Search Result
Results for "
Fluorescent Probe
" in MedChemExpress (MCE) Product Catalog:
2442
Inhibitors & Agonists
46
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D0080
-
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Fluorescent Dye
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Others
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Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
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- HY-D0208
-
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Uranine sodium
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Environmental Pollutants
Fluorescent Dye
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Cancer
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Fluorescein (Uranine) sodium is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) sodium is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
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- HY-D1533
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Fluorescent Dye
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Others
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RhoNox-1 is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe 2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe 2+ in living cells, and tends to be localized in the Golgi apparatus .
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- HY-D0085
-
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Fluorescent Dye
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Cancer
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DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC50 value is 8 μM. DiSC3(5) in the presence of Na +/K +-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .
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- HY-126561
-
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CMFDA
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Fluorescent Dye
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Others
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Green CMFDA is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .
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- HY-D1041
-
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ICG-OSu
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Fluorescent Dye
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Cancer
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ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
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- HY-W751238
-
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DMMB
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Fluorescent Dye
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Others
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Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye. Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin, releasing DMMB and increasing the fluorescence intensity. Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E. Coli) endotoxin . Dimethyl methylene blue zinc chloride double salt can be used for the quantification of sulfated glycosaminoglycans .
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- HY-43520
-
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Fluorescent Dye
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Others
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BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .
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- HY-DY1046
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Fluorescent Dye
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Others
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Green CMFDA (solution) is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .
Solvent and concentration: DMSO: 10 mM
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- HY-D0133
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Fluorescent Dye
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Others
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NBD-X acid is a fluorescent probe containing a nitrobenzoxadiazole group. NBD-X acid can be used to study the structure and function of biomolecules .
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- HY-D0807
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5-IAF
1 Publications Verification
5-Iodoacetamidofluorescein
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Fluorescent Dye
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Cancer
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5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains) .
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- HY-D2367
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N-Hydroxysuccinimidyl rhodamine B ester
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Fluorescent Dye
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Others
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Rhodamine B NHS ester (N-Hydroxysuccinimidyl rhodamine B ester) is an amine-reactive fluorescent probe (λex/λem: 564/589 nm, respectively). Rhodamine B NHS ester could react with Glycine (HY-Y0966) .
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- HY-135009
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DASPI
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G-quadruplex
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Others
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2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .
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- HY-115691
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Styrene-BODIPY; Styrene-Conjugated BODIPY
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Fluorescent Dye
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Others
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STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .
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- HY-DY1025
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Fluorescent Dye
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Others
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Laurdan (solution) is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.
Solvent and concentration: DMSO: 5 mM
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- HY-W088089
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Fluorescent Dye
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Cancer
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ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
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- HY-D1046
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Dabcyl, SE
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Fluorescent Dye
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Others
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Dabcyl acid, SE is the amine-reactive form of Dabcyl acid (DABCYL) (HY-D1045), and is widely used in the preparation of fluorescent probes containing DABCYL .
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- HY-D1694
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Fluorescent Dye
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Others
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LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH .
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- HY-DY1030
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Fluorescent Dye
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Others
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RhoNox-1 (solution) is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe 2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm). FeRhoNox-1 can enter the cell well, suitable for the detection of Fe 2+ in living cells, and tends to be localized in the Golgi apparatus .
Solvent and concentration: DMSO: 5 mM
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- HY-D1602
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Fluorescent Dye
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Others
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BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λex=505 nm, λem=511 nm) .
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- HY-118155
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ACMA
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Fluorescent Dye
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Others
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9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
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- HY-117468
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Fluorescent Dye
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Others
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Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays .
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- HY-D1459
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Fluorescent Dye
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Metabolic Disease
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BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .
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- HY-W013967
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Fluorescent Dye
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Infection
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1,6-Diphenylhexa-1,3,5-triene is a membrane intercalator and hydrophobic fluorescent probe. 1,6-Diphenylhexa-1,3,5-triene intercalates into the non-polar region of lipid bilayers of adipocyte membranes with probe/membrane equilibrium affected by temperature, probe concentration, and membrane concentration. 1,6-Diphenylhexa-1,3,5-triene’s fluorescence intensity correlating with adipocyte membrane probe incorporation (Ex/Em = 350/452 nm) .
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- HY-113870
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Fluorescent Dye
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Others
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6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques .
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- HY-130015
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Reactive Oxygen Species (ROS)
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Others
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HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
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- HY-130017
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Reactive Oxygen Species (ROS)
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Others
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HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
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- HY-147652
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DNA Stain
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Others
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G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity .
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- HY-129811
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Microtubule/Tubulin
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Neurological Disease
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Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a Kd of 2 μM . Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations .
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- HY-W140203
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Fluorescent Dye
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Others
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2-(2′-Hydroxyphenyl) benzimidazole is the most extensively studied excited-state intramolecular proton transfer (ESIPT) molecule, exhibiting normal and tautomer emissions. 2-(2′-Hydroxyphenyl) benzimidazole has been applied as a fluorescent probe in various systems .
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- HY-D0941
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Fluorescent Dye
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Others
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5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .
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- HY-D2312
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Fluorescent Dye
Ferroptosis
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Cancer
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Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
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- HY-124197
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Fluorescent Dye
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Others
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Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
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- HY-D2864
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Fluorescent Dye
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Others
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Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
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- HY-151776
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TZ-Cy3
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Fluorescent Dye
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Others
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Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .
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- HY-171179
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Fluorescent Dye
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Neurological Disease
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BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo .
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- HY-W267364
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C343
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Fluorescent Dye
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Others
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Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500 .
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- HY-149102
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- HY-139646
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Fluorescent Dye
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Neurological Disease
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KMG-104 is a cell-impermeant highly selective fluorescent Mg 2+ probe. KMG-104 has been used widely and revealed Mg 2+ mobilization in cytoplasm in various types of cells .
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- HY-W040681
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- HY-147889
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Apoptosis
Caspase
Bcl-2 Family
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Others
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BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .
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- HY-D1151
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HKOH-1
3 Publications Verification
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Reactive Oxygen Species (ROS)
Fluorescent Dye
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Others
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HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
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- HY-D1265
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HClO-green
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Fluorescent Dye
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Others
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EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
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- HY-D1685
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Fluorescent Dye
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Others
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BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease .
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- HY-136957
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Fluorescent Dye
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Others
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Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with Kds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively .
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- HY-DY1072
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ICG-OSu (solution)
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Fluorescent Dye
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Cancer
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ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
Solvent and concentration: DMSO: 10 mM
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- HY-D1478
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Fluorescent Dye
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Others
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Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
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- HY-D2476
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Fluorescent Dye
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Others
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H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
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- HY-D1302
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Fluorescent Dye
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Others
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Near-IR fluorescent probe-1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2418
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Fluorescent Dye
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Metabolic Disease
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PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .
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- HY-D1631A
-
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Fluorescent Dye
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Neurological Disease
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Calcium green-5N hexapotassium is a cell-impermeant Ca 2+-sensitive fluorescent probe. Calcium green-5N hexapotassium shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
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- HY-130022
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Fluorescent Dye
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Others
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HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
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- HY-151890
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Fluorescent Dye
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Cancer
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NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
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- HY-D1254
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NBL-SS perchlorate
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Fluorescent Dye
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Others
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Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .
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- HY-D2267
-
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Fluorescent Dye
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Others
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JF646-Hoechst is a fluorescent red DNA probe that is an ideal substitute for large oligonucleotide-coupled antibodies used in PAINT experiments, especially for bacterial studies. JF646-Hoechst excitation/emission maximum =655/670 nm .
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- HY-130027
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HKOCl-4
1 Publications Verification
BXY2142
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Fluorescent Dye
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Others
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HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
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- HY-D2377
-
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Fluorescent Dye
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Others
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F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .
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- HY-D1883
-
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Fluorescent Dye
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Others
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Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-P3791
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Fluorescent Dye
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Others
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N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .
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- HY-D0159
-
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Fluorescent Dye
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Others
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ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn 2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm .
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- HY-D0159A
-
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Fluorescent Dye
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Others
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ZnAF-1F tetraTFA is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn 2+ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm .
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- HY-D1595
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Fluorescent Dye
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Others
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BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .
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- HY-D2317
-
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Fluorescent Dye
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Others
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HaloFlipper 30 is a fluorescent probe that covalently reacts with HaloTag fusion proteins to form an ester bond, which allows the probe to be stably attached to membrane structures. HaloFlipper 30 has high specificity, precision and good cell permeability .
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- HY-151801
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mAChR
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Others
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DIBA-Cy5 is a fluorescent DIBA antagonist made up be DIBA-alkyne binding Cyanine5 fluorophores (Cy5) and polyethylene glycol (PEG) biomolecules. DIBA-Cy5 can serve as a fluorescent ligand, suitable for probe attachment through click chemistry. DIBA-Cy5 exerts a high binding affinity to type-2 mAChR (M2R) with the Kd value of 1.80 nM, can directly stain M2R receptors in the sinoatrial node of a mouse heart .
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- HY-W337618
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Fluorescent Dye
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Cancer
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7-Aminocoumarin is highly fluorescent, acts as an optical brightener and fluorescent probe .
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- HY-D2115
-
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Fluorescent Dye
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Others
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NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .
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- HY-161164
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DNA Stain
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Others
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Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm .
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- HY-D1391
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PbS/CdSe QD
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Fluorescent Dye
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Others
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PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
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- HY-155395
-
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Fluorescent Dye
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Infection
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DDAN-MT is an enzymatic activated near-infrared fluorescent probe. DDAN-MT can be used for rapid, highly selective, and real-time monitoring of endogenous MtMET-AP1 activity in M. tuberculosis .
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- HY-D1609
-
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Fluorescent Dye
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Others
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BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .
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- HY-172333
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Fluorescent Dye
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Others
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HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm .
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- HY-D1637
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Fluorescent Dye
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Others
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5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM) .
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- HY-D2999
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Fluorescent Dye
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Metabolic Disease
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NIR-RED ATP Probe is a NIR-II fluorescent probe. NIR-RED ATP Probe exhibits high affinity and selectivity for ATP and can non-invasively and with high contrast detect changes in ATP concentration at the cellular level, with minimal interference to the abundant biomolecules within the cells. NIR-RED ATP Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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- HY-W020798
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Fluorescent Dye
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Others
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1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma .
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-
![1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine](//file.medchemexpress.com/product_pic/hy-w020798.gif)
- HY-D2280
-
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HDAC
Estrogen Receptor/ERR
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Others
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Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .
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- HY-D1883A
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Fluorescent Dye
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Others
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Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-147177
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .
|
-
- HY-D2474
-
|
|
Fluorescent Dye
|
Cancer
|
|
PSP is a two-photon fluorescent probe for selective and sensitive detection of H2Sn in live cells and tumor spheroids (Ex/Em = 440/640 nm). PSP can be utilized in ferroptosis research .
|
-
- HY-D2260
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .
|
-
- HY-D2322
-
|
|
Fluorescent Dye
|
Others
|
|
SupraFlipper 31 is a fluorescent probe. SupraFlipper 31 can be released in the membrane of interest (MOI) via chemical stimulation.
|
-
- HY-162129
-
|
|
Photosensitizer
|
Cancer
|
|
Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .
|
-
- HY-W012642A
-
|
|
DNA Stain
|
Others
|
|
2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence .
|
-
- HY-126829
-
|
|
HDAC
|
Cancer
|
|
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes .
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-
- HY-D1527
-
|
|
Fluorescent Dye
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Others
|
|
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
|
-
- HY-136672
-
|
|
Fluorescent Dye
|
Others
|
|
(E)-HBT-O is an isomer of HBT-O. HBT-O is a fluorescent probe used to monitor subtle pH fluctuations in living cells .
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-
- HY-163098
-
|
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Fluorescent Dye
|
Others
|
|
JJ-OX-007 is a fluorescent probe which selectively for FphE in live S.aureus cells .
|
-
- HY-W411215
-
|
|
Fluorescent Dye
|
Others
|
|
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .
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-
- HY-145882
-
|
|
Fluorescent Dye
|
Others
|
|
BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway .
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-
- HY-151544
-
|
|
Fluorescent Dye
|
Others
|
|
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .
|
-
- HY-146343
-
-
- HY-160240
-
|
|
Fluorescent Dye
|
Others
Cancer
|
|
HPI is a HS - fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS - form of hydrogen sulfide (H2S) gas in environmental water samples .
|
-
- HY-139404
-
|
Anthrylvinyl ceramide; AV Ceramide; AV Ceramide (d18:1/10:0)
|
Fluorescent Dye
|
Others
|
|
C10 AV Ceramide (d18:1/10:0) is a fluorescent probe. Anthrylvinyl (AV) acts as the fluorescent label positioned on the amide linked acyl chain on the Ceramide molecule to measure the CERT-mediated transfer. The anthrylvinyl moiety of C10 AV Ceramide (d18:1/10:0) localizes to the hydrophobic region of the bilayer .
|
-
- HY-D2964
-
|
|
Fluorescent Dye
|
Others
|
|
NBzF-BG is a novel H2O2-specific fluorescent probe. NBzF-BG shows visible absorption centered at 505 nm and weak fluorescence with an emission maximum at 525 nm. NBzF-BG is covalently and selectively conjugated with the SNAP-tag protein, leading to formation of the fluorophore-protein conjugate (SNAP-NBzF). SNAP-NBzF rapidly reacts with H2O2 and thereby shows an enhancement in fluorescence .
|
-
- HY-D2376
-
|
|
Fluorescent Dye
|
Cancer
|
|
BH-Vis is a two-photon fluorescent probe that inhibits cell plasma membrane (CPM). BH-Vis has great potential to accurately identify pyroptosis at the cellular level during AAA development in the mouse abdominal aortic aneurysm AAA model .
|
-
- HY-142521
-
|
|
Leukotriene Receptor
|
Metabolic Disease
|
|
BLT2 probe 1 (compound 13) is a fluorescent probe based on the synthetic BLT2 agonist CAY10583. BLT2 is a promising target for diabetic wound healing and gastrointestinal lesions. BLT2 probe 1 is suitable to investigate the pharmacology of BLT2 receptor ligands in a variety of assay systems .
|
-
- HY-D3011
-
|
2-(9-Anthroyloxy)stearic acid
|
Fluorescent Dye
|
Others
|
|
2-AS is a fluorescent probe and can monitor the microenvironment and dynamic changes of biofilms .
|
-
- HY-130510
-
|
|
Fluorescent Dye
|
Others
|
|
6-HEX dipivaloate is an amino-bindable fluorescent probe that can be used to label peptides and oligonucleotides. 6-HEX dipivaloate is widely used in nucleic acid sequencing and related research .
|
-
- HY-D3239
-
|
AF405; Alexa Fluor 405 succinimidyl ester
|
Fluorescent Dye
OAT
|
Others
|
|
AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1 .
|
-
- HY-B0389F1
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
FITC-D-Glucose is a fluorescently labeled glucose derivative and an orally effective bacterial metabolic activity detection probe. FITC-D-Glucose is applicable to the research of cholera .
|
-
- HY-P11595
-
|
|
Fluorescent Dye
|
Cancer
|
|
TBZ-1 is a fluorescent probe that monitors the activity of immunoproteasome (Proteasome) (iCP) in cells. TBZ-1 undergoes fluorescence activation after being selectively cleaved by β5i, which is used for intracellular activity monitoring. TBZ-1 is applicable to cancer-related research .
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-
- HY-D1506
-
|
|
Fluorescent Dye
|
Others
|
|
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-110128
-
|
SF7-AM
|
Fluorescent Dye
|
Others
|
|
Sulfidefluor 7-AM is a stable hydrogen sulphide (H2S) fluorescent probe . Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-163895
-
|
|
Fluorescent Dye
Opioid Receptor
|
Neurological Disease
|
|
δ opioid receptor antagonist 1 (compound 6-Cy3) is a fluorescent antagonist probe with high selectivity for δ opioid receptor (DOR) (Ki=1.7 nM). δ opioid receptor antagonist 1 can be used to study the mechanism of pain perception .
|
-
- HY-W110898
-
|
|
Fluorescent Dye
|
Others
|
|
Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .
|
-
- HY-D0050
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester (cDCFDASE) is a fluorescent probe. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester can be used to evaluate the intracellular pH (pHin) of living cells at a medium pH (pHex) .
|
-
- HY-164801
-
|
|
Drug Intermediate
|
Others
|
|
Nile Red phenoxyacetic acid (Compound 4) is a pharmaceutical intermediate that can be used for the synthesis of GPR84 fluorescent probes .
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-
- HY-20794
-
|
|
Fluorescent Dye
|
Others
|
|
8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .
|
-
- HY-110210
-
|
BODIPY FL,SE
|
Fluorescent Dye
|
Others
|
|
BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
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-
- HY-D3267
-
|
|
Fluorescent Dye
|
Others
|
|
ACu1 is a copper (I)-selective two-photon fluorescent probe that enables the visual imaging of Cu + distribution in living cells and tissues .
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-
- HY-D1460
-
|
|
Bacterial
β-glucuronidase
|
Infection
|
|
Fluorescein Di-β-D-Glucuronide is an orally active fluorescent probe substrate and an indicator of β-glucuronidase (βG) activity in intestinal bacteria. Fluorescein Di-β-D-Glucuronide can be used for non-invasive time-lapse optical imaging of βG activity in intestinal bacteria in nude mice. Fluorescein Di-β-D-Glucuronide supports the quantitative analysis of bacterial βG enzyme activity and inhibition .
|
-
- HY-157765
-
|
|
PROTACs
Estrogen Receptor/ERR
|
Cancer
|
|
PROTAC ERα Degrader-6 (compound A2) is a potent PROTAC degrader of ERα, with IC50 of 0.11 μM in MCE-7 cells. PROTAC ERα Degrader-6 has anti-tumor effect. PROTAC ERα Degrader-6 is a fluorescent probes with Em of 582 nm that enable real-time visualization of ERα protein degradation .
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-
- HY-D1636
-
|
|
Fluorescent Dye
|
Others
|
|
5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca 2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca 2+ specific chelators, Ca 2+ buffers, and fluorescent Ca 2+ indicators .
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-
- HY-D1591
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .
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-
- HY-D3000
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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-
- HY-162543
-
|
18:1 Lissamine rhodamine PE
|
Fluorescent Dye
|
Others
|
|
18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .
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-
- HY-135640
-
-
- HY-155062
-
|
|
Mitochondrial Metabolism
Reactive Oxygen Species (ROS)
β-catenin
Fluorescent Dye
PPAR
|
Cancer
|
|
IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ, and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis .
|
-
- HY-U00440
-
-
- HY-D2941
-
|
SNAP-AF
|
Fluorescent Dye
|
Others
|
BGAF (SNAP-AF) is a fluorescent diacetyl fluorescein-labeled SNAP tag fluorescent probe, specifically designed for the covalent labeling of SNAP-tag fusion proteins in living cells. BGAF utilizes the specific reaction of the human DNA repair protein hAGT to achieve specific fluorescent labeling of the target protein in the living cell environment .
|
-
- HY-124473
-
|
Naphthafluorescein
|
HIF/HIF Prolyl-Hydroxylase
|
Cancer
|
|
Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.
Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
|
-
- HY-136214
-
|
|
Integrin
|
Inflammation/Immunology
Cancer
|
|
R-BC154 acetate is a selective fluorescent α9β1 integrin antagonist. R-BC154 acetate acts as a useful high affinity, activation dependent integrin probe, which can be used to investigate α9β1 and α4β1 integrin binding activity .
|
-
- HY-W091541
-
|
4-Hydroxyindole-3-carboxaldehyde
|
Endogenous Metabolite
|
Others
Inflammation/Immunology
|
|
4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .
|
-
- HY-W753658
-
|
|
Fluorescent Dye
|
Others
|
|
Coppersensor-3 (CS3) is a bright small-molecule fluorescent probe for selective Cu(I) detection. Coppersensor-3 is selective and sensitive enough to image labile copper pools in living cells at endogenous, basal levels. Coppersensor-3 can be used for the cell biology of copper research .
|
-
- HY-D3007
-
|
|
Fluorescent Dye
|
Others
|
|
LD-CK is a fluorescent probe based on a coumarin-chromone structure, specifically designed to visualize lipid droplet polarity changes and endowed with multimodal imaging capability. LD-CK contains a high-performance lipophilic coumarin moiety, which enables it to specifically target lipid droplets upon cellular entry while minimizing background fluorescence to the greatest extent. LD-CK has an excitation wavelength (Ex) of 488 nm and an emission wavelength (Em) of 540 nm (in low-polarity environments such as toluene) or 640 nm (in high-polarity environments such as glycerol), with its emission peak undergoing a redshift as solvent polarity increases .
|
-
- HY-D3180
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Neurological Disease
|
|
CDr20 is a fluorescent chemical probe capable of crossing the blood-brain barrier. CDr20 undergoes glucuronidation catalyzed by the UDP-glucuronosyltransferase Ugt1a7c, which triggers a fluorescence turn-on response. CDr20 enables visualization of live microglial cells. CDr20 can be used for research on Alzheimer's disease, stroke, and autism .
|
-
- HY-110334
-
|
|
Fluorescent Dye
|
Others
|
|
FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles .
|
-
- HY-D0077
-
|
Oregon green 488
|
Fluorescent Dye
|
Others
|
|
2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
|
-
- HY-D1770
-
-
- HY-D1898
-
|
|
Fluorescent Dye
|
Others
|
|
6-TET Azide is a fluorescent probe that can be used for the preparation of fluorescent contrast agent and nucleic acid sequencing .
|
-
- HY-D2967
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Golgi-NO is a Golgi-targeted fluorescent probe for nitric oxide (NO) (Ex/Em: 560 nm/589 nm). Golgi-NO exhibits excellent selectivity for various potential interfering substances. Golgi-NO can be used to study the function of NO within the Golgi apparatus in disease models such as Alzheimer's disease (AD) .
|
-
- HY-W008048
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
|
-
- HY-D1458
-
-
- HY-139014
-
|
H-L-Lys(Poc)-OH
|
Fluorescent Dye
|
Cancer
|
|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-135637
-
|
|
Fluorescent Dye
|
Others
|
|
Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-D1528
-
-
- HY-D2943
-
|
SNAP-SS-SulfoCy3
|
Fluorescent Dye
|
Others
|
|
BG-SS-SulfoCy3 is a SulfoCy3-labeled SNAP tag fluorescent probe, which is linked by a disulfide bond to achieve selective labeling and controllable cleavage. BG-SS-SulfoCy3 can be used to study the endocytosis and trafficking of membrane proteins such as GPCRs .
|
-
- HY-W091541R
-
|
4-Hydroxyindole-3-carboxaldehyde (Standard)
|
Endogenous Metabolite
Reference Standards
|
Others
Inflammation/Immunology
|
|
4-Hydroxy-1H-indole-3-carbaldehyde (Standard) is the analytical standard of 4-Hydroxy-1H-indole-3-carbaldehyde (HY-W091541). This product is intended for research and analytical applications. 4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .
|
-
- HY-101937C
-
|
|
Fluorescent Dye
|
Others
|
|
(±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
|
-
- HY-101937A
-
|
|
Fluorescent Dye
|
Others
|
|
(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
|
-
- HY-100335
-
|
|
Fluorescent Dye
Btk
|
Cancer
|
|
PCI-33380 is a fluorescent probe ( (Ex=532 nm, Em=555 nm). PCI-33380 consists of a (BTK) inhibitor PCI-32765 (HY-10997) attaching with a Bodipy-FL fluorophore via a piperazine linker. PCI-33380 binds predominantly to Btk in B cell lysates with cell permeable activity. PCI-33380 can be used for imaging live cancer cells such as non-Hodgkin lymphoma research
|
-
- HY-D3152
-
|
|
Fluorescent Dye
|
Others
|
|
NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
|
-
- HY-D1707
-
|
|
Fluorescent Dye
|
Others
|
|
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .
|
-
- HY-D1892
-
|
|
Fluorescent Dye
|
Others
|
|
6-Hexachloro-fluorescein phosphoramidite is a fluorescent probe that can be used for oligonucleotide labeling .
|
-
- HY-W127843
-
|
|
Fluorescent Dye
|
Others
|
|
Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg 2+ detection .
|
-
- HY-135639
-
|
|
Fluorescent Dye
|
Others
|
|
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-112636
-
|
|
Amyloid-β
|
Others
|
|
Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice .
|
-
- HY-D1090
-
|
|
DNA Stain
Fluorescent Dye
|
Others
|
|
JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .
|
-
- HY-W321446
-
|
|
Fluorescent Dye
|
Others
|
|
Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change .
|
-
- HY-D1470
-
|
|
Fluorescent Dye
|
Others
|
|
BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe .
|
-
- HY-D0993
-
|
Nonylacridine orange
|
Fluorescent Dye
|
Others
|
|
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
|
-
- HY-175131
-
|
|
Fluorescent Dye
|
Others
|
|
Prostaglandin D2-biotin is a fluorescent probe that can be used for detecting PGD2.
|
-
- HY-D1117
-
|
NADA hydrochloride
|
Fluorescent Dye
|
Infection
|
|
NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation .
|
-
- HY-W127775
-
-
- HY-D2133
-
|
Alendronate-Cy5
|
Fluorescent Dye
|
Others
|
|
Cy5-ALN (Alendronate-Cy5) is a fluorescently labeled bisphosphonate probe .
|
-
- HY-D0149
-
|
|
Cytochrome P450
|
Others
|
|
4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes .
|
-
- HY-DY1021
-
|
|
Fluorescent Dye
|
Others
|
DiSC3 (5) (solution) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3 (5) is up to 622/670 nm. DiSC3 (5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC50 value is 8 μM. DiSC3 (5) in the presence of Na +/K +-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .
Solvent and concentration: DMSO: 1 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-W800698
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 Alkyne is a green-fluorescent alkyne-activated probe routinely used for imaging of moderate to high abundance azide-containing biomolecules. BP Fluor 430 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near 430 nm. This probe is water-soluble and its fluorescence is pH independent over a wide pH range.
|
-
- HY-D1022A
-
|
Biotin-16-deoxyuridine-5'-triphosphate trisodium
|
DNA Stain
|
Others
|
|
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-D1022
-
|
Biotin-16-deoxyuridine-5'-triphosphate
|
Fluorescent Dye
|
Others
|
|
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-D2930
-
|
SNAP-SS-SulfoCy5
|
Fluorescent Dye
|
Others
|
|
BG-SS-SulfoCy5 (SNAP-SS-SulfoCy5) is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond. BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .
|
-
- HY-B1422S
-
|
Aminacrine-13C6
|
Bacterial
HIV
Isotope-Labeled Compounds
|
Infection
|
|
9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
- HY-D2379
-
|
|
Fluorescent Dye
|
Endocrinology
Cancer
|
HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .
|
-
- HY-D1752
-
|
D-22421
|
Fluorescent Dye
|
Others
|
|
JC-9 (D-22421) is a green-fluorescent probe used for ratiometric calculation of mitochondrial membrane potential.
|
-
- HY-D1089
-
|
|
Fluorescent Dye
|
Others
|
|
6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .
|
-
- HY-D1751
-
|
|
Fluorescent Dye
PKC
|
Others
|
|
RIM-1 is a fluorescent probe for protein kinase C (PKC) that can be used to visualize the distribution of PKC in cells.
|
-
- HY-135634
-
|
|
Fluorescent Dye
|
Others
|
|
GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-D2022
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 is a new type of hydrophilic fluorescent probe with strong stability and maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-104058
-
|
Green 488 BAPTA 1AM
|
Fluorescent Dye
|
Others
|
|
BAPTA Green 1AM (Oregon Green 488 BAPTA 1AM) is a fluorescent Ca 2+ indicator that consists of a green fluorescent probe OG 488 and a cell-permeable Ca 2+ chelator BAPTA AM.
|
-
- HY-D2290
-
|
|
Fluorescent Dye
|
Others
|
|
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
|
-
- HY-130025
-
HKOCl-3
2 Publications Verification
|
Fluorescent Dye
|
Others
|
|
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm .
|
-
- HY-D2287
-
|
|
Fluorescent Dye
|
Others
|
|
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
-
- HY-D0786
-
|
|
Fluorescent Dye
|
Others
|
|
3-Morpholinobenzanthrone is a fluorescent membrane probe, possessing higher dipole moment values in the excited-state than in the ground-state .
|
-
- HY-D2287A
-
|
|
Fluorescent Dye
|
Others
|
|
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
-
- HY-108715
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
|
-
- HY-D1158
-
-
- HY-D1765
-
|
|
Fluorescent Dye
|
Others
|
|
FM 1-43FX is a fluorescent membrane probe that contains an aliphatic amine which can react with aldehyde-based fixatives.
|
-
- HY-100335R
-
|
|
Fluorescent Dye
Reference Standards
Btk
|
Cancer
|
|
PCI-33380 (Standard) is the analytical standard of PCI-33380 (HY-100335). This product is intended for research and analytical applications. PCI-33380 is a fluorescent probe ( (Ex=532 nm, Em=555 nm). PCI-33380 consists of a (BTK) inhibitor PCI-32765 (HY-10997) attaching with a Bodipy-FL fluorophore via a piperazine linker. PCI-33380 binds predominantly to Btk in B cell lysates with cell permeable activity. PCI-33380 can be used for imaging live cancer cells such as non-Hodgkin lymphoma research
|
-
- HY-D2775
-
|
|
Fluorescent Dye
|
Others
|
|
Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co 2+ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co 2+ in the presence of other metal ions (Ex: 380 nm) .
|
-
- HY-D1518
-
-
- HY-D0938
-
|
CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
|
Fluorescent Dye
|
Others
|
|
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
-
- HY-D0251
-
|
Uranine
|
Fluorescent Dye
|
Cancer
|
|
Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
|
-
- HY-D0099
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
|
-
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dye
|
Others
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
-
- HY-141646
-
|
|
Fluorescent Dye
|
Others
|
|
MIT-PZR is a mitochondria-targeted,? low cytotoxicity fluorescent probe that can be used in live cells and in vivo imaging. Ex / Em = 485 / 705 nm
|
-
- HY-DY1078
-
|
|
Fluorescent Dye
|
Others
|
Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
Solvent and concentration: DMSO: 10 mM
|
-
- HY-103469
-
|
PO1
|
Fluorescent Dye
|
Others
|
|
Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye .
|
-
- HY-N7131
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
|
-
- HY-W800696
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 Azide is a water-soluble, green-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
BP Fluor 430 is a bright, photostable, green-fluorescent probe with excitation near its absorption maximum at 432 nm and emission maximum at 539 nm. This probe is water soluble and pH-insensitive from pH 4 to pH 10.
A next generation probe, BP Fluor 430 Picolyl Azide, is also available for detection of low abundance alkyne-tagged biomolecules.
|
-
- HY-135635
-
|
|
Fluorescent Dye
|
Others
|
|
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-D1377
-
|
|
Fluorescent Dye
|
Others
|
|
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .
|
-
- HY-D2327
-
|
|
Dipeptidyl Peptidase
|
Others
|
|
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively) .
|
-
- HY-D2315
-
|
|
Fluorescent Dye
|
Cancer
|
|
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
|
-
- HY-102055
-
|
|
JAK
|
Others
|
|
JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd value of 0.2 μM .
|
-
- HY-D1255
-
|
|
Fluorescent Dye
|
Cancer
|
|
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells .
|
-
- HY-157036
-
|
|
Fluorescent Dye
|
Others
|
|
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .
|
-
- HY-D2479
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO −) in living cells .
|
-
- HY-116215
-
|
|
Fluorescent Dye
|
Others
|
|
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
|
-
- HY-D2289
-
|
|
Fluorescent Dye
|
Others
|
|
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .
|
-
- HY-U00451
-
|
|
Fluorescent Dye
|
Others
|
|
ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).
|
-
- HY-D1759
-
|
|
Fluorescent Dye
|
Others
|
|
Fura-4F AM is a cell-permeant fluorescent calcium indicator. Upon entering the cell, this probe is hydrolyzed by cytosilic esterases and trapped as the active chelator.
|
-
- HY-130013
-
|
|
Fluorescent Dye
|
Others
|
|
HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .
|
-
- HY-D2288
-
|
|
Fluorescent Dye
|
Others
|
|
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .
|
-
- HY-D2762
-
|
|
Fluorescent Dye
|
Cancer
|
|
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
|
-
- HY-D0127
-
|
|
Fluorescent Dye
|
Others
|
|
Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm) .
|
-
- HY-D1883B
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D1457
-
|
|
Fluorescent Dye
|
Others
|
|
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
|
-
- HY-D1266
-
|
NO-red
|
Fluorescent Dye
|
Others
|
|
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
|
-
- HY-D2274
-
|
|
Fluorescent Dye
|
Others
|
|
EZH2-AF647 is a fluorescent probe derived from UNC2239 that improves receptor TR-FRET properties by using Alexa 647 dye .
|
-
- HY-D1399
-
|
|
Fluorescent Dye
|
Others
|
|
Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.
|
-
- HY-D1623
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 carboxylic acid chloride is a non-toxic red fluorescent dye with good solubility in organic solvents. Cyanine3 carboxylic acid chloride can be used as a non-reactive fluorophore for experimental control and calibration. Cyanine3 carboxylic acid chloride can also be synthesized with targeted agents as fluorescent probes for rapid detection of agent reactions .
|
-
- HY-D2525
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG-DMPE is a fluorescent probe that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and DMPE (HY-142983). Cy3-PEG-DMPE is widely used in biomolecule labeling, cell imaging and liposome research.
|
-
- HY-D2970
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression .
|
-
- HY-W012642
-
|
|
DNA Stain
|
Others
|
|
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics .
|
-
- HY-D0140
-
|
ETH 5294
|
Fluorescent Dye
|
Others
|
|
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .
|
-
- HY-D1683
-
NBD-PE
2 Publications Verification
|
Fluorescent Dye
|
Others
|
|
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .
|
-
- HY-D1148
-
|
|
Fluorescent Dye
|
Others
|
|
HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO - in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
|
-
- HY-144603
-
-
- HY-D1781
-
|
|
Fluorescent Dye
|
Others
|
|
NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis .
|
-
- HY-D1159
-
|
|
Reactive Oxygen Species (ROS)
Fluorescent Dye
|
Others
|
|
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
|
-
- HY-103684
-
|
Real Thiol-NH2
|
Fluorescent Dye
|
Neurological Disease
|
|
RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
|
-
- HY-101859
-
NucPE1
5 Publications Verification
Nuc-H2O2 Probe
|
Reactive Oxygen Species (ROS)
|
Others
|
|
NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
|
-
- HY-D0251R
-
|
Uranine (Standard)
|
Fluorescent Dye
Reference Standards
|
Cancer
|
|
Fluorescein (Standard) is the analytical standard of Fluorescein. This product is intended for research and analytical applications. Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
|
-
- HY-128868G
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Dextran (MW 150000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). FITC-Dextran (MW 150000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 150000) can be used in perfusion studies in animals or in fluorescence microlymphography, to study processes that affect the permeability of the blood brain barrier (BBB) . FITC-Dextran (MW 150000) can be used as fluorescent probe to study cell permeability .
|
-
- HY-DY1019
-
|
|
Fluorescent Dye
|
Others
|
2-NBDG (solution) is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
Solvent and Concentration: Sterile PBS: 5 mM
|
-
- HY-158779
-
|
SSP4
|
Fluorescent Dye
|
Others
|
|
Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe 2+, Fe 3+, Mg 2+, Ca 2+, and Zn 2+) .
|
-
- HY-D1257
-
|
Msr-green
|
Fluorescent Dye
|
Others
|
|
Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (λex=375 nm, λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells .
|
-
- HY-W248119
-
|
|
Fluorescent Dye
|
Others
|
|
8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY is a BODIPY derivative that can be used as a fluorescent probe for GFP-labeled muscarinic M1 receptor .
|
-
- HY-D1157
-
|
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
|
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
|
-
- HY-149835
-
|
|
Fluorescent Dye
|
Others
|
|
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
|
-
- HY-D1493
-
|
|
PKC
|
Others
|
|
FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor .
|
-
- HY-D3003
-
|
|
Fluorescent Dye
|
Others
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|
M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F₆₅₀/F₅₆₀) within the range of 0-40 μM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases .
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-
- HY-D2878
-
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Fluorescent Dye
Ferroptosis
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Others
|
|
MitoPeDPP is a mitochondrial-targeted fluorescent probe that is sensitive to LPO. MitoPeDPP is synthesized from diphenylpyrenephosphine. MitoPeDPP can be used to study the occurrence of mitochondrial LPO in RSL3-induced oligodendrocyte ferroptosis .
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-
- HY-D0029
-
|
5(6)-AFM; Fluoresceinamine mixed isomers
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Fluorescent Dye
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Others
|
|
5(6)-Aminofluorescein (5(6)-AFM) is an amino-containing fluorescein dye primarily used for biomolecular labeling, fluorescence imaging, and as a precursor for the synthesis of fluorescent probes (Ex/Em = 495/515 nm).
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- HY-D1526
-
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Fluorescent Dye
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Others
|
|
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
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-
- HY-112526
-
|
|
Fluorescent Dye
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Others
|
|
Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .
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-
- HY-W800692
-
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Fluorescent Dye
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Others
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|
BP Fluor 350 Azide is a blue-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets.
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-
- HY-151536
-
-
- HY-D1244
-
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|
Fluorescent Dye
|
Cardiovascular Disease
Inflammation/Immunology
|
|
CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd 2+ to Pd 0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer .
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-
- HY-D1570
-
|
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Fluorescent Dye
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Others
|
|
BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
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-
- HY-D0027R
-
|
Coumarin 120 (Standard); AMC (Standard)
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Fluorescent Dye
Antibiotic
Fungal
Reference Standards
|
Infection
|
|
7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
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-
- HY-W074143
-
|
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Fluorescent Dye
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Others
|
|
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
|
-
- HY-W040143
-
-
- HY-D1106
-
|
|
Fluorescent Dye
|
Cancer
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
-
- HY-D0027
-
|
Coumarin 120; AMC
|
Fluorescent Dye
Antibiotic
Fungal
|
Infection
|
|
7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
|
-
- HY-W011664
-
|
DPBF
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
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Others
|
|
1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
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-
- HY-135636
-
|
|
Fluorescent Dye
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Others
|
|
Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2119
-
CQ-Lyso
2 Publications Verification
|
Fluorescent Dye
|
Cancer
|
|
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .
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-
- HY-D1093
-
|
|
Fluorescent Dye
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Others
|
|
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
|
-
- HY-D3157
-
|
|
Fluorescent Dye
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Others
|
|
Photoactive esterase probe is a photoactivatable fluorescent probe for esterase. Photoactive esterase probe is used for the detection and imaging of esterase activity in living cells .
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-
- HY-D2266
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
FluoBar1 is an imaging fluorescence probe modified by a barbiturate ligand with fluorescent coumarin. FluoBar1 can monitor L-type voltage-gated calcium channels (LTCC) in living cells in real time for the study of neurological diseases .
|
-
- HY-118213
-
|
|
Fluorescent Dye
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Others
|
|
N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
|
-
- HY-N7131R
-
|
|
Fluorescent Dye
Reference Standards
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Others
|
|
Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
|
-
- HY-101859R
-
|
Nuc-H2O2 Probe (Standard)
|
Reference Standards
Reactive Oxygen Species (ROS)
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Others
|
|
NucPE1 (Standard) (Nuc-H2O2 Probe (Standard)) is the analytical standard of NucPE1 (HY-101859). This product is intended for research and analytical applications. NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
|
-
- HY-139816
-
-
- HY-D1256
-
|
|
Fluorescent Dye
|
Neurological Disease
Metabolic Disease
|
|
Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .
|
-
- HY-D2756
-
|
|
Fluorescent Dye
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Others
|
|
OG 488 alkyne is a bright, green-fluorescent alkyne-activated probe routinely used for imaging of azide-containing biomolecules. OG 488 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
|
-
- HY-D1443
-
|
(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
|
Amyloid-β
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Others
|
|
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
|
-
- HY-D0921
-
|
ADS 815EI
|
Fluorescent Dye
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Others
|
|
Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
|
-
- HY-133705
-
|
|
HSP
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Others
|
|
Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90 (Ex/Em = 488/515 nm) .
|
-
- HY-D3404
-
|
|
DNA Stain
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Others
|
|
BODi-1 is a fluorescent modulator targeting dsDNA, which binds to dsDNA via a bis-intercalation mechanism (Ex=465 nm, Em=490 nm). BODi-1 exhibits a fluorescence enhancement effect upon binding to nucleic acids, but its fluorescence intensity, anisotropy and average lifetime decrease at higher dye/DNA ratios. When BODi-1 binds to DNA in liposome complexes, it also shows red-shifted emission spectra, along with reduced quantum yield and average lifetime. BODi-1 does not induce significant DNA conformational changes when the dye/DNA ratio is below 0.01. BODi-1 can be used as a fluorescent probe for the characterization of liposome complexes and FRET studies at this ratio .
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-
- HY-DY1102
-
|
|
Fluorescent Dye
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Others
|
BODIPY FL-C16 (solution) is a BODIPY-labeled analog of Palmitic acid (HY-N0830), which serves as a fluorescent lipid tracer. BODIPY FL-C16 (solution) also acts as a ligand for liver fatty acid-binding protein (L-FABP) and intestinal fatty acid-binding protein (I-FABP) , with Kd values of 270 nM and 330 nM, respectively. BODIPY FL-C16 (solution) is rapidly taken up by cells, and after metabolic conversion to phospholipids, it is incorporated into the membrane structures of intracellular organelles and extracellular vesicles .
Solvent and concentration: DMSO: 5 mM
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-
- HY-113285F
-
|
|
Biochemical Assay Reagents
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Others
|
|
FITC-Ureidopropionic acid is labeled with FITC fluorescent label on Ureidopropionic acid. FITC-Ureidopropionic acid is a fluorescent probe used to label biomolecules or cells.
|
-
- HY-151704
-
|
|
Fluorescent Dye
|
Cancer
|
|
ICG-alkyne is a short-wave infrared (SWIR)-emitting cyanine fluorescent probe based on alkyne-derivatized indocyanine green. ICG-alkyne can undergo click chemistry reaction to conjugate with antibody molecules via binding to the azide groups introduced into antibodies. ICG-alkyne enables SWIR fluorescent molecular imaging of breast tumors in living mice. ICG-alkyne can be used in breast cancer-related research .
|
-
- HY-D1745
-
|
fac-[Re(CO)3(phen)L]
|
Fluorescent Dye
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Others
|
|
Liptracker-green (fac-[Re(CO)3(phen)L]) is a cell-permeable fluorogenic probe that localizes to polar lipids, and can be used to label lipid droplets and other high lipid-content compartments in live and fixed cells using fluorescent microscopy.
|
-
- HY-15942
-
5-TAMRA
3 Publications Verification
|
Fluorescent Dye
|
Others
|
|
5-TAMRA can produce bright, pH-insensitive orange-red fluorescence (excitation and emission extremes of 546/579) and has good photostability. 5-TAMRA is mainly used as a fluorescent marker for the synthesis and study of specific oligonucleotide probes .
|
-
- HY-W800704
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 594 alkyne is a bright, red-fluorescent alkyne-activated probe routinely used for imaging of azide-containing biomolecules. BP Fluor 594 alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
|
-
- HY-126793
-
|
DCFH2-DA
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
|
2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon .
|
-
- HY-W013435
-
|
|
Fluorescent Dye
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Others
|
|
1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic nitric oxide (NO) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO .
|
-
- HY-D1877
-
|
|
Pyruvate Kinase
|
Others
|
|
ZY-1 is a control molecule of ZY-2 (HY-D1876, a PKM2 fluorescent probe). ZY-1 shows a low fluorescence emission in HeLa, a cervical cancer cell abundant in PKM2 expression .
|
-
- HY-108715R
-
|
|
Fluorescent Dye
Reference Standards
|
Neurological Disease
|
|
Real Thiol (Standard) is the analytical standard of Real Thiol (HY-108715). This product is intended for research and analytical applications. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
|
-
- HY-D1264
-
|
Zn-green
|
Fluorescent Dye
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Others
|
|
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn 2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn 2+ in living cells .
|
-
- HY-D3319
-
|
|
Biochemical Assay Reagents
MMP
|
Inflammation/Immunology
Cancer
|
|
BHQ‑3 carboxylic acid is an azo‑containing dark fluorescence quencher. BHQ‑3 carboxylic acid is conjugated to an MMP‑cleavable peptide and paired with a fluorophore to form an activatable probe for MMP activity detection in vitro. BHQ‑3 carboxylic acid shows maximal absorption in the 620 to 730 nm range. BHQ‑3 carboxylic acid–based fluorescent probes can be used in the research of arthritis and tumor‑related pathological processes. .
|
-
- HY-D3392
-
|
|
Fluorescent Dye
Ligands for E3 Ligase
|
Others
|
|
Thalidomide-cyanine 5 is a fluorescent probe prepared by conjugating the CRBN binder Thalidomide (HY-14658) with the near-infrared fluorescent dye Cy5. Thalidomide-cyanine 5 binds to DDB1-CRBN protein complex with a Kd of 121.6 nM. Thalidomide-cyanine 5 binds to CRBN to form a binary complex, and is mainly used for the visual tracking research of degradants such as PROTAC (Ex/Em = 650/665 nm) .
|
-
- HY-D1617
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
|
-
- HY-D1378
-
|
|
Fluorescent Dye
|
Others
|
|
C-Laurdan is a modified Laurdan (HY-D0080) probe that imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan can be used in research of lipid arrangement and fluidity in biological membranes or artificial lipid membranes .
|
-
- HY-D2297
-
|
|
Fluorescent Dye
|
Others
|
|
AIE-GA is a Golgi apparatus (GA) fluorescent probe (green channel: λex = 405 nm, λem = 500-700 nm). AIE-GA has a favourable binding ability to interact with COX-2. AIE-GA binds to the cyclooxygenase catalytic site of COX-2 .
|
-
- HY-D2345
-
|
|
Fluorescent Dye
Carbonic Anhydrase
|
Cancer
|
|
GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors .
|
-
- HY-151644
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein hydrazide is a sensitive fluorescent probe for Hg 2+ and Co 2+ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM [2][3].
|
-
- HY-D0154
-
|
Tetramethylrhodamine-6-isothiocyanate
|
Fluorescent Dye
|
Others
|
|
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .
|
-
- HY-D1055
-
|
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
Mitochondrial Metabolism
|
Cancer
|
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.
Excitation/emission wavelength: 510/580 nm.
|
-
- HY-D1876
-
|
|
Fluorescent Dye
|
Cancer
|
|
ZY-2 is a specific fluorescent probe for pyruvate kinase M2 (PKM2). ZY-2 can image in PKM2-positive cells in a time- and concentration-dependent manner. ZY-2 can be used for the detection of cancer cells .
|
-
- HY-DY1048
-
|
|
Fluorescent Dye
|
Cancer
|
DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-D0943
-
|
Kernechtrot
|
Fluorescent Dye
Photosensitizer
|
Others
|
|
Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium . Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine .
|
-
- HY-D0090
-
|
|
Fluorescent Dye
|
Others
|
|
MQAE is a chloride ion (Cl -) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) .
|
-
- HY-D1756
-
|
|
Fluorescent Dye
|
Others
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
-
- HY-D2299
-
|
|
Fluorescent Dye
|
Metabolic Disease
Cancer
|
|
AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum .
|
-
- HY-D0267
-
|
|
Fluorescent Dye
|
Others
|
|
Quinaldine red is a fluorescent probe for determining the melting temperature (Tm) of proteins .
|
-
- HY-D2755
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 650 carboxylic acid is an vibrant far-red fluorochrome with comparable or improved performance over other dyes, including BP Fluor 647 and Cy5 dye, for fluorescent applications. It is used to label antibodies and other proteins as molecular probes for cellular imaging and other fluorescence detection methods application.
|
-
- HY-D0816
-
|
RH-123; R-22420
|
Fluorescent Dye
|
Cardiovascular Disease
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-D0984
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-101876
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-D0984A
-
|
T668
|
Fluorescent Dye
|
Others
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-DY1044
-
|
|
Bacterial
|
Infection
|
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
Solvent and concentration: DMSO: 50 mM
|
-
- HY-D0985A
-
|
Tetramethylrhodamine ethyl ester perchlorate
|
Fluorescent Dye
|
Others
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-D0309
-
|
Basic Red 1
|
Environmental Pollutants
Fluorescent Dye
|
Cancer
|
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
|
-
- HY-D1412
-
|
|
Ferroptosis
|
Others
|
|
LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .
|
-
- HY-147532
-
|
|
Cannabinoid Receptor
|
Cancer
|
|
CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells .
|
-
- HY-D0151
-
|
|
Fluorescent Dye
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Others
|
|
Tetramethylrhodamine-5-maleimide is a fluorescent probe with high specificity for cysteine thiol (SH) groups. Tetramethylrhodamine-5-maleimide has high sensitivity, responds rapidly to negatively charged nanoparticles, and shows a concentration-dependent decrease in fluorescence intensity, but it is susceptible to interference from humic acids .
|
-
- HY-D1428
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
Di-4-ANEPPDHQ is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].
|
-
- HY-D1532
-
|
|
Parasite
|
Others
|
|
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite .
|
-
- HY-D1625
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction . Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-DY1089
-
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|
Fluorescent Dye
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Others
|
Di-4-ANEPPDHQ (solution) is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].
Solvent and concentration: DMSO: 5 mM
|
-
- HY-D2201
-
|
|
Fluorescent Dye
|
Cancer
|
|
Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .
|
-
- HY-W127703
-
|
|
Fluorescent Dye
Biochemical Assay Reagents
|
Others
|
|
Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
|
-
- HY-D2279
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
|
-
- HY-D2477
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
|
-
- HY-D2616
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG2000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG2000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
|
-
- HY-D1631
-
-
- HY-150978
-
|
|
Fluorescent Dye
|
Others
|
|
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
|
-
- HY-D2617
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG5000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG5000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
|
-
- HY-155698
-
|
|
Fluorescent Dye
CXCR
|
Others
|
|
Mz438 is high-affinity and selective fluorescent CXCR2 ligand. Mz438 is a small-molecule-based fluorescent probe targeting the IABS of CXCR2 .
|
-
- HY-136870
-
|
|
Fluorescent Dye
|
Others
|
|
Kyoto probe 1 is a hiPSCs fluorescent probe. Kyoto probe 1 selectively labels human pluripotent stem cells. Kyoto probe 1 is primarily explained by the distinct expression patterns of ATP-binding cassette (ABC) transporters by hiPS cells and differentiated cells .
|
-
- HY-D3447
-
|
|
Fluorescent Dye
Ferroptosis
|
Others
|
|
LPd peroxida probe-2 (Compound I-1) is a lipid peroxidation fluorescent indicator (Ex = 488 nm, Em = 535 nm). LPd peroxida probe-2 undergoes fluorescence spectral changes in response to lipid hydroperoxides and can be used for Ferroptosis detection and cell imaging.
|
-
- HY-DY1023
-
|
|
Fluorescent Dye
|
Others
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D1275
-
|
|
Fluorescent Dye
|
Others
|
|
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
|
-
- HY-DY1042
-
|
|
Fluorescent Dye
|
Others
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-15940
-
|
5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
|
Fluorescent Dye
|
Cancer
|
|
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
|
-
- HY-DY1054
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
|
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 5 mM
|
-
- HY-D1156
-
|
|
Reactive Oxygen Species (ROS)
Fluorescent Dye
|
Others
|
HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
- HY-D2286
-
|
|
Fluorescent Dye
|
Others
|
|
HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
|
-
- HY-D0986
-
|
|
Fluorescent Dye
|
Others
|
|
TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
|
-
- HY-D1156A
-
|
|
Reactive Oxygen Species (ROS)
Fluorescent Dye
|
Others
|
HKSOX-1m (5/6-mixture) hydrobromide is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
|
-
- HY-133876
-
|
DiA
|
Fluorescent Dye
|
Others
|
|
4-Di-16-ASP is a green fluorescent membrane dye. 4-Di-16-ASP is a lipophilic aminostyryl probe with a broad emission spectrum (can be detected with green, orange or even red filters). It is commonly used for neuronal membrane tracing (it diffuses faster than DiO) .
|
-
- HY-117401
-
|
|
Fluorescent Dye
|
Others
|
|
5-Dodecanoylaminofluorescein is an amphipathic (amphoteric) fluorescent probe (Ex/Em = 485 nm/515-535 nm), which consists of a hydrophilic fluorescein core and a hydrophobic dodecanoyl group (C12 fatty acid chain) linked by an amide bond. 5-Dodecanoylaminofluorescein is mainly used as an interface-localized radical trapping/indicator probe. Dodecanoylaminofluorescein can be used for the determination of the antioxidant properties of emulsions, or can serve as a lipophilic drug model for the study of passive skin penetration when encapsulated in tyrosine-derived nanospheres .
|
-
- HY-DY1053
-
|
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
1,3-Diphenylisobenzofuran (DPBF) (solution) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-W800838
-
|
|
Fluorescent Dye
|
Cancer
|
|
BP Fluor 488 Tetrazine is a bright, green-fluorescent probe used for detection TCO-tagged biopolymers. BP Fluor 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre?targeted cell labeling studies where rapid reaction kinetics is a must BP Fluor 488 Tetrazine probe would of great value.
|
-
- HY-17672
-
|
|
Drug Derivative
|
Cancer
|
|
Jasplakinolide probe-1 (Compound 12), a Jasplakinolide (HY-P0027) derivative, is a Jasplakinolide probe. Jasplakinolide probe-1 shows anti-proliferative activity and can inhibit the dynamics of actin, cause the collapse of cell lamellipodia, interfering with the dynamic balance of actin. Jasplakinolide probe-1 can be used for imaging of actin structure in cells conjugated with a fluorescent dye .
|
-
- HY-160250
-
|
|
Fluorescent Dye
UGT
|
Metabolic Disease
|
|
UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
|
-
- HY-18675
-
|
|
Fluorescent Dye
|
Others
|
|
IQ-R is a novel hypoxia-sensitive fluorescent probe, consisting of an indolequinone unit and a rhodol fluorophore.
|
-
- HY-119395
-
-
- HY-119395B
-
-
- HY-D1253
-
|
|
TrxR
|
Neurological Disease
|
|
TP-TRFS is a highly selective and the first two-photon fluorescent probe of thioredoxin reductase (TrxR) .
|
-
- HY-D1395
-
-
- HY-D1393
-
|
Pb:Ag2Se
|
Fluorescent Dye
|
Others
|
|
Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
|
-
- HY-D3193
-
|
|
Fluorescent Dye
|
Others
|
|
CDg4 is a green fluorescent probe and member of the fluorescent diamino-chalcone library.CDg4 binds to glycogen on mouse embryonic stem cell colony surfaces .
|
-
- HY-D1735
-
|
Golgi-Red Tracke
|
Fluorescent Dye
|
Others
|
|
The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. BODIPY TR Ceramide (Golgi-Red Tracke) is a Golgi-specific fluorescent dye, which can visualise individual cells . Ex/Em=589 nm/616 nm.
|
-
- HY-D1612
-
|
|
Fluorescent Dye
|
Others
|
|
The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye . BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells . Ex/Em= 505 nm/512 nm.
|
-
- HY-D1259
-
|
VDP-green (NEP)
|
Fluorescent Dye
|
Neurological Disease
|
|
NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm). NEP has the potential for parkinsonism .
|
-
- HY-D2285
-
|
|
Fluorescent Dye
|
Cancer
|
|
MOR-CES2 is a near-infrared fluorescent probe (Ex= 630 nm, Em=735 nm) capable of identifying cancer cells and tissues, as well as exhibiting a sensitive response to inflammation. MOR-CES2 holds potential as an efficient imaging tool in assisting surgical resection of CES2-related tumors .
|
-
- HY-DY1040
-
|
|
Fluorescent Dye
Biochemical Assay Reagents
|
Others
|
LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
Solvent and concentration: DMSO: 1 mM
|
-
- HY-103684R
-
|
Real Thiol-NH2 (Standard)
|
Fluorescent Dye
Reference Standards
|
Neurological Disease
|
|
RT-NH2 (Standard) is the analytical standard of RT-NH2 (HY-103684). This product is intended for research and analytical applications. RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
|
-
- HY-D2549
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2548
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-N15875
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
18:1-18:1-C11 BODIPY 505/515 TG is a fluorescently-labeled triglyceride that can be used as a fluorescent probe (Ex/Em = 495/503 nm).
|
-
- HY-D3008
-
-
- HY-150087
-
|
|
Fluorescent Dye
|
Others
|
|
Ctrl-CF4-S2 is a chemically modified control probe of the copper probe Copper Fluor-4 (CF4, HY-150086), in which two of the four thioether ligands in CF4 (HY-150086) are replaced with methylene groups. CF4 (HY-150086) is a fluorescent probe used for detecting the presence and distribution of copper ions, whereas Ctrl-CF4-S2 does not respond to copper ions. This allows it to eliminate background signals from copper, thereby helping to determine whether the signals from CF4 (HY-150086) accurately reflect the dynamic changes of copper ions in biological systems
|
-
- HY-D1719
-
Cypate
1 Publications Verification
|
Fluorescent Dye
|
Others
|
|
Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .
|
-
- HY-D3381
-
|
|
Fluorescent Dye
|
Others
|
|
MitoCLox is a mitochondria-targeted ratiometric fluorescent probe for measuring mitochondrial inner membrane lipid peroxidation .
|
-
- HY-D3240
-
|
|
Fluorescent Dye
|
Others
|
|
Photoactive NTR probe (Compound 1) is a covalent crosslinker and Fluorescent indicator targeting Nitroreductase. The Photoactive NTR probe undergoes a sequential activation process: it is first activated via nitroreductase-mediated nitro-to-amino conversion, and then forms a fluorescent product upon photoactivation. The Photoactive NTR probe can form covalent adducts with the side chains of cysteine, tyrosine, lysine and histidine in adjacent proteins to reduce fluorophore diffusion. The Photoactive NTR probe enables super-resolution (STORM) imaging of active mitochondrial nitroreductase microdomains in living cells .
|
-
- HY-143218
-
|
Tetraphenylethene maleimide
|
Huntingtin
Parasite
|
Infection
Neurological Disease
|
|
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .
|
-
- HY-DY1024
-
|
|
Huntingtin
Parasite
|
Infection
Neurological Disease
|
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2522
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG5000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W856375
-
|
|
MOFs
Fluorescent Dye
|
Others
|
|
(E)-BSPOTPE is the E configuration of BSPOTPE (HY-W856375A). BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
|
-
- HY-D1296
-
|
|
Fluorescent Dye
|
Others
|
|
Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
|
-
- HY-D2521
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG2000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-129420
-
|
|
Fluorescent Dye
|
Cancer
|
|
WSP-5 is a H2S-selective fluorescent probe (Ex/Em = 502/525 nm). WSP-5 enables visual monitoring of H2S released and accumulated from peptide-H2S donor conjugates in glioma cells. WSP-5 is applicable to glioma research .
|
-
- HY-D2004
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
ATTO 488 streptavidin is a fluorescent reagent that specifically targets and binds to biotin (biotin), formed by the conjugation of ATTO 488 with streptavidin (HY-P3152). ATTO 488 streptavidin enables visualization of the activity of streptavidin immobilized on the surface of polymeric nanoparticles, or acts as a fluorescent probe to detect the selective binding and internalization process of anti-HB-EGF/NA with cells expressing HB-EGF (with no such effect on cells that do not express this receptor). ATTO 488 streptavidin effectively verifies the function of streptavidin conjugated to the surface of nanoparticles and is suitable for research related to atherosclerotic cardiovascular diseases .
|
-
- HY-W015012
-
|
|
Fluorescent Dye
|
Others
|
|
NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
|
-
- HY-W002356
-
|
|
Drug Intermediate
|
Others
|
|
2-Pyridinecarbothioamide is a building block, that can be used for synthesis of Zn 2+ responsive fluorescent probe .
|
-
- HY-153902
-
|
|
STAT
Fluorescent Dye
|
Others
|
|
DG-8 is a potent inhibitor of STAT3-dependent transcription (IC50 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety .
|
-
- HY-D1671
-
|
|
Fluorescent Dye
|
Others
|
|
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .
|
-
- HY-D2572
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG5000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2571
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG2000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-DY1057
-
|
|
Fluorescent Dye
|
Others
|
TMA-DPH (solution) is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D1547
-
|
|
Fluorescent Dye
|
Others
|
|
1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea (compound 1a) can be used as a fast-responsive fluorescent gold ion probe for detection of gold ions in water and synthetic products .
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![1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea](//file.medchemexpress.com/product_pic/hy-d1547.gif)
- HY-W856375A
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Fluorescent Dye
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Others
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BSPOTPE is the mixture of (E)-BSPOTPE (HY-W856375) and (Z)-BSPOTPE. BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
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- HY-D1832
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VF 532 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1835
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VF 594 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 594 TSA (200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1833
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VF 680 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1831
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VF 620 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 620 TSA (200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D3004
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Fluorescent Dye
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Others
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GSH Tracker Probe (CPDSA) is a cyanine-based fluorescent probe with a NIR emission that is specific for GSH (excitation: 635 nm; emission: 655-755 nm). CPDSA can monitor and image GSH levels in live cells and in vivo .
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- HY-W800699
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Fluorescent Dye
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Others
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BP Fluor 430 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 430 DBCO is an ideal alternative to copper requiring fluorescent alkynes.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near its absorption maximum at 432 nm. Its emission peak at 539 nm is pH independent over a wide pH range.
BP Fluor DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.
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- HY-D2338
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Fluorescent Dye
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Others
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PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .
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- HY-159529
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DBCO-PEG4-Eosin Y
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Fluorescent Dye
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Others
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DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.
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- HY-DY1058
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Fluorescent Dye
Reactive Oxygen Species (ROS)
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Others
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2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) (solution) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D1258
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VDP-green
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Fluorescent Dye
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Others
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AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
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- HY-D0153
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Fluorescent Dye
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Cancer
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Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
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- HY-DY1082
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Fluorescent Dye
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Others
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Green DND-26 (solution) is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
Solvent and concentration: DMSO: 2 mM
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- HY-168322
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Fluorescent Dye
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Others
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2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe, that enters into oligodeoxyribonucleic acid as a nucleotide replacement. 2-Hydroxy nile red trifluoromethanesulfonate can be used as a DNA probe for detecting the polar changes in tumor microenvironments .
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- HY-D1464
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CH1055
1 Publications Verification
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Fluorescent Dye
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Cancer
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CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-125749
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Fluorescent Dye
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Others
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Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λex = 430 nm, λem = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes .
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- HY-134392A
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Nucleoside Antimetabolite/Analog
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Others
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6-Alkyne-NAD+ sodium is a nicotinamide adenine dinucleotide (NAD) analogue. 6-Alkyne-NAD+ sodium can be used as a fluorescent probe coupled with fluorescent labels for marking ADP-ribose polymerase substrate proteins .
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- HY-D1837
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VF 488 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 488 TSA（200×） (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1834
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VF 640 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 640 TSA（200×） (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1838
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VF 350 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 350 TSA（200×） (VF 350 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D3226
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Fluorescent Dye
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Neurological Disease
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Zinc (II) probe-1 (Compound DNP) is a dual-color Fluorescent probe that can simultaneously monitor Zn 2+ and H +. Upon interaction with Zn 2+, Zinc (II) probe-1 produces bright blue fluorescence (excitation wavelength: 405 nm; blue channel wavelength: 420-500 nm). Upon interaction with H +, Zinc (II) probe-1 exhibits red fluorescence (excitation wavelength: 561 nm; red channel emission wavelength: 630-730 nm). Zinc (II) probe-1 can be used in studies related to depression .
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- HY-W009253
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2,4,5-Triphenylimidazole
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Fluorescent Dye
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Others
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Lophine is a traditional chemiluminescent and fluorescent probe. Lophine and its derivatives are widely applied for reactive oxygen species (ROS) detection .
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- HY-D1663
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Fluorescent Dye
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Others
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APTAB is a fluorescent cationic membrane probe. APTAB locates the anthracene-labeled molecules incorporated into model membranes by fluorescence quenching .
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- HY-133884
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Fluorescent Dye
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Cancer
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ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye .
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- HY-D2944
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- HY-D3266
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Fluorescent Dye
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Cancer
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IR 650 DBCO is a far-red-fluorescent probe, pH-insensitive, azide-reactive probe routinely used for imaging of azide-containing biomolecules without the need for a copper catalyst. (Ex=651nm, Em=668 nm)
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- HY-D0309R
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Basic Red 1 (Standard)
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Fluorescent Dye
Reference Standards
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Cancer
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Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D1464A
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Fluorescent Dye
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Cancer
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CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-DY1009
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Fluorescent Dye
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Others
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CFDA-SE (solution) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
Solvent and concentration: DMSO: 5 mM
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- HY-D2344
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3-Benzothiazole-daphnetin
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Fluorescent Dye
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Others
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3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections .
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- HY-D2339
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Fluorescent Dye
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Others
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H-FluNox is a selective fluorescent probe that senses labile heme using biomimetic N-oxide deoxygenation to trigger fluorescence. H-FluNox is more than 100-fold selective for labile heme over Fe(II), enabling the discrimination of labile heme from labile Fe(II) pools in living cells. H-FluNox is sensitive enough to detect the subcellular labile heme. (λex=490 nm, λem=535 nm)
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- HY-D2769
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Difluorocarboxyfluorescein azide, 6-isomer
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Fluorescent Dye
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Others
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Oregon green 488 azide (Difluorocarboxyfluorescein azide, 6-isomer) is a bright green fluorescent azide-activated probe that reacts with terminal alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). Oregon green 488 azide can label goat anti-mouse IgG and exhibits excellent luminescence efficiency. Oregon green 488 azide, as a streptavidin conjugate, is used for flow cytometry staining of macrophages .
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- HY-D0129
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MPTS
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Fluorescent Dye
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Others
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8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe .
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- HY-D2945
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Fluorescent Dye
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Others
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CLIP-Biotin is a Biotin-labeled CLIP tag fluorescent probe. CLIP-Biotin can be used for marking the CLIP-tag fusion proteins in cells.
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- HY-141618
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Fluorescent Dye
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Others
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5(6)-Carboxyrhodamine 110 is an amine-reactive fluorescent probe for labeling DNA, cells and proteins (Ex/Em = 498/530 nm) .
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- HY-141511
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Fluorescent Dye
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Neurological Disease
Cancer
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Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
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- HY-D0040
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Fluorexon
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Fluorescent Dye
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Others
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Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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- HY-111330
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HPF; 3'-p-(Hydroxyphenyl) fluorescein
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Fluorescent Dye
Reactive Oxygen Species (ROS)
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Others
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Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
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- HY-128692
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Fluorescent Dye
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Neurological Disease
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Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-125452
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Fluorescent Dye
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Others
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DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
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- HY-W127715
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Fluorescent Dye
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Others
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Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-D3216
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Fluorescent Dye
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Others
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ER-Cu (II) is an endoplasmic reticulum-selective fluorescent Cu 2+ probe. ER-Cu (II) localizes specifically to the endoplasmic reticulum of hepatocytes .
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- HY-D2931
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Fluorescent Dye
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Others
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SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe, specifically designed for live-cell protein labeling and real-time imaging applications .
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- HY-D2951
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Fluorescent Dye
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Others
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BG-Kaede chromophore (Compound 4c) is a SNAP-tag-specific fluorescent probe, which is designed and synthesized using the chromophore of the red fluorescent protein Kaede as a template. BG-Kaede chromophore can be used as a tool for visualizing proteins in living cells .
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- HY-128868D
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Fluorescent Dye
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Others
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FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-128868A
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Fluorescent Dye
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Others
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FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-151708
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Fluorescent Dye
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Others
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CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2341
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Fluorescent Dye
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Cancer
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6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
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- HY-128868
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Fluorescent Dye
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Others
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FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-D2204
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Phosphatase
SHP1
Fluorescent Dye
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Cancer
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SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe 3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .
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- HY-D1094
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SNARF 1
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Fluorescent Dye
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Others
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Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH (Ex: 488 nm). Carboxy-SNARF 1 (5/6-mixture) can be used for measurement pH. Carboxy-SNARF 1 (5/6-mixture) exhibits a significant emission shift from yellow-orange (Em: 580 nm) to deep red fluorescence (Em: 640 nm) under acidic and basic conditions (pH=7-8), respectively .
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- HY-DY1087
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Fluorescent Dye
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Cancer
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Coppersensor 1 (solution) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
Solvent and concentration: DMSO: 2 mM
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- HY-163146
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Fluorescent Dye
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Cancer
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TME-HYM (PH Probe) is a novel fluorescent probe based on acidic tumor microenvironment (TME) activation and organic anion transporting polypeptide (OATPs, overexpressed on cancer cells), and can be selective uptaken. TME-HYM (PH Probe) can selectively lit up cancer cells and tumor tissues, offering dual tumor selectivity for precise visualization of tumor mass .
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- HY-W800697
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Fluorescent Dye
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Others
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BP Fluor 430 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site will dramatically increase the rate of CuAAC reaction without the need to increase concentration of azide reagent or copper.
In addition, the use of BP Fluor 430 Picolyl Azide instead of conventional BP Fluor 430 Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling.
In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
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- HY-W800693
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Fluorescent Dye
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Others
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BP Fluor 405 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site dramatically increases the rate of CuAAC reaction without increasing the concentrations of azide reagent or copper.
In addition, the use of picolyl azide instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling.
In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
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- HY-D0896
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ANS
1 Publications Verification
ANSA; 8-Anilino-1-naphthalenesulfonic acid
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Bacterial
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Infection
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ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×10 6 M -1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .
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- HY-D2959
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CLIP-DF
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Fluorescent Dye
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Others
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BC-DF is a diacetyl fluorescein labeled CLIP tag fluorescent probe. BC-DF can be used for labeling CLIP-tag fusion protein in cells .
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- HY-D2960
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CLIP-OG
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Fluorescent Dye
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Others
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BC-OG is an oregon green labeled CLIP tag fluorescent probe. BC-OG can be used for labeling CLIP-tag fusion protein in cells .
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- HY-169799
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CGamF
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Endogenous Metabolite
Fluorescent Dye
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Metabolic Disease
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Cholylglycylamidofluorescein (CGamF) is a fluorescent probe for hepatic bile acid transport. Cholylglycylamidofluorescein is composed of Cholic acid conjugated via a glycylamino linkage to fluorescein. (Ex/Em = 492/515 nM in Aqueous)
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- HY-W800701
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Biochemical Assay Reagents
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Others
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BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes.
BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.
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- HY-121462
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Quinoline Blue
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Fluorescent Dye
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Cancer
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Cyanine is an excellent fluorescent core scaffold for constructing fluorescent probes. Covalent conjugation of Cyanine with other potent compounds can not only enhance their efficacy but also expand their application modes. Cyanine supports the development of cancer theranostic agents. Cyanine can be used in cancer research .
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- HY-125385
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Endogenous Metabolite
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Metabolic Disease
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Sulforhodamine 101 DHPE is a fluorescent probe made from the conjugation of the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE to sulforhodamine 101, a red fluorescent dye that displays excitation/emission spectra of 586/605 nm, respectively. It integrates into phospholipid bilayers and has been used for imaging of solid supported lipid bilayers, detection of protein-ligand binding on bilayers, and to monitor colocalization of lipid probes in liposomes via resonance energy transfer (RET).
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-
- HY-100857
-
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Fluorescent Dye
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Neurological Disease
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|
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrP Sc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity .
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-
- HY-149931
-
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Fluorescent Dye
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Cancer
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|
BMV109 is a quenched probe that becomes fluorescent when cleaved and covalently bound by active cathepsin proteases. BMV109 can be exploited for tumor imaging .
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-
- HY-129097
-
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Fluorescent Dye
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Others
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|
FFN-102 trifluoroacetate is an analogue of biogenic neurotransmitters. FFN-102 trifluoroacetate is a pH-dependent fluorescent probe that labels dopamine cell bodies, axons, and presynaptic terminals .
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-
- HY-D3002
-
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Fluorescent Dye
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Metabolic Disease
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|
ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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-
- HY-D2413
-
|
BODIPY FL PEG4-VH032
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Fluorescent Dye
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Others
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|
BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a Kd value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .
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-
- HY-D1274
-
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Fluorescent Dye
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Inflammation/Immunology
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|
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D0989
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Fluorescent Dye
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Others
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|
Rhod-2 is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
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-
- HY-D1274B
-
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Fluorescent Dye
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Inflammation/Immunology
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Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-133821
-
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G-quadruplex
|
Neurological Disease
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|
N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
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-
- HY-DY1016
-
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|
Fluorescent Dye
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Others
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FITC-Dextran (MW 10000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
Solvent and Concentration: Sterile water: 2 mM
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-
- HY-D1274C
-
|
|
Fluorescent Dye
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Inflammation/Immunology
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|
Sulfo-cyanine3 azide potassium is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide potassium can be used for synthesis of fused tricyclic heterocycles, producing immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-DY1035
-
|
|
Reactive Oxygen Species (ROS)
Fluorescent Dye
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Others
|
Hydroxyphenyl Fluorescein (HPF) (solution) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
Solvent and concentration: DMSO: 10 mM
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-
- HY-DY1018
-
|
|
Fluorescent Dye
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Others
|
FITC-Dextran (MW 4000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
Solvent and Concentration: Sterile water: 2 mM
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-
- HY-D1274A
-
|
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Fluorescent Dye
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Others
|
|
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D3141
-
|
|
|
Cancer
|
|
DR probe is a "dual-key-and-lock" fluorescent probe designed based on the Resorufin (HY-123533) scaffold (Ex/Em = 647 nm/663-738 nm). DR probe can be sequentially activated by hydrogen peroxide to form the intermediate SR, which acts as a tyrosinase substrate to trigger a fluorescence turn-on signal. DR probe can distinguish normal melanocytes from melanoma cells. DR probe supports cell imaging and can be applied to mouse melanoma models to achieve melanoma diagnosis with higher accuracy and lower false-positive rates. DR probe is applicable to relevant research on melanoma .
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-
- HY-D1400
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Fluorescent Dye
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Others
|
|
HBTP-H2S (chloride) is a NIR fluorescent probe for in situ bioimaging of endogenous H2S in rice roots under Al 3+ and flooding stresses.
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-
- HY-163618
-
|
|
Fluorescent Dye
Monoamine Oxidase
|
Cancer
|
|
DHMQ is a NIR fluorescent probe that binds to the propylamino group of monoamine oxidase A (MAO-A). DHMQ tracks MAO-A activity in real-time by using fluorescence imaging on mice and cells .
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-
- HY-D1903
-
|
|
Fluorescent Dye
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Others
|
|
Fura Red AM is a fluorescent probe that can be used to visualize Ca 2+ distribution in the cytoplasm of undifferentiated cells. Fura Red AM operates at an excitation wavelength of 488 nm .
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-
- HY-161502
-
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|
Fluorescent Dye
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Others
|
|
DHX-SP is a fluorescent probe, which visualizes superoxide anion (O2 ·–) and peroxynitrite (ONOO –) during ferroptosis of PC12 cells and in the Parkinson’s disease model .
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-
- HY-D3194
-
|
|
Fluorescent Dye
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Others
|
|
CDy14 is a fluorescent probe targeting the extracellular polysaccharide Psl. CDy14 enables the detection of biofilms. CDy14 can be used for research on chronic bacterial infections .
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-
- HY-175074
-
|
|
Fluorescent Dye
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Others
|
|
C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium is a fluorescently labeled GM1 ganglioside probe. C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium can be used as a probe in biological experiments .
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-
- HY-141667
-
|
7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole
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Fluorescent Dye
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Others
|
|
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule .
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-
- HY-108715A
-
|
|
Fluorescent Dye
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Neurological Disease
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|
RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
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-
- HY-130785
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Fluorescent Dye
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Others
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|
LysoFP-NH2 is a lysosomal-targeted fluorescent probe with amino acid functionalized derivatives. LysoFP-NH2 can be used to detect lysosomal NO levels in living cells .
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-
- HY-P5287
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
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-
- HY-D3306
-
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|
Fluorescent Dye
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Others
|
|
Tubulin-RedTracker is a paclitaxel-derived fluorescent microtubule-binding probe. Tubulin-RedTracker induces F-actin cytoskeleton defects at relatively high concentrations. (Ex/Em = 652/669) .
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-
- HY-N16325
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Fluorescent Dye
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Others
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|
Golgi-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Golgi-Laurdanmimics the structure NBD C6 Ceramide that can be used for the study of the Golgi apparatus .
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-
- HY-DY1020
-
|
|
Fluorescent Dye
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Others
|
Rhod-2 (solution) is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
Solvent and concentration: DMSO: 1 mM
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-
- HY-DY1075
-
|
|
G-quadruplex
|
Neurological Disease
|
N-Methylmesoporphyrin IX (NMM) (solution) , a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
Solvent and concentration: DMSO: 2 mM
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-
- HY-W800694
-
|
|
Fluorescent Dye
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Others
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|
BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
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-
- HY-D1422
-
|
BDNCA-346
|
Fluorescent Dye
|
Others
|
|
ER Tracker Yellow is an endoplasmic reticulum-targeted temperature-visible fluorescent probe. ER Tracker Yellow has high temperature sensitivity (3.9%/°C) and is not affected by pH and Ca 2+ interference. ER Tracker Yellow can be used for real-time monitoring of local temperature changes in the ER area. ER Tracker Yellow maintains its function in fixed cells. ER Tracker Yellow is suitable for various cell lines and primary cells, such as HeLa cells, MEF cells, and other cells .
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-
- HY-168757
-
|
|
PSMA
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Cancer
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|
PSMA precursor-1 is a precursor in the synthesis of prostate-specific membrane antigen (PSMA) ligands and fluorescent probes that have been used in the detection of PSMA in LNCaP and PC3 cells .
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-
- HY-P5287A
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
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-
- HY-Y1309S
-
|
Furro ER-d8; NSC 9586-d8; Nako TRB-d8
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Endogenous Metabolite
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Others
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|
1-Naphthol-d8 is the deuterium labeled 1-Naphthol . 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe .
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-
- HY-W441021
-
|
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Liposome
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Others
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|
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
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-
- HY-D3377
-
|
LysoRhoNox
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Fluorescent Dye
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Others
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|
HMRhoNox-M (LysoRhoNox) is a selective fluorescent probe for labile Fe 2+ with an orange fluorescence, and its excitation/emission wavelength is λₑₓ/λₑₘ = 555/575 nm. HMRhoNox-M undergoes N-oxide deoxygenation mediated by Fe 2+, converting from a non-fluorescent spirocyclic closed form to a fluorescent quinone open form. HMRhoNox-M is used to detect labile Fe 2+ in living cells .
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-
- HY-125372
-
|
ABAO
|
Biochemical Assay Reagents
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Others
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|
2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
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-
- HY-Y1309R
-
|
Furro ER (Standard); NSC 9586 (Standard); Nako TRB (Standard)
|
Reference Standards
Endogenous Metabolite
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Others
|
|
1-Naphthol (Standard) is the analytical standard of 1-Naphthol. This product is intended for research and analytical applications. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.
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-
- HY-D0039
-
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Fluorescent Dye
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Others
|
|
3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM .
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-
- HY-W007465
-
-
- HY-123696
-
|
|
Fluorescent Dye
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Others
|
|
CDy9 is a highly selective fluorescent probe. CDy9 can be used to detect mouse embryonic stem cells. ( λ exc. / λ em.：563 nm/578 nm) .
|
-
- HY-D1583
-
|
DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate
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Fluorescent Dye
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Others
|
|
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
|
-
- HY-145746
-
|
|
Fluorescent Dye
PD-1/PD-L1
|
Inflammation/Immunology
Cancer
|
|
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
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-
- HY-128536
-
|
|
Fluorescent Dye
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Others
|
|
KMG-104AM is a Mg 2+ fluorescent probe. KMG-104AM is a membrane-permeable ester-modified derivative of KMG-104, which serves as a reporter and imaging agent. KMG-104AM can track the increase in intracellular free magnesium ion concentration induced by mitochondrial uncoupling. KMG-104AM enables visualization of the three-dimensional distribution of intracellular magnesium ion concentration. KMG-104AM is applicable to research related to the functions of intracellular magnesium ions .
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-
- HY-149203
-
|
|
Fluorescent Dye
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Others
|
|
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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-
- HY-120993
-
|
1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium
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Fluorescent Dye
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Others
|
|
1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .
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-
- HY-D2729
-
|
|
Fluorescent Dye
|
Infection
|
|
Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent probe that specifically labels Mycobacterium tuberculosis (Mtb). Cy3-NO2-tre generated fluorescence after activation by a specific nitroreductase, Rv3368c, which is conserved in the Mycobacteriaceae. Cy3-NO2-tre effectively imaged mycobacteria within infected host cells, tracked the infection process, and visualized Mycobacterium smegmatis being endocytosed by macrophages (Ex/Em= 540-550/575-625 nm) .
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-
- HY-119323
-
|
|
Fluorescent Dye
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Others
|
|
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
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-
- HY-DY1014
-
|
|
Fluorescent Dye
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Others
|
ATP-Red 1 (solution) is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).
Solvent and concentration: DMSO: 1 mM
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-
- HY-155524
-
|
|
Apoptosis
|
Cancer
|
|
Anticancer agent 134 (compound 6a) is a environment-sensitive fluorescent probe and an apoptosis inducer, making a distinction between the tumor and normal tissues. Anticancer agent 134 localizes to the nuclear bodies in tumor slices .
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-
- HY-N16309
-
|
|
Fluorescent Dye
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Others
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
- HY-D2948
-
|
|
Fluorescent Dye
|
Others
|
|
SNAP-430 is a (diethylamino) coumarin-labeled SNAP tag fluorescent probe. SNAP-430 can be used for making SNAP-tag fusion proteins inside living cells, on cell surfaces, or in vitro.
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-
- HY-176513
-
|
|
Fluorescent Dye
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Others
|
|
Cy-OH-LP is a turn-on fluorescent and photoacoustic probe that can detect lipid-associated hydroxyl radicals. Cy-OH-LP can be oxidized to Cy7 in the presence of hydroxyl radicals, which displays weak fluorescent and photoacoustic signals in water-soluble environments and strong fluorescent and photoacoustic signals in lipid-rich environments due to its lipid solubility. Cy-OH-LP can be used for in vivo photoacoustic imaging of hydroxyl radicals .
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-
- HY-D2346
-
|
|
Fluorescent Dye
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Others
|
|
HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
|
-
- HY-138241
-
|
|
Fluorescent Dye
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Others
|
|
PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance at 591 nm. PBD-BODIPY has been used to measure the activity of radical-trapping antioxidants in cell-free assays. It has also been used as a fluorescent probe for the detection of epoxidation activity.
|
-
- HY-DY1091
-
|
Fluorexon (solution)
|
Fluorescent Dye
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Others
|
Calcein (solution) (Fluorexon (solution)) is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
Solvent and concentration: DMSO: 2 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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-
- HY-15534
-
|
CBIC2
|
Fluorescent Dye
|
Others
|
|
JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
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-
- HY-120421
-
|
|
Sigma Receptor
|
Cancer
|
|
SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research .
|
-
- HY-D3314
-
|
NBD-SAG
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Fluorescent Dye
DGK
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Others
|
|
1-NBD-Stearoyl-2-arachidonoyl-sn-glycerol (NBD-SAG) is a fluorescently labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol (HY-131897). 1-NBD-Stearoyl-2-arachidonoyl-sn-glycerol acts as a fluorescent probe for the measurement of DGKε enzymatic activity .
|
-
- HY-D2443
-
|
|
Fluorescent Dye
|
Cancer
|
|
AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
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-
- HY-D2997
-
|
|
Fluorescent Dye
|
Cancer
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1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H2S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H2S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H2S activation .
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- HY-79602
-
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Biochemical Assay Reagents
Drug Derivative
Drug Intermediate
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Others
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p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .
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- HY-P4703
-
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Oxytocin Receptor
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Others
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Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro. Hydrin 1′ targets oxytocin receptor and derives a fluorescent probe of the oxytocin receptor .
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- HY-164055
-
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Fluorescent Dye
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Cancer
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|
HL1 is a Schiff base ligand. HL1 exhibits chelation-enhanced fluorescence effect when forming complexes and can be used as a fluorescent probe for metal ions. HL1 can be used for the research of cancer .
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- HY-P5367
-
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PMDM6-F
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Fluorescent Dye
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Others
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5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)
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- HY-DY1068
-
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Fluorescent Dye
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Others
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Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
Solvent and concentration: DMSO: 10 mM
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- HY-D3253
-
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Fluorescent Dye
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Others
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IR 650 azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 azide is a terminal azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 633nm, Em = 647nm)
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- HY-D2965
-
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SPG1
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Fluorescent Dye
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Others
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SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
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- HY-P991650
-
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PSMA
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Cancer
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MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
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- HY-115640
-
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TrxR
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Others
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TRFS-green is a highly selective off−on fluorescent probe for imaging selenoprotein thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. After it is activated by TrxR, the maximum absorbance shifts to around 440 nm .
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- HY-D3265
-
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Fluorescent Dye
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Others
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IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm
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- HY-150352
-
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Biochemical Assay Reagents
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Others
|
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Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
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- HY-176958
-
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FAP
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Others
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OncoFAP-EN-DOTAGA is a FAP (fibroblast activation protein) targeting conjugate compound. OncoFAP-EN-DOTAGA can chelate radioactive isotopes (such as ) Ga-68 or fluorescent agent and can be used as a probe with targeting binding functions .
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- HY-W356116
-
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Nbd-ceramide
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Fluorescent Dye
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Others
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C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .
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- HY-D2985
-
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Mitochondrial Metabolism
Fluorescent Dye
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Others
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MI-BP-CC is a mitochondrial-targeting near-infrared fluorescent probe. MI-BP-CC can specifically localize in the mitochondria of living cells. MI-BP-CC visualizes viscosity with an emission wavelength of 722 nm for detecting mitochondrial viscosity .
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- HY-D2094
-
|
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Fluorescent Dye
|
Inflammation/Immunology
Cancer
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PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
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- HY-D2952
-
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Fluorescent Dye
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Others
|
|
BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca 2+ concentration and serves as a highly sensitive Ca 2+ fluorescent indicator .
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- HY-D3221
-
|
|
Fluorescent Dye
Monoamine Oxidase
Amyloid-β
|
Neurological Disease
|
|
MAO Probe 1 is a reactive two-photon fluorescent probe capable of crossing the blood-brain barrier, which is used to detect the activity of monoamine oxidases (MAO-A/MAO-B), with Km values of 70 μM (MAO-A) and 75 μM (MAO-B), respectively. IBC 2 (benzo[g]imino-coumarin 2), the enzymatic product of MAO Probe 1, can further specifically bind to and image Aβ plaques, enabling in vivo two-photon co-monitoring of MAO activity and Aβ plaques. MAO Probe 1 can be used in Alzheimer's disease research (IBC 2: Ex/Em = 850 nm/570-620 nm) .
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- HY-125623
-
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Fluorescent Dye
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Others
|
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MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].
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- HY-152231
-
|
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Fluorescent Dye
Ligands for E3 Ligase
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Others
|
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BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm) .
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- HY-W008048S
-
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Isotope-Labeled Compounds
Nucleoside Antimetabolite/Analog
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Others
|
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2',3'-O-Isopropylideneadenosine- 13C5 is the 13C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
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- HY-D0717
-
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Diaminofluorescein-FM diacetate
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Fluorescent Dye
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Cancer
|
|
DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
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-
- HY-D2975
-
|
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Fluorescent Dye
|
Cardiovascular Disease
|
|
TTVP is a high-performance, blood activated AIE near-infrared fluorescent probe. TTVP can display hemorrhagic areas in the mouse brain with ultra sensitivity and high contrast specificity. TTVP provides a visual assessment tool for the study of hemorrhagic conditions .
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-
- HY-118581
-
|
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Topoisomerase
|
Cancer
|
|
Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage . Coralyne chloride can be used for preparing?coralyne derivatives?as DNA binding fluorescent probes .
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- HY-D3233
-
|
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Fluorescent Dye
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Others
|
|
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
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- HY-B1422
-
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Aminacrine
|
Bacterial
HIV
|
Infection
|
|
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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-
- HY-D3311
-
|
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Fluorescent Dye
|
Cancer
|
|
M1219 is a GSH/ATP dual near-infrared activated fluorescent probe that enables independent real-time monitoring of dynamic changes in intracellular GSH and ATP without spectral crosstalk (GSH: Ex=640 nm, Em=740~800 nm; ATP: Ex=594 nm/610 nm, Em=650~700 nm). M1219 not only visualizes the metabolic regulatory mechanism of TNBC under single/dual-target inhibition of SLC7A11/GLUT1 and accurately evaluates its in vivo efficacy, but also achieves precise localization of the TNBC tumor invasion boundary. M1219 can be used for the research of triple-negative breast cancer .
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-
- HY-D0150
-
|
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Fluorescent Dye
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Others
|
|
Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
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-
- HY-DY1073
-
|
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Fluorescent Dye
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Others
|
MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state) , and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction) .
Solvent and concentration: DMSO: 2 mM
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- HY-150352C
-
|
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Biochemical Assay Reagents
|
Others
|
|
Dextran-COOH (MW 100 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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-
- HY-D3254
-
|
|
Fluorescent Dye
|
Others
|
|
IR 650 picolyl azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 picolyl azide is a terminal picolyl azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 650nm, Em = 670nm)
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-
- HY-W278706
-
|
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Fluorescent Dye
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Others
|
|
N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds .
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![N-[4-(2-Benzimidazolyl)phenyl]maleimide](//file.medchemexpress.com/product_pic/hy-w278706.gif)
- HY-150352D
-
|
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Biochemical Assay Reagents
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Others
|
|
Dextran-COOH (MW 250 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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-
- HY-150352A
-
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Biochemical Assay Reagents
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Others
|
|
Dextran-COOH (MW 10 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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-
- HY-171417
-
|
|
CD38
|
Cancer
|
|
6-Alkyne-F-araNAD is an irreversible inhibitor of CD38. 6-Alkyne-F-araNAD helps other fluorescent probes (such as SR101−F-araNMN) to more clearly observe the localization of intracellular CD38 .
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-
- HY-172508
-
|
|
Fluorescent Dye
Phosphoramidites
|
Others
|
|
Perylene dU phosphoramidite is a bright and extremely photostable fluorescent polycyclic aromatic hydrocarbon (PAH) label with a quantum yield approaching quantitative. Due to the low lifetime of fluorescence, this probe does not form excimers.With this phosphoramidite, perylene can be introduced into DNA by automated oligonucleotide synthesis.
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-
- HY-150352E
-
|
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Biochemical Assay Reagents
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Others
|
|
Dextran-COOH (MW 500 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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-
- HY-D2976
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
|
|
CN-N2 is a visible light fluorescent probe. CN-N2 has high selectivity, rapid penetration, good biocompatibility, and imaging effects. CN-N2 is suitable for intraoperative rapid imaging of atherosclerotic plaque .
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-
- HY-150352B
-
|
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Biochemical Assay Reagents
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Others
|
|
Dextran-COOH (MW 70 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
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-
- HY-124197S
-
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Isotope-Labeled Compounds
Fluorescent Dye
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Others
|
|
Coumarin hydrazine-d7 is the deuterium labeled Coumarin hydrazine (HY-124197). Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
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-
- HY-151109
-
|
|
Fluorescent Dye
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Others
|
|
IR-990 is an activatable NIR-II fluorescent probe with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H2O2 in vivo. IR-990 is a powerful diagnosis of agent-induced liver injury (DILI) .
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-
- HY-169838
-
|
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Biochemical Assay Reagents
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Others
|
|
WYneC can specifically bind to sulfinylated proteins in living cells and then react with fluorescent probes containing azide groups for detection. In the field of redox biology, WYneC can also be used to determine the occupancy of S-sulfinylation sites or as a carrier to deliver substances to mitochondria .
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-
- HY-D2991
-
|
|
Bacterial
Fluorescent Dye
|
Infection
|
|
CDG-DNB3 is a selective fluorescent probe for Mycobacterium tuberculosis. CDG-DNB3 provides rapid and specific labeling of live Mycobacterium tuberculosis. CDG-DNB3 can image Bacillus Calmette-Guérin phagocytosis in real time .
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-
- HY-D3241
-
|
|
Fluorescent Dye
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Others
|
|
CD649.2 is a red-emitting copper-targeted acylimidazole-reactive Fluorescent probe and a highly specific Cu 2+ detection reagent. CD649.2 enables visualization of labile Cu 2+ pools and their dynamic changes in living cells .
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-
- HY-D3263
-
|
|
Fluorescent Dye
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Others
|
|
IR 650 NHS ester is a far-red-fluorescent probe with NHS ester. NHS ester is the most popular amine-reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. (Ex=651nm, Em=668 nm)
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-
- HY-131045
-
|
HCC-Amino-D-alanine hydrochloride
|
Bacterial
|
Infection
|
|
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
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-
- HY-D3198
-
|
|
Fluorescent Dye
Endogenous Metabolite
|
Cancer
|
|
NIR-fluorescent ceramide is a neutral near-infrared (NIF) fluorescent probe (λem=650 nm) based on the C-bridged nitrobenzoxadiazole SCOTfluor core, which enables visualization of lipid metabolic processes such as sphingolipid trafficking. The emission signal of NIR-fluorescent ceramide increases significantly in liposomal environments. NIR-fluorescent ceramide acts as an intracellular trafficking tracer, localizing to regions surrounding the endoplasmic reticulum and Golgi apparatus within a short period, and then translocating to recycling lysosomes over a longer period, thus enabling real-time visualization of sphingolipid trafficking and biological lipid functions in living cells. NIR-fluorescent ceramide also generates metabolic uptake profiles and provides multiple metabolic readouts in human cancer cell lines .
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-
- HY-114354
-
|
BOD FL alkyne
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .
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-
- HY-D1991
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 647 is a carborhodamine fluorophore and imaging tracer with photostable properties. ATTO 647 serves as a fluorescent probe to investigate cell membrane structure and diffusion characteristics. When conjugated with wheat germ agglutinin, ATTO 647 specifically binds to N-acetyl-β-D-glucosamine and sialic acid residues on membrane glycoproteins, enabling single-molecule tracing of glycoprotein diffusion. ATTO 647 exhibits highly stable fluorescence properties with significantly reduced blinking in mounting media such as ROXS (AA/MV) and ROXS (TX/TQ), whereas its brightness properties vary in Ibidi-MM and Vectashield. ATTO 647 can also be used to label histone H2B-GFP in fixed cells for confocal microscopy photobleaching experiments .
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- HY-N16300
-
|
|
Fluorescent Dye
|
Others
|
|
Mito-laurdan bromide, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Mito-laurdan bromide contains a cationic triphenylphosphonium moiety, which accumulates at the inner mitochondrial membrane due to its negative membrane potential, connected via a 3 carbon linker .
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-
- HY-178588
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
Fluorescein-12-dUTP is a fluorescent labeling and detection reagent that can be used for nucleic acid synthesis. Fluorescein-12-dUTP can be used to synthesize labeled DNA probes for in situ hybridization, microarray or western blot analysis .
