (Phenol Red-Free) is primarily composed of natural basement membrane matrix extracted from mouse tumors and contains abundant extracellular matrix components and a variety of naturally occurring growth factors. This product is primarily designed for 3D organoid culture and other research applications requiring high-quality basement membrane matrix. The phenol red-free formulation avoids potential interference with experiments requiring subsequent colorimetric or color-based analysis.
2
2 Cited Publications
Cat. No.: HY-K6008
MCE High-Concentration Basement Membrane Matrix (Phenol Red-Free) is primarily composed of natural basement membrane matrix extracted from mouse tumors. It is rich in extracellular matrix components and various naturally occurring growth factors, and is mainly used for the establishment of animal models and 3D tumor models.
2
2 Cited Publications
Cat. No.: HY-P7079
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL22; TIFa; Interleukin 22; IL-10-Related T-Cell-Derived Inducible Factor; IL-TIF; Cytokine Zcyto18; ILTIF; Interleukin-22; IL-22; MGC79382; TIFIL-23; MGC79384; Zcyto18; IL-10-Related T-Cell-Derived-Inducible Factor; IL-D110; Interferon 2B1; IL-21; ZCYTO1
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