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-
- HY-D3214
-
|
|
Fluorescent Dye
|
Others
|
|
NIR-Cu (Ⅱ) is a near-infrared fluorescent Cu 2+ probe. NIR-Cu (Ⅱ) enables fluorescence imaging of Cu 2+ in living mice. NIR-Cu (Ⅱ) reduces self-absorption and exhibits minimal photobleaching, thus supporting in vivo imaging applications .
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-
- HY-D2990
-
|
|
Fluorescent Dye
|
Others
|
|
KSA01 is a two-dimensional fluorescent probe. KSA01 can detect SA-β-gal activity and sense lysosomal pH. KSA01 can accurately distinguish cellular aging from other pathological states with high expression of β-gal .
|
-
- HY-D2946
-
|
BC-TMR
|
Fluorescent Dye
|
Infection
|
CLIP-TMR (BC-TMR) is a TMR-labeled CLIP tag fluorescent probe. CLIP-TMR combines the high specificity recognition ability of the CLIP-tag and the excellent optical performance of the TMR fluorophore, and can be used for the specific labeling and visualization of the HCV NS5A protein .
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-
- HY-D2939
-
|
|
Fluorescent Dye
|
Others
|
BGSBD is a SNAP-tag-based fluorescent probe (Ex/Em: 435 nm/516 nm) based on the environmentally sensitive fluorescent group SBD, specifically designed for protein labeling of live cells without washing. BGSBD achieves a 280-fold fluorescence enhancement after labeling by ingeniously utilizing the hydrophobic binding pocket of the SNAP-tag protein, providing an ideal tool for real-time monitoring of protein dynamics within cells .
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-
- HY-D3346
-
|
|
Fluorescent Dye
|
Others
|
|
Dusquench1 NHS ester is an amino-reactive fluorescent quencher (it does not emit light and has no emission wavelength, Ex = 480-580 nM), specially designed for labeling proteins, oligonucleotides and other biopolymers containing primary amines. It is a core reagent in the fields of qPCR probes, FRET detection and molecular beacons.
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-
- HY-149170
-
|
|
5-HT Receptor
Monoamine Transporter
|
Neurological Disease
|
|
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation .
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-
- HY-D1341
-
|
|
Fluorescent Dye
|
Cancer
|
|
Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C .
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-
- HY-N16306
-
|
|
Fluorescent Dye
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Others
|
|
Lyso-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Lyso-Laurdan accumulates in the lysosome via a morpholine group that is entrapped in lysosome via protonation to its cationic form in the acidic compartment. Lyso-laurdan is localized to lysosomes, allowing for the study of lysosomal membranes .
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-
- HY-130783
-
|
|
Fluorescent Dye
|
Others
|
|
LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.
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-
- HY-W116606
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification .
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-
- HY-155486
-
|
|
Fluorescent Dye
|
Cancer
|
|
HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .
|
-
- HY-160059
-
|
|
Fluorescent Dye
|
Cancer
|
|
JHIT2e aptamer sodium is a molecular probe based on the aptamer JHIT2 of human liver cancer cell line HepG2 cells. JHIT2e aptamer sodiu retains the ability to specifically bind HepG2 and can deliver fluorescent materials or radionuclides to tumors .
|
-
- HY-D1723
-
|
|
DNA Stain
|
Others
|
|
EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) .
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-
- HY-D3354
-
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Fluorescent Dye
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Others
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|
BP Fluor 350 alkyne is a blue fluorescent dye probe (Ex/Em = 346 nm/455 nm) that contains a terminal acetylene group (-C≡CH). BP Fluor 350 is specifically used for copper-catalyzed azide-alkyne cycloaddition and is employed to label azide groups in biological samples.
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-
- HY-DY1097
-
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Fluorescent Dye
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Others
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Thiazole Orange (solution) is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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-
- HY-D3391
-
|
|
Bacterial
|
Infection
|
|
RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .
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-
- HY-B1422R
-
|
Aminacrine (Standard)
|
Reference Standards
Bacterial
HIV
|
Infection
|
|
9-Aminoacridine (Standard) is the analytical standard of 9-Aminoacridine. This product is intended for research and analytical applications. 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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-
- HY-W140535
-
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Fluorescent Dye
MOFs
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Others
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|
Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent ruthenium complex. Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is used in biological and chemical fields as a fluorescent indicator dye and an electrochemiluminescent probe .
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-
- HY-D2988
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
BIN-3 is a novel near-infrared fluorescent probe. BIN-3 has excellent biocompatibility, no cytotoxicity, and no hemolysis. BIN-3 can be used for highly sensitive and selective imaging of drug-resistant bacterial infections expressing β-lactam enzymes in live mice .
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-
- HY-D1300
-
|
LysoTracker Red DND-99
|
Biochemical Assay Reagents
Fluorescent Dye
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Others
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|
LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
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-
- HY-147738
-
|
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Fluorescent Dye
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Others
|
|
SQM-NBD is a potent and selectiveAIE fluorescent probe. SQM-NBD exhibits excellent sensitivity to Cys and Hcy with the LOD of 54 nM and 72 nM, respectively.SQM-NBD has good cell permeability and low cytotoxicity. SQM-NBD has the potential for Cys/Hcy identification under physiological and pathological conditions .
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-
- HY-175127
-
|
|
Fluorescent Dye
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Others
|
|
N-Dodecanoyl-L-homoserine lactone-3-hydrazone-fluorescein is a fluorescently-tagged probe. N-Dodecanoyl-L-homoserine lactone-3-hydrazone-fluorescein can be used in the research of O-DDHSL and 3O-C12-HSL detection .
|
-
- HY-149596
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
PTZ-LD is a phenothiazine (HY-Y0055)-based fluorescent probe for lipid droplets (LDs) detection. PTZ-LD is apparently emissive in LDs with high specificity. (Ex/Em=488/570-620 nm). PTZ-LD can be used for diabetic cataract (DC) research .
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-
- HY-D3416
-
|
TAMRA-2,4-dinitroaniline
|
Fluorescent Dye
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Others
|
|
TMR-DN (TAMRA-2,4-dinitroaniline) is a bright orange fluorescent probe that binds to the SRB-2 aptamer, with a Kd value of 35 nM for the SRB-2 aptamer. TMR-DN exhibits low background fluorescence, enabling wash-free live-cell RNA imaging .
|
-
- HY-D0988
-
|
R-PE
|
Fluorescent Dye
Apoptosis
|
Cancer
|
|
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
|
-
- HY-W800691
-
|
|
Fluorescent Dye
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Others
|
|
BP Fluor 350 Picolyl Azide is a blue-fluorescent azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
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-
- HY-D2958
-
|
|
Fluorescent Dye
|
Others
|
|
ZP1BG is a SNAP tag fluorescent probe for detecting Zn 2+, which is formed by the covalent connection of the zinc sensor ZP1 from the Zinpyr family with the benzyl guanine group. ZP1BG can be used to detect the concentration of Zn 2+ in neuronal organelles such as the Golgi apparatus and mitochondria .
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-
- HY-18909
-
|
|
Src
Bcr-Abl
Pyk2
p38 MAPK
c-Kit
|
Others
|
|
Multi-kinase-IN-11 (Compound 1a) is a DFG-out conformation-targeted multi-kinase inhibitor, including SRC, LCK, ABL, PYK2, CSK, HCK, P38 and C-KIT. Multi-kinase-IN-11 serves as a scaffold for the preparation of fluorescently labeled binding probes and affinity matrices .
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-
- HY-165426
-
|
|
Fluorescent Dye
Glutaminase
|
|
|
HB-230 is a red fluorescent transglutaminase 2 (TG2) probe. HB-230 complexes with TG2 and α2-macroglobulin via the LRP1 pathway for efficient endocytosis. The excitation and emission wavelengths of HB-230 are 649 and 665 nm, respectively .
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-
- HY-D3165
-
|
|
Fluorescent Dye
|
Cancer
|
|
DCM-gal-CF is a fluorescent probe containing a DCM fluorophore scaffold and a D-galactose recognition moiety. DCM-gal-CF itself shows weak fluorescence, and its fluorescence is enhanced after cleavage by β-galactosidase. DCM-gal-CF can be used to detect β-galactosidase activity .
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-
- HY-D1021
-
|
Aminoallyl-dUTP sodium salt
|
DNA/RNA Synthesis
|
Others
|
|
AA-dUTP (Aminoallyl-dUTP) sodium salt is a reverse transcriptase and DNA polymerase I substrate with probe precursor activity. AA-dUTP sodium salt undergoes enzymatic incorporation into DNA during cDNA synthesis and nick translation. AA-dUTP sodium salt generates amine-modified DNA, which can be used for labeling with amine-reactive fluorescent dyes .
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-
- HY-118667
-
|
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Liposome
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Others
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|
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
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-
- HY-79602S1
-
-
- HY-D3173
-
|
TPG-456
|
Fluorescent Dye
GCGR
|
Metabolic Disease
|
|
TP-α is a glucagon-selective two-photon fluorescent probe with a Kd of 65 μM. TP-α directly interacts with glucagon to produce significant fluorescence enhancement. TP-α selectively stains viable glucagon-secreting α cells in pancreatic islets, enabling visualization of their localization, distribution and availability. TP-α is applicable to diabetes research .
|
-
- HY-D2987
-
|
|
Fluorescent Dye
Bacterial
|
Others
|
|
BacGO is a highly selective, wash free fluorescent probe for Gram positive bacteria. BacGO binds to the carbohydrate structure in peptidoglycan through boric acid and exhibits depolymerization induced luminescence (DIE) properties. BacGO can be used for imaging complex environmental samples (such as activated sludge) and flat plate bacteria without affecting bacterial activity .
|
-
- HY-P10772
-
|
|
Peptide-Drug Conjugates (PDCs)
EBV
|
Cancer
|
|
L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM .
|
-
- HY-D2971
-
|
|
Fluorescent Dye
Autophagy
|
Neurological Disease
|
|
NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells .
|
-
- HY-D2983
-
|
|
Fluorescent Dye
Histone Acetyltransferase
|
Infection
|
|
ARHB is a highly selective and sensitive NAT2 fluorescent probe suitable for real-time detection of NAT2 activity in various bacteria. ARHB can successfully penetrate the bacterial cells, and the fluorescence intensity is positively correlated with the expression level of NAT2. ARHB is used for high-throughput screening of natural inhibitors for tuberculosis .
|
-
- HY-W250727
-
|
6-(p-Tolylamino)naphthalene-2-sulfonate sodium
|
Fluorescent Dye
|
Others
|
|
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
|
-
- HY-175086
-
|
DOPI-3,4,5-P3-fluorescein triethylammonium; PI(3,4,5)P3-fluorescein triethylammonium; PIP3[3',4',5']-fluorescein triethylammonium
|
Fluorescent Dye
|
Others
|
|
PtdIns-(3,4,5)-P3 is a second messenger. PtdIns-(3,4,5)-P3-fluorescein triethylammonium is a fluorescent probe that can detect any protein that has a high-affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids .
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-
- HY-79602R
-
|
|
Biochemical Assay Reagents
Reference Standards
Drug Derivative
Drug Intermediate
|
Others
|
|
p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .
|
-
- HY-P10772A
-
|
|
Peptide-Drug Conjugates (PDCs)
EBV
|
Cancer
|
|
L2P4 TFA is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 TFA exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM .
|
-
- HY-175123
-
|
|
Fluorescent Dye
|
Others
|
|
3'-O-(5-Chloroanthraniloyl)-2'-deoxyadenosine-5'-O-triphosphate (sodium) is a fluorescently labeled derivative of 2'-deoxyadenosine triphosphate (dATP). 3'-O-(5-Chloroanthraniloyl)-2'-deoxyadenosine-5'-O-triphosphate (sodium) can be used as a probe.
|
-
- HY-114541
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin-7-pinacolboronate is a fluorescent probe. Taking hydrogen peroxide for instance, Coumarin-7-pinacolboronate and HOO- undergo a nucleophilic reaction to produce INT1. The chemical reaction mechanisms are nearly identical for the reactions of Coumarin-7-pinacolboronate with hydrogen peroxide, hypochlorous acid, peroxynitrite, and tyrosine hydroperoxide, respectively .
|
-
- HY-D2938
-
|
|
Fluorescent Dye
|
Others
|
|
BG-PEG11-Cya-NR is a high-performance, non washable, fluorescent opening probe. BG-PEG11-Cya-NR has very weak fluorescence in polar environments (such as aqueous solutions), while its fluorescence is significantly enhanced in non-polar environments (such as the lipid bilayer of cell membranes) .
|
-
- HY-175163
-
|
|
Photosensitizer
|
Cancer
|
|
TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer .
|
-
- HY-D1063
-
|
|
Fluorescent Dye
Apoptosis
Reactive Oxygen Species (ROS)
|
Cancer
|
|
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
|
-
- HY-D2994
-
|
SNAP-MaP555
|
Fluorescent Dye
|
Others
|
|
SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
|
-
- HY-D1509
-
|
|
Fluorescent Dye
|
Others
|
|
Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
|
-
- HY-D0157
-
|
|
Biochemical Assay Reagents
|
Others
|
|
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .
|
-
- HY-D3234
-
|
|
Fluorescent Dye
|
Others
|
|
Cy-AP is a hypoxia-sensitive near-infrared Fluorescent probe (emission wavelength: 725 nm). Cy-AP exhibits no fluorescence under normoxic microenvironments, while under hypoxic microenvironments, its azo group is reduced, releasing strong near-infrared fluorescence with an emission at 725 nm. Cy-AP enables visualization of intracellular hypoxic status through multiple imaging modalities .
|
-
- HY-D3230
-
|
|
Fluorescent Dye
|
Others
|
|
FLCS1 is a BODIPY-based Fluorescent probe and selective copper (I) ion binder (λex = 630 nm, λemis = 660 nm). Binding of FLCS1 to copper (I) ions induces fluorescence turn-on. Addition of copper (I) to a methanolic solution of FLCS1 causes a slight red shift (4 nm) in the maximum absorption wavelength (λmax) in the UV-Vis spectrum .
|
-
- HY-149028
-
|
|
Fluorescent Dye
|
Others
|
|
Mem-C1C18 is a polarity-sensitive fluorescent probe with excellent plasma membrane anchoring, high brightness and a sensitive response to environmental polarity by altering the fluorescence lifetime. Mem-C1C18 can be used to quantify changes in the polarity of the plasma membrane during iron death .
|
-
- HY-D2940
-
|
SiR650-BG
|
Fluorescent Dye
|
Others
|
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
|
-
- HY-163324A
-
|
|
Cytochrome P450
|
Others
|
|
2-Me PeER is a rhodamine dye-based fluorescent probe that detects CYP3A4 activity. In fluorescence-activated cell sorting (FACS) based on CYP3A4 activity, homogeneous and functional human induced pluripotent stem cell (hiPSC)-derived hepatocytes and intestinal epithelial cells can be obtained with the aid of 2-Me PeER .
|
-
- HY-59303
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1H-Imidazole-5-carboxaldehyde can be used as a chemical reagent in organic synthesis reactions. 1H-Imidazole-5-carboxaldehyde can be used to prepare other imidazole compounds, such as imidazole pyrimidine and imidazolone. 1H-Imidazole-5-carboxaldehyde can also be used as biochemical dyes and fluorescent probes.
|
-
- HY-D0053
-
|
6-Carboxy-X-rhodamine
|
Fluorescent Dye
|
Others
|
|
6-ROX is a selective fluorescent probe and potential inhibitor of COX-2. 6-ROX binds to the active site of COX-2 and inhibits its conversion of arachidonic acid into prostaglandins. 6-ROX is often used in the field of optical imaging related to tumors and inflammation, and helps detect diseased tissues with high expression of COX-2 .
|
-
- HY-152103
-
|
|
Fluorescent Dye
|
Others
|
|
CB2-H is a dual-channel fluorescent probe for the simultaneous detection of HOCl and ONOO -. CB2-H enables the concurrent detection of HOCl and ONOO - at two independent channels without spectral cross-interference and can be applied for dual-channel fluorescence imaging of endogenously produced HOCl and ONOO - in living cells and zebrafish under different stimulants .
|
-
- HY-D3166
-
|
|
Fluorescent Dye
|
Others
|
|
CEMT is a carboxylesterase (CE) substrate and a ratiometric two-photon fluorescent reporter probe. CEMT can be hydrolyzed by CE to generate HMT, which is used for mitochondrial pH sensing. After activation by CE, CEMT exhibits ratiometric fluorescence changes in response to pH variations. CEMT targets and covalently binds to mitochondria, and can avoid leakage during acidification, thus enabling in situ imaging .
|
-
- HY-D2949
-
|
|
Fluorescent Dye
|
Others
|
|
SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
|
-
- HY-D3188
-
|
|
Fluorescent Dye
|
Cancer
|
|
gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase (GGT) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT, and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma .
|
-
- HY-181506
-
|
|
Fluorescent Dye
Molecular Glues
CaMK
c-Myc
Bcl-2 Family
Cadherin
|
Cancer
|
|
TYMJ-01 is a fluorescent probe and eEF2K degrader. TYMJ-01 induces dose-dependent and specific degradation of eEF2K via the ubiquitin-proteasome pathway, with a DC50 of 82 nM. TYMJ-01 inhibits the proliferation, migration and invasion of triple-negative breast cancer cells. TYMJ-01 enables dynamic fluorescent imaging of eEF2K degradation in triple-negative breast cancer cells; it enhances the anti-tumor activity of Paclitaxel (HY-B0015). TYMJ-01 can be used for the research of triple-negative breast cancer .
|
-
- HY-D1719A
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues .
|
-
- HY-W010042
-
|
L-(-)-Glucose
|
Fluorescent Dye
|
Metabolic Disease
Cancer
|
|
L-Glucose (L-(-)-Glucose) is a stereoisomer of D-Glucose (HY-B0389), which does not readily enter the brain. L-Glucose can promote food intake. L-glucose is combined with a fluorescence detector to produce a fluorescent probe that can be used to visualize and characterize cancer cells. L-Glucose also can be used in the research to enhance memory in mice .
|
-
- HY-172534
-
|
|
Fluorescent Dye
EGFR
TSPO
|
Cancer
|
|
BPN-01 is a fluorescent probe targeting translocator protein (TSPO) and human epidermal growth factor receptor 2 (HER2) with binding affinities of -10.7 kcal/mol for TSPO and -11.3 kcal/mol for HER2. BPN-01 is promising for research of solid tumor imaging during fluorescence image-guided surgery (FIGS) (Ex/Em = 475/510 nm) .
|
-
- HY-Y1309
-
|
Furro ER; NSC 9586; Nako TRB
|
Environmental Pollutants
Endogenous Metabolite
|
Others
|
|
1-naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media .
|
-
- HY-P11637
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Mitochondrial-targeted peptide BP19 is a fluorescent probe for the selective measurement of labile iron in the mitochondriairon. Mitochondrial-targeted peptide BP19 exhibits iron-selective sensing activity with mitochondrial accumulation, reduced fluorescence in iron-loaded cells, and fluorescence reinstatement upon iron chelation. Mitochondrial-targeted peptide BP19 evaluates mitochondrial labile iron levels in cultured fibroblasts with Friedreich's ataxia .
|
-
- HY-D3200
-
|
|
Fluorescent Dye
Cuproptosis
|
Others
|
|
Dns-LLC is a cell-permeable Cu +-selective fluorescent probe that forms a 1:1 complex with Cu +. The thiol group of Dns-LLC plays a key binding role, while the sulfonamide and amide groups jointly contribute to the stabilization of the complex. Upon binding to Cu + in aqueous buffer solutions, Dns-LLC generates a turn-on fluorescence response, which can be used for the detection of Cu + in the Golgi apparatus .
|
-
- HY-D2956
-
|
CLIP-GLA-NHS
|
Biochemical Assay Reagents
|
Others
|
|
BC-GLA-NHS (CLIP-GLA-NHS) is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .
|
-
- HY-34515
-
|
TMPhen; 3,4,7,8-Tetramethyl-1,10-phenanthroline
|
Biochemical Assay Reagents
|
Others
|
|
3,4,7,8-Tetramethyl-1,10-phenanthroline (TMPhen) is an organic molecule commonly used as a ligand or catalyst. It has a wide range of applications in different fields, such as organometallic chemical reactions, electrochemical detection, and organic optoelectronic devices. Due to its excellent performance in fluorescent probes, biosensors and photocatalytic reactions, it has been widely used in research in the fields of chemistry and life sciences.
|
-
- HY-W740363
-
|
5-AF hydrochloride
|
Fluorescent Dye
|
|
|
5-Aminofluorescein hydrochloride (5-AF hydrochloride) is a protein fluorescent labeling reagent with excellent fluorescence activity. It is widely used in cell imaging and molecular probes in biomedical research. 5-Aminofluorescein hydrochloride can be used to observe the location of proteins and their dynamic changes, providing in-depth biological understanding. 5-Aminofluorescein hydrochloride is also used to detect interactions between biomolecules and help analyze complex biological processes.
|
-
- HY-D2973
-
|
|
Fluorescent Dye
|
Others
|
|
YH-APN is a high-performance APN activated near-infrared fluorescent probe. YH-APN has high sensitivity, high selectivity, fast response, and can achieve extremely high tumor/normal tissue signal-to-noise ratio through in situ spraying. YH-APN can specifically distinguish cancer cells with high expression of APN from normal cells and monitor the migration of cancer cells .
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- HY-P11265
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GnRH Receptor
Fluorescent Dye
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Cancer
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YQGN-7 is a targeted fluorescent probe for the gonadotropin-releasing hormone receptor (RnRHR). YQGN-7 exhibits high selectivity and affinity for breast cancer cells (KD = 217.8 nM). YQGN-7 achieves precise visualization of the primary and metastatic lesions of breast cancer by targeting the highly expressed GnRHR in tumor cells. YQGN-7 can be used in the research of breast cancer breast-conserving surgery (BCS) .
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- HY-D1836
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VF 555 Tyramide
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Fluorescent Dye
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Others
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Vari Fluor 555 TSA (200x) , also know as VF 555 Tyramide. Vari Fluor 555 TSA (200x) is one of Vari Fluor TSA series fluorescent probes, which can be used for high-density in situ labeling assays. Vari Fluor TSA series target antigens via horseradish peroxidase (HRP), which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-203233
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Fluorescent Dye
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Others
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Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu 2+-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy .
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- HY-D3143
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Fluorescent Dye
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Cancer
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QM-B-CF is a sequential dual-lock chemiluminescent/fluorescent dual-mode probe designed for the specific detection of H2O2, and it can produce enhanced chemiluminescence upon photoirradiation. QM-B-CF generates chemiluminescent signals only under the conditions of H2O2 and light exposure in vitro, in cancer cells, and in tumor-bearing nude mice (Ex/Em = 514 nm/600 nm) .
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- HY-D3196
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Fluorescent Dye
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Cancer
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AG2 is a glucose uptake tracer and two-photon fluorescent probe. AG2 is taken up by cells via glucose-specific transport systems, rather than passive diffusion; it preferentially accumulates in cancer cells and colon cancer tissues compared with normal cells and tissues; it mainly localizes to mitochondria, with a small amount also distributed in the cytoplasm and cell membrane. AG2 can be used for colon cancer research .
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- HY-103242
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Amyloid-β
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Neurological Disease
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CRANAD-2 is a specific near-infrared (NIR) fluorescent probe for detecting Aβ plaques (unbound to Aβ: Ex=640 nm; Em=805 nm; after binding: Em=715 nm). CRANAD-2 penetrates the blood-brain barrier and has high affinity for Aβ aggregates, with a Kd value of 38 nM. CRANAD-2 is applicable to research related to Alzheimer's disease and neurodegenerative diseases .
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- HY-D3313
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15-Deoxy-Δ12,14-PGJ2-biotin
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Fluorescent Dye
Drug Derivative
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Others
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15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin-labled 15-Deoxy-Δ12,14-Prostaglandin J2 (HY-108568). 15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin can be used as a fluorescent probe.
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- HY-D0988A
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R-PE (concentrated solution)
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Fluorescent Dye
Apoptosis
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Others
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R-Phycoerythrin (R-PE) (concentrated solution) is found in Heterosiphonia japonica. R-Phycoerythrin (concentrated solution) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (concentrated solution) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .
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- HY-W090294
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Peri-dinaphthalene (purified by sublimation)
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Perylene, which is a polycyclic aromatic hydrocarbon composed of four linearly fused benzene rings, is commonly used as a pigment and dye in a variety of applications, including printing inks, plastics, and textiles. In addition, Perylene has potential uses in solar cells as photosensitizers and as fluorescent probes in biochemistry and materials science. Perylene's rigid planar structure endows it with unique electronic and optical properties, making it a versatile and important compound in many fields of chemistry and materials science.
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- HY-P992459
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ADC Antibody
Transmembrane Glycoprotein
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Cancer
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SGM-101 Antibody is a chimeric monoclonal antibody targeting carcinoembryonic antigen (CEA). SGM-101 Antibody can serve as a tumor-specific fluorescent imaging probe after being covalently conjugated with the near-infrared fluorescent dye BM104 . SGM-101 Antibody accumulates in CEA-positive tumor tissues via antigen-antibody specific binding, and emits near-infrared fluorescence to enable imaging of tumor lesions. SGM-101 Antibody can be used in research related to gastric cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer, breast cancer, peritoneal carcinomatosis, and liver metastases .
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- HY-D3187
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Fluorescent Dye
Glycosidase
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Infection
Cancer
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HMRef-αMan is a substrate-based green fluorescent probe (Ex/Em=465 nm/515 nm) targeting MAN2C1 (α-mannosidase). HMRef-αMan can be specifically cleaved by MAN2C1 to generate a highly fluorescent product, which thus gets activated to produce green fluorescence in malignant breast tissues, benign lesions and living cancer cells. The signal intensity of HMRef-αMan is directly correlated with MAN2C1 activity, and it can effectively detect tiny breast cancer lesions with a diameter of less than 1 mm. When used in combination with the red-emitting γ-glutamyl transpeptidase (GGT) probe gGlu-2OMe SiR600 (HY-D3188), HMRef-αMan enables precise optical differentiation of breast tissue types via a dual-color imaging strategy. HMRef-αMan has been widely used in the research of breast diseases such as breast cancer, fibroadenoma, phyllodes tumor and various types of papilloma .
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- HY-136675
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Fluorescent Dye
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Others
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ASMI is a ratiometric, two-photon excited fluorescent probe, composed of a highly two-photon active and biocompatible merocyanine fluorophore and an acrylate moiety as a thiol reactive site. ASMI is able to selectively detect and monitor mitochondrial Cys with rapid responsiveness, imaging living cells and intact tissues with high contrast and brightness at a depth of 150 μm. The two-photon action cross section (Φσmax) of ASMI is 65.2 GM, corresponding to an excitation wavelength (λex) of 740 nm.
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- HY-W419044A
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Fluorescent Dye
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Others
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Calcein calcium potassium is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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- HY-D0988B
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R-PE ammonium sulfate precipitate
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Fluorescent Dye
Apoptosis
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Others
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|
R-Phycoerythrin (R-PE) (ammonium sulfate precipitate) is found in Heterosiphonia japonica. R-Phycoerythrin (ammonium sulfate precipitate) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (ammonium sulfate precipitate) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .
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- HY-114346A
-
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Fluorescent Dye
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Others
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ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
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-
- HY-D3171
-
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Fluorescent Dye
Cholinesterase (ChE)
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Neurological Disease
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AD-BChE/HClO is a dual-target two-photon fluorescent probe. AD-BChE/HClO can release 4-methylumbelliferone via butyrylcholinesterase-mediated hydrolysis of the ester bond at position 7, as well as hypochlorous acid-mediated thiocarbonyl oxidation. AD-BChE/HClO enables two-photon imaging in nerve cells and mouse brain tissues via tail vein injection. AD-BChE/HClO can be used for the research of Alzheimer's disease .
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- HY-P10943
-
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Fluorescent Dye
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Inflammation/Immunology
Cancer
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APO-15 is a phosphatidylserine-binding fluorescent probe and apoptosis imaging reagent. APO-15 exhibits high chemical stability under proteolytic and oxidative conditions, enables quantification and imaging of drug-induced apoptosis in preclinical mouse models, and is applicable to fixed tissue samples and multiple in vivo administration routes (Ex = 488 nm; Em = 525 nm). APO-15 can be used in studies related to acute lung injury and breast cancer .
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- HY-W329161
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Fluorescent Dye
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Others
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Calcein sodium is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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- HY-W090065
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1-Pyrenemethylamine hydrochloride
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Biochemical Assay Reagents
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Others
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Pyren-1-ylmethanamine hydrochloride, Pyren-1-ylmethanamine hydrochloride is commonly used as a fluorescent probe in biochemistry and molecular biology to detect and study nucleic acids, proteins and other biomolecules, moreover, it has been used in analytical chemistry Among them, for the detection of heavy metals and other pollutants in environmental samples, the pyrene group in the molecule exhibits strong fluorescence properties, which makes it useful as a sensitive and selective detector in various applications.
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- HY-D3220
-
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Fluorescent Dye
Amyloid-β
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Neurological Disease
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|
PTO-41 is a blood-brain barrier-permeable near-infrared fluorescent probe that targets β-amyloid oligomers (Aβ Oligomers, AβOs) with a Kd of 349 nM. PTO-41 exhibits low cytotoxicity, high sensitivity to β-amyloid oligomers in in vitro phantom imaging, and can be rapidly cleared from the brain. PTO-41 is applicable to the research of Alzheimer's disease (Ex/Em = 538 nM/680 nM) .
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- HY-D3225
-
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Fluorescent Dye
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Neurological Disease
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|
MD-B is a •OH Fluorescent probe with blood-brain barrier permeability. MD-B undergoes single-electron oxidation by hydroxyl radicals (•OH), which triggers fluorescence enhancement and enables in-situ imaging of •OH. MD-B allows imaging analysis of hydroxyl radicals (•OH) in the mouse brain, revealing a positive correlation between elevated •OH levels and the severity of depressive phenotypes. MD-B can be used in depression-related research .
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- HY-149422
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Fluorescent Dye
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Neurological Disease
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NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
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- HY-150145A
-
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Nucleoside Antimetabolite/Analog
Fluorescent Dye
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Others
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|
Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP .
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-
- HY-165424
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Fluorescent Dye
Glycosidase
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Cardiovascular Disease
Cancer
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NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .
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-
- HY-150086
-
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CF4
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Fluorescent Dye
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Others
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|
Copper Fluor-4 (CF4) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10 −13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission) .
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- HY-150145
-
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Nucleoside Antimetabolite/Analog
Fluorescent Dye
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Others
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Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .
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- HY-D2962
-
|
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Fluorescent Dye
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Neurological Disease
|
CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease .
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- HY-D3251
-
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Fluorescent Dye
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Cancer
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|
LCP is a fluorescent probe applicable for subcellular localization. LCP responds to polarity changes in the cellular microenvironment via fluorescence resonance energy transfer, emitting blue fluorescence in low-polarity environments and red fluorescence in high-polarity environments. LCP enables dual-color visualization of dynamic changes in lysosomes and cytoplasmic membranes during drug-induced cell apoptosis, and monitors cell viability through localization and emission color changes. LCP can be used in cancer research .
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- HY-D3250
-
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Fluorescent Dye
NO Synthase
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Cardiovascular Disease
|
|
PYSNO is a lysosome-targeted fluorescent probe based on a pyridazinone skeleton (λem=515-565 nm, λex=405 nm) that can be used to track nitric oxide (NO) production in vivo. PYSNO exhibits a rapid, highly sensitive and highly selective "turn-on" response to endogenous and exogenous NO by blocking photoinduced electron transfer and regulating radiative decay rates. PYSNO enables precise in vivo monitoring in a mouse model of myocardial fibrosis and can be applied to the research of related diseases .
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- HY-158616
-
|
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Fluorescent Dye
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Others
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4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.
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- HY-D2992
-
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Fluorescent Dye
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Cancer
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|
KSA02 is a two-dimensional intelligent fluorescent probe. KSA02 not only detects the activity of the aging-related β-galactosidase (SA-β-gal), but also can simultaneously sense the pH value changes of the lysosomal microenvironment where SA-β-gal is located. KSA02 can distinguish between aging and cancer, track the aging process, and evaluate the efficacy of anti-aging agents. KSA02 can be used for the study of aging biology .
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- HY-D3172
-
|
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Fluorescent Dye
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Metabolic Disease
|
|
BD-105 is a glucagon-binding fluorescent probe with a Ka value of 13.3 μM. BD-105 exhibits changes in fluorescence intensity upon interaction with glucagon, and colocalizes with glucagon in cells and tissues. BD-105 is a selective cell stain that labels glucagon-secreting cells without staining insulin-secreting cells or non-endocrine control cells. BD-105 serves as an imaging reagent for glucagon in live cells and tissues .
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- HY-D3168
-
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Fluorescent Dye
Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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|
PCL-2 is a reactive oxygen species-responsive fluorescent probe that shows almost no response to biologically relevant reactive oxygen species other than hydrogen peroxide. PCL-2 reacts with hydrogen peroxide to release 6-hydroxy-2-cyanobenzothiazole. PCL-2 can be used for chemoselective imaging of hydrogen peroxide in in vitro models and acute inflammation mouse models. PCL-2 is applicable to studies related to acute inflammation .
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-
- HY-128676
-
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H-L-Lys(Poc)-OH hydrochloride
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Amino Acid Derivatives
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Cancer
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|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D3189
-
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Fluorescent Dye
PSMA
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Cancer
|
|
5GluAF-2MeTG is an activatable fluorescent probe targeting the glutamate carboxypeptidase (CP) activity of PSMA (Ex/Em=490/500-600 nm). After being hydrolyzed by PSMA, 5GluAF-2MeTG releases a cell membrane-permeable fluorescent product, and achieves fluorescence activation by disrupting donor-excited photoinduced electron transfer (d-PeT). 5GluAF-2MeTG enables fluorescence imaging of live PSMA-expressing prostate cancer cells in vitro and visualizes the carboxypeptidase activity of PSMA. 5GluAF-2MeTG can be used to detect prostate cancer regions in preclinical excised tissue specimens .
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- HY-153006
-
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DCFH2
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Biochemical Assay Reagents
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Others
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2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). The fluorescence intensity of DCF is positively correlated with the ROS concentration. 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO -, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. It is suitable for oxidative stress analysis in in vitro cell models and in vivo targeted delivery (such as liver-targeted liposomes) .
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-
- HY-D3190
-
|
|
Fluorescent Dye
Apoptosis
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Inflammation/Immunology
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|
BODIPY-DOX is a conjugate composed of BODIPY and Doxorubicin (HY-15142A), as well as a pH-activated fluorescent probe for M1 macrophages and an apoptosis inducer. BODIPY-DOX undergoes pH-induced hydrazone bond cleavage in acidic M1 macrophage phagosomes, thereby releasing cytotoxic Doxorubicin (Dox) and inhibiting the function of pro-inflammatory M1 macrophages. BODIPY-DOX highly selectively inhibits the production of relevant pro-inflammatory cytokines by mouse and human monocyte-derived M1 macrophages, while exerting minimal effects on M2 or unactivated macrophages. Therefore, BODIPY-DOX enables simultaneous fluorescent tracing, differentiation and elimination of specific macrophage subsets, and exhibits the potential to regulate tissue regeneration in zebrafish models .
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- HY-N16571
-
|
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Fluorescent Dye
Endogenous Metabolite
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Others
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|
Marionol is a type of flavonol compound and belongs to the secondary metabolites of plants. Marionol exhibits significant specificity towards Cu²⁺ and possesses the characteristic of intramolecular proton transfer in excited state (ESIPT), enabling it to generate strong fluorescence upon excitation by ultraviolet light. The maximum excitation/emission wavelengths are 350 nm and 510 nm (depending on the solvent), respectively. Marionol can be used as a fluorescence probe for Cu²⁺ .
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-
- HY-D3209
-
|
|
Fluorescent Dye
Quinone Reductase
|
Cancer
|
|
NIR-ASM is a near-infrared fluorescent probe that can cross cell membranes and be activated by NQO1. NIR-ASM can distinguish NQO1-expressing cancer cells from normal cells via fluorescence microscopy and flow cytometry. NIR-ASM generates near-infrared fluorescence with a high signal-to-noise ratio in tumor models with NQO1 activity, enabling the detection of endogenous NQO1 activity in vivo. NIR-ASM is applicable to the research of lung cancer and breast cancer .
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-
- HY-P2031
-
|
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Arp2/3 Complex
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Others
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|
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
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- HY-D2982
-
|
|
Fluorescent Dye
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Infection
|
|
BTP9-Neu5Ac is a fluorescent imaging probe specifically designed for detecting the neuraminidase (NA) sialidase activity of influenza viruses. BTP9-Neu5Ac can visualize the intracellular Golgi localization of the viral NA activity. BTP9-Neu5Ac can be used for precise and temporal monitoring of the key enzyme activities during the viral life cycle .
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-
- HY-D3224
-
|
|
Fluorescent Dye
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Neurological Disease
|
|
HCP is a two-photon fluorescent probe capable of crossing the blood-brain barrier, which is specifically designed for real-time detection of hypochlorous acid (HClO/ClO -) produced by myeloperoxidase (MPO). Chlorination of the quinoline skeleton of HCP generates HCP-Cl, which eliminates intramolecular charge transfer (ICT) quenching and thereby produces fluorescence. HCP is suitable for in vivo dynamic imaging of HClO in the brains of epileptic mice and high-throughput screening of antiepileptic drugs (HCP-Cl: Ex/Em = 800 nm/495 nm) .
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- HY-D2942
-
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Fluorescent Dye
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Others
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BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .
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-
- HY-D3174
-
|
|
Fluorescent Dye
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Metabolic Disease
Inflammation/Immunology
|
|
PiF is a fluorescent probe with high specificity for pancreatic β-cells (Ex/Em = 535 nm/565 nm), and its fluorescence signal increases significantly with elevated insulin concentrations in in vitro experiments. PiF enables visualization of rat and human islets transplanted via the portal vein in mouse livers with low liver background signals. The fluorine atom of PiF can be replaced by radioactive 18F to prepare a PET tracer. PiF can be used for research on type 1 diabetes .
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-
- HY-D3211
-
|
|
Fluorescent Dye
Apoptosis
Autophagy
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Cancer
|
|
HJTA is a selective, pH/GSH dual-responsive Fluorescent probe and anticancer agent. HJTA selectively undergoes an enzymatic reaction with GSTπ. HJTA induces Apoptosis and Autophagy by regulating the expression of apoptotic and autophagic proteins. HJTA exhibits pH- and GSH-dual-responsive fluorescence in tumor cells. HJTA selectively illuminates tumor tissues, enabling precise in situ visualization of colon tumors. HJTA exerts anticancer effects against colon cancer. HJTA can be used for colon cancer research .
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-
- HY-D0961
-
|
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Fluorescent Dye
Wnt
β-catenin
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Gallocyanine chloride is a synthetic blue dyestuff that can be used as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies. Gallocyanine chloride inhibits DKK1/LRP6 interaction (IC50=6.38 μM), activates Wnt signaling pathway, and causes β-catenin accumulation. Gallocyanine chloride exhibits anti-metastasis, anti-inflammatory and anti-fibrosis activities. Gallocyanine chloride can be used as a fluorescent probe for detection of superoxide anion radicals .
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- HY-150175
-
|
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Fluorescent Dye
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Inflammation/Immunology
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|
HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
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- HY-Y1309S1
-
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Furro ER-d7; NSC 9586-d7; Nako TRB-d7
|
Isotope-Labeled Compounds
Endogenous Metabolite
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Others
|
|
1-Naphthol-d7 (Furro ER-d7) is the deuterium labeled Naphthol (HY-Y1309). 1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media .
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-
- HY-W024271
-
|
9-Formyl-8-hydroxyjulolidine
|
Fluorescent Dye
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Cardiovascular Disease
Neurological Disease
|
|
8-Hydroxyjulolidine-9-carboxaldehyde (9-Formyl-8-hydroxyjulolidine) is a highly selective fluorescent probe for hydrogen sulfide (S 2−) and silicate (SiO3 2−). 8-Hydroxyjulolidine-9-carboxaldehyde operates via a mechanism of blocking intramolecular charge transfer (ICT), exhibiting significant fluorescence enhancement in the presence of weak acid ions. 8-Hydroxyjulolidine-9-carboxaldehyde is promising for research of fluorescence imaging of hydrogen sulfide within living cells .
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-
- HY-D3269
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|
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Fluorescent Dye
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Others
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Mito-Cu (II) is a mitochondria-targeted fluorescent probe (Ex/Em = 370/450 nM). Mito-Cu (II) specifically accumulates in mitochondria of living cells and enables real-time detection of exogenous Cu 2+ within mitochondria of living cells. Mito-Cu (II) achieves "on-off-on" fluorescence switching through sequential exposure to Cu 2+ and ethylenediaminetetraacetic acid (EDTA) (HY-Y0682). Its fluorescence is quenched after forming a 1:1 complex with Cu 2+, and the fluorescence recovers when Cu 2+ is chelated by EDTA .
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-
- HY-DY1104
-
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CF4 (solution)
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Fluorescent Dye
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Others
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Copper Fluor-4 (solution) (CF4 (solution)) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 solution has high copper selectivity with a Kd value of 2.9×10 ?13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 solution is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission) .
Solvent and concentration: DMSO: 5 mM
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- HY-D2998
-
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Fluorescent Dye
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Others
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ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes .
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-
- HY-W017232
-
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p-Quinanisole
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Biochemical Assay Reagents
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Others
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6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
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- HY-128868B
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Biochemical Assay Reagents
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Others
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FITC-Dextran (MW 3000-5000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 3000-5000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 3000-5000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Storage: protect from light.
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- HY-156404
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PM-1
2 Publications Verification
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Fluorescent Dye
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Others
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PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins .
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- HY-I0259
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Fluorescent Dye
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Others
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8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .
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- HY-D2963
-
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Fluorescent Dye
Amyloid-β
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Neurological Disease
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|
R-MA-SLM is an Aβ-targeted and blood-brain barrier-permeable ratiometric H2O2-responsive fluorescent probe. When excited at 490 nm, the fluorescence intensity of the R-MA-SLM gradually decreases at 574 nm, while the emission intensity gradually increases at 661 nm. R-MA-SLM can detect and exhibits a ratiometric response to Aβ-induced endogenous H2O2. R-MA-SLM can be used in the research of Alzheimer's disease .
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- HY-D2968
-
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Fluorescent Dye
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Neurological Disease
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DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models .
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- HY-D0155
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Fluorescent Dye
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Others
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Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn 2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis .
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- HY-D2365
-
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Fluorescent Dye
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Others
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QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
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- HY-158082B
-
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Tetramethyl rhodamine isothiocyanate glucan, MW 40000
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Fluorescent Dye
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Others
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TRITC-dextran (Tetramethyl rhodamine isothiocyanate glucan), MW 40000 is a TRITC (HY-D0791)-labeled neutral 40 kDa fluorescent polysaccharide probe. TRITC-dextran, MW 40000 forms a membrane layer on the surface of protocells composed of protamine/folate condensates, and is used to assess membrane fluidity via fluorescence recovery after photobleaching. TRITC-dextran, MW 40000 can also be used to evaluate the anti-bacterial invasion ability and colloidal stability of coated condensates, as well as analyze the permeability of vascular and lymphatic endothelial cell layers .
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- HY-D2907
-
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DBCO-Cy5; Cyanine5 dibenzocyclooctyne
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Fluorescent Dye
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Others
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Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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- HY-D1721
-
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Fluorescent Dye
Thrombin
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Others
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Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .
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- HY-126220
-
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Fluorescent Dye
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Others
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KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
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- HY-D2953
-
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CLIP-CPY
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Fluorescent Dye
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Others
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BC-CPY is a CLIP-tagged probe based on the pyridine-benzoanthrone (CPY) fluorophore (Ex/Em: 580 nm/610 nm). BC-CPY has excellent cell membrane permeability, enabling deep imaging, low phototoxicity and high signal-to-noise ratio. BC-CPY can be used for super-resolution microscopy imaging of living cells .
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- HY-D1809
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Fluorescent Dye
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Others
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Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
Product Concentration: 0.8 mg/mL
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- HY-D3195
-
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Fluorescent Dye
Bacterial
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Infection
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CDr15 is a deep-red fluorescent probe (Ex=733 nm) that can selectively intercalate into and label bacterial extracellular DNA (eDNA). CDr15 exhibits extremely high specificity for biofilm imaging and cannot effectively bind to mammalian nuclear DNA. CDr15 enables real-time visualization of the microcolony structure and developmental process of three-dimensional *Pseudomonas aeruginosa* biofilms, and accurately localizes biofilm-forming regions of microorganisms in a mouse corneal infection model. With low background interference signals, CDr15 serves as an ideal diagnostic tool for research fields including bacterial biofilms and corneal infections .
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- HY-126220A
-
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Fluorescent Dye
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Others
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KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
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- HY-D1807
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Fluorescent Dye
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Others
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Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1808
-
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Fluorescent Dye
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Others
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Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1804
-
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Fluorescent Dye
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Others
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Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
Product Concentration: 0.8 mg/mL
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- HY-149203A
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Fluorescent Dye
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Others
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MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO -, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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- HY-D3170
-
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Fluorescent Dye
γ-Glutamyl Transferase (GGT)
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Inflammation/Immunology
|
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C-HBrO-GGT is a sequence-activated two-photon fluorescent probe. C-HBrO-GGT exhibits sequential fluorescence activation properties: it generates fluorescence in response to hypobromous acid only after being hydrolytically activated by γ-glutamyl transpeptidase. C-HBrO-GGT enables verification of the voltage-gated chloride channel (CLC-1)-HBrO-catalase (CAT)-GGT signaling pathway at the cellular level. C-HBrO-GGT can serve as a tool to indicate the precise location of mature atherosclerotic plaques and provide early warning of plaque formation. C-HBrO-GGT is applicable to relevant research on atherosclerosis .
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- HY-D3415
-
|
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Fluorescent Dye
G-quadruplex
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Cancer
|
|
TOR-G4 is a Fluorescent probe that binds to G-quadruplex (G4) nucleic acid structures. TOR-G4 exhibits a unique fluorescence lifetime when bound to G4 compared to other structures, enabling sensitive discrimination between G4-bound and non-G4-bound states. TOR-G4 mainly colocalizes with RNA in the cytoplasm and nucleolus. TOR-G4 can be used to investigate the roles of RNA G4 in cells. TOR-G4 shows cytotoxicity against osteosarcoma cells .
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- HY-D1805
-
|
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Fluorescent Dye
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Others
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Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1806
-
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Fluorescent Dye
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Others
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Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
Product Concentration: 0.8 mg/mL
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- HY-W001952
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Fluorescent Dye
Drug Intermediate
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Others
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6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria .
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- HY-P11263
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|
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iGluR
|
Neurological Disease
|
|
AVLX-144 is a highly potent inhibitor of postsynaptic density protein 95 (PSD-95). AVLX-144 can be used as a template to develop imaging probes for postsynaptic density (PSD) molecules, and can be labeled with fluorine-18 (¹⁸F) or tritium (³H) to visualize PSD-95 in vivo. AVLX-144 can be utilized for the study of Parkinson's disease .
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- HY-D2924
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|
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Fluorescent Dye
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Others
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CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .
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- HY-126823
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|
PGSK diacetate (5/6-mixture)
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Fluorescent Dye
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Others
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Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe 2+, Cd 2+, Co 2+, Ni 2+, Zn 2+, etc. Phen green SK (PGSK) diacetate chelates Fe 2+, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively .
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- HY-DY1003
-
|
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Fluorescent Dye
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Others
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JC-1 (CBIC2) (solution) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm) ; When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
Solvent and concentration: DMSO: 1.5 mM
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-
- HY-D3179
-
|
|
Fluorescent Dye
BCRP
|
Neurological Disease
|
|
CDg13 is a fluorescent probe that specifically detects living neural stem/progenitor cells. CDg13 localizes to the endoplasmic reticulum via its dihexyl moiety, with no interaction with endoplasmic reticulum biomolecules. CDg13 undergoes selective efflux by active ABCG2 transporters, with increased intracellular accumulation following ABCG2 inhibition or knockdown. CDg13 isolates and enriches self-renewable neural stem/progenitor cells from embryonic mouse brain tissue, stains neural stem/progenitor cells brightly, and sorts ABCG2low cell populations from heterogeneous populations . (Ex/Em = 520/553 nm)
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-
- HY-W073013
-
|
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MOFs
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Others
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|
5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II), commonly known as CoTPP or cobalt porphyrin, is a coordination compound. 5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II) is widely used in various fields such as catalysis, sensing, and organic electronics because of its unique electronic and optical properties. An efficient catalyst for reactions including oxidation, reduction, and CH bond activation, moreover, it has been used as a fluorescent probe for detecting oxygen content in biological systems and as an active material in organic solar cells.
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-
- HY-W011696
-
|
cis-1-Amino-9-octadecene, 80-90%
|
Environmental Pollutants
Biochemical Assay Reagents
|
Cancer
|
|
Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a multifunctional reagent used for metal ion coordination and nanoparticle surface modification, and acts as a solvent, surfactant and reducing agent in the synthesis of metal oxide nanoparticles. Oleylamine, 80-90% regulates nanoparticle morphology, magnetization intensity and water proton relaxation rate via thiol-ene "click" reaction, and enhances the colloidal stability of nanoparticles in organic reagents. Oleylamine, 80-90% is mainly used in research and applications in fields such as nanomaterial synthesis, biomedical imaging (MRI contrast agents, fluorescent probes), cancer cell targeting and drug delivery .
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-
- HY-D3192
-
|
|
Fluorescent Dye
Bacterial
Amyloid-β
|
Infection
|
|
CDy11 is a fluorescent probe and amyloid-binding dye (λex=590 nm; λem=612 nm), with a Ka of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .
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-
- HY-NP0144
-
|
WGA (Fluorescein)
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Fluorescent Dye
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Others
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Succinylated Wheat Germ Agglutinin (Fluorescein) (WGA (Fluorescein)) is a fluorescent lectin that acts as a probe to specifically bind biomolecules. Succinylated Wheat Germ Agglutinin (Fluorescein) binds to cell surface glycoconjugates containing N-acetylglucosamine. Succinylated Wheat Germ Agglutinin (Fluorescein) is a selective agglutinating agent targeting specific red blood cells, thymocytes, splenocytes and lymphocytes. Succinylated Wheat Germ Agglutinin (Fluorescein) binds to fibroblasts and lymphocytes via dual binding sites in a temperature-dependent, saturable manner. Succinylated Wheat Germ Agglutinin (Fluorescein) can be used for quantitative studies of cell surface receptor glycoconjugates (Ex=495 nm, Em=515 nm) .
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- HY-N16308
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|
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Fluorescent Dye
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Others
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ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes .
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-
- HY-D1078
-
|
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Fluorescent Dye
Reactive Oxygen Species (ROS)
P-glycoprotein
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Others
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5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC4 for MRP2 binding sites and inhibits MRP2-mediated LTC4 transport (Ex/Em = 496/525 nm) .
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-
- HY-148958
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-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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-
- HY-D3191
-
|
|
Fluorescent Dye
Aminopeptidase
Monoamine Oxidase
|
Infection
Metabolic Disease
|
|
L&M-D-MR is a highly specific fluorescent "AND" logic probe with response moieties for leucine aminopeptidase (LAP) and monoamine oxidase (MAO). The coexistence of both LAP and MAO is required for L&M-D-MR to trigger intramolecular cyclization, release fluorophores and activate fluorescence. In the presence of only a single enzyme, L&M-D-MR generates only an extremely weak signal. L&M-D-MR enables bioimaging in living cells and mouse models, and can effectively distinguish different subtypes of liver diseases via blood samples or test strips. L&M-D-MR is widely used in studies related to liver cirrhosis, hepatitis B and drug-induced liver injury .
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-
- HY-D3181
-
|
|
Fluorescent Dye
Caspase
|
Cancer
|
|
CyGbPF is a granzyme B-specific near-infrared fluorescent probe. CyGbPF can be cleaved by granzyme B to remove the peptide cage group, restoring near-infrared fluorescence. CyGbPF passively accumulates in mouse tumors, and its activated fluorescence correlates with granzyme B expression, CD8 + cytotoxic T lymphocyte populations, and CD4 + helper T lymphocyte populations in tumor tissues. CyGbPF is efficiently cleared by the kidneys, enabling the assessment of immune activation via optical urine analysis. CyGbPF allows real-time non-invasive evaluation of cancer immunotherapeutic efficacy in living animals. CyGbPF can be used in research on cancers such as breast cancer. Excitation wavelength/emission wavelength: approximately 658 nm/approximately 717 nm .
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-
- HY-D3153
-
|
|
Apoptosis
Caspase
Microtubule/Tubulin
|
Inflammation/Immunology
|
|
PbQ is a tubulin inhibitor (with an IC50 of 5 μM against goat tubulin) and a fluorescent probe for cuprous ions Cu (I). PbQ can penetrate the membrane of peripheral blood mononuclear cells, form a stable 1:1 complex with Cu + ions, and exhibits low toxicity and good biocompatibility toward macrophage cell lines. In addition, PbQ promotes tubulin degradation and disrupts the microtubule network in lung epithelial cells without affecting actin. PbQ also possesses genotoxicity by forming DNA base adducts, and it can activate caspase-3 and apoptosis-related genes, induce loss of mitochondrial membrane potential, and trigger cell apoptosis. PbQ can be used in studies related to chronic obstructive pulmonary disease .
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- HY-160116
-
|
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Radionuclide-Drug Conjugates (RDCs)
Fluorescent Dye
α-synuclein
|
Neurological Disease
|
|
α-Synuclein aggregate binder 1 (Compound C05-05) is a specific binder for α-synuclein aggregates and can inhibit α-synuclein aggregation. α-Synuclein aggregate binder 1 can be used as a fluorescent probe (excitation wavelength 900 nm, detection wavelength 500-550 nm) for optical imaging, and can also inhibit α-synuclein fibril formation by blocking the aggregation process. α-Synuclein aggregate binder 1 can be used for positron emission tomography (PET) imaging after being labeled with 18F. α-Synuclein aggregate binder 1 can be used for visual diagnosis of brain lesions and mechanism research of neurodegenerative diseases such as Parkinson's disease and Lewy body dementia .
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-
- HY-15558
-
|
bisBenzimide H 33258; H 33258
|
Fluorescent Dye
DNA Stain
DNA Alkylator/Crosslinker
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Others
|
|
Hoechst 33258 is a blue to blue-green fluorescent live cell dye that can label DNA. Hoechst 33258 can specifically bind to the minor groove of DNA (and tends to bind to A/T-rich DNA), resulting in a significant increase in fluorescence intensity. Hoechst 33258 can cross the cell membrane and cause changes in DNA structure, such as G2/M phase arrest. Hoechst 33258 can bind to live or fixed cells, and the fluorescence intensity increases with increasing solution pH. As a DNA-specific probe, Hoechst 33258 can be used to detect DNA content, analyze cell cycle, etc. The excitation wavelength of Hoechst 33258 is 350-365 nm, and the emission wavelength is 460-490 nm .
|
-
- HY-D3186
-
|
|
Fluorescent Dye
Glycosidase
|
Cancer
|
|
HMRef-βGal is a fluorescent probe and a substrate responsive to β-galactosidase (β-galactosidase) (Ex/Em=498 nm/505-600 nm). After being cleaved by β-galactosidase, HMRef-βGal triggers significant fluorescence enhancement via intramolecular spirocyclic function regulation. HMRef-βGal generates bright fluorescence in cancer cells with elevated β-galactosidase activity, enabling visualization of tiny peritoneal metastases in mouse models. HMRef-βGal exhibits low in vitro cytotoxicity and low acute in vivo toxicity in mice. HMRef-βGal can be used for preclinical fluorescence-guided diagnosis and cytoreductive surgery of peritoneal metastases, including compatibility with real-time naked-eye detection and endoscopic imaging, as well as for studies related to peritoneal metastases of ovarian cancer .
|
-
- HY-W020012
-
|
22-NBD Cholesterol
|
Fluorescent Dye
|
Metabolic Disease
|
|
Fluoresterol (22-NBD Cholesterol) is a cholesterol-specific fluorescent probe with cholesterol-mimicking binding properties. Fluoresterol is ineffective orally and does not cross the blood-brain barrier. Fluoresterol specifically binds to cholesterol transport-related proteins (such as ABCA1 and ABCG1) and is primarily used in cholesterol metabolism research, particularly for the visualization and quantitative analysis of cholesterol absorption, efflux, intracellular transport efficiency, and reverse cholesterol transport (RCT) processes. The commonly used concentration of Fluoresterol in in vitro experiments is 0.1-10 μM, and the commonly used dose in in vivo experiments is 5-20 mg/kg (gavage or intraperitoneal injection), with excitation/emission wavelengths of 472/540 nm. Fluoresterol can be applied to the study of cholesterol metabolism mechanisms related to hyperlipidemia, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD) .
|
-
- HY-D3210
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
DCM-KPV is a fluorescent probe targeting the human intestinal oligopeptide transporter PEPT1/SLC15A1 receptor (λex=480 nm, λem=620-670 nm). DCM-KPV specifically binds to PepT1 via its KPV domain and mediates receptor-targeted internalization, thus effectively accumulating in the cytoplasm and nucleus of cells overexpressing this receptor. DCM-KPV has the advantages of long emission wavelength, high emission efficiency, low photobleaching, and negligible cytotoxicity. DCM-KPV maintains stable fluorescence intensity under continuous illumination, exhibiting extremely high live cell compatibility. DCM-KPV can specifically accumulate at colonic inflammatory sites through the intestinal mucosa, enabling direct non-invasive visual differentiation between chronic and acute ulcerative colitis groups and the normal group .
|
-
- HY-108910
-
|
EC 3.4.21.1; Chymotrypsin A
|
Toll-like Receptor (TLR)
NF-κB
MMP
|
Others
Inflammation/Immunology
|
|
Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin downregulates the TLR4/NF-κB signaling pathway, inhibiting the release of inflammatory factors, reducing cell infiltration and tissue damage. It also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54) and can be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions. It can be used in research on diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin can be used in studies of inflammation, edema, and expectoration .
|
-
- HY-108910A
-
|
EC 3.4.21.1 (MS grade); Chymotrypsin A (MS grade)
|
Toll-like Receptor (TLR)
NF-κB
MMP
|
Others
Inflammation/Immunology
|
|
Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) (MS grade) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin (MS grade) downregulates the TLR4/NF-κB signaling pathway, inhibits the release of inflammatory factors, reduces cell infiltration and tissue damage, and also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54). It can also be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin (MS grade) has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions, and can be used in the research of diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin (MS grade) can be used in studies of inflammation, edema, and expectoration .
|
-
- HY-181453
-
|
2’-O-Benzyl-3’-MANT-GTP sodium
|
Drug Derivative
Fluorescent Dye
|
Others
|
|
2'-O-Benzyl-3'-O-(N'-methylanthraniloyl) guanosine-5'-O-triphosphate sodium (Mant-GTP R=CH3, B=Gua) (2'-O-Benzyl-3'-MANT-GTP sodium) is a methylanthraniloyl derivative of GTP (HY-113225). Methylanthraniloyl-GTP exhibits fluorescent properties (λmax: 442 nm in water; 432 nm in ethanol) .
|
-
- HY-W327027
-
|
|
Fluorescent Dye
|
Others
|
|
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one (Compound 1) is a fluorescent probe for the detection of hydrogen sulfide (H2S). 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has a low detection limit (4×10 -6 mol/L), good selectivity and high sensitivity. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one shows almost no cytotoxicity at concentrations of 150 µg/mL. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has the excitation peak of 331 nm, and the emission peak about 385 nm in DMSO solvent. Upon the addition of increasing amounts of HS -, the fluorescence intensity increases obviously at about 392 nm .
|
-
- HY-W783351
-
|
Coppersensor 790 acetoxymethyl ester
|
Fluorescent Dye
|
Metabolic Disease
|
|
CS790AM (Coppersensor 790 acetoxymethyl ester) is a cell-permeable, Cu +-targeted near-infrared fluorescent probe (λabs=760 nm, λem=790 nm) applicable to live cells. CS790AM can cross lipophilic cell membranes, and is converted into negatively charged CS790 under the action of intracellular esterases to be retained, thus enabling highly sensitive, reversible "turn-on" detection of labile Cu + pools in live cells and mice. CS790AM possesses excellent biocompatibility and selectivity, avoids interference from other metal ions, shows no obvious toxicity, and can be rapidly cleared. CS790AM allows long-term longitudinal monitoring of individual mice, visualizes copper levels in internal organs and isolated livers, and effectively evaluates abnormal copper accumulation in Wilson's disease models (Atp7b -/-) as well as dynamic changes after chelator treatment. CS790AM can be used for research on Wilson's disease and related copper metabolic disorders .
|
-
- HY-112624I
-
|
Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
|
Bacterial
|
Others
|
|
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-D1269
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups . Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm).
|
-
- HY-151701
-
|
|
Fluorescent Dye
|
Others
|
|
DiSulfo-Cy5 alkyne is a fluorescent dye can be used as a click chemistry reagent .
|
-
- HY-133424A
-
|
|
Fluorescent Dye
|
Others
|
|
Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
|
-
- HY-113053F
-
|
PGA1-biotin
|
Drug Derivative
|
Infection
|
|
Prostaglandin A1-biotin (PGA1-biotin) is a biotin-labeled Prostaglandin A1 (HY-113053). Prostaglandin A1-biotin can be found in the culture filtrate of rhizobia, and the culture filtrate containing this compound exhibits significant antiviral activity .
|
-
- HY-D1029A
-
-
- HY-D2593
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-PEG2000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
|
-
- HY-D1030
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein Biotin is a fluorescent modulator with avidin and streptavidin binding activity. Fluorescein Biotin binds to the biotin-binding sites of avidin and streptavidin, and this binding induces significant fluorescence quenching .
|
-
- HY-D2025
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 biotin is a biotin derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D1925
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D1361
-
|
|
Fluorescent Dye
|
Others
|
|
Alkyne cyanine dye 718 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2852
-
|
|
Fluorescent Dye
|
Others
|
|
Heparin-Cy7 is a fluorescent dye composed of CY7 (HY-D0825) and heparin. Heparin-CY7 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 740/770 nm).
|
-
- HY-D0226R
-
|
1,4-Dihydroxyanthraquinone (Standard)
|
Reference Standards
DNA/RNA Synthesis
Fungal
|
Infection
Cancer
|
|
Quinizarin (Standard) is the analytical standard of Quinizarin. This product is intended for research and analytical applications. Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .
|
-
- HY-W998662
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin 343 X carboxylic acid is a blue emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).
|
-
- HY-D1027
-
|
Monodansyl cadaverine
|
Autophagy
|
Others
|
|
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
|
-
- HY-D2661
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 100000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
-
- HY-155324
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D2191
-
-
- HY-D2342
-
|
|
Fluorescent Dye
|
Infection
|
|
SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells .
|
-
- HY-W800809
-
|
|
Fluorescent Dye
|
Others
|
|
FAM DBCO, 6-isomer represents a variant of a time-honored fluorescent dye and featuring a terminal DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy.
|
-
- HY-D1485
-
|
|
Bacterial
|
Others
|
|
3,3'-Diethylthiacyanine iodide is a cyanine fluorescent dye. 3,3'-Diethylthiacyanine iodide manifestes a pronounced affinity for bacterial cells .
|
-
- HY-D2537
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG2000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-100041
-
|
Monobromobimane
|
Fluorescent Dye
|
Others
|
|
Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
|
-
- HY-137296
-
|
|
Fluorescent Dye
|
Others
|
|
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .
|
-
- HY-D1683A
-
-
- HY-D2758
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA DBCO, 5-isomer is a derivative of tetramethylrhodamine (TMR, TAMRA) containing a cyclooctyne moiety (dibenzocyclooctyne, DBCO). Pure 5-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction (SPAAC)). TAMRA DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups.
|
-
- HY-138111
-
|
p-Nitopheyl β-D-cellotetaoside
|
Fluorescent Dye
|
Others
|
|
4-Nitrophenyl β-D-cellotetraoside (p-Nitopheyl β-D-cellotetaoside) is a small molecule cellulose mimetic consisting of a tetramer of D-glucose units linked by β-1-4 glycosidic bonds. The fragmentation pattern of 4-Nitrophenyl β-D-cellotetraoside after enzymatic hydrolysis can be analyzed by TLC or by the release of 4-nitrophenol, which has a strong absorbance at 395 nm in alkaline solutions. 4-Nitrophenyl β-D-cellotetraoside can be used in cellulose degradation studies to determine the specificity of cellulases .
|
-
- HY-137844
-
|
Leu-AMC hydrochloride
|
Fluorescent Dye
|
Others
|
|
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .
|
-
- HY-W273413
-
|
NBD-H
|
Fluorescent Dye
|
Cancer
|
|
4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is a fluorescent reagent used for protein labeling .
|
-
- HY-D2169
-
|
|
Fluorescent Dye
|
Others
|
|
AF 568 carboxylic acid is the non-reactive form of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne forms stable covalent bonds by reacting carboxylic acid groups with molecules bearing amino groups. Copper-catalyzed azide-alkyne cycloaddition (CuAAc) can occur with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups .
|
-
- HY-D2284
-
|
Sphingosine-1-phosphate lyase fluorogenic substrate
|
Fluorescent Dye
|
Cancer
|
|
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .
|
-
- HY-D1916A
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 TEA is a highly hydrophilic fluorescent dye used to label the outermost position of the glycan moiety of glycosphingolipids to retain the biophysical and biochemical properties of native glycosphingolipids .
|
-
- HY-15937
-
|
5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers
|
Fluorescent Dye
|
Others
|
|
5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.
|
-
- HY-D2105
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
|
-
- HY-D2371
-
|
|
Fluorescent Dye
|
Others
|
|
3-BTMD is obtained by COMT enzyme specifically catalyzing the substrate 3-BTD (Ex=390 nm, Em=510 nm) .
|
-
- HY-B1533A
-
|
|
Fluorescent Dye
|
Others
|
|
Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λmax = 571 nm .
|
-
- HY-136248A
-
|
|
Fluorescent Dye
DNA Stain
|
Others
|
|
Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
|
-
- HY-D2838
-
|
|
Fluorescent Dye
|
Others
|
|
mPEG-PEI-Cy5 (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 5000) can be used for fluorescent labeling and imaging .
|
-
- HY-D1983
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
|
-
- HY-D1700
-
|
|
Fluorescent Dye
|
Others
|
|
Mag-indo-1/AM is a cell-permeable fluorescent indicator for Mg 2+ and also for Ca 2+ (Ex=340-390 nm, Em=410-490 nm). Mag-indo-1/AM can be used to determine intracellular Mg 2+ and Ca 2+ concentrations .
|
-
- HY-121930
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
Coumarin 6H, a Coumarin (HY-N0709) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions .
|
-
- HY-D2642
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 10000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-136937
-
|
|
Fluorescent Dye
|
Others
|
|
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-112803
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2).
|
-
- HY-D1260
-
|
PSH-red
|
Fluorescent Dye
|
Neurological Disease
|
|
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .
|
-
- HY-D2911
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
|
-
- HY-D2575
-
|
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
WYneN (compound 10) is a functionalized Wittig-alkyne probe. WYneN exhibits strong reactivity with sulfinic acid dipeptide models, similar to the parent Wittig reagent. WYneN can be used to reveal the function of oxidative modifications on a proteome-wide scale .
|
-
- HY-D2034
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 hydrazid is a hydrazide derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
|
-
- HY-D1317A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine7.5 carboxylic is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D1040
-
|
Cyanine 5.5 carboxylic acid
|
Fluorescent Dye
|
Others
|
|
Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis .
|
-
- HY-DY1017
-
|
|
Antibiotic
Fungal
|
Infection
|
Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718) , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
Solvent and concentration: DMSO: 5 mg/mL
|
-
- HY-DY1060
-
|
|
Proteasome
Fluorescent Dye
|
Others
|
Suc-Leu-Leu-Val-Tyr-AMC (solution) is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
Solvent and concentration: DMSO: 20 mM
|
-
- HY-D2007
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 biotin is a biotin derivative of ATTO 488 with maximum excitation/emission wavelengths: 500/520 nm.
|
-
- HY-B0315A
-
|
Biotin-Cyanocobalamin B12
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is the biotinylated Vitamin B12 (HY-B0315). Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. Biotin-Vitamin B12 can be used in researches on vitamin B12 transport, cellular uptake, targeted delivery, analytical detection, and other areas .
|
-
- HY-D1456
-
|
|
Pyruvate Kinase
|
Cancer
|
|
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .
|
-
- HY-121426
-
-
- HY-D2615
-
|
|
Fluorescent Dye
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Others
|
|
ICG PEG5000 biotin is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em=785/813 nm).
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-
- HY-77962
-
|
|
Biochemical Assay Reagents
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Others
|
|
2-Thiobarbituric acid is a commonly used colorimetric reagent for the detection of malondialdehyde (MDA), a marker of lipid peroxidation. 2-Thiobarbituric acid forms a complex with MDA that can be quantified by colorimetric detection at 532 nm as a measure of lipid peroxidation .
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-
- HY-D1548
-
|
|
Fluorescent Dye
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Others
|
|
1-(Azidomethyl)pyrene is a fluorescent dye . 1-(Azidomethyl)pyrene is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-101888R
-
|
|
Fluorescent Dye
Reference Standards
|
Neurological Disease
|
|
Cresyl Violet acetate (Standard) is the analytical standard of Cresyl Violet acetate (HY-101888). This product is intended for research and analytical applications. Cresyl Violet acetate is a dye, which can be used to stain neurons.
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-
- HY-D2561
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG3400-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-111391R
-
|
Diazoresorcinol sodium (Standard)
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Reference Standards
Bacterial
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Others
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|
Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.
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-
- HY-D1375
-
|
|
Fluorescent Dye
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Others
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|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1307A
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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-
- HY-D2589
-
|
|
Fluorescent Dye
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Others
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
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-
- HY-D0028
-
|
|
Fluorescent Dye
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Others
|
|
6-(4-Acetamido-1,8-naphthalamido)hexanoic acid is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W440303
-
|
HITC
|
Fluorescent Dye
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Others
|
|
1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate (HITC) is a long-wavelength, membrane-potential sensitive dye. It is a slow-response potentiometric fluorophore and has also been used as a laser dye for infrared lasers.
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-
- HY-D2139
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG3-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2699
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
|
-
- HY-D2259
-
|
|
E1/E2/E3 Enzyme
Ligands for E3 Ligase
|
Others
|
|
PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation .
|
-
- HY-D2845C
-
|
|
Fluorescent Dye
|
Others
|
|
4-arm-PEG20000-FITC is a fluorescent dye composed of FITC (HY-66019) and four-arm polyethylene glycol (4-Arm PEG). 4-arm-PEG20000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
-
- HY-D2527
-
-
- HY-DY1071
-
|
|
Fluorescent Dye
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Others
|
pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
Solvent and concentration: DMSO: 10 mM
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-
- HY-D2078
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 amine is an amine derivative of ATTO 665, the maximum excitation/emission wavelength: 663/680 nm.
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-
- HY-W351339
-
|
|
Fluorescent Dye
|
Cancer
|
|
BAPTA-TMFM is a fluorescent chelating indicator used to study the role of cytosolic free calcium.
|
-
- HY-B1025R
-
|
Lanadigenin (Standard)
|
Fluorescent Dye
Reference Standards
|
Inflammation/Immunology
|
|
Digoxigenin (Standard) is the analytical standard of Digoxigenin. This product is intended for research and analytical applications. Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .
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-
- HY-D1675
-
|
|
Fluorescent Dye
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Others
|
|
6-HoeHESIR is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2505
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG1000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG1000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
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-
- HY-D2182
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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-
- HY-D1639
-
|
|
Fluorescent Dye
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Others
|
|
5,5'-Dibromo BAPTA tetrapotassium is a calcium chelator, can be formulated into a buffer with a defined calcium ion concentration. 5,5'-Dibromo BAPTA tetrapotassium can control the concentration of calcium ions inside and outside the cell and can be used in studies of calcium physiological activity .
|
-
- HY-D2104
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-DY1051
-
|
|
Bacterial
Fluorescent Dye
|
Infection
|
Resazurin sodium (Diazoresorcinol sodium) (solution) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
Solvent and Concentration: Sterile water: 10 mM
|
-
- HY-101880R
-
|
10-Acetyl-3,7-dihydroxyphenoxazine (Standard)
|
Fluorescent Dye
Reference Standards
|
Others
|
|
ADHP (Standard) is the analytical standard of ADHP (HY-101880). This product is intended for research and analytical applications. ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
|
-
- HY-D1622
-
|
Cy3-DBCO hexafluorophosphate
|
Fluorescent Dye
|
Others
|
|
Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
|
-
- HY-D1860
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-120959
-
|
|
Fluorescent Dye
Parasite
|
Others
|
|
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
|
-
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D2706
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-D2177
-
|
|
Fluorescent Dye
|
Others
|
|
AF 555 azide is a fluorescent dye and is the azide of AF 555. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 555/565 nm) .
|
-
- HY-141576
-
|
dhCerC6NBD
|
Fluorescent Dye
|
Others
|
|
C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .
|
-
- HY-158739
-
|
|
Fluorescent Dye
|
Cancer
|
|
Rhodamine dithenoyl hydrazide (probe 1) possesses excellent recognition and selectivity for Fe 3+ ion. Rhodamine dithenoyl hydrazide exhibits Excitation/Emission maxima of 543/550-700 nm, respectively .
|
-
- HY-W040230
-
|
|
Fluorescent Dye
|
Others
|
|
Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys 34 .
|
-
- HY-D2771
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
|
-
- HY-D1890
-
|
|
Fluorescent Dye
|
Others
|
|
N-(2-Aminooxyethyl)-7-DCCAm (Compound 7) is a fluorescent dye, and can be used for protein labeling .
|
-
- HY-D1950
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .
|
-
- HY-D1524A
-
|
1,8-EDNAS sodium
|
Fluorescent Dye
|
Others
|
|
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2186
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material .
|
-
- HY-135414B
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-151757
-
|
|
Fluorescent Dye
|
Others
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
|
-
- HY-112624F
-
|
|
Fluorescent Dye
|
Others
|
|
CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
|
-
- HY-DY1005
-
|
|
Autophagy
|
Others
|
Hoechst 33342 trihydrochloride (solution) is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
Solvent and Concentration: Sterile water: 10 mg/mL
|
-
- HY-D2155
-
|
|
Fluorescent Dye
|
Others
|
|
Texas red-X 4-succinimidyl ester is a derivative of Texas Red (HY-101878), an amphoteric rhodamine red fluorescent dye. Texas Red is widely used to study neuronal morphology and as a cell type-selective fluorescent marker for astrocytes, both in vivo and in slice preparations.
|
-
- HY-D1309
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-D1779
-
-
- HY-D2630
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
-
- HY-D2704
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA biotin (MW 10000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
|
-
- HY-D2480
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
BODIPY 480/508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of Cholesteryl Linoleate (HY-W010697). BODIPY 480/508-cholesteryl linoleate has been used to monitor cholesterol trafficking in isolated human monocyte-derived macrophages (Ex/Em=480/508 nm).
|
-
- HY-P2628
-
|
|
Fluorescent Dye
|
Others
|
|
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K + deprivation-induced apoptosis of cerebellar granule neurons .
|
-
- HY-D0102
-
|
ABD-F
|
Fluorescent Dye
|
Others
|
|
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols (Ex/Em: 380/510 nm). 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor .
|
-
- HY-D2752
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 dimethyl is a free non-activated dye and can be used as a non-reactive fluorophore for experiment controls and instrument calibration. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.
|
-
- HY-129953F
-
|
PGF2α-biotin
|
Biochemical Assay Reagents
Prostaglandin Receptor
|
Others
|
|
Prostaglandin F2α-biotin (PGF2α-biotin) is a biotinylated form of Prostaglandin F2α (HY-12956). Prostaglandin F2α-biotin can be used in the study of the mechanism of action of prostaglandins. In addition, Prostaglandin F2α-biotin can be detected in the ethanolic extract of Hawm Gra Dang Ngah rice .
|
-
- HY-D2919
-
|
|
Fluorescent Dye
|
Infection
|
|
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .
|
-
- HY-D0259R
-
|
Erythrosin extra bluish (Standard)
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Erythrosine B (Standard) is the analytical standard of Erythrosine B. This product is intended for research and analytical applications. Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
|
-
- HY-D2567
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG5000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D1451
-
|
|
Fluorescent Dye
|
Others
|
|
PKH 26 is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm), which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies .
|
-
- HY-D2150
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D1619
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .
|
-
- HY-D1556
-
|
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium
|
Fluorescent Dye
|
Cancer
|
|
18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .
|
-
- HY-D1382
-
|
|
Fluorescent Dye
|
Others
|
|
BrIR2 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-DY1085
-
|
5(6)-Carboxytetramethylrhodamine (solution)
|
Fluorescent Dye
|
Others
|
5(6)-TAMRA (solution) (5(6)-Carboxytetramethylrhodamine (solution)) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D2639
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .
|
-
- HY-D1435
-
|
|
Na+/K+ ATPase
Fluorescent Dye
|
Metabolic Disease
|
|
Oxonol VI is an optical indicator of membrane potential in lipid vesicles (excitation/emission wavelengths: 614/646 nm). Oxonol VI can be used to detect changes in membrane potential associated with (Na + + K +)-ATPase activity in reconstituted vesicles .
|
-
- HY-162160
-
|
|
Fluorescent Dye
|
Others
|
|
NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes .
|
-
- HY-D2230
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
|
-
- HY-162051
-
|
|
Cytochrome P450
|
Cancer
|
|
CYP1B1-IN-6 (compound 19) is a fluorescence molecular probes which inhibits CYP1B1 activity. CYP1B1-IN-6 can identify tumor sites in fluorescence imaging and photoacoustic imaging modes .
|
-
- HY-D2817A
-
-
- HY-D2510
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG2000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG2000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-W040209
-
|
α-NPO
|
Fluorescent Dye
|
Others
|
|
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .
|
-
- HY-D1434
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
|
-
- HY-D1621
-
|
|
Fluorescent Dye
|
Others
|
|
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .
|
-
- HY-135641
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
|
-
- HY-123533
-
|
NSC 12097
|
Reactive Oxygen Species (ROS)
Fluorescent Dye
|
Cancer
|
|
Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte .
|
-
- HY-D2526
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D1536
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Glycine cresol red is a complexometric indicator. Glycine cresol red forms coloured complexes with Al 3+, Ga 3+ and In 3+ ions in aqueous solutions. Glycine cresol red can been used for the spectrophotometric determination of inorganic ions. Glycine cresol red can be used as a stain in neurohistology .
|
-
- HY-D2530
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2588
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-NH2 is a polyethylene glycol derivative containing CY7.5 (HY-D0926) fluorescent dye and polyethylene glycol (PEG) and an amino group. The CY7.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy7.5 PEG-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-W154295
-
|
|
Fluorescent Dye
|
Others
|
|
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .
|
-
- HY-D2556
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D0068
-
|
7-Diethylaminocoumarin-3-carboxylic acid, SE
|
Fluorescent Dye
|
Others
|
|
DEAC, SE (7-Diethylaminocoumarin-3-carboxylic acid, SE) is an excellent blue fluorescent building block for labeling amine-containing biomolecules.
|
-
- HY-D1882
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .
|
-
- HY-W035138
-
|
|
Fluorescent Dye
MOFs
|
Others
|
|
Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins .
|
-
- HY-D2733
-
|
|
Fluorescent Dye
|
Infection
|
|
N14G is a fluorescent dye that can be used to stain bacteria such as Mycobacterium tuberculosis .
|
-
- HY-D1757
-
|
LYen; PAsp- LY
|
Fluorescent Dye
|
Others
|
|
Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
|
-
- HY-D2868
-
|
4',6-Diamidino-2-phenylindole
|
DNA Stain
Sodium Channel
|
Neurological Disease
|
|
DAPI (4',6-Diamidino-2-phenylindole) is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
|
-
- HY-DY3003
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is mainly composed of paraformaldehyde, phosphate, and deionized water, with a pH of 7.0-7.4. Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is suitable for fixing most tissues and cells, and can effectively protect the morphology and structure of tissues and cells as well as nucleic acids.
|
-
- HY-D2596
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-PEG10000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
|
-
- HY-D2217
-
-
- HY-110393
-
|
|
Fluorescent Dye
|
Cancer
|
|
CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound .
|
-
- HY-D0115
-
|
|
DNA Stain
|
Others
|
|
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .
|
-
- HY-101878R
-
|
Sulforhodamine 101 (Standard); SR101 (Standard)
|
Fluorescent Dye
Reference Standards
|
Neurological Disease
|
|
Texas Red (Standard) is the analytical standard of Texas Red (HY-101878). This product is intended for research and analytical applications. Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
|
-
- HY-D1891
-
|
|
Fluorescent Dye
|
Others
|
|
6-HEX, SE is a derivative of 6-HEX that is widely used in nucleic acid sequencing .
|
-
- HY-D1970
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 Cadaverin is a cadaverine derivative of ATTO 700 for reactions of carboxylic acids, aldehydes and ketones with maximum excitation/emission wavelengths: 700/716 nm.
|
-
- HY-D1886
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.
|
-
- HY-DY1055
-
|
|
Fluorescent Dye
|
Others
|
TSQ (solution) is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence (Ex/Em = 334/495 nm) .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2746
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
|
-
- HY-D0023
-
|
HPTS; Solvent Green 7
|
Environmental Pollutants
Fluorescent Dye
|
Others
|
|
Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu + ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .
|
-
- HY-D2348A
-
|
|
Fluorescent Dye
|
Infection
|
|
ACE TFA is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE TFA enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .
|
-
- HY-D1689
-
|
|
Bacterial
|
Infection
|
|
Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm) .
|
-
- HY-D2219
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
|
-
- HY-138147
-
|
|
Fluorescent Dye
|
Others
|
|
DCP-Rho1 is a rhodamine-labeled probe. DCP-Rho1 can be used for the detection of sulfenic acid-containing proteins. DCP-Rho1 shows λex of 560 nM, λem, 581 nm .
|
-
- HY-D1704
-
|
|
GABA Receptor
|
Neurological Disease
|
|
Bodipy TMR-X muscimol is a Bodipy labeled Muscimol (HY-N2313) (Ex=543 nm, Em=572 nm). Muscimol is a GABAA agonist. Bodipy TMR-X muscimol can be used for imaging the spread of reversible brain inactivations .
|
-
- HY-DY1059
-
|
|
Fluorescent Dye
|
Neurological Disease
|
FM1-43 (solution) is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D1423
-
|
|
Fluorescent Dye
|
Others
|
|
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .
|
-
- HY-D2601
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG3400 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG3400 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
-
- HY-DY1090
-
|
|
Fluorescent Dye
|
Others
|
BODIPY 493/503 methyl bromide (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
Solvent and concentration: DMSO: 5 mM
|
-
- HY-D2295
-
|
|
Fluorescent Dye
|
Others
|
|
Mito-FerroGreen is a mitochondria-specific ferrous ion detection probe with an excitation wavelength of 488nm .
|
-
- HY-131028
-
|
JF646 TFA
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1579
-
|
|
Fluorescent Dye
|
Others
|
|
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .
|
-
- HY-133852
-
FD-1080
1 Publications Verification
|
Fluorescent Dye
MOFs
|
Others
|
|
FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
|
-
- HY-W247103
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine 19 perchlorate is a metal free organic dye for dye sensitized solar cells.
|
-
- HY-D1416
-
HMBR
1 Publications Verification
|
Fluorescent Dye
|
Others
|
|
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .
|
-
- HY-126821A
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-3 pentaammonium is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 pentaammonium itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
|
-
- HY-D2844C
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
FITC-PEG3400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG3400-FA can be used for fluorescent labeling and imaging .
|
-
- HY-W879228
-
|
|
Fluorescent Dye
|
Others
|
|
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
|
-
- HY-D1690
-
|
|
Fluorescent Dye
|
Others
|
|
sBADA TFA is a potent green fluorescent dye. sBADA TFA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA TFA is used to label peptidoglycans in bacterial cell walls in situ. (λex=490 nm, λem=510 nm) .
|
-
- HY-D1354
-
|
|
Fluorescent Dye
|
Others
|
|
Azide MegaStokes dye 673 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-15938
-
|
|
Fluorescent Dye
|
Others
|
|
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .
|
-
- HY-151756
-
|
|
Fluorescent Dye
|
Others
|
|
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .
|
-
- HY-D2902
-
-
- HY-D2038
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 alkyne is an alkyne derivative of ATTO 550 and can be used to label proteins or antibodies.
|
-
- HY-D1045A
-
|
DABCYL sodium; Para-methyl red sodium
|
Fluorescent Dye
|
Others
|
|
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
|
-
- HY-P3362
-
|
|
Fluorescent Dye
|
Others
|
|
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
|
-
- HY-D2566
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG3400-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D1305
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 carboxylic acid is a new fluorescent label based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 carboxylic acid is a carboxylic acid derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2844E
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
FITC-PEG10000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG10000-FA can be used for fluorescent labeling and imaging .
|
-
- HY-D2487
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5 bis COOH is a derivative of Cy5 (HY-D0821) dye containing sulfonate ions. Sulfo Cy5 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2835
-
|
|
Fluorescent Dye
|
Others
|
|
mPEG-PEI-Cy5 (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 1000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2565
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG2000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2066
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 amine is an amine derivative of ATTO 680, the maximum excitation/emission wavelength: 681/698 nm.
|
-
- HY-D2557
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2488
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
|
-
- HY-D2195
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
|
-
- HY-D1975
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 Carboxy is a carboxyl derivative of ATTO 725, the maximum excitation/emission wavelength is: 728/751 nm.
|
-
- HY-D2794B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG5000-NH2 can be used for fluorescent labeling and imaging .
|
-
- HY-106594BR
-
|
Pigment blue 27 (Standard)
|
Reference Standards
Bacterial
|
Infection
Cancer
|
|
Prussian blue soluble (Standard) is the analytical standard of Prussian blue soluble (HY-106594B). This product is intended for research and analytical applications. Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
|
-
- HY-130575
-
|
|
Fluorescent Dye
|
Others
|
|
Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.
|
-
- HY-W840196
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
-
- HY-D0802
-
|
Biotin N-hydroxysuccinimide ester; NHS-Biotin
|
Fluorescent Dye
|
Others
|
|
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
|
-
- HY-D2800
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D1692
-
|
|
Fluorescent Dye
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Others
|
|
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
|
-
- HY-P1363F3
-
|
5-FAM-Amyloid β-peptide (1-42) (human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
|
-
- HY-D2433
-
|
|
Fluorescent Dye
|
Others
|
|
Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-W247131
-
DASPEI
2 Publications Verification
|
Fluorescent Dye
|
Neurological Disease
|
|
DASPEI is a cationic styrenyl mitochondrial dye with large Stokes shift. DASPEI has excitation and emission wavelength at 550/573 nm, which has good light chromogenic property. DASPEI can stain mitochondria in living cells with good labeling property. And DASPEI can also be used to stain presynaptic nerve endings independently of neuronal activity .
|
-
- HY-D2057
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 carboxy is a carboxyl derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm.
|
-
- HY-D2840E
-
|
|
Fluorescent Dye
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Others
|
|
FITC-mPEG5000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG5000 can be used for fluorescent labeling and imaging .
|
-
- HY-111956B
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-DY1056
-
|
|
Fluorescent Dye
|
Neurological Disease
|
Texas Red (Sulforhodamine 101) (solution) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D2439
-
|
|
Fluorescent Dye
|
Cancer
|
|
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
|
-
- HY-D0082
-
-
- HY-DY1028
-
|
|
Fluorescent Dye
|
Others
|
Fluo-4 AM (solution) is a cell-permeable Ca 2+ (calcium ion) indicator (Ex/Em = 485/526 nm) .
Solvent and concentration: DMSO: 1 mM
|
-
- HY-D2247
-
|
|
Fluorescent Dye
|
Others
|
|
ICG-CBT is a mixture of Indocyanine Green (ICG) and Cetyltrimethylammonium Bromide (CBT). ICG-CBT can be applied to both in vivo and in vitro to observe the structure and function of cells or tissues.
|
-
- HY-D1947
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 Streptavidin is a streptavidin derivative of ATTO 700, it can label protein or antibody, the maximum excitation/emission wavelength: 700/716 nm.
|
-
- HY-D0313
-
|
|
Fluorescent Dye
|
Others
|
|
Ethyl 8'-apo-caroten-8'-oate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W879008
-
-
- HY-D0056
-
|
|
Fluorescent Dye
|
Others
|
|
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .
|
-
- HY-149182
-
-
- HY-D1424
-
|
|
Fluorescent Dye
|
Others
|
|
Coelenterazine hcp is a Coelenterazine analogue. Coelenterazine hcp shows high sensitivity to Ca 2+. Coelenterazine hcp is suited for monitoring intracellular Ca 2+ .
|
-
- HY-137896
-
|
|
Fluorescent Dye
|
Others
|
|
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain .
|
-
- HY-W402148
-
|
|
ROS Kinase
|
Others
|
|
10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide .
|
-
- HY-D1688
-
|
|
Fluorescent Dye
|
Others
|
|
Flubida-2 is a cell permeable dye which can be hydrolyzed to Fubi-2 by endoesterases in cells (after hydrolysis, Ex=492 nm, Em=517 nm). Flubida-2 can be used to detect pH at a specific site in a cell organelle by directing the probe to where avidin fusion proteins are located .
|
-
- HY-D2749
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Bis-(N,N'-carboxylic acid)-Cy5 is a free unactivated carboxylic acid. Its absorbance and emission spectra are identical with Cy5 fluorophore.
|
-
- HY-145493
-
|
|
Fluorescent Dye
|
Others
|
|
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .
|
-
- HY-D2547
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-biotin is a polyethylene glycol derivative containing Cy5 (HY-D0821) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5-PEG5000-biotin plays an important role in the specific capture and detection of biomolecules.
|
-
- HY-151755
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-Tetrazine is a click chemistry reagent containing an tetrazine group. Sulfo-Cy3-Tetrazine is water soluble cyanine fluorescence dye, which is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.
|
-
- HY-D1952
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Amine is an amine derivative of ATTO 594, the maximum excitation/emission wavelength: 603/626 nm.
|
-
- HY-W440914C
-
|
|
Fluorescent Dye
|
Others
|
|
DSPE-PEG600-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG600-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers (Ex/Em=488/525 nm) .
|
-
- HY-D1581
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 505/515-8-C3-COOH is a green fluorescing derivative, as a fluorescent dye for imaging lipid droplets in nannochloropsis. BODIPY 505/515-8-C3-COOH can be used for the research of flow cytometric high-throughput screening and cell sorting .
|
-
- HY-D1454
-
|
|
Fluorescent Dye
|
Others
|
|
Nitro Blue Diformazan is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1747
-
-
- HY-D1632
-
|
|
Fluorescent Dye
|
Others
|
|
4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH2. 4-MU-α-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .
|
-
- HY-D1774
-
-
- HY-D0903
-
|
DFO
|
Fluorescent Dye
|
Others
|
|
1,8-Diazafluoren-9-one (DFO) is a chemical that is used to find fingerprints on porous surfaces. 1,8-Diazafluoren-9-one reacts with amino acids present in the fingerprint to form highly fluorescent derivatives (Ex/Em = ~470/570).
|
-
- HY-D2542
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2873
-
|
Sulfo Cy7(Et) tyramide
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 tyramide, a red fluorescent dye (Ex=740 nm, Em=770 nm), is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). Sulfo Cy7 tyramide can be used for multiplex Immunohistochemistry (mIHC) .
|
-
- HY-D1072
-
|
3,3′-Dipentyloxacarbocyanine iodide
|
Fluorescent Dye
|
Others
|
|
DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical .
|
-
- HY-D2132
-
|
|
Fluorescent Dye
|
Cancer
|
|
Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .
|
-
- HY-D2359
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
Glucosamine-FITC is FITC-labeled Glucosamine (HY-B1125). Glucosamine-FITC can be used to localize Glucosamine in living cells .
|
-
- HY-D2691
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 7000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-D2871
-
|
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
DAyne is a Dopamine (DA)-mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAyne is promising for research of Parkinson’s disease (PD), particularly neurotoxicity, protein modification, and related pathways (e.g., endoplasmic reticulum stress, cytoskeletal instability) caused by dopamine dysregulation .
|
-
- HY-D1985
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 Streptavidin is a streptavidin derivative of ATTO 725, it can label protein or antibody, the maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-D2692
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 10000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-175147
-
-
- HY-D2663
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 500000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
-
- HY-D2712
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-137042
-
|
Alkyne-Cy5
|
Oxidative Phosphorylation
Mitochondrial Metabolism
|
Cancer
|
|
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-DY3002
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Glutaraldehyde Fixative (4%, For Electron Microscopy) is composed of glutaraldehyde, phosphate, deionized water, etc., with a pH range of 7.2-7.4. This fixative is effective in fixing fine structures of cell nuclei and cytoplasm and is commonly used for fixing electron microscopy specimens.
|
-
- HY-D2050
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 amine is an amine derivative of ATTO 532, the maximum excitation/emission wavelength: 532/552 nm.
|
-
- HY-130735
-
|
JF646, SE; JF646, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D2221
-
-
- HY-D1339
-
|
|
Fluorescent Dye
|
|
|
Cyanine7 hydrazide dichloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-D1769
-
|
|
Fluorescent Dye
|
Others
|
|
N-hydroxy Rhodamine B amide is a ClO - indicator, which is hydrolyzed to prduce fluorescence in the presence of ClO -. The fluorescence intensity of N-hydroxy Rhodamine B amide is proportional to the product, thus can be used to quantify ClO -.
|
-
- HY-D1895
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3,5-DiBr-PAESA is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .
|
-
- HY-D2774
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Alkyne is a fluorophore. Its absorption and emission spectra are similar to fluorescein, but it is fluorescent in acidic media, and it is much more stable against photobleaching and oxidation.
|
-
- HY-D2194
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
- HY-D1508
-
-
- HY-135415
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-D2154
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D0114
-
-
- HY-101882
-
BCECF
3 Publications Verification
2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein
|
Fluorescent Dye
|
Others
|
|
BCECF is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
|
-
- HY-D1963
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 Streptavidin is a streptavidin derivative of ATTO 565, it can label protein or antibody, the maximum excitation/emission wavelength: 564/590 nm.
|
-
- HY-D1486
-
|
|
Fluorescent Dye
|
Others
|
|
4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene is a fluorescent dye for DNA sequencing .
|
-
- HY-130768
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties. N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1513
-
-
- HY-D1716
-
|
|
Fluorescent Dye
Drug Intermediate
|
Cancer
|
|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
|
-
- HY-D2415
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery .
|
-
- HY-D2814
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7 (MW 100000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 100000) can be used for fluorescent labeling and imaging .
|
-
- HY-114351
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
|
-
- HY-D2856
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
-
- HY-D2100A
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-DSPE chloride ammonium is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE chloride ammonium is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
|
-
- HY-D1343
-
|
|
Fluorescent Dye
|
|
|
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
|
-
- HY-D1981
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 Iodacetamid is an iodoacetamide derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.
|
-
- HY-D1350
-
|
|
Fluorescent Dye
|
|
|
5-ROX-alkyne is a rhodamine dye that labels DNA fragments. It enables visualization of the results of capillary electrophoresis genotyping experiments and gel shift experiments.
|
-
- HY-D2708
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-107864
-
|
Tetraiodofluorescein
|
Fluorescent Dye
|
Infection
|
|
Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .
|
-
- HY-D2142
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-D1958
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 564/590 nm.
|
-
- HY-151753
-
|
|
Fluorescent Dye
|
Others
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
|
-
- HY-D1706
-
|
|
DNA Stain
|
Others
|
|
AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA .
|
-
- HY-59021
-
|
|
Fluorescent Dye
|
Others
|
|
2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole is a laser dyes with high photoluminescence (PL) quantum efficiency .
|
-
- HY-D2794A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG1000-NH2 can be used for fluorescent labeling and imaging .
|
-
- HY-D2001A
-
|
|
Fluorescent Dye
|
Others
|
|
TTO 488 NHS ester TEA is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. TTO 488 NHS ester TEA is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-110257
-
|
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Fluorescent Dye
|
Others
|
|
BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λabs: 504 nm; λem:510 nm .
|
-
- HY-D0161
-
|
|
Fluorescent Dye
|
Others
|
|
ZnAF-2F DA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D0211
-
|
|
Fluorescent Dye
|
Cancer
|
|
Phenolphthalein is an acid-base indicator that is colorless in an acidic environment and pink in an alkaline environment. Phenolphthalein is genotoxic and potentially carcinogenic to mice. In addition, phenolphthalein is also a blood indicator .
|
-
- HY-D2387
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo CY3.5 hydrazide is sulfonated Cy3.5 with good water solubility. λex=591 nm, λem=604 nm.
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-
- HY-111956A
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-D1767
-
-
- HY-D1957
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D2665
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
-
- HY-D2277
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein-CM2 is a fluorogenic molecule that can be used to rapidly screen esterase cut sites for protein-protein interaction-dependent (PPI-dependent) esterase activity in E. coli .
|
-
- HY-D1523
-
|
|
Cathepsin
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Others
|
|
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm) .
|
-
- HY-D2840
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-mPEG350 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG350 can be used for fluorescent labeling and imaging .
|
-
- HY-D0283
-
-
- HY-D2858A
-
|
|
Fluorescent Dye
|
Others
|
|
8-arm-PEG20000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
-
- HY-D0095
-
|
|
Fluorescent Dye
|
Others
|
|
B261 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2019
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-D2597
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-PEG2000-biotin is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5-PEG2000-biotin is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em=770/820 nm).
|
-
- HY-D1867
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D2228
-
|
|
Fluorescent Dye
|
Cancer
|
|
IR-7 is a mitochondria-targeted heptamethylindocyanine dye, and can used for cancer study.
|
-
- HY-135414A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
-
- HY-103466
-
|
|
Fluorescent Dye
|
Others
|
|
FM4-64 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers.
|
-
- HY-W330621
-
|
CNP-α-D-Glucopyaoside
|
Fluorescent Dye
|
Others
|
|
2-Chloro-4-nitrophenyl-α-D-glucopyranoside (CNP-α-D-Glucopyaoside) as a chromogenic substrate for the enzymatic activity assay of the enzyme that releases CNP from conjugated carbohydrates .
|
-
- HY-D1744
-
|
|
Fluorescent Dye
|
Others
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
- HY-125746
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
|
-
- HY-D2134
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-139579
-
|
OTL 38
|
Fluorescent Dye
|
Cancer
|
|
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
|
-
- HY-D0922A
-
-
- HY-D2800B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG3400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D1310
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-D2826E
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Chitosan (MW 2000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 2000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2796C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG10000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG10000-OH can be used for fluorescent labeling and imaging .
|
-
- HY-D1948
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-D0121A
-
|
|
Fluorescent Dye
|
Others
|
|
INDO 1 pentapotassium is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
|
-
- HY-D2529
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D0789
-
|
|
Fluorescent Dye
|
Others
|
|
ANTS is a fluorescent dye (Excitation wavelength: 380 nm; Emission wavelength: 520 nm). ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage .
|
-
- HY-D0082R
-
|
|
Fluorescent Dye
Reference Standards
|
Others
|
|
7-Diethylamino-4-methylcoumarin (Standard) is the analytical standard of 7-Diethylamino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Diethylamino-4-methylcoumarin is a laser dye .
|
-
- HY-101900
-
|
Nile blue sulfate
|
Fluorescent Dye
|
Others
|
|
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
-
- HY-D2609
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG1000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG1000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
-
- HY-D2848C
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy5.5 (MW 100000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 100000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
-
- HY-D2242
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
-
- HY-173418
-
|
cPGI-biotin; Carbacyclin-biotin
|
Prostaglandin Receptor
|
Cardiovascular Disease
Endocrinology
|
|
Carbaprostacyclin-biotin (cPGI-biotin; Carbacyclin-biotin) is a biotin-bound Carbacyclin (Carbaprostacyclin) (HY-112322). Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation .
|
-
- HY-D2848B
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy5.5 (MW 1000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 1000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
-
- HY-DY3001
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Glutaraldehyde Fixative (2.5%, For Electron Microscopy) is composed of glutaraldehyde, phosphate, deionized water, etc., with a pH range of 7.2-7.4. This fixative is effective in fixing fine structures of cell nuclei and cytoplasm and is commonly used for fixing electron microscopy specimens.
|
-
- HY-D2772
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-D2098
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG2-NH2 is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
|
-
- HY-D1502
-
-
- HY-DY1067
-
|
|
Fluorescent Dye
DNA Stain
|
Others
|
Cy5 maleimide (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-101880
-
ADHP
2 Publications Verification
10-Acetyl-3,7-dihydroxyphenoxazine
|
Fluorescent Dye
|
Others
|
|
ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
|
-
- HY-W998687
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 dimethyl is a free non-activated dye. This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration.
|
-
- HY-D2796A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG1000-OH can be used for fluorescent labeling and imaging .
|
-
- HY-D0722
-
|
5-(6)-Carboxyfluorescein diacetate; CFDA
|
Fluorescent Dye
|
Others
|
|
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D1080
-
EDANS
3 Publications Verification
1,5-EDANS
|
Fluorescent Dye
|
Others
|
|
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) .
|
-
- HY-135367
-
|
Pyridyl CTZ
|
Fluorescent Dye
|
Others
|
|
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .
|
-
- HY-D2071
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 681/698 nm.
|
-
- HY-DY1070
-
|
|
Fluorescent Dye
|
Others
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D2437
-
|
|
Fluorescent Dye
Antibiotic
|
Cardiovascular Disease
Cancer
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
-
- HY-D1862
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2170
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 streptavidin is a fluorescently labeled streptavidin. AF488 streptavidin is a streptavidin conjugated to Alexa Fluor 488, with 4 fluorophores per protein molecule, enabling stoichiometric fluorescent labeling of cell surface targets. AF488 streptavidin can form a complex with biotinylated E07 aptamer to stain cells expressing EGFR, and the staining is reversible after treatment with mA9 detoxifying oligonucleotides (Ex/Em = 470/520 nm) .
|
-
- HY-D2064
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 streptavidin is a streptavidin derivative of ATTO 680, it can label protein or antibody, the maximum excitation/emission wavelength: 681/698 nm.
|
-
- HY-D1921
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 iodoacetamide is the iodoacetamide derivative of ATTO 390, the maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D2677
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 100000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-D1497
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent Red Mega 480 is a dye that is specifically designed for multicolor techniques. Fluorescent Red Mega 480 is characterized by an extremely large stoke′s shift between excitation and emission maxima .
|
-
- HY-D2181
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
-
- HY-137928
-
|
|
Fluorescent Dye
|
Others
|
|
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .
|
-
- HY-W142395
-
|
|
DNA Stain
|
Others
|
|
6-TAMRA free acid is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry.
|
-
- HY-D2188
-
|
|
Deubiquitinase
|
Cancer
|
|
IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .
|
-
- HY-D2825
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7.5 (MW 100000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 100000) can be used for fluorescent labeling and imaging .
|
-
- HY-D1358
-
|
|
Fluorescent Dye
|
Others
|
|
Alkyne MegaStokes dye 608 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2056
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 700/716 nm.
|
-
- HY-DY1011
-
|
|
Fluorescent Dye
|
Others
|
PKH 26 (solution) is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm) , which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies .
Solvent and concentration: DMSO: 5 mM
|
-
- HY-101893
-
|
|
Fluorescent Dye
|
Others
|
|
Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
|
-
- HY-D2675
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 10000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-153524
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-W127705
-
|
|
Fluorescent Dye
|
Others
|
|
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
|
-
- HY-D2229
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5 amine is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-W591393
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Biotin Azide Plus is an oxazolidine reagent that integrates azide-biotin click chemistry and a photocleavable linker arm. Biotin Azide Plus not only reacts with biotin thioether to form stable sulfinimide products, but also enables bioconjugation of proteins and DNA through biotin redox-activated chemical labeling technology. Taking advantage of the streptavidin capture and photo-release properties, Biotin Azide Plus effectively facilitates the isolation of lipid-derived electrophile-protein adducts, thus finding wide application in scientific research related to fields such as SKBR3 cancer .
|
-
- HY-W073524
-
|
|
Fluorescent Dye
|
Others
|
|
DFAME is a red fluorophore (Ex = 508 nm, Em = 641 nm). DFAME binds to Beetroot and Corn (dimeric fluorescent RNA aptamers) to form Beetroot-DFAME (Kd = 460 nM) and Corn-DFAME (Kd = 3600 nM). Beetroot-DFAME and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research .
|
-
- HY-D2166
-
|
|
Fluorescent Dye
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Others
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|
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
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-
- HY-D1760
-
|
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Fluorescent Dye
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Others
|
|
SBFI is a cell-impermeant, fluorescent Na + indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm . SBFI selective for Na + over K + with Kd values of 20 and 120 mM for these ions, respectively. .
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-
- HY-D3064
-
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Biochemical Assay Reagents
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Others
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|
510 Calibration probe is a chemiluminescent group that can be used as a probe for in vivo imaging studies, with an emission maximum around 520 nm .
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-
- HY-D2355
-
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Biochemical Assay Reagents
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Others
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|
Tris-NTA Biotin is a biotin-labeled version of tris-NTA. Tris-NTA Biotin, as a bridge connecting His-tagged proteins with streptavidin, can reversibly label proteins and cell surfaces. Tris-NTA Biotin can be used in experiments such as protein immobilization, kinetic determination, live cell labeling, and Western blot detection .
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-
- HY-D1043
-
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Fluorescent Dye
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Others
|
|
1,4-Dichloro 6-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
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-
- HY-156305
-
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|
Fluorescent Dye
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Others
|
|
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.
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-
- HY-D2534
-
|
|
Fluorescent Dye
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Others
|
|
Cy5-PEG3400-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-129109
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H2O2, ClO -, O2 -?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .
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-
- HY-D0214A
-
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Fluorescent Dye
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Others
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|
Acid Red 94 lactone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D1984
-
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Fluorescent Dye
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Others
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|
ATTO 633 Alkin is an alkyne derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.
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-
- HY-D0720
-
|
NSC-151912; L-6868
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
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Others
|
|
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
|
-
- HY-124324
-
|
p-Nitopheyl β-D-cellotioside
|
Fluorescent Dye
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Others
|
|
4-Nitrophenyl β-D-cellotrioside (p-Nitopheyl β-D-cellotioside) is a chromogenic substrate for endoglucanases and cellulose biohydrolases. As a fluorescent dye, nitrophenyl β-D-Cellotrioside can be hydrolyzed by enzymes to release 4-nitrophenol, producing a yellow color. The activity of the enzyme can be quantitatively analyzed by monitoring the change in absorbance at 405 nm .
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-
- HY-D1754
-
|
LYCH ammonium
|
Fluorescent Dye
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Others
|
|
Lucifer yellow CH (LYC) ammonium is a thiol-reactive fluorescent polar tracer.
|
-
- HY-D2857
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
NBD-Stearic acid is a stearic acid labeled with a nitrobenzoxadiazole (NBD) fluorophore. NBD-Stearic acid can be used as a probe for fatty acid uptake or the the ligand binding sites of fatty acid and sterol carrier proteins (FABP)
|
-
- HY-D1668
-
|
|
DNA Stain
Reverse Transcriptase
|
Infection
Neurological Disease
Cancer
|
|
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
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-
- HY-D2320
-
|
|
Fluorescent Dye
|
Others
|
|
ER Flipper-TR 28 is a flipper probe with a small molecule fluorophore that can image membrane tension in the endoplasmic reticulum (ER). ER Flipper-TR 28 bears a pentafluorophenyl group and also reacts with protein thiolate on the ER surface facing the cytoplasm .
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-
- HY-D1436
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
PBFI is the cell-impermeant fluorescent indicator that is widely used for the determination of concentrations of K + (Ex/Em = 340,380/500 nm) .
|
-
- HY-D1048
-
|
Cy7 DiC18
|
Fluorescent Dye
|
Cancer
|
|
DiR is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
-
- HY-32264
-
|
X-NeuNAc
|
Bacterial
|
Others
|
|
X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase.
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-
- HY-118540
-
|
Diazoresorcinol
|
Fluorescent Dye
Bacterial
|
Infection
|
|
Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
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-
- HY-D2044
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 532 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 532/552 nm.
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-
- HY-DY1063
-
|
|
Fluorescent Dye
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Others
|
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM
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-
- HY-D2826C
-
|
|
Fluorescent Dye
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Others
|
|
FITC-Chitosan (MW 10000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 10000) can be used for fluorescent labeling and imaging .
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-
- HY-D1713
-
|
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Reactive Oxygen Species (ROS)
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Others
|
|
CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive .
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-
- HY-D1993
-
|
|
Fluorescent Dye
HIV
|
Infection
|
|
ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .
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-
- HY-D1749
-
|
|
Fluorescent Dye
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Others
|
|
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.
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-
- HY-D1357
-
|
|
Fluorescent Dye
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Others
|
|
Alkyne MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2095
-
|
|
Fluorescent Dye
|
Cancer
|
|
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .
|
-
- HY-110251
-
|
|
DNA Stain
|
Others
|
|
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
|
-
- HY-D1051
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid. Cy3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 548/563 nm).
|
-
- HY-D2481
-
|
APG-2 (TMA)
|
Fluorescent Dye
|
Neurological Disease
|
|
Asante potassium green-2 (APG-2) TMA is a cell-impermeable K + (potassium ion) fluorescent indicator that produces a fluorescent response to changes in extracellular potassium ion concentration. Its excitation/emission maxima are 525/545 nm , respectively.
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-
- HY-D1116
-
|
|
Fluorescent Dye
|
Others
|
|
MitoMark Red I is a fluorescent mitochondrial marker. MitoMark Red I is a red fluorescent dye which accumulates in mitochondria in viable cells and has an excitation wavelength of 578 nm and emission of 599 nm .
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-
- HY-D1488
-
|
|
Fluorescent Dye
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Others
|
|
Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate (Compound 3) is a Mg 2+ selective fluorescent indicator .
|
-
![Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate](//file.medchemexpress.com/product_pic/hy-d1488.gif)
- HY-D1881
-
-
- HY-W011422
-
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NSC 528
|
Fluorescent Dye
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Others
|
|
2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone (NSC 528) is a colorimetric dye used for the detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone reacts with phenolic compounds at a pH of about 9.4 to produce an indigo dye. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has also been used in a colorimetric reaction for the quantitative colorimetric detection of aflatoxins, turning the colorless aflatoxins green with an absorption band at 673 nm.
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-
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dye
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Others
|
|
Janelia Fluor 525, SE (JF525, SE) (the SE form of compound 12) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor 525, SE contains an NHS ester, which can be used to label primary amines and is suitable for live cell imaging.
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-
- HY-D2012
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
|
-
- HY-D2645
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 100000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-D2441
-
|
|
Fluorescent Dye
|
Cancer
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
-
- HY-D3393
-
|
|
Fluorescent Dye
Epigenetic Reader Domain
|
Cancer
|
|
JQ1-FITC TFA is a BRD4-binding fluorescent tracer. JQ1-FITC TFA binds to BRD4 BD1, BD2, recombinant bromodomains, and endogenous BRD4 in cell lysates. JQ1-FITC TFA can be used for the research of breast cancer and cancer (Ex/Em = 495/525 nm) .
|
-
- HY-D1941
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 Streptavidin is a streptavidin derivative of ATTO 590, it can label protein or antibody, the maximum excitation/emission wavelength: 594/622 nm.
|
-
- HY-D2559
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-DY1066
-
|
|
Fluorescent Dye
|
Others
|
Cy3 (Sulfo-Cyanine3) (solution) is an orange-fluorescent label for protein and nucleic acid (λex=554, λem=568).
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2141
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W414549
-
-
- HY-D1401
-
|
|
Fluorescent Dye
|
Others
|
|
OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences .
|
-
- HY-D1929
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
- HY-P1169
-
|
|
Caspase
|
Others
|
|
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
|
-
- HY-DY1050
-
|
|
DNA Stain
|
Others
|
Ethidium bromide (solution) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
Solvent and Concentration: Sterile water: 10 mg/Ml
|
-
- HY-D1701
-
|
|
Fluorescent Dye
|
Others
|
|
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.
MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
|
-
- HY-131024
-
|
JF549, Tetrazine
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D2540
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG10000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2802A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG1000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-101879
-
|
|
DNA Stain
Parasite
Fluorescent Dye
|
Others
|
|
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
|
-
- HY-DY1052
-
|
|
Fluorescent Dye
|
Others
|
Monochlorobimane (Chlorobimane) (solution) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D1587
-
|
|
Fluorescent Dye
|
Others
|
|
8-Phenyl-2,6-diethyl-BODIPY 505/515 is a derivative of BODIPY 505/515 (Ex=525 nm，Em=544 nm) .
|
-
- HY-D2307
-
-
- HY-D1546
-
|
|
Fluorescent Dye
|
Cancer
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-D2693
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 50000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-DY1084
-
|
|
Fluorescent Dye
|
Others
|
DiD perchlorate (solution)is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
Solvent and concentration: DMSO: 5 mM
|
-
- HY-D2632
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
-
- HY-D2744
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 TCO reacts with tetrazines to produce a stable, covalent linkage, also referred to as the inverse-electron demand Diels-Alder cycloaddition reaction. This reaction is extremely fast (k > 800 M-1 s-1), selective, biocompatible, and does not require Cu-catalyst or elevated temperatures. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
|
-
- HY-D2845B
-
|
|
Fluorescent Dye
|
Others
|
|
4-Arm-PEG10000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG10000-FITC can be used for fluorescent labeling and imaging .
|
-
- HY-D0022
-
|
5-AF
|
Fluorescent Dye
|
Others
|
|
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .
|
-
- HY-101902
-
|
Quin-2 acetoxymethyl ester
|
Fluorescent Dye
|
Others
|
|
Quin-2AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Quin-2AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
-
- HY-W923198
-
|
Methacryloyloxy fluorescein
|
Fluorescent Dye
|
Others
|
|
Fluorescein O-methacrylate (Methacryloyloxy fluorescein) is a pH-responsive fluorescent monomeric dye. Fluorescein O-methacrylate exhibits pH-responsive fluorescence properties: its fluorescence is activated under alkaline conditions and quenched under neutral or acidic conditions; reversible switching of fluorescence is achievable by adjusting the pH of the solution. Fluorescein O-methacrylate can be used as a monomer for the synthesis of amphiphilic fluorescein polymers. These polymers can self-assemble into stable polymer nanoparticles with enhanced aqueous-phase fluorescence, and also enable the conjugation of nanoparticles with amine-containing biomolecules to support sensitive optical detection of biomarkers (Ex/Em = 490/520 nm) .
|
-
- HY-W248115
-
|
|
Fluorescent Dye
|
Others
|
|
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .
|
-
- HY-101896
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-4 AM is a cell-permeable Ca 2+ (calcium ion) indicator (Ex/Em = 485/526 nm) .
|
-
- HY-D0924B
-
|
Sulfo-Cyanine5.5 TEA
|
Fluorescent Dye
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Cy5.5 TEA is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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-
- HY-D1951
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Biotin is a biotin derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-D2598
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-PEG5000-biotin is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5-PEG5000-biotin is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em=770/820 nm).
|
-
- HY-D1768
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-4FF AM is a cell-permeant fluorescent calcium indicator. Fluo-4FF is an analog of Fluo-4 with a lower affinity for calcium, which is suitable for investigation of relatively high level of intracellular calcium.
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-
- HY-D2688
-
|
|
Fluorescent Dye
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Others
|
|
Cy7 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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-
- HY-D2671
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
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-
- HY-D2705
-
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Fluorescent Dye
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Others
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|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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-
- HY-D1899
-
|
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Fluorescent Dye
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Others
|
|
VIC phosphoramidite, 6-isomer is a VIC derivative that can be used for conjugating VIC to other molecules. VIC can be used for labeling oligonucleotides at the 5’-end .
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-
- HY-D2499
-
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|
Fluorescent Dye
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Others
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|
Sulfo Cy7 DBCO potassium is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. Sulfo Cy7 DBCO potassium is a click chemistry reagent. Sulfo Cy7 DBCO potassium contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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-
- HY-131022
-
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JF549 TFA
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Fluorescent Dye
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Others
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|
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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-
- HY-D2796B
-
|
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Fluorescent Dye
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Others
|
|
FITC-PEG5000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG5000-OH can be used for fluorescent labeling and imaging .
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-
- HY-D2519
-
|
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Fluorescent Dye
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Others
|
|
Cy3-PEG2000-biotin is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy3-PEG2000-biotin plays an important role in the specific capture and detection of biomolecules .
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-
- HY-D0819A
-
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Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
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Fluorescent Dye
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Others
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|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
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-
- HY-D1611
-
|
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Fluorescent Dye
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Others
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
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-
- HY-135056
-
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|
Fluorescent Dye
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Others
|
|
Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.
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-
- HY-D2604
-
|
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Fluorescent Dye
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Others
|
|
ICG PEG1000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG1000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
-
- HY-DY1061
-
|
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Fluorescent Dye
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Others
|
BODIPY 558/568 C12 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
Solvent and concentration: DMSO: 2 mM
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-
- HY-D0006A
-
|
|
Fluorescent Dye
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Others
|
|
Bathophenanthroline disulfonic acid sodium is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-15935C
-
|
|
β-glucuronidase
Fluorescent Dye
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Others
|
|
X-Gluc sodium is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue) .
|
-
- HY-D0824
-
|
Sulfo-Cyanine7 Succinimidyl Ester
|
Fluorescent Dye
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Others
|
|
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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-
- HY-D2801B
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG3400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG3400-NHS can be used for fluorescent labeling and imaging .
|
-
- HY-D1529
-
|
|
Fluorescent Dye
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Others
|
|
4-Methylumbelliferyl phosphate (2-amino-2-methyl-1,3-propanediol) is a fluorescent substrate, can be used as substrate buffer of enzyme assay .
|
-
- HY-D2196
-
|
|
Fluorescent Dye
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Others
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
|
-
- HY-104057
-
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|
Fluorescent Dye
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Others
|
|
Rhod-FF AM is a fluorescent calcium indicator. Rhod-FF AM is cell permeable and is hydrolyzed by intracellular esterases to generate Rhod-FF .
|
-
- HY-D1235
-
|
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Fluorescent Dye
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Others
|
|
Fluorescent brightener 210 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2612
-
|
|
Fluorescent Dye
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Others
|
|
ICG PEG5000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG5000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
-
- HY-D3389
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .
|
-
- HY-D0051
-
|
|
Fluorescent Dye
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Others
|
|
5(6)-Carboxy-eosin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1418
-
|
|
Fluorescent Dye
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Others
|
|
CP-BP-SFAC is a luminogenic molecule. CP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films .
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-
- HY-D2854C
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG3400-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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-
- HY-D2842
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG400-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG400-biotin can be used for fluorescent labeling and imaging .
|
-
- HY-D0112
-
|
|
Fluorescent Dye
|
Others
|
|
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm) .
|
-
- HY-101892
-
|
|
Fluorescent Dye
|
Others
|
|
DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential.
|
-
- HY-D0893
-
|
|
Fluorescent Dye
|
Others
|
|
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
|
-
- HY-D2055
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 532 cadaverin is a cadaverine derivative of ATTO 532, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 532/552 nm.
|
-
- HY-D0010
-
|
Dibromopyrogallolsulfonphthaleine
|
Fluorescent Dye
|
Others
|
|
Bromopyrogallol red (Dibromopyrogallolsulfonphthaleine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1748
-
|
|
Fluorescent Dye
|
Others
|
|
Rhodamine B hexyl ester perchlorate is a cell-permeant, orange-fluorescent dye for mitochondria.
|
-
- HY-D2796
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG400-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG400-OH can be used for fluorescent labeling and imaging .
|
-
- HY-D1261
-
|
Thiol-green 1
|
Fluorescent Dye
|
Others
|
|
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells . Ex: 488 nM; Em: 540 nM.
|
-
- HY-D2678
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 500000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-D1990
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 Azide is an azide derivative of ATTO 520 with excitation/emission maxima at 620/642 nm.
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-
- HY-D2171A
-
|
|
Fluorescent Dye
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Others
|
|
AF488 DBCO ditriethylamineis a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO ditriethylaminemediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
-
- HY-D2152
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
-
- HY-D2240
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5-DBCO is a fluorescent dye. Sulfo-Cy3.5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D1999
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
- HY-D2068
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 iodacetamid is an iodoacetamide derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
-
- HY-118159
-
|
DPPP
|
Fluorescent Dye
|
Others
|
|
Diphenyl-1-pyrenylphosphine (DPPP) is a functional organic molecule with both fluorescent properties and metal coordination ability, which is commonly used in materials and coordination chemistry research. Upon exposure to ultraviolet light, Diphenyl-1-pyrenylphosphine undergoes photoinduced phosphorus atom oxidation to form O-DPPP, triggering a transition from aggregation-induced emission (AIE) to aggregation-caused quenching (ACQ). Diphenyl-1-pyrenylphosphine reacts stoichiometrically with lipid hydroperoxides to produce fluorescent diphenyl-1-pyrenylphosphine oxide. Diphenyl-1-pyrenylphosphine can insert into cell membranes to monitor lipid peroxidation processes in living cells .
|
-
- HY-D0026
-
|
7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .
|
-
- HY-D2175
-
|
|
Fluorescent Dye
|
Others
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 552/566 nm) .
|
-
- HY-D2192
-
-
- HY-D2633
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
-
- HY-D1868
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 azide plus is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with an azide functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The azide group of Cy3 azide plus can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-156309
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-172268
-
|
|
Fluorescent Dye
|
Others
|
|
R6G phosphoramidite for oligonucleotide synthesis, pure 6-isomer. R6G (rhodamine 6G) is a xanthene dye of the rhodamine family with high fluorescence quantum yield and high molar extinction coefficient. Relative to those of fluorescein, the absorption (518 nm) and emission (542 nm) maxima of 6-R6G are shifted into the long-wave region.
|
-
- HY-D2024
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 streptavidin is a streptavidin derivative of ATTO 550, it can label protein or antibody, the maximum excitation/emission wavelength: 554/576 nm.
|
-
- HY-W008292
-
|
|
Fluorescent Dye
|
Others
|
|
Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion .
|
-
- HY-D0083
-
|
DiIC18(3)
|
Fluorescent Dye
|
Others
|
|
DiI is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
-
- HY-D2626
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA (MW 100000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
-
- HY-DY2002
-
|
|
Fluorescent Dye
Glycosidase
|
Others
|
X-GAL (BCIG) (solution) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
Solvent and Concentration: DMF: 20 mg/mL
|
-
- HY-D1932
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
- HY-D0100
-
|
|
Fluorescent Dye
|
|
|
Fluorescein-diacetate-5-isothiocyanat is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D2101
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
|
-
- HY-D2610
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG2000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG2000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
-
- HY-W998680
-
|
5-FITC-Maleimide
|
Fluorescent Dye
|
Others
|
|
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
|
-
- HY-D148410F
-
|
Cy5-STK-001 negative control
|
Fluorescent Dye
|
Neurological Disease
|
|
Cy5-Zorevunensen negative control (Cy5-STK-001 negative control) is an antisense oligonucleotide labeled with the fluorescent molecule Cy5, which can be used as a negative control for Zorevunersen (HY-148410) .
|
-
- HY-132270
-
|
|
Fluorescent Dye
|
Others
|
|
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
|
-
- HY-D2672
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-D2741
-
|
|
Fluorescent Dye
|
Others
|
|
MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1734
-
|
|
LXR
|
Cardiovascular Disease
|
|
FITC-GW3965 is a fluorescence-labelled liver X receptor β (LXRβ) agonist GW3965 (HY-10627). FITC-GW3965 is a tracer, that can be designed by replacing the trifluoromethyl of GW3965 with an amide to link the FITC. FITC-GW3965 can be used to study the function of LXRβ .
|
-
- HY-D1385
-
|
|
Fluorescent Dye
|
Others
|
|
JF526–Pepstatin A TFA is a fluorescent dye that can be used for lysosomal staining in live cells. The excitation maximum is 530 nm and the emission maximum is 549 nm .
|
-
- HY-D2872
-
|
|
Fluorescent Dye
|
Others
|
|
5-AF594 tyramide is a red fluorescent dye (Ex=590 nm, Em=618 nm). 5-AF594 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-AF594 tyramide can be used for multiplex immunohistochemistry (mIHC) .
|
-
- HY-D2073
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
- HY-DY1038
-
|
|
Fluorescent Dye
|
Others
|
Acridine Orange hydrochloride (solution) is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
Solvent and Concentration: Sterile water: 10 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D1251
-
|
|
Fluorescent Dye
|
Others
|
|
TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells .
|
-
- HY-D2836E
-
|
FITC-Hyaluronate (MW 10000)
|
Fluorescent Dye
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Others
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FITC-HA (MW 10000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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-
- HY-D2594
-
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Fluorescent Dye
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Others
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Cy7.5-PEG3400-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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-
- HY-D2533
-
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Fluorescent Dye
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Others
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Cy5-PEG2000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1447
-
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Fluorescent Dye
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Others
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Fluo-3FF pentapotassium is a cell-impermeant fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
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-
- HY-W440914A
-
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Fluorescent Dye
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Others
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DSPE-PEG400-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG400-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .
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- HY-D1979
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Fluorescent Dye
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Others
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ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
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- HY-D2628
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Fluorescent Dye
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Others
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Cy3 HA (MW 500000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-D2851B
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Fluorescent Dye
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Others
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FITC-PEG5000-CHOL is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG5000-CHOL is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em=488/525 nm) .
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- HY-D1850
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D2079
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Fluorescent Dye
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Others
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ATTO 665 azide is an azide derivative of ATTO 665 with excitation/emission maxima at 663/680 nm.
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- HY-D2161A
-
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Fluorescent Dye
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Others
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AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne) .
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-
- HY-D1268
-
|
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Fluorescent Dye
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Cancer
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|
Seph-PAO is the modified PAO attached a sepharose fluorophore and is used to detect the thioredoxin reductase (TrxR) .
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-
- HY-D2627
-
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Fluorescent Dye
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Others
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Cy3 HA (MW 200000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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-
- HY-D0969
-
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DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate
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Fluorescent Dye
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Others
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DiO is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
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-
- HY-D2647
-
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Fluorescent Dye
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Others
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Cy5 HA (MW 500000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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-
- HY-D2324
-
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Fluorescent Dye
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Others
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EE-Flipper 33 is a Flipper probe designed to evaluate the mechanism of early endocytosis. EE-Flipper has a pKa value of 10.6 and is capable of tracking approximately 70% of early endosomes (EE) in live cells. Furthermore, EE-Flipper 33 can also label the Golgi apparatus in live cells with an internal pH ranging from 6.0 to 6.7 .
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-
- HY-D1515
-
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Neurodye GH1-84
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Fluorescent Dye
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Neurological Disease
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|
FM1-84 (Neurodye GH1-84) is a fluorescent dye. FM1-84 has lipophilic and facilitates association with membranes, resulting in an increase in fluorescence intensity (λex=510 nm, λem=625 nm). FM1-84 can be used for synaptic vesicle recycling in neurons research .
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-
- HY-P1005
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-
- HY-101974
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Biochemical Assay Reagents
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Others
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Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.
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-
- HY-N0729F
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Fluorescent Dye
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Metabolic Disease
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|
BODIPY-Linoleic acid is a conjugate of the BODIPY fluorophore and Linoleic acid (HY-N0729) (C18:2) and is a lipid metabolism probe.
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-
- HY-138658
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JF526, SE; JF526, NHS
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Fluorescent Dye
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Others
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Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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-
- HY-D0078
-
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Fluorescent Dye
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Others
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|
DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein .
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-
- HY-151662
-
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N3-TFBA
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ADC Linker
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Others
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4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1853A
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Fluorescent Dye
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Others
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Sulfo-Cy5 carboxylic acid TEA is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
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-
- HY-D1753
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LYC
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Fluorescent Dye
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Others
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|
Lucifer yellow cadaverine (LYC) can be used as a cell tracer. Lucifer yellow cadaverine can be used to label endocytic vacuoles in cells .
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-
- HY-D2018
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Fluorescent Dye
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Others
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|
ATTO 550 carboxy is a carboxyl derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
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-
- HY-DY1037
-
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Fluorescent Dye
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Others
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Dihydrorhodamine 123 (DHR 123) (solution) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
Solvent and concentration: DMSO: 10 mM
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-
- HY-151615
-
|
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Fluorescent Dye
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Neurological Disease
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|
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB) .
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-
- HY-D1109
-
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Fluorescent Dye
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Others
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5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins .
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-
- HY-121608
-
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Lumiflavine
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Fluorescent Dye
Notch
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Cancer
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|
Lumiflavin (Lumiflavine), a riboflavine analog, causes significant inhibition of riboflavine uptake. Lumiflavin can effectively reduce the riboflavin enrichment in cancer stem-like cells (CSCs) and sensitize the effect of cisplatin Diamminedichloroplatinum (DDP) on CSCs. Lumiflavin is promising for research of ovarian cancer .
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-
- HY-D125859F
-
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HRP-Biotin
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Biochemical Assay Reagents
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Others
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Peroxidase, Horseradish, Biotin labeled (HRP-Biotin) can be used to encapsulate DNA nanoflowers for creating stabilized streamlined ELISA platforms resistant to harsh environment .
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-
- HY-D2770
-
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Fluorescent Dye
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Others
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Cyanine3.5 dimethyl is a non-sulfonated cyanine dye with good solubility in organic solvents and bright fluorescence in the yellow-orange spectrum range. The dye can be used as a non-reactive fluorophore for control experiments, calibration, and other technical applications.
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-
- HY-D1390A
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Fluorescent Dye
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Others
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Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
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-
- HY-D2698
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Fluorescent Dye
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Others
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Cy7.5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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-
- HY-D0952
-
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Parasite
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Others
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Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .
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-
- HY-D2701
-
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Fluorescent Dye
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Others
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|
Cy7.5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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-
- HY-15923
-
|
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Reactive Oxygen Species (ROS)
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Others
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MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
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-
- HY-D2523
-
|
|
Folate Receptor (FR)
Fluorescent Dye
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|
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Cy3-PEG2000-FA is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG2000-FA can be readily traced by its intense red fluorescent signal. Cy3-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection.
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-
- HY-D1249
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Fluorescent Dye
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Others
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Calcein (mixture of isomers), Calcein (HY-D0040) Derivative, is a fluorescent dye (Ex/Em = 495/515 nm). Calcein (mixture of isomers) can be used for the researches for live cell staining, calcium ion detection, bone fluorescence labeling and membrane permeability leakage detection.
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-
- HY-D2683
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Fluorescent Dye
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Others
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|
Cy7 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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-
- HY-D2799
-
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Fluorescent Dye
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Others
|
|
Chitosan-Cy7 (MW 7000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 7000) can be used for fluorescent labeling and imaging .
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-
- HY-D1593
-
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Fluorescent Dye
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Others
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|
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.
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-
- HY-D2147
-
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Fluorescent Dye
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Others
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Cy5-PEG7-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-D0141
-
-
- HY-D0069
-
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|
Fluorescent Dye
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Others
Cancer
|
|
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
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- HY-149117
-
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Fluorescent Dye
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Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
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-
- HY-W039519
-
|
|
Fluorescent Dye
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Cancer
|
|
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
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-
- HY-D2851
-
|
|
Fluorescent Dye
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Others
|
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FITC-PEG2000-CHOL is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG2000-CHOL is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em=488/525 nm) .
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-
- HY-D1852
-
|
|
Fluorescent Dye
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Others
|
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1189
-
|
Lucifer Yellow 3-amino-D-alanine
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Fluorescent Dye
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Others
|
|
YADA (Lucifer Yellow 3-amino-D-alanine) is a conjugate of the fluorescent dyes Lucifer yellow and D-alanine, which is a green-yellow fluorescent dye. YADA is suitable for labeling peptidoglycans in living bacteria that can be incorporated into the cell wall where they are being synthesized. YADA has a large Stokes shift and a wide emission spectrum, allowing excitation through a purple light source and detection using a green filter. YADA showed good water solubility, light stability and thermal stability.
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-
- HY-D1848
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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-
- HY-D2037
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 550 hydrazid is a hydrazide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
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-
- HY-D1068
-
|
DBCO-Sulfo-Cy5
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Fluorescent Dye
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Others
|
|
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-155325
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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-
- HY-D1318
-
|
|
Fluorescent Dye
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Others
|
|
Cyanine7.5 azide chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with an azide functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Cyanine7.5 azide chloride can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cyanine7.5 azide chloride can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-117695
-
|
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
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Fluorescent Dye
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Others
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AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
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-
- HY-D2563
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG10000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D1298
-
|
|
Fluorescent Dye
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Others
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Dye 40 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-136247
-
|
Tyramide-Cy5
|
DNA Stain
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Others
|
|
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
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-
- HY-D1567
-
|
|
Fluorescent Dye
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Others
|
|
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
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-
- HY-D1366A
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cyanine5.5 carboxylic acid potassium is a fluorescent dye with excitation/emission wavelengths at 673/707 nm. The introduction of the sulfite group enhances the hydrophilic properties of the compound. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC and HATU, to form stable amide bonds.
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-
- HY-D1381
-
|
|
Fluorescent Dye
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Others
|
|
CH1055-PEG is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D0211R
-
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|
Fluorescent Dye
Reference Standards
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Others
|
|
Phenolphthalein (Standard) is the analytical standard of Phenolphthalein. This product is intended for research and analytical applications. Phenolphthalein is a widely applied but toxic indicator dye.
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-
- HY-D2432
-
-
- HY-D2028
-
|
|
Fluorescent Dye
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Others
|
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ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
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-
- HY-D2848
-
|
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Fluorescent Dye
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Others
|
|
Chitosan-Cy5.5 (MW 2000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 2000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
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-
- HY-158726
-
|
|
Fluorescent Dye
Apoptosis
|
Cancer
|
|
Complex 3 is a fluorescent dithiocarbazate-copper complex with anticancer activity, which localizes to mitochondria. Complex 3 displays excitation/emission maxima of 455-495/535 nm, respectively. Complex 3 inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Complex 3 induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells. Complex 3 also induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in AsPC-1 cells. Complex 3 reduces tumor volume in an AsPC-1 mouse xenograft model .
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-
- HY-D2635
-
|
|
Fluorescent Dye
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Others
|
|
Cy3 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
|
-
- HY-D2485
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo Cy3 bis COOH is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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-
- HY-101013
-
|
S-Nitroso-N-acetylpenicillamine
|
Fluorescent Dye
|
Others
|
|
D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.
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-
- HY-D1682
-
|
|
Fluorescent Dye
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Others
|
|
NFQ1 is a non-fluorescent quencher (absorption wavelength: 474 nm), and is used for a new type of One Sample Fluorescence Resonance Energy Transfer (OS-FRET) method. OS-FRET enable measurement of unquenched donor emission in the same sample. NFQ1 shows broad absorption spectrum ensuring its utility as a dark acceptor for many donors .
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-
- HY-P2270Y
-
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Arp2/3 Complex
Fluorescent Dye
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Others
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Phalloidin-TRITC (solution) is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
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-
- HY-115749A
-
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(Rac)-6′-Methoxyluciferin sodium
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Drug Derivative
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Others
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D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .
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-
- HY-105047
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NRL972
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Biochemical Assay Reagents
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Metabolic Disease
|
|
Fluorescein lisicol is a fluorescent-labelled bile salt and a marker of hepatic biliary transporter function. Fluorescein lisicol can be used for metabolic research .
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-
- HY-D1608
-
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Calcium Channel
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Others
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BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells .
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- HY-D2074
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Fluorescent Dye
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Others
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ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
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- HY-D1054
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Cyanine2 (iodine)
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Fluorescent Dye
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Others
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Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D2011
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Fluorescent Dye
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Others
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ATTO 565 hydrazid is a hydrazide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
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-
- HY-D1601
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Fluorescent Dye
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Others
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N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm . N-Aminofluorescein can be used to measure the concentration of copper ions in cells .
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- HY-D2144
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Fluorescent Dye
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Others
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Cy5-PEG7-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-D2021
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Fluorescent Dye
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Others
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|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
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- HY-137073
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Fluorescent Dye
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Others
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Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .
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- HY-D1845
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Fluorescent Dye
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Others
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|
Cy3B is an improved variant of the Cy3 (Cyanine3) (HY-D0822) dye. Cy3 is a fluorescent dye, and its fluorescence spectrum generally falls within the green to orange wavelength range .
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- HY-W099490
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Fluorescent Dye
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Others
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|
Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate is a fluorescent dye that can be used for generation of chemiluminescence .
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![Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate](//file.medchemexpress.com/product_pic/hy-w099490.gif)
- HY-D1894
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Fluorescent Dye
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Others
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5-Br-PAPS is a highly specific Zn 2+ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn 2+ by forming a deeply colored red Zn 2+ complex .
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-
- HY-P1002
-
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Suc-LLVY-AMC
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Fluorescent Dye
Proteasome
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Others
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|
Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
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- HY-D0819
-
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Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
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Fluorescent Dye
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Others
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|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
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- HY-U00452
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-
- HY-D2163
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Fluorescent Dye
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Others
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|
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-DY1015
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Fluorescent Dye
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Others
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Dihydroethidium (solution) , also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
Solvent and concentration: DMSO: 5 mM
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- HY-D2039
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Fluorescent Dye
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Others
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|
ATTO 550 cadaverin is a cadaverine derivative of ATTO 550, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 554/576 nm.
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- HY-172284
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Fluorescent Dye
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Others
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|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
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- HY-D2520
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Fluorescent Dye
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Others
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Cy3-PEG5000-biotin is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy3-PEG5000-biotin plays an important role in the specific capture and detection of biomolecules .
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- HY-D2623
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Fluorescent Dye
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Others
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|
Cy3 HA (MW 7000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-D0814
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4',6-Diamidino-2-phenylindole dihydrochloride
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DNA Stain
Sodium Channel
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Neurological Disease
|
|
DAPI (4',6-Diamidino-2-phenylindole) dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
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- HY-D2254
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Fluorescent Dye
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Others
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|
CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells .
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- HY-D1168
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Environmental Pollutants
Fluorescent Dye
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Metabolic Disease
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|
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .
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-
- HY-D0940
-
H2DCFDA
Maximum Cited Publications
747 Publications Verification
DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate
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Fluorescent Dye
Reactive Oxygen Species (ROS)
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Others
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|
H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) .
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- HY-D0052
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Fluorescent Dye
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Others
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|
5(6)-Carboxyeosin-diacetate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0721
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6-Carboxyfluorescein diacetate
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Fluorescent Dye
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Others
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|
6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
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- HY-D1531
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-
- HY-D2146
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Fluorescent Dye
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Others
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|
Cy5-PEG3-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-128868J
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Biochemical Assay Reagents
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Others
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FITC-Dextran (MW 1000) is a compound that belongs to the class of fluorescent dyes. It is often used as a tracer molecule in biomedical research to label and track cells or other biological substances. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate extracted from starch. The combination of the two creates a stable fluorescent tracer that can be observed under a microscope or quantified using specialized detection instruments.
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- HY-DY1065
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Fluorescent Dye
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Others
|
CY7 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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-
- HY-DY1034
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|
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Fluorescent Dye
|
Infection
Neurological Disease
|
4-MUNANA (solution) is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
Solvent and Concentration: Sterile water: 10 mM
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-
- HY-100041R
-
|
Monobromobimane (Standard)
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Fluorescent Dye
Reference Standards
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Others
|
|
Bromobimane (Standard) is the analytical standard of Bromobimane (HY-100041). This product is intended for research and analytical applications. Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
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- HY-D1917
-
|
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Fluorescent Dye
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Others
|
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
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-
- HY-D2845A
-
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Fluorescent Dye
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Others
|
|
4-Arm-PEG5000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG5000-FITC can be used for fluorescent labeling and imaging .
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-
- HY-W010947
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|
Fluorescent Dye
|
Inflammation/Immunology
|
|
4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .
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- HY-W356117
-
|
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Fluorescent Dye
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Others
|
|
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity .
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-
- HY-D2912
-
|
|
Biochemical Assay Reagents
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Others
|
|
Cys-shift probe-1 (compound 13) is a potent Cys-shift probe. Cys-shift probe-1 can improve the ion mobility of labeled peptides and be used in protein analysis .
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-
- HY-D1849
-
|
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Fluorescent Dye
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Others
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
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- HY-D1558
-
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|
Fluorescent Dye
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Others
|
|
1,3,5,7-Tetramethyl-2,6-diiodo-C3-SE-BODIPYs is a fluorescent dye, and a BODIPY derivative .
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- HY-D1761
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Fluorescent Dye
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Others
|
|
Fura-4F pentapotassium is a cell-impermeant fluorescent indicator for intracellular calcium ion measurement.
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- HY-D2842A
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG1000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG1000-biotin can be used for fluorescent labeling and imaging .
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- HY-D1565
-
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|
Fluorescent Dye
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Others
|
|
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D1986
-
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Fluorescent Dye
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Others
|
|
ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
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- HY-155326
-
|
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Fluorescent Dye
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Others
|
|
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-D1119C
-
|
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Fluorescent Dye
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Others
|
|
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.) .
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-
- HY-D2422A
-
-
- HY-D0933
-
-
- HY-D2667
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
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-
- HY-D2697
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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-
- HY-W800807
-
|
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Fluorescent Dye
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Others
|
|
R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-D1592
-
|
|
Fluorescent Dye
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Others
|
|
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
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-
- HY-D2054
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 alkin is an alkyne derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm. ATTO 532 alkin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-100575R
-
|
Acriflavinium chloride 3,6-Acridinediamine mix (Standard)
|
Fluorescent Dye
Reference Standards
HIF/HIF Prolyl-Hydroxylase
Bacterial
SARS-CoV
Monocarboxylate Transporter
Fungal
|
Infection
Cancer
|
|
Acriflavine (Standard) is the analytical standard of Acriflavine (HY-100575). This product is intended for research and analytical applications. Acriflavine (Acriflavinium chloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine is an antiseptic agent. Acriflavine is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2 .
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-
- HY-D0152
-
|
|
Fluorescent Dye
|
Others
|
|
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
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-
- HY-176031
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-2 potassium is a cell-impermeant fluorescent calcium indicator. Fluo-2 potassium binds calcium (Kd: 0.37 μM) with excitation/emission wavelengths of 493/518 nm, respectively .
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-
- HY-D1119
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
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-
- HY-139337
-
|
|
Fluorescent Dye
|
Others
|
|
SMCy5.5 is a SMCy dye (ex. 638 nm; em. 705 nm). The high brightness of SMCy5.5 allows for effective tracking and imaging of lipid droplet exchange between adipocytes. SMCy5.5 can be used for lipid droplet labeling studies .
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-
- HY-D0091
-
|
|
Fluorescent Dye
|
Others
|
|
7-Ethoxy-4-trifluoromethylcoumarin is a fluorescent substrate of various enzymes of the cytochrome P450 superfamily
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-
- HY-W179417
-
-
- HY-DY1062
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
Cy5.5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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-
- HY-D1880
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5 hydrazide is a fluorescent dye containing a hydrazide functionality (Ex/Em=646/662 nm) .
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-
- HY-D2017
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 554/576 nm.
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-
- HY-137845
-
|
|
Fluorescent Dye
|
Others
|
|
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .
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-
- HY-D2511
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG3400-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG3400-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-W739603
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-bifunctional dye potassium is a water soluble bifunctional dye possessing two terminal NHS ester functions. The NHS esters can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.
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-
- HY-D2223
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5 dUTP is a modified nucleoside triphosphate used for DNase labeling. Sulfo-Cy5 dUTP is a bright far-red emitting dye for the Cy5 channel .
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-
- HY-D3448
-
|
|
Fluorescent Dye
|
Others
|
|
8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .
|
-
- HY-D1737
-
|
|
Bacterial
|
Infection
|
|
RADA is a fluorescent D-amino acid (FDAA) with high photostability and thermostability, which emits yellow-to-orange fluorescence. RADA shows low outer membrane permeability in wild-type Gram-negative Escherichia coli, but it targets penicillin-binding proteins and L,D-transpeptidases, mimics the interaction between acyl acceptors and enzyme intermediates, and integrates into peptidoglycan during biosynthesis. As a peptidoglycan labeling reagent, RADA metabolically integrates into the nascent peptidoglycan of live bacterial cells, labels the peptidoglycan at the poles and lateral walls of mycobacteria, and enables visualization of peptidoglycan synthesis and remodeling processes. RADA serves as a non-specific stain for fixed cells, is non-toxic to bacterial cells, and its red-shifted excitation/emission spectra reduce phototoxicity. RADA also supports virtual pulse-chase labeling experiments and stochastic optical reconstruction microscopy for sub-diffraction-limited imaging of bacterial cell walls .
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-
- HY-D2151
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
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-
- HY-D2145
-
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Fluorescent Dye
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Others
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|
Cy5-PEG2-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-D2106
-
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Fluorescent Dye
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Others
|
|
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
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-
- HY-D2436
-
|
|
Fluorescent Dye
Microtubule/Tubulin
Apoptosis
|
Cardiovascular Disease
Cancer
|
|
PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .
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-
- HY-101883
-
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Fluorescent Dye
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Others
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|
BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. BCECF-AM could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
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-
- HY-D2048
-
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|
Fluorescent Dye
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Others
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|
ATTO 532 streptavidin is a streptavidin derivative of ATTO 532, it can label protein or antibody, the maximum excitation/emission wavelength: 532/552 nm.
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-
- HY-D0259
-
|
Erythrosin extra bluish
|
Environmental Pollutants
Fluorescent Dye
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Others
|
|
Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
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-
- HY-W090090
-
|
Pyrromethene 546
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Fluorescent Dye
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Others
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|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
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- HY-101892R
-
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Fluorescent Dye
Reference Standards
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Others
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|
DiBAC4(3) (Standard) is the analytical standard of DiBAC4(3) (HY-101892). This product is intended for research and analytical applications. DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential.
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-
- HY-D2227
-
|
|
Autophagy
Apoptosis
|
Cancer
|
|
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
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-
- HY-W440914
-
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Fluorescent Dye
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Others
|
|
DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.
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-
- HY-W027544
-
|
7-Methoxycoumarin-4-acetic acid
|
Fluorescent Dye
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Others
|
|
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
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-
- HY-D1353
-
|
|
Fluorescent Dye
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Others
|
|
LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish .
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-
- HY-D2486
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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-
- HY-D1365A
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3(Me)COOH TEA is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .
|
-
- HY-D1686B
-
|
|
DNA Stain
|
Others
|
|
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .
|
-
- HY-D1641
-
|
|
Fluorescent Dye
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Others
|
|
5,5'-Dimethyl BAPTA tetrapotassium is a water-soluble, extracellular membrane metal chelator with relative selectivity for calcium ions .
|
-
- HY-D1433
-
|
|
Fluorescent Dye
|
Cancer
|
|
FITC-C6-LEHD-FMK, a fluorescently labeled caspase-9 inhibitor, can be used for detection of active caspase-9 in mammalian cells undergoing apoptosis. FITC-C6-LEHD-FMK provides a convenient means for sensitive detection of activated caspase-9 in living cells. Z-LEHD-FMK is a specific caspase-9 inhibitor .
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-
- HY-145385
-
|
|
Fluorescent Dye
|
Others
|
|
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca 2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .
|
-
- HY-R04602F
-
|
|
MicroRNA
|
Cancer
|
|
FAM-MicroRNA Mimic Negative Control is a FAM labeled FAM-MicroRNA Mimic Negative Control (HY-R04602). MicroRNA Mimic Negative Control is a miRNA mimic of 21-nucleotides, and can be used as a negative control. The sequence of MicroRNA Mimic Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
|
-
FAM-MicroRNA Mimic Negative Control
FAM-MicroRNA Mimic Negative Control
- HY-D1082
-
|
|
Fluorescent Dye
|
Others
|
|
5-DTAF is a fluorescein dye that directly react with polysaccharides and other alcohols in aqueous solution at pH ＞9. The maximum of the 5-DTAF emission profile is at a wavelength of 518 nm after excitation at 488 nm. 5-DTAF can be used for biomolecular labeling, protein detection, and cell imaging .
|
-
- HY-D1633
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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-
- HY-D2795
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG400-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG400-COOH can be used for fluorescent labeling and imaging .
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-
- HY-126831
-
SBFI-AM
3 Publications Verification
|
Fluorescent Dye
|
Others
|
|
SBFI-AM is a Na + selective fluorescent indicator. SBFI-AM shows selectivity for Na + over K + with Kd values of 6.7 and 166 mM, respectively (Ex = 340/380 nm; Em = 500 nm) .
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-
- HY-W878943
-
-
- HY-D2740
-
|
|
Fluorescent Dye
|
Others
|
|
ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
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-
- HY-D1628
-
-
- HY-W800769
-
|
|
Fluorescent Dye
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Others
|
|
BP Fluor 532 Azide Plus is a fluroescent agent with a terminal azide group. The fluroescent compound has a max absorption at 532 nm and emission at 554 nm. The BP Fluor 532 Azide Plus was designed with a copper-chelating system within its structure, enabling the formation of strong, active copper complexes that act as both reactant and catalyst in CuAAC reactions.
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-
- HY-P1004
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Luciferase (bacterial) catalyzes the oxidation of a long-chain aldehyde and reduced flavin mononucleotide. Luciferase (bacterial) protection against oxidative stress for bacterial luminescence .
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-
- HY-D1695
-
-
- HY-D2069
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 680 alkin is an alkyne derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
-
- HY-D0214R
-
|
|
Reference Standards
Influenza Virus
|
Others
|
|
Acid Red 94 sodium (Standard) is the analytical standard of Acid Red 94 sodium. This product is intended for research and analytical applications. Acid Red 94 sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Acid Red 94 sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antiviral activities .
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-
- HY-137098
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
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-
- HY-D2618
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG2000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG2000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).
|
-
- HY-110250
-
|
|
Fluorescent Dye
|
Others
|
|
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
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-
- HY-D2176
-
|
|
Fluorescent Dye
|
Others
|
|
AF 555 carboxylic acid is a derivative of the orange fluorescent dye AF 555. AF 555 carboxylic acid is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 555 exhibits average excitation wavelengths under green laser and red laser of 510 nm and 610 nm, respectively .
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-
- HY-D1934
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 is a new fluorescent dye with good photostability and maximum excitation/emission wavelength: 453/506 nm.
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-
- HY-D2414
-
-
- HY-131023
-
|
JF549, Maleimide TFA
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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-
- HY-D2080
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 iodacetamid is an iodoacetamide derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
|
-
- HY-D2562
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG5000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2845
-
|
|
Fluorescent Dye
|
Others
|
|
4-Arm-PEG2000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG2000-FITC can be used for fluorescent labeling and imaging .
|
-
- HY-132263
-
|
|
Fluorescent Dye
|
Others
|
|
FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
|
-
- HY-100045
-
|
4-Nitrophenylphosphorylcholine; 4-Nitrophenylphosphorylcholine; O-(4-Nitrophenylphosphoryl)choline
|
Endogenous Metabolite
|
Metabolic Disease
|
|
p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5.
|
-
- HY-D1067
-
|
|
Fluorescent Dye
|
Others
|
|
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
|
-
- HY-D1503
-
-
- HY-D2820
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7.5 (MW 75000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 75000) can be used for fluorescent labeling and imaging .
|
-
- HY-118320
-
|
Mordant orange 1
|
Fluorescent Dye
|
Others
|
|
Alizarine Yellow R (Mordant orange 1), Salicylic acid derivative (HY-B0167), is an azo dye. Alizarine Yellow R is used as a pH indicator and a biological stain in chemical examinations and dyeing industries .
|
-
- HY-B0883
-
|
|
Bacterial
Fluorescent Dye
Potassium Channel
DNA/RNA Synthesis
|
Infection
Neurological Disease
Cancer
|
|
3,6-Diaminoacridine hemisulfate is a multifunctional acridine compound. 3,6-Diaminoacridine hemisulfate is an acridine dye and also a DNA inserter. 3,6-Diaminoacridine hemisulfate is a potent broad-spectrum antibacterial agent. Its mechanism is to insert into bacterial DNA, interfering with replication and transcription, leading to bacterial lysis. 3,6-Diaminoacridine hemisulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine hemisulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus. Long-term exposure may induce skin cancer or other malignant tumors .
|
-
- HY-D0785
-
|
4-Fluoro-7-nitrobenzofurazan
|
Fluorescent Dye
|
Others
|
|
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .
|
-
- HY-D2494
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-DY1027
-
|
|
Fluorescent Dye
|
Cancer
|
Indocyanine green (Foxgreen) (solution) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2482
-
|
APG-1 AM
|
Fluorescent Dye
|
Neurological Disease
|
|
Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K +-sensitive fluorescent indicator and potassium ion indicator that exhibits minimal interference from Na + and pH at physiologically relevant intracellular levels. Asante potassium green-1 AM enables non-invasive monitoring and quantitative analysis of intracellular potassium ion concentration (ᵢ) . Its excitation/emission maxima are 525/545 nm, respectively.
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-
- HY-D2653
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
|
-
- HY-D2685
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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-
- HY-D0150A
-
|
|
Fluorescent Dye
|
Others
|
|
(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
|
-
- HY-135835
-
|
|
Fluorescent Dye
|
Others
|
|
6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide . 6-FAM-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1943
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 Amine is an amine derivative of ATTO 590, the maximum excitation/emission wavelength: 594/622 nm.
|
-
- HY-D2015
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 alkyne is an alkyne derivative of ATTO 488 and can be used to label proteins or antibodies.
|
-
- HY-15944
-
|
5(6)-Carboxytetramethylrhodamine
|
Fluorescent Dye
|
Others
|
|
5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).
|
-
- HY-D1114
-
|
|
Fluorescent Dye
|
Others
|
|
TFAX 488,SE dilithium is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,SE dilithium yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
|
-
- HY-D2081
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 alkin is an alkyne derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
|
-
- HY-D2250
-
|
|
Fluorescent Dye
|
Others
|
|
Disulfo-ICG carboxylic acid is a derivative of ICG dye. ICG (Indocyanine Green) is a NIR fluorescent dye .
|
-
- HY-D2531
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2681
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
|
-
- HY-D1933
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
- HY-155322
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-123645
-
|
|
Fluorescent Dye
|
Others
|
Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu 2+), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) .
Excitation/emission wavelength:
Conventional detection: 510/578 nm.
Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).
|
-
- HY-151710
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1322
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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-
- HY-D2754
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 550 acid is a vibrant orange-to-red fluorochrome with better performance t han other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light Fluors means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
- HY-D1863
-
|
|
Fluorescent Dye
|
Others
|
|
sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-100512R
-
|
Pentacarboxybenzene (Standard)
|
Reactive Oxygen Species (ROS)
Reference Standards
|
Others
|
|
Benzenepentacarboxylic Acid (Standard) is the analytical standard of Benzenepentacarboxylic Acid (HY-100512). This product is intended for research and analytical applications. Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.
|
-
- HY-B1025
-
|
Lanadigenin
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .
|
-
- HY-W040291
-
|
|
Fluorescent Dye
|
Cancer
|
|
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. It is widely used for preparing bioconjugates of blue fluorescence.
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-
- HY-D2173
-
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Fluorescent Dye
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Others
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|
AF488 azide is a fluorescent dye that can be used to determine the reactivity of immobilized DIBO groups. AF488 azide exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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-
- HY-W400925
-
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Fluorescent Dye
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Others
|
|
Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-DY1107
-
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|
Fluorescent Dye
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Others
|
Halo tag TMR (solution) is a red fluorescent dye composed of Halo tag ligand molecules and TMR (TAMRA). Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity (Ex/Em = 550/576 nm) .
Solvent and concentration: DMSO: 5 mM
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-
- HY-D1176
-
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|
Fluorescent Dye
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Others
|
|
Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases .
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-
- HY-D1520
-
|
|
Phosphatase
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Others
|
|
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .
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-
- HY-D3300
-
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Fluorescent Dye
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Others
|
|
WSP2 (compound 7) is a turn-on fluoresonance probe that can be used for the detection of sulfane sulfur species .
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-
- HY-D1376A
-
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Fluorescent Dye
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Others
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|
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
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-
- HY-DY1029
-
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Fluorescent Dye
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Others
|
BODIPY-cholesterol (solution) is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
Solvent and concentration: DMSO: 1 mM
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-
- HY-D2801
-
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|
Fluorescent Dye
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Others
|
|
FITC-PEG400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG400-NHS can be used for fluorescent labeling and imaging .
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-
- HY-D1066
-
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|
Fluorescent Dye
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Others
|
|
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice .
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-
- HY-W998675
-
|
|
Fluorescent Dye
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Others
|
|
5-FITC-Tetrazine is an fluorescent dye composed of FITC (HY-66019) and Tetrazine. 5-FITC-Tetrazine can be used for fluorescent labeling and imaging .
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-
- HY-D1346
-
|
|
Fluorescent Dye
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Others
|
|
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.
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-
- HY-130210
-
|
|
Fluorescent Dye
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Others
|
|
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.
|
-
- HY-D1374
-
|
|
Fluorescent Dye
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|
|
Sulfo-Cy5 carboxylic acid potassium is a water-soluble, inactive Cy5 carboxylic acid.
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-
- HY-D0058
-
|
|
Fluorescent Dye
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Others
|
|
3,3'-Dipropylthiacarbocyanine (iodide) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W879007
-
|
|
Fluorescent Dye
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Others
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
|
-
- HY-D2836B
-
|
FITC-Hyaluronate (MW 200000)
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Fluorescent Dye
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Others
|
|
FITC-HA (MW 200000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
-
- HY-D2608
-
|
|
Fluorescent Dye
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Others
|
|
ICG PEG10000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG10000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
-
- HY-D1029
-
-
- HY-D2108
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2798C
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG10000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG10000-SH can be used for fluorescent labeling and imaging .
|
-
- HY-D0121B
-
|
|
Fluorescent Dye
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Others
|
|
INDO 1 pentasodium is a cell-impermeant ratiometric, free calcium ion (Ca 2+) fluorescent indicator that can quantitatively monitor dynamic changes in intracellular free Ca 2+ concentrations. When unbound to Ca 2+ (free state), INDO 1 pentasodium exhibits a peak emission wavelength of 485 nm under UV excitation (350 nm). Upon binding to Ca 2+ (bound state), the emission peak shifts to 405 nm. INDO 1 pentasodium is highly photolabile and susceptible to photobleaching, and its emission spectrum may overlap with the autofluorescence of NADH .
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-
- HY-D2652
-
|
|
Fluorescent Dye
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Others
|
|
Cy5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
|
-
- HY-D0073
-
|
|
Fluorescent Dye
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Others
|
|
2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2− to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively .
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-
- HY-D1081
-
|
|
Fluorescent Dye
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Others
|
|
6-DTAF hydrochloride is a fluorescein that can be used to label peptides and nucleotides .
|
-
- HY-D1630
-
|
|
Fluorescent Dye
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Others
|
|
4-Di-10-ASP is a fluorescent lipophilic tracer (Excitation 485 nm; Emission 620 nm). 4-Di-10-ASP can be used to stain phospholipid membranes in a specific manner .
|
-
- HY-D2680
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 200000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-D1847
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 tetrazine tetrafluoroborate is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a tetrazine group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Cy7.5 tetrazine tetrafluoroborate can perform efficient click reactions with molecules containing alkyne functional groups (such as alkyne) to form covalent bonds. It can be combined with biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2541
-
|
|
Fluorescent Dye
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Others
|
|
Cy5-PEG1000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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-
- HY-D1900
-
|
|
Fluorescent Dye
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Others
|
|
VIC azide, 6-isomer is a VIC derivative that can be used for conjugating VIC to other molecules. VIC can be used for labeling oligonucleotides at the 5’-end .
|
-
- HY-D0101A
-
|
|
Fluorescent Dye
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Others
|
|
Fluorescein-diphosphat (ammonium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-151690
-
|
|
Fluorescent Dye
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Others
|
|
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
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-
- HY-D2764
-
|
|
Fluorescent Dye
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Others
|
|
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
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-
- HY-D2036
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 550 iodacetamid is an iodoacetamide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
-
- HY-D2059
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
- HY-169130
-
|
|
Fluorescent Dye
|
Cancer
|
|
Lyso BD-1, preferentially colocalized in lysosomes and lipid droplets, displays excellent photocytotoxicity (5.57 μM) on triple negative breast cancer cells under white light. Lyso BD-1 displays emission band at 560nm .
|
-
- HY-D2205
-
|
Cy7 TSA
|
Fluorescent Dye
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Others
|
|
Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
|
-
- HY-D2498
-
|
|
Fluorescent Dye
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Others
|
|
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
|
-
- HY-D2030
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 514 streptavidin is a streptavidin derivative of ATTO 514, it can label protein or antibody, the maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-DY1076
-
|
|
Fluorescent Dye
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Others
|
BODIPY TR Cadaverine (solution) , a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-D2138
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-DY1022
-
|
|
Ferroptosis
Fluorescent Dye
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
BODIPY 581/591 C11 (solution) is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype) , or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-D2058
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
- HY-D2854E
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG10000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).
|
-
- HY-D1376
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
|
-
- HY-W748361
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
|
-
- HY-D1446
-
|
|
Fluorescent Dye
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Others
|
|
3′,6′-Bis(allyloxy)-Fluoran is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1312
-
|
|
Biochemical Assay Reagents
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Others
|
|
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
|
-
- HY-W320397
-
|
|
Fluorescent Dye
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Others
|
|
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.
|
-
- HY-D1920
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 390 azide is an azide derivative of ATTO 390 with excitation/emission maxima at 390/476 nm. ATTO 390 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172721
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
|
-
- HY-151712
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.
|
-
- HY-D0016
-
|
CTC
|
Fluorescent Dye
|
Cancer
|
|
5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm .
|
-
- HY-D2241
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
|
-
- HY-DY1041
-
|
|
Fluorescent Dye
|
Others
|
CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-DY1093
-
|
Thioflavin S (solution); Direct Yellow 7 (solution)
|
Fluorescent Dye
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Others
|
Thioflavine S (solution) (Thioflavin S (solution)) is a fluorescent histochemical marker of dense core senile plaques. Thioflavine S can be used for Alzheimer's research .
Solvent and concentration: ddH2O: 10 mg/mL
|
-
- HY-D1519
-
-
- HY-W800702
-
|
|
Fluorescent Dye
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Others
|
|
BP Fluor 555 Azide is a water-soluble, bright orange-fluorescent dye with excitation ideally suited for the 532 nm or 555 nm laser lines and visualized with TRITC (tetramethylrhodamine) filter sets. BP Fluor 555 conjugates of antibodies, peptides, and proteins are pH insensitive from pH 4 to pH 10. AF 555 conjugates ideally suited for detection of low abundance targets.
BP Fluor 555 Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. The brightness and photostability of this dye are best suited to direct imaging of low-abundance targets.
|
-
- HY-D2076
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
|
-
- HY-D1846
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-159194
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .
|
-
- HY-D1980
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 Carboxy is a carboxyl derivative of ATTO 620, the maximum excitation/emission wavelength is: 620/642 nm.
|
-
- HY-D0122
-
|
|
Fluorescent Dye
|
Others
|
|
6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .
|
-
- HY-D1915
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy.
|
-
- HY-D2802B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2329
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
|
-
- HY-D0135
-
|
|
Fluorescent Dye
|
Others
|
|
12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye .
|
-
- HY-172286
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 NHS ester is a fluorescent dye that can be used for fluorescent imaging study.
|
-
- HY-D0167
-
|
|
Fluorescent Dye
|
Others
|
|
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
|
-
- HY-D2766
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
- HY-D0918
-
|
|
Fluorescent Dye
|
Others
|
|
YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/530±30 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells .
|
-
- HY-129547
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-3 pentapotassium is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 pentapotassium itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
|
-
- HY-D2251
-
-
- HY-D1324
-
|
|
Fluorescent Dye
|
Others
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|
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
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- HY-D2674
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 7000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2761
-
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Fluorescent Dye
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Others
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DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
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- HY-D0121
-
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Fluorescent Dye
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Others
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INDO 1 is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
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- HY-D1389
-
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Sulfo-Cyanine5.5 NHS ester tripotassium
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Fluorescent Dye
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Others
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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- HY-D2592
-
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Fluorescent Dye
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Others
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|
Cy7.5-PEG1000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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- HY-D1750
-
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Fluorescent Dye
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Others
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Rhodamine B thiolactone is a high-sensitive Hg 2+ indicator used for measuring Hg 2+ concentration.
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- HY-DY1064
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Fluorescent Dye
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Others
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CY5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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- HY-D2517
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Fluorescent Dye
Liposome
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Others
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Cy3-PEG5000-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2083
-
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Fluorescent Dye
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Metabolic Disease
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BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments (Ex/Em = 540/580 nm) .
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- HY-D2238
-
-
- HY-D1461
-
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Fluorescent Dye
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Cancer
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|
Fluorescein Di-β-D-Glucopyranoside is a specific β-glucocerebrosidase substrate that can be used for the intralysosomal β-galactosidase .
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- HY-175046
-
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Fluorescent Dye
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Others
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C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0) (Lissamine-rhodamine B-dodecanoyl Galactosylceramide) is a fluorescently labeled version of C12 galactosylceramide.
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- HY-D2622
-
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Fluorescent Dye
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Others
|
|
Cy3 HA (MW 3000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-D2840A
-
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Fluorescent Dye
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Others
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|
FITC-mPEG550 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG550 can be used for fluorescent labeling and imaging .
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- HY-D2516
-
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Fluorescent Dye
Liposome
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Others
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|
Cy3-PEG3400-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2198
-
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Fluorescent Dye
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Others
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|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
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- HY-DY1047
-
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DNA Stain
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Others
|
DFHBI-1T (solution) is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
Solvent and concentration: DMSO: 20 mM
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-
- HY-126774
-
DAF-FM
1 Publications Verification
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Fluorescent Dye
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Others
|
|
DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .
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- HY-101901
-
-
- HY-D2121
-
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Fluorescent Dye
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Others
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Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D2801A
-
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Fluorescent Dye
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Others
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FITC-PEG1000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG1000-NHS can be used for fluorescent labeling and imaging .
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- HY-D2757
-
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Fluorescent Dye
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Others
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|
5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm.
The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
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- HY-D2552
-
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Fluorescent Dye
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Others
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Cy5.5-PEG1000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG1000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
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- HY-D1550
-
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Fluorescent Dye
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Others
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10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a fluorescent dye for Cu 2+ ion .
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- HY-D1262
-
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Thiol-green 2
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Fluorescent Dye
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Others
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|
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols . Ex: 490 nM; Em: 515 nM.
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- HY-D2826D
-
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Fluorescent Dye
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Others
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FITC-Chitosan (MW 5000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 5000) can be used for fluorescent labeling and imaging .
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- HY-D145729F
-
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Fluorescent Dye
STAT
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Cancer
|
|
FAM-Danvatirsen is a FAM-labeled Danvatirsen (HY-145729). Danvatirsen is an antisense oligonucleotide targeting STAT3 that can be used in the study of cancer .
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- HY-D1463
-
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Fluorescent Dye
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Others
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|
Nile Blue Methacrylamide is a pH-responsive probe. Nile Blue Methacrylamide exhibits pH-sensitive absorption and fluorescence emission in the physiological pH range, with spectral shifts occurring between acidic and near-physiological pH conditions . (Ex/Em = 590/670-700 nm)
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-
- HY-111263
-
NIAD-4
1 Publications Verification
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Fluorescent Dye
Amyloid-β
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Others
|
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NIAD-4 is a blood-brain barrier permeable fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM .
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- HY-147114
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Fluorescent Dye
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Others
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3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm .
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-
- HY-D0092R
-
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Reference Standards
Cytochrome P450
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Others
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|
7-Ethoxy-4-methylcoumarin (Standard) is the analytical standard of 7-Ethoxy-4-methylcoumarin. This product is intended for research and analytical applications. 7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .
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-
- HY-131461
-
-
- HY-D0981
-
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Coumarin 151; AFC
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Fluorescent Dye
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Others
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7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.
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- HY-D2020
-
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Fluorescent Dye
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Others
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|
ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
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- HY-D2709
-
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Fluorescent Dye
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Others
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|
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-D2800A
-
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Fluorescent Dye
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Others
|
|
FITC-PEG1000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG1000-MAL can be used for fluorescent labeling and imaging .
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- HY-D1585
-
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Fluorescent Dye
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Others
|
|
BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo .
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- HY-D2003
-
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Fluorescent Dye
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Others
|
|
ATTO 565 biotin is a biotin derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
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-
- HY-D2158
-
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Fluorescent Dye
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Others
|
|
Cy5-PEG7-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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-
- HY-D2582
-
|
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Fluorescent Dye
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Infection
|
|
DMAO is a membrane-permeable DNA fluorescent dye stains live and dead bacteria. (Ex/Em = 490/540 nm) .
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-
- HY-D2438
-
|
|
Fluorescent Dye
|
Cancer
|
|
CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
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- HY-D1544
-
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Fluorescent Dye
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Others
|
|
Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM) .
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-
- HY-15943
-
6-TAMRA
1 Publications Verification
6-Carboxytetramethylrhodamine
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Fluorescent Dye
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Others
|
|
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .
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-
- HY-D1699
-
|
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Fluorescent Dye
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Others
|
|
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .
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-
- HY-D0830
-
|
Fluorexon tetraethyl ester
|
Fluorescent Dye
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Others
|
|
Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
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-
- HY-D2483
-
|
APG-1 (TMA)
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Fluorescent Dye
|
Neurological Disease
|
|
Asante potassium green-1 (APG-1) TMA is a cell-impermeable K + (potassium) sensitive fluorescent indicator (excitation/emission = 525/545 nm) .
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- HY-DY1036
-
|
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Fluorescent Dye
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Cancer
|
Calcein AM (solution) , has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein) , which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-D1606
-
|
|
Adrenergic Receptor
|
Metabolic Disease
|
|
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with Ki values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes .
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-
- HY-D1762
-
-
- HY-D1119A
-
|
|
Fluorescent Dye
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Others
|
|
AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
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-
- HY-D1483
-
|
|
Fluorescent Dye
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Others
|
|
3,3-Dibutylthiacarbocyanine iodide is a fluorescent dye with an excitation of 559 nm and an emission 604 nm .
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-
- HY-D0092
-
|
|
Cytochrome P450
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Others
|
|
7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .
|
-
- HY-D0044
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Carboxy-X-rhodamin N-succinimidyl ester is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D1571
-
|
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DNA Stain
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Others
|
|
CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms .
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-
- HY-D2669
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
|
-
- HY-D2490
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-N3 is a Sulfo Cy5.5-azide, which is a fluorescent dye. Sulfo Cy5.5-N3 can be used in cell imagine by Click reaction. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2536
-
|
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Fluorescent Dye
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Others
|
|
Cy5-PEG10000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D2707
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-114491
-
|
|
ERK
Raf
|
Cancer
|
|
Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF .
|
-
- HY-W591335
-
|
Biotin-PEG5-alcohol
|
Biochemical Assay Reagents
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Others
|
|
Biotin-PEG5-OH (Biotin-PEG5-alcohol) is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.
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-
- HY-D2847B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
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-
- HY-D2854A
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG1000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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-
- HY-DY1012
-
|
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Fluorescent Dye
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Others
|
DiI (solution) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
Solvent and concentration: DMSO: 5 mM
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-
- HY-D2006
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 azide is an azide derivative of ATTO 565 with excitation/emission maxima at 564/590 nm.
|
-
- HY-D2898
-
|
|
Fluorescent Dye
Enterovirus
|
Infection
|
|
Jun14157 is a fluorescence polarization probe that can specifically bind to the conserved allosteric site of enterovirus 2C proteins (Ex: 485/20; Em: 528/20). Jun14157 has Kd values of 2.3 μM, 1.4 μM, and 1.1 μM for EV-D68 2C, EV-A71 2C, and CVB3 2C, respectively. Jun14157 can be used in research related to enteroviruses .
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-
- HY-D1743
-
-
- HY-D1996
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 647 Biotin is a biotin derivative of ATTO 647 with maximum excitation/emission wavelengths: 630/651 nm.
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-
- HY-121941
-
|
|
Fluorescent Dye
|
Others
|
|
Epoxy Fluor 7 is a sensitive fluorescent substrate for soluble epoxide hydrolase (sEH) that can be used for human and mouse enzymes. Epoxy Fluor 7 is hydrolyzed to yield fluorescence used for monitoring the activity of sEH.
|
-
- HY-W800695
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 DBCO is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
|
-
- HY-D1049
-
|
6-((2,4-Dinitrophenyl)amino)hexanoic acid
|
Fluorescent Dye
|
Metabolic Disease
|
|
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
|
-
- HY-D0982
-
|
|
Fluorescent Dye
|
Others
|
|
Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
|
-
- HY-D1684
-
|
|
Amyloid-β
|
Neurological Disease
|
|
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λex/λem=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo .
|
-
- HY-D0012A
-
-
- HY-66020
-
6-FITC
1 Publications Verification
6-Fluorescein Isothiocyanate
|
Fluorescent Dye
Drug Isomer
|
Others
|
|
6-FITC (6-Fluorescein Isothiocyanate) is a fluorescein isomer and also serves as a fluorescent label for biomolecules (FITC isomers have similar excitation/emission wavelengths, which are 495 nm/519 nm in fluorescence detection) .
|
-
- HY-D2826A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Chitosan (MW 40000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 40000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2426
-
|
|
Fluorescent Dye
Transferrin Receptor
|
Cardiovascular Disease
|
|
Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron .
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- HY-D1726
-
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Deubiquitinase
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Cancer
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8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC50 close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .
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- HY-D1119B
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Fluorescent Dye
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Others
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AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
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- HY-D2026
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Fluorescent Dye
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Others
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ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
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- HY-D2840D
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Fluorescent Dye
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Others
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FITC-mPEG2000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG2000 can be used for fluorescent labeling and imaging .
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- HY-D0924
-
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Sulfo-Cyanine5.5
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Fluorescent Dye
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
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Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D0032
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DAF-2DA
2 Publications Verification
5,6-Diaminofluorescein diacetat
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Fluorescent Dye
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Others
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DAF-2DA (5,6-Diaminofluorescein diacetat) is most widely probe for NO measurement.
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- HY-D3012
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Fluorescent Dye
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Others
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12-AS is a 9-anthracenoxy fatty acid probe. 12-AS’s fluorescence decay is not a single index, and its lifetime increases with the red shift of the emission wavelength .
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- HY-D1272
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Sulfo-Cyanine3 amine
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Fluorescent Dye
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Others
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Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-173643
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Biotin-C6:0-gm3 ammonium; N-Hexanoyl-biotin-monosialoganglioside gm3 ammonium
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Drug Derivative
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Metabolic Disease
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C6 Biotin ganglioside gm3 (d18:1/6:0) (Biotin-C6:0-gm3) ammonium is a derivative of ganglioside GM3. C6 Biotin ganglioside gm3 (d18:1/6:0) ammonium can be used to detect or immobilize ganglioside GM3 through interaction with the biotin ligand .
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- HY-D2700
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Fluorescent Dye
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Others
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Cy7.5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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- HY-W338079
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Caspase
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Others
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Ac-Asp-Glu-Val-Asp-pNA is a peptidic substrate of caspase-3/7 .
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- HY-D0035
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Fluorescent Dye
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Others
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MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .
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- HY-D1040A
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Cyanine 5.5 carboxylic acid chloride
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Fluorescent Dye
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Others
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Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis .
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- HY-DY1039
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Fluorescent Dye
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Others
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DiBAC4 (3) (solution) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4 (3) can be used to measure cell membrane potential.
Solvent and concentration: DMSO: 10 mM
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- HY-D1861
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Fluorescent Dye
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Others
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Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-101889
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-
- HY-D2174
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Fluorescent Dye
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Others
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AF488 amine is a bright, green-fluorescent dye used for labeling molecule such as antibodies. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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- HY-D1473
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-
- HY-D2654
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Fluorescent Dye
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Others
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Cy5 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
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- HY-D0968B
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Cyanine3 triethylamine
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Fluorescent Dye
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Others
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Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
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- HY-D2112
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Fluorescent Dye
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Others
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TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1482A
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Fluorescent Dye
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Others
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Sulfo Cy5-tetrazine sodium is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine sodium is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-D1956
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Fluorescent Dye
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Others
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ATTO 594 Alkin is an alkyne derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
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- HY-D1676
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Phosphatase
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Others
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Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
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- HY-D2508
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Fluorescent Dye
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Others
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Cy3-PEG10000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG10000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
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- HY-D2388
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Fluorescent Dye
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Others
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Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-D2760
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Fluorescent Dye
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Others
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BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
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- HY-D1987
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Fluorescent Dye
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Others
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ATTO 620 Streptavidin is a streptavidin derivative of ATTO 620, it can label protein or antibody, the maximum excitation/emission wavelength: 620/642 nm.
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-
- HY-D2062
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Fluorescent Dye
Integrin
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Cancer
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ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
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- HY-D1629
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Fluorescent Dye
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Others
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Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles .
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-
- HY-W415108
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Fluorescent Dye
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Others
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10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate is an acridinium ester that produces fluorescent 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfate, and other oxidants under alkaline conditions. 10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate can be used in chemiluminescent assays, enzyme, antigen, antibody, and hormone immunoassays, and for the detection of oxidants in environmental, biological, and pharmaceutical samples .
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-
- HY-DN0194F
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Fluorescent Dye
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Others
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Cy3-Asiatic acid is a fluorescent labeling reagent that combines Cy3 (HY-D0822) and Asiatic acid (HY-N0194). Cy3-Asiatic acid can be used to observe and track Asiatic acid under fluorescence microscopy (Ex/Em = 550/570 nm).
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-
- HY-D1098
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Fluorescent Dye
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Others
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SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .
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-
- HY-D2875
-
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Fluorescent Dye
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Others
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|
5-FITC tyramide is a green fluorescent dye composed of FITC (HY-66019) and tyramide (Ex=488 nm, Em=525 nm). 5-FITC tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .
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-
- HY-D0983
-
-
- HY-D2656
-
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Fluorescent Dye
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Others
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|
Cy5.5 HA (MW 3000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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-
- HY-W440914B
-
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Fluorescent Dye
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Others
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|
DSPE-PEG10000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG10000-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .
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-
- HY-D2738
-
|
|
Fluorescent Dye
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Others
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|
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
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-
- HY-D2045
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Fluorescent Dye
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Others
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ATTO 532 carboxy is a carboxyl derivative of ATTO 532, the maximum excitation/emission wavelength is: 532/552 nm.
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-
- HY-D2179
-
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|
Fluorescent Dye
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Others
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|
AF 568 DBCO is a fluorescent dye that reacts with azide-labeled molecules or biomolecules via copper-free click chemistry. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
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-
- HY-D1574
-
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Fluorescent Dye
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Others
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|
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
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-
- HY-D2750
-
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|
Fluorescent Dye
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Others
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Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
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-
- HY-D0226
-
|
1,4-Dihydroxyanthraquinone
|
DNA/RNA Synthesis
Fungal
|
Infection
Cancer
|
|
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .
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-
- HY-D2651
-
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Fluorescent Dye
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Others
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|
Cy5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
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-
- HY-D2014
-
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|
Fluorescent Dye
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Others
|
|
ATTO 565 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 alkyne is an alkyne derivative of ATTO 565 and can be used to label proteins or antibodies.
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-
- HY-D2168
-
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Fluorescent Dye
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Others
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|
AF 568 azide is an azide derivative of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
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-
- HY-D2763
-
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|
Fluorescent Dye
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Others
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|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
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-
- HY-136277
-
DFHO
1 Publications Verification
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Fluorescent Dye
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Others
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|
DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells .
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-
- HY-D1118
-
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|
Fluorescent Dye
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Others
|
|
BODIPY 576/589 is a long wavelength biological labeled dye contains a free COOH-group (Em/Ex = 589/576 nm) .
|
-
- HY-D1746
-
EDTA-AM
2 Publications Verification
EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
|
Biochemical Assay Reagents
Mitosis
|
Others
|
|
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .
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-
- HY-D0107
-
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Fluorescent Dye
|
|
|
Fluorescein dicaproate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
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-
- HY-D0936
-
|
|
Fluorescent Dye
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Others
|
|
SPQ is a fluorescent dye. SPQ can be used to measure chloride ion concentration transients and transport rates in vesicles, cells, and even intact epithelium .
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-
- HY-135239
-
|
|
Fluorescent Dye
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Others
|
|
Fura-FF pentapotassium is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration) .
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-
- HY-D2816
-
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Fluorescent Dye
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Others
|
|
Chitosan-Cy7.5 (MW 2000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 2000) can be used for fluorescent labeling and imaging .
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-
- HY-107864R
-
|
Tetraiodofluorescein (Standard)
|
Reference Standards
Fluorescent Dye
|
Infection
|
|
Erythrosine B free acid (Standard) is the analytical standard of Erythrosine B (free acid) (HY-107864). This product is intended for research and analytical applications. Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .
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-
- HY-D2798B
-
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|
Fluorescent Dye
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Others
|
|
FITC-PEG5000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG5000-SH can be used for fluorescent labeling and imaging .
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-
- HY-D1588
-
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Fluorescent Dye
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Others
|
|
BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .
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-
- HY-D0367
-
|
Calcofluor White M2R
|
Fluorescent Dye
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Others
|
|
Fluorescent brightener 28 is a fluorescent whitening agent commonly used in the padding process of the textile industry. Fluorescent brightener 28 is capable of staining polysaccharides such as cellulose, and when the plasma membrane ruptures, it also weakly stains the cytoplasm and strongly stains the cell nucleus. Additionally, Fluorescent brightener 28 can be utilized to detect intracellular chitin in living cells. Fluorescent Brightener 28 also is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .
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-
- HY-D0036
-
|
4-Bromomethyl-7-methoxycoumarin
|
Fluorescent Dye
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Others
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|
Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is often used as fluorescent label for the determination of compounds possessing a carboxylic group. Br-Mmc is used for the determination fatty acids by TLC or HPLC .
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-
- HY-D0110A
-
|
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Fluorescent Dye
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Others
|
|
Fura-2 pentapotassium is a cell-impermeable scaled fluorescent dye that can be used for intracellular calcium imaging. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca 2+ level .
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-
- HY-D3315
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Fluorescent Dye
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Others
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Rhodamine B carbohydrazide is a fluorescent derivative based on Rhodamine B (HY-Y0016) that contains the spirocyclic structure of Rhodamine B; it can be used for the detection of copper ions (Cu 2+), mercury ions, peroxynitrite, hydroxyl radicals, and nitric oxide (NO).
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-
- HY-W297715
-
-
- HY-D2558
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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-
- HY-D2035
-
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|
Fluorescent Dye
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Others
|
|
ATTO 514 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 alkyne is an alkyne derivative of ATTO 514 and can be used to label proteins or antibodies.
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-
- HY-D1755
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Fluorescent Dye
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Others
|
|
Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca 2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg 2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.
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-
- HY-101937B
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Fluorescent Dye
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Others
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L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
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-
- HY-D1332
-
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Fluorescent Dye
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Others
|
|
BODIPY FL hydrazide hydrochloride is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-110213
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Fluorescent Dye
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Others
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BODIPY 630/650X is a red fluorescent dye that targets amine groups. BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively. BODIPY 630/650X can be used to covalently label proteins, antibodies, or other amine-containing biomolecules for detection and imaging .
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- HY-D1926
-
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Fluorescent Dye
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Others
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ATTO 425 Streptavidin is a streptavidin derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
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- HY-D2264
-
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Fluorescent Dye
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Others
|
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Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices .
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-
- HY-151537
-
|
|
Fluorescent Dye
|
Infection
Inflammation/Immunology
|
|
Gol-NTR is a Golgi-targetable probe with high selectivity and sensitivity. Gol-NTR is Nitroreductase (NTR)-activated and has visualization acute lung injury (ALI) and repair function. Gol-NTR has a low detection limit of 54.8 ng/mL. Gol-NTR can be used for the research for monitoring and assessing research response of sepsis-induced ALI .
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-
- HY-D1543
-
|
|
DNA Stain
|
Infection
|
|
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor .
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-
- HY-D1598
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-D1864
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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-
- HY-D2854B
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG2000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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-
- HY-D0108
-
|
|
Fluorescent Dye
|
|
|
Fluorescein dilaurate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
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-
- HY-175133
-
|
Biotin ceramide (t18:0/6:0)
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Fluorescent Dye
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Others
|
|
C6 Biotin phytoceramide (t18:0/6:0) is an affinity probe that allows C6 phytoceramide to be detected or immobilized through interaction with the biotin ligand .
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-
- HY-D1319A
-
|
Cy5 acid bromide
|
Fluorescent Dye
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Others
|
|
Cyanine5 carboxylic acid (bromide) is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm). Cyanine5 carboxylic acid chloride is an non-reactive dye that can be used in control samples .
|
-
- HY-66022
-
5-FAM
4 Publications Verification
5-Carboxyfluorescein
|
Fluorescent Dye
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Others
|
|
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .
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-
- HY-147171
-
-
- HY-D1250
-
|
|
Fluorescent Dye
|
Cancer
|
|
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
|
-
- HY-D2489
-
|
|
Fluorescent Dye
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Others
|
|
Cy5-tetrazine is a fluorescent dye. Cy5-tetrazine is a CY5 (HY-D0821) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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-
- HY-D2002
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-136865
-
|
|
Fluorescent Dye
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Others
|
|
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm) .
|
-
- HY-D0022A
-
|
6-AF
|
Fluorescent Dye
|
Others
|
|
6-Aminofluorescein (6-AF) is a fluorescent labeling reagent. 6-Aminofluorescein can be used to label fullerene-based liposome nanostructures termed ‘buckysomes′ (Ex/Em = 490/515 nm) .
|
-
- HY-D2103
-
|
|
Fluorescent Dye
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Others
|
|
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
|
-
- HY-D0397
-
|
|
Fluorescent Dye
|
Others
|
|
C.I. Direct Violet 9 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1562
-
|
|
Fluorescent Dye
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Others
|
|
CytoTrace Red CMTPX is a cell permeable long-term cell tracer (Ex=577 nm, Em=602 nm) .
|
-
- HY-D2047
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D1586
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
-
- HY-124013
-
|
4-(α-N-L-alanine)-NBD
|
Fluorescent Dye
|
Others
|
|
NBDA (4-(α-N-L-alanine)-NBD) is a structural and functional analogue of the 2,4-dinitrophenyl group (DNP). NBDA can be used to detect and characterize antinitroaromatic antibodies, even in crude preparations, and possibly on cell surfaces .
|
-
- HY-D2278
-
|
|
Fluorescent Dye
|
Others
|
|
GDP-Fucose-Cy5 is a fluorescent dye that can be used for labeling free glycans, glycoproteins and glycolipids .
|
-
- HY-D1050
-
|
6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
|
Fluorescent Dye
|
Metabolic Disease
|
|
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
|
-
- HY-D2248
-
|
|
Fluorescent Dye
|
Others
|
|
ICG-TCO is a fluorescent dye coupled by Indocyanine Green (ICG) and TCO. ICG-TCO can be used for detection and visualization of tetrazine-containing molecules.
|
-
- HY-D2800C
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG5000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG5000-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-DY1031
-
|
|
Fluorescent Dye
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Others
|
FM4-64 (solution) is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers.
Solvent and concentration: DMSO: 5 mM
|
-
- HY-103470
-
|
|
Fluorescent Dye
|
Others
|
|
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .
|
-
- HY-D1913
-
|
|
Fluorescent Dye
|
Others
|
|
Fe2Orange is a Fe 2+ selective probe with an excitation wavelength of 543 nm and an emission wavelength of 580 nm. Fe2Orange emits fluorescence after binding to intracellular Fe 2+, thereby achieving specific labeling of Fe 2+. Fe2Orange is used to detect the content and distribution of Fe 2+ in cells .
|
-
- HY-D2016
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 cadaverine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 cadaverine is a cadaverine derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-W923132
-
|
Acryloyloxy fluorescein
|
Fluorescent Dye
Endogenous Metabolite
|
Others
|
|
Fluorescein O-acrylate (Acryloyloxy fluorescein) is a highly efficient fluorescent monomer that exhibits strong quantum yield in aqueous solutions, with its excitation and emission wavelengths situated within the visible light spectrum. This versatile monomer can be copolymerized with various compounds, including styrene, and acrylamide, enhancing its ability to bond with macromolecules.
|
-
- HY-D1953
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Azide is an azide derivative of ATTO 594 with excitation/emission maxima at 603/626 nm.
|
-
- HY-W806655
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3.5 carboxylic acid is a fluorophore featuring a carboxylic acid. The carboxylic acid is readily attacked by amines to form a stable amide bond. Cy3.5 is a cyanine dye with excitation and emission maxima at 576 nm and 603 nm respectively.
|
-
- HY-D1730A
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-D2005
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 amine is an amine derivative of ATTO 565, the maximum excitation/emission wavelength: 564/590 nm.
|
-
- HY-120971
-
|
DepNA
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DepNA to FAAH activity results in the release of the yellow colorimetric dye p-nitroaniline (ε=13,500 at 410 nm). This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer.
|
-
- HY-W127769
-
|
Salmon-Gal
|
Fluorescent Dye
|
Others
|
|
Rose-β-D-Gal is a chromogenic substrate, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity .
|
-
- HY-D2553
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG3400-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG3400-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-101887R
-
|
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Calcein Blue (Standard) is the analytical standard of Calcein Blue (HY-101887). This product is intended for research and analytical applications. Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator .
|
-
- HY-D1959
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D2117
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1866
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D2200
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5(Me)-C3-DBCO is a click chemistry reagent containing an cycloalkynes group. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .
|
-
- HY-D1739
-
|
|
Fluorescent Dye
Carboxylesterase (CES)
|
Others
|
|
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.
|
-
- HY-D2854D
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
-
- HY-143285
-
|
|
Fluorescent Dye
|
Infection
|
|
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
|
-
- HY-D1937
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 Streptavidin is a streptavidin derivative of ATTO 465, the maximum excitation/emission wavelength: 453/506 nm.
|
-
- HY-D2569
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG2000-Biotin is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5.5-PEG2000-Biotin plays an important role in the specific capture and detection of biomolecules.
|
-
- HY-D1469
-
|
R6G-SE
|
Fluorescent Dye
|
Others
|
|
5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye .
|
-
- HY-D0233R
-
|
|
Reference Standards
Fluorescent Dye
|
Others
|
|
Leucocrystal violet (Standard) is the analytical standard of Leucocrystal violet (HY-D0233). This product is intended for research and analytical applications. Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.
|
-
- HY-D1939
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
|
-
- HY-D1936
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
-
- HY-172269
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D1871
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2434
-
|
|
Fluorescent Dye
|
Others
|
|
HRP-PEG-Cy3 is a HRP and Cy3 (HY-D0822) labeled PEG. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm.
|
-
- HY-D2244
-
-
- HY-D1997
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 663/680 nm.
|
-
- HY-D2670
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
|
-
- HY-D1967
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 Azide is an azide derivative of ATTO 520 with excitation/emission maxima at 630/651 nm.
|
-
- HY-D1053
-
|
Sulfo-Cyanine7-N3
|
Fluorescent Dye
|
Metabolic Disease
|
|
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W879342
-
-
- HY-D1337
-
|
|
Fluorescent Dye
|
|
|
Cyanine7 carboxylic acid chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-DY1049
-
|
|
Amyloid-β
|
Others
|
Thioflavin T (solution) is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) .
Solvent and Concentration: Sterile water: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D1905
-
|
|
Fluorescent Dye
|
Cancer
|
|
ICG acid is a fluorescent dye used in medical diagnostics. ICG acid has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue. ICG acid has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors .
|
-
- HY-135414
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-D1577
-
|
|
Fluorescent Dye
|
Cancer
|
|
C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research .
|
-
- HY-D2208
-
|
|
Fluorescent Dye
|
Others
|
|
SYTM Green is a cell impermeant DNA dye that fluoresces green by binding to dsDNA (Ex/Em=503/530 nm). SYTM Green can also be used to stain bacteria, including Gram-positive and Gram-negative bacteria. Note: SYTM Green cannot penetrate living cells, and this product is equivalent to (Ex/Em=488/530 nm) .
|
-
- HY-136936
-
|
|
Fluorescent Dye
|
Others
|
|
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
|
-
- HY-D1897
-
|
5′-Tetrachlorofluorescein phosphoramidite
|
Fluorescent Dye
|
Others
|
|
6-TET phosphoramidite (5′-Tetrachlorofluorescein phosphoramidite) is a fluorescent dye that can be used for labeling an oligonucleotide with fluorescein .
|
-
- HY-W027773
-
-
- HY-172285
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 hydrazide is a cyanine dye linker containing hydrazide, which can be used to label aldehydes and ketones. This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins after oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
|
-
- HY-D2710
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
-
- HY-W127716
-
|
|
Fluorescent Dye
|
Cancer
|
|
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
|
-
- HY-D2858
-
|
|
Fluorescent Dye
|
Others
|
|
8-Arm-PEG10000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-Arm-PEG10000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
-
- HY-D2291
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D2614
-
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Fluorescent Dye
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Others
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|
ICG PEG2000 biotin is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em=785/813 nm).
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-
- HY-D2842D
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG5000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG5000-biotin can be used for fluorescent labeling and imaging .
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-
- HY-P2270
-
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Fluorescent Dye
Arp2/3 Complex
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Others
|
|
Phalloidin-TRITC is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
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-
- HY-D1044
-
|
Rhodamine 640 chloride
|
Fluorescent Dye
|
Cancer
|
|
Rhodamine 101 chloride (Rhodamine 640 chloride) is a fluorescent dye with excitation and emission maxima at 565 nM and 595 nM, respectively. Rhodamine 101 chloride binds to intracellular proteins and emits specific fluorescence. Rhodamine 101 chloride can be used in colon cancer research .
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-
- HY-D1052
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D1442
-
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Fluorescent Dye
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Others
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|
SBFI (tetraammonium), the tetraammonium salt of SBFI, is a cell-impermeant sodium fluorescence indicator. SBFI (tetraammonium) is sodium-sensitive dye. The excitation wavelength is set 333 nm, and the emission wavelength is 539 nm for SBFI .
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-
- HY-D2745
-
|
|
Fluorescent Dye
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Others
|
|
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
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-
- HY-D2161
-
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Fluorescent Dye
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Others
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|
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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-
- HY-134435
-
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Fluorescent Dye
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Others
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|
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
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-
- HY-D2111
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Fluorescent Dye
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Others
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|
TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D0718
-
|
Nile Blue A oxazone; Phenoxazone 9
|
Fluorescent Dye
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Others
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|
Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm .
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-
- HY-D1316
-
|
|
Fluorescent Dye
|
|
|
Cyanine7 azide chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-158741
-
|
APG-2 Acetoxymethyl ester
|
Fluorescent Dye
Potassium Channel
|
Others
|
|
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .
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-
- HY-D2655
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
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-
- HY-D1969
-
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|
Fluorescent Dye
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Others
|
|
ATTO 700 Alkin is an alkyne derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm. ATTO 700 Alkin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D2140
-
|
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Fluorescent Dye
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Others
|
|
Cy3-PEG4-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 4 PEG units. Cy3-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D0059
-
|
DIB-Cl
|
Fluorescent Dye
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Others
|
|
4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC .
|
-
- HY-D0081A
-
-
- HY-D0399
-
|
|
Fluorescent Dye
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Others
|
|
C.I. Acid blue 40 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2497
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-114879
-
DDAO
1 Publications Verification
|
Fluorescent Dye
Carboxylesterase (CES)
|
Cancer
|
|
DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
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-
- HY-D2504
-
-
- HY-D2429
-
|
|
Fluorescent Dye
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Others
|
|
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
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-
- HY-D1962
-
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Fluorescent Dye
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Others
|
|
ATTO 633 Streptavidin is a streptavidin derivative of ATTO 633, it can label protein or antibody, the maximum excitation/emission wavelength: 630/651 nm.
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-
- HY-126839
-
|
5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
|
Fluorescent Dye
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Others
|
|
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
|
-
- HY-D2165
-
|
|
Fluorescent Dye
|
Others
|
|
AF 594 streptavidin is a bioconjugating agent. It consists of AF 594 and streptomycin, a streptomycin derivative of the red fluorescent dye AF 594. AF 594 has high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 streptavidin can be selectively conjugated to streptavidin-modified molecules via a streptomycin-modifying group for fluorescent labeling and spectroscopic analysis .
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-
- HY-D2031
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 biotin is a biotin derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
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-
- HY-D1112
-
|
|
Fluorescent Dye
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Others
|
|
TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies .
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-
- HY-D2599
-
|
|
Fluorescent Dye
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Others
|
|
ICG PEG1000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG1000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
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-
- HY-D2118
-
|
|
Fluorescent Dye
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Others
|
|
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D0162
-
|
MCCK1
|
Fungal
IKK
NF-κB
Apoptosis
|
Infection
Cancer
|
|
Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo .
|
-
- HY-W248587
-
-
- HY-D2538
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG3400-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D1885
-
|
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 647 Carboxylic acid free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivative is an inactive labeled fluorescent dye, which can be used to label proteins, antibodies, polysaccharides. The use of Vari Fluor carboxylic acid derivatives requires carboxylic acid activation.
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-
- HY-155323
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-W103047
-
|
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
|
1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells .
|
-
- HY-D2164
-
|
|
Fluorescent Dye
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Others
|
|
AF 430 alkyne is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via Alkyne groups and molecules containing Azide groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D2768
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
|
-
- HY-D1366
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine5.5 carboxylic acidCI Pigment violet 32 is a water-soluble, far-red emitting fluorophore. Due to its four sulfo groups, this dye has a negative charge at neutral pH and is very hydrophilic. As a cyanine dye, sulfo-Cyanine5.5 shows a very low dependence of fluorescence on pH and a very high extinction coefficient.
|
-
- HY-D1445
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
|
-
- HY-D1679
-
|
|
Fluorescent Dye
|
Others
|
|
Phalloidin-f-HM-SiR is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2023
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 streptavidin is a streptavidin derivative of ATTO 665, it can label protein or antibody, the maximum excitation/emission wavelength: 663/680 nm.
|
-
- HY-D2475
-
|
|
Fluorescent Dye
|
Others
|
|
2-Amino-5-methoxybenzamidoxime is a chemical probe for detection of ketone, including aromatic ketones, hydroxyl ketones, cyclic ketones and aliphatic ketones. 2-Amino-5-methoxybenzamidoxime exhibits an excitation maximal wavelength of 389 nm and a emission maximal wavelength of 515 nm .
|
-
- HY-W019823
-
|
|
Fluorescent Dye
|
Infection
Neurological Disease
|
|
4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
|
-
- HY-D2649
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
|
-
- HY-130916
-
|
5(6)-CarboxyrhodaMine 6G, succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
5(6)-CR6G,SE (5(6)-CarboxyrhodaMine 6G) is a trace fluorescent labeling reagent for fluorescence imaging of protein crystallization. 5(6)-CR6G,SE can efficiently bind to proteins to produce characteristic fluorescence under specific excitation conditions. 5(6)-CR6G,SE shows a peak absorption wavelength of approximately 525 nm and exhibits a peak fluorescence emission wavelength of around 550 nm when excited by a 530 nm green LED .
|
-
- HY-D1336
-
|
|
Fluorescent Dye
|
|
|
FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
|
-
- HY-D2751
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
|
-
- HY-D2643
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 50000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-156303
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
-
- HY-D1372
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-D2063
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
- HY-D2109
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2687
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
|
-
- HY-D2509
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2121A
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D1414
-
|
|
Fluorescent Dye
|
|
|
Cyanine 3 Bisfunctional MTSEA Dye potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-137834
-
|
|
Fluorescent Dye
|
Others
|
|
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .
|
-
- HY-D1620
-
-
- HY-D2619
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG5000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG5000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).
|
-
- HY-D1306
-
|
|
Drug Isomer
|
Others
|
|
TAMRA azide, 6-isomer is an isomer of TAMRA. TAMRA azide, 6-isomer is the linker of TAMRA.
|
-
- HY-D1627
-
|
CM-DiI
|
Fluorescent Dye
|
Others
|
|
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .
|
-
- HY-140938A
-
|
|
PROTAC Linkers
|
Cancer
|
|
(Rac)-Biotin-PEG3-oxyamine hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-123051
-
-
- HY-D2847A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
|
-
- HY-W269179
-
|
|
Fluorescent Dye
|
Cancer
|
|
4-Bromomethyl-6,7-dimethoxycoumarin is a fluorescent label for carboxylic acids in chromatographic detection .
|
-
- HY-D2611
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG3400 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG3400 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
-
- HY-D2660
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 50000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
-
- HY-138159
-
-
- HY-D1540
-
|
Cy 5.5 amine; LumiProbe Cy 5.5 amine
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-D1605
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm) .
|
-
- HY-D1580
-
|
|
Fluorescent Dye
|
Others
|
|
C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides .
|
-
- HY-W324458
-
|
|
Fluorescent Dye
|
Others
|
|
MCA succinimidyl ester is a derivative of MCA (HY-W027544). MCA succinimidyl ester has succinimidyl ester can react selectively with amines. MCA succinimidyl ester can be used as peptide substrate for fluorescence resonance energy transfer .
|
-
- HY-134566
-
|
|
Fluorescent Dye
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Others
|
|
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .
|
-
- HY-D2869
-
|
|
Fluorescent Dye
Drug Intermediate
|
Others
|
|
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .
|
-
- HY-101891
-
|
|
Fluorescent Dye
|
Others
|
|
Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in Vm .
|
-
- HY-D2613
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG10000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG10000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
-
- HY-D0716
-
|
Fluo-3-pentaacetoxymethyl ester
|
Fluorescent Dye
|
Others
|
|
Fluo-3 AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Fluo-3 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
-
- HY-133883
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .
|
-
- HY-D1524
-
|
1,8-EDNAS
|
Fluorescent Dye
|
Others
|
|
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent .
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-
- HY-D1496
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
-
- HY-D2856A
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG2000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
-
- HY-D2053
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 hydrazid is a hydrazide derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-150150F
-
-
- HY-D2773
-
|
|
Fluorescent Dye
|
Others
|
|
5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9).
Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-D2043
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 620/642 nm.
|
-
- HY-W075603
-
|
2,6-Diiodo-Pyrromethene 546
|
Fluorescent Dye
|
Others
|
|
2,6-Diiodo-BODIPY 493/503 is an F-Bodipy fluorescent dye with diiodo substitution at the (pyrrole) 2,6 position. 2,6-Diiodo-BODIPY 493/503 has a pyrrole iodine substituent that turns it red .
|
-
- HY-D2401F
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-Polystyrene microsphere (100 nm) is a Cy5 (HY-D0821)-labeled microsphere that can be used for bioimaging and drug delivery .
|
-
- HY-D0853A
-
|
H-L-Photo-lysine hydrochloride
|
Fluorescent Dye
|
Others
|
|
DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe .
|
-
- HY-D1777
-
|
PM605
|
Fluorescent Dye
|
Others
|
|
Pyrromethene 605 (PM605) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
|
-
- HY-101897
-
|
Fura-2 Acetoxymethyl ester
|
Fluorescent Dye
|
Others
|
|
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
|
-
- HY-D0219
-
|
Thymolsulphonephthalein
|
Fluorescent Dye
|
Others
|
|
Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI - form) under acidic conditions and blue (I 2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
|
-
- HY-D1065
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
|
-
- HY-W190932
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-135638
-
-
- HY-D0070
-
|
Diaminofluorescein 2T
|
Fluorescent Dye
|
Others
|
|
DAF-2T (Diaminofluorescein 2T) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W442295
-
|
|
Fluorescent Dye
|
Others
|
|
Dipyrrometheneboron difluoride is a green-fluorescent dye used for labeling nonpolar lipids and detecting calcium.
|
-
- HY-D3388
-
|
|
Fluorescent Dye
Drug Derivative
|
Others
|
|
BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
|
-
- HY-D1708
-
-
- HY-DY1033
-
|
|
Fluorescent Dye
|
Others
|
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) (solution) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di (β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-18743
-
|
|
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm) .
|
-
- HY-D2841
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Heparin is a fluorescent dye composed of FITC (HY-66019) and Heparin. FITC-Heparin can be used for cell tracing and drug delivery .
|
-
- HY-D2225
-
-
- HY-D2730
-
|
|
Bacterial
|
Infection
|
|
N14G-Fe, the Fe 3+-chelated form of N14G, identifies Mtb in sputum samples with tuberculosis, exhibiting exceptional fluorescence. N14G-Fe can effectively traverse the cell wall and inner membrane region where IrtAB is located .
|
-
- HY-D2736
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
- HY-D2603
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG10000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG10000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
-
- HY-D1687
-
|
|
Fluorescent Dye
|
Others
|
|
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .
|
-
- HY-15941
-
|
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dye
|
Others
|
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
-
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D2848A
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy5.5 (MW 55000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 55000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
-
- HY-D1482
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-D2802D
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG10000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2732
-
-
- HY-DY1007
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
|
FITC (Fluorescein Isothiocyanate) (solution) , is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-W879370
-
-
- HY-D0165
-
|
1,3-Dihydroxynaphthalene
|
Fluorescent Dye
|
Others
|
|
Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye (λex=330 nm, λem=380 nm) that can react with the NPPD (a tracer) and concentrated HCl and develop a red color. Naphthoresorcinol could be used as a background electrolyte (BGE) to determine the carbohydrates .
|
-
- HY-D2839
-
|
|
Fluorescent Dye
|
Others
|
|
m-PEG10000-PEI-Cy5 is a fluorescent dye composed of polyethylene glycol (PEG), Cy5 (HY-D0821) and Polyethyleneimine (PEI). m-PEG10000-PEI-Cy5 can be used for fluorescent labeling and imaging .
|
-
- HY-W337201
-
|
|
Fluorescent Dye
|
Others
|
|
5-Bromo-4-chloro-3-indolyl β-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases .
|
-
- HY-D2167
-
|
|
Fluorescent Dye
|
Others
|
|
AF 568 alkyne is a derivative of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Alkyne group and molecules containing Azide groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-101900R
-
|
Nile blue sulfate (Standard)
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Nile Blue A sulfate (Standard) is the analytical standard of Nile Blue A sulfate (HY-101900). This product is intended for research and analytical applications. Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
-
- HY-D2625
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA (MW 50000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
-
- HY-D1356
-
|
|
Fluorescent Dye
|
Others
|
|
Azide MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D0233
-
|
|
Fluorescent Dye
|
Others
|
|
Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials .
|
-
- HY-D2123
-
-
- HY-D1075
-
|
HIDC
|
Fluorescent Dye
|
Others
|
|
1,1',3,3,3',3'-Hexamethylindodicarbocyanine iodide is a carbocyanine dye that stains mitochondria of live cells.
|
-
- HY-D1489
-
|
|
Fluorescent Dye
|
Others
|
|
Ethyl eosin is a fluorescent dye with an absorption peak at 527 nm and an absorption shoulder at 487 nm .
|
-
- HY-118924
-
|
|
Fluorescent Dye
|
Cancer
|
|
IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal study. .
|
-
- HY-D0047
-
5-CFDA
3 Publications Verification
5-Carboxyfluorescein diacetate
|
Fluorescent Dye
|
Others
|
|
5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
-
- HY-D1916
-
|
|
Fluorescent Dye
Mucin
|
Others
|
|
ATTO 594 is a Fluorescent dye (excitation/emission = 603/626 nm). ATTO 594 is covalently conjugated to Mucin via carbodiimide coupling .
|
-
- HY-D1352A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-D2840B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-mPEG750 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG750 can be used for fluorescent labeling and imaging .
|
-
- HY-D1873
-
|
|
Fluorescent Dye
|
Others
|
|
800CW acid is an orally active near-infrared (NIR) dye (excitation/emission 774/789 nm). 800CW acid can be used for intestinal permeability testing. 800CW acid can be used for in vivo imaging studies .
|
-
- HY-118262
-
-
- HY-D2249
-
-
- HY-D1352
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-W011618
-
|
|
Fluorescent Dye
|
Others
|
|
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
|
-
- HY-P3484
-
|
|
MMP
|
Cancer
|
|
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .
|
-
- HY-D2650
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
|
-
- HY-D0815
-
|
|
Fluorescent Dye
DNA/RNA Synthesis
|
Others
|
|
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
|
-
- HY-D1386
-
|
|
Fluorescent Dye
|
Others
|
|
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .
|
-
- HY-D2360
-
|
|
HIF/HIF Prolyl-Hydroxylase
HSP
|
Cancer
|
|
O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity .
|
-
- HY-D2495
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.
|
-
- HY-D1557
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2748
-
|
|
Fluorescent Dye
|
Others
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-D2180
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D1304
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 488 azide ditriethylamine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-114958
-
|
|
Fluorescent Dye
|
Others
|
|
RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase .
|
-
- HY-163140
-
|
|
Fluorescent Dye
Interleukin Related
|
Others
|
|
BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction .
|
-
- HY-D1465
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa 532 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D1426
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Di-12-ANEPPQ is a fast-responding membrane potential dye. Di-12-ANEPPQ, the lipophilic dye, shows cell-specific loading and Golgi-like staining patterns with minimal background fluorescence in the slices of neocortex and hippocampus .
|
-
- HY-D2836J
-
|
FITC-Hyaluronate (MW 3000)
|
Fluorescent Dye
|
Others
|
|
FITC-HA (MW 3000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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-
- HY-D2136
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1594
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .
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-
- HY-126821
-
|
|
Fluorescent Dye
|
Others
|
|
Fluo-3 is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
|
-
- HY-D2077
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 azide is an azide derivative of ATTO 725 with excitation/emission maxima at 728/751 nm. ATTO 725 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D1924
-
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Fluorescent Dye
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Others
|
|
ATTO 390 alkyne is an alkyne derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm. ATTO 390 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D2711
-
|
|
Fluorescent Dye
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Others
|
|
Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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-
- HY-D2800D
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG10000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG10000-MAL can be used for fluorescent labeling and imaging .
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-
- HY-D1949
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Streptavidin is a streptavidin derivative of ATTO 594, it can label protein or antibody, the maximum excitation/emission wavelength: 603/626 nm.
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-
- HY-D2856B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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-
- HY-D2634
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
-
- HY-124409
-
WSP-1
2 Publications Verification
|
Fluorescent Dye
|
Others
|
|
WSP-1 is a selective and rapid-reaction H2S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H2S with the releasing of fluorophore .
|
-
- HY-D2421
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Cancer
|
|
DEAE-dex-Cy5 is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, Dextran (dex) and Diethylaminoethyl (DEAE). Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Dex has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
|
-
- HY-D2606
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG3400 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG3400 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
-
- HY-D2737
-
|
BHQ-2 DMT amidite
|
Fluorescent Dye
|
Others
|
|
DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
|
-
- HY-D2855
-
|
|
Fluorescent Dye
|
Others
|
|
Heparin-Cy7.5 is a fluorescent dye composed of CY7.5 (HY-D0926) and heparin. Heparin-CY7.5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 770/820 nm).
|
-
- HY-D1537
-
|
DBCO-Cy5.5; Cyanine5.5 DBCO
|
Fluorescent Dye
|
Others
|
|
Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging .
|
-
- HY-D2684
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
|
-
- HY-131029
-
|
JF646, Maleimide
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1578
-
|
|
Fluorescent Dye
β-glucuronidase
|
Others
|
|
C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .
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-
- HY-111391
-
|
Diazoresorcinol sodium
|
Bacterial
Fluorescent Dye
|
Infection
|
|
Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
|
-
- HY-D2605
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG2000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG2000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
-
- HY-D2694
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 100000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-DY1045
-
|
|
Amyloid-β
|
Neurological Disease
|
Methoxy-X04 (solution) is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity .
Solvent and concentration: DMSO: 5 mg/mL
|
-
- HY-D0162R
-
|
MCCK1 (Standard)
|
Reference Standards
Fungal
IKK
NF-κB
Apoptosis
|
Infection
Cancer
|
|
Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate (HY-D0162). This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
|
-
- HY-101888
-
-
- HY-D2268A
-
|
|
Amyloid-β
Fluorescent Dye
|
Neurological Disease
|
|
QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
-
- HY-D2428
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Infection
Inflammation/Immunology
Cancer
|
|
OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
|
-
- HY-158746
-
|
Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity
|
Fluorescent Dye
|
Others
|
|
Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration .
|
-
- HY-172717
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.
|
-
- HY-131131
-
|
|
Fluorescent Dye
|
Others
|
|
5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein, which contains an additional negative charge and can be better retained in the cell. 5-CFDA-AM can be used to detect cell viability .
|
-
- HY-D1626
-
|
3,3'-Dioctadecylthiacarbocyanine perchlorate
|
Fluorescent Dye
|
Others
|
|
DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .
|
-
- HY-D0037
-
|
|
Fluorescent Dye
|
Others
|
|
5-Bromomethyl-fluorescein is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2846B
-
|
|
Fluorescent Dye
|
Others
|
|
m-PEG5000-PEI5000-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG5000-PEI5000-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em=633/670 nm).
|
-
- HY-129887
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .
|
-
- HY-D3304
-
|
|
Fluorescent Dye
|
Others
|
|
Cholyl-L-lysine fluorescein disodium is a Fluorescent substrate. Cholyl-L-lysine fluorescein disodium can be used in organoid research .
|
-
- HY-136886
-
IR-820
2 Publications Verification
New Indocyanine Green
|
Fluorescent Dye
|
Cancer
|
|
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
|
-
- HY-113217F
-
|
|
Fluorescent Dye
Liposome
|
Metabolic Disease
|
|
BODIPY 480/508-cholesteryl oleate is a fluorescently tagged derivative of Cholesteryl oleate (HY-113217). BODIPY 480/508-cholesteryl oleate can be used to monitor lipid transport mechanisms in mammalian cells (Ex/Em = 480/508 nm) .
|
-
- HY-101893R
-
|
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Dihydrofluorescein diacetate (Standard) is the analytical standard of Dihydrofluorescein diacetate (HY-101893). This product is intended for research and analytical applications. Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
|
-
- HY-D2270
-
|
|
Fluorescent Dye
|
Others
|
|
Halo tag TMR is a red fluorescent dye composed of Halo tag ligand molecules and TMR (TAMRA). Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity (Ex/Em = 550/576 nm) .
|
-
- HY-116862
-
|
DBF
|
Cytochrome P450
Fluorescent Dye
|
Others
|
|
Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its Km value of 0.87-1.9 μM (Ex=485 nm，Em=535 nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .
|
-
- HY-D2431
-
|
|
Fluorescent Dye
|
Others
|
|
Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
|
-
- HY-D2686
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
|
-
- HY-DY1032
-
|
|
Fluorescent Dye
|
Others
|
Mito-Tracker Green (solution) is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.
Solvent and concentration: DMSO: 1 mM
|
-
- HY-D2657
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 5000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
-
- HY-D2682
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
|
-
- HY-141575
-
|
|
Fluorescent Dye
|
Others
|
|
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
|
-
- HY-W009756
-
|
|
Fluorescent Dye
|
Others
|
|
N-Phenyl-1-naphthylamine is a dye that fluoresces strongly when bound to the inner phospholipid bilayer of Gram-negative bacteria. N-Phenyl-1-naphthylamine can be used to measure outer membrane permeability. N-Phenylnaphthalen-1-amine is a fluorescence probe for odorant-binding proteins (OBP) with a dissociation constant of 1.67 μM. N-Phenylnaphthalen-1-amine exhibits an excitation wavelength of 337 nM and an emission wavelength of 407 nM .
|
-
- HY-W089353
-
|
|
MOFs
Fluorescent Dye
|
Others
|
|
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .
|
-
- HY-W190940
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG4-S-S-acid is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.
|
-
- HY-D2543
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3400-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D0103
-
|
|
Fluorescent Dye
|
|
|
Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-D2231
-
|
|
ADC Payload
|
Others
|
|
Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
|
-
- HY-D3449
-
|
|
Fluorescent Dye
Reactive Oxygen Species (ROS)
|
Others
|
|
8-(9-Bromoanthracene)-BODIPY 505/515 is a fluorescence turn-on probe with selective fluorescence turn-on response towards hydroxyl radical. 8-(9-Bromoanthracene)-BODIPY 505/515 can be used to detect reactive oxygen/nitrogen species (ROS/RNS) . (Ex/Em = 505/515 nm)
|
-
- HY-D2420
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG5-Mal is a PROTAC linker, belonging to the PEG class. It can be used for the synthesis of PROTAC molecules .
|
-
- HY-DY1101
-
|
Fura-2 Acetoxymethyl ester (solution)
|
Fluorescent Dye
|
Others
|
Fura-2 AM (solution) (Fura-2 Acetoxymethyl ester (solution)) is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
Solvent and concentration: DMSO: 1 mM
|
-
- HY-D2246
-
-
- HY-D2646
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 200000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-D1517
-
|
|
Fluorescent Dye
|
Others
|
|
FM 2-10 is a fluorescent dye. FM 2-10 is a less hydrophobic version of FM 1-43 (HY-D1434). FM 2-10 can be used for identifying actively firing neurons and investigating the mechanisms of activity-dependent vesicle cycling .
|
-
- HY-D0076
-
|
DAF-2
|
Fluorescent Dye
|
Cancer
|
|
4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues .
|
-
- HY-D2358
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
Glucosamine-CY5.5 is CY5.5-labeled Glucosamine (HY-B1125). Glucosamine-CY5.5 can be used to localize Glucosamine in living cells .
|
-
- HY-D2648
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
|
-
- HY-D1415
-
|
|
Fluorescent Dye
|
|
|
Cyanine 5 Bisfunctional MTSEA Dye potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-151711
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1896
-
|
|
Fluorescent Dye
|
Others
|
|
Chloride Ionophore IV is a thiourea type hydrogen bonding-based receptor. Chloride Ionophore IV is a chloride ionophore .
|
-
- HY-D1740
-
|
DHTM Ros
|
Fluorescent Dye
|
Others
|
|
Dihydrotetramethylrosamine (DHTM Ros) is a fluorogenic substrate for peroxidase that oxidizes to fluorescent tetramethylrosamine chloride.
|
-
- HY-D2817
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PLL is a fluorescent dye composed of poly-lysine (PLL) and FITC (HY-66019). FITC-PLL can be used for cell labeling and has nucleic acid binding ability .
|
-
- HY-D1911
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Fluorescent Dye
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Others
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ATTO 665 Biotin is a biotin derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
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- HY-D2844
-
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Fluorescent Dye
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Neurological Disease
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FITC-PEG400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG400-FA can be used for fluorescent labeling and imaging .
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- HY-D3256
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Fluorescent Dye
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Others
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AF 532 NHS ester is a fluorescent dye AF 532 derivative exhibits high fluorescence quantum yield and high photostability. AF 532 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 530/555 nm).
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- HY-D2802C
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Fluorescent Dye
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Others
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FITC-PEG5000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2836D
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FITC-Hyaluronate (MW 50000)
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Fluorescent Dye
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Others
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FITC-HA (MW 50000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D2573
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Fluorescent Dye
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Others
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Cy5.5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.
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- HY-D1872
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Fluorescent Dye
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Others
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800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
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- HY-D2836C
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FITC-Hyaluronate (MW 100000)
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Fluorescent Dye
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Others
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FITC-HA (MW 100000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D1705
-
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Proteasome
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Inflammation/Immunology
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Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .
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-
- HY-D1522
-
-
![N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine](//file.medchemexpress.com/product_pic/hy-d1522.gif)
- HY-116583
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- HY-D0074
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Fluorescent Dye
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Others
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Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent .
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- HY-D1678
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Fluorescent Dye
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Others
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5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm) .
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-
- HY-D1028
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Fluorescent Dye
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Others
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DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins (Ex/Em = 633/665 nm) .
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- HY-D1326
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Fluorescent Dye
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Others
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Cyanine3 carboxylic acid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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-
- HY-D1703
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Fluorescent Dye
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Others
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Oxazine 170 perchlorate is a laser dye with a wide excitation spectrum range (300−550 nm), which strongly absorbs light with a wavelength greater than 550 nm, and it emits fluorescence with a wavelength of about 645 nm .
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-
- HY-D1427
-
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Fluorescent Dye
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Neurological Disease
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|
Di-2-ANEPEQ is a voltage sensitive membrane potential fluorescence dye. Di-2-ANEPEQ can be used for the evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system .
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-
- HY-D1042
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Fluorescent Dye
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Others
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1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
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- HY-D3308
-
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Biochemical Assay Reagents
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Others
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CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion .
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- HY-D1851
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Fluorescent Dye
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Others
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Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-W998694
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Fluorescent Dye
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Others
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6-CR, 6G is an acceptor chromophore commonly used in energy transfer (ET) fluorescent primers .
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- HY-D1471
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Fluorescent Dye
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Others
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10-(3-Sulfopropyl)acridinium Betaine is a fluorescent dye with high durability (>3 months) .
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- HY-P3749
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Fluorescent Dye
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Others
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Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .
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-
- HY-D2226
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-
- HY-W998707
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Fluorescent Dye
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Others
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TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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-
- HY-101899
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Chlorobimane，mBBr
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Fluorescent Dye
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Others
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Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
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- HY-D2795C
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Fluorescent Dye
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Others
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FITC-PEG10000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG10000-COOH can be used for fluorescent labeling and imaging .
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- HY-D2734
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Fluorescent Dye
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Others
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Heparin-Cy3 is a fluorescent dye composed of Cy3 (HY-D0822) and Heparin. Heparin-Cy3 can be used for cell tracing and drug delivery .
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- HY-156304
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Fluorescent Dye
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Others
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Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-D2840I
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Fluorescent Dye
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Others
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FITC-mPEG20000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG20000 can be used for fluorescent labeling and imaging .
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-
- HY-101898
-
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Indo-1 Acetoxymethyl ester
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Fluorescent Dye
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Others
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Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.
MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
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-
- HY-114352
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Fluorescent Dye
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Others
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BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λex=504 nm, λem=510 nm) .
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-
- HY-113238F
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FITC-Sulfolithocholic acid
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Fluorescent Dye
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Others
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FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases .
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-
- HY-D1525
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Fluorescent Dye
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Others
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N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin .
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-
- HY-D2846A
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Fluorescent Dye
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Others
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m-PEG2000-PEI2000-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG2000-PEI2000-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em=633/670 nm).
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-
- HY-D2836A
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FITC-Hyaluronate (MW 500000)
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Fluorescent Dye
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Others
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FITC-HA (MW 500000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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-
- HY-D1313
-
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Fluorescent Dye
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Others
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PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-112624F1
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Fluorescent Dye
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Others
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CY5-Dextran (MW 4000) is a fluorescent dye CY5 (HY-D0821)-labeled Dextran (HY-112624). Dextran-CY5 (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
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-
- HY-D1307
-
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Fluorescent Dye
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Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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-
- HY-D0113
-
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Reactive Oxygen Species (ROS)
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Others
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7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .
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-
- HY-131021
-
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JF549, Azide
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Fluorescent Dye
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Others
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Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D2555
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Fluorescent Dye
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Others
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Cy5.5-PEG10000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG10000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
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-
- HY-D0075
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Fluorescent Dye
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Others
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DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .
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-
- HY-D2850
-
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Fluorescent Dye
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Others
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Heparin-Cy5.5 is a fluorescent dye composed of CY5.5 (HY-D0924) and heparin. Heparin-CY5.5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 680/710 nm).
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-
- HY-D0134
-
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Fluorescent Dye
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Others
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|
NIR-797-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2767
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Fluorescent Dye
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Others
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MB 660R NHS Ester is a fluroescent agent with a terminal NHS ester group.MB 660R NHS Ester is a far-red fluorescent dye that has a maximal absorption of 665 nm and emission at 690 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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-
- HY-D2379A
-
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Fluorescent Dye
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|
|
closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent .
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-
- HY-D2844D
-
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Fluorescent Dye
|
Neurological Disease
|
|
FITC-PEG5000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG5000-FA can be used for fluorescent labeling and imaging .
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-
- HY-D0089
-
|
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Fluorescent Dye
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Others
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|
O'-(carboxymethyl)fluoresceinamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2215
-
|
|
Fluorescent Dye
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Cancer
|
|
Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .
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-
- HY-D2102
-
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Fluorescent Dye
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Others
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|
TAMRA-PEG7-NH2 is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
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-
- HY-D1237
-
|
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Fluorescent Dye
|
Metabolic Disease
|
|
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
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-
- HY-100512
-
-
- HY-D2258
-
-
- HY-DY1004
-
|
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Fluorescent Dye
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Others
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BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm.
Solvent and concentration: DMSO: 5 mM.
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-
- HY-103373
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively) . PE154 can label β-amyloid plaques in histochemical analysis .
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-
- HY-D0139
-
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Fluorescent Dye
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Others
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|
Octadecyl Rhodamine B (perchlorate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D1972
-
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Fluorescent Dye
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Others
|
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ATTO 610 Carboxy is a carboxyl derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
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-
- HY-D2336
-
|
|
PROTACs
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Cancer
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|
PROTAC Aster-A degrader-1 (compound NGF3) is a degrader of the sterol transport protein Aster-A. PROTAC Aster-A degrader-1 can be used as a fluorescence probe. (Red: Aster-A inhibitor, black: linker, Blue: E3 ligase ligand) .
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-
- HY-D2826
-
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Fluorescent Dye
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Others
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FITC-Chitosan (MW 100000) is a chitosan (Chitosan) (HY-B2144A) labeled with FITC (HY-66019). FITC-Chitosan (MW 100000) combines the biological and physicochemical properties of chitosan (such as biocompatibility, positive charge, and nanoparticle-forming ability) with the fluorescent visibility of FITC (Ex/Em = ~485/535 nm) .
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-
- HY-W800775
-
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Fluorescent Dye
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Others
|
|
BP Fluor 647 Alkyne is a bright green-fluorescent dye optimal for use with the 633, 650 nm Argon laser. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The dye is water soluble and pH-insensitive from pH 4 to pH 10. The dye has 4 sulfonate groups which make it highly water soluble and cause less aggregation in the aqueous solution. BP Fluor 647 Alkyne is used for protein and antibody labeling, or nucleic acid applications with high labeling density.
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-
- HY-151750
-
-
- HY-D2662
-
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Fluorescent Dye
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Others
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|
Cy5.5 HA (MW 200000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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-
- HY-D1091
-
-
- HY-106594B
-
|
Pigment blue 27
|
Bacterial
|
Infection
Cancer
|
|
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
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-
- HY-155327
-
|
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Fluorescent Dye
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Others
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|
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-114289
-
6-HEX
1 Publications Verification
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Fluorescent Dye
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Others
|
|
6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group .
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-
- HY-D2493
-
|
Cy7 COOH
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Fluorescent Dye
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Others
|
|
Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds .
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-
- HY-155438
-
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Fluorescent Dye
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Others
|
|
Mal-Cz is a maltose-derived fluorescence-on imaging probe for the detection of E. coli and Staphylococcus aureus . It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-137103
-
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Fluorescent Dye
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Others
|
|
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .
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-
- HY-136784A
-
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Fluorescent Dye
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Others
|
|
Rhod-2 sodium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 sodium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
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-
- HY-D1893
-
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Fluorescent Dye
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Others
|
|
HEX azide, 6-isomer, a derivate of fluorescent dye hexachlorofluorescein (HEX), can be used for labeling oligonucleotides .
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-
- HY-D2381
-
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Fluorescent Dye
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Others
|
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AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .
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-
- HY-D2695
-
|
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Fluorescent Dye
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Others
|
|
Cy7.5 HA (MW 200000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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-
- HY-W800831
-
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Fluorescent Dye
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Others
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|
Tetra-sulfo-Cy7 DBCO is a bright and photostable near-IR probe. The Cy7 DBCO is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy7 DBCO is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.
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-
- HY-D1045
-
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DABCYL; Para-methyl red
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Fluorescent Dye
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Others
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|
Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
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-
- HY-136894
-
|
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Fluorescent Dye
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Others
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|
Rhod-5N is a cell-impermeant calcium-binding fluorescent dye composed of a BAPTA chelating group and a rhodamine fluorophore. Rhod-5N is often added to MOPS buffer to complex and indicate cation content. The selectivity of Rhod-5N for Cd 2+ is higher than other interfering cations ((Na+, K+, Mg 2+, Ca 2+, Zn 2+) except Pb 2+), and the detection limit is 3.1 μg/L .
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-
- HY-D1365
-
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Fluorescent Dye
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Others
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|
Sulfo-Cy3(Me)COOH is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .
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-
- HY-D2075
-
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Fluorescent Dye
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Others
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|
ATTO 740 streptavidin is a streptavidin derivative of ATTO 740, it can label protein or antibody, the maximum excitation/emission wavelength: 743/763 nm.
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-
- HY-155327A
-
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Fluorescent Dye
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Others
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Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-DY1002
-
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Reactive Oxygen Species (ROS)
Fluorescent Dye
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Others
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H2DCFDA (DCFH-DA) (solution) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) .
Solvent and concentration: DMSO: 10 mM.
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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-
- HY-D2159
-
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Fluorescent Dye
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Others
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|
Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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-
- HY-D2380
-
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G-quadruplex
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Cancer
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|
H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC50=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (Kd=1.72 μM). H2S probe 1 can be used in cancer research .
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-
- HY-W216621
-
|
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Fluorescent Dye
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Others
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|
Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization .
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- HY-D2027
-
|
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Fluorescent Dye
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Others
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|
ATTO 550 amine is an amine derivative of ATTO 550, the maximum excitation/emission wavelength: 554/576 nm.
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-
- HY-D0097
-
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Fluorescent Dye
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Others
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|
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label. 7-Fluorobenzofurazan-4-sulfonic acid ammonium can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH) .
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-
- HY-D2137
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-101887
-
|
|
Fluorescent Dye
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Others
|
|
Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator .
|
-
- HY-112624F4
-
-
- HY-103594
-
-
- HY-D1564
-
-
- HY-D2107
-
|
|
Fluorescent Dye
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Others
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|
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
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-
- HY-131027
-
|
JF646, Azide
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Fluorescent Dye
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Others
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|
Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D3390
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
sCy5DA is a is a fluorescent D-amino acid . sCy5DA incorporates into bacterial peptidoglycan layers and cross-links via transpeptidase action, replacing peptidoglycan stem peptide D-amino acids. sCy5DA labels live bacterial cell walls, nascent peptidoglycan biosynthesis sites, and diverse bacterial species including Gram-negative, Gram-positive, and mycobacteria (Ex/Em = 646/665 nm) .
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-
- HY-D2574
-
|
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Fluorescent Dye
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Others
|
|
Cy5.5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.
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-
- HY-D2865
-
|
|
Fluorescent Dye
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Others
|
|
Celltrack Deep Red is a fluorescent dye with a fluorescence signal that can be maintained for at least 72 h and has good stability. Celltrack Deep Red can be used for cell tracing and multi-generation cell movement tracking. Within a cell population, Celltrack Deep Red is only transferred to daughter cells and not to neighboring cells (Ex/Em = 630/650 nm) .
|
-
- HY-D1931
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 590 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 594/622 nm.
|
-
- HY-D2854
-
|
|
Fluorescent Dye
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Others
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|
FITC-PEG400-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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-
- HY-D2514
-
|
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Fluorescent Dye
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Others
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|
Cy3-PEG1000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG1000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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-
- HY-W726893
-
-
- HY-D2524
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy3 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy3 is approximately 562-570 nm.
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-
- HY-D1076
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
DiIC16(3) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
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-
- HY-D2430
-
|
|
Fluorescent Dye
Bacterial
Fungal
|
Infection
Cancer
|
|
Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, Chitosan and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi .
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-
- HY-D2032
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 514 amine is an amine derivative of ATTO 514, the maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-D1881A
-
-
- HY-D0214
-
|
|
Influenza Virus
Photosensitizer
Amyloid-β
|
Infection
Neurological Disease
Cancer
|
|
Acid Red 94 sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Acid Red 94 sodium can inhibit Aβ aggregation through light irradiation. Acid Red 94 sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research .
|
-
- HY-120649
-
|
|
Biochemical Assay Reagents
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Others
|
|
SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .
|
-
- HY-D0128
-
|
7-Methoxy-4-methylcoumarin
|
Bacterial
|
Infection
|
|
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml .
|
-
- HY-D2849
-
|
|
Fluorescent Dye
|
Others
|
|
Heparin-Cy5 is a fluorescent dye composed of CY5 (HY-D0821) and heparin. Heparin-CY5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 633/670 nm).
|
-
- HY-D1859
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1994
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D1772
-
-
- HY-D2842E
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG10000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG10000-biotin can be used for fluorescent labeling and imaging .
|
-
- HY-D2268
-
|
|
Fluorescent Dye
Amyloid-β
|
Neurological Disease
|
|
QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
-
- HY-D2595
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5-PEG5000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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-
- HY-D1961
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D0081
-
|
|
Fluorescent Dye
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Others
|
|
4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2506
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG3400-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG3400-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-111382
-
|
DTZ
|
Fluorescent Dye
|
Cancer
|
|
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios .
|
-
- HY-D2116
-
|
|
Fluorescent Dye
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Others
|
|
TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1742
-
|
|
Fluorescent Dye
DNA Stain
|
Others
|
|
DeepRed Nucleus Dye is a novel cell permeant and far red-fluorescing DNA probe. DeepRed Nucleus Dye excites at a wavelength of 647 nm, close to the Ex, and produces a fluorescence spectrum extending from 665 nm out to beyond 780 nm wavelengths. DeepRed Nucleus Dye fluorescence reflects cellular DNA content. DeepRed Nucleus Dye can be used in combination with FITC and RPE-labelled antibodies, without the need for fluorescence compensation .
|
-
- HY-DY1006
-
|
|
Fluorescent Dye
DNA/RNA Synthesis
|
Others
|
Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis.
Solvent and Concentration: Sterile water: 1 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-137834A
-
-
- HY-D1477
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Carboxyfluorescein diisobutyrate is a protected 5(6)-carboxyfluorescein. 5(6)-carboxyfluorescein is a fluorescence pH indicator .
|
-
- HY-D2703
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA biotin (MW 5000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
|
-
- HY-42984
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1669
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-114353
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments .
|
-
- HY-D1971
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-101878
-
|
Sulforhodamine 101; SR101
|
Fluorescent Dye
|
Neurological Disease
|
|
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
|
-
- HY-D1603
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL-EDA is a widely used fluorescent dye for quantitative analysis of nucleotides. BODIPY FL-EDA is an aliphatic amine analog that can react with aldehydes and ketones. BODIPY FL-EDA can be used to detect both modified and unmodified deoxynucleotides and to determine DNA damage and genomic DNA methylation through capillary electrophoresis with laser-induced fluorescence (CE-LIF). Additionally, it can be used for quantifying intracellular ATP levels. The excitation wavelength is 500 nm, and the emission wavelength is 510 nm .
|
-
- HY-123533A
-
|
NSC 12097 sodium salt
|
Reactive Oxygen Species (ROS)
|
Others
|
|
Resorufin sodium salt (NSC 12097) is a highly fluorescent pink dye. Resorufin sodium salt shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin sodium salt is used for the detection of ROS/RNS and a second analyte .
|
-
- HY-DY1077
-
|
|
Fluorescent Dye
|
Others
|
Rhodamine B (solution) is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2840C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-mPEG1000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG1000 can be used for fluorescent labeling and imaging .
|
-
- HY-D2114
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2546
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-biotin is a polyethylene glycol derivative containing Cy5 (HY-D0821) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5-PEG2000-biotin plays an important role in the specific capture and detection of biomolecules.
|
-
- HY-W094758A
-
|
|
Fluorescent Dye
|
Cancer
|
|
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λex /λem = 475/606 nm) .
|
-
- HY-D1327
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm) [1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2321
-
|
|
Fluorescent Dye
|
Others
|
|
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form .
|
-
- HY-DY1098
-
|
2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)
|
Fluorescent Dye
|
Others
|
BCECF (solution) (2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)) is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
Solvent and concentration: DMSO: 10 mM
|
-
- HY-111956
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-DY1080
-
|
Monodansyl cadaverine (solution)
|
Autophagy
|
Others
|
Dansylcadaverine (solution) (Monodansyl cadaverine (solution)) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D1431
-
|
|
Fluorescent Dye
|
Cancer
|
|
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm .
|
-
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-101894R
-
|
DHR 123 (Standard)
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Dihydrorhodamine 123 (Standard) is the analytical standard of Dihydrorhodamine 123 (HY-101894). This product is intended for research and analytical applications. Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
|
-
- HY-D0922
-
-
- HY-D1775
-
|
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
|
LysoTracker blue DND-22 is a blue fluorescent dye (Ex/Em: 373/422 nm). LysoTracker blue DND-22 stains acidic regions in living cells. LysoTracker blue DND-22 is used in the researches of neurodegenerative diseases and leukemia .
|
-
- HY-D1390
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy5-Mal potassium is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal potassium specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal potassium can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
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-
- HY-D1938
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 Biotin is a biotin derivative of ATTO 465 with maximum excitation/emission wavelengths: 453/506 nm.
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-
- HY-D1553
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used to quantify viscosity, critical micelle concentration, and critical micelle temperature .
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-
- HY-D1960
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
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-
- HY-D2046
-
|
|
Fluorescent Dye
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Others
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|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
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-
- HY-D2000
-
|
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Fluorescent Dye
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Others
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|
ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
|
-
- HY-P1986
-
|
|
Caspase
|
Cancer
|
|
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
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-
- HY-162075
-
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Biochemical Assay Reagents
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Others
|
|
RF16 is a fluorescent macromolecular material. RF16 precisely retains in cells to track IRE1-Halo protein with the HaloTag ligand .
|
-
- HY-100575
-
|
Acriflavinium chloride 3,6-Acridinediamine mix
|
Environmental Pollutants
Fluorescent Dye
Monocarboxylate Transporter
Bacterial
Fungal
HIF/HIF Prolyl-Hydroxylase
SARS-CoV
|
Infection
Cancer
|
|
Acriflavine (Acriflavinium chloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine is an antiseptic agent. Acriflavine is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2 .
|
-
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dye
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Others
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).
|
-
- HY-124171
-
|
|
Fluorescent Dye
Drug Derivative
|
Others
|
|
Zinquin ethyl ester is a cell-permeable and lipophilic fluorescent derivative of Zinquin (HY-D0982). Zinquin ethyl ester reacts with protein-bound Zn 2+ in cells and forms fluorescent ternary adducts. Zinquin ethyl ester undergoes hydrolysis by intracellular esterases impeding its efflux across the plasma membrane (Ex/Em = 370/470 nm) .
|
-
- HY-D1335
-
|
|
Fluorescent Dye
|
|
|
TAMRA amine, 5-isomer is an isomer of TAMRA, a xanthene dye with orange emission.
|
-
- HY-D2252
-
-
- HY-D2759
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
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-
- HY-D2193
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
-
- HY-D0825
-
|
Sulfo-Cyanine7
|
Fluorescent Dye
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Others
|
|
CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-W848699
-
|
|
Fluorescent Dye
|
Others
|
|
FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
|
-
- HY-W098721
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Z-Gly-Sar-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-D1092
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye .
|
-
- HY-D2120A
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D1693
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
FBBBE is used to detect the production of H2O2 by cells. FBBBE can be triggered by intracellular H2O2 and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm) .
|
-
- HY-101879R
-
|
|
DNA Stain
Reference Standards
Parasite
Fluorescent Dye
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Others
|
|
Acridine Orange hydrochloride (Standard) is the analytical standard of Acridine Orange hydrochloride (HY-101879). This product is intended for research and analytical applications. Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
|
-
- HY-D1086
-
|
6-ROX, SE
|
DNA Stain
|
Others
|
|
6-Carboxy-X-rhodamine, succinimidyl ester (6-ROX, SE) is a fluorescent dye for oligonucleotide labeling and automated DNA sequencing .
|
-
- HY-D2292
-
|
|
Fluorescent Dye
|
Cancer
|
|
BODIPY TMR acid is a fluorescent dye. BODIPY TMR acid is a high quantum yield fluorophore which can be coupled with Rebastinib .
|
-
- HY-D1976
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D1773
-
|
|
Fluorescent Dye
DNA Alkylator/Crosslinker
|
Others
|
|
YOYO-3 is a trimethine cyanine homodimer dye. YOYO-3 intercalates into AF488-tagged dsDNA molecules at the single-molecule level. YOYO-3 has a greater affinity for DNA than do EB and other Cyanine dyes .
|
-
- HY-D1388
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2765
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
|
-
- HY-W800680
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-D2183
-
|
|
Fluorescent Dye
|
Others
|
|
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .
|
-
- HY-DY1069
-
|
|
Fluorescent Dye
|
Others
|
Cy3 NHS ester (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-126172
-
|
|
Fluorescent Dye
|
Cancer
|
|
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .
|
-
- HY-173308
-
|
|
Fluorescent Dye
|
Others
|
|
QSY-21 is a fluorescence quencher. QSY-21 possesses broad absorption in far red and NIR range, and can quench fluorescence of dyes that emit in this region. This is a carboxylic acid derivative. QSY-21 has intense absorption maximum at 661 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications. It is a common quencher for Cyanine5, Cyanine5.5, AF 647, or other spectrally similar fluorescent dyes.
|
-
- HY-D2178
-
|
|
Fluorescent Dye
|
Others
|
|
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
|
-
- HY-DY1088
-
|
N-(5-Fluoresceinyl)maleimide (solution)
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-N2306R
-
|
Aclarubicin (Standard)
|
Reference Standards
Topoisomerase
DNA/RNA Synthesis
Proteasome
Antibiotic
|
Cancer
|
|
Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
|
-
- HY-D2621
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA (MW 5000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
-
- HY-D1691
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester can be used for the labeling of amine containing biomolecules .
|
-
- HY-D2149
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D3387
-
|
|
Fluorescent Dye
|
Others
|
|
TBI is a fluorescence enhancer with a Kd of 71 nM for the Broccoli fluorogenic RNA aptamer. TBI binds to the Broccoli fluorogenic RNA aptamer to activate its fluorescence.TBI undergoes photobleaching of its trans form, which dissociates rapidly, while cis-TBI from the media replaces the dissociated fluorophore to enable fluorophore recycling.TBI enables enhanced fluorescence of Broccoli during continuous cellular imaging (Ex/Em = 485/527 nm) .
|
-
- HY-D2162
-
|
|
Fluorescent Dye
|
Others
|
|
AF 594 carboxylic acid is a carboxyl derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 carboxylic acid can form stable covalent bonds through the reaction of carboxylic acid groups with molecules with amino groups .
|
-
- HY-D2858B
-
|
|
Fluorescent Dye
|
Others
|
|
8-arm-PEG40000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG40000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
-
- HY-117070
-
|
|
Fluorescent Dye
|
Others
|
|
TO-PRO-3 iodide is a cell-impermeant nucleic acid stain. TO-PRO-3 iodide is useful as a nuclear counterstain and dead cell indicator (Ex/Em = 642/661 nm).
|
-
- HY-138200
-
|
Cyanine5 maleimide
|
DNA Stain
Fluorescent Dye
|
Others
|
|
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).
|
-
- HY-D1541
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
|
-
- HY-D2172
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 carboxylic acid is a non-reactive AF 488 form. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-110251A
-
|
|
DNA Stain
|
Others
|
|
DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells .
|
-
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2804
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7 (MW 10000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 10000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2401F1
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-Polystyrene microsphere (20um) is a Cy5 (HY-D0821)-labeled microsphere that can be used for bioimaging and drug delivery .
|
-
- HY-D1771
-
-
- HY-138659
-
|
JF646, Tetrazine
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1573
-
|
|
Fluorescent Dye
|
Others
|
|
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .
|
-
- HY-D2843
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-FITC is a fluorescent dye composed of two FITC (HY-66019) molecules and one PEG. FITC-PEG-FITC is connected to each end of the two FITC (HY-66019) molecules to form a dual-labeling structure, which is suitable for high-sensitivity fluorescence detection and imaging (Ex/Em=488/525 nm) .
|
-
- HY-D1978
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 Biotin is a biotin derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D0925
-
|
Cyanine5.5 NHS ester
|
Biochemical Assay Reagents
|
Others
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-135413
-
-
- HY-D2666
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
-
- HY-D2061
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 carboxy is a carboxyl derivative of ATTO 740, the maximum excitation/emission wavelength is: 743/763 nm.
|
-
- HY-D0156
-
|
|
Fluorescent Dye
|
Others
|
|
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .
|
-
- HY-D1421
-
|
|
Fluorescent Dye
|
Others
|
|
PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo .
|
-
- HY-W013275
-
-
- HY-D2689
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 3000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-D1514
-
-
- HY-D1680
-
|
|
Fluorescent Dye
|
Others
|
|
LysoSR-549 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2445
-
|
|
Fluorescent Dye
|
Others
|
|
AF405 acid is a fluorescent dye. AF405 exhibits a maximal excitation wavelength of 395 nm, and a maximal emission wavelength of 435 nm. AF405 is used for cell labeling and imaging .
|
-
- HY-D1373
-
HBC
3 Publications Verification
HBC 530
|
Fluorescent Dye
|
Others
|
|
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
|
-
- HY-138760
-
|
|
Fluorescent Dye
|
Others
|
|
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells .
|
-
- HY-D0219A
-
|
|
Fluorescent Dye
|
Others
|
|
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .
|
-
- HY-D1918
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D2550
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
- HY-D2539
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG5000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2532
-
|
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Fluorescent Dye
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Others
|
|
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-DY2001
-
|
|
Fluorescent Dye
Influenza Virus
Bacterial
|
Infection
|
Crystal Violet (solution) , also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining .
Solvent and Concentration: Sterile water: 5 mg/mL (0.5%)
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-
- HY-D2600
-
|
|
Fluorescent Dye
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Others
|
|
ICG PEG2000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG2000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
-
- HY-D2190
-
-
- HY-D0971
-
|
Pyronine G; C.I. 45005
|
DNA Stain
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Others
|
|
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .
|
-
- HY-D1566
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D0021
-
|
EtBr; Homidium bromide
|
DNA Stain
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Others
|
|
EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
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-
- HY-D2560
-
|
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Fluorescent Dye
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Others
|
|
Cy5.5-PEG2000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2636
-
|
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Fluorescent Dye
|
Others
|
|
Cy3 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
|
-
- HY-D2794C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG10000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG10000-NH2 can be used for fluorescent labeling and imaging .
|
-
- HY-D2846
-
|
|
Fluorescent Dye
|
Others
|
|
m-PEG-PEI800-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG-PEI8800-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em = 633/670 nm).
|
-
- HY-D2197
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-COOH (1120 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
-
- HY-D1741
-
|
3,3'-Dihexadecyloxacarbocyanine
|
Fluorescent Dye
|
Others
|
|
DiOC16(3) (3,3'-Dihexadecyloxacarbocyanine) is a lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and studies of membrane fluidity.
|
-
- HY-D2840H
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-mPEG10000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG10000 can be used for fluorescent labeling and imaging .
|
-
- HY-D3058
-
-
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dye
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Others
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D2590
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-N3 is a CY7.5 (HY-D0926)-azide fluorescent dye used to label for protein and nucleic acid. Cy7.5 PEG-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 770/820 nm).
|
-
- HY-D1895A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
3,5-DiBr-PAESA sodium is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA sodium enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .
|
-
- HY-D1432
-
|
|
Fluorescent Dye
|
Cancer
|
|
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor .
|
-
- HY-D2171
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
-
- HY-151713
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
|
-
- HY-D2110
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D0079
-
|
Hydroethidine; PD-MY 003
|
Fluorescent Dye
|
Others
|
|
Dihydroethidium, also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
|
-
- HY-D1982
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-121030
-
|
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
|
Fluorescent Dye
|
Others
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
|
-
- HY-D2836I
-
|
FITC-Hyaluronate (MW 5000)
|
Fluorescent Dye
|
Others
|
|
FITC-HA (MW 5000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
-
- HY-D2544
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D1402
-
|
|
Fluorescent Dye
|
Others
|
|
5MP-Fluorescein (compound 3e) is a fluorescein dye base on 5-Methylene pyrrolone (5MP).5-Methylene pyrrolones are highly thiol-specific and tracelessly removable bioconjugation tools .
|
-
- HY-D1516
-
|
|
Fluorescent Dye
|
Others
|
|
NerveGreen C3 is a cationic styrene based fluorescent dye. NerveGreen C3 can be used to track synaptic activity at neuromuscular junctions or synapses .
|
-
- HY-D1964
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 Biotin is a biotin derivative of ATTO 633 with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-DY1092
-
|
Ce6 (solution)
|
Caspase
Apoptosis
Fluorescent Dye
PARP
Bcl-2 Family
|
Cancer
|
Chlorin e6 (solution) (Ce6 (solution)) is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D2245
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 phosphoramidite, a cyanine derivative, is a fluorescent labeling reagent for preparing fluorescence-labeled oligonucleotides .
|
-
- HY-D2579
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo DBCO-UBQ-2 is a click chemistry reagent combining a dark quencher, UBQ-2, with a polyaromatic-azo backbone, offering no native emission. UBQ-2 effectively quenches fluorescence in the 560-670 nm range, ideal for qPCR probes and FRET applications with orange to far-red dyes .
|
-
- HY-D0011A
-
|
|
Fluorescent Dye
|
Others
|
|
Bromophenol red (sultone form) is a chemical indicator. Bromophenol red (sultone form) binds to lysozyme and inhibits its activity against the bacterial cell wall, but not the polysaccharide component of peptidoglycan .
|
-
- HY-W351340
-
|
|
Fluorescent Dye
|
Others
|
|
4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .
|
-
- HY-D2148
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-W248118
-
|
PM556
|
Fluorescent Dye
|
Others
|
|
Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
|
-
- HY-D0934
-
|
|
Fluorescent Dye
|
Others
|
|
(5)6-Carboxytetramethylrhodamine contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm .
|
-
- HY-D1297
-
|
|
Fluorescent Dye
|
Others
|
|
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation .
|
-
- HY-D1299
-
|
CF3-substituted Tetramethyl BODIPY
|
Fluorescent Dye
|
Cancer
|
|
meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy .
|
-
- HY-D1098A
-
|
|
Fluorescent Dye
|
Others
|
|
SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .
|
-
- HY-D2702
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA biotin (MW 3000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
|
-
- HY-DY1081
-
|
4',6-Diamidino-2-phenylindole dihydrochloride (solution)
|
Sodium Channel
DNA Stain
|
Neurological Disease
|
DAPI (4',6-Diamidino-2-phenylindole) dihydrochloride (solution) is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
Solvent and concentration: ddH2O: 5 mg/mL
|
-
- HY-D1349
-
|
|
Fluorescent Dye
|
|
|
Bodipy TR alkyneis one of a boron dipyrromethene fluorophore for the ROX (Texas Red) channel. This is a versatile fluorophore that can be used in microscopy, fluorescence polarization measurements, and other applications. This derivative is a terminal alkyne of copper-catalyzed click chemistry.
|
-
- HY-D2844B
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
FITC-PEG2000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG2000-FA can be used for fluorescent labeling and imaging .
|
-
- HY-D2348
-
|
|
Fluorescent Dye
|
Infection
Others
|
|
ACE is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .
|
-
- HY-D2824
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7.5 (MW 10000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 10000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2033
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 azide is an azide derivative of ATTO 514 with excitation/emission maxima at 511/531 nm. ATTO 514 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2826B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-Chitosan (MW 20000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 20000) can be used for fluorescent labeling and imaging .
|
-
- HY-Y0016
-
|
Basic Violet 10; Brilliant Pink B; Rhodamine O; Tetraethylrhodamine
|
Environmental Pollutants
Fluorescent Dye
|
Others
|
|
Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
|
-
- HY-P2208
-
|
|
Fluorescent Dye
|
Cancer
|
|
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
|
-
- HY-D2641
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 7000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-D1599
-
|
R6GH
|
Fluorescent Dye
|
Others
|
|
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
|
-
- HY-172666F
-
|
Biotin ceramide (d18:0/6:0)
|
Fluorescent Dye
|
Neurological Disease
|
|
C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
|
-
- HY-D2760A
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D1367
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
|
-
- HY-D2378
-
-
- HY-D2853
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG2000-PBA is a fluorescent dye composed of FITC (HY-66019), PEG and phenylboronic acid (PBA). FITC-PEG2000-PBA can be used for cell imaging and tracking, as well as sugar molecule detection (Ex/Em=488/525 nm).
|
-
- HY-15922A
-
|
|
Fluorescent Dye
|
Others
|
|
Luminol sodium salt is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol sodium salt exhibits chemiluminescence (CL) at 425 nm λmax. Luminol sodium salt is commonly used in forensics as a diagnostic tool for the detection of blood stains .
|
-
- HY-D2659
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 10000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
-
- HY-D2492
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-COOH is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D0212
-
|
|
Fluorescent Dye
|
|
|
Solvent blue 97 is a blue dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials.
|
-
- HY-D2570
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG5000-Biotin is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5.5-PEG5000-Biotin plays an important role in the specific capture and detection of biomolecules.
|
-
- HY-D1919
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
|
-
- HY-D1301
-
|
|
Fluorescent Dye
Ferroptosis
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
BODIPY 581/591 C11 is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .
|
-
- HY-101899R
-
|
Chlorobimane，mBBr (Standard)
|
Fluorescent Dye
Reference Standards
|
Others
|
|
Monochlorobimane (Standard) is the analytical standard of Monochlorobimane (HY-101899). This product is intended for research and analytical applications. Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
|
-
- HY-D2794
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG400-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG400-NH2 can be used for fluorescent labeling and imaging .
|
-
- HY-D1865
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-175142
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Prostaglandin E2-PEG11-biotin is a ligand. Prostaglandin E2-PEG11-biotin can be immobilized on flow cells. The immobilized Prostaglandin E2-PEG11-biotin binds to BtOCT1. Prostaglandin E2-PEG11-biotin can be used in SPR .
|
-
- HY-D2388A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
|
-
- HY-D2795A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG1000-COOH can be used for fluorescent labeling and imaging .
|
-
- HY-D2318
-
|
|
Fluorescent Dye
|
Others
|
|
Flipper-TR 5 is a Flipper probe containing a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 selectively labels the cytoplasmic membrane, and exhibits excellent mechanical sensitivity, negligible cytotoxicity and controllable phototoxicity .
|
-
- HY-D2513
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG10000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG10000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
|
-
- HY-D1555
-
|
Cy7 DBCO
|
Fluorescent Dye
|
Others
|
|
Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
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-
- HY-D2122
-
|
|
Fluorescent Dye
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Others
|
|
Cy3-PEG2-SCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-SCO carries a SCO group that can be covalently bound to an amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
-
- HY-D2160
-
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|
Fluorescent Dye
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Others
|
|
AF 647 carboxylic acid is a derivative of the far-infrared dye AF 647. AF 647 is often used as a replacement for Cy5 dye, with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). The maximum excitation wavelength is 647 nm and the maximum emission wavelength is 671 nm. AF 647 carboxylic acid has a carboxylic acid group and can be coupled to biomolecules with amino groups to achieve dye labeling .
|
-
- HY-D1884
-
|
|
Phosphoramidites
|
|
|
6-FAM-DMT-PA is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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-
- HY-D2564
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG1000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2568
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG10000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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-
- HY-D2637
-
|
|
Fluorescent Dye
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Others
|
|
Cy3 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
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-
- HY-D2554
-
|
|
Fluorescent Dye
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Others
|
|
Cy5.5-PEG5000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG5000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
-
- HY-D2422B
-
|
|
Fluorescent Dye
Microtubule/Tubulin
|
Cancer
|
|
Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
|
-
- HY-D2731
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-NO2 is a cyanine-based probe. Cy3-NO2 can be excited by using a 554 nm laser and filtered with a 568 nm laser .
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-
- HY-D1725
-
|
|
Fluorescent Dye
DNA Stain
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Others
|
|
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .
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-
- HY-D1535
-
|
|
Fluorescent Dye
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Others
|
|
IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
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-
- HY-D2065
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 biotin is a biotin derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
-
- HY-D0456
-
|
|
Fluorescent Dye
|
Others
|
|
C.I. Direct violet 66 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D1613
-
-
- HY-D2658
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA (MW 7000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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-
- HY-D2070
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 680 cadaverin is a cadaverine derivative of ATTO 680, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 681/698 nm.
|
-
- HY-D2624
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA (MW 10000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
-
- HY-131498
-
|
Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
|
Fluorescent Dye
MMP
|
Cancer
|
MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
|
-
- HY-151701A
-
|
|
Fluorescent Dye
|
Others
|
|
DiSulfo-Cy5 alkyne TEA is a fluorescent dye can be used as a click chemistry reagent .
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-
- HY-118562
-
|
|
Fluorescent Dye
|
Others
|
|
Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group (Ex/Em: 360 nm/465 nm) .
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-
- HY-145499
-
|
|
Fluorescent Dye
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Others
|
|
XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.
|
-
- HY-W277900
-
|
|
MMP
|
Inflammation/Immunology
Cancer
|
|
2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography .
|
-
- HY-137100
-
|
Cyanine5 hydrazide
|
Fluorescent Dye
|
Others
|
|
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .
|
-
- HY-D2440
-
|
|
Fluorescent Dye
|
Others
|
|
cRGD-PEG-Cy3 is a Cy3 (HY-D0822) labeled cRGD-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. cRGD can be used to modify lipid for improved stability .
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-
- HY-D2664
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
-
- HY-D2156
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 azide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 azide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the azide group and molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D2357
-
-
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
Fluorescent Dye
|
Others
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
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-
- HY-D1372A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-D1500
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
|
-
- HY-D1928
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D2602
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG5000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG5000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
-
- HY-D1904
-
|
|
Fluorescent Dye
|
Others
|
|
D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates .
|
-
- HY-D2874
-
|
|
Fluorescent Dye
|
Others
|
|
6-AF488 tyramide is a bright, green fluorescent dye (Ex=496 nm, Em=524 nm). 6-AF488 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .
|
-
- HY-D2243
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
-
- HY-D0110B
-
|
|
Fluorescent Dye
|
Others
|
|
Fura-2 pentasodium is a cell-impermeable scaled fluorescent dye that can be used for intracellular calcium imaging. Fura-2 pentasodium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca 2+ level .
|
-
- HY-D1869
-
|
|
Fluorescent Dye
|
Others
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-137023
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7 amine is a cyanine containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.
|
-
- HY-D0104
-
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D2797
-
|
|
Fluorescent Dye
|
Others
|
|
Chitosan-Cy7 (MW 2000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 2000) can be used for fluorescent labeling and imaging .
|
-
- HY-D1776
-
|
|
Fluorescent Dye
|
Others
|
|
FFP-18-AM is a cell-permeable fluorescent indicator for measurement of near-membrane calcium.
|
-
- HY-D0395
-
|
|
Fluorescent Dye
|
Others
|
|
C.I. Mordant Orange 29 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2801C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG5000-NHS can be used for fluorescent labeling and imaging .
|
-
- HY-D1977
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 Streptavidin is a streptavidin derivative of ATTO 610, it can label protein or antibody, the maximum excitation/emission wavelength: 616/633 nm.
|
-
- HY-D1672
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
TMR Biocytin is a polar tracer used in the research of cell-cell and cell-liposome fusions, as well as membrane permeability and cellular uptake during pinocytosis. TMR Biocytin can be detected using streptavidin, and is an effective neuronal tracer in live tissue (Ex=544 nm, Em=571 nm) .
|
-
- HY-D1720
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Cy5-dATP is a Cy5?(HY-D0821)-labeled dATP?(HY-136648). Cy5-dATP can be incorporated into a DNA primer .
|
-
- HY-D2052
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 iodacetamid is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 iodacetamid is an iodoacetamide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D1584
-
|
|
Phospholipase
|
Others
|
|
C12 NBD sphingomyelin is an active derivative of Sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .
|
-
- HY-D2668
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
-
- HY-D2551
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
|
-
- HY-D1624
-
|
|
Fluorescent Dye
|
Others
|
|
3,3′-Diheptylthiacarbocyanine iodide is a cyanine dye for measuring membrane potential. (λex=562 nm，λem=575 nm) .
|
-
- HY-109116
-
|
Leukomethylene blue
|
Biochemical Assay Reagents
|
Others
|
|
Hydromethylthionine (Leukomethylene blue) has a very active photochemically active reagent, especially in its interaction with dissolved oxygen. The photochemical activity of Hydromethylthionine is mainly regulated by the reaction of its triplet state with dissolved oxygen, which reacts with dissolved oxygen to form Methylene Blue (HY-14536) and hydronium ions under ultraviolet light. Hydromethylthionine can be used for the photodegradation of model pollutants in semiconductor photocatalysis and for the study of indicators in chemical analysis .
|
-
- HY-D1110
-
|
|
Fluorescent Dye
|
Others
|
|
TFAX 594,SE is a red fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 594,SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
-
- HY-122878
-
|
|
HSP
|
Cancer
|
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers .
|
-
- HY-D0060
-
|
|
Fluorescent Dye
|
Others
|
|
4-Di-2-ASP, a styryl pyridinium fluorescent dye, is a vital mitochondrial marker. 4-Di-2-ASP shows reliable and specific labelling of pulmonary NEBs (neuroepithelial bodies) .
|
-
- HY-D1498
-
|
|
Fluorescent Dye
|
Others
|
|
Mag-Fluo-4 AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Mag-Fluo-4 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
-
- HY-DY1083
-
|
|
Fluorescent Dye
|
Others
|
Zinquin (solution) is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
Solvent and concentration: DMSO: 5 mM
|
-
- HY-D1974
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
|
-
- HY-N6716
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
|
-
- HY-D2422C
-
|
|
Fluorescent Dye
Microtubule/Tubulin
Autophagy
|
Cancer
|
|
Cy5-Paclitaxel bromide is the bromide of Cy5-Paclitaxel (HY-D2422B). Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
|
-
- HY-D1569
-
|
|
Fluorescent Dye
|
Others
|
|
CellTracker Orange CMRA Dye is a fluorescent dye. CellTracker Orange CMRA Dye can be used for cell imaging and monitoring the movement and location of cells .
|
-
- HY-135415A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-15922
-
Luminol
2 Publications Verification
Diogenes reagent
|
Fluorescent Dye
|
Others
|
|
Luminol is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λmax. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains .
|
-
- HY-D0142
-
|
|
Environmental Pollutants
Fluorescent Dye
|
Others
|
|
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO2 release .
|
-
- HY-P3475
-
|
|
Fluorescent Dye
|
Others
|
|
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
|
-
- HY-D1340
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-D1375A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
|
-
- HY-D2049
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 biotin is a biotin derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
-
- HY-D2631
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
-
- HY-D0147
-
|
Pentoxyresorufin
|
Bacterial
|
Infection
|
|
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae .
|
-
- HY-P1004A
-
|
|
Fluorescent Dye
|
Others
|
|
Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B) .
|
-
- HY-D2009
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 iodacetamid is an iodoacetamide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
-
- HY-D1111
-
|
AFDye 568 NHS Ester
|
Fluorescent Dye
|
Others
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
-
- HY-D2747
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
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- HY-D2001
-
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Fluorescent Dye
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Others
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ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
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-
- HY-D1074
-
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3,3'-Dipropyloxacarbocyanine iodide
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Fluorescent Dye
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Others
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DiOC3(3) (3,3'-Dipropyloxacarbocyanine iodide) is a green fluorescent lipophilic dye with cell membrane permeability. DiOC3(3) can be used to stain cell membranes and other lipid-soluble biological structures .
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-
- HY-D2743
-
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Fluorescent Dye
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Others
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ROX alkyne, 6-isomer is an alkyne derivative of the bright red-emitting dye ROX (Rhodamine X, Rhodamine 101). Due to its quantum yield approaching unity, ROX is a popular dye for qPCR and microscopy applications. It is used for fluorescent labeling of azide-containing biomolecules via copper-catalyzed click reaction.
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-
- HY-D2113
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Fluorescent Dye
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Others
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TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D2847
-
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Fluorescent Dye
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Others
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FITC-PEG2000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
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- HY-D1462
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Fluorescent Dye
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Others
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CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
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- HY-D0925B
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Cyanine5.5 NHS ester TEA
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Fluorescent Dye
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Others
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|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
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- HY-Y0016R
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Basic Violet 10 (Standard); Brilliant Pink B (Standard); Rhodamine O (Standard); Tetraethylrhodamine (Standard)
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Fluorescent Dye
Reference Standards
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Others
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Rhodamine B (Standard) is the analytical standard of Rhodamine B. This product is intended for research and analytical applications. Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
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- HY-W588722
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Fluorescent Dye
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Others
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ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
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- HY-D2690
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Fluorescent Dye
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Others
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Cy7.5 HA (MW 5000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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-
- HY-D2638
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Fluorescent Dye
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Others
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|
Cy5 HA (MW 3000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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-
- HY-P2065
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Fluorescent Dye
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Others
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Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
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-
- HY-D0084
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DiOC6(3) iodide
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Fluorescent Dye
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Others
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3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine dye which can be used to monitor changes in mitochondrial membrane potential.
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-
- HY-D2325
-
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Fluorescent Dye
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Others
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|
Arg-Flipper 34 is one of the flipper probes which have been introduced as small molecule fluorophores to image membrane tension in living systems. Arg-Flipper 34 can be used to assess the mechanics of early endocytosis .
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-
- HY-D2837
-
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Fluorescent Dye
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Others
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|
mPEG-PEI-Cy5 (MW 2000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 2000) can be used for fluorescent labeling and imaging .
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-
- HY-D2842B
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Fluorescent Dye
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Others
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FITC-PEG2000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG2000-biotin can be used for fluorescent labeling and imaging .
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-
- HY-D1069
-
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DBCO-Sulfo-Cy3
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Fluorescent Dye
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Others
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|
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-D1738
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4',6-Diamidino-2-phenylindole dilactate
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Fluorescent Dye
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Others
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DAPI (4',6-Diamidino-2-phenylindole) dilactate is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. DAPI cannot penetrate intact cell membranes and is commonly used for staining both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm) .
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- HY-D2500
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Fluorescent Dye
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Others
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CY7 DBCO chloride is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. CY7 DBCO chloride is a click chemistry reagent. CY7 DBCO chloride contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-D2153
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Fluorescent Dye
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Others
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Cy5-PEG2-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2124
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Fluorescent Dye
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Others
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Cy3-PEG7-SCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2013
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Fluorescent Dye
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Others
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ATTO 488 hydrazid is a hydrazide derivative of ATTO 488 with excitation/emission maxima at 500/520 nm.
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-
- HY-D1848A
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Fluorescent Dye
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Others
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Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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-
- HY-D1560
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Fluorescent Dye
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Others
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FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .
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-
- HY-136784
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Fluorescent Dye
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Others
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Rhod-2 potassium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 potassium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
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-
- HY-D0972
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Thioflavin S; Direct Yellow 7
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Fluorescent Dye
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Others
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|
Thioflavine S is a fluorescent histochemical marker of dense core senile plaques. Thioflavine S can be used for Alzheimer's research .
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- HY-D0025
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Fluorescent Dye
Drug Intermediate
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Others
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7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
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- HY-D1942
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Fluorescent Dye
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Others
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ATTO 590 Biotin is a biotin derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
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-
- HY-D1512
-
-
- HY-P2536
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-
- HY-W800808
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Fluorescent Dye
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Others
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ROX azide, 5-isomer is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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-
- HY-66019
-
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Fluorescein 5-isothiocyanate
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Fluorescent Dye
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Inflammation/Immunology
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|
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
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-
- HY-D1696
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Fluorescent Dye
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Others
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|
MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm) .
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- HY-D2676
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Fluorescent Dye
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Others
|
|
Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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-
- HY-D0924A
-
|
Sulfo-Cyanine5.5 acetate
|
Fluorescent Dye
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Cy5.5 acetate is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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-
- HY-114907
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|
Eosinic acid; Solvent Red 72
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Fluorescent Dye
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Others
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4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis .
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- HY-D1945
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Fluorescent Dye
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Others
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|
ATTO 590 Iodacetamid is an iodoacetamide derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
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-
- HY-141085
-
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|
PROTAC Linkers
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Cancer
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|
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-D2844A
-
|
|
Fluorescent Dye
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Neurological Disease
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|
FITC-PEG1000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG1000-FA can be used for fluorescent labeling and imaging .
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-
- HY-D1359
-
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Fluorescent Dye
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Others
|
|
Mito Red is a vital dye and mitochondrial stain that can be used to detect and evaluate mitochondrial function and status. Mito Red accumulates in mitochondria, and its fluorescence intensity is positively correlated with mitochondrial membrane potential. When the mitochondrial membrane potential increases, the fluorescence signal of Mito Red increases .
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- HY-D1648
-
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Fluorescent Dye
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Others
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|
8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λabs=502 nm, λem=516 nm) (*abs: main absorption maxima) .
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-
- HY-115692
-
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Fluorescent Dye
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Others
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|
2-Coumaranone-1-L serves as a chemiluminescent probe. Under alkaline conditions and in the presence of oxygen, 2-Coumaranone-1-L is capable of undergoing chemiluminescence, which enables its application as a chemiluminescent substrate in biochemical assays. 2-Coumaranone-1-L exhibits its maximum emission wavelength at 442 nm. 2-Coumaranone-1-L is utilized in research within the realm of bioanalysis .
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-
- HY-DY1095
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|
Fluo-3-pentaacetoxymethyl ester (solution)
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Fluorescent Dye
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Others
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Fluo-3AM (solution) is a fluorecent Ca 2+ chelator, with high affinity for calcium. Fluo-3 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
Solvent and concentration: DMSO: 5 mM
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-
- HY-120317
-
|
|
Histone Acetyltransferase
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Others
|
|
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .
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-
- HY-P3236
-
|
Ac-IEPD-pNA
|
Ser/Thr Protease
|
Cancer
|
|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
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-
- HY-D2448
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
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-
- HY-D2042
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 610 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 616/633 nm.
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-
- HY-D1935
-
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Fluorescent Dye
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Others
|
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
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-
- HY-136248
-
|
Tyramide-Cy3
|
DNA Stain
Fluorescent Dye
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Others
|
|
Cyanine 3 Tyramide (Tyramide-Cy3) is an orange fluorescent dye used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, which serves as a signal amplification technique in immunoassays and in situ nucleic acid hybridization .
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-
- HY-D2239
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
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-
- HY-D0130
-
|
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Fluorescent Dye
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Others
|
|
Xanthamide 8 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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-
- HY-D2072
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 680 carboxy is a carboxyl derivative of ATTO 680, the maximum excitation/emission wavelength is: 681/698 nm.
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-
- HY-D0817
-
|
Rhodamine 110 chloride; RH110
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Fluorescent Dye
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Others
|
|
Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm .
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-
- HY-D1073
-
|
3,3'-Diheptyloxacarbocyanine iodide
|
Fluorescent Dye
|
Cardiovascular Disease
|
|
DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities .
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-
- HY-D2836H
-
|
FITC-Hyaluronate (MW 7000)
|
Fluorescent Dye
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Others
|
|
FITC-HA (MW 7000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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-
- HY-D1946
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 590 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 alkyne is an alkyne derivative of ATTO 590 and can be used to label proteins or antibodies.
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-
- HY-W271064
-
|
|
Environmental Pollutants
Fluorescent Dye
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Others
|
|
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
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-
- HY-147170
-
|
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Fluorescent Dye
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Others
|
|
(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes .
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-
- HY-D2836
-
|
FITC-Hyaluronate (MW 1000000)
|
Fluorescent Dye
|
Others
|
|
FITC-HA (MW 1000000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
-
- HY-101937
-
|
|
Fluorescent Dye
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Others
|
|
L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa) .
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-
- HY-D1429
-
|
|
Fluorescent Dye
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Others
|
|
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence (Ex/Em = 374/ 430-640 nm) .
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-
- HY-D1944
-
|
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Fluorescent Dye
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Others
|
|
ATTO 590 Azide is an azide derivative of ATTO 590 with excitation/emission maxima at 594/622 nm. ATTO 590 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D1190
-
|
|
RAR/RXR
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Others
|
|
DC271 is a RAR agonist and synthetic retinoid that binds to the retinoid-binding site of cellular retinoic acid-binding protein II (CRBP-II). DC271 exhibits solvatochromic fluorescence properties: it produces intense blue-shifted emission in nonpolar environments and weak red-shifted emission in polar environments, and its severe fluorescence quenching in aqueous solutions can be reversed by embedding in the hydrophobic retinoid-binding protein pocket. DC271 enables direct detection of the binding between unlabeled compounds and related retinoid-binding proteins via fluorescence competition assays (Ex/Em = 355 nm/460 nm) .
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-
- HY-D2008
-
|
|
Fluorescent Dye
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Others
|
|
ATTO 488 amine is an amine derivative of ATTO 488, the maximum excitation/emission wavelength: 500/520 nm.
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-
- HY-D2798A
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG1000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG1000-SH can be used for fluorescent labeling and imaging .
|
-
- HY-D2143
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-D2798
-
|
|
Fluorescent Dye
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Others
|
|
FITC-PEG400-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG400-SH can be used for fluorescent labeling and imaging .
|
-
- HY-D1387
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose .
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-
- HY-132264
-
|
|
Fluorescent Dye
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Others
|
|
FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
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-
- HY-D1440
-
|
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Fluorescent Dye
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Others
|
|
Rhodamine B, tetramethyl-, isothiocyanate (Tetramethylrhodamine B isothiocyante) is a fluorescent dye. Rhodamine B, tetramethyl-, isothiocyanate has a strong two-photon absorption at about 830 nm .
|
-
- HY-D2696
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 HA (MW 500000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
-
- HY-D2222
-
|
|
Fluorescent Dye
|
Others
|
|
5-HMSiR-Hoechst is a DNA probe. 5-HMSiR-Hoechst comprises Hoechst 33258 and spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). 5-HMSiR-Hoechst can stain living cells. Ex/Em=640 nm/675 nm .
|
-
- HY-D1702
-
|
|
Fluorescent Dye
|
Others
|
|
Mag-Fura-2 tetrapotassium is a cell-impermeant UV excitable rational fluorescent Mg 2+/Ca 2+ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg 2+ and Ca 2+ concentrations .
|
-
- HY-D2512
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-W324406
-
|
|
Fluorescent Dye
|
Others
|
|
1,2-Diamino-3,4-ethylenedioxybenzene is a carbonyl-reactive fluorometric labeling agent.
|
-
- HY-D0813
-
|
|
Fluorescent Dye
|
Others
|
|
Zincon sodium is an excellent colorimetric reagent for the detection of zinc and copper ions in aqueous solution. Zincon sodium can be used for the determination of zinc, copper, and cobalt ions in metalloproteins .
|
-
- HY-172398
-
|
|
Fluorescent Dye
|
Others
|
|
FAM phosphoramidite, 5-isomer is a standard fluorescein (FAM) phosphoramidite for 5'-terminal oligonucleotide labeling, high isomeric purity single isomer.
|
-
- HY-D2518
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG10000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG10000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
-
- HY-D2545
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG10000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-101894
-
|
DHR 123
|
Fluorescent Dye
|
Others
|
|
Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
|
-
- HY-D2842C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG3400-biotin can be used for fluorescent labeling and imaging .
|
-
- HY-D1161
-
|
NCI 240899
|
Fluorescent Dye
|
Neurological Disease
|
|
True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival .
|
-
- HY-D2535
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2802
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D1686
-
|
Biotin-16-UTP tetralithium
|
DNA Stain
|
Others
|
|
Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .
|
-
- HY-D2120
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D2640
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5 HA (MW 5000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
-
- HY-D1930
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 Azide is an azide derivative of ATTO 425, the maximum excitation and emission wavelength: 439/489 nm. ATTO 425 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D0853
-
DiAzKs
1 Publications Verification
H-L-Photo-lysine
|
Fluorescent Dye
|
Others
|
|
DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe .
|
-
- HY-D1355
-
|
|
Fluorescent Dye
|
Others
|
|
Azide cyanine dye 728 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1252
-
|
|
Fluorescent Dye
|
Others
|
|
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
|
-
- HY-D2795B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG5000-COOH can be used for fluorescent labeling and imaging .
|
-
- HY-151774
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .
|
-
- HY-D0071
-
|
|
Fluorescent Dye
|
Others
|
|
N-4-(5,6-Dimethoxy-N-phthalimidinyl)phenylmaleimide is a fluorescence reagent for labeling thiol .
|
-
- HY-D2673
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 HA (MW 55000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
-
- HY-156306
-
|
|
Fluorescent Dye
|
Others
|
|
Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
-
- HY-D2739
-
|
|
Fluorescent Dye
|
Others
|
|
SIMA phosphoramidite, 6-isomer is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA has higher stability during deprotection under alkaline conditions.
|
-
- HY-D2620
-
|
|
Photosensitizer
Reactive Oxygen Species (ROS)
Ferroptosis
|
Cancer
|
|
CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models .
|
-
- HY-D1633A
-
|
|
Fluorescent Dye
|
Others
|
|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
|
-
- HY-D1530
-
|
|
Fluorescent Dye
|
Others
|
|
4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide is a fluorogenic substrate for detecting α-N-acetylglucosaminidase .
|
-
- HY-D1988
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 Biotin is a biotin derivative of ATTO 620 with maximum excitation/emission wavelengths: 620/642 nm.
|
-
- HY-104056
-
|
|
Fluorescent Dye
|
Others
|
|
Fura Red is a Ca 2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca 2+] .
|
-
- HY-D2856C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
-
- HY-D0041
-
|
Calcein acetoxymethyl ester
|
Fluorescent Dye
|
Cancer
|
|
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
|
-
- HY-D2224
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5 dUTP is a dUTP far-infrared fluorescent dye containing sulfonated Cyanine5.5 group .
|
-
- HY-D1572
-
|
|
Fluorescent Dye
|
Others
|
|
Carbostyril 165 is an electronically neutral fluorescent dye (Ex: 351/364 nm, Em: >400 nm) .
|
-
- HY-134620
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
|
-
- HY-D2501
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7-N3 is a Sulfo Cy7-azide, which is a fluorescent dye. Sulfo Cy7-N3 can be used in cell imagine by Click reaction. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1085
-
|
|
Fluorescent Dye
|
Others
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-D2607
-
|
|
Fluorescent Dye
|
Others
|
|
ICG PEG5000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG5000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
-
- HY-D2060
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
-
- HY-D0824A
-
|
Sulfo-Cyanine7 Succinimidyl Ester triethylamine
|
Fluorescent Dye
|
Others
|
|
CY7-SE triethylamine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2851A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG-CHOL (MW 3400) is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG-CHOL (MW 5000) is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em = 488/525 nm) .
|
-
- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor® 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .\n
|
-
- HY-138226
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
|
-
- HY-D1113
-
|
|
Fluorescent Dye
|
Others
|
|
TFAX 488,TFP is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,TFP yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
|
-
- HY-DY3004
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Frozen Section Embedding Medium is a water-soluble mixture of polyethylene glycol and polyvinyl alcohol, widely used in immunohistochemistry experiments. Frozen Section Embedding Medium supports tissue during frozen sectioning, increasing tissue continuity and reducing wrinkling and fragmentation.
|
-
- HY-D2507
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG5000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG5000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
-
- HY-D0030
-
|
|
Fluorescent Dye
|
Others
|
|
2-Anthracenylsulfonyl chloride is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-P1362F
-
|
Cy5-Amyloid β Peptide (42-1)(human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
-
- HY-W345148
-
-
- HY-D0265
-
|
|
Environmental Pollutants
Fluorescent Dye
|
Others
|
|
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .
|
-
- HY-D0896AR
-
|
NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)
|
Bacterial
Reference Standards
|
Infection
|
|
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
-
- HY-W020030
-
|
|
Fluorescent Dye
|
Others
|
|
4-Amino-3,6-disulfonaphthalic anhydride dipotassium is a building block that can be used to systhese a useful dye for biological research purposes.
|
-
- HY-D1639A
-
-
- HY-D0896A
-
|
NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium
|
Bacterial
|
Infection
|
|
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
-
- HY-W354821
-
|
4-MUD
|
Fluorescent Dye
|
Metabolic Disease
|
|
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .
|
-
- HY-W357142
-
-
- HY-D2100
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-DSPE is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
|
-
- HY-W440916
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
|
-
- HY-W142117
-
|
|
Fluorescent Dye
|
Others
|
|
H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0080
-
|
|
Fluorescent Dye
|
|
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
|
-
- HY-D1533
-
|
|
Fluorescent Dye
|
|
RhoNox-1 is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe 2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe 2+ in living cells, and tends to be localized in the Golgi apparatus .
|
-
- HY-D0085
-
|
|
Fluorescent Dye
|
|
DiSC3(5) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3(5) is up to 622/670 nm. DiSC3(5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC50 value is 8 μM. DiSC3(5) in the presence of Na +/K +-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .
|
-
- HY-126561
-
|
CMFDA
|
Fluorescent Dye
|
|
Green CMFDA is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .
|
-
- HY-D1041
-
|
ICG-OSu
|
Fluorescent Dye
|
|
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-W751238
-
|
DMMB
|
Fluorescent Dye
|
|
Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye. Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin, releasing DMMB and increasing the fluorescence intensity. Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E. Coli) endotoxin . Dimethyl methylene blue zinc chloride double salt can be used for the quantification of sulfated glycosaminoglycans .
|
-
- HY-110210
-
|
BODIPY FL,SE
|
Fluorescent Dye
|
|
BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
|
-
- HY-43520
-
|
|
Fluorescent Dye
|
|
BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .
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- HY-DY1046
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Fluorescent Dye
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Green CMFDA (solution) is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .
Solvent and concentration: DMSO: 10 mM
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- HY-D1458
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Fluorescent Dye
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Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .
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- HY-D0133
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Fluorescent Dye
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NBD-X acid is a fluorescent probe containing a nitrobenzoxadiazole group. NBD-X acid can be used to study the structure and function of biomolecules .
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- HY-D0807
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5-IAF
1 Publications Verification
5-Iodoacetamidofluorescein
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Fluorescent Dye
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5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains) .
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- HY-D2367
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N-Hydroxysuccinimidyl rhodamine B ester
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Fluorescent Dye
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Rhodamine B NHS ester (N-Hydroxysuccinimidyl rhodamine B ester) is an amine-reactive fluorescent probe (λex/λem: 564/589 nm, respectively). Rhodamine B NHS ester could react with Glycine (HY-Y0966) .
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- HY-135009
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DASPI
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Fluorescent Dye
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2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .
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- HY-D1506
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Fluorescent Dye
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Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-115691
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Styrene-BODIPY; Styrene-Conjugated BODIPY
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Fluorescent Dye
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STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .
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- HY-DY1025
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Fluorescent Dye
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Laurdan (solution) is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.
Solvent and concentration: DMSO: 5 mM
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- HY-W088089
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Fluorescent Dye
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ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
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- HY-D1046
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Dabcyl, SE
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Fluorescent Dye
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Dabcyl acid, SE is the amine-reactive form of Dabcyl acid (DABCYL) (HY-D1045), and is widely used in the preparation of fluorescent probes containing DABCYL .
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- HY-D1694
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Fluorescent Dye
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LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH .
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- HY-DY1030
-
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Fluorescent Dye
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RhoNox-1 (solution) is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe 2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm). FeRhoNox-1 can enter the cell well, suitable for the detection of Fe 2+ in living cells, and tends to be localized in the Golgi apparatus .
Solvent and concentration: DMSO: 5 mM
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- HY-D1602
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Fluorescent Dye
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BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λex=505 nm, λem=511 nm) .
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- HY-118155
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ACMA
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Fluorescent Dye
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9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
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- HY-D1459
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Fluorescent Dye
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BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .
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- HY-W013967
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Fluorescent Dye
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1,6-Diphenylhexa-1,3,5-triene is a membrane intercalator and hydrophobic fluorescent probe. 1,6-Diphenylhexa-1,3,5-triene intercalates into the non-polar region of lipid bilayers of adipocyte membranes with probe/membrane equilibrium affected by temperature, probe concentration, and membrane concentration. 1,6-Diphenylhexa-1,3,5-triene’s fluorescence intensity correlating with adipocyte membrane probe incorporation (Ex/Em = 350/452 nm) .
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- HY-113870
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Fluorescent Dye
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6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques .
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- HY-130015
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Fluorescent Dye
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HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
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- HY-130017
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Fluorescent Dye
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HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
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- HY-129811
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Fluorescent Dye
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Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a Kd of 2 μM . Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations .
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- HY-D0941
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Fluorescent Dye
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5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .
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- HY-D2312
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Fluorescent Dye
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Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .
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- HY-124197
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Fluorescent Dye
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Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
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- HY-D2864
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Fluorescent Dye
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Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
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- HY-151776
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TZ-Cy3
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Fluorescent Dye
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Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .
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- HY-171179
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Fluorescent Dye
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BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo .
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- HY-W040681
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Fluorescent Dye
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7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .
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- HY-147889
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Fluorescent Dye
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BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .
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- HY-D1151
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HKOH-1
3 Publications Verification
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Fluorescent Dye
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HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
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- HY-D1265
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HClO-green
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Fluorescent Dye
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EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
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- HY-136957
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Fluorescent Dye
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Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with Kds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively .
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- HY-DY1072
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ICG-OSu (solution)
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Fluorescent Dye
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ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
Solvent and concentration: DMSO: 10 mM
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- HY-D1478
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Fluorescent Dye
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Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
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- HY-D2476
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Fluorescent Dye
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H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
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- HY-U00440
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- HY-D1302
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Fluorescent Dye
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Near-IR fluorescent probe-1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2418
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Fluorescent Dye
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PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .
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- HY-D1631A
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Fluorescent Dye
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Calcium green-5N hexapotassium is a cell-impermeant Ca 2+-sensitive fluorescent probe. Calcium green-5N hexapotassium shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
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- HY-130022
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Fluorescent Dye
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|
HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
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- HY-151890
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Fluorescent Dye
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NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .
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- HY-D1254
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NBL-SS perchlorate
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Fluorescent Dye
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Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .
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- HY-D2267
-
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Fluorescent Dye
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JF646-Hoechst is a fluorescent red DNA probe that is an ideal substitute for large oligonucleotide-coupled antibodies used in PAINT experiments, especially for bacterial studies. JF646-Hoechst excitation/emission maximum =655/670 nm .
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- HY-130027
-
HKOCl-4
1 Publications Verification
BXY2142
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Fluorescent Dye
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HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity . HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm.
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- HY-D1460
-
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Fluorescent Dye
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Fluorescein Di-β-D-Glucuronide is an orally active fluorescent probe substrate and an indicator of β-glucuronidase (βG) activity in intestinal bacteria. Fluorescein Di-β-D-Glucuronide can be used for non-invasive time-lapse optical imaging of βG activity in intestinal bacteria in nude mice. Fluorescein Di-β-D-Glucuronide supports the quantitative analysis of bacterial βG enzyme activity and inhibition .
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- HY-101937C
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Fluorescent Dye
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(±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
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- HY-D2377
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Fluorescent Dye
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F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .
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- HY-D1883
-
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Fluorescent Dye
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Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-P3791
-
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Fluorescent Dye
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N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .
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- HY-D0159
-
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Fluorescent Dye
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ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn 2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm .
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- HY-D0159A
-
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Fluorescent Dye
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ZnAF-1F tetraTFA is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F tetraTFA can be used as fluorescent probes for Zn 2+ in cells. ZnAF-1F tetraTFA shows λ excitation of 489 nm and λ emission of 514 nm .
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- HY-D1595
-
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Fluorescent Dye
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BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .
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- HY-D2317
-
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Fluorescent Dye
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HaloFlipper 30 is a fluorescent probe that covalently reacts with HaloTag fusion proteins to form an ester bond, which allows the probe to be stably attached to membrane structures. HaloFlipper 30 has high specificity, precision and good cell permeability .
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- HY-151801
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Fluorescent Dye
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DIBA-Cy5 is a fluorescent DIBA antagonist made up be DIBA-alkyne binding Cyanine5 fluorophores (Cy5) and polyethylene glycol (PEG) biomolecules. DIBA-Cy5 can serve as a fluorescent ligand, suitable for probe attachment through click chemistry. DIBA-Cy5 exerts a high binding affinity to type-2 mAChR (M2R) with the Kd value of 1.80 nM, can directly stain M2R receptors in the sinoatrial node of a mouse heart .
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- HY-135640
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Fluorescent Dye
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TAMRA-probe 1 is a commonly used fluorescent probe for labeling .
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- HY-101937A
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Fluorescent Dye
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(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
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- HY-W337618
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Fluorescent Dye
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7-Aminocoumarin is highly fluorescent, acts as an optical brightener and fluorescent probe .
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- HY-D2115
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Fluorescent Dye
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NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .
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- HY-D1391
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PbS/CdSe QD
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Fluorescent Dye
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PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window .
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- HY-D1609
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Fluorescent Dye
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BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .
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- HY-D2999
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Fluorescent Dye
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NIR-RED ATP Probe is a NIR-II fluorescent probe. NIR-RED ATP Probe exhibits high affinity and selectivity for ATP and can non-invasively and with high contrast detect changes in ATP concentration at the cellular level, with minimal interference to the abundant biomolecules within the cells. NIR-RED ATP Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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- HY-D1591
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Fluorescent Dye
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BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .
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- HY-D3000
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Fluorescent Dye
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NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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- HY-W020798
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Fluorescent Dye
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1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma .
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- HY-D2280
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Fluorescent Dye
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Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .
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- HY-D1883A
-
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Fluorescent Dye
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Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-147177
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Fluorescent Dye
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BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .
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- HY-D2474
-
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Fluorescent Dye
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PSP is a two-photon fluorescent probe for selective and sensitive detection of H2Sn in live cells and tumor spheroids (Ex/Em = 440/640 nm). PSP can be utilized in ferroptosis research .
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- HY-D2260
-
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Fluorescent Dye
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hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .
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- HY-D2322
-
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Fluorescent Dye
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SupraFlipper 31 is a fluorescent probe. SupraFlipper 31 can be released in the membrane of interest (MOI) via chemical stimulation.
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- HY-162129
-
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Fluorescent Dye
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Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .
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- HY-W012642A
-
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Fluorescent Dye
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2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence .
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- HY-D1527
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Fluorescent Dye
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N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
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- HY-W411215
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Fluorescent Dye
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1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .
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- HY-151544
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Fluorescent Dye
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PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .
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- HY-D2964
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Fluorescent Dye
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NBzF-BG is a novel H2O2-specific fluorescent probe. NBzF-BG shows visible absorption centered at 505 nm and weak fluorescence with an emission maximum at 525 nm. NBzF-BG is covalently and selectively conjugated with the SNAP-tag protein, leading to formation of the fluorophore-protein conjugate (SNAP-NBzF). SNAP-NBzF rapidly reacts with H2O2 and thereby shows an enhancement in fluorescence .
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- HY-D2376
-
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Fluorescent Dye
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|
BH-Vis is a two-photon fluorescent probe that inhibits cell plasma membrane (CPM). BH-Vis has great potential to accurately identify pyroptosis at the cellular level during AAA development in the mouse abdominal aortic aneurysm AAA model .
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- HY-D1770
-
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Fluorescent Dye
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NBD Dihexadecylamine is a fluorescent probe used for labeling phospholipids.
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- HY-D1898
-
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Fluorescent Dye
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6-TET Azide is a fluorescent probe that can be used for the preparation of fluorescent contrast agent and nucleic acid sequencing .
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- HY-135637
-
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Fluorescent Dye
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Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
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- HY-D1528
-
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Fluorescent Dye
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MTSEA-Fluorescein is a fluorescent probe that can be used for ion channel research .
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- HY-D2943
-
|
SNAP-SS-SulfoCy3
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Fluorescent Dye
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BG-SS-SulfoCy3 is a SulfoCy3-labeled SNAP tag fluorescent probe, which is linked by a disulfide bond to achieve selective labeling and controllable cleavage. BG-SS-SulfoCy3 can be used to study the endocytosis and trafficking of membrane proteins such as GPCRs .
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- HY-D3011
-
|
2-(9-Anthroyloxy)stearic acid
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Fluorescent Dye
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|
2-AS is a fluorescent probe and can monitor the microenvironment and dynamic changes of biofilms .
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- HY-130510
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Fluorescent Dye
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6-HEX dipivaloate is an amino-bindable fluorescent probe that can be used to label peptides and oligonucleotides. 6-HEX dipivaloate is widely used in nucleic acid sequencing and related research .
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- HY-D3239
-
|
AF405; Alexa Fluor 405 succinimidyl ester
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Fluorescent Dye
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AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1 .
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- HY-B0389F1
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Fluorescent Dye
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FITC-D-Glucose is a fluorescently labeled glucose derivative and an orally effective bacterial metabolic activity detection probe. FITC-D-Glucose is applicable to the research of cholera .
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- HY-D3267
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Fluorescent Dye
|
|
ACu1 is a copper (I)-selective two-photon fluorescent probe that enables the visual imaging of Cu + distribution in living cells and tissues .
|
- HY-D2941
-
|
SNAP-AF
|
Fluorescent Dye
|
BGAF (SNAP-AF) is a fluorescent diacetyl fluorescein-labeled SNAP tag fluorescent probe, specifically designed for the covalent labeling of SNAP-tag fusion proteins in living cells. BGAF utilizes the specific reaction of the human DNA repair protein hAGT to achieve specific fluorescent labeling of the target protein in the living cell environment .
|
- HY-D3007
-
|
|
Fluorescent Dye
|
|
LD-CK is a fluorescent probe based on a coumarin-chromone structure, specifically designed to visualize lipid droplet polarity changes and endowed with multimodal imaging capability. LD-CK contains a high-performance lipophilic coumarin moiety, which enables it to specifically target lipid droplets upon cellular entry while minimizing background fluorescence to the greatest extent. LD-CK has an excitation wavelength (Ex) of 488 nm and an emission wavelength (Em) of 540 nm (in low-polarity environments such as toluene) or 640 nm (in high-polarity environments such as glycerol), with its emission peak undergoing a redshift as solvent polarity increases .
|
- HY-D3180
-
|
|
Fluorescent Dye
|
|
CDr20 is a fluorescent chemical probe capable of crossing the blood-brain barrier. CDr20 undergoes glucuronidation catalyzed by the UDP-glucuronosyltransferase Ugt1a7c, which triggers a fluorescence turn-on response. CDr20 enables visualization of live microglial cells. CDr20 can be used for research on Alzheimer's disease, stroke, and autism .
|
- HY-D2967
-
|
|
Fluorescent Dye
|
|
Golgi-NO is a Golgi-targeted fluorescent probe for nitric oxide (NO) (Ex/Em: 560 nm/589 nm). Golgi-NO exhibits excellent selectivity for various potential interfering substances. Golgi-NO can be used to study the function of NO within the Golgi apparatus in disease models such as Alzheimer's disease (AD) .
|
- HY-D3152
-
|
|
Fluorescent Dye
|
|
NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
|
- HY-D1707
-
|
|
Fluorescent Dye
|
|
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .
|
- HY-D1892
-
|
|
Fluorescent Dye
|
|
6-Hexachloro-fluorescein phosphoramidite is a fluorescent probe that can be used for oligonucleotide labeling .
|
- HY-W127843
-
|
|
Fluorescent Dye
|
|
Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg 2+ detection .
|
- HY-135639
-
|
|
Fluorescent Dye
|
|
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D1090
-
|
|
Fluorescent Dye
|
|
JOE is a xanthene fluorophore (i.e., 4′,5′-dichloro-2′,7′-dimethoxy-5 (6)-carboxyfluorescein; 2',7'-dimethoxy-4',5'-dichloro-6-carboxyfluorescein) with an absorption wavelength of approximately 525 nm and an emission wavelength of approximately 550 nm. The fluorescence quantum yield of JOE correlates with the rigidity of the linker arm and the distance to dG nucleoside. JOE is commonly used as a fluorescent label for oligonucleotides and molecular beacon probes, and also serves as the acceptor fluorophore in fluorescence energy transfer primers for DNA sequencing .
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- HY-W321446
-
|
|
Fluorescent Dye
|
|
Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change .
|
- HY-D1470
-
|
|
Fluorescent Dye
|
|
BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe .
|
- HY-D0993
-
|
Nonylacridine orange
|
Fluorescent Dye
|
|
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
|
- HY-175131
-
|
|
Fluorescent Dye
|
|
Prostaglandin D2-biotin is a fluorescent probe that can be used for detecting PGD2.
|
- HY-D1117
-
|
NADA hydrochloride
|
Fluorescent Dye
|
|
NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation .
|
- HY-W127775
-
|
|
Fluorescent Dye
|
|
Demethyl Rhod-2 AM is a fluorescent mitochondrial probe (λex=552 nm, λem=581 nm).
|
- HY-D2133
-
|
Alendronate-Cy5
|
Fluorescent Dye
|
|
Cy5-ALN (Alendronate-Cy5) is a fluorescently labeled bisphosphonate probe .
|
- HY-D0149
-
|
|
Fluorescent Dye
|
|
4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes .
|
- HY-DY1021
-
|
|
Fluorescent Dye
|
DiSC3 (5) (solution) is a fluorescent probe commonly used as a tracer dye to evaluate mitochondrial membrane potential. The excitation/emission wavelength of DiSC3 (5) is up to 622/670 nm. DiSC3 (5) can inhibit the respiratory system associated with mitochondrial NAD, and the IC50 value is 8 μM. DiSC3 (5) in the presence of Na +/K +-ATPase inhibitor ouabain 2 can induce membrane hyperpolarization of Ehrlich ascites tumor cells .
Solvent and concentration: DMSO: 1 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-W800698
-
|
|
Fluorescent Dye
|
|
BP Fluor 430 Alkyne is a green-fluorescent alkyne-activated probe routinely used for imaging of moderate to high abundance azide-containing biomolecules. BP Fluor 430 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near 430 nm. This probe is water-soluble and its fluorescence is pH independent over a wide pH range.
|
- HY-D1022A
-
|
Biotin-16-deoxyuridine-5'-triphosphate trisodium
|
Fluorescent Dye
|
|
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
- HY-D1022
-
|
Biotin-16-deoxyuridine-5'-triphosphate
|
Fluorescent Dye
|
|
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
- HY-D2930
-
|
SNAP-SS-SulfoCy5
|
Fluorescent Dye
|
|
BG-SS-SulfoCy5 (SNAP-SS-SulfoCy5) is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond. BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .
|
- HY-D2379
-
|
|
Fluorescent Dye
|
HMRG is a type of hydroxymethyl rhodamine green fluorescent scaffold, featuring an open non-cyclic structure. HMRG can produce significant dynamic fluorescence changes through a one-step enzymatic reaction at physiological pH, which is useful for developing various probes. Fluorescent probes based on HMRG can be used for fluorescence detection of diseases such as tumors and diabetic nephropathy .
|
- HY-D1752
-
|
D-22421
|
Fluorescent Dye
|
|
JC-9 (D-22421) is a green-fluorescent probe used for ratiometric calculation of mitochondrial membrane potential.
|
- HY-D1089
-
|
|
Fluorescent Dye
|
|
6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .
|
- HY-D1751
-
|
|
Fluorescent Dye
|
|
RIM-1 is a fluorescent probe for protein kinase C (PKC) that can be used to visualize the distribution of PKC in cells.
|
- HY-135634
-
|
|
Fluorescent Dye
|
|
GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
|
- HY-D2022
-
|
|
Fluorescent Dye
|
|
ATTO 514 is a new type of hydrophilic fluorescent probe with strong stability and maximum excitation/emission wavelength: 511/531 nm.
|
- HY-104058
-
|
Green 488 BAPTA 1AM
|
Fluorescent Dye
|
|
BAPTA Green 1AM (Oregon Green 488 BAPTA 1AM) is a fluorescent Ca 2+ indicator that consists of a green fluorescent probe OG 488 and a cell-permeable Ca 2+ chelator BAPTA AM.
|
- HY-D2290
-
|
|
Fluorescent Dye
|
|
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
|
- HY-130025
-
HKOCl-3
2 Publications Verification
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Fluorescent Dye
|
|
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm .
|
- HY-D2287
-
|
|
Fluorescent Dye
|
|
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
- HY-D0786
-
|
|
Fluorescent Dye
|
|
3-Morpholinobenzanthrone is a fluorescent membrane probe, possessing higher dipole moment values in the excited-state than in the ground-state .
|
- HY-D2287A
-
|
|
Fluorescent Dye
|
|
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
- HY-108715
-
|
|
Fluorescent Dye
|
|
Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
|
- HY-D1158
-
|
|
Fluorescent Dye
|
|
HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl) .
|
- HY-D1765
-
|
|
Fluorescent Dye
|
|
FM 1-43FX is a fluorescent membrane probe that contains an aliphatic amine which can react with aldehyde-based fixatives.
|
- HY-D2775
-
|
|
Fluorescent Dye
|
|
Cobalt(II) ions probe 1 (Compound L) is a fluorescent sensor for Co 2+ detecting in biological environments. Cobalt(II) ions probe 1 can selectively bind with Co 2+ in the presence of other metal ions (Ex: 380 nm) .
|
- HY-D1518
-
- HY-D0938
-
|
CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
|
Fluorescent Dye
|
|
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus .
CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
|
- HY-D0251
-
|
Uranine
|
Fluorescent Dye
|
|
Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
|
- HY-D0099
-
|
|
Fluorescent Dye
|
|
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
|
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dye
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
- HY-141646
-
|
|
Fluorescent Dye
|
|
MIT-PZR is a mitochondria-targeted,? low cytotoxicity fluorescent probe that can be used in live cells and in vivo imaging. Ex / Em = 485 / 705 nm
|
- HY-DY1078
-
|
|
Fluorescent Dye
|
Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipin (λex: 489 nm, λem: 525 nm).
Solvent and concentration: DMSO: 10 mM
|
- HY-103469
-
|
PO1
|
Fluorescent Dye
|
|
Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye .
|
- HY-N7131
-
|
|
Fluorescent Dye
|
|
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
|
- HY-W800696
-
|
|
Fluorescent Dye
|
|
BP Fluor 430 Azide is a water-soluble, green-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
BP Fluor 430 is a bright, photostable, green-fluorescent probe with excitation near its absorption maximum at 432 nm and emission maximum at 539 nm. This probe is water soluble and pH-insensitive from pH 4 to pH 10.
A next generation probe, BP Fluor 430 Picolyl Azide, is also available for detection of low abundance alkyne-tagged biomolecules.
|
- HY-135635
-
|
|
Fluorescent Dye
|
|
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
|
- HY-D1377
-
|
|
Fluorescent Dye
|
|
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .
|
- HY-D2327
-
|
|
Fluorescent Dye
|
|
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively) .
|
- HY-D2315
-
|
|
Fluorescent Dye
|
|
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
|
- HY-102055
-
|
|
Fluorescent Dye
|
|
JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd value of 0.2 μM .
|
- HY-D1255
-
|
|
Fluorescent Dye
|
|
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells .
|
- HY-157036
-
|
|
Fluorescent Dye
|
|
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .
|
- HY-D2479
-
|
|
Fluorescent Dye
|
|
DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO −) in living cells .
|
- HY-116215
-
|
|
Fluorescent Dye
|
|
2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
|
- HY-D2289
-
|
|
Fluorescent Dye
|
|
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .
|
- HY-U00451
-
|
|
Fluorescent Dye
|
|
ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).
|
- HY-D1759
-
|
|
Fluorescent Dye
|
|
Fura-4F AM is a cell-permeant fluorescent calcium indicator. Upon entering the cell, this probe is hydrolyzed by cytosilic esterases and trapped as the active chelator.
|
- HY-130013
-
|
|
Fluorescent Dye
|
|
HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .
|
- HY-D2288
-
|
|
Fluorescent Dye
|
|
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .
|
- HY-D2762
-
|
|
Fluorescent Dye
|
|
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
|
- HY-D0127
-
|
|
Fluorescent Dye
|
|
Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm) .
|
- HY-D1883B
-
|
|
Fluorescent Dye
|
|
Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
- HY-D1457
-
|
|
Fluorescent Dye
|
|
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .
|
- HY-D1266
-
|
NO-red
|
Fluorescent Dye
|
|
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
|
- HY-D2274
-
|
|
Fluorescent Dye
|
|
EZH2-AF647 is a fluorescent probe derived from UNC2239 that improves receptor TR-FRET properties by using Alexa 647 dye .
|
- HY-D1623
-
|
|
Fluorescent Dye
|
|
Cyanine3 carboxylic acid chloride is a non-toxic red fluorescent dye with good solubility in organic solvents. Cyanine3 carboxylic acid chloride can be used as a non-reactive fluorophore for experimental control and calibration. Cyanine3 carboxylic acid chloride can also be synthesized with targeted agents as fluorescent probes for rapid detection of agent reactions .
|
- HY-D2525
-
|
|
Fluorescent Dye
|
|
Cy3-PEG-DMPE is a fluorescent probe that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and DMPE (HY-142983). Cy3-PEG-DMPE is widely used in biomolecule labeling, cell imaging and liposome research.
|
- HY-D2970
-
|
|
Fluorescent Dye
|
|
Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression .
|
- HY-W012642
-
|
|
Fluorescent Dye
|
|
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics .
|
- HY-D0140
-
|
ETH 5294
|
Fluorescent Dye
|
|
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .
|
- HY-D1683
-
NBD-PE
2 Publications Verification
|
Fluorescent Dye
|
|
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .
|
- HY-D1148
-
|
|
Fluorescent Dye
|
|
HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO - in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
|
- HY-D2921
-
|
|
Fluorescent Dye
|
|
BODIPY-FL-Vindoline is a high-affinity fluorescent probe for the pregnane X receptor (PXR), with a Kd of 256 nM. BODIPY-FL-Vindoline can be used in the research of drug metabolism and drug-drug interactions .
|
- HY-144603
-
|
|
Fluorescent Dye
|
|
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y 1 receptor (Y 1R), with a Ki of 0.19 nM .
|
- HY-D1781
-
|
|
Fluorescent Dye
|
|
NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis .
|
- HY-D1159
-
|
|
Fluorescent Dye
|
|
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .
|
- HY-103684
-
|
Real Thiol-NH2
|
Fluorescent Dye
|
|
RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
|
- HY-101859
-
NucPE1
5 Publications Verification
Nuc-H2O2 Probe
|
Fluorescent Dye
|
|
NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
|
- HY-D0251R
-
|
Uranine (Standard)
|
Fluorescent Dye
|
|
Fluorescein (Standard) is the analytical standard of Fluorescein. This product is intended for research and analytical applications. Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes .
|
- HY-128868G
-
|
|
Fluorescent Dye
|
|
FITC-Dextran (MW 150000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). FITC-Dextran (MW 150000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 150000) can be used in perfusion studies in animals or in fluorescence microlymphography, to study processes that affect the permeability of the blood brain barrier (BBB) . FITC-Dextran (MW 150000) can be used as fluorescent probe to study cell permeability .
|
- HY-DY1019
-
|
|
Fluorescent Dye
|
2-NBDG (solution) is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
Solvent and Concentration: Sterile PBS: 5 mM
|
- HY-158779
-
|
SSP4
|
Fluorescent Dye
|
|
Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe 2+, Fe 3+, Mg 2+, Ca 2+, and Zn 2+) .
|
- HY-D1257
-
|
Msr-green
|
Fluorescent Dye
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Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (λex=375 nm, λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells .
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- HY-W248119
-
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Fluorescent Dye
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8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY is a BODIPY derivative that can be used as a fluorescent probe for GFP-labeled muscarinic M1 receptor .
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- HY-D1157
-
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Fluorescent Dye
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HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
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- HY-149835
-
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Fluorescent Dye
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TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .
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- HY-D1493
-
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Fluorescent Dye
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FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor .
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- HY-D3003
-
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Fluorescent Dye
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M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F₆₅₀/F₅₆₀) within the range of 0-40 μM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases .
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- HY-D2878
-
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Fluorescent Dye
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MitoPeDPP is a mitochondrial-targeted fluorescent probe that is sensitive to LPO. MitoPeDPP is synthesized from diphenylpyrenephosphine. MitoPeDPP can be used to study the occurrence of mitochondrial LPO in RSL3-induced oligodendrocyte ferroptosis .
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- HY-D0029
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5(6)-AFM; Fluoresceinamine mixed isomers
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Fluorescent Dye
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5(6)-Aminofluorescein (5(6)-AFM) is an amino-containing fluorescein dye primarily used for biomolecular labeling, fluorescence imaging, and as a precursor for the synthesis of fluorescent probes (Ex/Em = 495/515 nm).
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- HY-D1526
-
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Fluorescent Dye
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N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
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- HY-112526
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Fluorescent Dye
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Thiofluor 623 (Compound 3) is a fluorescent turn-on probe that can be used for the selective sensing and bioimaging of thiols. Thiofluor 623 displays excellent immunity to interference from nitrogen and oxygen nucleophiles. Thiofluor 623 is essentially nonfluorescent in the absence of thiols, which cleave the probe and release the red-emissive donor-acceptor fluorophore (Ex=563 nm, Em=623 nm) .
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- HY-W800692
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Fluorescent Dye
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BP Fluor 350 Azide is a blue-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets.
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- HY-D1244
-
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Fluorescent Dye
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CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd 2+ to Pd 0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer .
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- HY-D1570
-
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Fluorescent Dye
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BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
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- HY-D0027R
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Coumarin 120 (Standard); AMC (Standard)
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Fluorescent Dye
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7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
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- HY-W074143
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Fluorescent Dye
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Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
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- HY-W040143
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Fluorescent Dye
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2',7'-Dichlorofluorescein is an important fluorescent product in the detection of oxidative stress and can be used to measure reactive oxygen species (ROS) (Ex=503 nm and Em=523 nm) .
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- HY-D1106
-
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Fluorescent Dye
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BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
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- HY-D0027
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Coumarin 120; AMC
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Fluorescent Dye
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7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
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- HY-W011664
-
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DPBF
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Fluorescent Dye
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1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
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- HY-135636
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Fluorescent Dye
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Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2119
-
CQ-Lyso
2 Publications Verification
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Fluorescent Dye
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CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .
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- HY-D1093
-
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Fluorescent Dye
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Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .
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- HY-D3157
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Fluorescent Dye
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Photoactive esterase probe is a photoactivatable fluorescent probe for esterase. Photoactive esterase probe is used for the detection and imaging of esterase activity in living cells .
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- HY-D2266
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Fluorescent Dye
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FluoBar1 is an imaging fluorescence probe modified by a barbiturate ligand with fluorescent coumarin. FluoBar1 can monitor L-type voltage-gated calcium channels (LTCC) in living cells in real time for the study of neurological diseases .
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- HY-118213
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Fluorescent Dye
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N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
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- HY-N7131R
-
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Fluorescent Dye
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Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .
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- HY-101859R
-
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Nuc-H2O2 Probe (Standard)
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Fluorescent Dye
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NucPE1 (Standard) (Nuc-H2O2 Probe (Standard)) is the analytical standard of NucPE1 (HY-101859). This product is intended for research and analytical applications. NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
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- HY-D1256
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Fluorescent Dye
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Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm) .
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- HY-D2756
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Fluorescent Dye
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OG 488 alkyne is a bright, green-fluorescent alkyne-activated probe routinely used for imaging of azide-containing biomolecules. OG 488 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
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- HY-D1443
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(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
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Fluorescent Dye
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BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
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- HY-D0921
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ADS 815EI
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Fluorescent Dye
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Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes .
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- HY-133705
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Fluorescent Dye
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Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90 (Ex/Em = 488/515 nm) .
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- HY-D3404
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Fluorescent Dye
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BODi-1 is a fluorescent modulator targeting dsDNA, which binds to dsDNA via a bis-intercalation mechanism (Ex=465 nm, Em=490 nm). BODi-1 exhibits a fluorescence enhancement effect upon binding to nucleic acids, but its fluorescence intensity, anisotropy and average lifetime decrease at higher dye/DNA ratios. When BODi-1 binds to DNA in liposome complexes, it also shows red-shifted emission spectra, along with reduced quantum yield and average lifetime. BODi-1 does not induce significant DNA conformational changes when the dye/DNA ratio is below 0.01. BODi-1 can be used as a fluorescent probe for the characterization of liposome complexes and FRET studies at this ratio .
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- HY-DY1102
-
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Fluorescent Dye
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BODIPY FL-C16 (solution) is a BODIPY-labeled analog of Palmitic acid (HY-N0830), which serves as a fluorescent lipid tracer. BODIPY FL-C16 (solution) also acts as a ligand for liver fatty acid-binding protein (L-FABP) and intestinal fatty acid-binding protein (I-FABP) , with Kd values of 270 nM and 330 nM, respectively. BODIPY FL-C16 (solution) is rapidly taken up by cells, and after metabolic conversion to phospholipids, it is incorporated into the membrane structures of intracellular organelles and extracellular vesicles .
Solvent and concentration: DMSO: 5 mM
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- HY-113285F
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Fluorescent Dye
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FITC-Ureidopropionic acid is labeled with FITC fluorescent label on Ureidopropionic acid. FITC-Ureidopropionic acid is a fluorescent probe used to label biomolecules or cells.
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- HY-151704
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Fluorescent Dye
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ICG-alkyne is a short-wave infrared (SWIR)-emitting cyanine fluorescent probe based on alkyne-derivatized indocyanine green. ICG-alkyne can undergo click chemistry reaction to conjugate with antibody molecules via binding to the azide groups introduced into antibodies. ICG-alkyne enables SWIR fluorescent molecular imaging of breast tumors in living mice. ICG-alkyne can be used in breast cancer-related research .
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- HY-D1745
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fac-[Re(CO)3(phen)L]
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Fluorescent Dye
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Liptracker-green (fac-[Re(CO)3(phen)L]) is a cell-permeable fluorogenic probe that localizes to polar lipids, and can be used to label lipid droplets and other high lipid-content compartments in live and fixed cells using fluorescent microscopy.
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- HY-15942
-
5-TAMRA
3 Publications Verification
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Fluorescent Dye
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5-TAMRA can produce bright, pH-insensitive orange-red fluorescence (excitation and emission extremes of 546/579) and has good photostability. 5-TAMRA is mainly used as a fluorescent marker for the synthesis and study of specific oligonucleotide probes .
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- HY-W800704
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Fluorescent Dye
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BP Fluor 594 alkyne is a bright, red-fluorescent alkyne-activated probe routinely used for imaging of azide-containing biomolecules. BP Fluor 594 alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
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- HY-126793
-
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DCFH2-DA
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Fluorescent Dye
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2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon .
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- HY-W013435
-
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Fluorescent Dye
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1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic nitric oxide (NO) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO .
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- HY-D1877
-
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Fluorescent Dye
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ZY-1 is a control molecule of ZY-2 (HY-D1876, a PKM2 fluorescent probe). ZY-1 shows a low fluorescence emission in HeLa, a cervical cancer cell abundant in PKM2 expression .
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- HY-108715R
-
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Fluorescent Dye
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Real Thiol (Standard) is the analytical standard of Real Thiol (HY-108715). This product is intended for research and analytical applications. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
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- HY-D1264
-
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Zn-green
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Fluorescent Dye
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PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn 2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn 2+ in living cells .
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- HY-D3319
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Fluorescent Dye
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BHQ‑3 carboxylic acid is an azo‑containing dark fluorescence quencher. BHQ‑3 carboxylic acid is conjugated to an MMP‑cleavable peptide and paired with a fluorophore to form an activatable probe for MMP activity detection in vitro. BHQ‑3 carboxylic acid shows maximal absorption in the 620 to 730 nm range. BHQ‑3 carboxylic acid–based fluorescent probes can be used in the research of arthritis and tumor‑related pathological processes. .
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- HY-D3392
-
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Fluorescent Dye
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Thalidomide-cyanine 5 is a fluorescent probe prepared by conjugating the CRBN binder Thalidomide (HY-14658) with the near-infrared fluorescent dye Cy5. Thalidomide-cyanine 5 binds to DDB1-CRBN protein complex with a Kd of 121.6 nM. Thalidomide-cyanine 5 binds to CRBN to form a binary complex, and is mainly used for the visual tracking research of degradants such as PROTAC (Ex/Em = 650/665 nm) .
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- HY-D1617
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Fluorescent Dye
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BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
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- HY-D1378
-
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Fluorescent Dye
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C-Laurdan is a modified Laurdan (HY-D0080) probe that imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan can be used in research of lipid arrangement and fluidity in biological membranes or artificial lipid membranes .
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- HY-D2297
-
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Fluorescent Dye
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AIE-GA is a Golgi apparatus (GA) fluorescent probe (green channel: λex = 405 nm, λem = 500-700 nm). AIE-GA has a favourable binding ability to interact with COX-2. AIE-GA binds to the cyclooxygenase catalytic site of COX-2 .
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- HY-D2345
-
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Fluorescent Dye
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GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors .
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- HY-151644
-
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Fluorescent Dye
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Fluorescein hydrazide is a sensitive fluorescent probe for Hg 2+ and Co 2+ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM [2][3].
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- HY-D0154
-
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Tetramethylrhodamine-6-isothiocyanate
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Fluorescent Dye
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6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .
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- HY-D1055
-
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Fluorescent Dye
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MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.
Excitation/emission wavelength: 510/580 nm.
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- HY-D1876
-
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Fluorescent Dye
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ZY-2 is a specific fluorescent probe for pyruvate kinase M2 (PKM2). ZY-2 can image in PKM2-positive cells in a time- and concentration-dependent manner. ZY-2 can be used for the detection of cancer cells .
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- HY-DY1048
-
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Fluorescent Dye
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DAF-FM DA (Diaminofluorescein-FM diacetate) (solution) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
Solvent and concentration: DMSO: 2 mM
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- HY-D0943
-
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Kernechtrot
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Fluorescent Dye
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Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium . Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine .
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- HY-D0090
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Fluorescent Dye
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MQAE is a chloride ion (Cl -) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) .
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- HY-D1756
-
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Fluorescent Dye
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ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
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- HY-D2299
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Fluorescent Dye
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AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum .
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- HY-D2755
-
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Fluorescent Dye
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BP Light 650 carboxylic acid is an vibrant far-red fluorochrome with comparable or improved performance over other dyes, including BP Fluor 647 and Cy5 dye, for fluorescent applications. It is used to label antibodies and other proteins as molecular probes for cellular imaging and other fluorescence detection methods application.
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- HY-D0816
-
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RH-123; R-22420
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D0984
-
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-101876
-
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D0984A
-
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T668
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-DY1044
-
|
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Fluorescent Dye
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HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
Solvent and concentration: DMSO: 50 mM
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- HY-D0985A
-
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Tetramethylrhodamine ethyl ester perchlorate
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D0309
-
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Basic Red 1
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D1412
-
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Fluorescent Dye
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LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .
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- HY-D0151
-
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Fluorescent Dye
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Tetramethylrhodamine-5-maleimide is a fluorescent probe with high specificity for cysteine thiol (SH) groups. Tetramethylrhodamine-5-maleimide has high sensitivity, responds rapidly to negatively charged nanoparticles, and shows a concentration-dependent decrease in fluorescence intensity, but it is susceptible to interference from humic acids .
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- HY-D1428
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Fluorescent Dye
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Di-4-ANEPPDHQ is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].
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- HY-D1532
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Fluorescent Dye
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DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite .
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- HY-D1625
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Fluorescent Dye
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Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction . Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-DY1089
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Fluorescent Dye
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Di-4-ANEPPDHQ (solution) is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].
Solvent and concentration: DMSO: 5 mM
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- HY-D2201
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Fluorescent Dye
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Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .
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- HY-W127703
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Fluorescent Dye
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Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
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- HY-D2279
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Fluorescent Dye
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NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively .
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- HY-D2477
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Fluorescent Dye
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Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
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- HY-D2616
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Fluorescent Dye
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ICG PEG2000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG2000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
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- HY-D1631
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Fluorescent Dye
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Calcium Green-5N AM is a Ca 2+-sensitive fluorescent probe (Kd = 14 μM). Calcium Green-5N AM shows enhanced fluorescence intensity upon binding to Ca 2+, and it can monitor free Ca 2+ in neurons .
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- HY-150978
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Fluorescent Dye
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DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .
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- HY-D2617
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Fluorescent Dye
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ICG PEG5000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG5000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
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- HY-DY1023
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 10 mM
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- HY-D1275
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Fluorescent Dye
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CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
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- HY-DY1042
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 10 mM
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- HY-15940
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5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
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Fluorescent Dye
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5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
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- HY-DY1054
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Fluorescent Dye
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 5 mM
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- HY-D1156
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Fluorescent Dye
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HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
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- HY-D2286
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Fluorescent Dye
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HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
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- HY-D0986
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Fluorescent Dye
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TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
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- HY-D1156A
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Fluorescent Dye
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HKSOX-1m (5/6-mixture) hydrobromide is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells .
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- HY-133876
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DiA
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Fluorescent Dye
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4-Di-16-ASP is a green fluorescent membrane dye. 4-Di-16-ASP is a lipophilic aminostyryl probe with a broad emission spectrum (can be detected with green, orange or even red filters). It is commonly used for neuronal membrane tracing (it diffuses faster than DiO) .
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- HY-117401
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Fluorescent Dye
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5-Dodecanoylaminofluorescein is an amphipathic (amphoteric) fluorescent probe (Ex/Em = 485 nm/515-535 nm), which consists of a hydrophilic fluorescein core and a hydrophobic dodecanoyl group (C12 fatty acid chain) linked by an amide bond. 5-Dodecanoylaminofluorescein is mainly used as an interface-localized radical trapping/indicator probe. Dodecanoylaminofluorescein can be used for the determination of the antioxidant properties of emulsions, or can serve as a lipophilic drug model for the study of passive skin penetration when encapsulated in tyrosine-derived nanospheres .
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- HY-DY1053
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Fluorescent Dye
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1,3-Diphenylisobenzofuran (DPBF) (solution) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-W800838
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Fluorescent Dye
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BP Fluor 488 Tetrazine is a bright, green-fluorescent probe used for detection TCO-tagged biopolymers. BP Fluor 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre?targeted cell labeling studies where rapid reaction kinetics is a must BP Fluor 488 Tetrazine probe would of great value.
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- HY-D1393
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Pb:Ag2Se
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Fluorescent Dye
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Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution .
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- HY-D3193
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Fluorescent Dye
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CDg4 is a green fluorescent probe and member of the fluorescent diamino-chalcone library.CDg4 binds to glycogen on mouse embryonic stem cell colony surfaces .
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- HY-D1735
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Golgi-Red Tracke
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Fluorescent Dye
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The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. BODIPY TR Ceramide (Golgi-Red Tracke) is a Golgi-specific fluorescent dye, which can visualise individual cells . Ex/Em=589 nm/616 nm.
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- HY-D1612
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Fluorescent Dye
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The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye . BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells . Ex/Em= 505 nm/512 nm.
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- HY-D1259
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VDP-green (NEP)
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Fluorescent Dye
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NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λex/λem=430/535 nm). NEP has the potential for parkinsonism .
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- HY-D2285
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Fluorescent Dye
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MOR-CES2 is a near-infrared fluorescent probe (Ex= 630 nm, Em=735 nm) capable of identifying cancer cells and tissues, as well as exhibiting a sensitive response to inflammation. MOR-CES2 holds potential as an efficient imaging tool in assisting surgical resection of CES2-related tumors .
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- HY-DY1040
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Fluorescent Dye
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LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
Solvent and concentration: DMSO: 1 mM
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- HY-103684R
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Real Thiol-NH2 (Standard)
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Fluorescent Dye
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RT-NH2 (Standard) is the analytical standard of RT-NH2 (HY-103684). This product is intended for research and analytical applications. RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
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- HY-D2549
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Fluorescent Dye
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Cy5-PEG5000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-D2548
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Fluorescent Dye
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Cy5-PEG2000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-D3008
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Fluorescent Dye
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ALP Green (Probe 4) is an amphiphilic ALP fluorescent probe (Em = 550 nm). ALP Green can be used in the research of APAP (HY-66005)-induced liver injury .
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- HY-150087
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Fluorescent Dye
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Ctrl-CF4-S2 is a chemically modified control probe of the copper probe Copper Fluor-4 (CF4, HY-150086), in which two of the four thioether ligands in CF4 (HY-150086) are replaced with methylene groups. CF4 (HY-150086) is a fluorescent probe used for detecting the presence and distribution of copper ions, whereas Ctrl-CF4-S2 does not respond to copper ions. This allows it to eliminate background signals from copper, thereby helping to determine whether the signals from CF4 (HY-150086) accurately reflect the dynamic changes of copper ions in biological systems
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- HY-D3381
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Fluorescent Dye
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MitoCLox is a mitochondria-targeted ratiometric fluorescent probe for measuring mitochondrial inner membrane lipid peroxidation .
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- HY-D3240
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Fluorescent Dye
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Photoactive NTR probe (Compound 1) is a covalent crosslinker and Fluorescent indicator targeting Nitroreductase. The Photoactive NTR probe undergoes a sequential activation process: it is first activated via nitroreductase-mediated nitro-to-amino conversion, and then forms a fluorescent product upon photoactivation. The Photoactive NTR probe can form covalent adducts with the side chains of cysteine, tyrosine, lysine and histidine in adjacent proteins to reduce fluorophore diffusion. The Photoactive NTR probe enables super-resolution (STORM) imaging of active mitochondrial nitroreductase microdomains in living cells .
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- HY-143218
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Tetraphenylethene maleimide
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Fluorescent Dye
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TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .
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- HY-DY1024
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Fluorescent Dye
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TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM
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- HY-D2522
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Fluorescent Dye
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Cy3-PEG5000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-W856375
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Fluorescent Dye
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(E)-BSPOTPE is the E configuration of BSPOTPE (HY-W856375A). BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
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- HY-D1296
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Fluorescent Dye
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Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
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- HY-D2521
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Fluorescent Dye
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Cy3-PEG2000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-129420
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Fluorescent Dye
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WSP-5 is a H2S-selective fluorescent probe (Ex/Em = 502/525 nm). WSP-5 enables visual monitoring of H2S released and accumulated from peptide-H2S donor conjugates in glioma cells. WSP-5 is applicable to glioma research .
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- HY-D2004
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Fluorescent Dye
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ATTO 488 streptavidin is a fluorescent reagent that specifically targets and binds to biotin (biotin), formed by the conjugation of ATTO 488 with streptavidin (HY-P3152). ATTO 488 streptavidin enables visualization of the activity of streptavidin immobilized on the surface of polymeric nanoparticles, or acts as a fluorescent probe to detect the selective binding and internalization process of anti-HB-EGF/NA with cells expressing HB-EGF (with no such effect on cells that do not express this receptor). ATTO 488 streptavidin effectively verifies the function of streptavidin conjugated to the surface of nanoparticles and is suitable for research related to atherosclerotic cardiovascular diseases .
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- HY-D1671
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Fluorescent Dye
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TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .
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- HY-D2572
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Fluorescent Dye
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Cy5.5-PEG5000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-D2571
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Fluorescent Dye
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Cy5.5-PEG2000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-DY1057
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Fluorescent Dye
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TMA-DPH (solution) is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined .
Solvent and concentration: DMSO: 10 mM
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- HY-D1547
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Fluorescent Dye
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1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea (compound 1a) can be used as a fast-responsive fluorescent gold ion probe for detection of gold ions in water and synthetic products .
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- HY-W856375A
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Fluorescent Dye
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BSPOTPE is the mixture of (E)-BSPOTPE (HY-W856375) and (Z)-BSPOTPE. BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
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- HY-D1832
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VF 532 Tyramide
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Fluorescent Dye
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Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1835
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VF 594 Tyramide
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Fluorescent Dye
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Vari Fluor 594 TSA (200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1833
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VF 680 Tyramide
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Fluorescent Dye
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Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1831
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VF 620 Tyramide
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Fluorescent Dye
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Vari Fluor 620 TSA (200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D3004
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Fluorescent Dye
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GSH Tracker Probe (CPDSA) is a cyanine-based fluorescent probe with a NIR emission that is specific for GSH (excitation: 635 nm; emission: 655-755 nm). CPDSA can monitor and image GSH levels in live cells and in vivo .
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- HY-W800699
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Fluorescent Dye
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BP Fluor 430 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 430 DBCO is an ideal alternative to copper requiring fluorescent alkynes.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near its absorption maximum at 432 nm. Its emission peak at 539 nm is pH independent over a wide pH range.
BP Fluor DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.
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- HY-D2338
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Fluorescent Dye
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PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .
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- HY-159529
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DBCO-PEG4-Eosin Y
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Fluorescent Dye
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DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.
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- HY-DY1058
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Fluorescent Dye
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2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) (solution) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D1258
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VDP-green
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Fluorescent Dye
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AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
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- HY-D0153
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Fluorescent Dye
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Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
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- HY-DY1082
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Fluorescent Dye
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Green DND-26 (solution) is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
Solvent and concentration: DMSO: 2 mM
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- HY-D1464
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CH1055
1 Publications Verification
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Fluorescent Dye
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CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-125749
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Fluorescent Dye
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Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λex = 430 nm, λem = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes .
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- HY-D1837
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VF 488 Tyramide
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Fluorescent Dye
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Vari Fluor 488 TSA（200×） (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1834
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VF 640 Tyramide
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Fluorescent Dye
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Vari Fluor 640 TSA（200×） (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D1838
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VF 350 Tyramide
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Fluorescent Dye
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Vari Fluor 350 TSA（200×） (VF 350 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-D3226
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Fluorescent Dye
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Zinc (II) probe-1 (Compound DNP) is a dual-color Fluorescent probe that can simultaneously monitor Zn 2+ and H +. Upon interaction with Zn 2+, Zinc (II) probe-1 produces bright blue fluorescence (excitation wavelength: 405 nm; blue channel wavelength: 420-500 nm). Upon interaction with H +, Zinc (II) probe-1 exhibits red fluorescence (excitation wavelength: 561 nm; red channel emission wavelength: 630-730 nm). Zinc (II) probe-1 can be used in studies related to depression .
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- HY-D2944
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- HY-D3266
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Fluorescent Dye
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IR 650 DBCO is a far-red-fluorescent probe, pH-insensitive, azide-reactive probe routinely used for imaging of azide-containing biomolecules without the need for a copper catalyst. (Ex=651nm, Em=668 nm)
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- HY-D0309R
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Basic Red 1 (Standard)
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Fluorescent Dye
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Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
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- HY-D1464A
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Fluorescent Dye
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CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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- HY-DY1009
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Fluorescent Dye
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CFDA-SE (solution) is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
Solvent and concentration: DMSO: 5 mM
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- HY-D2344
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3-Benzothiazole-daphnetin
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Fluorescent Dye
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3-BTD (3-Benzothiazole-daphnetin) is a Catechol-O-methyltransferase (COMT) two-photon fluorescence probe. 3-BTD can also be used for biological imaging of endogenous COMT in living cells and tissue sections .
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- HY-D2339
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Fluorescent Dye
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H-FluNox is a selective fluorescent probe that senses labile heme using biomimetic N-oxide deoxygenation to trigger fluorescence. H-FluNox is more than 100-fold selective for labile heme over Fe(II), enabling the discrimination of labile heme from labile Fe(II) pools in living cells. H-FluNox is sensitive enough to detect the subcellular labile heme. (λex=490 nm, λem=535 nm)
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- HY-D2769
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Difluorocarboxyfluorescein azide, 6-isomer
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Fluorescent Dye
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Oregon green 488 azide (Difluorocarboxyfluorescein azide, 6-isomer) is a bright green fluorescent azide-activated probe that reacts with terminal alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). Oregon green 488 azide can label goat anti-mouse IgG and exhibits excellent luminescence efficiency. Oregon green 488 azide, as a streptavidin conjugate, is used for flow cytometry staining of macrophages .
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- HY-D2945
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Fluorescent Dye
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CLIP-Biotin is a Biotin-labeled CLIP tag fluorescent probe. CLIP-Biotin can be used for marking the CLIP-tag fusion proteins in cells.
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- HY-141511
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Fluorescent Dye
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Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
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- HY-D0040
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Fluorexon
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Fluorescent Dye
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Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
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- HY-111330
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HPF; 3'-p-(Hydroxyphenyl) fluorescein
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Fluorescent Dye
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Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
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- HY-128692
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Fluorescent Dye
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Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-125452
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Fluorescent Dye
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DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
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- HY-W127715
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Fluorescent Dye
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Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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- HY-D3216
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Fluorescent Dye
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ER-Cu (II) is an endoplasmic reticulum-selective fluorescent Cu 2+ probe. ER-Cu (II) localizes specifically to the endoplasmic reticulum of hepatocytes .
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- HY-D2931
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Fluorescent Dye
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SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe, specifically designed for live-cell protein labeling and real-time imaging applications .
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- HY-D2951
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Fluorescent Dye
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BG-Kaede chromophore (Compound 4c) is a SNAP-tag-specific fluorescent probe, which is designed and synthesized using the chromophore of the red fluorescent protein Kaede as a template. BG-Kaede chromophore can be used as a tool for visualizing proteins in living cells .
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- HY-128868D
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Fluorescent Dye
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FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-128868A
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Fluorescent Dye
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FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-151708
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Fluorescent Dye
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CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2341
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Fluorescent Dye
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6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
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- HY-128868
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Fluorescent Dye
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FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
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- HY-D2204
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Fluorescent Dye
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SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe 3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .
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- HY-D1094
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SNARF 1
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Fluorescent Dye
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Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH (Ex: 488 nm). Carboxy-SNARF 1 (5/6-mixture) can be used for measurement pH. Carboxy-SNARF 1 (5/6-mixture) exhibits a significant emission shift from yellow-orange (Em: 580 nm) to deep red fluorescence (Em: 640 nm) under acidic and basic conditions (pH=7-8), respectively .
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- HY-DY1087
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Fluorescent Dye
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Coppersensor 1 (solution) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
Solvent and concentration: DMSO: 2 mM
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- HY-W800697
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Fluorescent Dye
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BP Fluor 430 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site will dramatically increase the rate of CuAAC reaction without the need to increase concentration of azide reagent or copper.
In addition, the use of BP Fluor 430 Picolyl Azide instead of conventional BP Fluor 430 Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling.
In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
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- HY-W800693
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Fluorescent Dye
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BP Fluor 405 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site dramatically increases the rate of CuAAC reaction without increasing the concentrations of azide reagent or copper.
In addition, the use of picolyl azide instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling.
In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
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- HY-D0896
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ANS
1 Publications Verification
ANSA; 8-Anilino-1-naphthalenesulfonic acid
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Fluorescent Dye
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ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×10 6 M -1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .
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- HY-D2959
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CLIP-DF
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Fluorescent Dye
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BC-DF is a diacetyl fluorescein labeled CLIP tag fluorescent probe. BC-DF can be used for labeling CLIP-tag fusion protein in cells .
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- HY-D2960
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CLIP-OG
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Fluorescent Dye
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BC-OG is an oregon green labeled CLIP tag fluorescent probe. BC-OG can be used for labeling CLIP-tag fusion protein in cells .
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- HY-W800701
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Fluorescent Dye
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BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes.
BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.
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- HY-D3002
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Fluorescent Dye
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ONOO-/O2- tracker probe is a dual-responsive near-infrared fluorescent probe. ONOO-/O2- tracker probe will only emit a strong fluorescence signal when both peroxynitrite (ONOO⁻) and superoxide anion (O₂•⁻), the two key reactive oxygen/nitrogen species, are present simultaneously. ONOO-/O2- tracker probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
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- HY-D2413
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BODIPY FL PEG4-VH032
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Fluorescent Dye
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BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a Kd value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .
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- HY-D1274
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Fluorescent Dye
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Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D0989
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Fluorescent Dye
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Rhod-2 is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
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- HY-D1274B
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Fluorescent Dye
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Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-133821
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Fluorescent Dye
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N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
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- HY-DY1016
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Fluorescent Dye
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FITC-Dextran (MW 10000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
Solvent and Concentration: Sterile water: 2 mM
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- HY-D1274C
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Fluorescent Dye
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Sulfo-cyanine3 azide potassium is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide potassium can be used for synthesis of fused tricyclic heterocycles, producing immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-DY1035
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Fluorescent Dye
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Hydroxyphenyl Fluorescein (HPF) (solution) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
Solvent and concentration: DMSO: 10 mM
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- HY-DY1018
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Fluorescent Dye
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FITC-Dextran (MW 4000) (solution) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption .
Solvent and Concentration: Sterile water: 2 mM
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- HY-D1274A
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Fluorescent Dye
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Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D3141
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Fluorescent Dye
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DR probe is a "dual-key-and-lock" fluorescent probe designed based on the Resorufin (HY-123533) scaffold (Ex/Em = 647 nm/663-738 nm). DR probe can be sequentially activated by hydrogen peroxide to form the intermediate SR, which acts as a tyrosinase substrate to trigger a fluorescence turn-on signal. DR probe can distinguish normal melanocytes from melanoma cells. DR probe supports cell imaging and can be applied to mouse melanoma models to achieve melanoma diagnosis with higher accuracy and lower false-positive rates. DR probe is applicable to relevant research on melanoma .
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- HY-D1903
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Fluorescent Dye
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Fura Red AM is a fluorescent probe that can be used to visualize Ca 2+ distribution in the cytoplasm of undifferentiated cells. Fura Red AM operates at an excitation wavelength of 488 nm .
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- HY-D3194
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Fluorescent Dye
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CDy14 is a fluorescent probe targeting the extracellular polysaccharide Psl. CDy14 enables the detection of biofilms. CDy14 can be used for research on chronic bacterial infections .
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- HY-175074
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Fluorescent Dye
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C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium is a fluorescently labeled GM1 ganglioside probe. C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium can be used as a probe in biological experiments .
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- HY-D3306
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Fluorescent Dye
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Tubulin-RedTracker is a paclitaxel-derived fluorescent microtubule-binding probe. Tubulin-RedTracker induces F-actin cytoskeleton defects at relatively high concentrations. (Ex/Em = 652/669) .
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- HY-DY1020
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Fluorescent Dye
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Rhod-2 (solution) is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
Solvent and concentration: DMSO: 1 mM
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- HY-DY1075
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Fluorescent Dye
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N-Methylmesoporphyrin IX (NMM) (solution) , a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
Solvent and concentration: DMSO: 2 mM
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- HY-W800694
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Fluorescent Dye
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BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
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- HY-D1422
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BDNCA-346
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Fluorescent Dye
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ER Tracker Yellow is an endoplasmic reticulum-targeted temperature-visible fluorescent probe. ER Tracker Yellow has high temperature sensitivity (3.9%/°C) and is not affected by pH and Ca 2+ interference. ER Tracker Yellow can be used for real-time monitoring of local temperature changes in the ER area. ER Tracker Yellow maintains its function in fixed cells. ER Tracker Yellow is suitable for various cell lines and primary cells, such as HeLa cells, MEF cells, and other cells .
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- HY-D3377
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LysoRhoNox
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Fluorescent Dye
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HMRhoNox-M (LysoRhoNox) is a selective fluorescent probe for labile Fe 2+ with an orange fluorescence, and its excitation/emission wavelength is λₑₓ/λₑₘ = 555/575 nm. HMRhoNox-M undergoes N-oxide deoxygenation mediated by Fe 2+, converting from a non-fluorescent spirocyclic closed form to a fluorescent quinone open form. HMRhoNox-M is used to detect labile Fe 2+ in living cells .
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- HY-D1583
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DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate
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Fluorescent Dye
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Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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- HY-145746
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Fluorescent Dye
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Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
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- HY-128536
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Fluorescent Dye
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KMG-104AM is a Mg 2+ fluorescent probe. KMG-104AM is a membrane-permeable ester-modified derivative of KMG-104, which serves as a reporter and imaging agent. KMG-104AM can track the increase in intracellular free magnesium ion concentration induced by mitochondrial uncoupling. KMG-104AM enables visualization of the three-dimensional distribution of intracellular magnesium ion concentration. KMG-104AM is applicable to research related to the functions of intracellular magnesium ions .
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- HY-149203
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Fluorescent Dye
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MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO -, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO - (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .
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- HY-120993
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1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium
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Fluorescent Dye
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1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .
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- HY-D2729
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Fluorescent Dye
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Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent probe that specifically labels Mycobacterium tuberculosis (Mtb). Cy3-NO2-tre generated fluorescence after activation by a specific nitroreductase, Rv3368c, which is conserved in the Mycobacteriaceae. Cy3-NO2-tre effectively imaged mycobacteria within infected host cells, tracked the infection process, and visualized Mycobacterium smegmatis being endocytosed by macrophages (Ex/Em= 540-550/575-625 nm) .
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- HY-DY1014
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Fluorescent Dye
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ATP-Red 1 (solution) is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).
Solvent and concentration: DMSO: 1 mM
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- HY-D2948
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Fluorescent Dye
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SNAP-430 is a (diethylamino) coumarin-labeled SNAP tag fluorescent probe. SNAP-430 can be used for making SNAP-tag fusion proteins inside living cells, on cell surfaces, or in vitro.
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- HY-D2346
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Fluorescent Dye
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HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
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- HY-DY1091
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Fluorexon (solution)
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Fluorescent Dye
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Calcein (solution) (Fluorexon (solution)) is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
Solvent and concentration: DMSO: 2 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-15534
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CBIC2
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Fluorescent Dye
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JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
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- HY-D3314
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NBD-SAG
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Fluorescent Dye
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1-NBD-Stearoyl-2-arachidonoyl-sn-glycerol (NBD-SAG) is a fluorescently labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol (HY-131897). 1-NBD-Stearoyl-2-arachidonoyl-sn-glycerol acts as a fluorescent probe for the measurement of DGKε enzymatic activity .
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- HY-D2443
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Fluorescent Dye
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AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
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- HY-D2997
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Fluorescent Dye
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1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H2S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H2S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H2S activation .
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- HY-DY1068
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Fluorescent Dye
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Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
Solvent and concentration: DMSO: 10 mM
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- HY-D3253
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Fluorescent Dye
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IR 650 azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 azide is a terminal azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 633nm, Em = 647nm)
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- HY-D2965
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SPG1
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Fluorescent Dye
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SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
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- HY-D3265
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Fluorescent Dye
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IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm
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- HY-W356116
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Nbd-ceramide
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Fluorescent Dye
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C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism .
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- HY-D2985
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Fluorescent Dye
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MI-BP-CC is a mitochondrial-targeting near-infrared fluorescent probe. MI-BP-CC can specifically localize in the mitochondria of living cells. MI-BP-CC visualizes viscosity with an emission wavelength of 722 nm for detecting mitochondrial viscosity .
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- HY-D2094
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Fluorescent Dye
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PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
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- HY-D2952
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Fluorescent Dye
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BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca 2+ concentration and serves as a highly sensitive Ca 2+ fluorescent indicator .
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- HY-D3221
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Fluorescent Dye
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MAO Probe 1 is a reactive two-photon fluorescent probe capable of crossing the blood-brain barrier, which is used to detect the activity of monoamine oxidases (MAO-A/MAO-B), with Km values of 70 μM (MAO-A) and 75 μM (MAO-B), respectively. IBC 2 (benzo[g]imino-coumarin 2), the enzymatic product of MAO Probe 1, can further specifically bind to and image Aβ plaques, enabling in vivo two-photon co-monitoring of MAO activity and Aβ plaques. MAO Probe 1 can be used in Alzheimer's disease research (IBC 2: Ex/Em = 850 nm/570-620 nm) .
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- HY-125623
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Fluorescent Dye
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MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].
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- HY-D0717
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Diaminofluorescein-FM diacetate
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Fluorescent Dye
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DAF-FM DA (Diaminofluorescein-FM diacetate) is a fluorescent probe for the detection and bioimaging of nitric oxide (NO). DAF-FM DA spontaneously crosses the plasma membrane and is subsequently cleaved by esterases to generate intracellular DAF-FM (Ex/Em=495/515 nm) .
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- HY-D2975
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Fluorescent Dye
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TTVP is a high-performance, blood activated AIE near-infrared fluorescent probe. TTVP can display hemorrhagic areas in the mouse brain with ultra sensitivity and high contrast specificity. TTVP provides a visual assessment tool for the study of hemorrhagic conditions .
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- HY-D3233
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Fluorescent Dye
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Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
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- HY-B1422
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Aminacrine
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Fluorescent Dye
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9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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- HY-D3311
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Fluorescent Dye
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M1219 is a GSH/ATP dual near-infrared activated fluorescent probe that enables independent real-time monitoring of dynamic changes in intracellular GSH and ATP without spectral crosstalk (GSH: Ex=640 nm, Em=740~800 nm; ATP: Ex=594 nm/610 nm, Em=650~700 nm). M1219 not only visualizes the metabolic regulatory mechanism of TNBC under single/dual-target inhibition of SLC7A11/GLUT1 and accurately evaluates its in vivo efficacy, but also achieves precise localization of the TNBC tumor invasion boundary. M1219 can be used for the research of triple-negative breast cancer .
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- HY-D0150
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Fluorescent Dye
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Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
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- HY-DY1073
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Fluorescent Dye
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MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state) , and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction) .
Solvent and concentration: DMSO: 2 mM
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- HY-D3254
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Fluorescent Dye
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IR 650 picolyl azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 picolyl azide is a terminal picolyl azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 650nm, Em = 670nm)
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- HY-D2976
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Fluorescent Dye
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CN-N2 is a visible light fluorescent probe. CN-N2 has high selectivity, rapid penetration, good biocompatibility, and imaging effects. CN-N2 is suitable for intraoperative rapid imaging of atherosclerotic plaque .
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- HY-D2991
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Fluorescent Dye
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CDG-DNB3 is a selective fluorescent probe for Mycobacterium tuberculosis. CDG-DNB3 provides rapid and specific labeling of live Mycobacterium tuberculosis. CDG-DNB3 can image Bacillus Calmette-Guérin phagocytosis in real time .
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- HY-D3241
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Fluorescent Dye
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|
CD649.2 is a red-emitting copper-targeted acylimidazole-reactive Fluorescent probe and a highly specific Cu 2+ detection reagent. CD649.2 enables visualization of labile Cu 2+ pools and their dynamic changes in living cells .
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- HY-D3263
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Fluorescent Dye
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|
IR 650 NHS ester is a far-red-fluorescent probe with NHS ester. NHS ester is the most popular amine-reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. (Ex=651nm, Em=668 nm)
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- HY-131045
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HCC-Amino-D-alanine hydrochloride
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Fluorescent Dye
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HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
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- HY-D3198
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Fluorescent Dye
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NIR-fluorescent ceramide is a neutral near-infrared (NIF) fluorescent probe (λem=650 nm) based on the C-bridged nitrobenzoxadiazole SCOTfluor core, which enables visualization of lipid metabolic processes such as sphingolipid trafficking. The emission signal of NIR-fluorescent ceramide increases significantly in liposomal environments. NIR-fluorescent ceramide acts as an intracellular trafficking tracer, localizing to regions surrounding the endoplasmic reticulum and Golgi apparatus within a short period, and then translocating to recycling lysosomes over a longer period, thus enabling real-time visualization of sphingolipid trafficking and biological lipid functions in living cells. NIR-fluorescent ceramide also generates metabolic uptake profiles and provides multiple metabolic readouts in human cancer cell lines .
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- HY-114354
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BOD FL alkyne
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Fluorescent Dye
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BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .
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- HY-D1991
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Fluorescent Dye
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ATTO 647 is a carborhodamine fluorophore and imaging tracer with photostable properties. ATTO 647 serves as a fluorescent probe to investigate cell membrane structure and diffusion characteristics. When conjugated with wheat germ agglutinin, ATTO 647 specifically binds to N-acetyl-β-D-glucosamine and sialic acid residues on membrane glycoproteins, enabling single-molecule tracing of glycoprotein diffusion. ATTO 647 exhibits highly stable fluorescence properties with significantly reduced blinking in mounting media such as ROXS (AA/MV) and ROXS (TX/TQ), whereas its brightness properties vary in Ibidi-MM and Vectashield. ATTO 647 can also be used to label histone H2B-GFP in fixed cells for confocal microscopy photobleaching experiments .
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- HY-D3214
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Fluorescent Dye
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NIR-Cu (Ⅱ) is a near-infrared fluorescent Cu 2+ probe. NIR-Cu (Ⅱ) enables fluorescence imaging of Cu 2+ in living mice. NIR-Cu (Ⅱ) reduces self-absorption and exhibits minimal photobleaching, thus supporting in vivo imaging applications .
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- HY-D2990
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Fluorescent Dye
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KSA01 is a two-dimensional fluorescent probe. KSA01 can detect SA-β-gal activity and sense lysosomal pH. KSA01 can accurately distinguish cellular aging from other pathological states with high expression of β-gal .
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- HY-D2946
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BC-TMR
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Fluorescent Dye
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CLIP-TMR (BC-TMR) is a TMR-labeled CLIP tag fluorescent probe. CLIP-TMR combines the high specificity recognition ability of the CLIP-tag and the excellent optical performance of the TMR fluorophore, and can be used for the specific labeling and visualization of the HCV NS5A protein .
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- HY-D2939
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Fluorescent Dye
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BGSBD is a SNAP-tag-based fluorescent probe (Ex/Em: 435 nm/516 nm) based on the environmentally sensitive fluorescent group SBD, specifically designed for protein labeling of live cells without washing. BGSBD achieves a 280-fold fluorescence enhancement after labeling by ingeniously utilizing the hydrophobic binding pocket of the SNAP-tag protein, providing an ideal tool for real-time monitoring of protein dynamics within cells .
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- HY-D3346
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Fluorescent Dye
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Dusquench1 NHS ester is an amino-reactive fluorescent quencher (it does not emit light and has no emission wavelength, Ex = 480-580 nM), specially designed for labeling proteins, oligonucleotides and other biopolymers containing primary amines. It is a core reagent in the fields of qPCR probes, FRET detection and molecular beacons.
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- HY-D3354
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Fluorescent Dye
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BP Fluor 350 alkyne is a blue fluorescent dye probe (Ex/Em = 346 nm/455 nm) that contains a terminal acetylene group (-C≡CH). BP Fluor 350 is specifically used for copper-catalyzed azide-alkyne cycloaddition and is employed to label azide groups in biological samples.
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- HY-DY1097
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Fluorescent Dye
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Thiazole Orange (solution) is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D3391
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Fluorescent Dye
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RMR-Tre is a fluorescent probe targeting the mycobacterial acyltransferase Ag85. Under the catalysis of Ag85, RMR-Tre undergoes 6-position mycoloylation and anchors to the mycobacterial membrane, while achieving fluorescence activation by inhibiting the intramolecular twisted charge transfer state transition. RMR-Tre can distinguish live mycobacteria from dead ones through metabolism-driven labeling, enabling rapid, wash-free, low-background detection of viable bacteria. RMR-Tre reports the drug resistance of Mycobacterium tuberculosis via the trehalose catalytic shift activity readout associated with TreS. In addition, RMR-Tre can be combined with flow cytometry or high-content imaging techniques to visualize and quantitatively analyze the metabolic heterogeneity of Mycobacterium tuberculosis related to persistence and drug resistance. RMR-Tre is widely used in tuberculosis-related research .
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- HY-B1422R
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Aminacrine (Standard)
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Fluorescent Dye
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9-Aminoacridine (Standard) is the analytical standard of 9-Aminoacridine. This product is intended for research and analytical applications. 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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- HY-D2988
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Fluorescent Dye
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BIN-3 is a novel near-infrared fluorescent probe. BIN-3 has excellent biocompatibility, no cytotoxicity, and no hemolysis. BIN-3 can be used for highly sensitive and selective imaging of drug-resistant bacterial infections expressing β-lactam enzymes in live mice .
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- HY-D1300
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LysoTracker Red DND-99
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Fluorescent Dye
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LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
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- HY-D3416
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TAMRA-2,4-dinitroaniline
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Fluorescent Dye
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TMR-DN (TAMRA-2,4-dinitroaniline) is a bright orange fluorescent probe that binds to the SRB-2 aptamer, with a Kd value of 35 nM for the SRB-2 aptamer. TMR-DN exhibits low background fluorescence, enabling wash-free live-cell RNA imaging .
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- HY-D0988
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R-PE
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Fluorescent Dye
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R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
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- HY-D2958
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Fluorescent Dye
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ZP1BG is a SNAP tag fluorescent probe for detecting Zn 2+, which is formed by the covalent connection of the zinc sensor ZP1 from the Zinpyr family with the benzyl guanine group. ZP1BG can be used to detect the concentration of Zn 2+ in neuronal organelles such as the Golgi apparatus and mitochondria .
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- HY-D3165
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Fluorescent Dye
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DCM-gal-CF is a fluorescent probe containing a DCM fluorophore scaffold and a D-galactose recognition moiety. DCM-gal-CF itself shows weak fluorescence, and its fluorescence is enhanced after cleavage by β-galactosidase. DCM-gal-CF can be used to detect β-galactosidase activity .
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- HY-D3173
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TPG-456
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Fluorescent Dye
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TP-α is a glucagon-selective two-photon fluorescent probe with a Kd of 65 μM. TP-α directly interacts with glucagon to produce significant fluorescence enhancement. TP-α selectively stains viable glucagon-secreting α cells in pancreatic islets, enabling visualization of their localization, distribution and availability. TP-α is applicable to diabetes research .
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- HY-D2987
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Fluorescent Dye
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BacGO is a highly selective, wash free fluorescent probe for Gram positive bacteria. BacGO binds to the carbohydrate structure in peptidoglycan through boric acid and exhibits depolymerization induced luminescence (DIE) properties. BacGO can be used for imaging complex environmental samples (such as activated sludge) and flat plate bacteria without affecting bacterial activity .
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- HY-D2971
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Fluorescent Dye
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NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells .
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- HY-D2983
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Fluorescent Dye
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ARHB is a highly selective and sensitive NAT2 fluorescent probe suitable for real-time detection of NAT2 activity in various bacteria. ARHB can successfully penetrate the bacterial cells, and the fluorescence intensity is positively correlated with the expression level of NAT2. ARHB is used for high-throughput screening of natural inhibitors for tuberculosis .
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- HY-D2938
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Fluorescent Dye
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BG-PEG11-Cya-NR is a high-performance, non washable, fluorescent opening probe. BG-PEG11-Cya-NR has very weak fluorescence in polar environments (such as aqueous solutions), while its fluorescence is significantly enhanced in non-polar environments (such as the lipid bilayer of cell membranes) .
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- HY-D1063
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Fluorescent Dye
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IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
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- HY-D2994
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SNAP-MaP555
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Fluorescent Dye
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SPY555-BG (SNAP-MaP555) is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
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- HY-D1509
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Fluorescent Dye
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Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
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- HY-D3234
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Fluorescent Dye
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Cy-AP is a hypoxia-sensitive near-infrared Fluorescent probe (emission wavelength: 725 nm). Cy-AP exhibits no fluorescence under normoxic microenvironments, while under hypoxic microenvironments, its azo group is reduced, releasing strong near-infrared fluorescence with an emission at 725 nm. Cy-AP enables visualization of intracellular hypoxic status through multiple imaging modalities .
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- HY-D3230
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Fluorescent Dye
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FLCS1 is a BODIPY-based Fluorescent probe and selective copper (I) ion binder (λex = 630 nm, λemis = 660 nm). Binding of FLCS1 to copper (I) ions induces fluorescence turn-on. Addition of copper (I) to a methanolic solution of FLCS1 causes a slight red shift (4 nm) in the maximum absorption wavelength (λmax) in the UV-Vis spectrum .
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- HY-D2940
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SiR650-BG
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Fluorescent Dye
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SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
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- HY-D0053
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6-Carboxy-X-rhodamine
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Fluorescent Dye
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6-ROX is a selective fluorescent probe and potential inhibitor of COX-2. 6-ROX binds to the active site of COX-2 and inhibits its conversion of arachidonic acid into prostaglandins. 6-ROX is often used in the field of optical imaging related to tumors and inflammation, and helps detect diseased tissues with high expression of COX-2 .
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- HY-D3166
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Fluorescent Dye
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CEMT is a carboxylesterase (CE) substrate and a ratiometric two-photon fluorescent reporter probe. CEMT can be hydrolyzed by CE to generate HMT, which is used for mitochondrial pH sensing. After activation by CE, CEMT exhibits ratiometric fluorescence changes in response to pH variations. CEMT targets and covalently binds to mitochondria, and can avoid leakage during acidification, thus enabling in situ imaging .
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- HY-D2949
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Fluorescent Dye
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SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
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- HY-D3188
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Fluorescent Dye
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gGlu-2OMe SiR600 is a γ-glutamyl transpeptidase (GGT) responsive fluorescent probe. gGlu-2OMe SiR600 can be converted into a highly fluorescent molecule via reaction with GGT, and its initial fluorescence is quenched through a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 exhibits fluorescence activation in malignant breast cancer and benign breast fibroadenoma tissues, enabling lesion visualization. gGlu-2OMe SiR600 can be used for research related to breast cancer and fibroadenoma .
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- HY-D3200
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Fluorescent Dye
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Dns-LLC is a cell-permeable Cu +-selective fluorescent probe that forms a 1:1 complex with Cu +. The thiol group of Dns-LLC plays a key binding role, while the sulfonamide and amide groups jointly contribute to the stabilization of the complex. Upon binding to Cu + in aqueous buffer solutions, Dns-LLC generates a turn-on fluorescence response, which can be used for the detection of Cu + in the Golgi apparatus .
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- HY-D2956
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CLIP-GLA-NHS
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Fluorescent Dye
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BC-GLA-NHS (CLIP-GLA-NHS) is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .
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- HY-D2973
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Fluorescent Dye
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YH-APN is a high-performance APN activated near-infrared fluorescent probe. YH-APN has high sensitivity, high selectivity, fast response, and can achieve extremely high tumor/normal tissue signal-to-noise ratio through in situ spraying. YH-APN can specifically distinguish cancer cells with high expression of APN from normal cells and monitor the migration of cancer cells .
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- HY-D1836
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VF 555 Tyramide
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Fluorescent Dye
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Vari Fluor 555 TSA (200x) , also know as VF 555 Tyramide. Vari Fluor 555 TSA (200x) is one of Vari Fluor TSA series fluorescent probes, which can be used for high-density in situ labeling assays. Vari Fluor TSA series target antigens via horseradish peroxidase (HRP), which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .
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- HY-203233
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Fluorescent Dye
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Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu 2+-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy .
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- HY-D3143
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Fluorescent Dye
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QM-B-CF is a sequential dual-lock chemiluminescent/fluorescent dual-mode probe designed for the specific detection of H2O2, and it can produce enhanced chemiluminescence upon photoirradiation. QM-B-CF generates chemiluminescent signals only under the conditions of H2O2 and light exposure in vitro, in cancer cells, and in tumor-bearing nude mice (Ex/Em = 514 nm/600 nm) .
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- HY-D3196
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Fluorescent Dye
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AG2 is a glucose uptake tracer and two-photon fluorescent probe. AG2 is taken up by cells via glucose-specific transport systems, rather than passive diffusion; it preferentially accumulates in cancer cells and colon cancer tissues compared with normal cells and tissues; it mainly localizes to mitochondria, with a small amount also distributed in the cytoplasm and cell membrane. AG2 can be used for colon cancer research .
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- HY-D3313
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15-Deoxy-Δ12,14-PGJ2-biotin
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Fluorescent Dye
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15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin-labled 15-Deoxy-Δ12,14-Prostaglandin J2 (HY-108568). 15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin can be used as a fluorescent probe.
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- HY-D0988A
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R-PE (concentrated solution)
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Fluorescent Dye
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R-Phycoerythrin (R-PE) (concentrated solution) is found in Heterosiphonia japonica. R-Phycoerythrin (concentrated solution) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (concentrated solution) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .
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- HY-D3187
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Fluorescent Dye
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HMRef-αMan is a substrate-based green fluorescent probe (Ex/Em=465 nm/515 nm) targeting MAN2C1 (α-mannosidase). HMRef-αMan can be specifically cleaved by MAN2C1 to generate a highly fluorescent product, which thus gets activated to produce green fluorescence in malignant breast tissues, benign lesions and living cancer cells. The signal intensity of HMRef-αMan is directly correlated with MAN2C1 activity, and it can effectively detect tiny breast cancer lesions with a diameter of less than 1 mm. When used in combination with the red-emitting γ-glutamyl transpeptidase (GGT) probe gGlu-2OMe SiR600 (HY-D3188), HMRef-αMan enables precise optical differentiation of breast tissue types via a dual-color imaging strategy. HMRef-αMan has been widely used in the research of breast diseases such as breast cancer, fibroadenoma, phyllodes tumor and various types of papilloma .
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- HY-D0988B
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R-PE ammonium sulfate precipitate
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Fluorescent Dye
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R-Phycoerythrin (R-PE) (ammonium sulfate precipitate) is found in Heterosiphonia japonica. R-Phycoerythrin (ammonium sulfate precipitate) is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin (concentrated solution) can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin (ammonium sulfate precipitate) can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex/Em = 496/578 nm) .
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- HY-114346A
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Fluorescent Dye
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ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
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- HY-D3171
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Fluorescent Dye
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AD-BChE/HClO is a dual-target two-photon fluorescent probe. AD-BChE/HClO can release 4-methylumbelliferone via butyrylcholinesterase-mediated hydrolysis of the ester bond at position 7, as well as hypochlorous acid-mediated thiocarbonyl oxidation. AD-BChE/HClO enables two-photon imaging in nerve cells and mouse brain tissues via tail vein injection. AD-BChE/HClO can be used for the research of Alzheimer's disease .
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- HY-D3220
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Fluorescent Dye
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PTO-41 is a blood-brain barrier-permeable near-infrared fluorescent probe that targets β-amyloid oligomers (Aβ Oligomers, AβOs) with a Kd of 349 nM. PTO-41 exhibits low cytotoxicity, high sensitivity to β-amyloid oligomers in in vitro phantom imaging, and can be rapidly cleared from the brain. PTO-41 is applicable to the research of Alzheimer's disease (Ex/Em = 538 nM/680 nM) .
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- HY-D3225
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Fluorescent Dye
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MD-B is a •OH Fluorescent probe with blood-brain barrier permeability. MD-B undergoes single-electron oxidation by hydroxyl radicals (•OH), which triggers fluorescence enhancement and enables in-situ imaging of •OH. MD-B allows imaging analysis of hydroxyl radicals (•OH) in the mouse brain, revealing a positive correlation between elevated •OH levels and the severity of depressive phenotypes. MD-B can be used in depression-related research .
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- HY-150086
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CF4
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Fluorescent Dye
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Copper Fluor-4 (CF4) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10 −13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission) .
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- HY-D2962
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Fluorescent Dye
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CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Aβ1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQ’s emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Aβ aggregates in Alzheimer's disease .
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- HY-D3251
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Fluorescent Dye
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LCP is a fluorescent probe applicable for subcellular localization. LCP responds to polarity changes in the cellular microenvironment via fluorescence resonance energy transfer, emitting blue fluorescence in low-polarity environments and red fluorescence in high-polarity environments. LCP enables dual-color visualization of dynamic changes in lysosomes and cytoplasmic membranes during drug-induced cell apoptosis, and monitors cell viability through localization and emission color changes. LCP can be used in cancer research .
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- HY-D3250
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Fluorescent Dye
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PYSNO is a lysosome-targeted fluorescent probe based on a pyridazinone skeleton (λem=515-565 nm, λex=405 nm) that can be used to track nitric oxide (NO) production in vivo. PYSNO exhibits a rapid, highly sensitive and highly selective "turn-on" response to endogenous and exogenous NO by blocking photoinduced electron transfer and regulating radiative decay rates. PYSNO enables precise in vivo monitoring in a mouse model of myocardial fibrosis and can be applied to the research of related diseases .
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- HY-158616
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Fluorescent Dye
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4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.
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- HY-D2992
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Fluorescent Dye
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KSA02 is a two-dimensional intelligent fluorescent probe. KSA02 not only detects the activity of the aging-related β-galactosidase (SA-β-gal), but also can simultaneously sense the pH value changes of the lysosomal microenvironment where SA-β-gal is located. KSA02 can distinguish between aging and cancer, track the aging process, and evaluate the efficacy of anti-aging agents. KSA02 can be used for the study of aging biology .
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- HY-D3172
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Fluorescent Dye
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BD-105 is a glucagon-binding fluorescent probe with a Ka value of 13.3 μM. BD-105 exhibits changes in fluorescence intensity upon interaction with glucagon, and colocalizes with glucagon in cells and tissues. BD-105 is a selective cell stain that labels glucagon-secreting cells without staining insulin-secreting cells or non-endocrine control cells. BD-105 serves as an imaging reagent for glucagon in live cells and tissues .
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- HY-D3168
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Fluorescent Dye
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PCL-2 is a reactive oxygen species-responsive fluorescent probe that shows almost no response to biologically relevant reactive oxygen species other than hydrogen peroxide. PCL-2 reacts with hydrogen peroxide to release 6-hydroxy-2-cyanobenzothiazole. PCL-2 can be used for chemoselective imaging of hydrogen peroxide in in vitro models and acute inflammation mouse models. PCL-2 is applicable to studies related to acute inflammation .
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- HY-D3189
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Fluorescent Dye
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5GluAF-2MeTG is an activatable fluorescent probe targeting the glutamate carboxypeptidase (CP) activity of PSMA (Ex/Em=490/500-600 nm). After being hydrolyzed by PSMA, 5GluAF-2MeTG releases a cell membrane-permeable fluorescent product, and achieves fluorescence activation by disrupting donor-excited photoinduced electron transfer (d-PeT). 5GluAF-2MeTG enables fluorescence imaging of live PSMA-expressing prostate cancer cells in vitro and visualizes the carboxypeptidase activity of PSMA. 5GluAF-2MeTG can be used to detect prostate cancer regions in preclinical excised tissue specimens .
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- HY-D3190
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Fluorescent Dye
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BODIPY-DOX is a conjugate composed of BODIPY and Doxorubicin (HY-15142A), as well as a pH-activated fluorescent probe for M1 macrophages and an apoptosis inducer. BODIPY-DOX undergoes pH-induced hydrazone bond cleavage in acidic M1 macrophage phagosomes, thereby releasing cytotoxic Doxorubicin (Dox) and inhibiting the function of pro-inflammatory M1 macrophages. BODIPY-DOX highly selectively inhibits the production of relevant pro-inflammatory cytokines by mouse and human monocyte-derived M1 macrophages, while exerting minimal effects on M2 or unactivated macrophages. Therefore, BODIPY-DOX enables simultaneous fluorescent tracing, differentiation and elimination of specific macrophage subsets, and exhibits the potential to regulate tissue regeneration in zebrafish models .
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- HY-D3209
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Fluorescent Dye
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NIR-ASM is a near-infrared fluorescent probe that can cross cell membranes and be activated by NQO1. NIR-ASM can distinguish NQO1-expressing cancer cells from normal cells via fluorescence microscopy and flow cytometry. NIR-ASM generates near-infrared fluorescence with a high signal-to-noise ratio in tumor models with NQO1 activity, enabling the detection of endogenous NQO1 activity in vivo. NIR-ASM is applicable to the research of lung cancer and breast cancer .
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- HY-D2982
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Fluorescent Dye
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BTP9-Neu5Ac is a fluorescent imaging probe specifically designed for detecting the neuraminidase (NA) sialidase activity of influenza viruses. BTP9-Neu5Ac can visualize the intracellular Golgi localization of the viral NA activity. BTP9-Neu5Ac can be used for precise and temporal monitoring of the key enzyme activities during the viral life cycle .
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- HY-D3224
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Fluorescent Dye
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HCP is a two-photon fluorescent probe capable of crossing the blood-brain barrier, which is specifically designed for real-time detection of hypochlorous acid (HClO/ClO -) produced by myeloperoxidase (MPO). Chlorination of the quinoline skeleton of HCP generates HCP-Cl, which eliminates intramolecular charge transfer (ICT) quenching and thereby produces fluorescence. HCP is suitable for in vivo dynamic imaging of HClO in the brains of epileptic mice and high-throughput screening of antiepileptic drugs (HCP-Cl: Ex/Em = 800 nm/495 nm) .
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- HY-D2942
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Fluorescent Dye
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BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .
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- HY-D3174
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Fluorescent Dye
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PiF is a fluorescent probe with high specificity for pancreatic β-cells (Ex/Em = 535 nm/565 nm), and its fluorescence signal increases significantly with elevated insulin concentrations in in vitro experiments. PiF enables visualization of rat and human islets transplanted via the portal vein in mouse livers with low liver background signals. The fluorine atom of PiF can be replaced by radioactive 18F to prepare a PET tracer. PiF can be used for research on type 1 diabetes .
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- HY-D3211
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Fluorescent Dye
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HJTA is a selective, pH/GSH dual-responsive Fluorescent probe and anticancer agent. HJTA selectively undergoes an enzymatic reaction with GSTπ. HJTA induces Apoptosis and Autophagy by regulating the expression of apoptotic and autophagic proteins. HJTA exhibits pH- and GSH-dual-responsive fluorescence in tumor cells. HJTA selectively illuminates tumor tissues, enabling precise in situ visualization of colon tumors. HJTA exerts anticancer effects against colon cancer. HJTA can be used for colon cancer research .
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- HY-D3269
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Fluorescent Dye
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Mito-Cu (II) is a mitochondria-targeted fluorescent probe (Ex/Em = 370/450 nM). Mito-Cu (II) specifically accumulates in mitochondria of living cells and enables real-time detection of exogenous Cu 2+ within mitochondria of living cells. Mito-Cu (II) achieves "on-off-on" fluorescence switching through sequential exposure to Cu 2+ and ethylenediaminetetraacetic acid (EDTA) (HY-Y0682). Its fluorescence is quenched after forming a 1:1 complex with Cu 2+, and the fluorescence recovers when Cu 2+ is chelated by EDTA .
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- HY-DY1104
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CF4 (solution)
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Fluorescent Dye
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Copper Fluor-4 (solution) (CF4 (solution)) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 solution has high copper selectivity with a Kd value of 2.9×10 ?13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 solution is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission) .
Solvent and concentration: DMSO: 5 mM
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- HY-D2998
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Fluorescent Dye
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ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes .
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- HY-128868B
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Fluorescent Dye
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FITC-Dextran (MW 3000-5000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 3000-5000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 3000-5000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption . Storage: protect from light.
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- HY-156404
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PM-1
2 Publications Verification
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Fluorescent Dye
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PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins .
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- HY-D2963
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Fluorescent Dye
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R-MA-SLM is an Aβ-targeted and blood-brain barrier-permeable ratiometric H2O2-responsive fluorescent probe. When excited at 490 nm, the fluorescence intensity of the R-MA-SLM gradually decreases at 574 nm, while the emission intensity gradually increases at 661 nm. R-MA-SLM can detect and exhibits a ratiometric response to Aβ-induced endogenous H2O2. R-MA-SLM can be used in the research of Alzheimer's disease .
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- HY-D2968
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Fluorescent Dye
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DCM-ONOO is a near-infrared two-photon fluorescence probe specifically designed for real-time monitoring of the dynamic fluctuations of peroxynitrite (ONOO⁻) in epilepsy models. DCM-ONOO exhibits excellent optical properties, with a single photon excitation (Ex) of 520 nm; a single photon emission (Em) of 685 nm; a two-photon excitation of 820 nm; and a Stokes shift of 165 nm. When DCM-ONOO is combined with ONOO⁻, it shifts from 460 nm to 512 nm, and only generates a significant fluorescence response to ONOO⁻. DCM-ONOO has been successfully applied to rat epilepsy models .
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- HY-D0155
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Fluorescent Dye
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Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn 2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis .
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- HY-D2365
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Fluorescent Dye
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QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
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- HY-D2907
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DBCO-Cy5; Cyanine5 dibenzocyclooctyne
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Fluorescent Dye
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Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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- HY-D2953
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CLIP-CPY
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Fluorescent Dye
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BC-CPY is a CLIP-tagged probe based on the pyridine-benzoanthrone (CPY) fluorophore (Ex/Em: 580 nm/610 nm). BC-CPY has excellent cell membrane permeability, enabling deep imaging, low phototoxicity and high signal-to-noise ratio. BC-CPY can be used for super-resolution microscopy imaging of living cells .
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- HY-D1809
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Fluorescent Dye
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Vari Fluor 405-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=405 nm/431 nm.
Product Concentration: 0.8 mg/mL
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- HY-D3195
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Fluorescent Dye
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CDr15 is a deep-red fluorescent probe (Ex=733 nm) that can selectively intercalate into and label bacterial extracellular DNA (eDNA). CDr15 exhibits extremely high specificity for biofilm imaging and cannot effectively bind to mammalian nuclear DNA. CDr15 enables real-time visualization of the microcolony structure and developmental process of three-dimensional *Pseudomonas aeruginosa* biofilms, and accurately localizes biofilm-forming regions of microorganisms in a mouse corneal infection model. With low background interference signals, CDr15 serves as an ideal diagnostic tool for research fields including bacterial biofilms and corneal infections .
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- HY-D1807
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Fluorescent Dye
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Vari Fluor 555-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=555 nm/565 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1808
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Fluorescent Dye
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Vari Fluor 488-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=490 nm/515 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1804
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Fluorescent Dye
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Vari Fluor 680-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=680 nm/701 nm.
Product Concentration: 0.8 mg/mL
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- HY-D3170
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Fluorescent Dye
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C-HBrO-GGT is a sequence-activated two-photon fluorescent probe. C-HBrO-GGT exhibits sequential fluorescence activation properties: it generates fluorescence in response to hypobromous acid only after being hydrolytically activated by γ-glutamyl transpeptidase. C-HBrO-GGT enables verification of the voltage-gated chloride channel (CLC-1)-HBrO-catalase (CAT)-GGT signaling pathway at the cellular level. C-HBrO-GGT can serve as a tool to indicate the precise location of mature atherosclerotic plaques and provide early warning of plaque formation. C-HBrO-GGT is applicable to relevant research on atherosclerosis .
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- HY-D3415
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Fluorescent Dye
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TOR-G4 is a Fluorescent probe that binds to G-quadruplex (G4) nucleic acid structures. TOR-G4 exhibits a unique fluorescence lifetime when bound to G4 compared to other structures, enabling sensitive discrimination between G4-bound and non-G4-bound states. TOR-G4 mainly colocalizes with RNA in the cytoplasm and nucleolus. TOR-G4 can be used to investigate the roles of RNA G4 in cells. TOR-G4 shows cytotoxicity against osteosarcoma cells .
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- HY-D1805
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Fluorescent Dye
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Vari Fluor 647-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=650 nm/665 nm.
Product Concentration: 0.8 mg/mL
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- HY-D1806
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Fluorescent Dye
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Vari Fluor 594-Streptavidin is a dye marker of Vari Fluor-streptavidin consisting of labeling streptavidin with a Vari Fluor series of fluorescent probes. Streptavidin is a high-affinity tetramer protein, each tetramer consisting of four identical streptavidin subunits. Streptavidin binds to biotin specifically via a reversible non-covalent effect. Streptavidin can achieve rapid and efficient detection of biotin markers, and is often used in immunofluorescence (IF), enzyme-linked immunosorbent assay (ELISA), immunohistochemical staining (IFH), in situ hybridization (ISH) and other experiments. Ex/Em=590 nm/617 nm.
Product Concentration: 0.8 mg/mL
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- HY-D2924
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Fluorescent Dye
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CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .
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- HY-DY1003
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Fluorescent Dye
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JC-1 (CBIC2) (solution) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm) ; When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
Solvent and concentration: DMSO: 1.5 mM
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- HY-D3179
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Fluorescent Dye
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CDg13 is a fluorescent probe that specifically detects living neural stem/progenitor cells. CDg13 localizes to the endoplasmic reticulum via its dihexyl moiety, with no interaction with endoplasmic reticulum biomolecules. CDg13 undergoes selective efflux by active ABCG2 transporters, with increased intracellular accumulation following ABCG2 inhibition or knockdown. CDg13 isolates and enriches self-renewable neural stem/progenitor cells from embryonic mouse brain tissue, stains neural stem/progenitor cells brightly, and sorts ABCG2low cell populations from heterogeneous populations . (Ex/Em = 520/553 nm)
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- HY-D3192
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Fluorescent Dye
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CDy11 is a fluorescent probe and amyloid-binding dye (λex=590 nm; λem=612 nm), with a Ka of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .
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- HY-D1078
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Fluorescent Dye
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5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC4 for MRP2 binding sites and inhibits MRP2-mediated LTC4 transport (Ex/Em = 496/525 nm) .
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- HY-148958
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Fluorescent Dye
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SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .
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- HY-D3191
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Fluorescent Dye
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L&M-D-MR is a highly specific fluorescent "AND" logic probe with response moieties for leucine aminopeptidase (LAP) and monoamine oxidase (MAO). The coexistence of both LAP and MAO is required for L&M-D-MR to trigger intramolecular cyclization, release fluorophores and activate fluorescence. In the presence of only a single enzyme, L&M-D-MR generates only an extremely weak signal. L&M-D-MR enables bioimaging in living cells and mouse models, and can effectively distinguish different subtypes of liver diseases via blood samples or test strips. L&M-D-MR is widely used in studies related to liver cirrhosis, hepatitis B and drug-induced liver injury .
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- HY-D3181
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Fluorescent Dye
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CyGbPF is a granzyme B-specific near-infrared fluorescent probe. CyGbPF can be cleaved by granzyme B to remove the peptide cage group, restoring near-infrared fluorescence. CyGbPF passively accumulates in mouse tumors, and its activated fluorescence correlates with granzyme B expression, CD8 + cytotoxic T lymphocyte populations, and CD4 + helper T lymphocyte populations in tumor tissues. CyGbPF is efficiently cleared by the kidneys, enabling the assessment of immune activation via optical urine analysis. CyGbPF allows real-time non-invasive evaluation of cancer immunotherapeutic efficacy in living animals. CyGbPF can be used in research on cancers such as breast cancer. Excitation wavelength/emission wavelength: approximately 658 nm/approximately 717 nm .
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- HY-D3153
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Fluorescent Dye
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PbQ is a tubulin inhibitor (with an IC50 of 5 μM against goat tubulin) and a fluorescent probe for cuprous ions Cu (I). PbQ can penetrate the membrane of peripheral blood mononuclear cells, form a stable 1:1 complex with Cu + ions, and exhibits low toxicity and good biocompatibility toward macrophage cell lines. In addition, PbQ promotes tubulin degradation and disrupts the microtubule network in lung epithelial cells without affecting actin. PbQ also possesses genotoxicity by forming DNA base adducts, and it can activate caspase-3 and apoptosis-related genes, induce loss of mitochondrial membrane potential, and trigger cell apoptosis. PbQ can be used in studies related to chronic obstructive pulmonary disease .
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- HY-15558
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bisBenzimide H 33258; H 33258
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Fluorescent Dye
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Hoechst 33258 is a blue to blue-green fluorescent live cell dye that can label DNA. Hoechst 33258 can specifically bind to the minor groove of DNA (and tends to bind to A/T-rich DNA), resulting in a significant increase in fluorescence intensity. Hoechst 33258 can cross the cell membrane and cause changes in DNA structure, such as G2/M phase arrest. Hoechst 33258 can bind to live or fixed cells, and the fluorescence intensity increases with increasing solution pH. As a DNA-specific probe, Hoechst 33258 can be used to detect DNA content, analyze cell cycle, etc. The excitation wavelength of Hoechst 33258 is 350-365 nm, and the emission wavelength is 460-490 nm .
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- HY-D3186
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Fluorescent Dye
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HMRef-βGal is a fluorescent probe and a substrate responsive to β-galactosidase (β-galactosidase) (Ex/Em=498 nm/505-600 nm). After being cleaved by β-galactosidase, HMRef-βGal triggers significant fluorescence enhancement via intramolecular spirocyclic function regulation. HMRef-βGal generates bright fluorescence in cancer cells with elevated β-galactosidase activity, enabling visualization of tiny peritoneal metastases in mouse models. HMRef-βGal exhibits low in vitro cytotoxicity and low acute in vivo toxicity in mice. HMRef-βGal can be used for preclinical fluorescence-guided diagnosis and cytoreductive surgery of peritoneal metastases, including compatibility with real-time naked-eye detection and endoscopic imaging, as well as for studies related to peritoneal metastases of ovarian cancer .
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- HY-D3210
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Fluorescent Dye
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DCM-KPV is a fluorescent probe targeting the human intestinal oligopeptide transporter PEPT1/SLC15A1 receptor (λex=480 nm, λem=620-670 nm). DCM-KPV specifically binds to PepT1 via its KPV domain and mediates receptor-targeted internalization, thus effectively accumulating in the cytoplasm and nucleus of cells overexpressing this receptor. DCM-KPV has the advantages of long emission wavelength, high emission efficiency, low photobleaching, and negligible cytotoxicity. DCM-KPV maintains stable fluorescence intensity under continuous illumination, exhibiting extremely high live cell compatibility. DCM-KPV can specifically accumulate at colonic inflammatory sites through the intestinal mucosa, enabling direct non-invasive visual differentiation between chronic and acute ulcerative colitis groups and the normal group .
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- HY-D1269
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Fluorescent Dye
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Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups . Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm).
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- HY-151701
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Fluorescent Dye
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DiSulfo-Cy5 alkyne is a fluorescent dye can be used as a click chemistry reagent .
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- HY-133424A
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Fluorescent Dye
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Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
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- HY-113053F
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PGA1-biotin
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Fluorescent Dye
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Prostaglandin A1-biotin (PGA1-biotin) is a biotin-labeled Prostaglandin A1 (HY-113053). Prostaglandin A1-biotin can be found in the culture filtrate of rhizobia, and the culture filtrate containing this compound exhibits significant antiviral activity .
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- HY-D1029A
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Fluorescent Dye
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Biotin-11-dUTP trisodium is a fluorescent substitute for dTTP.
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- HY-D2593
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Fluorescent Dye
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Cy7.5-PEG2000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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- HY-D1030
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Fluorescent Dye
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Fluorescein Biotin is a fluorescent modulator with avidin and streptavidin binding activity. Fluorescein Biotin binds to the biotin-binding sites of avidin and streptavidin, and this binding induces significant fluorescence quenching .
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- HY-D2025
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Fluorescent Dye
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ATTO 550 biotin is a biotin derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
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- HY-D1925
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Fluorescent Dye
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ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
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- HY-D1361
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Fluorescent Dye
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Alkyne cyanine dye 718 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2852
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Fluorescent Dye
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Heparin-Cy7 is a fluorescent dye composed of CY7 (HY-D0825) and heparin. Heparin-CY7 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 740/770 nm).
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- HY-D0226R
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1,4-Dihydroxyanthraquinone (Standard)
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Fluorescent Dye
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Quinizarin (Standard) is the analytical standard of Quinizarin. This product is intended for research and analytical applications. Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .
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- HY-W998662
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Fluorescent Dye
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Coumarin 343 X carboxylic acid is a blue emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).
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- HY-D1027
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Monodansyl cadaverine
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Fluorescent Dye
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Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
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- HY-D2661
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Fluorescent Dye
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Cy5.5 HA (MW 100000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-155324
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Fluorescent Dye
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Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-D2191
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- HY-D2342
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Fluorescent Dye
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SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells .
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- HY-W800809
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Fluorescent Dye
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FAM DBCO, 6-isomer represents a variant of a time-honored fluorescent dye and featuring a terminal DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy.
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- HY-D1485
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Fluorescent Dye
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3,3'-Diethylthiacyanine iodide is a cyanine fluorescent dye. 3,3'-Diethylthiacyanine iodide manifestes a pronounced affinity for bacterial cells .
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- HY-D2537
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Fluorescent Dye
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Cy3-PEG2000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-100041
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Monobromobimane
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Fluorescent Dye
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Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
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- HY-137296
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Fluorescent Dye
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Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .
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- HY-D1683A
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Fluorescent Dye
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NBD-X PE is a derivative of NBD-PE, where the NBD part is replaced by NBD-X acid.
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- HY-D2758
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Fluorescent Dye
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TAMRA DBCO, 5-isomer is a derivative of tetramethylrhodamine (TMR, TAMRA) containing a cyclooctyne moiety (dibenzocyclooctyne, DBCO). Pure 5-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction (SPAAC)). TAMRA DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups.
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- HY-138111
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p-Nitopheyl β-D-cellotetaoside
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Fluorescent Dye
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4-Nitrophenyl β-D-cellotetraoside (p-Nitopheyl β-D-cellotetaoside) is a small molecule cellulose mimetic consisting of a tetramer of D-glucose units linked by β-1-4 glycosidic bonds. The fragmentation pattern of 4-Nitrophenyl β-D-cellotetraoside after enzymatic hydrolysis can be analyzed by TLC or by the release of 4-nitrophenol, which has a strong absorbance at 395 nm in alkaline solutions. 4-Nitrophenyl β-D-cellotetraoside can be used in cellulose degradation studies to determine the specificity of cellulases .
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- HY-137844
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Leu-AMC hydrochloride
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Fluorescent Dye
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L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .
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- HY-W273413
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NBD-H
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Fluorescent Dye
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4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is a fluorescent reagent used for protein labeling .
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- HY-D2169
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Fluorescent Dye
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AF 568 carboxylic acid is the non-reactive form of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne forms stable covalent bonds by reacting carboxylic acid groups with molecules bearing amino groups. Copper-catalyzed azide-alkyne cycloaddition (CuAAc) can occur with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups .
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- HY-D2284
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Sphingosine-1-phosphate lyase fluorogenic substrate
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Fluorescent Dye
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SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .
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- HY-D1916A
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Fluorescent Dye
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ATTO 594 TEA is a highly hydrophilic fluorescent dye used to label the outermost position of the glycan moiety of glycosphingolipids to retain the biophysical and biochemical properties of native glycosphingolipids .
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- HY-15937
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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers
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Fluorescent Dye
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5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.
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- HY-D2105
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Fluorescent Dye
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TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2371
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Fluorescent Dye
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3-BTMD is obtained by COMT enzyme specifically catalyzing the substrate 3-BTD (Ex=390 nm, Em=510 nm) .
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- HY-B1533A
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Fluorescent Dye
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Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λmax = 571 nm .
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- HY-136248A
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Fluorescent Dye
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Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
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- HY-D2838
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Fluorescent Dye
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mPEG-PEI-Cy5 (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 5000) can be used for fluorescent labeling and imaging .
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- HY-D1983
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Fluorescent Dye
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ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
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- HY-D1700
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Fluorescent Dye
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Mag-indo-1/AM is a cell-permeable fluorescent indicator for Mg 2+ and also for Ca 2+ (Ex=340-390 nm, Em=410-490 nm). Mag-indo-1/AM can be used to determine intracellular Mg 2+ and Ca 2+ concentrations .
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- HY-121930
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Fluorescent Dye
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Coumarin 6H, a Coumarin (HY-N0709) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions .
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- HY-D2642
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Fluorescent Dye
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Cy5 HA (MW 10000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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- HY-136937
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Fluorescent Dye
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PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-112803
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Fluorescent Dye
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GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2).
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- HY-D1260
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PSH-red
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Fluorescent Dye
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FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .
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- HY-D2911
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Fluorescent Dye
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Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
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- HY-D2575
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Fluorescent Dye
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WYneN (compound 10) is a functionalized Wittig-alkyne probe. WYneN exhibits strong reactivity with sulfinic acid dipeptide models, similar to the parent Wittig reagent. WYneN can be used to reveal the function of oxidative modifications on a proteome-wide scale .
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- HY-D2034
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Fluorescent Dye
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ATTO 514 hydrazid is a hydrazide derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
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- HY-D1317A
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Fluorescent Dye
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Cyanine7.5 carboxylic is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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- HY-D1040
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Cyanine 5.5 carboxylic acid
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Fluorescent Dye
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Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis .
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- HY-DY1017
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Fluorescent Dye
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Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718) , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
Solvent and concentration: DMSO: 5 mg/mL
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- HY-DY1060
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Fluorescent Dye
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Suc-Leu-Leu-Val-Tyr-AMC (solution) is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
Solvent and concentration: DMSO: 20 mM
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- HY-D2007
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Fluorescent Dye
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ATTO 488 biotin is a biotin derivative of ATTO 488 with maximum excitation/emission wavelengths: 500/520 nm.
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- HY-B0315A
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Biotin-Cyanocobalamin B12
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Fluorescent Dye
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Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is the biotinylated Vitamin B12 (HY-B0315). Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. Biotin-Vitamin B12 can be used in researches on vitamin B12 transport, cellular uptake, targeted delivery, analytical detection, and other areas .
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- HY-D1456
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Fluorescent Dye
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TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .
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- HY-121426
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- HY-D2615
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Fluorescent Dye
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ICG PEG5000 biotin is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em=785/813 nm).
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- HY-77962
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Fluorescent Dye
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2-Thiobarbituric acid is a commonly used colorimetric reagent for the detection of malondialdehyde (MDA), a marker of lipid peroxidation. 2-Thiobarbituric acid forms a complex with MDA that can be quantified by colorimetric detection at 532 nm as a measure of lipid peroxidation .
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- HY-D1548
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Fluorescent Dye
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1-(Azidomethyl)pyrene is a fluorescent dye . 1-(Azidomethyl)pyrene is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-101888R
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Fluorescent Dye
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Cresyl Violet acetate (Standard) is the analytical standard of Cresyl Violet acetate (HY-101888). This product is intended for research and analytical applications. Cresyl Violet acetate is a dye, which can be used to stain neurons.
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- HY-D2561
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Fluorescent Dye
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Cy5.5-PEG3400-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-111391R
-
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Diazoresorcinol sodium (Standard)
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Fluorescent Dye
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Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.
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- HY-D1375
-
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Fluorescent Dye
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Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1307A
-
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Fluorescent Dye
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Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
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- HY-D2589
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Fluorescent Dye
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|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
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- HY-D0028
-
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Fluorescent Dye
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|
6-(4-Acetamido-1,8-naphthalamido)hexanoic acid is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-W440303
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HITC
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Fluorescent Dye
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1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate (HITC) is a long-wavelength, membrane-potential sensitive dye. It is a slow-response potentiometric fluorophore and has also been used as a laser dye for infrared lasers.
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- HY-D2139
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Fluorescent Dye
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Cy3-PEG3-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2699
-
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|
Fluorescent Dye
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|
Cy7.5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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- HY-D2259
-
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Fluorescent Dye
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|
PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation .
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- HY-D2845C
-
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Fluorescent Dye
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|
4-arm-PEG20000-FITC is a fluorescent dye composed of FITC (HY-66019) and four-arm polyethylene glycol (4-Arm PEG). 4-arm-PEG20000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
- HY-D2527
-
|
|
Fluorescent Dye
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|
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated PEG4-amide-PEG2-C6-Cl.
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- HY-DY1071
-
|
|
Fluorescent Dye
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pH Receptor Probe (solution) is a pH-sensitive cyanine derivative and a environmental sensitive fluorophore. pH Receptor Probe has a pH-sensitive maximal absorption at 644 nm and emission at 664 nm. pH Receptor Probe has been used as a pH sensor of lysosomal compartments .
Solvent and concentration: DMSO: 10 mM
|
- HY-D2078
-
|
|
Fluorescent Dye
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|
ATTO 665 amine is an amine derivative of ATTO 665, the maximum excitation/emission wavelength: 663/680 nm.
|
- HY-W351339
-
|
|
Fluorescent Dye
|
|
BAPTA-TMFM is a fluorescent chelating indicator used to study the role of cytosolic free calcium.
|
- HY-B1025R
-
|
Lanadigenin (Standard)
|
Fluorescent Dye
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|
Digoxigenin (Standard) is the analytical standard of Digoxigenin. This product is intended for research and analytical applications. Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .
|
- HY-D1675
-
|
|
Fluorescent Dye
|
|
6-HoeHESIR is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2505
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|
Fluorescent Dye
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|
Cy3-PEG1000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG1000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
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- HY-D2182
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Fluorescent Dye
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|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
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- HY-D1639
-
|
|
Fluorescent Dye
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|
5,5'-Dibromo BAPTA tetrapotassium is a calcium chelator, can be formulated into a buffer with a defined calcium ion concentration. 5,5'-Dibromo BAPTA tetrapotassium can control the concentration of calcium ions inside and outside the cell and can be used in studies of calcium physiological activity .
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- HY-D2104
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Fluorescent Dye
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|
TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
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- HY-DY1051
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|
Fluorescent Dye
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Resazurin sodium (Diazoresorcinol sodium) (solution) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
Solvent and Concentration: Sterile water: 10 mM
|
- HY-101880R
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10-Acetyl-3,7-dihydroxyphenoxazine (Standard)
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Fluorescent Dye
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|
ADHP (Standard) is the analytical standard of ADHP (HY-101880). This product is intended for research and analytical applications. ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
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- HY-D1622
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Cy3-DBCO hexafluorophosphate
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Fluorescent Dye
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|
Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
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- HY-D1860
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|
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Fluorescent Dye
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|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-120959
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|
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Fluorescent Dye
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|
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
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- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dye
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|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
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- HY-D2706
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|
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Fluorescent Dye
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|
Cy3 Dextran (MW 3000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-D2177
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|
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Fluorescent Dye
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|
AF 555 azide is a fluorescent dye and is the azide of AF 555. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 555/565 nm) .
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- HY-141576
-
|
dhCerC6NBD
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Fluorescent Dye
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|
C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .
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- HY-158739
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Fluorescent Dye
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|
Rhodamine dithenoyl hydrazide (probe 1) possesses excellent recognition and selectivity for Fe 3+ ion. Rhodamine dithenoyl hydrazide exhibits Excitation/Emission maxima of 543/550-700 nm, respectively .
|
- HY-W040230
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Fluorescent Dye
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|
Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys 34 .
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- HY-D2771
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|
|
Fluorescent Dye
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|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
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- HY-D1890
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|
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Fluorescent Dye
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|
N-(2-Aminooxyethyl)-7-DCCAm (Compound 7) is a fluorescent dye, and can be used for protein labeling .
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- HY-D1950
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|
Fluorescent Dye
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|
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .
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- HY-D1524A
-
|
1,8-EDNAS sodium
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Fluorescent Dye
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|
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2186
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|
|
Fluorescent Dye
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|
BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material .
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- HY-135414B
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|
|
Fluorescent Dye
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-151757
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|
|
Fluorescent Dye
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|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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- HY-112624F
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|
|
Fluorescent Dye
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|
CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
|
- HY-DY1005
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|
|
Fluorescent Dye
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Hoechst 33342 trihydrochloride (solution) is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .
Solvent and Concentration: Sterile water: 10 mg/mL
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- HY-D2155
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|
|
Fluorescent Dye
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|
Texas red-X 4-succinimidyl ester is a derivative of Texas Red (HY-101878), an amphoteric rhodamine red fluorescent dye. Texas Red is widely used to study neuronal morphology and as a cell type-selective fluorescent marker for astrocytes, both in vivo and in slice preparations.
|
- HY-D1309
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|
Fluorescent Dye
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
- HY-D1779
-
|
|
Fluorescent Dye
|
|
Fura-5F pentapotassium is a cell-impermeant fluorescent calcium indicator.
|
- HY-D2630
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|
|
Fluorescent Dye
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|
Cy3 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
- HY-D2704
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA biotin (MW 10000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
|
- HY-D2480
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|
|
Fluorescent Dye
|
|
BODIPY 480/508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of Cholesteryl Linoleate (HY-W010697). BODIPY 480/508-cholesteryl linoleate has been used to monitor cholesterol trafficking in isolated human monocyte-derived macrophages (Ex/Em=480/508 nm).
|
- HY-P2628
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|
|
Fluorescent Dye
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|
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K + deprivation-induced apoptosis of cerebellar granule neurons .
|
- HY-D0102
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|
ABD-F
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Fluorescent Dye
|
|
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols (Ex/Em: 380/510 nm). 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor .
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- HY-D2752
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|
|
Fluorescent Dye
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|
Cy5.5 dimethyl is a free non-activated dye and can be used as a non-reactive fluorophore for experiment controls and instrument calibration. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.
|
- HY-129953F
-
|
PGF2α-biotin
|
Fluorescent Dye
|
|
Prostaglandin F2α-biotin (PGF2α-biotin) is a biotinylated form of Prostaglandin F2α (HY-12956). Prostaglandin F2α-biotin can be used in the study of the mechanism of action of prostaglandins. In addition, Prostaglandin F2α-biotin can be detected in the ethanolic extract of Hawm Gra Dang Ngah rice .
|
- HY-D2919
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|
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Fluorescent Dye
|
|
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .
|
- HY-D0259R
-
|
Erythrosin extra bluish (Standard)
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Fluorescent Dye
|
|
Erythrosine B (Standard) is the analytical standard of Erythrosine B. This product is intended for research and analytical applications. Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
|
- HY-D2567
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|
|
Fluorescent Dye
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|
Cy5.5-PEG5000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D1451
-
|
|
Fluorescent Dye
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|
PKH 26 is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm), which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies .
|
- HY-D2150
-
|
|
Fluorescent Dye
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
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- HY-D1619
-
|
|
Fluorescent Dye
|
|
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination .
|
- HY-D1556
-
|
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium
|
Fluorescent Dye
|
|
18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .
|
- HY-D1382
-
|
|
Fluorescent Dye
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|
BrIR2 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-DY1085
-
|
5(6)-Carboxytetramethylrhodamine (solution)
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Fluorescent Dye
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5(6)-TAMRA (solution) (5(6)-Carboxytetramethylrhodamine (solution)) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D2639
-
|
|
Fluorescent Dye
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|
TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .
|
- HY-D1435
-
|
|
Fluorescent Dye
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|
Oxonol VI is an optical indicator of membrane potential in lipid vesicles (excitation/emission wavelengths: 614/646 nm). Oxonol VI can be used to detect changes in membrane potential associated with (Na + + K +)-ATPase activity in reconstituted vesicles .
|
- HY-162160
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|
|
Fluorescent Dye
|
|
NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes .
|
- HY-D2230
-
|
|
Fluorescent Dye
|
|
Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
|
- HY-162051
-
|
|
Fluorescent Dye
|
|
CYP1B1-IN-6 (compound 19) is a fluorescence molecular probes which inhibits CYP1B1 activity. CYP1B1-IN-6 can identify tumor sites in fluorescence imaging and photoacoustic imaging modes .
|
- HY-D2817A
-
- HY-D2510
-
|
|
Fluorescent Dye
|
|
Cy3-PEG2000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG2000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
|
- HY-W040209
-
|
α-NPO
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Fluorescent Dye
|
|
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .
|
- HY-D1434
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|
|
Fluorescent Dye
|
|
FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
|
- HY-D1621
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|
|
Fluorescent Dye
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|
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .
|
- HY-135641
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|
|
Fluorescent Dye
|
|
Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
|
- HY-123533
-
|
NSC 12097
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Fluorescent Dye
|
|
Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte .
|
- HY-D2526
-
|
|
Fluorescent Dye
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|
Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
- HY-D1536
-
|
|
Fluorescent Dye
|
|
Glycine cresol red is a complexometric indicator. Glycine cresol red forms coloured complexes with Al 3+, Ga 3+ and In 3+ ions in aqueous solutions. Glycine cresol red can been used for the spectrophotometric determination of inorganic ions. Glycine cresol red can be used as a stain in neurohistology .
|
- HY-D2530
-
|
|
Fluorescent Dye
|
|
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2588
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|
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Fluorescent Dye
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Cy7.5 PEG-NH2 is a polyethylene glycol derivative containing CY7.5 (HY-D0926) fluorescent dye and polyethylene glycol (PEG) and an amino group. The CY7.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy7.5 PEG-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
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- HY-W154295
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Fluorescent Dye
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Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity .
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- HY-D2556
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Fluorescent Dye
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Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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- HY-D0068
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7-Diethylaminocoumarin-3-carboxylic acid, SE
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Fluorescent Dye
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DEAC, SE (7-Diethylaminocoumarin-3-carboxylic acid, SE) is an excellent blue fluorescent building block for labeling amine-containing biomolecules.
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- HY-D1882
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Fluorescent Dye
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Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .
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- HY-W035138
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Fluorescent Dye
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Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins .
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- HY-D2733
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Fluorescent Dye
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N14G is a fluorescent dye that can be used to stain bacteria such as Mycobacterium tuberculosis .
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- HY-D1757
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LYen; PAsp- LY
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Fluorescent Dye
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Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
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- HY-D2868
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4',6-Diamidino-2-phenylindole
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Fluorescent Dye
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DAPI (4',6-Diamidino-2-phenylindole) is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
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- HY-DY3003
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Fluorescent Dye
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Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is mainly composed of paraformaldehyde, phosphate, and deionized water, with a pH of 7.0-7.4. Tissue and Cell Fixative (4% Paraformaldehyde, PFA) is suitable for fixing most tissues and cells, and can effectively protect the morphology and structure of tissues and cells as well as nucleic acids.
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- HY-D2596
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Fluorescent Dye
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Cy7.5-PEG10000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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- HY-D2217
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Fluorescent Dye
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Cy7 tetrazine is a near infrared dye that can be used for in vivo imaging .
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- HY-110393
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Fluorescent Dye
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CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound .
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- HY-D0115
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Fluorescent Dye
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7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .
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- HY-101878R
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Sulforhodamine 101 (Standard); SR101 (Standard)
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Fluorescent Dye
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Texas Red (Standard) is the analytical standard of Texas Red (HY-101878). This product is intended for research and analytical applications. Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
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- HY-D1891
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Fluorescent Dye
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6-HEX, SE is a derivative of 6-HEX that is widely used in nucleic acid sequencing .
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- HY-D1970
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Fluorescent Dye
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ATTO 700 Cadaverin is a cadaverine derivative of ATTO 700 for reactions of carboxylic acids, aldehydes and ketones with maximum excitation/emission wavelengths: 700/716 nm.
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- HY-D1886
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Fluorescent Dye
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Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.
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- HY-DY1055
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Fluorescent Dye
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TSQ (solution) is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence (Ex/Em = 334/495 nm) .
Solvent and concentration: DMSO: 10 mM
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- HY-D2746
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Fluorescent Dye
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Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
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- HY-D0023
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HPTS; Solvent Green 7
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Fluorescent Dye
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Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu + ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .
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- HY-D2348A
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Fluorescent Dye
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ACE TFA is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE TFA enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .
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- HY-D1689
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Fluorescent Dye
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Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm) .
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- HY-D2219
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Fluorescent Dye
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Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
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- HY-138147
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Fluorescent Dye
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DCP-Rho1 is a rhodamine-labeled probe. DCP-Rho1 can be used for the detection of sulfenic acid-containing proteins. DCP-Rho1 shows λex of 560 nM, λem, 581 nm .
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- HY-D1704
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Fluorescent Dye
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Bodipy TMR-X muscimol is a Bodipy labeled Muscimol (HY-N2313) (Ex=543 nm, Em=572 nm). Muscimol is a GABAA agonist. Bodipy TMR-X muscimol can be used for imaging the spread of reversible brain inactivations .
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- HY-DY1059
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Fluorescent Dye
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FM1-43 (solution) is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
Solvent and concentration: DMSO: 10 mM
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- HY-D1423
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Fluorescent Dye
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Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .
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- HY-D2601
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Fluorescent Dye
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ICG PEG3400 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG3400 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
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- HY-DY1090
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Fluorescent Dye
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BODIPY 493/503 methyl bromide (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
Solvent and concentration: DMSO: 5 mM
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- HY-D2295
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Fluorescent Dye
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Mito-FerroGreen is a mitochondria-specific ferrous ion detection probe with an excitation wavelength of 488nm .
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- HY-131028
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JF646 TFA
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Fluorescent Dye
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Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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- HY-D1579
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Fluorescent Dye
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C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .
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- HY-133852
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FD-1080
1 Publications Verification
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Fluorescent Dye
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FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
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- HY-W247103
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Fluorescent Dye
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Rhodamine 19 perchlorate is a metal free organic dye for dye sensitized solar cells.
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- HY-W923645
-
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Diacryloyloxyfluorescein
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Fluorescent Dye
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Fluorescein O,O′-diacrylate (Diacryloyloxyfluorescein) is a fluorescent compound with good biocompatibility and cell labeling ability. Fluorescein O,O′-diacrylate is often used in biological imaging and cell tracking research, and can effectively label cells and track their dynamic changes in vivo. Fluorescein O,O′-diacrylate is also used in compound delivery systems to improve the localization accuracy and inhibitory effect of compounds. Fluorescein O,O′-diacrylate is also used to prepare polymer materials to enhance their optical properties and biological interactions.
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- HY-D1416
-
HMBR
1 Publications Verification
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Fluorescent Dye
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HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .
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- HY-126821A
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Fluorescent Dye
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Fluo-3 pentaammonium is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 pentaammonium itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
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- HY-D2844C
-
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Fluorescent Dye
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FITC-PEG3400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG3400-FA can be used for fluorescent labeling and imaging .
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- HY-W879228
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Fluorescent Dye
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Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
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- HY-D1690
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Fluorescent Dye
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sBADA TFA is a potent green fluorescent dye. sBADA TFA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA TFA is used to label peptidoglycans in bacterial cell walls in situ. (λex=490 nm, λem=510 nm) .
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- HY-D1354
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Fluorescent Dye
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Azide MegaStokes dye 673 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-15938
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Fluorescent Dye
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5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .
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- HY-151756
-
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Fluorescent Dye
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diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .
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- HY-D2902
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Fluorescent Dye
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SNOTRAP (S-nitrosylation trapping by triaryl phosphine) is a chemical probe for S-nitrosylated (SNO) proteins. SNOTRAP based proteomic pipeline can identify 1181 SNO proteins (1714 SNO sites) in the brain of mouse models. SNOTRAP can be used for nitrosative stress related diseases such as neurodegenerative disease, endotoxic shock, cancer, multiple sclerosis, and sickle cell disease .
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- HY-D2038
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Fluorescent Dye
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ATTO 550 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 alkyne is an alkyne derivative of ATTO 550 and can be used to label proteins or antibodies.
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- HY-D1045A
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DABCYL sodium; Para-methyl red sodium
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Fluorescent Dye
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Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
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- HY-P3362
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Fluorescent Dye
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Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
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- HY-D2566
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Fluorescent Dye
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Cy5.5-PEG3400-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D1305
-
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Fluorescent Dye
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ATTO 488 carboxylic acid is a new fluorescent label based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 carboxylic acid is a carboxylic acid derivative of ATTO 488, which can be used to label proteins or antibodies.
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- HY-D2844E
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Fluorescent Dye
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FITC-PEG10000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG10000-FA can be used for fluorescent labeling and imaging .
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- HY-D2487
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Fluorescent Dye
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Sulfo Cy5 bis COOH is a derivative of Cy5 (HY-D0821) dye containing sulfonate ions. Sulfo Cy5 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-D2835
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Fluorescent Dye
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mPEG-PEI-Cy5 (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 1000) can be used for fluorescent labeling and imaging .
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- HY-D2565
-
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Fluorescent Dye
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Cy5.5-PEG2000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2066
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Fluorescent Dye
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ATTO 680 amine is an amine derivative of ATTO 680, the maximum excitation/emission wavelength: 681/698 nm.
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- HY-D2557
-
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Fluorescent Dye
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Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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- HY-D2488
-
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Fluorescent Dye
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Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
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- HY-D2195
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Fluorescent Dye
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AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
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- HY-D1975
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Fluorescent Dye
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ATTO 725 Carboxy is a carboxyl derivative of ATTO 725, the maximum excitation/emission wavelength is: 728/751 nm.
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- HY-D2794B
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Fluorescent Dye
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FITC-PEG5000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG5000-NH2 can be used for fluorescent labeling and imaging .
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- HY-106594BR
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Pigment blue 27 (Standard)
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Fluorescent Dye
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Prussian blue soluble (Standard) is the analytical standard of Prussian blue soluble (HY-106594B). This product is intended for research and analytical applications. Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
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- HY-130575
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Fluorescent Dye
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Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.
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- HY-W840196
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Fluorescent Dye
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Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
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- HY-D0802
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Biotin N-hydroxysuccinimide ester; NHS-Biotin
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Fluorescent Dye
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Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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- HY-D2800
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Fluorescent Dye
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FITC-PEG400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG400-MAL can be used for fluorescent labeling and imaging .
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- HY-D1692
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Fluorescent Dye
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BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
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- HY-P1363F3
-
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5-FAM-Amyloid β-peptide (1-42) (human) Tris
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Fluorescent Dye
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5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
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- HY-D2433
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Fluorescent Dye
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Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
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- HY-W247131
-
DASPEI
2 Publications Verification
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Fluorescent Dye
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DASPEI is a cationic styrenyl mitochondrial dye with large Stokes shift. DASPEI has excitation and emission wavelength at 550/573 nm, which has good light chromogenic property. DASPEI can stain mitochondria in living cells with good labeling property. And DASPEI can also be used to stain presynaptic nerve endings independently of neuronal activity .
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- HY-D2057
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Fluorescent Dye
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ATTO 700 carboxy is a carboxyl derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm.
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- HY-D2840E
-
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Fluorescent Dye
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FITC-mPEG5000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG5000 can be used for fluorescent labeling and imaging .
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- HY-111956B
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Fluorescent Dye
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D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
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- HY-DY1056
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Fluorescent Dye
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Texas Red (Sulforhodamine 101) (solution) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D2439
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Fluorescent Dye
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RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
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- HY-D0082
-
- HY-DY1028
-
|
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Fluorescent Dye
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Fluo-4 AM (solution) is a cell-permeable Ca 2+ (calcium ion) indicator (Ex/Em = 485/526 nm) .
Solvent and concentration: DMSO: 1 mM
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- HY-D2247
-
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Fluorescent Dye
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ICG-CBT is a mixture of Indocyanine Green (ICG) and Cetyltrimethylammonium Bromide (CBT). ICG-CBT can be applied to both in vivo and in vitro to observe the structure and function of cells or tissues.
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- HY-D1947
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Fluorescent Dye
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ATTO 700 Streptavidin is a streptavidin derivative of ATTO 700, it can label protein or antibody, the maximum excitation/emission wavelength: 700/716 nm.
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- HY-D0313
-
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Fluorescent Dye
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Ethyl 8'-apo-caroten-8'-oate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-W879008
-
- HY-D0056
-
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Fluorescent Dye
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5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .
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- HY-149182
-
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Fluorescent Dye
|
|
Lucifer yellow iodoacetamide dipotassium is a thiol-reactive fluorescent tracer.
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- HY-D1424
-
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Fluorescent Dye
|
|
Coelenterazine hcp is a Coelenterazine analogue. Coelenterazine hcp shows high sensitivity to Ca 2+. Coelenterazine hcp is suited for monitoring intracellular Ca 2+ .
|
- HY-137896
-
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Fluorescent Dye
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|
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain .
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- HY-W402148
-
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Fluorescent Dye
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|
10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide .
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- HY-D1688
-
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|
Fluorescent Dye
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|
Flubida-2 is a cell permeable dye which can be hydrolyzed to Fubi-2 by endoesterases in cells (after hydrolysis, Ex=492 nm, Em=517 nm). Flubida-2 can be used to detect pH at a specific site in a cell organelle by directing the probe to where avidin fusion proteins are located .
|
- HY-D2749
-
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Fluorescent Dye
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|
Sulfo-Bis-(N,N'-carboxylic acid)-Cy5 is a free unactivated carboxylic acid. Its absorbance and emission spectra are identical with Cy5 fluorophore.
|
- HY-145493
-
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Fluorescent Dye
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|
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .
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- HY-D2547
-
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Fluorescent Dye
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Cy5-PEG5000-biotin is a polyethylene glycol derivative containing Cy5 (HY-D0821) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5-PEG5000-biotin plays an important role in the specific capture and detection of biomolecules.
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- HY-151755
-
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Fluorescent Dye
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|
Sulfo-Cy3-Tetrazine is a click chemistry reagent containing an tetrazine group. Sulfo-Cy3-Tetrazine is water soluble cyanine fluorescence dye, which is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.
|
- HY-D1952
-
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Fluorescent Dye
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|
ATTO 594 Amine is an amine derivative of ATTO 594, the maximum excitation/emission wavelength: 603/626 nm.
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- HY-W440914C
-
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Fluorescent Dye
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DSPE-PEG600-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG600-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers (Ex/Em=488/525 nm) .
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- HY-D1581
-
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Fluorescent Dye
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BODIPY 505/515-8-C3-COOH is a green fluorescing derivative, as a fluorescent dye for imaging lipid droplets in nannochloropsis. BODIPY 505/515-8-C3-COOH can be used for the research of flow cytometric high-throughput screening and cell sorting .
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- HY-D1454
-
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Fluorescent Dye
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Nitro Blue Diformazan is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1747
-
- HY-D1632
-
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Fluorescent Dye
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|
4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH2. 4-MU-α-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .
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- HY-D1774
-
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|
Fluorescent Dye
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|
5-ROX-SE is the amine-reactive form of 5-carboxy-X-rhodamine single isomer.
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- HY-D0903
-
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DFO
|
Fluorescent Dye
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1,8-Diazafluoren-9-one (DFO) is a chemical that is used to find fingerprints on porous surfaces. 1,8-Diazafluoren-9-one reacts with amino acids present in the fingerprint to form highly fluorescent derivatives (Ex/Em = ~470/570).
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- HY-D2542
-
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|
Fluorescent Dye
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|
Cy5-PEG2000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG2000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2873
-
|
Sulfo Cy7(Et) tyramide
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Fluorescent Dye
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Sulfo Cy7 tyramide, a red fluorescent dye (Ex=740 nm, Em=770 nm), is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). Sulfo Cy7 tyramide can be used for multiplex Immunohistochemistry (mIHC) .
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- HY-D1072
-
|
3,3′-Dipentyloxacarbocyanine iodide
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Fluorescent Dye
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|
DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical .
|
- HY-D2132
-
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|
Fluorescent Dye
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Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .
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- HY-D2359
-
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Fluorescent Dye
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|
Glucosamine-FITC is FITC-labeled Glucosamine (HY-B1125). Glucosamine-FITC can be used to localize Glucosamine in living cells .
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- HY-D2691
-
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Fluorescent Dye
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|
Cy7.5 HA (MW 7000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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- HY-D2871
-
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Fluorescent Dye
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DAyne is a Dopamine (DA)-mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAyne is promising for research of Parkinson’s disease (PD), particularly neurotoxicity, protein modification, and related pathways (e.g., endoplasmic reticulum stress, cytoskeletal instability) caused by dopamine dysregulation .
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- HY-D1985
-
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Fluorescent Dye
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ATTO 725 Streptavidin is a streptavidin derivative of ATTO 725, it can label protein or antibody, the maximum excitation/emission wavelength: 728/751 nm.
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- HY-D2692
-
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Fluorescent Dye
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|
Cy7.5 HA (MW 10000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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- HY-175147
-
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Fluorescent Dye
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Progesterone 3-PEG11-biotin is an affinity probe. Progesterone 3-PEG11-biotin allows progesterone to be detected or immobilized using the biotin ligand.
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- HY-D2663
-
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Fluorescent Dye
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|
Cy5.5 HA (MW 500000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-D2712
-
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Fluorescent Dye
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Cy3 Dextran (MW 500000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-137042
-
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Alkyne-Cy5
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Fluorescent Dye
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|
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-DY3002
-
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Fluorescent Dye
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|
Glutaraldehyde Fixative (4%, For Electron Microscopy) is composed of glutaraldehyde, phosphate, deionized water, etc., with a pH range of 7.2-7.4. This fixative is effective in fixing fine structures of cell nuclei and cytoplasm and is commonly used for fixing electron microscopy specimens.
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- HY-D2050
-
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Fluorescent Dye
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|
ATTO 532 amine is an amine derivative of ATTO 532, the maximum excitation/emission wavelength: 532/552 nm.
|
- HY-130735
-
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JF646, SE; JF646, NHS
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Fluorescent Dye
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|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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- HY-D2221
-
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Fluorescent Dye
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Sulfo-Cy3 dUTP is a dUTP fluorescent dye containing sulfonated Cyanine3 group.
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- HY-D1339
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Fluorescent Dye
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Cyanine7 hydrazide dichloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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- HY-D1769
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Fluorescent Dye
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N-hydroxy Rhodamine B amide is a ClO - indicator, which is hydrolyzed to prduce fluorescence in the presence of ClO -. The fluorescence intensity of N-hydroxy Rhodamine B amide is proportional to the product, thus can be used to quantify ClO -.
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- HY-D1895
-
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Fluorescent Dye
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|
3,5-DiBr-PAESA is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .
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- HY-D2774
-
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|
Fluorescent Dye
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|
BP Fluor 488 Alkyne is a fluorophore. Its absorption and emission spectra are similar to fluorescein, but it is fluorescent in acidic media, and it is much more stable against photobleaching and oxidation.
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- HY-D2194
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Fluorescent Dye
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AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
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- HY-D1508
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Fluorescent Dye
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|
2-(Pyren-1-ylaminocarbonyl)ethyl methanethiosulfonate is a fluorescent .
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- HY-135415
-
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Fluorescent Dye
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|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
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- HY-D2154
-
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Fluorescent Dye
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|
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-D0114
-
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Fluorescent Dye
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|
3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye .
|
- HY-101882
-
BCECF
3 Publications Verification
2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein
|
Fluorescent Dye
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|
BCECF is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
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- HY-D1963
-
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Fluorescent Dye
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ATTO 565 Streptavidin is a streptavidin derivative of ATTO 565, it can label protein or antibody, the maximum excitation/emission wavelength: 564/590 nm.
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- HY-D1486
-
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Fluorescent Dye
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|
4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene is a fluorescent dye for DNA sequencing .
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- HY-130768
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Fluorescent Dye
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N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties. N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1513
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Fluorescent Dye
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|
O-Methyl-O-(N-butylfluorescein)phosphate is a fluorescent dye.
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- HY-D1716
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|
Fluorescent Dye
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|
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .
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- HY-D2415
-
|
|
Fluorescent Dye
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|
BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery .
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- HY-D2814
-
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|
Fluorescent Dye
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|
Chitosan-Cy7 (MW 100000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 100000) can be used for fluorescent labeling and imaging .
|
- HY-114351
-
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Fluorescent Dye
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|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
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- HY-D2856
-
|
|
Fluorescent Dye
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|
FITC-PEG1000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
- HY-D2100A
-
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|
Fluorescent Dye
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|
Cy5-DSPE chloride ammonium is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE chloride ammonium is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
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- HY-D1343
-
|
|
Fluorescent Dye
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|
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
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- HY-D1981
-
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|
Fluorescent Dye
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|
ATTO 633 Iodacetamid is an iodoacetamide derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.
|
- HY-D1350
-
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|
Fluorescent Dye
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|
5-ROX-alkyne is a rhodamine dye that labels DNA fragments. It enables visualization of the results of capillary electrophoresis genotyping experiments and gel shift experiments.
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- HY-D2708
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 10000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
- HY-107864
-
|
Tetraiodofluorescein
|
Fluorescent Dye
|
|
Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .
|
- HY-D2142
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-D1958
-
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|
Fluorescent Dye
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|
ATTO 565 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 564/590 nm.
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- HY-151753
-
|
|
Fluorescent Dye
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
|
- HY-D1706
-
|
|
Fluorescent Dye
|
|
AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA .
|
- HY-59021
-
|
|
Fluorescent Dye
|
|
2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole is a laser dyes with high photoluminescence (PL) quantum efficiency .
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- HY-D2794A
-
|
|
Fluorescent Dye
|
|
FITC-PEG1000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG1000-NH2 can be used for fluorescent labeling and imaging .
|
- HY-D2001A
-
|
|
Fluorescent Dye
|
|
TTO 488 NHS ester TEA is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. TTO 488 NHS ester TEA is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
- HY-110257
-
|
|
Fluorescent Dye
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|
BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λabs: 504 nm; λem:510 nm .
|
- HY-D0161
-
|
|
Fluorescent Dye
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|
ZnAF-2F DA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D0211
-
|
|
Fluorescent Dye
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|
Phenolphthalein is an acid-base indicator that is colorless in an acidic environment and pink in an alkaline environment. Phenolphthalein is genotoxic and potentially carcinogenic to mice. In addition, phenolphthalein is also a blood indicator .
|
- HY-D2387
-
|
|
Fluorescent Dye
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|
Sulfo CY3.5 hydrazide is sulfonated Cy3.5 with good water solubility. λex=591 nm, λem=604 nm.
|
- HY-111956A
-
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|
Fluorescent Dye
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
- HY-D1767
-
- HY-D1957
-
|
|
Fluorescent Dye
|
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
- HY-D2665
-
|
|
Fluorescent Dye
|
|
Cy5.5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
- HY-D2277
-
|
|
Fluorescent Dye
|
|
Fluorescein-CM2 is a fluorogenic molecule that can be used to rapidly screen esterase cut sites for protein-protein interaction-dependent (PPI-dependent) esterase activity in E. coli .
|
- HY-D1523
-
|
|
Fluorescent Dye
|
|
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm) .
|
- HY-D2840
-
|
|
Fluorescent Dye
|
|
FITC-mPEG350 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG350 can be used for fluorescent labeling and imaging .
|
- HY-D0283
-
- HY-D2858A
-
|
|
Fluorescent Dye
|
|
8-arm-PEG20000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
- HY-D0095
-
|
|
Fluorescent Dye
|
|
B261 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2019
-
|
|
Fluorescent Dye
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
- HY-D2597
-
|
|
Fluorescent Dye
|
|
Cy7.5-PEG2000-biotin is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5-PEG2000-biotin is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em=770/820 nm).
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- HY-D1867
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
- HY-D2228
-
|
|
Fluorescent Dye
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|
IR-7 is a mitochondria-targeted heptamethylindocyanine dye, and can used for cancer study.
|
- HY-135414A
-
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Fluorescent Dye
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
- HY-103466
-
|
|
Fluorescent Dye
|
|
FM4-64 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers.
|
- HY-W330621
-
|
CNP-α-D-Glucopyaoside
|
Fluorescent Dye
|
|
2-Chloro-4-nitrophenyl-α-D-glucopyranoside (CNP-α-D-Glucopyaoside) as a chromogenic substrate for the enzymatic activity assay of the enzyme that releases CNP from conjugated carbohydrates .
|
- HY-D1744
-
|
|
Fluorescent Dye
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
- HY-125746
-
|
|
Fluorescent Dye
|
|
BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
|
- HY-D2134
-
|
|
Fluorescent Dye
|
|
Cy5-PEG3-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-139579
-
|
OTL 38
|
Fluorescent Dye
|
|
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775 nm and emits at 794 to 796 nm .
|
- HY-D0922A
-
|
|
Fluorescent Dye
|
|
Cy3.5 acetate is a fluorescent dye that can be used to label antibodies .
|
- HY-D2800B
-
|
|
Fluorescent Dye
|
|
FITC-PEG3400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG3400-MAL can be used for fluorescent labeling and imaging .
|
- HY-D1310
-
|
|
Fluorescent Dye
|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
- HY-D2826E
-
|
|
Fluorescent Dye
|
|
FITC-Chitosan (MW 2000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 2000) can be used for fluorescent labeling and imaging .
|
- HY-D2796C
-
|
|
Fluorescent Dye
|
|
FITC-PEG10000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG10000-OH can be used for fluorescent labeling and imaging .
|
- HY-D1948
-
|
|
Fluorescent Dye
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
- HY-D0121A
-
|
|
Fluorescent Dye
|
|
INDO 1 pentapotassium is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
|
- HY-D2529
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D0789
-
|
|
Fluorescent Dye
|
|
ANTS is a fluorescent dye (Excitation wavelength: 380 nm; Emission wavelength: 520 nm). ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage .
|
- HY-D0082R
-
|
|
Fluorescent Dye
|
|
7-Diethylamino-4-methylcoumarin (Standard) is the analytical standard of 7-Diethylamino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Diethylamino-4-methylcoumarin is a laser dye .
|
- HY-101900
-
|
Nile blue sulfate
|
Fluorescent Dye
|
|
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
- HY-D2609
-
|
|
Fluorescent Dye
|
|
ICG PEG1000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG1000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
- HY-D2848C
-
|
|
Fluorescent Dye
|
|
Chitosan-Cy5.5 (MW 100000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 100000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
- HY-D2242
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
- HY-173418
-
|
cPGI-biotin; Carbacyclin-biotin
|
Fluorescent Dye
|
|
Carbaprostacyclin-biotin (cPGI-biotin; Carbacyclin-biotin) is a biotin-bound Carbacyclin (Carbaprostacyclin) (HY-112322). Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation .
|
- HY-D2848B
-
|
|
Fluorescent Dye
|
|
Chitosan-Cy5.5 (MW 1000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 1000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
- HY-DY3001
-
|
|
Fluorescent Dye
|
|
Glutaraldehyde Fixative (2.5%, For Electron Microscopy) is composed of glutaraldehyde, phosphate, deionized water, etc., with a pH range of 7.2-7.4. This fixative is effective in fixing fine structures of cell nuclei and cytoplasm and is commonly used for fixing electron microscopy specimens.
|
- HY-D2772
-
|
|
Fluorescent Dye
|
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
- HY-D2098
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG2-NH2 is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
|
- HY-D1502
-
|
|
Fluorescent Dye
|
|
FURA-PE3/AM is a leak-resistant fluorescent calcium indicator dye .
|
- HY-DY1067
-
|
|
Fluorescent Dye
|
Cy5 maleimide (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
- HY-101880
-
ADHP
2 Publications Verification
10-Acetyl-3,7-dihydroxyphenoxazine
|
Fluorescent Dye
|
|
ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
|
- HY-W998687
-
|
|
Fluorescent Dye
|
|
Cy5 dimethyl is a free non-activated dye. This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration.
|
- HY-D2796A
-
|
|
Fluorescent Dye
|
|
FITC-PEG1000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG1000-OH can be used for fluorescent labeling and imaging .
|
- HY-D0722
-
|
5-(6)-Carboxyfluorescein diacetate; CFDA
|
Fluorescent Dye
|
|
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
- HY-D1080
-
EDANS
3 Publications Verification
1,5-EDANS
|
Fluorescent Dye
|
|
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) .
|
- HY-135367
-
|
Pyridyl CTZ
|
Fluorescent Dye
|
|
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .
|
- HY-D2071
-
|
|
Fluorescent Dye
|
|
ATTO 680 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 681/698 nm.
|
- HY-DY1070
-
|
|
Fluorescent Dye
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (solution) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-D2437
-
|
|
Fluorescent Dye
|
|
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .
|
- HY-D1862
-
|
|
Fluorescent Dye
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D2170
-
|
|
Fluorescent Dye
|
|
AF488 streptavidin is a fluorescently labeled streptavidin. AF488 streptavidin is a streptavidin conjugated to Alexa Fluor 488, with 4 fluorophores per protein molecule, enabling stoichiometric fluorescent labeling of cell surface targets. AF488 streptavidin can form a complex with biotinylated E07 aptamer to stain cells expressing EGFR, and the staining is reversible after treatment with mA9 detoxifying oligonucleotides (Ex/Em = 470/520 nm) .
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- HY-D2064
-
|
|
Fluorescent Dye
|
|
ATTO 680 streptavidin is a streptavidin derivative of ATTO 680, it can label protein or antibody, the maximum excitation/emission wavelength: 681/698 nm.
|
- HY-D1921
-
|
|
Fluorescent Dye
|
|
ATTO 390 iodoacetamide is the iodoacetamide derivative of ATTO 390, the maximum excitation/emission wavelength: 390/476 nm.
|
- HY-D2677
-
|
|
Fluorescent Dye
|
|
Cy7 HA (MW 100000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
- HY-D1497
-
|
|
Fluorescent Dye
|
|
Fluorescent Red Mega 480 is a dye that is specifically designed for multicolor techniques. Fluorescent Red Mega 480 is characterized by an extremely large stoke′s shift between excitation and emission maxima .
|
- HY-D2181
-
|
|
Fluorescent Dye
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
- HY-137928
-
|
|
Fluorescent Dye
|
|
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .
|
- HY-W142395
-
|
|
Fluorescent Dye
|
|
6-TAMRA free acid is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry.
|
- HY-D2188
-
|
|
Fluorescent Dye
|
|
IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .
|
- HY-D2825
-
|
|
Fluorescent Dye
|
|
Chitosan-Cy7.5 (MW 100000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 100000) can be used for fluorescent labeling and imaging .
|
- HY-D1358
-
|
|
Fluorescent Dye
|
|
Alkyne MegaStokes dye 608 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2056
-
|
|
Fluorescent Dye
|
|
ATTO 700 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 700/716 nm.
|
- HY-DY1011
-
|
|
Fluorescent Dye
|
PKH 26 (solution) is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm) , which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies .
Solvent and concentration: DMSO: 5 mM
|
- HY-101893
-
|
|
Fluorescent Dye
|
|
Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
|
- HY-D2675
-
|
|
Fluorescent Dye
|
|
Cy7 HA (MW 10000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
- HY-153524
-
|
|
Fluorescent Dye
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
- HY-W127705
-
|
|
Fluorescent Dye
|
|
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
|
- HY-D2229
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3.5 amine is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
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- HY-W591393
-
|
|
Fluorescent Dye
|
|
Biotin Azide Plus is an oxazolidine reagent that integrates azide-biotin click chemistry and a photocleavable linker arm. Biotin Azide Plus not only reacts with biotin thioether to form stable sulfinimide products, but also enables bioconjugation of proteins and DNA through biotin redox-activated chemical labeling technology. Taking advantage of the streptavidin capture and photo-release properties, Biotin Azide Plus effectively facilitates the isolation of lipid-derived electrophile-protein adducts, thus finding wide application in scientific research related to fields such as SKBR3 cancer .
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- HY-W073524
-
|
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Fluorescent Dye
|
|
DFAME is a red fluorophore (Ex = 508 nm, Em = 641 nm). DFAME binds to Beetroot and Corn (dimeric fluorescent RNA aptamers) to form Beetroot-DFAME (Kd = 460 nM) and Corn-DFAME (Kd = 3600 nM). Beetroot-DFAME and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research .
|
- HY-D2166
-
|
|
Fluorescent Dye
|
|
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
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- HY-D1760
-
|
|
Fluorescent Dye
|
|
SBFI is a cell-impermeant, fluorescent Na + indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm . SBFI selective for Na + over K + with Kd values of 20 and 120 mM for these ions, respectively. .
|
- HY-D3064
-
|
|
Fluorescent Dye
|
|
510 Calibration probe is a chemiluminescent group that can be used as a probe for in vivo imaging studies, with an emission maximum around 520 nm .
|
- HY-D2355
-
|
|
Fluorescent Dye
|
|
Tris-NTA Biotin is a biotin-labeled version of tris-NTA. Tris-NTA Biotin, as a bridge connecting His-tagged proteins with streptavidin, can reversibly label proteins and cell surfaces. Tris-NTA Biotin can be used in experiments such as protein immobilization, kinetic determination, live cell labeling, and Western blot detection .
|
- HY-D1043
-
|
|
Fluorescent Dye
|
|
1,4-Dichloro 6-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
|
- HY-156305
-
|
|
Fluorescent Dye
|
|
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.
|
- HY-D2534
-
|
|
Fluorescent Dye
|
|
Cy5-PEG3400-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-129109
-
|
|
Fluorescent Dye
|
|
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H2O2, ClO -, O2 -?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .
|
- HY-D0214A
-
|
|
Fluorescent Dye
|
|
Acid Red 94 lactone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1984
-
|
|
Fluorescent Dye
|
|
ATTO 633 Alkin is an alkyne derivative of ATTO 594 with excitation/emission maxima at 630/651 nm.
|
- HY-D0720
-
|
NSC-151912; L-6868
|
Fluorescent Dye
|
|
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
|
- HY-124324
-
|
p-Nitopheyl β-D-cellotioside
|
Fluorescent Dye
|
|
4-Nitrophenyl β-D-cellotrioside (p-Nitopheyl β-D-cellotioside) is a chromogenic substrate for endoglucanases and cellulose biohydrolases. As a fluorescent dye, nitrophenyl β-D-Cellotrioside can be hydrolyzed by enzymes to release 4-nitrophenol, producing a yellow color. The activity of the enzyme can be quantitatively analyzed by monitoring the change in absorbance at 405 nm .
|
- HY-D1754
-
|
LYCH ammonium
|
Fluorescent Dye
|
|
Lucifer yellow CH (LYC) ammonium is a thiol-reactive fluorescent polar tracer.
|
- HY-D2857
-
|
|
Fluorescent Dye
|
|
NBD-Stearic acid is a stearic acid labeled with a nitrobenzoxadiazole (NBD) fluorophore. NBD-Stearic acid can be used as a probe for fatty acid uptake or the the ligand binding sites of fatty acid and sterol carrier proteins (FABP)
|
- HY-D1668
-
|
|
Fluorescent Dye
|
|
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
|
- HY-D2320
-
|
|
Fluorescent Dye
|
|
ER Flipper-TR 28 is a flipper probe with a small molecule fluorophore that can image membrane tension in the endoplasmic reticulum (ER). ER Flipper-TR 28 bears a pentafluorophenyl group and also reacts with protein thiolate on the ER surface facing the cytoplasm .
|
- HY-D1436
-
|
|
Fluorescent Dye
|
|
PBFI is the cell-impermeant fluorescent indicator that is widely used for the determination of concentrations of K + (Ex/Em = 340,380/500 nm) .
|
- HY-D1048
-
|
Cy7 DiC18
|
Fluorescent Dye
|
|
DiR is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
- HY-32264
-
|
X-NeuNAc
|
Fluorescent Dye
|
|
X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase.
|
- HY-118540
-
|
Diazoresorcinol
|
Fluorescent Dye
|
|
Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
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- HY-D2044
-
|
|
Fluorescent Dye
|
|
ATTO 532 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 532/552 nm.
|
- HY-DY1063
-
|
|
Fluorescent Dye
|
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM
|
- HY-D2826C
-
|
|
Fluorescent Dye
|
|
FITC-Chitosan (MW 10000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 10000) can be used for fluorescent labeling and imaging .
|
- HY-D1713
-
|
|
Fluorescent Dye
|
|
CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive .
|
- HY-D1993
-
|
|
Fluorescent Dye
|
|
ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .
|
- HY-D1749
-
|
|
Fluorescent Dye
|
|
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.
|
- HY-D1357
-
|
|
Fluorescent Dye
|
|
Alkyne MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2095
-
|
|
Fluorescent Dye
|
|
Medical fluorophore 33 is a novel quinoline-isoquinoline salt. Medical fluorophore 33 exhibits a strong fluorescent signal, good microsomal stability and high biocompatibility in vivo. Medical fluorophore 33 has antitumor activity in colorectal cancer mice .
|
- HY-110251
-
|
|
Fluorescent Dye
|
|
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
|
- HY-D1051
-
|
|
Fluorescent Dye
|
|
Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid. Cy3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 548/563 nm).
|
- HY-D2481
-
|
APG-2 (TMA)
|
Fluorescent Dye
|
|
Asante potassium green-2 (APG-2) TMA is a cell-impermeable K + (potassium ion) fluorescent indicator that produces a fluorescent response to changes in extracellular potassium ion concentration. Its excitation/emission maxima are 525/545 nm , respectively.
|
- HY-D1116
-
|
|
Fluorescent Dye
|
|
MitoMark Red I is a fluorescent mitochondrial marker. MitoMark Red I is a red fluorescent dye which accumulates in mitochondria in viable cells and has an excitation wavelength of 578 nm and emission of 599 nm .
|
- HY-D1488
-
|
|
Fluorescent Dye
|
|
Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate (Compound 3) is a Mg 2+ selective fluorescent indicator .
|
- HY-D1881
-
- HY-W011422
-
|
NSC 528
|
Fluorescent Dye
|
|
2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone (NSC 528) is a colorimetric dye used for the detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone reacts with phenolic compounds at a pH of about 9.4 to produce an indigo dye. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has been used as a Gibbs reagent for the colorimetric detection of phenolic compounds. 2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone has also been used in a colorimetric reaction for the quantitative colorimetric detection of aflatoxins, turning the colorless aflatoxins green with an absorption band at 673 nm.
|
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dye
|
|
Janelia Fluor 525, SE (JF525, SE) (the SE form of compound 12) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor 525, SE contains an NHS ester, which can be used to label primary amines and is suitable for live cell imaging.
|
- HY-D2012
-
|
|
Fluorescent Dye
|
|
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
|
- HY-D2645
-
|
|
Fluorescent Dye
|
|
Cy5 HA (MW 100000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
- HY-D2441
-
|
|
Fluorescent Dye
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
- HY-D3393
-
|
|
Fluorescent Dye
|
|
JQ1-FITC TFA is a BRD4-binding fluorescent tracer. JQ1-FITC TFA binds to BRD4 BD1, BD2, recombinant bromodomains, and endogenous BRD4 in cell lysates. JQ1-FITC TFA can be used for the research of breast cancer and cancer (Ex/Em = 495/525 nm) .
|
- HY-D1941
-
|
|
Fluorescent Dye
|
|
ATTO 590 Streptavidin is a streptavidin derivative of ATTO 590, it can label protein or antibody, the maximum excitation/emission wavelength: 594/622 nm.
|
- HY-D2559
-
|
|
Fluorescent Dye
|
|
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-DY1066
-
|
|
Fluorescent Dye
|
Cy3 (Sulfo-Cyanine3) (solution) is an orange-fluorescent label for protein and nucleic acid (λex=554, λem=568).
Solvent and concentration: DMSO: 10 mM
|
- HY-D2141
-
|
|
Fluorescent Dye
|
|
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W414549
-
|
|
Fluorescent Dye
|
|
FAM alkyne, 6-isomer is a click chemistry regent that can be used in 1,3-dipolar cycloaddition with azido-labeled compound .
|
- HY-D1401
-
|
|
Fluorescent Dye
|
|
OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences .
|
- HY-D1929
-
|
|
Fluorescent Dye
|
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
- HY-P1169
-
|
|
Fluorescent Dye
|
|
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
|
- HY-DY1050
-
|
|
Fluorescent Dye
|
Ethidium bromide (solution) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
Solvent and Concentration: Sterile water: 10 mg/Ml
|
- HY-D1701
-
|
|
Fluorescent Dye
|
|
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.
MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
|
- HY-131024
-
|
JF549, Tetrazine
|
Fluorescent Dye
|
|
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D2540
-
|
|
Fluorescent Dye
|
|
Cy3-PEG10000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2802A
-
|
|
Fluorescent Dye
|
|
FITC-PEG1000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG1000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-101879
-
|
|
Fluorescent Dye
|
|
Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
|
- HY-DY1052
-
|
|
Fluorescent Dye
|
Monochlorobimane (Chlorobimane) (solution) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
Solvent and concentration: DMSO: 10 mM
|
- HY-D1587
-
|
|
Fluorescent Dye
|
|
8-Phenyl-2,6-diethyl-BODIPY 505/515 is a derivative of BODIPY 505/515 (Ex=525 nm，Em=544 nm) .
|
- HY-D2307
-
|
Fluoroacetyl-coenzyme A
|
Fluorescent Dye
|
|
Fluoroacetyl-CoA (Fluoroacetyl-coenzyme A) is a coenzyme A derivative .
|
- HY-D1546
-
|
|
Fluorescent Dye
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
- HY-D2693
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA (MW 50000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
- HY-DY1084
-
|
|
Fluorescent Dye
|
DiD perchlorate (solution)is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
Solvent and concentration: DMSO: 5 mM
|
- HY-D2632
-
|
|
Fluorescent Dye
|
|
Cy3 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
- HY-D2744
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 TCO reacts with tetrazines to produce a stable, covalent linkage, also referred to as the inverse-electron demand Diels-Alder cycloaddition reaction. This reaction is extremely fast (k > 800 M-1 s-1), selective, biocompatible, and does not require Cu-catalyst or elevated temperatures. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
|
- HY-D2845B
-
|
|
Fluorescent Dye
|
|
4-Arm-PEG10000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG10000-FITC can be used for fluorescent labeling and imaging .
|
- HY-D0022
-
|
5-AF
|
Fluorescent Dye
|
|
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .
|
- HY-101902
-
|
Quin-2 acetoxymethyl ester
|
Fluorescent Dye
|
|
Quin-2AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Quin-2AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
- HY-W923198
-
|
Methacryloyloxy fluorescein
|
Fluorescent Dye
|
|
Fluorescein O-methacrylate (Methacryloyloxy fluorescein) is a pH-responsive fluorescent monomeric dye. Fluorescein O-methacrylate exhibits pH-responsive fluorescence properties: its fluorescence is activated under alkaline conditions and quenched under neutral or acidic conditions; reversible switching of fluorescence is achievable by adjusting the pH of the solution. Fluorescein O-methacrylate can be used as a monomer for the synthesis of amphiphilic fluorescein polymers. These polymers can self-assemble into stable polymer nanoparticles with enhanced aqueous-phase fluorescence, and also enable the conjugation of nanoparticles with amine-containing biomolecules to support sensitive optical detection of biomarkers (Ex/Em = 490/520 nm) .
|
- HY-W248115
-
|
|
Fluorescent Dye
|
|
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .
|
- HY-101896
-
|
|
Fluorescent Dye
|
|
Fluo-4 AM is a cell-permeable Ca 2+ (calcium ion) indicator (Ex/Em = 485/526 nm) .
|
- HY-D0924B
-
|
Sulfo-Cyanine5.5 TEA
|
Fluorescent Dye
|
|
Cy5.5 TEA is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1951
-
|
|
Fluorescent Dye
|
|
ATTO 594 Biotin is a biotin derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
|
- HY-D2598
-
|
|
Fluorescent Dye
|
|
Cy7.5-PEG5000-biotin is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5-PEG5000-biotin is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em=770/820 nm).
|
- HY-D1768
-
|
|
Fluorescent Dye
|
|
Fluo-4FF AM is a cell-permeant fluorescent calcium indicator. Fluo-4FF is an analog of Fluo-4 with a lower affinity for calcium, which is suitable for investigation of relatively high level of intracellular calcium.
|
- HY-D2688
-
|
|
Fluorescent Dye
|
|
Cy7 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
|
- HY-D2671
-
|
|
Fluorescent Dye
|
|
Cy5.5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
|
- HY-D2705
-
|
|
Fluorescent Dye
|
|
Cy3 Dextran (MW 2000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
|
- HY-D1899
-
|
|
Fluorescent Dye
|
|
VIC phosphoramidite, 6-isomer is a VIC derivative that can be used for conjugating VIC to other molecules. VIC can be used for labeling oligonucleotides at the 5’-end .
|
- HY-D2499
-
|
|
Fluorescent Dye
|
|
Sulfo Cy7 DBCO potassium is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. Sulfo Cy7 DBCO potassium is a click chemistry reagent. Sulfo Cy7 DBCO potassium contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-131022
-
|
JF549 TFA
|
Fluorescent Dye
|
|
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D2796B
-
|
|
Fluorescent Dye
|
|
FITC-PEG5000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG5000-OH can be used for fluorescent labeling and imaging .
|
- HY-D2519
-
|
|
Fluorescent Dye
|
|
Cy3-PEG2000-biotin is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy3-PEG2000-biotin plays an important role in the specific capture and detection of biomolecules .
|
- HY-D0819A
-
|
Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
|
Fluorescent Dye
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
- HY-D1611
-
|
|
Fluorescent Dye
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
|
- HY-135056
-
|
|
Fluorescent Dye
|
|
Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.
|
- HY-D2604
-
|
|
Fluorescent Dye
|
|
ICG PEG1000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG1000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
- HY-DY1061
-
|
|
Fluorescent Dye
|
BODIPY 558/568 C12 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
Solvent and concentration: DMSO: 2 mM
|
- HY-D0006A
-
|
|
Fluorescent Dye
|
|
Bathophenanthroline disulfonic acid sodium is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-15935C
-
|
|
Fluorescent Dye
|
|
X-Gluc sodium is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue) .
|
- HY-D0824
-
|
Sulfo-Cyanine7 Succinimidyl Ester
|
Fluorescent Dye
|
|
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D2801B
-
|
|
Fluorescent Dye
|
|
FITC-PEG3400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG3400-NHS can be used for fluorescent labeling and imaging .
|
- HY-D1529
-
|
|
Fluorescent Dye
|
|
4-Methylumbelliferyl phosphate (2-amino-2-methyl-1,3-propanediol) is a fluorescent substrate, can be used as substrate buffer of enzyme assay .
|
- HY-D2196
-
|
|
Fluorescent Dye
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window.
|
- HY-104057
-
|
|
Fluorescent Dye
|
|
Rhod-FF AM is a fluorescent calcium indicator. Rhod-FF AM is cell permeable and is hydrolyzed by intracellular esterases to generate Rhod-FF .
|
- HY-D1235
-
|
|
Fluorescent Dye
|
|
Fluorescent brightener 210 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2612
-
|
|
Fluorescent Dye
|
|
ICG PEG5000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG5000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
- HY-D3389
-
|
|
Fluorescent Dye
|
|
sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .
|
- HY-D0051
-
|
|
Fluorescent Dye
|
|
5(6)-Carboxy-eosin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1418
-
|
|
Fluorescent Dye
|
|
CP-BP-SFAC is a luminogenic molecule. CP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films .
|
- HY-D2854C
-
|
|
Fluorescent Dye
|
|
FITC-PEG3400-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
- HY-D2842
-
|
|
Fluorescent Dye
|
|
FITC-PEG400-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG400-biotin can be used for fluorescent labeling and imaging .
|
- HY-D0112
-
|
|
Fluorescent Dye
|
|
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm) .
|
- HY-101892
-
|
|
Fluorescent Dye
|
|
DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential.
|
- HY-D0893
-
|
|
Fluorescent Dye
|
|
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
|
- HY-D2055
-
|
|
Fluorescent Dye
|
|
ATTO 532 cadaverin is a cadaverine derivative of ATTO 532, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 532/552 nm.
|
- HY-D0010
-
|
Dibromopyrogallolsulfonphthaleine
|
Fluorescent Dye
|
|
Bromopyrogallol red (Dibromopyrogallolsulfonphthaleine) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1748
-
|
|
Fluorescent Dye
|
|
Rhodamine B hexyl ester perchlorate is a cell-permeant, orange-fluorescent dye for mitochondria.
|
- HY-D2796
-
|
|
Fluorescent Dye
|
|
FITC-PEG400-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG400-OH can be used for fluorescent labeling and imaging .
|
- HY-D1261
-
|
Thiol-green 1
|
Fluorescent Dye
|
|
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells . Ex: 488 nM; Em: 540 nM.
|
- HY-D2678
-
|
|
Fluorescent Dye
|
|
Cy7 HA (MW 500000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
- HY-D1990
-
|
|
Fluorescent Dye
|
|
ATTO 620 Azide is an azide derivative of ATTO 520 with excitation/emission maxima at 620/642 nm.
|
- HY-D2171A
-
|
|
Fluorescent Dye
|
|
AF488 DBCO ditriethylamineis a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO ditriethylaminemediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
- HY-D2152
-
|
|
Fluorescent Dye
|
|
Cy5-PEG3-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
- HY-D2240
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3.5-DBCO is a fluorescent dye. Sulfo-Cy3.5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D1999
-
|
|
Fluorescent Dye
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
- HY-D2068
-
|
|
Fluorescent Dye
|
|
ATTO 680 iodacetamid is an iodoacetamide derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
|
- HY-118159
-
|
DPPP
|
Fluorescent Dye
|
|
Diphenyl-1-pyrenylphosphine (DPPP) is a functional organic molecule with both fluorescent properties and metal coordination ability, which is commonly used in materials and coordination chemistry research. Upon exposure to ultraviolet light, Diphenyl-1-pyrenylphosphine undergoes photoinduced phosphorus atom oxidation to form O-DPPP, triggering a transition from aggregation-induced emission (AIE) to aggregation-caused quenching (ACQ). Diphenyl-1-pyrenylphosphine reacts stoichiometrically with lipid hydroperoxides to produce fluorescent diphenyl-1-pyrenylphosphine oxide. Diphenyl-1-pyrenylphosphine can insert into cell membranes to monitor lipid peroxidation processes in living cells .
|
- HY-D0026
-
|
7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
|
Fluorescent Dye
|
|
AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .
|
- HY-D2175
-
|
|
Fluorescent Dye
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 552/566 nm) .
|
- HY-D2192
-
- HY-D2633
-
|
|
Fluorescent Dye
|
|
Cy3 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
- HY-D1868
-
|
|
Fluorescent Dye
|
|
Cy3 azide plus is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with an azide functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The azide group of Cy3 azide plus can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-156309
-
|
|
Fluorescent Dye
|
|
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-172268
-
|
|
Fluorescent Dye
|
|
R6G phosphoramidite for oligonucleotide synthesis, pure 6-isomer. R6G (rhodamine 6G) is a xanthene dye of the rhodamine family with high fluorescence quantum yield and high molar extinction coefficient. Relative to those of fluorescein, the absorption (518 nm) and emission (542 nm) maxima of 6-R6G are shifted into the long-wave region.
|
- HY-D2024
-
|
|
Fluorescent Dye
|
|
ATTO 550 streptavidin is a streptavidin derivative of ATTO 550, it can label protein or antibody, the maximum excitation/emission wavelength: 554/576 nm.
|
- HY-W008292
-
|
|
Fluorescent Dye
|
|
Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion .
|
- HY-D0083
-
|
DiIC18(3)
|
Fluorescent Dye
|
|
DiI is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
- HY-D2626
-
|
|
Fluorescent Dye
|
|
Cy3 HA (MW 100000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
- HY-DY2002
-
|
|
Fluorescent Dye
|
X-GAL (BCIG) (solution) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
Solvent and Concentration: DMF: 20 mg/mL
|
- HY-D1932
-
|
|
Fluorescent Dye
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
- HY-D0100
-
|
|
Fluorescent Dye
|
|
Fluorescein-diacetate-5-isothiocyanat is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
- HY-D2101
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
|
- HY-D2610
-
|
|
Fluorescent Dye
|
|
ICG PEG2000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG2000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
- HY-W998680
-
|
5-FITC-Maleimide
|
Fluorescent Dye
|
|
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
|
- HY-D148410F
-
|
Cy5-STK-001 negative control
|
Fluorescent Dye
|
|
Cy5-Zorevunensen negative control (Cy5-STK-001 negative control) is an antisense oligonucleotide labeled with the fluorescent molecule Cy5, which can be used as a negative control for Zorevunersen (HY-148410) .
|
- HY-132270
-
|
|
Fluorescent Dye
|
|
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
|
- HY-D2672
-
|
|
Fluorescent Dye
|
|
Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
- HY-D2741
-
|
|
Fluorescent Dye
|
|
MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D1734
-
|
|
Fluorescent Dye
|
|
FITC-GW3965 is a fluorescence-labelled liver X receptor β (LXRβ) agonist GW3965 (HY-10627). FITC-GW3965 is a tracer, that can be designed by replacing the trifluoromethyl of GW3965 with an amide to link the FITC. FITC-GW3965 can be used to study the function of LXRβ .
|
- HY-D1385
-
|
|
Fluorescent Dye
|
|
JF526–Pepstatin A TFA is a fluorescent dye that can be used for lysosomal staining in live cells. The excitation maximum is 530 nm and the emission maximum is 549 nm .
|
- HY-D2872
-
|
|
Fluorescent Dye
|
|
5-AF594 tyramide is a red fluorescent dye (Ex=590 nm, Em=618 nm). 5-AF594 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-AF594 tyramide can be used for multiplex immunohistochemistry (mIHC) .
|
- HY-D2073
-
|
|
Fluorescent Dye
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
- HY-DY1038
-
|
|
Fluorescent Dye
|
Acridine Orange hydrochloride (solution) is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
Solvent and Concentration: Sterile water: 10 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-D1251
-
|
|
Fluorescent Dye
|
|
TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells .
|
- HY-D2836E
-
|
FITC-Hyaluronate (MW 10000)
|
Fluorescent Dye
|
|
FITC-HA (MW 10000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
- HY-D2594
-
|
|
Fluorescent Dye
|
|
Cy7.5-PEG3400-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
|
- HY-D2533
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1447
-
|
|
Fluorescent Dye
|
|
Fluo-3FF pentapotassium is a cell-impermeant fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
|
- HY-W440914A
-
|
|
Fluorescent Dye
|
|
DSPE-PEG400-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG400-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .
|
- HY-D1979
-
|
|
Fluorescent Dye
|
|
ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
- HY-D2628
-
|
|
Fluorescent Dye
|
|
Cy3 HA (MW 500000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
- HY-D2851B
-
|
|
Fluorescent Dye
|
|
FITC-PEG5000-CHOL is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG5000-CHOL is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em=488/525 nm) .
|
- HY-D1850
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2079
-
|
|
Fluorescent Dye
|
|
ATTO 665 azide is an azide derivative of ATTO 665 with excitation/emission maxima at 663/680 nm.
|
- HY-D2161A
-
|
|
Fluorescent Dye
|
|
AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne) .
|
- HY-D1268
-
|
|
Fluorescent Dye
|
|
Seph-PAO is the modified PAO attached a sepharose fluorophore and is used to detect the thioredoxin reductase (TrxR) .
|
- HY-D2627
-
|
|
Fluorescent Dye
|
|
Cy3 HA (MW 200000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
- HY-D0969
-
|
DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate
|
Fluorescent Dye
|
|
DiO is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
- HY-D2647
-
|
|
Fluorescent Dye
|
|
Cy5 HA (MW 500000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
- HY-D2324
-
|
|
Fluorescent Dye
|
|
EE-Flipper 33 is a Flipper probe designed to evaluate the mechanism of early endocytosis. EE-Flipper has a pKa value of 10.6 and is capable of tracking approximately 70% of early endosomes (EE) in live cells. Furthermore, EE-Flipper 33 can also label the Golgi apparatus in live cells with an internal pH ranging from 6.0 to 6.7 .
|
- HY-D1515
-
|
Neurodye GH1-84
|
Fluorescent Dye
|
|
FM1-84 (Neurodye GH1-84) is a fluorescent dye. FM1-84 has lipophilic and facilitates association with membranes, resulting in an increase in fluorescence intensity (λex=510 nm, λem=625 nm). FM1-84 can be used for synaptic vesicle recycling in neurons research .
|
- HY-P1005
-
|
|
Fluorescent Dye
|
|
Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
|
- HY-101974
-
|
|
Fluorescent Dye
|
|
Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.
|
- HY-N0729F
-
|
|
Fluorescent Dye
|
|
BODIPY-Linoleic acid is a conjugate of the BODIPY fluorophore and Linoleic acid (HY-N0729) (C18:2) and is a lipid metabolism probe.
|
- HY-138658
-
|
JF526, SE; JF526, NHS
|
Fluorescent Dye
|
|
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0078
-
|
|
Fluorescent Dye
|
|
DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein .
|
- HY-151662
-
|
N3-TFBA
|
Fluorescent Dye
|
|
4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1853A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5 carboxylic acid TEA is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
|
- HY-D1753
-
|
LYC
|
Fluorescent Dye
|
|
Lucifer yellow cadaverine (LYC) can be used as a cell tracer. Lucifer yellow cadaverine can be used to label endocytic vacuoles in cells .
|
- HY-D2018
-
|
|
Fluorescent Dye
|
|
ATTO 550 carboxy is a carboxyl derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
|
- HY-DY1037
-
|
|
Fluorescent Dye
|
Dihydrorhodamine 123 (DHR 123) (solution) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
Solvent and concentration: DMSO: 10 mM
|
- HY-151615
-
|
|
Fluorescent Dye
|
|
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB) .
|
- HY-D1109
-
|
|
Fluorescent Dye
|
|
5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins .
|
- HY-121608
-
|
Lumiflavine
|
Fluorescent Dye
|
|
Lumiflavin (Lumiflavine), a riboflavine analog, causes significant inhibition of riboflavine uptake. Lumiflavin can effectively reduce the riboflavin enrichment in cancer stem-like cells (CSCs) and sensitize the effect of cisplatin Diamminedichloroplatinum (DDP) on CSCs. Lumiflavin is promising for research of ovarian cancer .
|
- HY-D125859F
-
|
HRP-Biotin
|
Fluorescent Dye
|
|
Peroxidase, Horseradish, Biotin labeled (HRP-Biotin) can be used to encapsulate DNA nanoflowers for creating stabilized streamlined ELISA platforms resistant to harsh environment .
|
- HY-D2770
-
|
|
Fluorescent Dye
|
|
Cyanine3.5 dimethyl is a non-sulfonated cyanine dye with good solubility in organic solvents and bright fluorescence in the yellow-orange spectrum range. The dye can be used as a non-reactive fluorophore for control experiments, calibration, and other technical applications.
|
- HY-D1390A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
- HY-D2698
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
|
- HY-D0952
-
|
|
Fluorescent Dye
|
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Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays .
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- HY-D2701
-
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Fluorescent Dye
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Cy7.5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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- HY-15923
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Fluorescent Dye
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MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium .
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- HY-D2523
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Fluorescent Dye
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Cy3-PEG2000-FA is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG2000-FA can be readily traced by its intense red fluorescent signal. Cy3-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection.
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- HY-D1249
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Fluorescent Dye
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Calcein (mixture of isomers), Calcein (HY-D0040) Derivative, is a fluorescent dye (Ex/Em = 495/515 nm). Calcein (mixture of isomers) can be used for the researches for live cell staining, calcium ion detection, bone fluorescence labeling and membrane permeability leakage detection.
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- HY-D2683
-
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Fluorescent Dye
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Cy7 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2799
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Fluorescent Dye
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Chitosan-Cy7 (MW 7000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 7000) can be used for fluorescent labeling and imaging .
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- HY-D1593
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Fluorescent Dye
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BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.
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- HY-D2147
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Fluorescent Dye
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Cy5-PEG7-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D0141
-
- HY-D0069
-
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Fluorescent Dye
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CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
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- HY-149117
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Fluorescent Dye
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AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
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- HY-W039519
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Fluorescent Dye
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7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
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- HY-D2851
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Fluorescent Dye
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FITC-PEG2000-CHOL is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG2000-CHOL is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em=488/525 nm) .
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- HY-D1852
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Fluorescent Dye
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Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D1189
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Lucifer Yellow 3-amino-D-alanine
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Fluorescent Dye
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YADA (Lucifer Yellow 3-amino-D-alanine) is a conjugate of the fluorescent dyes Lucifer yellow and D-alanine, which is a green-yellow fluorescent dye. YADA is suitable for labeling peptidoglycans in living bacteria that can be incorporated into the cell wall where they are being synthesized. YADA has a large Stokes shift and a wide emission spectrum, allowing excitation through a purple light source and detection using a green filter. YADA showed good water solubility, light stability and thermal stability.
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- HY-D1848
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Fluorescent Dye
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Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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- HY-D2037
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Fluorescent Dye
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ATTO 550 hydrazid is a hydrazide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
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- HY-D1068
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DBCO-Sulfo-Cy5
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Fluorescent Dye
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Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-155325
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Fluorescent Dye
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Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-D1318
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Fluorescent Dye
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Cyanine7.5 azide chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with an azide functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Cyanine7.5 azide chloride can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Cyanine7.5 azide chloride can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-117695
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6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
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Fluorescent Dye
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AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
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- HY-D2563
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Fluorescent Dye
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Cy5.5-PEG10000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1298
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Fluorescent Dye
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Dye 40 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-136247
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Tyramide-Cy5
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Fluorescent Dye
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Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .
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- HY-D1567
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Fluorescent Dye
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Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
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- HY-D1366A
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Fluorescent Dye
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Sulfo-Cyanine5.5 carboxylic acid potassium is a fluorescent dye with excitation/emission wavelengths at 673/707 nm. The introduction of the sulfite group enhances the hydrophilic properties of the compound. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC and HATU, to form stable amide bonds.
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- HY-D1381
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Fluorescent Dye
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CH1055-PEG is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0211R
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Fluorescent Dye
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Phenolphthalein (Standard) is the analytical standard of Phenolphthalein. This product is intended for research and analytical applications. Phenolphthalein is a widely applied but toxic indicator dye.
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- HY-D2432
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- HY-D2028
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Fluorescent Dye
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ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
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- HY-D2848
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Fluorescent Dye
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Chitosan-Cy5.5 (MW 2000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 2000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
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- HY-158726
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Fluorescent Dye
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Complex 3 is a fluorescent dithiocarbazate-copper complex with anticancer activity, which localizes to mitochondria. Complex 3 displays excitation/emission maxima of 455-495/535 nm, respectively. Complex 3 inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Complex 3 induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells. Complex 3 also induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in AsPC-1 cells. Complex 3 reduces tumor volume in an AsPC-1 mouse xenograft model .
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- HY-D2635
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Fluorescent Dye
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Cy3 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
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- HY-D2485
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Fluorescent Dye
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Sulfo Cy3 bis COOH is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-101013
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S-Nitroso-N-acetylpenicillamine
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Fluorescent Dye
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D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.
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- HY-D1682
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Fluorescent Dye
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NFQ1 is a non-fluorescent quencher (absorption wavelength: 474 nm), and is used for a new type of One Sample Fluorescence Resonance Energy Transfer (OS-FRET) method. OS-FRET enable measurement of unquenched donor emission in the same sample. NFQ1 shows broad absorption spectrum ensuring its utility as a dark acceptor for many donors .
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- HY-P2270Y
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Fluorescent Dye
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Phalloidin-TRITC (solution) is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
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- HY-115749A
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(Rac)-6′-Methoxyluciferin sodium
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Fluorescent Dye
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D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .
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- HY-105047
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NRL972
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Fluorescent Dye
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Fluorescein lisicol is a fluorescent-labelled bile salt and a marker of hepatic biliary transporter function. Fluorescein lisicol can be used for metabolic research .
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- HY-D1608
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Fluorescent Dye
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BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells .
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- HY-D2074
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Fluorescent Dye
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ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
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- HY-D1054
-
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Cyanine2 (iodine)
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Fluorescent Dye
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Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D2011
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Fluorescent Dye
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ATTO 565 hydrazid is a hydrazide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
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- HY-D1601
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Fluorescent Dye
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N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm . N-Aminofluorescein can be used to measure the concentration of copper ions in cells .
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- HY-D2144
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Fluorescent Dye
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|
Cy5-PEG7-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D2021
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Fluorescent Dye
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ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
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- HY-137073
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Fluorescent Dye
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Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .
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- HY-D1845
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Fluorescent Dye
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|
Cy3B is an improved variant of the Cy3 (Cyanine3) (HY-D0822) dye. Cy3 is a fluorescent dye, and its fluorescence spectrum generally falls within the green to orange wavelength range .
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- HY-W099490
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Fluorescent Dye
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Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate is a fluorescent dye that can be used for generation of chemiluminescence .
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- HY-D1894
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Fluorescent Dye
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5-Br-PAPS is a highly specific Zn 2+ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn 2+ by forming a deeply colored red Zn 2+ complex .
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- HY-P1002
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Suc-LLVY-AMC
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Fluorescent Dye
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Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
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- HY-D0819
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|
Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
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Fluorescent Dye
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|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
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- HY-U00452
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Fluorescent Dye
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|
PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase, with a λmax of 210 nm and λem of 410 nm.
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- HY-D2163
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Fluorescent Dye
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AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-DY1015
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Fluorescent Dye
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Dihydroethidium (solution) , also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
Solvent and concentration: DMSO: 5 mM
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- HY-D2039
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Fluorescent Dye
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ATTO 550 cadaverin is a cadaverine derivative of ATTO 550, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 554/576 nm.
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- HY-172284
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Fluorescent Dye
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|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
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- HY-D2520
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Fluorescent Dye
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Cy3-PEG5000-biotin is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy3-PEG5000-biotin plays an important role in the specific capture and detection of biomolecules .
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- HY-D2623
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Fluorescent Dye
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|
Cy3 HA (MW 7000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-D0814
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|
4',6-Diamidino-2-phenylindole dihydrochloride
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Fluorescent Dye
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DAPI (4',6-Diamidino-2-phenylindole) dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
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- HY-D2254
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Fluorescent Dye
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CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells .
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- HY-D1168
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Fluorescent Dye
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Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .
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- HY-D0940
-
H2DCFDA
Maximum Cited Publications
747 Publications Verification
DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate
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Fluorescent Dye
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H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) .
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- HY-D0052
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Fluorescent Dye
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5(6)-Carboxyeosin-diacetate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0721
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6-Carboxyfluorescein diacetate
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Fluorescent Dye
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6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
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- HY-D1531
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Fluorescent Dye
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4-Methyl-2-phenylchromenylium tetrafluoroborate is a fluorescent dye .
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- HY-D2146
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Fluorescent Dye
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Cy5-PEG3-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-128868J
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Fluorescent Dye
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FITC-Dextran (MW 1000) is a compound that belongs to the class of fluorescent dyes. It is often used as a tracer molecule in biomedical research to label and track cells or other biological substances. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate extracted from starch. The combination of the two creates a stable fluorescent tracer that can be observed under a microscope or quantified using specialized detection instruments.
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- HY-DY1065
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Fluorescent Dye
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CY7 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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- HY-DY1034
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Fluorescent Dye
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4-MUNANA (solution) is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
Solvent and Concentration: Sterile water: 10 mM
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- HY-100041R
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Monobromobimane (Standard)
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Fluorescent Dye
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Bromobimane (Standard) is the analytical standard of Bromobimane (HY-100041). This product is intended for research and analytical applications. Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
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- HY-D1917
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Fluorescent Dye
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ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
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- HY-D2845A
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Fluorescent Dye
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4-Arm-PEG5000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG5000-FITC can be used for fluorescent labeling and imaging .
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- HY-W010947
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Fluorescent Dye
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4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .
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- HY-W356117
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Fluorescent Dye
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C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity .
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- HY-D2912
-
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Fluorescent Dye
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|
Cys-shift probe-1 (compound 13) is a potent Cys-shift probe. Cys-shift probe-1 can improve the ion mobility of labeled peptides and be used in protein analysis .
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- HY-D1849
-
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Fluorescent Dye
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|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
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- HY-D1558
-
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Fluorescent Dye
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|
1,3,5,7-Tetramethyl-2,6-diiodo-C3-SE-BODIPYs is a fluorescent dye, and a BODIPY derivative .
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- HY-D1761
-
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Fluorescent Dye
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|
Fura-4F pentapotassium is a cell-impermeant fluorescent indicator for intracellular calcium ion measurement.
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- HY-D2842A
-
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Fluorescent Dye
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FITC-PEG1000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG1000-biotin can be used for fluorescent labeling and imaging .
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- HY-D1565
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Fluorescent Dye
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Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D1986
-
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Fluorescent Dye
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ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
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- HY-155326
-
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Fluorescent Dye
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Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-D1119C
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Fluorescent Dye
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AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.) .
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- HY-D2422A
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Fluorescent Dye
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Cy5.5-Paclitaxel is a Cy5.5 (HY-D0821) labeled Paclitaxel (HY-B0015).
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- HY-D0933
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Fluorescent Dye
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Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria .
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- HY-D2667
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Fluorescent Dye
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Cy5.5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
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- HY-D2697
-
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Fluorescent Dye
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Cy7.5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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- HY-W800807
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Fluorescent Dye
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R6G azide, 5-isomer is a xanthene dye with a terminal azide. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
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- HY-D1592
-
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Fluorescent Dye
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BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
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- HY-D2054
-
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Fluorescent Dye
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ATTO 532 alkin is an alkyne derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm. ATTO 532 alkin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-100575R
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Acriflavinium chloride 3,6-Acridinediamine mix (Standard)
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Fluorescent Dye
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Acriflavine (Standard) is the analytical standard of Acriflavine (HY-100575). This product is intended for research and analytical applications. Acriflavine (Acriflavinium chloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine is an antiseptic agent. Acriflavine is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2 .
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- HY-D0152
-
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Fluorescent Dye
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|
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
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- HY-176031
-
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Fluorescent Dye
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Fluo-2 potassium is a cell-impermeant fluorescent calcium indicator. Fluo-2 potassium binds calcium (Kd: 0.37 μM) with excitation/emission wavelengths of 493/518 nm, respectively .
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- HY-D1119
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Fluorescent Dye
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AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
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- HY-139337
-
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|
Fluorescent Dye
|
|
SMCy5.5 is a SMCy dye (ex. 638 nm; em. 705 nm). The high brightness of SMCy5.5 allows for effective tracking and imaging of lipid droplet exchange between adipocytes. SMCy5.5 can be used for lipid droplet labeling studies .
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- HY-D0091
-
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Fluorescent Dye
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7-Ethoxy-4-trifluoromethylcoumarin is a fluorescent substrate of various enzymes of the cytochrome P450 superfamily
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- HY-W179417
-
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Fluorescent Dye
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|
Methacrolein-2,4-dinitrophenylhydrazone is a small molecule azo and nitro dye .
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- HY-DY1062
-
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Fluorescent Dye
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Cy5.5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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- HY-D1880
-
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Fluorescent Dye
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|
Sulfo-Cy5 hydrazide is a fluorescent dye containing a hydrazide functionality (Ex/Em=646/662 nm) .
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- HY-D2017
-
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Fluorescent Dye
|
|
ATTO 550 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 554/576 nm.
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- HY-137845
-
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Fluorescent Dye
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|
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .
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- HY-D2511
-
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Fluorescent Dye
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|
Cy3-PEG3400-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG3400-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-W739603
-
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Fluorescent Dye
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|
Cy5-bifunctional dye potassium is a water soluble bifunctional dye possessing two terminal NHS ester functions. The NHS esters can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.
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- HY-D2223
-
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Fluorescent Dye
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|
Sulfo-Cy5 dUTP is a modified nucleoside triphosphate used for DNase labeling. Sulfo-Cy5 dUTP is a bright far-red emitting dye for the Cy5 channel .
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- HY-D3448
-
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Fluorescent Dye
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|
8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .
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- HY-D1737
-
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Fluorescent Dye
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|
RADA is a fluorescent D-amino acid (FDAA) with high photostability and thermostability, which emits yellow-to-orange fluorescence. RADA shows low outer membrane permeability in wild-type Gram-negative Escherichia coli, but it targets penicillin-binding proteins and L,D-transpeptidases, mimics the interaction between acyl acceptors and enzyme intermediates, and integrates into peptidoglycan during biosynthesis. As a peptidoglycan labeling reagent, RADA metabolically integrates into the nascent peptidoglycan of live bacterial cells, labels the peptidoglycan at the poles and lateral walls of mycobacteria, and enables visualization of peptidoglycan synthesis and remodeling processes. RADA serves as a non-specific stain for fixed cells, is non-toxic to bacterial cells, and its red-shifted excitation/emission spectra reduce phototoxicity. RADA also supports virtual pulse-chase labeling experiments and stochastic optical reconstruction microscopy for sub-diffraction-limited imaging of bacterial cell walls .
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- HY-D2151
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Fluorescent Dye
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|
AF 430 hydrazide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 hydrazide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-D2145
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Fluorescent Dye
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Cy5-PEG2-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D2106
-
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Fluorescent Dye
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|
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2436
-
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Fluorescent Dye
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|
PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .
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- HY-101883
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Fluorescent Dye
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|
BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. BCECF-AM could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
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- HY-D2048
-
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Fluorescent Dye
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|
ATTO 532 streptavidin is a streptavidin derivative of ATTO 532, it can label protein or antibody, the maximum excitation/emission wavelength: 532/552 nm.
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- HY-D0259
-
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Erythrosin extra bluish
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Fluorescent Dye
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|
Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
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- HY-W090090
-
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Pyrromethene 546
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Fluorescent Dye
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|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
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- HY-101892R
-
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Fluorescent Dye
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|
DiBAC4(3) (Standard) is the analytical standard of DiBAC4(3) (HY-101892). This product is intended for research and analytical applications. DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4(3) can be used to measure cell membrane potential.
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- HY-D2227
-
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Fluorescent Dye
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|
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .
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- HY-W440914
-
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Fluorescent Dye
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|
DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.
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- HY-W027544
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7-Methoxycoumarin-4-acetic acid
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Fluorescent Dye
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MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .
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- HY-D1353
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Fluorescent Dye
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LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish .
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- HY-D2486
-
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Fluorescent Dye
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|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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- HY-D1365A
-
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Fluorescent Dye
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|
Sulfo-Cy3(Me)COOH TEA is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .
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- HY-D1686B
-
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Fluorescent Dye
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|
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .
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- HY-D1641
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Fluorescent Dye
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|
5,5'-Dimethyl BAPTA tetrapotassium is a water-soluble, extracellular membrane metal chelator with relative selectivity for calcium ions .
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- HY-D1433
-
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|
Fluorescent Dye
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|
FITC-C6-LEHD-FMK, a fluorescently labeled caspase-9 inhibitor, can be used for detection of active caspase-9 in mammalian cells undergoing apoptosis. FITC-C6-LEHD-FMK provides a convenient means for sensitive detection of activated caspase-9 in living cells. Z-LEHD-FMK is a specific caspase-9 inhibitor .
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- HY-145385
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Fluorescent Dye
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|
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca 2+, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .
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- HY-R04602F
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Fluorescent Dye
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|
FAM-MicroRNA Mimic Negative Control is a FAM labeled FAM-MicroRNA Mimic Negative Control (HY-R04602). MicroRNA Mimic Negative Control is a miRNA mimic of 21-nucleotides, and can be used as a negative control. The sequence of MicroRNA Mimic Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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- HY-D1082
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Fluorescent Dye
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|
5-DTAF is a fluorescein dye that directly react with polysaccharides and other alcohols in aqueous solution at pH ＞9. The maximum of the 5-DTAF emission profile is at a wavelength of 518 nm after excitation at 488 nm. 5-DTAF can be used for biomolecular labeling, protein detection, and cell imaging .
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- HY-D1633
-
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Fluorescent Dye
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|
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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- HY-D2795
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Fluorescent Dye
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|
FITC-PEG400-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG400-COOH can be used for fluorescent labeling and imaging .
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- HY-126831
-
SBFI-AM
3 Publications Verification
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Fluorescent Dye
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|
SBFI-AM is a Na + selective fluorescent indicator. SBFI-AM shows selectivity for Na + over K + with Kd values of 6.7 and 166 mM, respectively (Ex = 340/380 nm; Em = 500 nm) .
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- HY-W878943
-
- HY-D2740
-
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Fluorescent Dye
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|
ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
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- HY-D1628
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Fluorescent Dye
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Calcium Green BAPTA-2 AM is a fluorescent calcium indicator.
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- HY-W800769
-
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Fluorescent Dye
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BP Fluor 532 Azide Plus is a fluroescent agent with a terminal azide group. The fluroescent compound has a max absorption at 532 nm and emission at 554 nm. The BP Fluor 532 Azide Plus was designed with a copper-chelating system within its structure, enabling the formation of strong, active copper complexes that act as both reactant and catalyst in CuAAC reactions.
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- HY-P1004
-
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Fluorescent Dye
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Luciferase (bacterial) catalyzes the oxidation of a long-chain aldehyde and reduced flavin mononucleotide. Luciferase (bacterial) protection against oxidative stress for bacterial luminescence .
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- HY-D1695
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Fluorescent Dye
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LYCBX is a neuronal tracer, a fluorescent biotin derivative of Lucifer Yellow .
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- HY-D2069
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Fluorescent Dye
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ATTO 680 alkin is an alkyne derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
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- HY-D0214R
-
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Fluorescent Dye
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Acid Red 94 sodium (Standard) is the analytical standard of Acid Red 94 sodium. This product is intended for research and analytical applications. Acid Red 94 sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Acid Red 94 sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antiviral activities .
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- HY-137098
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Fluorescent Dye
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Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
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- HY-D2618
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Fluorescent Dye
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ICG PEG2000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG2000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).
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- HY-110250
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Fluorescent Dye
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DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
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- HY-D2176
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Fluorescent Dye
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AF 555 carboxylic acid is a derivative of the orange fluorescent dye AF 555. AF 555 carboxylic acid is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 555 exhibits average excitation wavelengths under green laser and red laser of 510 nm and 610 nm, respectively .
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- HY-D1934
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Fluorescent Dye
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ATTO 465 is a new fluorescent dye with good photostability and maximum excitation/emission wavelength: 453/506 nm.
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- HY-D2414
-
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Fluorescent Dye
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SCOTfluor-89 is a small, conjugatable, orthogonal and multi-colored fluorophores for in vivo imaging of cell metabolism .
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- HY-131023
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JF549, Maleimide TFA
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Fluorescent Dye
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Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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- HY-D2080
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Fluorescent Dye
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ATTO 665 iodacetamid is an iodoacetamide derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
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- HY-D2562
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Fluorescent Dye
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Cy5.5-PEG5000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2845
-
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Fluorescent Dye
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|
4-Arm-PEG2000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG2000-FITC can be used for fluorescent labeling and imaging .
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- HY-132263
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Fluorescent Dye
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FAM hydrazide, 5-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
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- HY-100045
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4-Nitrophenylphosphorylcholine; 4-Nitrophenylphosphorylcholine; O-(4-Nitrophenylphosphoryl)choline
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Fluorescent Dye
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p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5.
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- HY-D1067
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Fluorescent Dye
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NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .
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- HY-D1503
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- HY-D2820
-
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Fluorescent Dye
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Chitosan-Cy7.5 (MW 75000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 75000) can be used for fluorescent labeling and imaging .
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- HY-118320
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Mordant orange 1
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Fluorescent Dye
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Alizarine Yellow R (Mordant orange 1), Salicylic acid derivative (HY-B0167), is an azo dye. Alizarine Yellow R is used as a pH indicator and a biological stain in chemical examinations and dyeing industries .
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- HY-B0883
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Fluorescent Dye
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3,6-Diaminoacridine hemisulfate is a multifunctional acridine compound. 3,6-Diaminoacridine hemisulfate is an acridine dye and also a DNA inserter. 3,6-Diaminoacridine hemisulfate is a potent broad-spectrum antibacterial agent. Its mechanism is to insert into bacterial DNA, interfering with replication and transcription, leading to bacterial lysis. 3,6-Diaminoacridine hemisulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine hemisulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus. Long-term exposure may induce skin cancer or other malignant tumors .
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- HY-D0785
-
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4-Fluoro-7-nitrobenzofurazan
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Fluorescent Dye
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|
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines .
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- HY-D2494
-
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Fluorescent Dye
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Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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- HY-DY1027
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Fluorescent Dye
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Indocyanine green (Foxgreen) (solution) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .
Solvent and concentration: DMSO: 10 mM
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- HY-D2482
-
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APG-1 AM
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Fluorescent Dye
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Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K +-sensitive fluorescent indicator and potassium ion indicator that exhibits minimal interference from Na + and pH at physiologically relevant intracellular levels. Asante potassium green-1 AM enables non-invasive monitoring and quantitative analysis of intracellular potassium ion concentration (ᵢ) . Its excitation/emission maxima are 525/545 nm, respectively.
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- HY-D2653
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Fluorescent Dye
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|
Cy5 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
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- HY-D2685
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Fluorescent Dye
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Cy7 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D0150A
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Fluorescent Dye
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(Z)-Thiazole Orange iodide is an asymmetric cyanine dye whose fluorescence highly depends on the local environment.(Z)-Thiazole Orange iodide is essentially dark in solution; however, its fluorescence increases a thousandfold when (Z)-Thiazole Orange iodide is introduced into double-stranded DNA and RNA (dsDNA or dsRNA). The maximum absorption of Thiazole Orange in complex with DNA is 509 nm, and the maximum emission is 532 nm. Thiazole Orange solution is widely used for determining the percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.
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- HY-135835
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Fluorescent Dye
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6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide . 6-FAM-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1943
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Fluorescent Dye
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ATTO 590 Amine is an amine derivative of ATTO 590, the maximum excitation/emission wavelength: 594/622 nm.
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- HY-D2015
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Fluorescent Dye
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ATTO 488 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 alkyne is an alkyne derivative of ATTO 488 and can be used to label proteins or antibodies.
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- HY-15944
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5(6)-Carboxytetramethylrhodamine
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Fluorescent Dye
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5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).
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- HY-D1114
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Fluorescent Dye
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|
TFAX 488,SE dilithium is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,SE dilithium yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
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- HY-D2081
-
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Fluorescent Dye
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ATTO 665 alkin is an alkyne derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
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- HY-D2250
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Fluorescent Dye
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|
Disulfo-ICG carboxylic acid is a derivative of ICG dye. ICG (Indocyanine Green) is a NIR fluorescent dye .
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- HY-D2531
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Fluorescent Dye
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Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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- HY-D2681
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Fluorescent Dye
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Cy7 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D1933
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Fluorescent Dye
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ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
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- HY-155322
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Fluorescent Dye
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Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-123645
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Fluorescent Dye
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Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu 2+), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) .
Excitation/emission wavelength:
Conventional detection: 510/578 nm.
Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).
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- HY-151710
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Fluorescent Dye
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Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1322
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Fluorescent Dye
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|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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- HY-D2754
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Fluorescent Dye
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BP Light 550 acid is a vibrant orange-to-red fluorochrome with better performance t han other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light Fluors means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
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- HY-D1863
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Fluorescent Dye
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sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-100512R
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Pentacarboxybenzene (Standard)
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Fluorescent Dye
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Benzenepentacarboxylic Acid (Standard) is the analytical standard of Benzenepentacarboxylic Acid (HY-100512). This product is intended for research and analytical applications. Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.
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- HY-B1025
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Lanadigenin
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Fluorescent Dye
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|
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .
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- HY-W040291
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Fluorescent Dye
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|
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. It is widely used for preparing bioconjugates of blue fluorescence.
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- HY-D2173
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Fluorescent Dye
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|
AF488 azide is a fluorescent dye that can be used to determine the reactivity of immobilized DIBO groups. AF488 azide exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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- HY-W400925
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Fluorescent Dye
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|
Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-DY1107
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Fluorescent Dye
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Halo tag TMR (solution) is a red fluorescent dye composed of Halo tag ligand molecules and TMR (TAMRA). Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity (Ex/Em = 550/576 nm) .
Solvent and concentration: DMSO: 5 mM
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- HY-D1176
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Fluorescent Dye
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|
Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases .
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- HY-D1520
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Fluorescent Dye
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|
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .
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- HY-D3300
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Fluorescent Dye
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WSP2 (compound 7) is a turn-on fluoresonance probe that can be used for the detection of sulfane sulfur species .
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- HY-D1376A
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Fluorescent Dye
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Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
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- HY-DY1029
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Fluorescent Dye
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BODIPY-cholesterol (solution) is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
Solvent and concentration: DMSO: 1 mM
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- HY-D2801
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Fluorescent Dye
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FITC-PEG400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG400-NHS can be used for fluorescent labeling and imaging .
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- HY-D1066
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Fluorescent Dye
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|
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice .
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- HY-W998675
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Fluorescent Dye
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|
5-FITC-Tetrazine is an fluorescent dye composed of FITC (HY-66019) and Tetrazine. 5-FITC-Tetrazine can be used for fluorescent labeling and imaging .
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- HY-D1346
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Fluorescent Dye
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|
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.
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- HY-130210
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Fluorescent Dye
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|
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.
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- HY-D1374
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Fluorescent Dye
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|
Sulfo-Cy5 carboxylic acid potassium is a water-soluble, inactive Cy5 carboxylic acid.
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- HY-D0058
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Fluorescent Dye
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3,3'-Dipropylthiacarbocyanine (iodide) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-W879007
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Fluorescent Dye
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|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
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- HY-D2836B
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FITC-Hyaluronate (MW 200000)
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Fluorescent Dye
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|
FITC-HA (MW 200000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D2608
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|
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Fluorescent Dye
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|
ICG PEG10000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG10000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
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- HY-D1029
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- HY-D2108
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|
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Fluorescent Dye
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|
TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-D2798C
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Fluorescent Dye
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|
FITC-PEG10000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG10000-SH can be used for fluorescent labeling and imaging .
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- HY-D0121B
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Fluorescent Dye
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|
INDO 1 pentasodium is a cell-impermeant ratiometric, free calcium ion (Ca 2+) fluorescent indicator that can quantitatively monitor dynamic changes in intracellular free Ca 2+ concentrations. When unbound to Ca 2+ (free state), INDO 1 pentasodium exhibits a peak emission wavelength of 485 nm under UV excitation (350 nm). Upon binding to Ca 2+ (bound state), the emission peak shifts to 405 nm. INDO 1 pentasodium is highly photolabile and susceptible to photobleaching, and its emission spectrum may overlap with the autofluorescence of NADH .
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- HY-D2652
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Fluorescent Dye
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|
Cy5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
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- HY-D0073
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Fluorescent Dye
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|
2,3-Diaminonaphthalene is a fluorescent reagent used to detect selenium and nitric oxide (NO). 2,3-Diaminonaphthalene binds to selenium to form pyrazolene selenol, with excitation/emission maxima at 365 nm and 525 nm, respectively. 2,3-Diaminonaphthalene binds to NO2− to form the fluorescent product, 1-(H)-napthotriazole, with excitation/emission maxima at 360 nm and 440 nm, respectively .
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- HY-D1081
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Fluorescent Dye
|
|
6-DTAF hydrochloride is a fluorescein that can be used to label peptides and nucleotides .
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- HY-D1630
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|
|
Fluorescent Dye
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|
4-Di-10-ASP is a fluorescent lipophilic tracer (Excitation 485 nm; Emission 620 nm). 4-Di-10-ASP can be used to stain phospholipid membranes in a specific manner .
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- HY-D2680
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|
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Fluorescent Dye
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|
Cy7 HA (MW 200000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D1847
-
|
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Fluorescent Dye
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|
Cy7.5 tetrazine tetrafluoroborate is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a tetrazine group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Cy7.5 tetrazine tetrafluoroborate can perform efficient click reactions with molecules containing alkyne functional groups (such as alkyne) to form covalent bonds. It can be combined with biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D2541
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|
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Fluorescent Dye
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|
Cy5-PEG1000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D1900
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Fluorescent Dye
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|
VIC azide, 6-isomer is a VIC derivative that can be used for conjugating VIC to other molecules. VIC can be used for labeling oligonucleotides at the 5’-end .
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- HY-D0101A
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|
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Fluorescent Dye
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|
Fluorescein-diphosphat (ammonium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-151690
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|
|
Fluorescent Dye
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|
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
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- HY-D2764
-
|
|
Fluorescent Dye
|
|
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
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- HY-D2036
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Fluorescent Dye
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|
ATTO 550 iodacetamid is an iodoacetamide derivative of ATTO 550 with maximum excitation/emission wavelengths: 554/576 nm.
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- HY-D2059
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Fluorescent Dye
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ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
- HY-169130
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Fluorescent Dye
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Lyso BD-1, preferentially colocalized in lysosomes and lipid droplets, displays excellent photocytotoxicity (5.57 μM) on triple negative breast cancer cells under white light. Lyso BD-1 displays emission band at 560nm .
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- HY-D2205
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|
Cy7 TSA
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Fluorescent Dye
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Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
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- HY-D2498
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Fluorescent Dye
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Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
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- HY-D2030
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|
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Fluorescent Dye
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|
ATTO 514 streptavidin is a streptavidin derivative of ATTO 514, it can label protein or antibody, the maximum excitation/emission wavelength: 511/531 nm.
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- HY-DY1076
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|
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Fluorescent Dye
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BODIPY TR Cadaverine (solution) , a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .
Solvent and concentration: DMSO: 2 mM
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- HY-D2138
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|
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Fluorescent Dye
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|
Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-DY1022
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|
|
Fluorescent Dye
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BODIPY 581/591 C11 (solution) is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype) , or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .
Solvent and concentration: DMSO: 2 mM
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- HY-D2058
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|
|
Fluorescent Dye
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|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
- HY-D2854E
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|
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Fluorescent Dye
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|
FITC-PEG10000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em = 488/525 nm).
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- HY-D1376
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|
|
Fluorescent Dye
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|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
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- HY-W748361
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Fluorescent Dye
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|
Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
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- HY-D1446
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Fluorescent Dye
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3′,6′-Bis(allyloxy)-Fluoran is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1312
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|
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Fluorescent Dye
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|
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
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- HY-W320397
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Fluorescent Dye
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|
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.
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- HY-D1920
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Fluorescent Dye
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ATTO 390 azide is an azide derivative of ATTO 390 with excitation/emission maxima at 390/476 nm. ATTO 390 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-172721
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Fluorescent Dye
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Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
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- HY-151712
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Fluorescent Dye
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Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.
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- HY-D0016
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CTC
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Fluorescent Dye
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5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm .
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- HY-D2241
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Fluorescent Dye
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Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
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- HY-DY1041
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Fluorescent Dye
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CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
Solvent and concentration: DMSO: 10 mM
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- HY-DY1093
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Thioflavin S (solution); Direct Yellow 7 (solution)
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Fluorescent Dye
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Thioflavine S (solution) (Thioflavin S (solution)) is a fluorescent histochemical marker of dense core senile plaques. Thioflavine S can be used for Alzheimer's research .
Solvent and concentration: ddH2O: 10 mg/mL
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- HY-D1519
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- HY-W800702
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Fluorescent Dye
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BP Fluor 555 Azide is a water-soluble, bright orange-fluorescent dye with excitation ideally suited for the 532 nm or 555 nm laser lines and visualized with TRITC (tetramethylrhodamine) filter sets. BP Fluor 555 conjugates of antibodies, peptides, and proteins are pH insensitive from pH 4 to pH 10. AF 555 conjugates ideally suited for detection of low abundance targets.
BP Fluor 555 Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. The brightness and photostability of this dye are best suited to direct imaging of low-abundance targets.
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- HY-D2076
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Fluorescent Dye
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ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
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- HY-D1846
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Fluorescent Dye
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Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-159194
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Fluorescent Dye
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DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .
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- HY-D1980
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Fluorescent Dye
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ATTO 620 Carboxy is a carboxyl derivative of ATTO 620, the maximum excitation/emission wavelength is: 620/642 nm.
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- HY-D0122
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Fluorescent Dye
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6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .
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- HY-D1915
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Fluorescent Dye
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ATTO 390 is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy.
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- HY-D2802B
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Fluorescent Dye
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FITC-PEG3400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2329
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Fluorescent Dye
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Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
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- HY-D0135
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Fluorescent Dye
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12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye .
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- HY-172286
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Fluorescent Dye
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Cy7 NHS ester is a fluorescent dye that can be used for fluorescent imaging study.
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- HY-D0167
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Fluorescent Dye
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NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
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- HY-D2766
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Fluorescent Dye
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BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
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- HY-D0918
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Fluorescent Dye
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YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/530±30 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells .
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- HY-129547
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Fluorescent Dye
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Fluo-3 pentapotassium is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 pentapotassium itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
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- HY-D2251
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- HY-D1324
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Fluorescent Dye
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Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
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- HY-D2674
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Fluorescent Dye
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Cy7 HA (MW 7000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2761
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Fluorescent Dye
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DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
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- HY-D0121
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Fluorescent Dye
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INDO 1 is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
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- HY-D1389
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Sulfo-Cyanine5.5 NHS ester tripotassium
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Fluorescent Dye
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Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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- HY-D2592
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Fluorescent Dye
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Cy7.5-PEG1000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
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- HY-D1750
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Fluorescent Dye
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Rhodamine B thiolactone is a high-sensitive Hg 2+ indicator used for measuring Hg 2+ concentration.
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- HY-DY1064
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Fluorescent Dye
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CY5 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
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- HY-D2517
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Fluorescent Dye
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Cy3-PEG5000-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2083
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Fluorescent Dye
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BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments (Ex/Em = 540/580 nm) .
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- HY-D2238
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- HY-D1461
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Fluorescent Dye
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Fluorescein Di-β-D-Glucopyranoside is a specific β-glucocerebrosidase substrate that can be used for the intralysosomal β-galactosidase .
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- HY-175046
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Fluorescent Dye
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C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0) (Lissamine-rhodamine B-dodecanoyl Galactosylceramide) is a fluorescently labeled version of C12 galactosylceramide.
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- HY-D2622
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Fluorescent Dye
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Cy3 HA (MW 3000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-D2840A
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Fluorescent Dye
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FITC-mPEG550 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG550 can be used for fluorescent labeling and imaging .
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- HY-D2516
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Fluorescent Dye
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Cy3-PEG3400-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2198
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Fluorescent Dye
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AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
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- HY-DY1047
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Fluorescent Dye
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DFHBI-1T (solution) is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
Solvent and concentration: DMSO: 20 mM
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- HY-126774
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DAF-FM
1 Publications Verification
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Fluorescent Dye
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DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .
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- HY-101901
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Fluorescent Dye
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Oxazine 1 perchlorate is a symmetric cationic dye (λex=653 nm, λem=666 nm).
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- HY-D2121
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Fluorescent Dye
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Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D2801A
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Fluorescent Dye
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FITC-PEG1000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG1000-NHS can be used for fluorescent labeling and imaging .
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- HY-D2757
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Fluorescent Dye
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5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm.
The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
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- HY-D2552
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Fluorescent Dye
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Cy5.5-PEG1000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG1000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
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- HY-D1550
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Fluorescent Dye
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10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a fluorescent dye for Cu 2+ ion .
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- HY-D1262
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Thiol-green 2
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Fluorescent Dye
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BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols . Ex: 490 nM; Em: 515 nM.
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- HY-D2826D
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Fluorescent Dye
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FITC-Chitosan (MW 5000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 5000) can be used for fluorescent labeling and imaging .
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- HY-D145729F
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Fluorescent Dye
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FAM-Danvatirsen is a FAM-labeled Danvatirsen (HY-145729). Danvatirsen is an antisense oligonucleotide targeting STAT3 that can be used in the study of cancer .
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- HY-D1463
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Fluorescent Dye
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Nile Blue Methacrylamide is a pH-responsive probe. Nile Blue Methacrylamide exhibits pH-sensitive absorption and fluorescence emission in the physiological pH range, with spectral shifts occurring between acidic and near-physiological pH conditions . (Ex/Em = 590/670-700 nm)
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- HY-111263
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NIAD-4
1 Publications Verification
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Fluorescent Dye
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NIAD-4 is a blood-brain barrier permeable fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM .
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- HY-147114
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Fluorescent Dye
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3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm .
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- HY-D0092R
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Fluorescent Dye
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7-Ethoxy-4-methylcoumarin (Standard) is the analytical standard of 7-Ethoxy-4-methylcoumarin. This product is intended for research and analytical applications. 7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .
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- HY-131461
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- HY-D0981
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Coumarin 151; AFC
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Fluorescent Dye
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7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.
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- HY-D2020
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Fluorescent Dye
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ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
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- HY-D2709
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Fluorescent Dye
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Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-D2800A
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Fluorescent Dye
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FITC-PEG1000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG1000-MAL can be used for fluorescent labeling and imaging .
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- HY-D1585
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Fluorescent Dye
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BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo .
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- HY-D2003
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Fluorescent Dye
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ATTO 565 biotin is a biotin derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
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- HY-D2158
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Fluorescent Dye
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Cy5-PEG7-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2582
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Fluorescent Dye
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DMAO is a membrane-permeable DNA fluorescent dye stains live and dead bacteria. (Ex/Em = 490/540 nm) .
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- HY-D2438
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Fluorescent Dye
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CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
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- HY-D1544
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Fluorescent Dye
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Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM) .
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- HY-15943
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6-TAMRA
1 Publications Verification
6-Carboxytetramethylrhodamine
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Fluorescent Dye
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6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .
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- HY-D1699
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Fluorescent Dye
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PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity .
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- HY-D0830
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Fluorexon tetraethyl ester
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Fluorescent Dye
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Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
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- HY-D2483
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APG-1 (TMA)
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Fluorescent Dye
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Asante potassium green-1 (APG-1) TMA is a cell-impermeable K + (potassium) sensitive fluorescent indicator (excitation/emission = 525/545 nm) .
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- HY-DY1036
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Fluorescent Dye
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Calcein AM (solution) , has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein) , which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
Solvent and concentration: DMSO: 2 mM
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- HY-D1606
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Fluorescent Dye
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BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with Ki values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes .
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- HY-D1762
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- HY-D1119A
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Fluorescent Dye
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AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
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- HY-D1483
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Fluorescent Dye
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3,3-Dibutylthiacarbocyanine iodide is a fluorescent dye with an excitation of 559 nm and an emission 604 nm .
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- HY-D0092
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Fluorescent Dye
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7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .
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- HY-D0044
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Fluorescent Dye
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5(6)-Carboxy-X-rhodamin N-succinimidyl ester is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1571
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Fluorescent Dye
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CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms .
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- HY-D2669
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Fluorescent Dye
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Cy5.5 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
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- HY-D2490
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Fluorescent Dye
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Sulfo Cy5.5-N3 is a Sulfo Cy5.5-azide, which is a fluorescent dye. Sulfo Cy5.5-N3 can be used in cell imagine by Click reaction. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2536
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Fluorescent Dye
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Cy5-PEG10000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2707
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Fluorescent Dye
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Cy3 Dextran (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-114491
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Fluorescent Dye
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Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF .
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- HY-W591335
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Biotin-PEG5-alcohol
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Fluorescent Dye
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Biotin-PEG5-OH (Biotin-PEG5-alcohol) is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.
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- HY-D2847B
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Fluorescent Dye
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FITC-PEG5000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
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- HY-D2854A
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Fluorescent Dye
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FITC-PEG1000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-DY1012
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Fluorescent Dye
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DiI (solution) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
Solvent and concentration: DMSO: 5 mM
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- HY-D2006
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Fluorescent Dye
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|
ATTO 565 azide is an azide derivative of ATTO 565 with excitation/emission maxima at 564/590 nm.
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- HY-D2898
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Fluorescent Dye
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Jun14157 is a fluorescence polarization probe that can specifically bind to the conserved allosteric site of enterovirus 2C proteins (Ex: 485/20; Em: 528/20). Jun14157 has Kd values of 2.3 μM, 1.4 μM, and 1.1 μM for EV-D68 2C, EV-A71 2C, and CVB3 2C, respectively. Jun14157 can be used in research related to enteroviruses .
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- HY-D1743
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- HY-D1996
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Fluorescent Dye
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ATTO 647 Biotin is a biotin derivative of ATTO 647 with maximum excitation/emission wavelengths: 630/651 nm.
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- HY-121941
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Fluorescent Dye
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Epoxy Fluor 7 is a sensitive fluorescent substrate for soluble epoxide hydrolase (sEH) that can be used for human and mouse enzymes. Epoxy Fluor 7 is hydrolyzed to yield fluorescence used for monitoring the activity of sEH.
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- HY-W800695
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Fluorescent Dye
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BP Fluor 405 DBCO is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.
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- HY-D1049
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6-((2,4-Dinitrophenyl)amino)hexanoic acid
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Fluorescent Dye
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DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
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- HY-D0982
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Fluorescent Dye
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Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
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- HY-D1684
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Fluorescent Dye
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DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λex/λem=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo .
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- HY-D0012A
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Fluorescent Dye
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Bromothymol Blue sodium salt is a pH indicator. Storage: protect from light.
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- HY-66020
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6-FITC
1 Publications Verification
6-Fluorescein Isothiocyanate
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Fluorescent Dye
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6-FITC (6-Fluorescein Isothiocyanate) is a fluorescein isomer and also serves as a fluorescent label for biomolecules (FITC isomers have similar excitation/emission wavelengths, which are 495 nm/519 nm in fluorescence detection) .
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- HY-D2826A
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Fluorescent Dye
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FITC-Chitosan (MW 40000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 40000) can be used for fluorescent labeling and imaging .
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- HY-D2426
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Fluorescent Dye
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Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron .
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- HY-D1726
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Fluorescent Dye
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8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC50 close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .
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- HY-D1119B
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Fluorescent Dye
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AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
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- HY-D2026
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Fluorescent Dye
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ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
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- HY-D2840D
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Fluorescent Dye
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FITC-mPEG2000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG2000 can be used for fluorescent labeling and imaging .
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- HY-D0924
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Sulfo-Cyanine5.5
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Fluorescent Dye
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Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D0032
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DAF-2DA
2 Publications Verification
5,6-Diaminofluorescein diacetat
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Fluorescent Dye
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DAF-2DA (5,6-Diaminofluorescein diacetat) is most widely probe for NO measurement.
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- HY-D3012
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Fluorescent Dye
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12-AS is a 9-anthracenoxy fatty acid probe. 12-AS’s fluorescence decay is not a single index, and its lifetime increases with the red shift of the emission wavelength .
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- HY-D1272
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Sulfo-Cyanine3 amine
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Fluorescent Dye
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Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-173643
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Biotin-C6:0-gm3 ammonium; N-Hexanoyl-biotin-monosialoganglioside gm3 ammonium
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Fluorescent Dye
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C6 Biotin ganglioside gm3 (d18:1/6:0) (Biotin-C6:0-gm3) ammonium is a derivative of ganglioside GM3. C6 Biotin ganglioside gm3 (d18:1/6:0) ammonium can be used to detect or immobilize ganglioside GM3 through interaction with the biotin ligand .
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- HY-D2700
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Fluorescent Dye
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Cy7.5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
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- HY-W338079
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Fluorescent Dye
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Ac-Asp-Glu-Val-Asp-pNA is a peptidic substrate of caspase-3/7 .
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- HY-D0035
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Fluorescent Dye
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MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .
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- HY-D1040A
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Cyanine 5.5 carboxylic acid chloride
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Fluorescent Dye
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Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis .
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- HY-DY1039
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Fluorescent Dye
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DiBAC4 (3) (solution) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). DiBAC4 (3) can be used to measure cell membrane potential.
Solvent and concentration: DMSO: 10 mM
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- HY-D1861
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Fluorescent Dye
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Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-101889
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Oxazine 9 perchlorate
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Fluorescent Dye
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Cresyl Violet perchlorate is a red fluorescent stain, which can be used to stain neurons.
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- HY-D2174
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Fluorescent Dye
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AF488 amine is a bright, green-fluorescent dye used for labeling molecule such as antibodies. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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- HY-D1473
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Fluorescent Dye
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2-(2-Benzoxazolyl)phenyl benzoate is a photoactivated fluorescent dye .
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- HY-D2654
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Fluorescent Dye
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Cy5 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
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- HY-D0968B
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Cyanine3 triethylamine
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Fluorescent Dye
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Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
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- HY-D2112
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Fluorescent Dye
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TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1482A
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Fluorescent Dye
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Sulfo Cy5-tetrazine sodium is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine sodium is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-D1956
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Fluorescent Dye
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ATTO 594 Alkin is an alkyne derivative of ATTO 594 with maximum excitation/emission wavelengths: 603/626 nm.
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- HY-D1676
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Fluorescent Dye
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Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum .
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- HY-D2508
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Fluorescent Dye
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Cy3-PEG10000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG10000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
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- HY-D2388
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Fluorescent Dye
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Sulfo Cy5.5-hydrazide is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-D2760
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Fluorescent Dye
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BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
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- HY-D1987
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Fluorescent Dye
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ATTO 620 Streptavidin is a streptavidin derivative of ATTO 620, it can label protein or antibody, the maximum excitation/emission wavelength: 620/642 nm.
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- HY-D2062
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Fluorescent Dye
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ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
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- HY-D1629
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Fluorescent Dye
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Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles .
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- HY-W415108
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Fluorescent Dye
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10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate is an acridinium ester that produces fluorescent 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfate, and other oxidants under alkaline conditions. 10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate can be used in chemiluminescent assays, enzyme, antigen, antibody, and hormone immunoassays, and for the detection of oxidants in environmental, biological, and pharmaceutical samples .
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- HY-DN0194F
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Fluorescent Dye
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Cy3-Asiatic acid is a fluorescent labeling reagent that combines Cy3 (HY-D0822) and Asiatic acid (HY-N0194). Cy3-Asiatic acid can be used to observe and track Asiatic acid under fluorescence microscopy (Ex/Em = 550/570 nm).
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- HY-D1098
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Fluorescent Dye
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SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .
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- HY-D2875
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Fluorescent Dye
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5-FITC tyramide is a green fluorescent dye composed of FITC (HY-66019) and tyramide (Ex=488 nm, Em=525 nm). 5-FITC tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .
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- HY-D0983
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- HY-D2656
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Fluorescent Dye
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Cy5.5 HA (MW 3000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-W440914B
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Fluorescent Dye
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DSPE-PEG10000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG10000-FITC can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers .
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- HY-D2738
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Fluorescent Dye
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BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
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- HY-D2045
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Fluorescent Dye
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ATTO 532 carboxy is a carboxyl derivative of ATTO 532, the maximum excitation/emission wavelength is: 532/552 nm.
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- HY-D2179
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Fluorescent Dye
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AF 568 DBCO is a fluorescent dye that reacts with azide-labeled molecules or biomolecules via copper-free click chemistry. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
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- HY-D1574
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Fluorescent Dye
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C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
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- HY-D2750
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Fluorescent Dye
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Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
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- HY-D0226
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1,4-Dihydroxyanthraquinone
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Fluorescent Dye
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Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .
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- HY-D2651
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Fluorescent Dye
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Cy5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
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- HY-D2014
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Fluorescent Dye
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ATTO 565 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 alkyne is an alkyne derivative of ATTO 565 and can be used to label proteins or antibodies.
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- HY-D2168
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Fluorescent Dye
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AF 568 azide is an azide derivative of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Azide group and molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-D2763
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Fluorescent Dye
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BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
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- HY-136277
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DFHO
1 Publications Verification
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Fluorescent Dye
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DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells .
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- HY-D1118
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Fluorescent Dye
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BODIPY 576/589 is a long wavelength biological labeled dye contains a free COOH-group (Em/Ex = 589/576 nm) .
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- HY-D1746
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EDTA-AM
2 Publications Verification
EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
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Fluorescent Dye
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EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .
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- HY-D0107
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Fluorescent Dye
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Fluorescein dicaproate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
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- HY-D0936
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Fluorescent Dye
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SPQ is a fluorescent dye. SPQ can be used to measure chloride ion concentration transients and transport rates in vesicles, cells, and even intact epithelium .
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- HY-135239
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Fluorescent Dye
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Fura-FF pentapotassium is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration) .
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- HY-D2816
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Fluorescent Dye
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Chitosan-Cy7.5 (MW 2000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 2000) can be used for fluorescent labeling and imaging .
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- HY-107864R
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Tetraiodofluorescein (Standard)
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Fluorescent Dye
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Erythrosine B free acid (Standard) is the analytical standard of Erythrosine B (free acid) (HY-107864). This product is intended for research and analytical applications. Erythrosine B free acid is a visibly red dye with colorimetric and fluorescent properties that serves as an important dye for many Gram-positive and -negative bacteria. Erythrosine B free acid can be used for live/dead determination in both colorimetric and fluorescence-based assays for low, medium and high-throughput experimentation .
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- HY-D2798B
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Fluorescent Dye
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FITC-PEG5000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG5000-SH can be used for fluorescent labeling and imaging .
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- HY-D1588
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Fluorescent Dye
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BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .
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- HY-D0367
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Calcofluor White M2R
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Fluorescent Dye
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Fluorescent brightener 28 is a fluorescent whitening agent commonly used in the padding process of the textile industry. Fluorescent brightener 28 is capable of staining polysaccharides such as cellulose, and when the plasma membrane ruptures, it also weakly stains the cytoplasm and strongly stains the cell nucleus. Additionally, Fluorescent brightener 28 can be utilized to detect intracellular chitin in living cells. Fluorescent Brightener 28 also is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .
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- HY-D0036
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4-Bromomethyl-7-methoxycoumarin
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Fluorescent Dye
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Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is often used as fluorescent label for the determination of compounds possessing a carboxylic group. Br-Mmc is used for the determination fatty acids by TLC or HPLC .
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- HY-D0110A
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Fluorescent Dye
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Fura-2 pentapotassium is a cell-impermeable scaled fluorescent dye that can be used for intracellular calcium imaging. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca 2+ level .
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- HY-D3315
-
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Fluorescent Dye
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|
Rhodamine B carbohydrazide is a fluorescent derivative based on Rhodamine B (HY-Y0016) that contains the spirocyclic structure of Rhodamine B; it can be used for the detection of copper ions (Cu 2+), mercury ions, peroxynitrite, hydroxyl radicals, and nitric oxide (NO).
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- HY-W297715
-
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|
Fluorescent Dye
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|
7-Acetoxy-4-bromomethylcoumarin acts as a fluorescence label for fatty acids.
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- HY-D2558
-
|
|
Fluorescent Dye
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Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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- HY-D2035
-
|
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Fluorescent Dye
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|
ATTO 514 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 alkyne is an alkyne derivative of ATTO 514 and can be used to label proteins or antibodies.
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- HY-D1755
-
|
|
Fluorescent Dye
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|
Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca 2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg 2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.
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- HY-101937B
-
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Fluorescent Dye
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|
L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
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- HY-D1332
-
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Fluorescent Dye
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BODIPY FL hydrazide hydrochloride is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-110213
-
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Fluorescent Dye
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BODIPY 630/650X is a red fluorescent dye that targets amine groups. BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively. BODIPY 630/650X can be used to covalently label proteins, antibodies, or other amine-containing biomolecules for detection and imaging .
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- HY-D1926
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Fluorescent Dye
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ATTO 425 Streptavidin is a streptavidin derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
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- HY-D2264
-
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Fluorescent Dye
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|
Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices .
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- HY-151537
-
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Fluorescent Dye
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|
Gol-NTR is a Golgi-targetable probe with high selectivity and sensitivity. Gol-NTR is Nitroreductase (NTR)-activated and has visualization acute lung injury (ALI) and repair function. Gol-NTR has a low detection limit of 54.8 ng/mL. Gol-NTR can be used for the research for monitoring and assessing research response of sepsis-induced ALI .
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- HY-D1543
-
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Fluorescent Dye
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|
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor .
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- HY-D1598
-
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Fluorescent Dye
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|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D1864
-
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Fluorescent Dye
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Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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- HY-D2854B
-
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|
Fluorescent Dye
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FITC-PEG2000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-D0108
-
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Fluorescent Dye
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|
Fluorescein dilaurate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
- HY-175133
-
|
Biotin ceramide (t18:0/6:0)
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Fluorescent Dye
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|
C6 Biotin phytoceramide (t18:0/6:0) is an affinity probe that allows C6 phytoceramide to be detected or immobilized through interaction with the biotin ligand .
|
- HY-D1319A
-
|
Cy5 acid bromide
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Fluorescent Dye
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|
Cyanine5 carboxylic acid (bromide) is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm). Cyanine5 carboxylic acid chloride is an non-reactive dye that can be used in control samples .
|
- HY-66022
-
5-FAM
4 Publications Verification
5-Carboxyfluorescein
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Fluorescent Dye
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|
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .
|
- HY-147171
-
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Fluorescent Dye
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|
2,7-Bis(alloxycarbonylamino)-9-chloroacridine can be used as a fluorescent label.
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- HY-D1250
-
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Fluorescent Dye
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|
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
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- HY-D2489
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Fluorescent Dye
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Cy5-tetrazine is a fluorescent dye. Cy5-tetrazine is a CY5 (HY-D0821) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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- HY-D2002
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Fluorescent Dye
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ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
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- HY-136865
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Fluorescent Dye
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|
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm) .
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- HY-D0022A
-
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6-AF
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Fluorescent Dye
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|
6-Aminofluorescein (6-AF) is a fluorescent labeling reagent. 6-Aminofluorescein can be used to label fullerene-based liposome nanostructures termed ‘buckysomes′ (Ex/Em = 490/515 nm) .
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- HY-D2103
-
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Fluorescent Dye
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|
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
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- HY-D0397
-
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Fluorescent Dye
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C.I. Direct Violet 9 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1562
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Fluorescent Dye
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|
CytoTrace Red CMTPX is a cell permeable long-term cell tracer (Ex=577 nm, Em=602 nm) .
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- HY-D2047
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Fluorescent Dye
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ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
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- HY-D1586
-
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Fluorescent Dye
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|
Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
|
- HY-124013
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4-(α-N-L-alanine)-NBD
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Fluorescent Dye
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|
NBDA (4-(α-N-L-alanine)-NBD) is a structural and functional analogue of the 2,4-dinitrophenyl group (DNP). NBDA can be used to detect and characterize antinitroaromatic antibodies, even in crude preparations, and possibly on cell surfaces .
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- HY-D2278
-
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Fluorescent Dye
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|
GDP-Fucose-Cy5 is a fluorescent dye that can be used for labeling free glycans, glycoproteins and glycolipids .
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- HY-D1050
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6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
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Fluorescent Dye
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DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
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- HY-D2248
-
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Fluorescent Dye
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|
ICG-TCO is a fluorescent dye coupled by Indocyanine Green (ICG) and TCO. ICG-TCO can be used for detection and visualization of tetrazine-containing molecules.
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- HY-D2800C
-
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Fluorescent Dye
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|
FITC-PEG5000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG5000-MAL can be used for fluorescent labeling and imaging .
|
- HY-DY1031
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Fluorescent Dye
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FM4-64 (solution) is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM4-64 is widely used in endocytic and exospic membrane structure markers.
Solvent and concentration: DMSO: 5 mM
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- HY-103470
-
|
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Fluorescent Dye
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|
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .
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- HY-D1913
-
|
|
Fluorescent Dye
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|
Fe2Orange is a Fe 2+ selective probe with an excitation wavelength of 543 nm and an emission wavelength of 580 nm. Fe2Orange emits fluorescence after binding to intracellular Fe 2+, thereby achieving specific labeling of Fe 2+. Fe2Orange is used to detect the content and distribution of Fe 2+ in cells .
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- HY-D2016
-
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Fluorescent Dye
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|
ATTO 565 cadaverine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 cadaverine is a cadaverine derivative of ATTO 565, which can be used to label proteins or antibodies.
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- HY-W923132
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|
Acryloyloxy fluorescein
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Fluorescent Dye
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|
Fluorescein O-acrylate (Acryloyloxy fluorescein) is a highly efficient fluorescent monomer that exhibits strong quantum yield in aqueous solutions, with its excitation and emission wavelengths situated within the visible light spectrum. This versatile monomer can be copolymerized with various compounds, including styrene, and acrylamide, enhancing its ability to bond with macromolecules.
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- HY-D1953
-
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Fluorescent Dye
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|
ATTO 594 Azide is an azide derivative of ATTO 594 with excitation/emission maxima at 603/626 nm.
|
- HY-W806655
-
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Fluorescent Dye
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|
Cy3.5 carboxylic acid is a fluorophore featuring a carboxylic acid. The carboxylic acid is readily attacked by amines to form a stable amide bond. Cy3.5 is a cyanine dye with excitation and emission maxima at 576 nm and 603 nm respectively.
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- HY-D1730A
-
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|
Fluorescent Dye
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|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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- HY-D2005
-
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|
Fluorescent Dye
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|
ATTO 565 amine is an amine derivative of ATTO 565, the maximum excitation/emission wavelength: 564/590 nm.
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- HY-120971
-
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DepNA
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Fluorescent Dye
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|
N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DepNA to FAAH activity results in the release of the yellow colorimetric dye p-nitroaniline (ε=13,500 at 410 nm). This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer.
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- HY-W127769
-
|
Salmon-Gal
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Fluorescent Dye
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|
Rose-β-D-Gal is a chromogenic substrate, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity .
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- HY-D2553
-
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|
Fluorescent Dye
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|
Cy5.5-PEG3400-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG3400-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-101887R
-
|
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Fluorescent Dye
|
|
Calcein Blue (Standard) is the analytical standard of Calcein Blue (HY-101887). This product is intended for research and analytical applications. Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator .
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- HY-D1959
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|
Fluorescent Dye
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|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
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- HY-D2117
-
|
|
Fluorescent Dye
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|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D1866
-
|
|
Fluorescent Dye
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|
Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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- HY-D2200
-
|
|
Fluorescent Dye
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|
Cy5.5(Me)-C3-DBCO is a click chemistry reagent containing an cycloalkynes group. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .
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- HY-D1739
-
|
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Fluorescent Dye
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|
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.
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- HY-D2854D
-
|
|
Fluorescent Dye
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|
FITC-PEG5000-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-143285
-
|
|
Fluorescent Dye
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|
AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
|
- HY-D1937
-
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Fluorescent Dye
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|
ATTO 465 Streptavidin is a streptavidin derivative of ATTO 465, the maximum excitation/emission wavelength: 453/506 nm.
|
- HY-D2569
-
|
|
Fluorescent Dye
|
|
Cy5.5-PEG2000-Biotin is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5.5-PEG2000-Biotin plays an important role in the specific capture and detection of biomolecules.
|
- HY-D1469
-
|
R6G-SE
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Fluorescent Dye
|
|
5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye .
|
- HY-D0233R
-
|
|
Fluorescent Dye
|
|
Leucocrystal violet (Standard) is the analytical standard of Leucocrystal violet (HY-D0233). This product is intended for research and analytical applications. Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.
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- HY-D1939
-
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|
Fluorescent Dye
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|
ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
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- HY-D1936
-
|
|
Fluorescent Dye
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|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
- HY-172269
-
|
|
Fluorescent Dye
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|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
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- HY-D1871
-
|
|
Fluorescent Dye
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|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-D2434
-
|
|
Fluorescent Dye
|
|
HRP-PEG-Cy3 is a HRP and Cy3 (HY-D0822) labeled PEG. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm.
|
- HY-D2244
-
|
|
Fluorescent Dye
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|
Cy3 phosphoramidite?is a fluorescent dye for oligonucleotide labeling.
|
- HY-D1997
-
|
|
Fluorescent Dye
|
|
ATTO 665 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 663/680 nm.
|
- HY-D2670
-
|
|
Fluorescent Dye
|
|
Cy5.5 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
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- HY-D1967
-
|
|
Fluorescent Dye
|
|
ATTO 633 Azide is an azide derivative of ATTO 520 with excitation/emission maxima at 630/651 nm.
|
- HY-D1053
-
|
Sulfo-Cyanine7-N3
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Fluorescent Dye
|
|
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-W879342
-
- HY-D1337
-
|
|
Fluorescent Dye
|
|
Cyanine7 carboxylic acid chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-DY1049
-
|
|
Fluorescent Dye
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Thioflavin T (solution) is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) .
Solvent and Concentration: Sterile water: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D1905
-
|
|
Fluorescent Dye
|
|
ICG acid is a fluorescent dye used in medical diagnostics. ICG acid has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue. ICG acid has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors .
|
- HY-135414
-
|
|
Fluorescent Dye
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-D1577
-
|
|
Fluorescent Dye
|
|
C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research .
|
- HY-D2208
-
|
|
Fluorescent Dye
|
|
SYTM Green is a cell impermeant DNA dye that fluoresces green by binding to dsDNA (Ex/Em=503/530 nm). SYTM Green can also be used to stain bacteria, including Gram-positive and Gram-negative bacteria. Note: SYTM Green cannot penetrate living cells, and this product is equivalent to (Ex/Em=488/530 nm) .
|
- HY-136936
-
|
|
Fluorescent Dye
|
|
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
|
- HY-D1897
-
|
5′-Tetrachlorofluorescein phosphoramidite
|
Fluorescent Dye
|
|
6-TET phosphoramidite (5′-Tetrachlorofluorescein phosphoramidite) is a fluorescent dye that can be used for labeling an oligonucleotide with fluorescein .
|
- HY-W027773
-
|
MFC
|
Fluorescent Dye
|
|
7-Methoxy-4-(trifluoromethyl)coumarin (MFC) is a fluorescent substrate for cytochrome P450 and can quantify CYP activity .
|
- HY-172285
-
|
|
Fluorescent Dye
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|
Cy3 hydrazide is a cyanine dye linker containing hydrazide, which can be used to label aldehydes and ketones. This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins after oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
|
- HY-D2710
-
|
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Fluorescent Dye
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Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-W127716
-
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Fluorescent Dye
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|
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
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- HY-D2858
-
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Fluorescent Dye
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|
8-Arm-PEG10000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-Arm-PEG10000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
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- HY-D2291
-
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Fluorescent Dye
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|
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
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- HY-D2614
-
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Fluorescent Dye
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|
ICG PEG2000 biotin is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em=785/813 nm).
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- HY-D2842D
-
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Fluorescent Dye
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|
FITC-PEG5000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG5000-biotin can be used for fluorescent labeling and imaging .
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- HY-P2270
-
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Fluorescent Dye
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|
Phalloidin-TRITC is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
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- HY-D1044
-
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Rhodamine 640 chloride
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Fluorescent Dye
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Rhodamine 101 chloride (Rhodamine 640 chloride) is a fluorescent dye with excitation and emission maxima at 565 nM and 595 nM, respectively. Rhodamine 101 chloride binds to intracellular proteins and emits specific fluorescence. Rhodamine 101 chloride can be used in colon cancer research .
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- HY-D1052
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Fluorescent Dye
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Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D1442
-
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Fluorescent Dye
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SBFI (tetraammonium), the tetraammonium salt of SBFI, is a cell-impermeant sodium fluorescence indicator. SBFI (tetraammonium) is sodium-sensitive dye. The excitation wavelength is set 333 nm, and the emission wavelength is 539 nm for SBFI .
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- HY-D2745
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Fluorescent Dye
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BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
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- HY-D2161
-
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Fluorescent Dye
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|
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-134435
-
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Fluorescent Dye
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|
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
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- HY-D2111
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Fluorescent Dye
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TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D0718
-
|
Nile Blue A oxazone; Phenoxazone 9
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Fluorescent Dye
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Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm .
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- HY-D1316
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Fluorescent Dye
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Cyanine7 azide chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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- HY-158741
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APG-2 Acetoxymethyl ester
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Fluorescent Dye
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IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .
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- HY-D2655
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Fluorescent Dye
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Cy5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
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- HY-D1969
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Fluorescent Dye
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ATTO 700 Alkin is an alkyne derivative of ATTO 700 with maximum excitation/emission wavelengths: 700/716 nm. ATTO 700 Alkin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2140
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Fluorescent Dye
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Cy3-PEG4-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 4 PEG units. Cy3-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D0059
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DIB-Cl
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Fluorescent Dye
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4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC .
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- HY-D0081A
-
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Fluorescent Dye
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5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin is a fluorescent indicator for NO .
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- HY-D0399
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Fluorescent Dye
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C.I. Acid blue 40 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2497
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Fluorescent Dye
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Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
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- HY-114879
-
DDAO
1 Publications Verification
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Fluorescent Dye
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DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
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- HY-D2504
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- HY-D2429
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Fluorescent Dye
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Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
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- HY-D1962
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Fluorescent Dye
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ATTO 633 Streptavidin is a streptavidin derivative of ATTO 633, it can label protein or antibody, the maximum excitation/emission wavelength: 630/651 nm.
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- HY-126839
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5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
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Fluorescent Dye
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C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
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- HY-D2165
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Fluorescent Dye
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AF 594 streptavidin is a bioconjugating agent. It consists of AF 594 and streptomycin, a streptomycin derivative of the red fluorescent dye AF 594. AF 594 has high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 streptavidin can be selectively conjugated to streptavidin-modified molecules via a streptomycin-modifying group for fluorescent labeling and spectroscopic analysis .
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- HY-D2031
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Fluorescent Dye
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ATTO 514 biotin is a biotin derivative of ATTO 514 with maximum excitation/emission wavelengths: 511/531 nm.
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- HY-D1112
-
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Fluorescent Dye
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TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies .
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- HY-D2599
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Fluorescent Dye
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ICG PEG1000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG1000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
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- HY-D2118
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Fluorescent Dye
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TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D0162
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MCCK1
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Fluorescent Dye
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Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo .
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- HY-W248587
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- HY-D2538
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Fluorescent Dye
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Cy3-PEG3400-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1885
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Fluorescent Dye
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|
Vari Fluor 647 Carboxylic acid free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivative is an inactive labeled fluorescent dye, which can be used to label proteins, antibodies, polysaccharides. The use of Vari Fluor carboxylic acid derivatives requires carboxylic acid activation.
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- HY-155323
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Fluorescent Dye
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Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-W103047
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Fluorescent Dye
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1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells .
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- HY-D2164
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Fluorescent Dye
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AF 430 alkyne is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via Alkyne groups and molecules containing Azide groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-D2768
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Fluorescent Dye
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BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
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- HY-D1366
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Fluorescent Dye
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Sulfo-Cyanine5.5 carboxylic acidCI Pigment violet 32 is a water-soluble, far-red emitting fluorophore. Due to its four sulfo groups, this dye has a negative charge at neutral pH and is very hydrophilic. As a cyanine dye, sulfo-Cyanine5.5 shows a very low dependence of fluorescence on pH and a very high extinction coefficient.
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- HY-D1445
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Fluorescent Dye
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|
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
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- HY-D1679
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Fluorescent Dye
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Phalloidin-f-HM-SiR is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2023
-
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Fluorescent Dye
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ATTO 665 streptavidin is a streptavidin derivative of ATTO 665, it can label protein or antibody, the maximum excitation/emission wavelength: 663/680 nm.
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- HY-D2475
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Fluorescent Dye
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2-Amino-5-methoxybenzamidoxime is a chemical probe for detection of ketone, including aromatic ketones, hydroxyl ketones, cyclic ketones and aliphatic ketones. 2-Amino-5-methoxybenzamidoxime exhibits an excitation maximal wavelength of 389 nm and a emission maximal wavelength of 515 nm .
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- HY-W019823
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Fluorescent Dye
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|
4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
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- HY-D2649
-
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Fluorescent Dye
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|
Cy5 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
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- HY-130916
-
|
5(6)-CarboxyrhodaMine 6G, succinimidyl ester
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Fluorescent Dye
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5(6)-CR6G,SE (5(6)-CarboxyrhodaMine 6G) is a trace fluorescent labeling reagent for fluorescence imaging of protein crystallization. 5(6)-CR6G,SE can efficiently bind to proteins to produce characteristic fluorescence under specific excitation conditions. 5(6)-CR6G,SE shows a peak absorption wavelength of approximately 525 nm and exhibits a peak fluorescence emission wavelength of around 550 nm when excited by a 530 nm green LED .
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- HY-D1336
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Fluorescent Dye
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FAM amine, 6-isomer is a fluorescein derivative with an amine group and contains an isomer of the fluorophore. Can be used to modify biomolecules through enzymatic transamination. Its fatty amine groups can also react with electrophiles such as activated esters. The amine can also be conjugated to carbonyl compounds (aldehydes and ketones) by reductive amination.
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- HY-D2751
-
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Fluorescent Dye
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BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
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- HY-D2643
-
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Fluorescent Dye
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|
Cy5 HA (MW 50000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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- HY-156303
-
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Fluorescent Dye
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|
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D1372
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Fluorescent Dye
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Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
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- HY-D2063
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Fluorescent Dye
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ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
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- HY-D2109
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Fluorescent Dye
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TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-D2687
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Fluorescent Dye
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|
Cy7 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-D2509
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Fluorescent Dye
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Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
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- HY-D2121A
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Fluorescent Dye
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Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D1414
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Fluorescent Dye
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Cyanine 3 Bisfunctional MTSEA Dye potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-137834
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Fluorescent Dye
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Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .
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- HY-D1620
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- HY-D2619
-
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Fluorescent Dye
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ICG PEG5000 FA is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG5000 FA is widely used in drug delivery and biomaterial labeling (Ex/Em=785/813 nm).
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- HY-D1306
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Fluorescent Dye
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TAMRA azide, 6-isomer is an isomer of TAMRA. TAMRA azide, 6-isomer is the linker of TAMRA.
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- HY-D1627
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CM-DiI
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Fluorescent Dye
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CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .
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- HY-140938A
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Fluorescent Dye
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(Rac)-Biotin-PEG3-oxyamine hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-123051
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Fluorescent Dye
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Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate .
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- HY-D2847A
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Fluorescent Dye
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FITC-PEG3400-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
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- HY-W269179
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Fluorescent Dye
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4-Bromomethyl-6,7-dimethoxycoumarin is a fluorescent label for carboxylic acids in chromatographic detection .
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- HY-D2611
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Fluorescent Dye
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ICG PEG3400 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG3400 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
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- HY-D2660
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Fluorescent Dye
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Cy5.5 HA (MW 50000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-138159
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Fluorescent Dye
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Boc-Lys(Ac)-AMC is a cell-permeable fluorometric HDAC substrate (Ex/Em = 355 nm/460 nm) .
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- HY-D1540
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Cy 5.5 amine; LumiProbe Cy 5.5 amine
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Fluorescent Dye
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Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
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- HY-D1605
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Fluorescent Dye
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BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm) .
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- HY-D1580
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Fluorescent Dye
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C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides .
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- HY-W324458
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Fluorescent Dye
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MCA succinimidyl ester is a derivative of MCA (HY-W027544). MCA succinimidyl ester has succinimidyl ester can react selectively with amines. MCA succinimidyl ester can be used as peptide substrate for fluorescence resonance energy transfer .
|
- HY-134566
-
|
|
Fluorescent Dye
|
|
NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates .
|
- HY-D2869
-
|
|
Fluorescent Dye
|
|
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .
|
- HY-101891
-
|
|
Fluorescent Dye
|
|
Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in Vm .
|
- HY-D2613
-
|
|
Fluorescent Dye
|
|
ICG PEG10000 DSPE is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG10000 DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=785/813 nm).
|
- HY-D0716
-
|
Fluo-3-pentaacetoxymethyl ester
|
Fluorescent Dye
|
|
Fluo-3 AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Fluo-3 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
- HY-133883
-
|
|
Fluorescent Dye
|
|
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .
|
- HY-D1524
-
|
1,8-EDNAS
|
Fluorescent Dye
|
|
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent .
|
- HY-D1496
-
|
|
Fluorescent Dye
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
- HY-D2856A
-
|
|
Fluorescent Dye
|
|
FITC-PEG2000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
|
- HY-D2053
-
|
|
Fluorescent Dye
|
|
ATTO 532 hydrazid is a hydrazide derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
- HY-150150F
-
|
|
Fluorescent Dye
|
|
Cy3-siRNA Negative Control is Cy3-labeled SiRNA Negative Control (HY-150150). Cy3-siRNA Negative Control can be used for easy visualization and assessment of transfection efficiency.
|
- HY-D2773
-
|
|
Fluorescent Dye
|
|
5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9).
Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
- HY-D2043
-
|
|
Fluorescent Dye
|
|
ATTO 620 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 620/642 nm.
|
- HY-W075603
-
|
2,6-Diiodo-Pyrromethene 546
|
Fluorescent Dye
|
|
2,6-Diiodo-BODIPY 493/503 is an F-Bodipy fluorescent dye with diiodo substitution at the (pyrrole) 2,6 position. 2,6-Diiodo-BODIPY 493/503 has a pyrrole iodine substituent that turns it red .
|
- HY-D2401F
-
|
|
Fluorescent Dye
|
|
Cy5-Polystyrene microsphere (100 nm) is a Cy5 (HY-D0821)-labeled microsphere that can be used for bioimaging and drug delivery .
|
- HY-D0853A
-
|
H-L-Photo-lysine hydrochloride
|
Fluorescent Dye
|
|
DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe .
|
- HY-D1777
-
|
PM605
|
Fluorescent Dye
|
|
Pyrromethene 605 (PM605) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
|
- HY-101897
-
|
Fura-2 Acetoxymethyl ester
|
Fluorescent Dye
|
|
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
|
- HY-D0219
-
|
Thymolsulphonephthalein
|
Fluorescent Dye
|
|
Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI - form) under acidic conditions and blue (I 2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
|
- HY-D1065
-
|
|
Fluorescent Dye
|
|
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
|
- HY-W190932
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
- HY-135638
-
- HY-D0070
-
|
Diaminofluorescein 2T
|
Fluorescent Dye
|
|
DAF-2T (Diaminofluorescein 2T) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-W442295
-
|
|
Fluorescent Dye
|
|
Dipyrrometheneboron difluoride is a green-fluorescent dye used for labeling nonpolar lipids and detecting calcium.
|
- HY-D3388
-
|
|
Fluorescent Dye
|
|
BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
|
- HY-D1708
-
- HY-DY1033
-
|
|
Fluorescent Dye
|
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) (solution) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di (β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
Solvent and concentration: DMSO: 10 mM
|
- HY-18743
-
|
|
Fluorescent Dye
|
|
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm) .
|
- HY-D2841
-
|
|
Fluorescent Dye
|
|
FITC-Heparin is a fluorescent dye composed of FITC (HY-66019) and Heparin. FITC-Heparin can be used for cell tracing and drug delivery .
|
- HY-D2225
-
- HY-D2730
-
|
|
Fluorescent Dye
|
|
N14G-Fe, the Fe 3+-chelated form of N14G, identifies Mtb in sputum samples with tuberculosis, exhibiting exceptional fluorescence. N14G-Fe can effectively traverse the cell wall and inner membrane region where IrtAB is located .
|
- HY-D2736
-
|
|
Fluorescent Dye
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
- HY-D2603
-
|
|
Fluorescent Dye
|
|
ICG PEG10000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG10000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
- HY-D1687
-
|
|
Fluorescent Dye
|
|
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells .
|
- HY-15941
-
|
Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
|
Fluorescent Dye
|
|
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
|
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dye
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
- HY-D2848A
-
|
|
Fluorescent Dye
|
|
Chitosan-Cy5.5 (MW 55000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 55000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm) .
|
- HY-157013
-
|
|
Fluorescent Dye
|
|
UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities .
|
- HY-D1482
-
|
|
Fluorescent Dye
|
|
Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
- HY-D2802D
-
|
|
Fluorescent Dye
|
|
FITC-PEG10000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2732
-
|
|
Fluorescent Dye
|
|
NFC nitro probe 1 (compound 18) is an NFC termed probe for Mtb detection. NFC nitro probe 1 (compound 18) shows high potency for R-Mtb and NR-Mtb .
|
- HY-DY1007
-
|
|
Fluorescent Dye
|
FITC (Fluorescein Isothiocyanate) (solution) , is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-W879370
-
- HY-D0165
-
|
1,3-Dihydroxynaphthalene
|
Fluorescent Dye
|
|
Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye (λex=330 nm, λem=380 nm) that can react with the NPPD (a tracer) and concentrated HCl and develop a red color. Naphthoresorcinol could be used as a background electrolyte (BGE) to determine the carbohydrates .
|
- HY-D2839
-
|
|
Fluorescent Dye
|
|
m-PEG10000-PEI-Cy5 is a fluorescent dye composed of polyethylene glycol (PEG), Cy5 (HY-D0821) and Polyethyleneimine (PEI). m-PEG10000-PEI-Cy5 can be used for fluorescent labeling and imaging .
|
- HY-W337201
-
|
|
Fluorescent Dye
|
|
5-Bromo-4-chloro-3-indolyl β-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases .
|
- HY-D2167
-
|
|
Fluorescent Dye
|
|
AF 568 alkyne is a derivative of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Alkyne group and molecules containing Azide groups. To achieve specific coupling of dye labels and biomolecules .
|
- HY-101900R
-
|
Nile blue sulfate (Standard)
|
Fluorescent Dye
|
|
Nile Blue A sulfate (Standard) is the analytical standard of Nile Blue A sulfate (HY-101900). This product is intended for research and analytical applications. Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor .
|
- HY-D2625
-
|
|
Fluorescent Dye
|
|
Cy3 HA (MW 50000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 50000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
- HY-D1356
-
|
|
Fluorescent Dye
|
|
Azide MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D0233
-
|
|
Fluorescent Dye
|
|
Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials .
|
- HY-D2123
-
|
|
Fluorescent Dye
|
|
Cy5-PEG3-SCO is a fluorescent dye that reacts with tetrazines and azides.
|
- HY-D1075
-
|
HIDC
|
Fluorescent Dye
|
|
1,1',3,3,3',3'-Hexamethylindodicarbocyanine iodide is a carbocyanine dye that stains mitochondria of live cells.
|
- HY-D1489
-
|
|
Fluorescent Dye
|
|
Ethyl eosin is a fluorescent dye with an absorption peak at 527 nm and an absorption shoulder at 487 nm .
|
- HY-118924
-
|
|
Fluorescent Dye
|
|
IR-825 is a near infrared fluorescent dye.the end of IR-825 has carboxyl COOH active group, and can participate in the reaction to connect other molecules. IR-825 can be widely used in tumor photothermal study. .
|
- HY-D0047
-
5-CFDA
3 Publications Verification
5-Carboxyfluorescein diacetate
|
Fluorescent Dye
|
|
5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
|
- HY-D1916
-
|
|
Fluorescent Dye
|
|
ATTO 594 is a Fluorescent dye (excitation/emission = 603/626 nm). ATTO 594 is covalently conjugated to Mucin via carbodiimide coupling .
|
- HY-D1352A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-D2840B
-
|
|
Fluorescent Dye
|
|
FITC-mPEG750 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG750 can be used for fluorescent labeling and imaging .
|
- HY-D1873
-
|
|
Fluorescent Dye
|
|
800CW acid is an orally active near-infrared (NIR) dye (excitation/emission 774/789 nm). 800CW acid can be used for intestinal permeability testing. 800CW acid can be used for in vivo imaging studies .
|
- HY-118262
-
|
|
Fluorescent Dye
|
|
Resorufin acetate is a fluorescent dye that selectively detects hydrazine .
|
- HY-D2249
-
- HY-D1352
-
|
|
Fluorescent Dye
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-W011618
-
|
|
Fluorescent Dye
|
|
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
|
- HY-P3484
-
|
|
Fluorescent Dye
|
|
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .
|
- HY-D2650
-
|
|
Fluorescent Dye
|
|
Cy5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
|
- HY-D0815
-
|
|
Fluorescent Dye
|
|
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
|
- HY-D1386
-
|
|
Fluorescent Dye
|
|
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .
|
- HY-D2360
-
|
|
Fluorescent Dye
|
|
O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity .
|
- HY-D2495
-
|
|
Fluorescent Dye
|
|
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.
|
- HY-D1557
-
|
|
Fluorescent Dye
|
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2748
-
|
|
Fluorescent Dye
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
- HY-D2180
-
|
|
Fluorescent Dye
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
- HY-D1304
-
|
|
Fluorescent Dye
|
|
Alexa fluor 488 azide ditriethylamine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-114958
-
|
|
Fluorescent Dye
|
|
RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase .
|
- HY-163140
-
|
|
Fluorescent Dye
|
|
BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction .
|
- HY-D1465
-
|
|
Fluorescent Dye
|
|
Alexa 532 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1426
-
|
|
Fluorescent Dye
|
|
Di-12-ANEPPQ is a fast-responding membrane potential dye. Di-12-ANEPPQ, the lipophilic dye, shows cell-specific loading and Golgi-like staining patterns with minimal background fluorescence in the slices of neocortex and hippocampus .
|
- HY-D2836J
-
|
FITC-Hyaluronate (MW 3000)
|
Fluorescent Dye
|
|
FITC-HA (MW 3000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
- HY-D2136
-
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Fluorescent Dye
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Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1594
-
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Fluorescent Dye
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BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .
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- HY-126821
-
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Fluorescent Dye
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Fluo-3 is a cell-impermeable calcium ion (Ca 2+) indicator. Fluo-3 itself is not fluorescent, but it becomes fluorescent after binding to calcium ions (Ex/Em = 488/525 nm) .
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- HY-D2077
-
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Fluorescent Dye
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ATTO 725 azide is an azide derivative of ATTO 725 with excitation/emission maxima at 728/751 nm. ATTO 725 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1924
-
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Fluorescent Dye
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ATTO 390 alkyne is an alkyne derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm. ATTO 390 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2711
-
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Fluorescent Dye
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Cy3 Dextran (MW 100000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm) .
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- HY-D2800D
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Fluorescent Dye
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FITC-PEG10000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG10000-MAL can be used for fluorescent labeling and imaging .
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- HY-D1949
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Fluorescent Dye
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ATTO 594 Streptavidin is a streptavidin derivative of ATTO 594, it can label protein or antibody, the maximum excitation/emission wavelength: 603/626 nm.
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- HY-D2856B
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Fluorescent Dye
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FITC-PEG3400-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-D2634
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Fluorescent Dye
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Cy3 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
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- HY-124409
-
WSP-1
2 Publications Verification
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Fluorescent Dye
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WSP-1 is a selective and rapid-reaction H2S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H2S with the releasing of fluorophore .
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- HY-D2421
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Fluorescent Dye
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DEAE-dex-Cy5 is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, Dextran (dex) and Diethylaminoethyl (DEAE). Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Dex has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander .
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- HY-D2606
-
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Fluorescent Dye
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ICG PEG3400 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG3400 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
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- HY-D2737
-
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BHQ-2 DMT amidite
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Fluorescent Dye
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DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
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- HY-D2855
-
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Fluorescent Dye
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Heparin-Cy7.5 is a fluorescent dye composed of CY7.5 (HY-D0926) and heparin. Heparin-CY7.5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 770/820 nm).
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- HY-D1537
-
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DBCO-Cy5.5; Cyanine5.5 DBCO
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Fluorescent Dye
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Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging .
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- HY-D2684
-
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Fluorescent Dye
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Cy7 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-131029
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JF646, Maleimide
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Fluorescent Dye
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Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
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- HY-D1578
-
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Fluorescent Dye
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C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .
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- HY-111391
-
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Diazoresorcinol sodium
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Fluorescent Dye
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Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
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- HY-D2605
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Fluorescent Dye
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ICG PEG2000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG2000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
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- HY-D2694
-
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Fluorescent Dye
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|
Cy7.5 HA (MW 100000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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- HY-DY1045
-
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Fluorescent Dye
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Methoxy-X04 (solution) is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity .
Solvent and concentration: DMSO: 5 mg/mL
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- HY-D0162R
-
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MCCK1 (Standard)
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Fluorescent Dye
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Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate (HY-D0162). This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
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- HY-101888
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Fluorescent Dye
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Cresyl Violet acetate is a dye, which can be used to stain neurons.
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- HY-D2268A
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Fluorescent Dye
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QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
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- HY-D2428
-
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Fluorescent Dye
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OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .
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- HY-158746
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Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity
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Fluorescent Dye
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Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration .
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- HY-172717
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Fluorescent Dye
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TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.
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- HY-131131
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Fluorescent Dye
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5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein, which contains an additional negative charge and can be better retained in the cell. 5-CFDA-AM can be used to detect cell viability .
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- HY-D1626
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3,3'-Dioctadecylthiacarbocyanine perchlorate
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Fluorescent Dye
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DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling .
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- HY-D0037
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Fluorescent Dye
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5-Bromomethyl-fluorescein is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2846B
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Fluorescent Dye
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m-PEG5000-PEI5000-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG5000-PEI5000-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em=633/670 nm).
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- HY-129887
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Fluorescent Dye
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Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .
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- HY-D3304
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Fluorescent Dye
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Cholyl-L-lysine fluorescein disodium is a Fluorescent substrate. Cholyl-L-lysine fluorescein disodium can be used in organoid research .
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- HY-136886
-
IR-820
2 Publications Verification
New Indocyanine Green
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Fluorescent Dye
|
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IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals .
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- HY-113217F
-
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Fluorescent Dye
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|
BODIPY 480/508-cholesteryl oleate is a fluorescently tagged derivative of Cholesteryl oleate (HY-113217). BODIPY 480/508-cholesteryl oleate can be used to monitor lipid transport mechanisms in mammalian cells (Ex/Em = 480/508 nm) .
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- HY-101893R
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Fluorescent Dye
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Dihydrofluorescein diacetate (Standard) is the analytical standard of Dihydrofluorescein diacetate (HY-101893). This product is intended for research and analytical applications. Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
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- HY-D2270
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Fluorescent Dye
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Halo tag TMR is a red fluorescent dye composed of Halo tag ligand molecules and TMR (TAMRA). Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity (Ex/Em = 550/576 nm) .
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- HY-116862
-
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DBF
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Fluorescent Dye
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Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its Km value of 0.87-1.9 μM (Ex=485 nm，Em=535 nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .
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- HY-D2431
-
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Fluorescent Dye
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Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .
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- HY-D2686
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Fluorescent Dye
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|
Cy7 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-DY1032
-
|
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Fluorescent Dye
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Mito-Tracker Green (solution) is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.
Solvent and concentration: DMSO: 1 mM
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- HY-D2657
-
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Fluorescent Dye
|
|
Cy5.5 HA (MW 5000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-D2682
-
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Fluorescent Dye
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Cy7 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-141575
-
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Fluorescent Dye
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C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
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- HY-W009756
-
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Fluorescent Dye
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|
N-Phenyl-1-naphthylamine is a dye that fluoresces strongly when bound to the inner phospholipid bilayer of Gram-negative bacteria. N-Phenyl-1-naphthylamine can be used to measure outer membrane permeability. N-Phenylnaphthalen-1-amine is a fluorescence probe for odorant-binding proteins (OBP) with a dissociation constant of 1.67 μM. N-Phenylnaphthalen-1-amine exhibits an excitation wavelength of 337 nM and an emission wavelength of 407 nM .
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- HY-W089353
-
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Fluorescent Dye
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8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .
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- HY-W190940
-
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Fluorescent Dye
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Biotin-PEG4-S-S-acid is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.
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- HY-D2543
-
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Fluorescent Dye
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Cy5-PEG3400-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D0103
-
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Fluorescent Dye
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Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
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- HY-D2231
-
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Fluorescent Dye
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Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
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- HY-D3449
-
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Fluorescent Dye
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8-(9-Bromoanthracene)-BODIPY 505/515 is a fluorescence turn-on probe with selective fluorescence turn-on response towards hydroxyl radical. 8-(9-Bromoanthracene)-BODIPY 505/515 can be used to detect reactive oxygen/nitrogen species (ROS/RNS) . (Ex/Em = 505/515 nm)
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- HY-D2420
-
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Fluorescent Dye
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Biotin-PEG5-Mal is a PROTAC linker, belonging to the PEG class. It can be used for the synthesis of PROTAC molecules .
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- HY-DY1101
-
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Fura-2 Acetoxymethyl ester (solution)
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Fluorescent Dye
|
Fura-2 AM (solution) (Fura-2 Acetoxymethyl ester (solution)) is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
Solvent and concentration: DMSO: 1 mM
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- HY-D2246
-
- HY-D2646
-
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Fluorescent Dye
|
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Cy5 HA (MW 200000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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- HY-D1517
-
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Fluorescent Dye
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FM 2-10 is a fluorescent dye. FM 2-10 is a less hydrophobic version of FM 1-43 (HY-D1434). FM 2-10 can be used for identifying actively firing neurons and investigating the mechanisms of activity-dependent vesicle cycling .
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- HY-D0076
-
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DAF-2
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Fluorescent Dye
|
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4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues .
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- HY-D2358
-
|
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Fluorescent Dye
|
|
Glucosamine-CY5.5 is CY5.5-labeled Glucosamine (HY-B1125). Glucosamine-CY5.5 can be used to localize Glucosamine in living cells .
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- HY-D2648
-
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Fluorescent Dye
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Cy5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY5 (HY-D0821). Cy5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 633/670 nm).
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- HY-D1415
-
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Fluorescent Dye
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Cyanine 5 Bisfunctional MTSEA Dye potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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- HY-151711
-
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Fluorescent Dye
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Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1896
-
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Fluorescent Dye
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Chloride Ionophore IV is a thiourea type hydrogen bonding-based receptor. Chloride Ionophore IV is a chloride ionophore .
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- HY-D1740
-
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DHTM Ros
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Fluorescent Dye
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Dihydrotetramethylrosamine (DHTM Ros) is a fluorogenic substrate for peroxidase that oxidizes to fluorescent tetramethylrosamine chloride.
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- HY-D2817
-
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Fluorescent Dye
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FITC-PLL is a fluorescent dye composed of poly-lysine (PLL) and FITC (HY-66019). FITC-PLL can be used for cell labeling and has nucleic acid binding ability .
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- HY-D1911
-
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Fluorescent Dye
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ATTO 665 Biotin is a biotin derivative of ATTO 665 with maximum excitation/emission wavelengths: 663/680 nm.
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- HY-D2844
-
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Fluorescent Dye
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FITC-PEG400-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG400-FA can be used for fluorescent labeling and imaging .
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- HY-D3256
-
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Fluorescent Dye
|
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AF 532 NHS ester is a fluorescent dye AF 532 derivative exhibits high fluorescence quantum yield and high photostability. AF 532 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 530/555 nm).
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- HY-D2802C
-
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Fluorescent Dye
|
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FITC-PEG5000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2836D
-
|
FITC-Hyaluronate (MW 50000)
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Fluorescent Dye
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FITC-HA (MW 50000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D2573
-
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Fluorescent Dye
|
|
Cy5.5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.
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- HY-D1872
-
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Fluorescent Dye
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800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
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- HY-D2836C
-
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FITC-Hyaluronate (MW 100000)
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Fluorescent Dye
|
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FITC-HA (MW 100000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D1705
-
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Fluorescent Dye
|
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Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .
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- HY-D1522
-
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Fluorescent Dye
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N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine is a fluorescent reagent .
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- HY-116583
-
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Fluorescent Dye
|
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Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .
|
- HY-D0074
-
|
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Fluorescent Dye
|
|
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent .
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- HY-D1678
-
|
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Fluorescent Dye
|
|
5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm) .
|
- HY-D1028
-
|
|
Fluorescent Dye
|
|
DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins (Ex/Em = 633/665 nm) .
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- HY-D1326
-
|
|
Fluorescent Dye
|
|
Cyanine3 carboxylic acid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-D1703
-
|
|
Fluorescent Dye
|
|
Oxazine 170 perchlorate is a laser dye with a wide excitation spectrum range (300−550 nm), which strongly absorbs light with a wavelength greater than 550 nm, and it emits fluorescence with a wavelength of about 645 nm .
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- HY-D1427
-
|
|
Fluorescent Dye
|
|
Di-2-ANEPEQ is a voltage sensitive membrane potential fluorescence dye. Di-2-ANEPEQ can be used for the evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system .
|
- HY-D1042
-
|
|
Fluorescent Dye
|
|
1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
|
- HY-D3308
-
|
|
Fluorescent Dye
|
|
CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion .
|
- HY-D1851
-
|
|
Fluorescent Dye
|
|
Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-W998694
-
|
|
Fluorescent Dye
|
|
6-CR, 6G is an acceptor chromophore commonly used in energy transfer (ET) fluorescent primers .
|
- HY-D1471
-
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|
Fluorescent Dye
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|
10-(3-Sulfopropyl)acridinium Betaine is a fluorescent dye with high durability (>3 months) .
|
- HY-P3749
-
|
|
Fluorescent Dye
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|
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .
|
- HY-D2226
-
- HY-W998707
-
|
|
Fluorescent Dye
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
- HY-101899
-
|
Chlorobimane，mBBr
|
Fluorescent Dye
|
|
Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
|
- HY-D2795C
-
|
|
Fluorescent Dye
|
|
FITC-PEG10000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG10000-COOH can be used for fluorescent labeling and imaging .
|
- HY-D2734
-
|
|
Fluorescent Dye
|
|
Heparin-Cy3 is a fluorescent dye composed of Cy3 (HY-D0822) and Heparin. Heparin-Cy3 can be used for cell tracing and drug delivery .
|
- HY-156304
-
|
|
Fluorescent Dye
|
|
Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D2840I
-
|
|
Fluorescent Dye
|
|
FITC-mPEG20000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG20000 can be used for fluorescent labeling and imaging .
|
- HY-101898
-
|
Indo-1 Acetoxymethyl ester
|
Fluorescent Dye
|
|
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.
MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
|
- HY-114352
-
|
|
Fluorescent Dye
|
|
BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λex=504 nm, λem=510 nm) .
|
- HY-113238F
-
|
FITC-Sulfolithocholic acid
|
Fluorescent Dye
|
|
FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases .
|
- HY-D1525
-
|
|
Fluorescent Dye
|
|
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin .
|
- HY-D2846A
-
|
|
Fluorescent Dye
|
|
m-PEG2000-PEI2000-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG2000-PEI2000-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em=633/670 nm).
|
- HY-D2836A
-
|
FITC-Hyaluronate (MW 500000)
|
Fluorescent Dye
|
|
FITC-HA (MW 500000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
|
- HY-D1313
-
|
|
Fluorescent Dye
|
|
PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-112624F1
-
|
|
Fluorescent Dye
|
|
CY5-Dextran (MW 4000) is a fluorescent dye CY5 (HY-D0821)-labeled Dextran (HY-112624). Dextran-CY5 (MW 4000) can be used to visualize the specific subcellular distribution of dextran at the nanoscale .
|
- HY-D1307
-
|
|
Fluorescent Dye
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
- HY-D0113
-
|
|
Fluorescent Dye
|
|
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .
|
- HY-131021
-
|
JF549, Azide
|
Fluorescent Dye
|
|
Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2555
-
|
|
Fluorescent Dye
|
|
Cy5.5-PEG10000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG10000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
|
- HY-D0075
-
|
|
Fluorescent Dye
|
|
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .
|
- HY-D2850
-
|
|
Fluorescent Dye
|
|
Heparin-Cy5.5 is a fluorescent dye composed of CY5.5 (HY-D0924) and heparin. Heparin-CY5.5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 680/710 nm).
|
- HY-D0134
-
|
|
Fluorescent Dye
|
|
NIR-797-isothiocyanate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2767
-
|
|
Fluorescent Dye
|
|
MB 660R NHS Ester is a fluroescent agent with a terminal NHS ester group.MB 660R NHS Ester is a far-red fluorescent dye that has a maximal absorption of 665 nm and emission at 690 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D2379A
-
|
|
Fluorescent Dye
|
|
closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent .
|
- HY-D2844D
-
|
|
Fluorescent Dye
|
|
FITC-PEG5000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG5000-FA can be used for fluorescent labeling and imaging .
|
- HY-D0089
-
|
|
Fluorescent Dye
|
|
O'-(carboxymethyl)fluoresceinamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2215
-
|
|
Fluorescent Dye
|
|
Mito-CCY is a mitochondria-targeted, NIR-absorbing cryptocyanine probe. Mito-CCY displays a high photothermal conversion efficiency, good biological compatibility in vitro, and photoinduced cytotoxicity in HeLa cells .
|
- HY-D2102
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG7-NH2 is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
|
- HY-D1237
-
|
|
Fluorescent Dye
|
|
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
|
- HY-100512
-
|
Pentacarboxybenzene
|
Fluorescent Dye
|
|
Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.
|
- HY-D2258
-
|
|
Fluorescent Dye
|
|
Bio-17-ATP is a substrate that can be used for AMPylation assays .
|
- HY-160065F
-
|
|
Fluorescent Dye
|
|
FAM-sgc8c aptamer sodium is a 5-FAM labeled sgc8c aptamer sodium (HY-160065). sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. Binding of FAM-sgc8c aptamer sodium to PTK-7 induces the assembly of nanotags on the cell surface, resulting in strong fluorescence and SERS signals .
|
- HY-DY1004
-
|
|
Fluorescent Dye
|
BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm.
Solvent and concentration: DMSO: 5 mM.
|
- HY-103373
-
|
|
Fluorescent Dye
|
|
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively) . PE154 can label β-amyloid plaques in histochemical analysis .
|
- HY-D0139
-
|
|
Fluorescent Dye
|
|
Octadecyl Rhodamine B (perchlorate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1972
-
|
|
Fluorescent Dye
|
|
ATTO 610 Carboxy is a carboxyl derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
|
- HY-D2336
-
|
|
Fluorescent Dye
|
|
PROTAC Aster-A degrader-1 (compound NGF3) is a degrader of the sterol transport protein Aster-A. PROTAC Aster-A degrader-1 can be used as a fluorescence probe. (Red: Aster-A inhibitor, black: linker, Blue: E3 ligase ligand) .
|
- HY-D2826
-
|
|
Fluorescent Dye
|
|
FITC-Chitosan (MW 100000) is a chitosan (Chitosan) (HY-B2144A) labeled with FITC (HY-66019). FITC-Chitosan (MW 100000) combines the biological and physicochemical properties of chitosan (such as biocompatibility, positive charge, and nanoparticle-forming ability) with the fluorescent visibility of FITC (Ex/Em = ~485/535 nm) .
|
- HY-W800775
-
|
|
Fluorescent Dye
|
|
BP Fluor 647 Alkyne is a bright green-fluorescent dye optimal for use with the 633, 650 nm Argon laser. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The dye is water soluble and pH-insensitive from pH 4 to pH 10. The dye has 4 sulfonate groups which make it highly water soluble and cause less aggregation in the aqueous solution. BP Fluor 647 Alkyne is used for protein and antibody labeling, or nucleic acid applications with high labeling density.
|
- HY-151750
-
|
|
Fluorescent Dye
|
|
Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.
|
- HY-D2662
-
|
|
Fluorescent Dye
|
|
Cy5.5 HA (MW 200000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
|
- HY-D1091
-
|
|
Fluorescent Dye
|
|
DiSBAC2(3) is an anionic membrane-potential-sensitive dye. DiSBAC2(3) is a plasma membrane potential indicator .
|
- HY-106594B
-
|
Pigment blue 27
|
Fluorescent Dye
|
|
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) .
|
- HY-155327
-
|
|
Fluorescent Dye
|
|
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-114289
-
6-HEX
1 Publications Verification
|
Fluorescent Dye
|
|
6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group .
|
- HY-D2493
-
|
Cy7 COOH
|
Fluorescent Dye
|
|
Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds .
|
- HY-155438
-
|
|
Fluorescent Dye
|
|
Mal-Cz is a maltose-derived fluorescence-on imaging probe for the detection of E. coli and Staphylococcus aureus . It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-137103
-
|
|
Fluorescent Dye
|
|
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .
|
- HY-136784A
-
|
|
Fluorescent Dye
|
|
Rhod-2 sodium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 sodium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
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- HY-D1893
-
|
|
Fluorescent Dye
|
|
HEX azide, 6-isomer, a derivate of fluorescent dye hexachlorofluorescein (HEX), can be used for labeling oligonucleotides .
|
- HY-D2381
-
|
|
Fluorescent Dye
|
|
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .
|
- HY-D2695
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA (MW 200000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
- HY-W800831
-
|
|
Fluorescent Dye
|
|
Tetra-sulfo-Cy7 DBCO is a bright and photostable near-IR probe. The Cy7 DBCO is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy7 DBCO is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.
|
- HY-D1045
-
|
DABCYL; Para-methyl red
|
Fluorescent Dye
|
|
Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
|
- HY-136894
-
|
|
Fluorescent Dye
|
|
Rhod-5N is a cell-impermeant calcium-binding fluorescent dye composed of a BAPTA chelating group and a rhodamine fluorophore. Rhod-5N is often added to MOPS buffer to complex and indicate cation content. The selectivity of Rhod-5N for Cd 2+ is higher than other interfering cations ((Na+, K+, Mg 2+, Ca 2+, Zn 2+) except Pb 2+), and the detection limit is 3.1 μg/L .
|
- HY-D1365
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3(Me)COOH is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .
|
- HY-D2075
-
|
|
Fluorescent Dye
|
|
ATTO 740 streptavidin is a streptavidin derivative of ATTO 740, it can label protein or antibody, the maximum excitation/emission wavelength: 743/763 nm.
|
- HY-155327A
-
|
|
Fluorescent Dye
|
|
Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-DY1002
-
|
|
Fluorescent Dye
|
H2DCFDA (DCFH-DA) (solution) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) .
Solvent and concentration: DMSO: 10 mM.
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-D2159
-
|
|
Fluorescent Dye
|
|
Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2380
-
|
|
Fluorescent Dye
|
|
H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC50=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (Kd=1.72 μM). H2S probe 1 can be used in cancer research .
|
- HY-W216621
-
|
|
Fluorescent Dye
|
|
Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization .
|
- HY-D2027
-
|
|
Fluorescent Dye
|
|
ATTO 550 amine is an amine derivative of ATTO 550, the maximum excitation/emission wavelength: 554/576 nm.
|
- HY-D0097
-
|
|
Fluorescent Dye
|
|
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label. 7-Fluorobenzofurazan-4-sulfonic acid ammonium can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH) .
|
- HY-D2137
-
|
|
Fluorescent Dye
|
|
Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-101887
-
|
|
Fluorescent Dye
|
|
Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator .
|
- HY-112624F4
-
- HY-103594
-
|
|
Fluorescent Dye
|
|
2-Aminoacridone is a widely used fluorophore (λexc=428 nm, λem=525 nm).
|
- HY-D1564
-
|
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Fluorescent Dye
|
|
Cy7.5 hydrazide is a fluorophore Cy7.5-labeled hydrazide fluorescent dye.
|
- HY-D2107
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
|
- HY-131027
-
|
JF646, Azide
|
Fluorescent Dye
|
|
Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D3390
-
|
|
Fluorescent Dye
|
|
sCy5DA is a is a fluorescent D-amino acid . sCy5DA incorporates into bacterial peptidoglycan layers and cross-links via transpeptidase action, replacing peptidoglycan stem peptide D-amino acids. sCy5DA labels live bacterial cell walls, nascent peptidoglycan biosynthesis sites, and diverse bacterial species including Gram-negative, Gram-positive, and mycobacteria (Ex/Em = 646/665 nm) .
|
- HY-D2574
-
|
|
Fluorescent Dye
|
|
Cy5.5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.
|
- HY-D2865
-
|
|
Fluorescent Dye
|
|
Celltrack Deep Red is a fluorescent dye with a fluorescence signal that can be maintained for at least 72 h and has good stability. Celltrack Deep Red can be used for cell tracing and multi-generation cell movement tracking. Within a cell population, Celltrack Deep Red is only transferred to daughter cells and not to neighboring cells (Ex/Em = 630/650 nm) .
|
- HY-D1931
-
|
|
Fluorescent Dye
|
|
ATTO 590 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 594/622 nm.
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- HY-D2854
-
|
|
Fluorescent Dye
|
|
FITC-PEG400-CL is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-D2514
-
|
|
Fluorescent Dye
|
|
Cy3-PEG1000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG1000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
- HY-W726893
-
- HY-D2524
-
|
|
Fluorescent Dye
|
|
Cy3-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy3 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy3 is approximately 562-570 nm.
|
- HY-D1076
-
|
|
Fluorescent Dye
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|
DiIC16(3) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .
|
- HY-D2430
-
|
|
Fluorescent Dye
|
|
Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, Chitosan and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi .
|
- HY-D2032
-
|
|
Fluorescent Dye
|
|
ATTO 514 amine is an amine derivative of ATTO 514, the maximum excitation/emission wavelength: 511/531 nm.
|
- HY-D1881A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7 carboxylic acid TEA (compound 6m) is a cyanine dye .
|
- HY-D0214
-
|
|
Fluorescent Dye
|
|
Acid Red 94 sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Acid Red 94 sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus (FLV) infection through photodynamic action. Additionally, Acid Red 94 sodium can inhibit Aβ aggregation through light irradiation. Acid Red 94 sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research .
|
- HY-120649
-
|
|
Fluorescent Dye
|
|
SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .
|
- HY-D0128
-
|
7-Methoxy-4-methylcoumarin
|
Fluorescent Dye
|
|
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml .
|
- HY-D2849
-
|
|
Fluorescent Dye
|
|
Heparin-Cy5 is a fluorescent dye composed of CY5 (HY-D0821) and heparin. Heparin-CY5 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 633/670 nm).
|
- HY-D1859
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1994
-
|
|
Fluorescent Dye
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D1772
-
|
|
Fluorescent Dye
|
|
Nile Blue A perchlorate is a laser dye used for pulsed and CW operations.
|
- HY-D2842E
-
|
|
Fluorescent Dye
|
|
FITC-PEG10000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG10000-biotin can be used for fluorescent labeling and imaging .
|
- HY-D2268
-
|
|
Fluorescent Dye
|
|
QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
|
- HY-D2595
-
|
|
Fluorescent Dye
|
|
Cy7.5-PEG5000-DSPE is a PEG phospholipid with CY7.5 (HY-D0926) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy7.5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em=770/820 nm).
|
- HY-D1961
-
|
|
Fluorescent Dye
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
- HY-D0081
-
|
|
Fluorescent Dye
|
|
4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2506
-
|
|
Fluorescent Dye
|
|
Cy3-PEG3400-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG3400-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
|
- HY-111382
-
|
DTZ
|
Fluorescent Dye
|
|
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios .
|
- HY-D2116
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D1742
-
|
|
Fluorescent Dye
|
|
DeepRed Nucleus Dye is a novel cell permeant and far red-fluorescing DNA probe. DeepRed Nucleus Dye excites at a wavelength of 647 nm, close to the Ex, and produces a fluorescence spectrum extending from 665 nm out to beyond 780 nm wavelengths. DeepRed Nucleus Dye fluorescence reflects cellular DNA content. DeepRed Nucleus Dye can be used in combination with FITC and RPE-labelled antibodies, without the need for fluorescence compensation .
|
- HY-DY1006
-
|
|
Fluorescent Dye
|
Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis.
Solvent and Concentration: Sterile water: 1 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
- HY-137834A
-
|
|
Fluorescent Dye
|
|
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)
|
- HY-D1477
-
|
|
Fluorescent Dye
|
|
5(6)-Carboxyfluorescein diisobutyrate is a protected 5(6)-carboxyfluorescein. 5(6)-carboxyfluorescein is a fluorescence pH indicator .
|
- HY-D2703
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA biotin (MW 5000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
|
- HY-42984
-
|
|
Fluorescent Dye
|
|
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D1669
-
|
|
Fluorescent Dye
|
|
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-114353
-
|
|
Fluorescent Dye
|
|
BODIPY FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments .
|
- HY-D1971
-
|
|
Fluorescent Dye
|
|
ATTO 725 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 728/751 nm.
|
- HY-101878
-
|
Sulforhodamine 101; SR101
|
Fluorescent Dye
|
|
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
|
- HY-D1603
-
|
|
Fluorescent Dye
|
|
BODIPY FL-EDA is a widely used fluorescent dye for quantitative analysis of nucleotides. BODIPY FL-EDA is an aliphatic amine analog that can react with aldehydes and ketones. BODIPY FL-EDA can be used to detect both modified and unmodified deoxynucleotides and to determine DNA damage and genomic DNA methylation through capillary electrophoresis with laser-induced fluorescence (CE-LIF). Additionally, it can be used for quantifying intracellular ATP levels. The excitation wavelength is 500 nm, and the emission wavelength is 510 nm .
|
- HY-123533A
-
|
NSC 12097 sodium salt
|
Fluorescent Dye
|
|
Resorufin sodium salt (NSC 12097) is a highly fluorescent pink dye. Resorufin sodium salt shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin sodium salt is used for the detection of ROS/RNS and a second analyte .
|
- HY-DY1077
-
|
|
Fluorescent Dye
|
Rhodamine B (solution) is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
Solvent and concentration: DMSO: 10 mM
|
- HY-D2840C
-
|
|
Fluorescent Dye
|
|
FITC-mPEG1000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG1000 can be used for fluorescent labeling and imaging .
|
- HY-D2114
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D2546
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2000-biotin is a polyethylene glycol derivative containing Cy5 (HY-D0821) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5-PEG2000-biotin plays an important role in the specific capture and detection of biomolecules.
|
- HY-W094758A
-
|
|
Fluorescent Dye
|
|
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λex /λem = 475/606 nm) .
|
- HY-D1327
-
|
|
Fluorescent Dye
|
|
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm) [1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2321
-
|
|
Fluorescent Dye
|
|
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form .
|
- HY-DY1098
-
|
2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)
|
Fluorescent Dye
|
BCECF (solution) (2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)) is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
Solvent and concentration: DMSO: 10 mM
|
- HY-111956
-
|
|
Fluorescent Dye
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
- HY-DY1080
-
|
Monodansyl cadaverine (solution)
|
Fluorescent Dye
|
Dansylcadaverine (solution) (Monodansyl cadaverine (solution)) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
Solvent and concentration: DMSO: 10 mM
|
- HY-D1431
-
|
|
Fluorescent Dye
|
|
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm .
|
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dye
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-101894R
-
|
DHR 123 (Standard)
|
Fluorescent Dye
|
|
Dihydrorhodamine 123 (Standard) is the analytical standard of Dihydrorhodamine 123 (HY-101894). This product is intended for research and analytical applications. Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
|
- HY-D0922
-
|
|
Fluorescent Dye
|
|
Cy3.5 is a fluorescent dye that can be used to label antibodies .
|
- HY-D1775
-
|
|
Fluorescent Dye
|
|
LysoTracker blue DND-22 is a blue fluorescent dye (Ex/Em: 373/422 nm). LysoTracker blue DND-22 stains acidic regions in living cells. LysoTracker blue DND-22 is used in the researches of neurodegenerative diseases and leukemia .
|
- HY-D1390
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5-Mal potassium is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal potassium specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal potassium can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
- HY-D1938
-
|
|
Fluorescent Dye
|
|
ATTO 465 Biotin is a biotin derivative of ATTO 465 with maximum excitation/emission wavelengths: 453/506 nm.
|
- HY-D1553
-
|
|
Fluorescent Dye
|
|
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used to quantify viscosity, critical micelle concentration, and critical micelle temperature .
|
- HY-D1960
-
|
|
Fluorescent Dye
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D2046
-
|
|
Fluorescent Dye
|
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
- HY-D2000
-
|
|
Fluorescent Dye
|
|
ATTO 488 is a hydrophilic rhodamine-based fluorescent dye with strong absorption and high fluorescence quantum yield. ATTO 488 is suitable for flow cytometry (FACS), fluorescence in situ hybridization (FISH) and most other labeling uses (Ex/Em: 500/520 nm) .
|
- HY-P1986
-
|
|
Fluorescent Dye
|
|
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
|
- HY-162075
-
|
|
Fluorescent Dye
|
|
RF16 is a fluorescent macromolecular material. RF16 precisely retains in cells to track IRE1-Halo protein with the HaloTag ligand .
|
- HY-100575
-
|
Acriflavinium chloride 3,6-Acridinediamine mix
|
Fluorescent Dye
|
|
Acriflavine (Acriflavinium chloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine is an antiseptic agent. Acriflavine is a potent HIF-1 inhibitor that prevents the dimerization of HIF-1α and HIF-1β subunits. Acriflavine inhibits the interaction between monocarboxylate transporter 4 (MCT4) and Basigin. Acriflavine is used in cancer research, such as breast cancer, brain tumor and chronic myeloid leukemia. Acriflavine is a potent papain-like protease (PLpro) inhibitor, which inhibits SARS-CoV-2 .
|
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dye
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).
|
- HY-124171
-
|
|
Fluorescent Dye
|
|
Zinquin ethyl ester is a cell-permeable and lipophilic fluorescent derivative of Zinquin (HY-D0982). Zinquin ethyl ester reacts with protein-bound Zn 2+ in cells and forms fluorescent ternary adducts. Zinquin ethyl ester undergoes hydrolysis by intracellular esterases impeding its efflux across the plasma membrane (Ex/Em = 370/470 nm) .
|
- HY-D1335
-
|
|
Fluorescent Dye
|
|
TAMRA amine, 5-isomer is an isomer of TAMRA, a xanthene dye with orange emission.
|
- HY-D2252
-
- HY-D2759
-
|
|
Fluorescent Dye
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
|
- HY-D2193
-
|
|
Fluorescent Dye
|
|
AgAuSe Oil phase (1000 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
- HY-D0825
-
|
Sulfo-Cyanine7
|
Fluorescent Dye
|
|
CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-W848699
-
|
|
Fluorescent Dye
|
|
FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
|
- HY-W098721
-
|
|
Fluorescent Dye
|
|
Z-Gly-Sar-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-D1092
-
|
|
Fluorescent Dye
|
|
DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye .
|
- HY-D2120A
-
|
|
Fluorescent Dye
|
|
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D1693
-
|
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Fluorescent Dye
|
|
FBBBE is used to detect the production of H2O2 by cells. FBBBE can be triggered by intracellular H2O2 and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm) .
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- HY-101879R
-
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Fluorescent Dye
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|
Acridine Orange hydrochloride (Standard) is the analytical standard of Acridine Orange hydrochloride (HY-101879). This product is intended for research and analytical applications. Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm) .
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- HY-D1086
-
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6-ROX, SE
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Fluorescent Dye
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|
6-Carboxy-X-rhodamine, succinimidyl ester (6-ROX, SE) is a fluorescent dye for oligonucleotide labeling and automated DNA sequencing .
|
- HY-D2292
-
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Fluorescent Dye
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|
BODIPY TMR acid is a fluorescent dye. BODIPY TMR acid is a high quantum yield fluorophore which can be coupled with Rebastinib .
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- HY-D1976
-
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Fluorescent Dye
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|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
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- HY-D1773
-
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Fluorescent Dye
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|
YOYO-3 is a trimethine cyanine homodimer dye. YOYO-3 intercalates into AF488-tagged dsDNA molecules at the single-molecule level. YOYO-3 has a greater affinity for DNA than do EB and other Cyanine dyes .
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- HY-D1388
-
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|
Fluorescent Dye
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|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D2765
-
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Fluorescent Dye
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
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- HY-W800680
-
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Fluorescent Dye
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|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
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- HY-D2183
-
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Fluorescent Dye
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|
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .
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- HY-DY1069
-
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|
Fluorescent Dye
|
Cy3 NHS ester (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
- HY-126172
-
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Fluorescent Dye
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|
9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives .
|
- HY-173308
-
|
|
Fluorescent Dye
|
|
QSY-21 is a fluorescence quencher. QSY-21 possesses broad absorption in far red and NIR range, and can quench fluorescence of dyes that emit in this region. This is a carboxylic acid derivative. QSY-21 has intense absorption maximum at 661 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications. It is a common quencher for Cyanine5, Cyanine5.5, AF 647, or other spectrally similar fluorescent dyes.
|
- HY-D2178
-
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|
Fluorescent Dye
|
|
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
|
- HY-DY1088
-
|
N-(5-Fluoresceinyl)maleimide (solution)
|
Fluorescent Dye
|
Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
Solvent and concentration: DMSO: 10 mM
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- HY-N2306R
-
|
Aclarubicin (Standard)
|
Fluorescent Dye
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Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
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- HY-D2621
-
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|
Fluorescent Dye
|
|
Cy3 HA (MW 5000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
|
- HY-D1691
-
|
|
Fluorescent Dye
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester can be used for the labeling of amine containing biomolecules .
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- HY-D2149
-
|
|
Fluorescent Dye
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|
Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D3387
-
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|
Fluorescent Dye
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|
TBI is a fluorescence enhancer with a Kd of 71 nM for the Broccoli fluorogenic RNA aptamer. TBI binds to the Broccoli fluorogenic RNA aptamer to activate its fluorescence.TBI undergoes photobleaching of its trans form, which dissociates rapidly, while cis-TBI from the media replaces the dissociated fluorophore to enable fluorophore recycling.TBI enables enhanced fluorescence of Broccoli during continuous cellular imaging (Ex/Em = 485/527 nm) .
|
- HY-D2162
-
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Fluorescent Dye
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|
AF 594 carboxylic acid is a carboxyl derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 carboxylic acid can form stable covalent bonds through the reaction of carboxylic acid groups with molecules with amino groups .
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- HY-D2858B
-
|
|
Fluorescent Dye
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|
8-arm-PEG40000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-arm-PEG40000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm) .
|
- HY-117070
-
|
|
Fluorescent Dye
|
|
TO-PRO-3 iodide is a cell-impermeant nucleic acid stain. TO-PRO-3 iodide is useful as a nuclear counterstain and dead cell indicator (Ex/Em = 642/661 nm).
|
- HY-138200
-
|
Cyanine5 maleimide
|
Fluorescent Dye
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|
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).
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- HY-D1541
-
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Fluorescent Dye
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|
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
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- HY-D2172
-
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|
Fluorescent Dye
|
|
AF488 carboxylic acid is a non-reactive AF 488 form. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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- HY-110251A
-
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|
Fluorescent Dye
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|
DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells .
|
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dye
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D2804
-
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Fluorescent Dye
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|
Chitosan-Cy7 (MW 10000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 10000) can be used for fluorescent labeling and imaging .
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- HY-D2401F1
-
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Fluorescent Dye
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|
Cy5-Polystyrene microsphere (20um) is a Cy5 (HY-D0821)-labeled microsphere that can be used for bioimaging and drug delivery .
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- HY-D1771
-
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Fluorescent Dye
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|
Thionin perchlorate is a general nuclear stain for chromatin and mucin.
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- HY-138659
-
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JF646, Tetrazine
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Fluorescent Dye
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Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D1573
-
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|
Fluorescent Dye
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|
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .
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- HY-D2843
-
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Fluorescent Dye
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|
FITC-PEG1000-FITC is a fluorescent dye composed of two FITC (HY-66019) molecules and one PEG. FITC-PEG-FITC is connected to each end of the two FITC (HY-66019) molecules to form a dual-labeling structure, which is suitable for high-sensitivity fluorescence detection and imaging (Ex/Em=488/525 nm) .
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- HY-D1978
-
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Fluorescent Dye
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|
ATTO 610 Biotin is a biotin derivative of ATTO 610 with maximum excitation/emission wavelengths: 616/633 nm.
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- HY-D0925
-
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Cyanine5.5 NHS ester
|
Fluorescent Dye
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|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
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- HY-135413
-
|
Sulfo-Cyanine5 NHS ester
|
Fluorescent Dye
|
|
MeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.
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- HY-D2666
-
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|
Fluorescent Dye
|
|
Cy5.5 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
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- HY-D2061
-
|
|
Fluorescent Dye
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|
ATTO 740 carboxy is a carboxyl derivative of ATTO 740, the maximum excitation/emission wavelength is: 743/763 nm.
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- HY-D0156
-
|
|
Fluorescent Dye
|
|
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry .
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- HY-D1421
-
|
|
Fluorescent Dye
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|
PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo .
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- HY-W013275
-
|
|
Fluorescent Dye
|
|
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
|
- HY-D2689
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA (MW 3000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
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- HY-D1514
-
- HY-D1680
-
|
|
Fluorescent Dye
|
|
LysoSR-549 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2445
-
|
|
Fluorescent Dye
|
|
AF405 acid is a fluorescent dye. AF405 exhibits a maximal excitation wavelength of 395 nm, and a maximal emission wavelength of 435 nm. AF405 is used for cell labeling and imaging .
|
- HY-D1373
-
HBC
3 Publications Verification
HBC 530
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Fluorescent Dye
|
|
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
|
- HY-138760
-
|
|
Fluorescent Dye
|
|
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells .
|
- HY-D0219A
-
|
|
Fluorescent Dye
|
|
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .
|
- HY-D1918
-
|
|
Fluorescent Dye
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
- HY-D2550
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
|
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dye
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
- HY-D2539
-
|
|
Fluorescent Dye
|
|
Cy3-PEG5000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2532
-
|
|
Fluorescent Dye
|
|
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-DY2001
-
|
|
Fluorescent Dye
|
Crystal Violet (solution) , also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining .
Solvent and Concentration: Sterile water: 5 mg/mL (0.5%)
|
- HY-D2600
-
|
|
Fluorescent Dye
|
|
ICG PEG2000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG2000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
- HY-D2190
-
- HY-D0971
-
|
Pyronine G; C.I. 45005
|
Fluorescent Dye
|
|
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .
|
- HY-D1566
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D0021
-
|
EtBr; Homidium bromide
|
Fluorescent Dye
|
|
EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
|
- HY-D2560
-
|
|
Fluorescent Dye
|
|
Cy5.5-PEG2000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2636
-
|
|
Fluorescent Dye
|
|
Cy3 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
|
- HY-D2794C
-
|
|
Fluorescent Dye
|
|
FITC-PEG10000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG10000-NH2 can be used for fluorescent labeling and imaging .
|
- HY-D2846
-
|
|
Fluorescent Dye
|
|
m-PEG-PEI800-Cy5 is a fluorescent dye composed of CY5 (HY-D0821), methoxypolyethylene glycol (mPEG), and polyethyleneimine (PEI). m-PEG-PEI8800-Cy5 is used for gene delivery, nanodrug delivery, cell imaging and biosensing and bioanalysis (Ex/Em = 633/670 nm).
|
- HY-D2197
-
|
|
Fluorescent Dye
|
|
AgAuSe-COOH (1120 nm) is a bright and biocompatible fluorescent nanoprobe in the second near-infrared window .
|
- HY-D1741
-
|
3,3'-Dihexadecyloxacarbocyanine
|
Fluorescent Dye
|
|
DiOC16(3) (3,3'-Dihexadecyloxacarbocyanine) is a lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and studies of membrane fluidity.
|
- HY-D2840H
-
|
|
Fluorescent Dye
|
|
FITC-mPEG10000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG10000 can be used for fluorescent labeling and imaging .
|
- HY-D3058
-
|
|
Fluorescent Dye
|
|
FITC-amide-C2 Lck inhibitor 2 is a FITC-labeled Lck inhibitor .
|
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dye
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D2590
-
|
|
Fluorescent Dye
|
|
Cy7.5 PEG-N3 is a CY7.5 (HY-D0926)-azide fluorescent dye used to label for protein and nucleic acid. Cy7.5 PEG-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 770/820 nm).
|
- HY-D1895A
-
|
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Fluorescent Dye
|
|
3,5-DiBr-PAESA sodium is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA sodium enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .
|
- HY-D1432
-
|
|
Fluorescent Dye
|
|
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor .
|
- HY-D2171
-
|
|
Fluorescent Dye
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
- HY-151713
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
|
- HY-D2110
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
- HY-D0079
-
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Hydroethidine; PD-MY 003
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Fluorescent Dye
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Dihydroethidium, also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
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- HY-D1982
-
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Fluorescent Dye
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
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- HY-121030
-
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N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
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Fluorescent Dye
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
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- HY-D2836I
-
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FITC-Hyaluronate (MW 5000)
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Fluorescent Dye
|
|
FITC-HA (MW 5000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D2544
-
|
|
Fluorescent Dye
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|
Cy5-PEG5000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D1402
-
|
|
Fluorescent Dye
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|
5MP-Fluorescein (compound 3e) is a fluorescein dye base on 5-Methylene pyrrolone (5MP).5-Methylene pyrrolones are highly thiol-specific and tracelessly removable bioconjugation tools .
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- HY-D1516
-
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Fluorescent Dye
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|
NerveGreen C3 is a cationic styrene based fluorescent dye. NerveGreen C3 can be used to track synaptic activity at neuromuscular junctions or synapses .
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- HY-D1964
-
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Fluorescent Dye
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ATTO 633 Biotin is a biotin derivative of ATTO 633 with maximum excitation/emission wavelengths: 630/651 nm.
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- HY-DY1092
-
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Ce6 (solution)
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Fluorescent Dye
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Chlorin e6 (solution) (Ce6 (solution)) is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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- HY-D2245
-
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Fluorescent Dye
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|
Cy5.5 phosphoramidite, a cyanine derivative, is a fluorescent labeling reagent for preparing fluorescence-labeled oligonucleotides .
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- HY-D2579
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Fluorescent Dye
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Sulfo DBCO-UBQ-2 is a click chemistry reagent combining a dark quencher, UBQ-2, with a polyaromatic-azo backbone, offering no native emission. UBQ-2 effectively quenches fluorescence in the 560-670 nm range, ideal for qPCR probes and FRET applications with orange to far-red dyes .
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- HY-D0011A
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Fluorescent Dye
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|
Bromophenol red (sultone form) is a chemical indicator. Bromophenol red (sultone form) binds to lysozyme and inhibits its activity against the bacterial cell wall, but not the polysaccharide component of peptidoglycan .
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- HY-W351340
-
|
|
Fluorescent Dye
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|
4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .
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- HY-D2148
-
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Fluorescent Dye
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AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules .
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- HY-W248118
-
|
PM556
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Fluorescent Dye
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Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
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- HY-D0934
-
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Fluorescent Dye
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(5)6-Carboxytetramethylrhodamine contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm .
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- HY-D1297
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Fluorescent Dye
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ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation .
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- HY-D1299
-
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CF3-substituted Tetramethyl BODIPY
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Fluorescent Dye
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meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy .
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- HY-D1098A
-
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Fluorescent Dye
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SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm .
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- HY-D2702
-
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Fluorescent Dye
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Cy7.5 HA biotin (MW 3000) is a biotinylated hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA biotin (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 770/820 nm).
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- HY-DY1081
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4',6-Diamidino-2-phenylindole dihydrochloride (solution)
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Fluorescent Dye
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DAPI (4',6-Diamidino-2-phenylindole) dihydrochloride (solution) is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm).
Solvent and concentration: ddH2O: 5 mg/mL
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- HY-D1349
-
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Fluorescent Dye
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Bodipy TR alkyneis one of a boron dipyrromethene fluorophore for the ROX (Texas Red) channel. This is a versatile fluorophore that can be used in microscopy, fluorescence polarization measurements, and other applications. This derivative is a terminal alkyne of copper-catalyzed click chemistry.
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- HY-D2844B
-
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Fluorescent Dye
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FITC-PEG2000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG2000-FA can be used for fluorescent labeling and imaging .
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- HY-D2348
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Fluorescent Dye
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ACE is a low-background, photostable fluorophore with nanomolar binding affinity for the Okra RNA aptamer. ACE enables clear visualization of mRNA in live bacteria and mammalian cells, including tracking the trafficking of mRNA to stress granules and dual-color super-resolution imaging of RNA in live cells. (Ex=488 nm, Em=555 nm) .
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- HY-D2824
-
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Fluorescent Dye
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Chitosan-Cy7.5 (MW 10000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 10000) can be used for fluorescent labeling and imaging .
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- HY-D2033
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Fluorescent Dye
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ATTO 514 azide is an azide derivative of ATTO 514 with excitation/emission maxima at 511/531 nm. ATTO 514 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2826B
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Fluorescent Dye
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FITC-Chitosan (MW 20000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 20000) can be used for fluorescent labeling and imaging .
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- HY-Y0016
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Basic Violet 10; Brilliant Pink B; Rhodamine O; Tetraethylrhodamine
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Fluorescent Dye
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Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
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- HY-P2208
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Fluorescent Dye
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Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
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- HY-D2641
-
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Fluorescent Dye
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Cy5 HA (MW 7000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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- HY-D1599
-
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R6GH
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Fluorescent Dye
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Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
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- HY-172666F
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Biotin ceramide (d18:0/6:0)
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Fluorescent Dye
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C6 Biotin dihydro ceramide is an affinity probe that allows C6 dihydro ceramide to be detected or immobilized through interaction with the biotin ligand.
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- HY-D2760A
-
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Fluorescent Dye
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BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
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- HY-D1367
-
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Fluorescent Dye
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Sulfo-Cyanine7 carboxylic acid is a highly hydrophilic and water-soluble near-infrared dye. It improves quantum yield in the near-infrared range and has a very high molar extinction coefficient.
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- HY-D2378
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- HY-D2853
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Fluorescent Dye
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FITC-PEG2000-PBA is a fluorescent dye composed of FITC (HY-66019), PEG and phenylboronic acid (PBA). FITC-PEG2000-PBA can be used for cell imaging and tracking, as well as sugar molecule detection (Ex/Em=488/525 nm).
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- HY-15922A
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Fluorescent Dye
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Luminol sodium salt is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol sodium salt exhibits chemiluminescence (CL) at 425 nm λmax. Luminol sodium salt is commonly used in forensics as a diagnostic tool for the detection of blood stains .
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- HY-D2659
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Fluorescent Dye
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|
Cy5.5 HA (MW 10000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-D2492
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Fluorescent Dye
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Sulfo Cy7 bis-COOH is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-D0212
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Fluorescent Dye
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Solvent blue 97 is a blue dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials.
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- HY-D2570
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Fluorescent Dye
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Cy5.5-PEG5000-Biotin is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and a Biotin. Biotin can bind with high affinity to streptavidin or avidin. Cy5.5-PEG5000-Biotin plays an important role in the specific capture and detection of biomolecules.
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- HY-D1919
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Fluorescent Dye
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ATTO 390 amine is a biotin derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm.
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- HY-D1301
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Fluorescent Dye
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BODIPY 581/591 C11 is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .
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- HY-101899R
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Chlorobimane，mBBr (Standard)
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Fluorescent Dye
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Monochlorobimane (Standard) is the analytical standard of Monochlorobimane (HY-101899). This product is intended for research and analytical applications. Monochlorobimane (Chlorobimane) is a fluorescent dye (λex=380 nm, λem=470 nm) to measure glutathione (GSH) in cellular assays .
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- HY-D2794
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Fluorescent Dye
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FITC-PEG400-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG400-NH2 can be used for fluorescent labeling and imaging .
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- HY-D1865
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Fluorescent Dye
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Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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- HY-175142
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Fluorescent Dye
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Prostaglandin E2-PEG11-biotin is a ligand. Prostaglandin E2-PEG11-biotin can be immobilized on flow cells. The immobilized Prostaglandin E2-PEG11-biotin binds to BtOCT1. Prostaglandin E2-PEG11-biotin can be used in SPR .
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- HY-D2388A
-
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Fluorescent Dye
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Sulfo Cy5.5-hydrazide sodium is a Cy5.5 (HY-D0924) dye derivative with hydrazine functionality. The hydrazide group of Sulfo Cy5.5-hydrazide sodium can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds .
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- HY-D2795A
-
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Fluorescent Dye
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FITC-PEG1000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG1000-COOH can be used for fluorescent labeling and imaging .
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- HY-D2910
-
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Fluorescent Dye
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Ox4 is a selective covalent modifier targeting Methionine residues. Ox4 is promising for research of protein functionalization, antibody-drug conjugate (ADC) synthesis, and proteome-wide identification of reactive methionine sites .
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- HY-D2318
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Fluorescent Dye
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Flipper-TR 5 is a Flipper probe containing a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 selectively labels the cytoplasmic membrane, and exhibits excellent mechanical sensitivity, negligible cytotoxicity and controllable phototoxicity .
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- HY-D2513
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|
Fluorescent Dye
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Cy3-PEG10000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG10000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D1555
-
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Cy7 DBCO
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Fluorescent Dye
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Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
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- HY-D2122
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Fluorescent Dye
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Cy3-PEG2-SCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-SCO carries a SCO group that can be covalently bound to an amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2160
-
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Fluorescent Dye
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AF 647 carboxylic acid is a derivative of the far-infrared dye AF 647. AF 647 is often used as a replacement for Cy5 dye, with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). The maximum excitation wavelength is 647 nm and the maximum emission wavelength is 671 nm. AF 647 carboxylic acid has a carboxylic acid group and can be coupled to biomolecules with amino groups to achieve dye labeling .
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- HY-D1884
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Fluorescent Dye
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6-FAM-DMT-PA is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- HY-D2564
-
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Fluorescent Dye
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Cy5.5-PEG1000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG1000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2568
-
|
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Fluorescent Dye
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Cy5.5-PEG10000-DSPE is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2637
-
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Fluorescent Dye
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|
Cy3 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
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- HY-D2554
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Fluorescent Dye
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Cy5.5-PEG5000-NH2 is a polyethylene glycol derivative containing Cy5.5 (HY-D0924) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy5.5 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy5.5 has an emission maximum around 710 nm. Cy5.5-PEG5000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling.
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- HY-D2422B
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Fluorescent Dye
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Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
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- HY-D2731
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Fluorescent Dye
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Cy3-NO2 is a cyanine-based probe. Cy3-NO2 can be excited by using a 554 nm laser and filtered with a 568 nm laser .
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- HY-D1725
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Fluorescent Dye
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Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .
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- HY-113823
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Fluorescent Dye
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Naphthol AS-G is an active compound. Naphthol ASG can be used for a series of synthetic organic pigments (SOP’s) research .
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- HY-D1535
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Fluorescent Dye
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IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
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- HY-D2065
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Fluorescent Dye
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ATTO 680 biotin is a biotin derivative of ATTO 680 with maximum excitation/emission wavelengths: 681/698 nm.
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- HY-D0456
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Fluorescent Dye
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C.I. Direct violet 66 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1613
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Fluorescent Dye
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BODIPY FL C5-HPC is a lipophilic green fluorescent dye (Ex/Em: 500/510 nm) .
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- HY-D2658
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Fluorescent Dye
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Cy5.5 HA (MW 7000) is a hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 680/710 nm).
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- HY-D2070
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Fluorescent Dye
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ATTO 680 cadaverin is a cadaverine derivative of ATTO 680, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 681/698 nm.
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- HY-D2624
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Fluorescent Dye
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Cy3 HA (MW 10000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
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- HY-131498
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Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
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Fluorescent Dye
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MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
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- HY-151701A
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Fluorescent Dye
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DiSulfo-Cy5 alkyne TEA is a fluorescent dye can be used as a click chemistry reagent .
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- HY-118562
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Fluorescent Dye
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Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group (Ex/Em: 360 nm/465 nm) .
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- HY-145499
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Fluorescent Dye
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XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.
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- HY-W277900
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Fluorescent Dye
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2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography .
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- HY-137100
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Cyanine5 hydrazide
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Fluorescent Dye
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Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .
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- HY-D2440
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Fluorescent Dye
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cRGD-PEG-Cy3 is a Cy3 (HY-D0822) labeled cRGD-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. cRGD can be used to modify lipid for improved stability .
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- HY-D2664
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Fluorescent Dye
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Cy5.5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
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- HY-D2156
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Fluorescent Dye
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AF 430 azide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 azide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the azide group and molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D2357
-
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Fluorescent Dye
|
|
Lactat-CY5 is Cy5-labeled Lactat (HY-B2227). Lactat-CY5 can be used to localize Lactat in living cells .
|
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
Fluorescent Dye
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
|
- HY-D1372A
-
|
|
Fluorescent Dye
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
- HY-D1500
-
|
|
Fluorescent Dye
|
|
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35) .
|
- HY-D1928
-
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|
Fluorescent Dye
|
|
ATTO 425 Amine is an amine derivative of ATTO 425, the maximum excitation emission wavelength: 439/489 nm.
|
- HY-D2602
-
|
|
Fluorescent Dye
|
|
ICG PEG5000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG5000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
|
- HY-D1904
-
|
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Fluorescent Dye
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|
D-Luciferin 6'-methyl ether sodium salt is a firefly luciferase inhibitor. D-Luciferin 6'-methyl ether sodium salt is a cofactor in Luc-catalyzed synthesis of dinucleoside polyphosphates .
|
- HY-D2874
-
|
|
Fluorescent Dye
|
|
6-AF488 tyramide is a bright, green fluorescent dye (Ex=496 nm, Em=524 nm). 6-AF488 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .
|
- HY-D2243
-
|
|
Fluorescent Dye
|
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
- HY-D0110B
-
|
|
Fluorescent Dye
|
|
Fura-2 pentasodium is a cell-impermeable scaled fluorescent dye that can be used for intracellular calcium imaging. Fura-2 pentasodium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca 2+ level .
|
- HY-D1869
-
|
|
Fluorescent Dye
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
- HY-137023
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7 amine is a cyanine containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.
|
- HY-D0104
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dye
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D2797
-
|
|
Fluorescent Dye
|
|
Chitosan-Cy7 (MW 2000) is a Chitosan labeled with Cy7 (HY-D0825). Chitosan-Cy7 (MW 2000) can be used for fluorescent labeling and imaging .
|
- HY-D1776
-
|
|
Fluorescent Dye
|
|
FFP-18-AM is a cell-permeable fluorescent indicator for measurement of near-membrane calcium.
|
- HY-D0395
-
|
|
Fluorescent Dye
|
|
C.I. Mordant Orange 29 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2801C
-
|
|
Fluorescent Dye
|
|
FITC-PEG5000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG5000-NHS can be used for fluorescent labeling and imaging .
|
- HY-D1977
-
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|
Fluorescent Dye
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|
ATTO 610 Streptavidin is a streptavidin derivative of ATTO 610, it can label protein or antibody, the maximum excitation/emission wavelength: 616/633 nm.
|
- HY-D1672
-
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Fluorescent Dye
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|
TMR Biocytin is a polar tracer used in the research of cell-cell and cell-liposome fusions, as well as membrane permeability and cellular uptake during pinocytosis. TMR Biocytin can be detected using streptavidin, and is an effective neuronal tracer in live tissue (Ex=544 nm, Em=571 nm) .
|
- HY-D1720
-
|
|
Fluorescent Dye
|
|
Cy5-dATP is a Cy5?(HY-D0821)-labeled dATP?(HY-136648). Cy5-dATP can be incorporated into a DNA primer .
|
- HY-D2052
-
|
|
Fluorescent Dye
|
|
ATTO 532 iodacetamid is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 iodacetamid is an iodoacetamide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
- HY-D1584
-
|
|
Fluorescent Dye
|
|
C12 NBD sphingomyelin is an active derivative of Sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .
|
- HY-D2668
-
|
|
Fluorescent Dye
|
|
Cy5.5 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
|
- HY-D2551
-
|
|
Fluorescent Dye
|
|
Cy5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
|
- HY-D1624
-
|
|
Fluorescent Dye
|
|
3,3′-Diheptylthiacarbocyanine iodide is a cyanine dye for measuring membrane potential. (λex=562 nm，λem=575 nm) .
|
- HY-109116
-
|
Leukomethylene blue
|
Fluorescent Dye
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|
Hydromethylthionine (Leukomethylene blue) has a very active photochemically active reagent, especially in its interaction with dissolved oxygen. The photochemical activity of Hydromethylthionine is mainly regulated by the reaction of its triplet state with dissolved oxygen, which reacts with dissolved oxygen to form Methylene Blue (HY-14536) and hydronium ions under ultraviolet light. Hydromethylthionine can be used for the photodegradation of model pollutants in semiconductor photocatalysis and for the study of indicators in chemical analysis .
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- HY-D1110
-
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|
Fluorescent Dye
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|
TFAX 594,SE is a red fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 594,SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
- HY-122878
-
|
|
Fluorescent Dye
|
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers .
|
- HY-D0060
-
|
|
Fluorescent Dye
|
|
4-Di-2-ASP, a styryl pyridinium fluorescent dye, is a vital mitochondrial marker. 4-Di-2-ASP shows reliable and specific labelling of pulmonary NEBs (neuroepithelial bodies) .
|
- HY-D1498
-
|
|
Fluorescent Dye
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|
Mag-Fluo-4 AM is a fluorecent Ca 2+ chelator, with high affinity for calcium. Mag-Fluo-4 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
|
- HY-DY1083
-
|
|
Fluorescent Dye
|
Zinquin (solution) is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
Solvent and concentration: DMSO: 5 mM
|
- HY-D1974
-
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|
Fluorescent Dye
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|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
|
- HY-N6716
-
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Fluorescent Dye
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|
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
|
- HY-D2422C
-
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|
Fluorescent Dye
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|
Cy5-Paclitaxel bromide is the bromide of Cy5-Paclitaxel (HY-D2422B). Cy5-Paclitaxel is a Cyanine5 carboxylic acid bromide (HY-D1319) labeled Paclitaxel (HY-B0015) conjugate. Cyanine5 carboxylic acid bromide is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
|
- HY-D1569
-
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|
Fluorescent Dye
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|
CellTracker Orange CMRA Dye is a fluorescent dye. CellTracker Orange CMRA Dye can be used for cell imaging and monitoring the movement and location of cells .
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- HY-135415A
-
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|
Fluorescent Dye
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|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
- HY-15922
-
Luminol
2 Publications Verification
Diogenes reagent
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Fluorescent Dye
|
|
Luminol is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λmax. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains .
|
- HY-D0142
-
|
|
Fluorescent Dye
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|
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO2 release .
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- HY-P3475
-
|
|
Fluorescent Dye
|
|
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
|
- HY-D1340
-
|
|
Fluorescent Dye
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
- HY-D1375A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .
|
- HY-D2049
-
|
|
Fluorescent Dye
|
|
ATTO 532 biotin is a biotin derivative of ATTO 532 with maximum excitation/emission wavelengths: 532/552 nm.
|
- HY-D2631
-
|
|
Fluorescent Dye
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|
Cy3 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY3 (HY-D0822). Cy3 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 550/570 nm).
|
- HY-D0147
-
|
Pentoxyresorufin
|
Fluorescent Dye
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|
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae .
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- HY-P1004A
-
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|
Fluorescent Dye
|
|
Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B) .
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- HY-D2009
-
|
|
Fluorescent Dye
|
|
ATTO 565 iodacetamid is an iodoacetamide derivative of ATTO 565 with maximum excitation/emission wavelengths: 564/590 nm.
|
- HY-D1111
-
|
AFDye 568 NHS Ester
|
Fluorescent Dye
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
- HY-D2747
-
|
|
Fluorescent Dye
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
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- HY-D2001
-
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|
Fluorescent Dye
|
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
- HY-D1074
-
|
3,3'-Dipropyloxacarbocyanine iodide
|
Fluorescent Dye
|
|
DiOC3(3) (3,3'-Dipropyloxacarbocyanine iodide) is a green fluorescent lipophilic dye with cell membrane permeability. DiOC3(3) can be used to stain cell membranes and other lipid-soluble biological structures .
|
- HY-D2743
-
|
|
Fluorescent Dye
|
|
ROX alkyne, 6-isomer is an alkyne derivative of the bright red-emitting dye ROX (Rhodamine X, Rhodamine 101). Due to its quantum yield approaching unity, ROX is a popular dye for qPCR and microscopy applications. It is used for fluorescent labeling of azide-containing biomolecules via copper-catalyzed click reaction.
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- HY-D2113
-
|
|
Fluorescent Dye
|
|
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D2847
-
|
|
Fluorescent Dye
|
|
FITC-PEG2000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
|
- HY-D1462
-
|
|
Fluorescent Dye
|
|
CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
|
- HY-D0925B
-
|
Cyanine5.5 NHS ester TEA
|
Fluorescent Dye
|
|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
- HY-Y0016R
-
|
Basic Violet 10 (Standard); Brilliant Pink B (Standard); Rhodamine O (Standard); Tetraethylrhodamine (Standard)
|
Fluorescent Dye
|
|
Rhodamine B (Standard) is the analytical standard of Rhodamine B. This product is intended for research and analytical applications. Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
|
- HY-W588722
-
|
|
Fluorescent Dye
|
|
ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
|
- HY-D2690
-
|
|
Fluorescent Dye
|
|
Cy7.5 HA (MW 5000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
- HY-D2638
-
|
|
Fluorescent Dye
|
|
Cy5 HA (MW 3000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
|
- HY-P2065
-
|
|
Fluorescent Dye
|
|
Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
|
- HY-D0084
-
|
DiOC6(3) iodide
|
Fluorescent Dye
|
|
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine dye which can be used to monitor changes in mitochondrial membrane potential.
|
- HY-D2325
-
|
|
Fluorescent Dye
|
|
Arg-Flipper 34 is one of the flipper probes which have been introduced as small molecule fluorophores to image membrane tension in living systems. Arg-Flipper 34 can be used to assess the mechanics of early endocytosis .
|
- HY-D2837
-
|
|
Fluorescent Dye
|
|
mPEG-PEI-Cy5 (MW 2000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). mPEG-PEI-Cy5 (MW 2000) can be used for fluorescent labeling and imaging .
|
- HY-D2842B
-
|
|
Fluorescent Dye
|
|
FITC-PEG2000-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG2000-biotin can be used for fluorescent labeling and imaging .
|
- HY-D1069
-
|
DBCO-Sulfo-Cy3
|
Fluorescent Dye
|
|
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D1738
-
|
4',6-Diamidino-2-phenylindole dilactate
|
Fluorescent Dye
|
|
DAPI (4',6-Diamidino-2-phenylindole) dilactate is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. DAPI cannot penetrate intact cell membranes and is commonly used for staining both live and fixed cells . DAPI (Compound 3) is an acid-sensing ion channel 3 (ASIC3) inhibitor. DAPI binds to ASIC3 and blocks the channel function. DAPI can be used in the study of chronic pain treatment (Ex/Em = 356/451 nm) .
|
- HY-D2500
-
|
|
Fluorescent Dye
|
|
CY7 DBCO chloride is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. CY7 DBCO chloride is a click chemistry reagent. CY7 DBCO chloride contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-D2153
-
|
|
Fluorescent Dye
|
|
Cy5-PEG2-SCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
- HY-D2124
-
|
|
Fluorescent Dye
|
|
Cy3-PEG7-SCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-SCO has a SCO group that can be covalently bonded to the amino group. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
|
- HY-D2013
-
|
|
Fluorescent Dye
|
|
ATTO 488 hydrazid is a hydrazide derivative of ATTO 488 with excitation/emission maxima at 500/520 nm.
|
- HY-D1848A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
- HY-D1560
-
|
|
Fluorescent Dye
|
|
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .
|
- HY-136784
-
|
|
Fluorescent Dye
|
|
Rhod-2 potassium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 potassium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
|
- HY-D0972
-
|
Thioflavin S; Direct Yellow 7
|
Fluorescent Dye
|
|
Thioflavine S is a fluorescent histochemical marker of dense core senile plaques. Thioflavine S can be used for Alzheimer's research .
|
- HY-D0025
-
|
|
Fluorescent Dye
|
|
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
|
- HY-D1942
-
|
|
Fluorescent Dye
|
|
ATTO 590 Biotin is a biotin derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
|
- HY-D1512
-
- HY-P2536
-
|
|
Fluorescent Dye
|
|
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .
|
- HY-W800808
-
|
|
Fluorescent Dye
|
|
ROX azide, 5-isomer is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
- HY-66019
-
|
Fluorescein 5-isothiocyanate
|
Fluorescent Dye
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FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
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- HY-D1696
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Fluorescent Dye
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MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm) .
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- HY-D2676
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Fluorescent Dye
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Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D0924A
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Sulfo-Cyanine5.5 acetate
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Fluorescent Dye
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Cy5.5 acetate is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-114907
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Eosinic acid; Solvent Red 72
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Fluorescent Dye
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4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis .
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- HY-D1945
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Fluorescent Dye
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ATTO 590 Iodacetamid is an iodoacetamide derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
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- HY-141085
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Fluorescent Dye
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Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D2844A
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Fluorescent Dye
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FITC-PEG1000-FA is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG1000-FA can be used for fluorescent labeling and imaging .
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- HY-D1359
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Fluorescent Dye
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Mito Red is a vital dye and mitochondrial stain that can be used to detect and evaluate mitochondrial function and status. Mito Red accumulates in mitochondria, and its fluorescence intensity is positively correlated with mitochondrial membrane potential. When the mitochondrial membrane potential increases, the fluorescence signal of Mito Red increases .
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- HY-D1648
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Fluorescent Dye
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8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λabs=502 nm, λem=516 nm) (*abs: main absorption maxima) .
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- HY-115692
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Fluorescent Dye
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2-Coumaranone-1-L serves as a chemiluminescent probe. Under alkaline conditions and in the presence of oxygen, 2-Coumaranone-1-L is capable of undergoing chemiluminescence, which enables its application as a chemiluminescent substrate in biochemical assays. 2-Coumaranone-1-L exhibits its maximum emission wavelength at 442 nm. 2-Coumaranone-1-L is utilized in research within the realm of bioanalysis .
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- HY-DY1095
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Fluo-3-pentaacetoxymethyl ester (solution)
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Fluorescent Dye
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Fluo-3AM (solution) is a fluorecent Ca 2+ chelator, with high affinity for calcium. Fluo-3 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .
Solvent and concentration: DMSO: 5 mM
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- HY-120317
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Fluorescent Dye
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CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .
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- HY-P3236
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Ac-IEPD-pNA
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Fluorescent Dye
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|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
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- HY-D2448
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Fluorescent Dye
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Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
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- HY-D2042
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Fluorescent Dye
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ATTO 610 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 616/633 nm.
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- HY-D1935
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Fluorescent Dye
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ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
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- HY-136248
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Tyramide-Cy3
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Fluorescent Dye
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Cyanine 3 Tyramide (Tyramide-Cy3) is an orange fluorescent dye used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, which serves as a signal amplification technique in immunoassays and in situ nucleic acid hybridization .
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- HY-D2239
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Fluorescent Dye
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Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
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- HY-D0130
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Fluorescent Dye
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Xanthamide 8 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D2072
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Fluorescent Dye
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ATTO 680 carboxy is a carboxyl derivative of ATTO 680, the maximum excitation/emission wavelength is: 681/698 nm.
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- HY-D0817
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Rhodamine 110 chloride; RH110
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Fluorescent Dye
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Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm .
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- HY-D1073
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3,3'-Diheptyloxacarbocyanine iodide
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Fluorescent Dye
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DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities .
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- HY-D2836H
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FITC-Hyaluronate (MW 7000)
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Fluorescent Dye
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FITC-HA (MW 7000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-D1946
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Fluorescent Dye
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ATTO 590 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 alkyne is an alkyne derivative of ATTO 590 and can be used to label proteins or antibodies.
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- HY-W271064
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Fluorescent Dye
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1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
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- HY-147170
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Fluorescent Dye
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(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes .
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- HY-D2836
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FITC-Hyaluronate (MW 1000000)
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Fluorescent Dye
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FITC-HA (MW 1000000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM) .
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- HY-101937
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Fluorescent Dye
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L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa) .
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- HY-D1429
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Fluorescent Dye
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ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K + channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence (Ex/Em = 374/ 430-640 nm) .
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- HY-D1944
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Fluorescent Dye
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ATTO 590 Azide is an azide derivative of ATTO 590 with excitation/emission maxima at 594/622 nm. ATTO 590 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1190
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Fluorescent Dye
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DC271 is a RAR agonist and synthetic retinoid that binds to the retinoid-binding site of cellular retinoic acid-binding protein II (CRBP-II). DC271 exhibits solvatochromic fluorescence properties: it produces intense blue-shifted emission in nonpolar environments and weak red-shifted emission in polar environments, and its severe fluorescence quenching in aqueous solutions can be reversed by embedding in the hydrophobic retinoid-binding protein pocket. DC271 enables direct detection of the binding between unlabeled compounds and related retinoid-binding proteins via fluorescence competition assays (Ex/Em = 355 nm/460 nm) .
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- HY-D2008
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Fluorescent Dye
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ATTO 488 amine is an amine derivative of ATTO 488, the maximum excitation/emission wavelength: 500/520 nm.
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- HY-D2798A
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Fluorescent Dye
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FITC-PEG1000-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG1000-SH can be used for fluorescent labeling and imaging .
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- HY-D2143
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Fluorescent Dye
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Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D2798
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Fluorescent Dye
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FITC-PEG400-SH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a sulfhydryl (SH). FITC-PEG400-SH can be used for fluorescent labeling and imaging .
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- HY-D1387
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Fluorescent Dye
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Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose .
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- HY-132264
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Fluorescent Dye
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FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .
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- HY-D1440
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Fluorescent Dye
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Rhodamine B, tetramethyl-, isothiocyanate (Tetramethylrhodamine B isothiocyante) is a fluorescent dye. Rhodamine B, tetramethyl-, isothiocyanate has a strong two-photon absorption at about 830 nm .
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- HY-D2696
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|
Fluorescent Dye
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|
Cy7.5 HA (MW 500000) is a hyaluronic acid labeled with CY7.5 (HY-D0926). Cy7.5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 770/820 nm).
|
- HY-D2222
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Fluorescent Dye
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5-HMSiR-Hoechst is a DNA probe. 5-HMSiR-Hoechst comprises Hoechst 33258 and spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). 5-HMSiR-Hoechst can stain living cells. Ex/Em=640 nm/675 nm .
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- HY-D1702
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Fluorescent Dye
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Mag-Fura-2 tetrapotassium is a cell-impermeant UV excitable rational fluorescent Mg 2+/Ca 2+ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg 2+ and Ca 2+ concentrations .
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- HY-D2512
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Fluorescent Dye
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Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
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- HY-W324406
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Fluorescent Dye
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1,2-Diamino-3,4-ethylenedioxybenzene is a carbonyl-reactive fluorometric labeling agent.
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- HY-D0813
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Fluorescent Dye
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Zincon sodium is an excellent colorimetric reagent for the detection of zinc and copper ions in aqueous solution. Zincon sodium can be used for the determination of zinc, copper, and cobalt ions in metalloproteins .
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- HY-172398
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Fluorescent Dye
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FAM phosphoramidite, 5-isomer is a standard fluorescein (FAM) phosphoramidite for 5'-terminal oligonucleotide labeling, high isomeric purity single isomer.
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- HY-D2518
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Fluorescent Dye
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Cy3-PEG10000-DSPE is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG10000-DSPE has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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- HY-D2545
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Fluorescent Dye
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Cy5-PEG10000-DSPE is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG10000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
- HY-101894
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DHR 123
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Fluorescent Dye
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Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
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- HY-D2842C
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Fluorescent Dye
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FITC-PEG3400-biotin is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Biotin (HY-B0511). FITC-PEG3400-biotin can be used for fluorescent labeling and imaging .
|
- HY-D1161
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NCI 240899
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Fluorescent Dye
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True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival .
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- HY-D2535
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Fluorescent Dye
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Cy5-PEG5000-N3 is a Cy5 (HY-D0821)-azide fluorescent dye used to label for protein and nucleic acid. Cy5-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2802
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Fluorescent Dye
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FITC-PEG400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D1686
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Biotin-16-UTP tetralithium
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Fluorescent Dye
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|
Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .
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- HY-D2120
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Fluorescent Dye
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Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- HY-D2640
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Fluorescent Dye
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|
Cy5 HA (MW 5000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
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- HY-D1930
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Fluorescent Dye
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ATTO 425 Azide is an azide derivative of ATTO 425, the maximum excitation and emission wavelength: 439/489 nm. ATTO 425 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D0853
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DiAzKs
1 Publications Verification
H-L-Photo-lysine
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Fluorescent Dye
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DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe .
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- HY-D1355
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Fluorescent Dye
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Azide cyanine dye 728 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D1252
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Fluorescent Dye
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Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
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- HY-D2795B
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Fluorescent Dye
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FITC-PEG5000-COOH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG5000-COOH can be used for fluorescent labeling and imaging .
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- HY-151774
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Fluorescent Dye
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TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .
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- HY-D0071
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Fluorescent Dye
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N-4-(5,6-Dimethoxy-N-phthalimidinyl)phenylmaleimide is a fluorescence reagent for labeling thiol .
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- HY-D2673
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Fluorescent Dye
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|
Cy7 HA (MW 55000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-156306
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Fluorescent Dye
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Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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- HY-D2739
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Fluorescent Dye
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SIMA phosphoramidite, 6-isomer is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA has higher stability during deprotection under alkaline conditions.
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- HY-D2620
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Fluorescent Dye
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CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models .
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- HY-D1633A
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Fluorescent Dye
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4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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- HY-D1530
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Fluorescent Dye
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4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide is a fluorogenic substrate for detecting α-N-acetylglucosaminidase .
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- HY-D1988
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Fluorescent Dye
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ATTO 620 Biotin is a biotin derivative of ATTO 620 with maximum excitation/emission wavelengths: 620/642 nm.
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- HY-104056
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Fluorescent Dye
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Fura Red is a Ca 2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca 2+] .
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- HY-D2856C
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Fluorescent Dye
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FITC-PEG5000-Br is a fluorescent dye composed of FITC (HY-66019), PEG and chlorine (-Cl). The chlorine group is an electrophilic active group that can be used for nucleophilic substitution reactions and facilitate subsequent chemical modification (Ex/Em=488/525 nm).
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- HY-D0041
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|
Calcein acetoxymethyl ester
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Fluorescent Dye
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Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
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- HY-D2224
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|
Fluorescent Dye
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Sulfo-Cy5.5 dUTP is a dUTP far-infrared fluorescent dye containing sulfonated Cyanine5.5 group .
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- HY-D1572
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Fluorescent Dye
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|
Carbostyril 165 is an electronically neutral fluorescent dye (Ex: 351/364 nm, Em: >400 nm) .
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- HY-134620
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Fluorescent Dye
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Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
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- HY-D2501
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|
Fluorescent Dye
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|
Sulfo Cy7-N3 is a Sulfo Cy7-azide, which is a fluorescent dye. Sulfo Cy7-N3 can be used in cell imagine by Click reaction. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D1085
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|
Fluorescent Dye
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AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
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- HY-D2607
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Fluorescent Dye
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|
ICG PEG5000 N3 is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG5000 N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=785/813 nm).
|
- HY-D2060
-
|
|
Fluorescent Dye
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
- HY-D0824A
-
|
Sulfo-Cyanine7 Succinimidyl Ester triethylamine
|
Fluorescent Dye
|
|
CY7-SE triethylamine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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- HY-D2851A
-
|
|
Fluorescent Dye
|
|
FITC-PEG-CHOL (MW 3400) is a fluorescent dye composed of FITC (HY-66019), PEG and cholesterol. FITC-PEG-CHOL (MW 5000) is widely used in cell membrane-related studies, liposome and nanoparticle modification, and biomolecule labeling (Ex/Em = 488/525 nm) .
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- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dye
|
|
Janelia Fluor® 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor® 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .\n
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- HY-138226
-
|
|
Fluorescent Dye
|
|
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
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- HY-D1113
-
|
|
Fluorescent Dye
|
|
TFAX 488,TFP is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,TFP yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
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- HY-DY3004
-
|
|
Fluorescent Dye
|
|
Frozen Section Embedding Medium is a water-soluble mixture of polyethylene glycol and polyvinyl alcohol, widely used in immunohistochemistry experiments. Frozen Section Embedding Medium supports tissue during frozen sectioning, increasing tissue continuity and reducing wrinkling and fragmentation.
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- HY-D2507
-
|
|
Fluorescent Dye
|
|
Cy3-PEG5000-NH2 is a polyethylene glycol derivative containing Cy3 (HY-D0822) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Cy3-PEG5000-NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling .
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- HY-D0030
-
|
|
Fluorescent Dye
|
|
2-Anthracenylsulfonyl chloride is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-P1362F
-
|
Cy5-Amyloid β Peptide (42-1)(human) Tris
|
Fluorescent Dye
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
- HY-W345148
-
|
|
Fluorescent Dye
|
|
2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc .
|
- HY-D0265
-
|
|
Fluorescent Dye
|
|
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .
|
- HY-D0896AR
-
|
NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)
|
Fluorescent Dye
|
|
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
- HY-W020030
-
|
|
Fluorescent Dye
|
|
4-Amino-3,6-disulfonaphthalic anhydride dipotassium is a building block that can be used to systhese a useful dye for biological research purposes.
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- HY-D1639A
-
- HY-D0896A
-
|
NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium
|
Fluorescent Dye
|
|
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
- HY-W354821
-
|
4-MUD
|
Fluorescent Dye
|
|
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .
|
- HY-W357142
-
|
|
Fluorescent Dye
|
|
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .
|
- HY-D2100
-
|
|
Fluorescent Dye
|
|
Cy5-DSPE is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
|
- HY-W440916
-
|
|
Fluorescent Dye
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Fluorescent Dye
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Fluorescent Dye
|
|
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
|
- HY-W142117
-
|
|
Fluorescent Dye
|
|
H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
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| Cat. No. |
Product Name |
Type |
-
- HY-108910
-
|
EC 3.4.21.1; Chymotrypsin A
|
Biochemical Assay Reagents
|
|
Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin downregulates the TLR4/NF-κB signaling pathway, inhibiting the release of inflammatory factors, reducing cell infiltration and tissue damage. It also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54) and can be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions. It can be used in research on diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin can be used in studies of inflammation, edema, and expectoration .
|
-
- HY-D0896
-
ANS
1 Publications Verification
ANSA; 8-Anilino-1-naphthalenesulfonic acid
|
Biochemical Assay Reagents
|
|
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×10 6 M -1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .
|
-
- HY-W007465
-
|
|
Biochemical Assay Reagents
|
|
4-Aminobenzyl alcohol is a self-eliminating linker. 4-Aminobenzyl alcohol can be used to synthesize the fluorescent probe MB-Van1 targeting Vanin-1 .
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-
- HY-150145A
-
|
|
Biochemical Assay Reagents
|
|
Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP .
|
-
- HY-D0155
-
|
|
Biochemical Assay Reagents
|
|
Zinpyr-1 is a zinc-responsive fluorescent indicator and a membrane-permeable metal-binding probe. Zinpyr-1 forms a complex with Mn 2+ ions and generates a fluorescence turn-on signal. Zinpyr-1 binds to free zinc ions in serum, enabling quantitative detection of free zinc concentration. Zinpyr-1 produces fluorescence signals reflecting the relative zinc concentration in plant root cells, localizes to specific layers of plant root cells, and can be used to support analyses related to plant zinc transporter mutations and homeostasis .
|
-
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Biochemical Assay Reagents
|
|
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
|
-
- HY-W011696
-
|
cis-1-Amino-9-octadecene, 80-90%
|
Biochemical Assay Reagents
|
|
Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a multifunctional reagent used for metal ion coordination and nanoparticle surface modification, and acts as a solvent, surfactant and reducing agent in the synthesis of metal oxide nanoparticles. Oleylamine, 80-90% regulates nanoparticle morphology, magnetization intensity and water proton relaxation rate via thiol-ene "click" reaction, and enhances the colloidal stability of nanoparticles in organic reagents. Oleylamine, 80-90% is mainly used in research and applications in fields such as nanomaterial synthesis, biomedical imaging (MRI contrast agents, fluorescent probes), cancer cell targeting and drug delivery .
|
-
- HY-112624I
-
|
Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
|
Biochemical Assay Reagents
|
|
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
|
-
- HY-W250727
-
|
6-(p-Tolylamino)naphthalene-2-sulfonate sodium
|
Biochemical Assay Reagents
|
|
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
|
-
- HY-34515
-
|
TMPhen; 3,4,7,8-Tetramethyl-1,10-phenanthroline
|
Biochemical Assay Reagents
|
|
3,4,7,8-Tetramethyl-1,10-phenanthroline (TMPhen) is an organic molecule commonly used as a ligand or catalyst. It has a wide range of applications in different fields, such as organometallic chemical reactions, electrochemical detection, and organic optoelectronic devices. Due to its excellent performance in fluorescent probes, biosensors and photocatalytic reactions, it has been widely used in research in the fields of chemistry and life sciences.
|
-
- HY-D1078
-
|
|
Biochemical Assay Reagents
|
|
5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC4 for MRP2 binding sites and inhibits MRP2-mediated LTC4 transport (Ex/Em = 496/525 nm) .
|
-
- HY-W090294
-
|
Peri-dinaphthalene (purified by sublimation)
|
Biochemical Assay Reagents
|
|
Perylene, which is a polycyclic aromatic hydrocarbon composed of four linearly fused benzene rings, is commonly used as a pigment and dye in a variety of applications, including printing inks, plastics, and textiles. In addition, Perylene has potential uses in solar cells as photosensitizers and as fluorescent probes in biochemistry and materials science. Perylene's rigid planar structure endows it with unique electronic and optical properties, making it a versatile and important compound in many fields of chemistry and materials science.
|
-
- HY-I0259
-
|
|
Biochemical Assay Reagents
|
|
8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .
|
-
- HY-158082B
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 40000
|
Biochemical Assay Reagents
|
|
TRITC-dextran (Tetramethyl rhodamine isothiocyanate glucan), MW 40000 is a TRITC (HY-D0791)-labeled neutral 40 kDa fluorescent polysaccharide probe. TRITC-dextran, MW 40000 forms a membrane layer on the surface of protocells composed of protamine/folate condensates, and is used to assess membrane fluidity via fluorescence recovery after photobleaching. TRITC-dextran, MW 40000 can also be used to evaluate the anti-bacterial invasion ability and colloidal stability of coated condensates, as well as analyze the permeability of vascular and lymphatic endothelial cell layers .
|
-
- HY-W073013
-
|
|
Biochemical Assay Reagents
|
|
5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II), commonly known as CoTPP or cobalt porphyrin, is a coordination compound. 5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II) is widely used in various fields such as catalysis, sensing, and organic electronics because of its unique electronic and optical properties. An efficient catalyst for reactions including oxidation, reduction, and CH bond activation, moreover, it has been used as a fluorescent probe for detecting oxygen content in biological systems and as an active material in organic solar cells.
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Biochemical Assay Reagents
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-59303
-
|
|
Biochemical Assay Reagents
|
|
1H-Imidazole-5-carboxaldehyde can be used as a chemical reagent in organic synthesis reactions. 1H-Imidazole-5-carboxaldehyde can be used to prepare other imidazole compounds, such as imidazole pyrimidine and imidazolone. 1H-Imidazole-5-carboxaldehyde can also be used as biochemical dyes and fluorescent probes.
|
-
- HY-150145
-
|
|
Biochemical Assay Reagents
|
|
Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .
|
-
- HY-W017232
-
|
p-Quinanisole
|
Biochemical Assay Reagents
|
|
6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
|
-
- HY-W035138
-
|
|
Biochemical Assay Reagents
|
|
Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins .
|
-
- HY-D0896A
-
|
NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium
|
Biochemical Assay Reagents
|
|
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
-
- HY-W440916
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-D2100
-
|
|
Biochemical Assay Reagents
|
|
Cy5-DSPE is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
|
-
- HY-121462
-
|
Quinoline Blue
|
Biochemical Assay Reagents
|
|
Cyanine is an excellent fluorescent core scaffold for constructing fluorescent probes. Covalent conjugation of Cyanine with other potent compounds can not only enhance their efficacy but also expand their application modes. Cyanine supports the development of cancer theranostic agents. Cyanine can be used in cancer research .
|
-
- HY-79602
-
|
|
Biochemical Assay Reagents
|
|
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .
|
-
- HY-D1021
-
|
Aminoallyl-dUTP sodium salt
|
Biochemical Assay Reagents
|
|
AA-dUTP (Aminoallyl-dUTP) sodium salt is a reverse transcriptase and DNA polymerase I substrate with probe precursor activity. AA-dUTP sodium salt undergoes enzymatic incorporation into DNA during cDNA synthesis and nick translation. AA-dUTP sodium salt generates amine-modified DNA, which can be used for labeling with amine-reactive fluorescent dyes .
|
-
- HY-118667
-
|
|
Biochemical Assay Reagents
|
|
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
|
-
- HY-W001952
-
|
|
Biochemical Assay Reagents
|
|
6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with β-cyclodextrin (β-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria .
|
-
- HY-D0265
-
|
|
Biochemical Assay Reagents
|
|
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .
|
-
- HY-W090065
-
|
1-Pyrenemethylamine hydrochloride
|
Biochemical Assay Reagents
|
|
Pyren-1-ylmethanamine hydrochloride, Pyren-1-ylmethanamine hydrochloride is commonly used as a fluorescent probe in biochemistry and molecular biology to detect and study nucleic acids, proteins and other biomolecules, moreover, it has been used in analytical chemistry Among them, for the detection of heavy metals and other pollutants in environmental samples, the pyrene group in the molecule exhibits strong fluorescence properties, which makes it useful as a sensitive and selective detector in various applications.
|
-
- HY-NP0144
-
|
WGA (Fluorescein)
|
Biochemical Assay Reagents
|
|
Succinylated Wheat Germ Agglutinin (Fluorescein) (WGA (Fluorescein)) is a fluorescent lectin that acts as a probe to specifically bind biomolecules. Succinylated Wheat Germ Agglutinin (Fluorescein) binds to cell surface glycoconjugates containing N-acetylglucosamine. Succinylated Wheat Germ Agglutinin (Fluorescein) is a selective agglutinating agent targeting specific red blood cells, thymocytes, splenocytes and lymphocytes. Succinylated Wheat Germ Agglutinin (Fluorescein) binds to fibroblasts and lymphocytes via dual binding sites in a temperature-dependent, saturable manner. Succinylated Wheat Germ Agglutinin (Fluorescein) can be used for quantitative studies of cell surface receptor glycoconjugates (Ex=495 nm, Em=515 nm) .
|
-
- HY-D0267
-
-
- HY-D0157
-
|
|
Biochemical Assay Reagents
|
|
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .
|
-
- HY-D0896AR
-
|
NSC 1746 ammonium (Standard); Peri acid, phenyl- ammonium (Standard); Phenyl peri acid ammonium (Standard)
|
Biochemical Assay Reagents
|
|
ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
|
-
- HY-W127775
-
-
- HY-141618
-
|
|
Biochemical Assay Reagents
|
|
5(6)-Carboxyrhodamine 110 is an amine-reactive fluorescent probe for labeling DNA, cells and proteins (Ex/Em = 498/530 nm) .
|
-
- HY-W441021
-
|
|
Biochemical Assay Reagents
|
|
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
|
-
- HY-150352
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
|
-
- HY-79602R
-
|
|
Biochemical Assay Reagents
|
|
p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .
|
-
- HY-W740363
-
|
5-AF hydrochloride
|
Biochemical Assay Reagents
|
|
5-Aminofluorescein hydrochloride (5-AF hydrochloride) is a protein fluorescent labeling reagent with excellent fluorescence activity. It is widely used in cell imaging and molecular probes in biomedical research. 5-Aminofluorescein hydrochloride can be used to observe the location of proteins and their dynamic changes, providing in-depth biological understanding. 5-Aminofluorescein hydrochloride is also used to detect interactions between biomolecules and help analyze complex biological processes.
|
-
- HY-D1639A
-
-
- HY-150352C
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH (MW 100 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352D
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH (MW 250 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352A
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH (MW 10 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352E
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH (MW 500 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
-
- HY-150352B
-
|
|
Biochemical Assay Reagents
|
|
Dextran-COOH (MW 70 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1002
-
|
Suc-LLVY-AMC
|
Fluorescent Dye
Proteasome
|
Others
|
|
Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .
|
-
- HY-136865
-
|
|
Fluorescent Dye
|
Others
|
|
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm) .
|
-
- HY-P1363F3
-
|
5-FAM-Amyloid β-peptide (1-42) (human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
|
-
- HY-P1005
-
-
- HY-P1004A
-
|
|
Fluorescent Dye
|
Others
|
|
Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Luciferase, firefly catalytic substrate is D-luciferin (HY-12591B) .
|
-
- HY-P2270
-
|
|
Fluorescent Dye
Arp2/3 Complex
|
Others
|
|
Phalloidin-TRITC is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
|
-
- HY-P2031
-
|
|
Arp2/3 Complex
|
Others
|
|
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
|
-
- HY-P1986
-
|
|
Caspase
|
Cancer
|
|
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
|
-
- HY-P3236
-
|
Ac-IEPD-pNA
|
Ser/Thr Protease
|
Cancer
|
|
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a colorimetric peptide substrate of granzyme B that allows accurate measurement of granzyme B activity .
|
-
- HY-P5287
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
|
-
- HY-P10943
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
APO-15 is a phosphatidylserine-binding fluorescent probe and apoptosis imaging reagent. APO-15 exhibits high chemical stability under proteolytic and oxidative conditions, enables quantification and imaging of drug-induced apoptosis in preclinical mouse models, and is applicable to fixed tissue samples and multiple in vivo administration routes (Ex = 488 nm; Em = 525 nm). APO-15 can be used in studies related to acute lung injury and breast cancer .
|
-
- HY-123051
-
-
- HY-P3749
-
|
|
Fluorescent Dye
|
Others
|
|
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .
|
-
- HY-P2536
-
-
- HY-111956B
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-P1169
-
|
|
Caspase
|
Others
|
|
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
|
-
- HY-P2065
-
|
|
Fluorescent Dye
|
Others
|
|
Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
|
-
- HY-P3484
-
|
|
MMP
|
Cancer
|
|
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .
|
-
- HY-P2270Y
-
|
|
Arp2/3 Complex
Fluorescent Dye
|
Others
|
|
Phalloidin-TRITC (solution) is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels .
|
-
- HY-P1362F
-
|
Cy5-Amyloid β Peptide (42-1)(human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
-
- HY-P10772
-
|
|
Peptide-Drug Conjugates (PDCs)
EBV
|
Cancer
|
|
L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM .
|
-
- HY-P10772A
-
|
|
Peptide-Drug Conjugates (PDCs)
EBV
|
Cancer
|
|
L2P4 TFA is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 TFA exhibits cytotoxicity in EBV-positive C666-1 cell with LC50 of 46.4 μM .
|
-
- HY-P3791
-
|
|
Fluorescent Dye
|
Others
|
|
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .
|
-
- HY-P2208
-
|
|
Fluorescent Dye
|
Cancer
|
|
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
|
-
- HY-111956
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-P5367
-
|
PMDM6-F
|
Fluorescent Dye
|
Others
|
|
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)
|
-
- HY-P11263
-
|
|
iGluR
|
Neurological Disease
|
|
AVLX-144 is a highly potent inhibitor of postsynaptic density protein 95 (PSD-95). AVLX-144 can be used as a template to develop imaging probes for postsynaptic density (PSD) molecules, and can be labeled with fluorine-18 (¹⁸F) or tritium (³H) to visualize PSD-95 in vivo. AVLX-144 can be utilized for the study of Parkinson's disease .
|
-
- HY-137834A
-
-
- HY-W142117
-
|
|
Fluorescent Dye
|
Others
|
|
H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM .
|
-
- HY-P5287A
-
|
|
Integrin
|
Cancer
|
|
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .
|
-
- HY-P11265
-
|
|
GnRH Receptor
Fluorescent Dye
|
Cancer
|
|
YQGN-7 is a targeted fluorescent probe for the gonadotropin-releasing hormone receptor (RnRHR). YQGN-7 exhibits high selectivity and affinity for breast cancer cells (KD = 217.8 nM). YQGN-7 achieves precise visualization of the primary and metastatic lesions of breast cancer by targeting the highly expressed GnRHR in tumor cells. YQGN-7 can be used in the research of breast cancer breast-conserving surgery (BCS) .
|
-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
- HY-D1532
-
|
|
Parasite
|
Others
|
|
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite .
|
-
- HY-P4703
-
|
|
Oxytocin Receptor
|
Others
|
|
Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro. Hydrin 1′ targets oxytocin receptor and derives a fluorescent probe of the oxytocin receptor .
|
-
- HY-P3362
-
|
|
Fluorescent Dye
|
Others
|
|
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
|
-
- HY-111956A
-
|
|
Fluorescent Dye
|
Cancer
|
|
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .
|
-
- HY-P2628
-
|
|
Fluorescent Dye
|
Others
|
|
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K + deprivation-induced apoptosis of cerebellar granule neurons .
|
-
- HY-P3475
-
|
|
Fluorescent Dye
|
Others
|
|
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
|
-
- HY-P11595
-
|
|
Fluorescent Dye
|
Cancer
|
|
TBZ-1 is a fluorescent probe that monitors the activity of immunoproteasome (Proteasome) (iCP) in cells. TBZ-1 undergoes fluorescence activation after being selectively cleaved by β5i, which is used for intracellular activity monitoring. TBZ-1 is applicable to cancer-related research .
|
-
- HY-P11637
-
|
|
Fluorescent Dye
|
Neurological Disease
|
|
Mitochondrial-targeted peptide BP19 is a fluorescent probe for the selective measurement of labile iron in the mitochondriairon. Mitochondrial-targeted peptide BP19 exhibits iron-selective sensing activity with mitochondrial accumulation, reduced fluorescence in iron-loaded cells, and fluorescence reinstatement upon iron chelation. Mitochondrial-targeted peptide BP19 evaluates mitochondrial labile iron levels in cultured fibroblasts with Friedreich's ataxia .
|
-
- HY-KD1029
-
|
|
|
Mito Red is a red-fluorescent fluorescent probe that specifically labels mitochondria in living mammalian cells.
|
-
- HY-KD1030
-
|
|
|
Tubulin Deep Red is a fluorescent probe with red fluorescence that can specifically label microtubules in living mammalian cells.
|
-
- HY-KD1027
-
|
|
|
Lyso Green is a fluorescent probe with green fluorescence for specific labeling of lysosomes in living mammalian cells.
|
-
- HY-K0320
-
Maximum Cited Publications
9 Publications Verification
|
|
MCE ROS Assay Kit utilizes the fluorescent probe DCFH-DA to detect ROS.
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P991650
-
|
|
PSMA
|
Cancer
|
|
MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .
|
-
(5)
-
- HY-P992459
-
|
|
ADC Antibody
Transmembrane Glycoprotein
|
Cancer
|
|
SGM-101 Antibody is a chimeric monoclonal antibody targeting carcinoembryonic antigen (CEA). SGM-101 Antibody can serve as a tumor-specific fluorescent imaging probe after being covalently conjugated with the near-infrared fluorescent dye BM104 . SGM-101 Antibody accumulates in CEA-positive tumor tissues via antigen-antibody specific binding, and emits near-infrared fluorescence to enable imaging of tumor lesions. SGM-101 Antibody can be used in research related to gastric cancer, colorectal cancer, pancreatic cancer, non-small cell lung cancer, breast cancer, peritoneal carcinomatosis, and liver metastases .
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N6716
-
-
-
- HY-18743
-
-
-
- HY-N7131
-
-
-
- HY-B1025
-
-
-
- HY-P1004
-
-
-
- HY-N16308
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes .
|
-
-
- HY-Y1309
-
-
-
- HY-B0315A
-
-
-
- HY-P2031
-
|
|
Structural Classification
Microorganisms
Classification of Application Fields
Ketones, Aldehydes, Acids
Other Diseases
Disease Research Fields
Source Classification
|
Arp2/3 Complex
|
|
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
|
-
-
- HY-D0226
-
-
-
- HY-W091541
-
-
-
- HY-N15875
-
-
-
- HY-118667
-
|
|
Microorganisms
Source Classification
|
Liposome
|
|
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
|
-
-
- HY-N2306R
-
-
-
- HY-N16309
-
|
|
Lipid
|
Fluorescent Dye
|
|
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.
|
-
-
- HY-N16571
-
|
|
Structural Classification
Flavonols
Flavonoids
Amaranthaceae
Plants
Source Classification
|
Fluorescent Dye
Endogenous Metabolite
|
|
Marionol is a type of flavonol compound and belongs to the secondary metabolites of plants. Marionol exhibits significant specificity towards Cu²⁺ and possesses the characteristic of intramolecular proton transfer in excited state (ESIPT), enabling it to generate strong fluorescence upon excitation by ultraviolet light. The maximum excitation/emission wavelengths are 350 nm and 510 nm (depending on the solvent), respectively. Marionol can be used as a fluorescence probe for Cu²⁺ .
|
-
-
- HY-N16325
-
|
|
Lipid
|
Fluorescent Dye
|
|
Golgi-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Golgi-Laurdanmimics the structure NBD C6 Ceramide that can be used for the study of the Golgi apparatus .
|
-
-
- HY-N16300
-
|
|
Lipid
|
Fluorescent Dye
|
|
Mito-laurdan bromide, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Mito-laurdan bromide contains a cationic triphenylphosphonium moiety, which accumulates at the inner mitochondrial membrane due to its negative membrane potential, connected via a 3 carbon linker .
|
-
-
- HY-165424
-
-
-
- HY-Y1309R
-
-
-
- HY-N16306
-
|
|
Lipid
|
Fluorescent Dye
|
|
Lyso-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Lyso-Laurdan accumulates in the lysosome via a morpholine group that is entrapped in lysosome via protonation to its cationic form in the acidic compartment. Lyso-laurdan is localized to lysosomes, allowing for the study of lysosomal membranes .
|
-
-
- HY-D0226R
-
-
-
- HY-B1025R
-
-
-
- HY-W091541R
-
-
-
- HY-N7131R
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-79602S1
-
|
|
|
p-Toluenesulfonamide- 15N is the 15N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .
|
-
-
- HY-B1422S
-
|
|
|
9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
-
- HY-W008048S
-
|
|
|
2',3'-O-Isopropylideneadenosine- 13C5 is the 13C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
|
-
-
- HY-Y1309S1
-
|
|
|
1-Naphthol-d7 (Furro ER-d7) is the deuterium labeled Naphthol (HY-Y1309). 1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media .
|
-
-
- HY-Y1309S
-
|
|
|
1-Naphthol-d8 is the deuterium labeled 1-Naphthol . 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe .
|
-
-
- HY-124197S
-
|
|
|
Coumarin hydrazine-d7 is the deuterium labeled Coumarin hydrazine (HY-124197). Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-D1068
-
|
DBCO-Sulfo-Cy5
|
|
DBCO
Labeling and Fluorescence Imaging
|
|
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR)red fluorescent dye with λabsand λem of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151708
-
|
|
|
Labeling and Fluorescence Imaging
Azide
|
|
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1583
-
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DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate
|
|
DBCO
|
|
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
|
-
- HY-145746
-
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|
|
Azide
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
|
-
- HY-128676
-
|
H-L-Lys(Poc)-OH hydrochloride
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1506
-
|
|
|
Labeling and Fluorescence Imaging
|
|
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-159529
-
|
DBCO-PEG4-Eosin Y
|
|
DBCO
|
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.
|
-
- HY-119323
-
|
|
|
Labeling and Fluorescence Imaging
Azide
|
|
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H2S). In the presence of H2S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H2S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .
|
-
- HY-D1269
-
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|
|
Azide
Labeling and Fluorescence Imaging
|
|
Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups . Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm).
|
-
- HY-D2171A
-
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|
|
DBCO
|
|
AF488 DBCO ditriethylamineis a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO ditriethylaminemediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
-
- HY-D1051
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid. Cy3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 548/563 nm).
|
-
- HY-D2769
-
|
Difluorocarboxyfluorescein azide, 6-isomer
|
|
Azide
|
|
Oregon green 488 azide (Difluorocarboxyfluorescein azide, 6-isomer) is a bright green fluorescent azide-activated probe that reacts with terminal alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). Oregon green 488 azide can label goat anti-mouse IgG and exhibits excellent luminescence efficiency. Oregon green 488 azide, as a streptavidin conjugate, is used for flow cytometry staining of macrophages .
|
-
- HY-D1668
-
|
|
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Labeling and Fluorescence Imaging
|
|
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .
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-
- HY-151662
-
|
N3-TFBA
|
|
Azide
|
|
4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-110128
-
|
SF7-AM
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Sulfidefluor 7-AM is a stable hydrogen sulphide (H2S) fluorescent probe . Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-D2746
-
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|
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Azide
|
|
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
|
-
- HY-137042
-
|
Alkyne-Cy5
|
|
Labeling and Fluorescence Imaging
Alkynes
|
|
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-W878943
-
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|
Azide
|
|
FAM azide, 5-isomer is a Click Chemistry labeling reagent.
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-
- HY-151776
-
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TZ-Cy3
|
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Tetrazine
Labeling and Fluorescence Imaging
|
|
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .
|
-
- HY-139014
-
|
H-L-Lys(Poc)-OH
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2443
-
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|
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DBCO
|
|
AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .
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-
- HY-135835
-
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|
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Azide
Labeling and Fluorescence Imaging
|
|
6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide . 6-FAM-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-D2616
-
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DBCO
|
|
ICG PEG2000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG2000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
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-
- HY-D2617
-
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|
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DBCO
|
|
ICG PEG5000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG5000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).
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- HY-D1274C
-
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Azide
|
|
Sulfo-cyanine3 azide potassium is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide potassium can be used for synthesis of fused tricyclic heterocycles, producing immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D2177
-
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|
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Azide
|
|
AF 555 azide is a fluorescent dye and is the azide of AF 555. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 555/565 nm) .
|
-
- HY-156305
-
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|
|
Labeling and Fluorescence Imaging
BCN
|
|
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.
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-
- HY-139337
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|
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Alkynes
|
|
SMCy5.5 is a SMCy dye (ex. 638 nm; em. 705 nm). The high brightness of SMCy5.5 allows for effective tracking and imaging of lipid droplet exchange between adipocytes. SMCy5.5 can be used for lipid droplet labeling studies .
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-
- HY-D1721
-
|
|
|
Labeling and Fluorescence Imaging
|
|
Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .
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-
- HY-D1622
-
|
Cy3-DBCO hexafluorophosphate
|
|
DBCO
|
|
Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.
|
-
- HY-D2871
-
|
|
|
Alkynes
|
|
DAyne is a Dopamine (DA)-mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAyne is promising for research of Parkinson’s disease (PD), particularly neurotoxicity, protein modification, and related pathways (e.g., endoplasmic reticulum stress, cytoskeletal instability) caused by dopamine dysregulation .
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-
- HY-D2289
-
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|
|
Azide
|
|
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .
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-
- HY-D1625
-
|
|
|
DBCO
Labeling and Fluorescence Imaging
|
|
Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free "Click Chemistry" reaction . Cy5 DBCO (chloride) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151701
-
-
- HY-D2744
-
|
|
|
TCO
|
|
BP Fluor 488 TCO reacts with tetrazines to produce a stable, covalent linkage, also referred to as the inverse-electron demand Diels-Alder cycloaddition reaction. This reaction is extremely fast (k > 800 M-1 s-1), selective, biocompatible, and does not require Cu-catalyst or elevated temperatures. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
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-
- HY-D2147
-
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|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy5-PEG7-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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-
- HY-135639
-
|
|
|
Labeling and Fluorescence Imaging
Alkynes
|
|
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D2756
-
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|
|
Alkynes
|
|
OG 488 alkyne is a bright, green-fluorescent alkyne-activated probe routinely used for imaging of azide-containing biomolecules. OG 488 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
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-
- HY-151704
-
|
|
|
Alkynes
|
|
ICG-alkyne is a short-wave infrared (SWIR)-emitting cyanine fluorescent probe based on alkyne-derivatized indocyanine green. ICG-alkyne can undergo click chemistry reaction to conjugate with antibody molecules via binding to the azide groups introduced into antibodies. ICG-alkyne enables SWIR fluorescent molecular imaging of breast tumors in living mice. ICG-alkyne can be used in breast cancer-related research .
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-
- HY-D1274
-
|
|
|
Azide
|
|
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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-
- HY-D1274A
-
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|
|
Labeling and Fluorescence Imaging
Azide
|
|
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D2242
-
|
|
|
DBCO
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
-
- HY-D1860
-
|
|
|
Alkynes
|
|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-W879228
-
|
|
|
DBCO
|
|
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence .
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-
- HY-D1354
-
|
|
|
Azide
|
|
Azide MegaStokes dye 673 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D2142
-
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|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy5-PEG2-TCO is a fluorescent dye that reacts with tetrazines. Cy5-PEG2-TCO contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-131024
-
|
JF549, Tetrazine
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-162129
-
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|
|
Azide
|
|
Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .
|
-
- HY-W800698
-
|
|
|
Alkynes
|
|
BP Fluor 430 Alkyne is a green-fluorescent alkyne-activated probe routinely used for imaging of moderate to high abundance azide-containing biomolecules. BP Fluor 430 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near 430 nm. This probe is water-soluble and its fluorescence is pH independent over a wide pH range.
|
-
- HY-D2287
-
|
|
|
Azide
|
|
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
- HY-D2287A
-
|
|
|
Azide
|
|
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
|
- HY-D2288
-
|
|
|
Azide
|
|
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .
|
- HY-D2549
-
|
|
|
DBCO
|
|
Cy5-PEG5000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D2548
-
|
|
|
DBCO
|
|
Cy5-PEG2000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D2522
-
|
|
|
DBCO
|
|
Cy3-PEG5000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-D2521
-
|
|
|
DBCO
|
|
Cy3-PEG2000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-D2572
-
|
|
|
DBCO
|
|
Cy5.5-PEG5000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D1274B
-
|
|
|
Azide
|
|
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1361
-
|
|
|
Alkynes
|
|
Alkyne cyanine dye 718 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-155324
-
|
|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy3-PEG7-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-D2342
-
|
|
|
Alkynes
|
|
SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells .
|
- HY-D2758
-
|
|
|
DBCO
|
|
TAMRA DBCO, 5-isomer is a derivative of tetramethylrhodamine (TMR, TAMRA) containing a cyclooctyne moiety (dibenzocyclooctyne, DBCO). Pure 5-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction (SPAAC)). TAMRA DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups.
|
- HY-D1548
-
|
|
|
Labeling and Fluorescence Imaging
Azide
|
|
1-(Azidomethyl)pyrene is a fluorescent dye . 1-(Azidomethyl)pyrene is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1307A
-
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Alkynes
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
- HY-D2139
-
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Alkynes
Labeling and Fluorescence Imaging
|
|
Cy3-PEG3-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151757
-
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Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .
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- HY-D2230
-
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Alkynes
|
|
Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .
|
- HY-D2217
-
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Tetrazine
|
|
Cy7 tetrazine is a near infrared dye that can be used for in vivo imaging .
|
- HY-D2219
-
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|
Tetrazine
|
|
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .
|
- HY-151756
-
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|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .
|
- HY-W879008
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Azide
|
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DiSulfo-ICG-azide disodium is a fluorescent dye.
|
- HY-130768
-
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Azide
PROTAC Synthesis
|
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N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties. N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1350
-
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Alkynes
|
|
5-ROX-alkyne is a rhodamine dye that labels DNA fragments. It enables visualization of the results of capillary electrophoresis genotyping experiments and gel shift experiments.
|
- HY-151753
-
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Alkynes
Labeling and Fluorescence Imaging
|
|
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
|
- HY-D2134
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Cy5-PEG3-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D1862
-
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|
|
Alkynes
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D1358
-
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|
|
Alkynes
|
|
Alkyne MegaStokes dye 608 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1357
-
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|
Alkynes
|
|
Alkyne MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D2141
-
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|
Alkynes
Labeling and Fluorescence Imaging
|
|
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W414549
-
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|
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Alkynes
|
|
FAM alkyne, 6-isomer is a click chemistry regent that can be used in 1,3-dipolar cycloaddition with azido-labeled compound .
|
- HY-D2802A
-
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|
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Azide
|
|
FITC-PEG1000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG1000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2499
-
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|
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DBCO
|
|
Sulfo Cy7 DBCO potassium is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. Sulfo Cy7 DBCO potassium is a click chemistry reagent. Sulfo Cy7 DBCO potassium contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-D2240
-
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DBCO
|
|
Sulfo-Cy3.5-DBCO is a fluorescent dye. Sulfo-Cy3.5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-156309
-
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Labeling and Fluorescence Imaging
Tetrazine
|
|
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D1850
-
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|
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Azide
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1593
-
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|
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Alkynes
Labeling and Fluorescence Imaging
|
|
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.
|
- HY-155325
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Cy3-PEG2-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-D2144
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Cy5-PEG7-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D2146
-
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|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy5-PEG3-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-155326
-
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|
|
Labeling and Fluorescence Imaging
TCO
|
|
Cy3-PEG3-TCO4 is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO4 can use its own TCO group to perform the inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-D2145
-
|
|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy5-PEG2-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 2 PEG units. Cy5-PEG2-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D2740
-
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|
|
Azide
|
|
ROX azide, 6-isomer is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
|
- HY-D2571
-
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|
|
DBCO
|
|
Cy5.5-PEG2000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D3266
-
|
|
|
DBCO
|
|
IR 650 DBCO is a far-red-fluorescent probe, pH-insensitive, azide-reactive probe routinely used for imaging of azide-containing biomolecules without the need for a copper catalyst. (Ex=651nm, Em=668 nm)
|
- HY-D3216
-
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|
|
Azide
|
|
ER-Cu (II) is an endoplasmic reticulum-selective fluorescent Cu 2+ probe. ER-Cu (II) localizes specifically to the endoplasmic reticulum of hepatocytes .
|
- HY-W800694
-
|
|
|
Alkynes
|
|
BP Fluor 405 alkyne triTEA is a blue-fluorescent dye that often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. A probe for copper-less detection (BP Fluor 405 DBCO) is also available for application where the presence of copper is not acceptable.
|
- HY-D3253
-
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|
|
Azide
|
|
IR 650 azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 azide is a terminal azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 633nm, Em = 647nm)
|
- HY-D3265
-
|
|
|
Alkynes
|
|
IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm
|
- HY-D3254
-
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|
|
Azide
|
|
IR 650 picolyl azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 picolyl azide is a terminal picolyl azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 650nm, Em = 670nm)
|
- HY-W840196
-
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|
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Alkynes
|
|
Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
- HY-155322
-
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|
|
Labeling and Fluorescence Imaging
TCO
|
|
Cy3-PEG2-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-151710
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2173
-
|
|
|
Azide
|
|
AF488 azide is a fluorescent dye that can be used to determine the reactivity of immobilized DIBO groups. AF488 azide exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-W400925
-
|
|
|
Azide
|
|
Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-W998675
-
|
|
|
Tetrazine
|
|
5-FITC-Tetrazine is an fluorescent dye composed of FITC (HY-66019) and Tetrazine. 5-FITC-Tetrazine can be used for fluorescent labeling and imaging .
|
- HY-W879007
-
|
|
|
Azide
|
|
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .
|
- HY-D2138
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Cy3-PEG7-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 7 PEG units. Cy3-PEG7-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1312
-
|
|
|
Azide
|
|
Pyrene azide 2 is a compound derived from pyreneacetic acid, connecting a fluorescent pyrene molecule by a PEG2 linker. The PEG units improve the water solubility of the compound.
|
- HY-D1920
-
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|
|
Azide
|
|
ATTO 390 azide is an azide derivative of ATTO 390 with excitation/emission maxima at 390/476 nm. ATTO 390 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151712
-
|
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.
|
- HY-D2241
-
|
|
|
DBCO
|
|
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .
|
- HY-D2802B
-
|
|
|
Azide
|
|
FITC-PEG3400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG3400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2121
-
|
|
|
Labeling and Fluorescence Imaging
BCN
|
|
Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-D2847B
-
|
|
|
DBCO
|
|
FITC-PEG5000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
|
- HY-D2112
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2179
-
|
|
|
DBCO
|
|
AF 568 DBCO is a fluorescent dye that reacts with azide-labeled molecules or biomolecules via copper-free click chemistry. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
|
- HY-D2750
-
|
|
|
Azide
|
|
Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
|
- HY-D1598
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2248
-
|
|
|
TCO
|
|
ICG-TCO is a fluorescent dye coupled by Indocyanine Green (ICG) and TCO. ICG-TCO can be used for detection and visualization of tetrazine-containing molecules.
|
- HY-D2117
-
|
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2200
-
|
|
|
DBCO
|
|
Cy5.5(Me)-C3-DBCO is a click chemistry reagent containing an cycloalkynes group. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .
|
- HY-D1053
-
|
Sulfo-Cyanine7-N3
|
|
Azide
Labeling and Fluorescence Imaging
|
|
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-W879342
-
|
|
|
Tetrazine
|
|
ICG-Tetrazine is a fluorescent dye .
|
- HY-D1052
-
|
|
|
Labeling and Fluorescence Imaging
Alkynes
|
|
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D2161
-
|
|
|
Azide
|
|
AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
|
- HY-D2111
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D1316
-
|
|
|
Azide
|
|
Cyanine7 azide chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-D2140
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
Cy3-PEG4-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 4 PEG units. Cy3-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D2118
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
TAMRA-PEG3-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-155323
-
|
|
|
TCO
Labeling and Fluorescence Imaging
|
|
Cy3-PEG3-TCO is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-TCO can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-156303
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D2121A
-
|
|
|
BCN
Labeling and Fluorescence Imaging
|
|
Cy3-PEG7-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-D1306
-
|
|
|
Azide
|
|
TAMRA azide, 6-isomer is an isomer of TAMRA. TAMRA azide, 6-isomer is the linker of TAMRA.
|
- HY-D2847A
-
|
|
|
DBCO
|
|
FITC-PEG3400-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
|
- HY-D1482
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
- HY-D2802D
-
|
|
|
Azide
|
|
FITC-PEG10000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W879370
-
|
|
|
Alkynes
|
|
Disulfo-ICG-alkyne disodium is a click chemistry reagent.
|
- HY-D2167
-
|
|
|
Alkynes
|
|
AF 568 alkyne is a derivative of the orange fluorescent dye AF 568. AF 568 has an absorption wavelength of 590-720 nm (FRET) and an emission wavelength of 515-720 nm. AF 568 alkyne can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the Alkyne group and molecules containing Azide groups. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D1356
-
|
|
|
Azide
|
|
Azide MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1557
-
|
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2748
-
|
|
|
Azide
|
|
5-JOE azide is a fluorescent dye with the emission in yellow region of the spectrum. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
- HY-D1304
-
|
|
|
Azide
|
|
Alexa fluor 488 azide ditriethylamine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-163140
-
|
|
|
Alkynes
|
|
BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction .
|
- HY-D2136
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Cy3-PEG2-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 2 PEG units. Cy3-PEG2-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2077
-
|
|
|
Azide
|
|
ATTO 725 azide is an azide derivative of ATTO 725 with excitation/emission maxima at 728/751 nm. ATTO 725 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151711
-
|
|
|
Labeling and Fluorescence Imaging
Azide
|
|
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D2802C
-
|
|
|
Azide
|
|
FITC-PEG5000-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-156304
-
|
|
|
TCO
Labeling and Fluorescence Imaging
|
|
Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D1313
-
|
|
|
Azide
|
|
PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-D1307
-
|
|
|
Alkynes
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
- HY-131021
-
|
JF549, Azide
|
|
Labeling and Fluorescence Imaging
Azide
|
|
Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-155327
-
|
|
|
Labeling and Fluorescence Imaging
BCN
|
|
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-155438
-
|
|
|
Azide
|
|
Mal-Cz is a maltose-derived fluorescence-on imaging probe for the detection of E. coli and Staphylococcus aureus . It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1893
-
|
|
|
Azide
|
|
HEX azide, 6-isomer, a derivate of fluorescent dye hexachlorofluorescein (HEX), can be used for labeling oligonucleotides .
|
- HY-155327A
-
|
|
|
Labeling and Fluorescence Imaging
BCN
|
|
Cy3-PEG2-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-D2159
-
|
|
|
Tetrazine
|
|
Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2137
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Cy3-PEG3-Azide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative containing 3 PEG units. Cy3-PEG3-Azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-131027
-
|
JF646, Azide
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Janelia Fluor 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor 646, Azide can be used for live-cell imaging experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1859
-
|
|
|
Alkynes
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
- HY-D2116
-
|
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2114
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D1327
-
|
|
|
Azide
Labeling and Fluorescence Imaging
|
|
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm) [1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2759
-
|
|
|
Azide
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
|
- HY-D2120A
-
|
|
|
Labeling and Fluorescence Imaging
BCN
|
|
Cy3-PEG3-exo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-D2149
-
|
|
|
BCN
|
|
Cy5-PEG7-exo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-exo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-138659
-
|
JF646, Tetrazine
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
|
Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor? 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-D2171
-
|
|
|
DBCO
|
|
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .
|
- HY-151713
-
|
|
|
Tetrazine
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .
|
- HY-D2579
-
|
|
|
DBCO
|
|
Sulfo DBCO-UBQ-2 is a click chemistry reagent combining a dark quencher, UBQ-2, with a polyaromatic-azo backbone, offering no native emission. UBQ-2 effectively quenches fluorescence in the 560-670 nm range, ideal for qPCR probes and FRET applications with orange to far-red dyes .
|
- HY-D2148
-
|
|
|
Tetrazine
|
|
AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D1349
-
|
|
|
Alkynes
|
|
Bodipy TR alkyneis one of a boron dipyrromethene fluorophore for the ROX (Texas Red) channel. This is a versatile fluorophore that can be used in microscopy, fluorescence polarization measurements, and other applications. This derivative is a terminal alkyne of copper-catalyzed click chemistry.
|
- HY-D2033
-
|
|
|
Azide
|
|
ATTO 514 azide is an azide derivative of ATTO 514 with excitation/emission maxima at 511/531 nm. ATTO 514 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2910
-
|
|
|
Alkynes
|
|
Ox4 is a selective covalent modifier targeting Methionine residues. Ox4 is promising for research of protein functionalization, antibody-drug conjugate (ADC) synthesis, and proteome-wide identification of reactive methionine sites .
|
- HY-D1555
-
|
Cy7 DBCO
|
|
DBCO
|
|
Cyanine7 DBCO (Cy7 DBCO) is a near-infrared fluorescent dye and an efficient bio-orthogonal quencher. Cyanine7 DBCO is formed by covalent connection of the near-infrared fluorescent dye Cy7 and the dibenzocyclooctyne (DBCO) functional group. After reacting with N3-Cy5-COOH, the fluorescence of Cy5 decreases by 90% within 90 minutes, and rapid signal attenuation can be observed within 2-5 minutes. Cyanine7 DBCO can be used for the study of deep tissue imaging and receptor-targeted therapeutic strategies .
|
- HY-D1725
-
|
|
|
Labeling and Fluorescence Imaging
|
|
Cy3-dCTP is a directly fluorescently labeled deoxyribonucleotide, in which Cy3 is a cyanine fluorescent dye. Cy3-dCTP is used for direct enzymatic labeling of DNA and cDNA: with the aid of DNA polymerases, this modified nucleotide is incorporated into the extending DNA strand during processes such as reverse transcription, PCR, nick translation or random primer labeling .
|
- HY-151701A
-
|
|
|
Alkynes
|
|
DiSulfo-Cy5 alkyne TEA is a fluorescent dye can be used as a click chemistry reagent .
|
- HY-D2156
-
|
|
|
Azide
|
|
AF 430 azide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 azide can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) via the azide group and molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. To achieve specific coupling of dye labels and biomolecules .
|
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
|
DBCO
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
|
- HY-D2243
-
|
|
|
Tetrazine
|
|
Cy3.5 tetrazineis a Tetrazine modified Cy3.5 fluorescent dye. SiR-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
|
- HY-D2743
-
|
|
|
Alkynes
|
|
ROX alkyne, 6-isomer is an alkyne derivative of the bright red-emitting dye ROX (Rhodamine X, Rhodamine 101). Due to its quantum yield approaching unity, ROX is a popular dye for qPCR and microscopy applications. It is used for fluorescent labeling of azide-containing biomolecules via copper-catalyzed click reaction.
|
- HY-D2113
-
|
|
|
Alkynes
Labeling and Fluorescence Imaging
|
|
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-D2847
-
|
|
|
DBCO
|
|
FITC-PEG2000-DBCO is a fluorescent dye composed of FITC (HY-66019), PEG and dibenzocyclooctyne (DBCO). DBCO is a cycloalkyne that can react with molecules containing azide groups through "click chemistry" to achieve coupling (Ex/Em=488/525 nm).
|
- HY-W588722
-
|
|
|
DBCO
|
|
ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
|
- HY-D1069
-
|
DBCO-Sulfo-Cy3
|
|
DBCO
Labeling and Fluorescence Imaging
|
|
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-D2500
-
|
|
|
DBCO
|
|
CY7 DBCO chloride is a dye derivative of CY7 (HY-D0825) bearing a DBCO group. CY7 DBCO chloride is a click chemistry reagent. CY7 DBCO chloride contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-120317
-
|
|
|
Alkynes
|
|
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .
|
- HY-D1944
-
|
|
|
Azide
|
|
ATTO 590 Azide is an azide derivative of ATTO 590 with excitation/emission maxima at 594/622 nm. ATTO 590 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2143
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
|
- HY-D2802
-
|
|
|
Azide
|
|
FITC-PEG400-N3 is an azide fluorescent dye containing polyethylene glycol (PEG) and FITC (HY-66019). FITC-PEG400-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D2120
-
|
|
|
Labeling and Fluorescence Imaging
BCN
|
|
Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-D1930
-
|
|
|
Azide
|
|
ATTO 425 Azide is an azide derivative of ATTO 425, the maximum excitation and emission wavelength: 439/489 nm. ATTO 425 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-D1355
-
|
|
|
Azide
|
|
Azide cyanine dye 728 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
- HY-156306
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
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| Cat. No. |
Product Name |
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Classification |
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- HY-125746
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Cholesterol
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BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
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- HY-D1378
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Fluorescent Lipids
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C-Laurdan is a modified Laurdan (HY-D0080) probe that imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan can be used in research of lipid arrangement and fluidity in biological membranes or artificial lipid membranes .
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- HY-162543
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18:1 Lissamine rhodamine PE
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Phospholipids
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18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .
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- HY-150150F
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siRNAs
siRNA drugs
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Cy3-siRNA Negative Control is Cy3-labeled SiRNA Negative Control (HY-150150). Cy3-siRNA Negative Control can be used for easy visualization and assessment of transfection efficiency.
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- HY-R04602F
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MicroRNAs
miRNA mimics
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FAM-MicroRNA Mimic Negative Control is a FAM labeled FAM-MicroRNA Mimic Negative Control (HY-R04602). MicroRNA Mimic Negative Control is a miRNA mimic of 21-nucleotides, and can be used as a negative control. The sequence of MicroRNA Mimic Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.
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- HY-W008048
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Nucleoside Analogs
Adenosine
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2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
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- HY-W440914
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG1000-FITC is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research use only.
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- HY-W440916
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG3400-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-D2100
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Fluorescent Lipids
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Cy5-DSPE is a far-infrared fluorescent phospholipid (λex/λem = 600/665 nm). Cy5-DSPE is used to label liposomes, membranes and lipid nanoparticles, and can be applied to tracking and imaging studies of liposomes .
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- HY-118667
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Cholesterol
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Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .
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- HY-DY1029
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Cholesterol
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BODIPY-cholesterol (solution) is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
Solvent and concentration: DMSO: 1 mM
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- HY-159194
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .
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- HY-W010947
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Fluorescent Lipids
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4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .
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- HY-D2284
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Sphingosine-1-phosphate lyase fluorogenic substrate
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Fluorescent Lipids
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SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .
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- HY-D2762
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Fluorescent Lipids
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18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
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- HY-120993
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1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium
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Nucleotide Analogs
Adenine Nucleotide
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1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .
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- HY-151750
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Phosphoramidites
Uracil
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Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.
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- HY-D2525
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Fluorescent Lipids
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Cy3-PEG-DMPE is a fluorescent probe that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and DMPE (HY-142983). Cy3-PEG-DMPE is widely used in biomolecule labeling, cell imaging and liposome research.
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- HY-W441021
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Phospholipids
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DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
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- HY-172508
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Phosphoramidites
Uracil
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Perylene dU phosphoramidite is a bright and extremely photostable fluorescent polycyclic aromatic hydrocarbon (PAH) label with a quantum yield approaching quantitative. Due to the low lifetime of fluorescence, this probe does not form excimers.With this phosphoramidite, perylene can be introduced into DNA by automated oligonucleotide synthesis.
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- HY-160059
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Aptamers
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JHIT2e aptamer sodium is a molecular probe based on the aptamer JHIT2 of human liver cancer cell line HepG2 cells. JHIT2e aptamer sodiu retains the ability to specifically bind HepG2 and can deliver fluorescent materials or radionuclides to tumors .
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- HY-D2526
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Fluorescent Lipids
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Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2517
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Fluorescent Lipids
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Cy3-PEG5000-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG5000-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-D2516
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Fluorescent Lipids
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Cy3-PEG3400-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG3400-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-178588
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Nucleoside Analogs
Nucleotide Analogs
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Fluorescein-12-dUTP is a fluorescent labeling and detection reagent that can be used for nucleic acid synthesis. Fluorescein-12-dUTP can be used to synthesize labeled DNA probes for in situ hybridization, microarray or western blot analysis .
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- HY-D1884
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