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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
GAD
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "GAD" in MCE Product Catalog:
12
12 Publications Verification
Cat. No.: HY-B0161A
CAS No.: 136434-34-9
Synonyms: (S)-Duloxetine hydrochloride; LY-248686 hydrochloride
Target:
Research Areas:
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
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Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
1
Category:
Infection Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Disease Research Fields
Target:
1
Research Areas:
1
1 Cited Publications
Cat. No.: HY-W015595
CAS No.: 195316-72-4
Synonyms: L-2-Allylglycine hydrochloride
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P75178
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GAD2; Glutamate Decarboxylase 65 KDa Isoform; Glutamate Decarboxylase 2; GAD-65; GAD65; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kD); 65 KDa Glutamic Acid Decarboxylase; Glutamate Decarboxylase-2 (Pancreas); Glutamate Decarboxylase 2 (Pan
Species:
Mouse
Source:
Sf9 insect cells
Target:
Research Areas:
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) .
Cat. No.: HY-18715
CAS No.: 166734-83-4
Synonyms: (S)-Ornidazole; Levornidazole
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Research Areas:
Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents .
Cat. No.: HY-W012123
CAS No.: 90-50-6
Category:
Plant Polygala tenuifolia Willd. Extract Simple Phenylpropanols Polygalaceae Extract Phenylpropanoids Endogenous metabolite
Target:
Synonyms: BHV-4157; Trigriluzole
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Research Areas:
Troriluzole, a third-generation, tripeptide proagent of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD) .
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3-Methyl-GABA is a potent GABA aminotransferase activator. 3-Methyl-GABA can fit the binding pocket of GABAA receptor (GABAaR). 3-Methyl-GABA can activate L-glutamic acid decarboxylase (GAD). 3-Methyl-GABA has anticonvulsant activity .
Cat. No.: HY-W088011B
CAS No.: 2836-32-0
Synonyms: Sodium hydroxyacetate, 98%
Cat. No.: HY-W023493
CAS No.: 7685-44-1
Synonyms: 2-Aminopent-4-enoic acid
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Research Areas:
Research Areas:
SB 220025 is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 also inhibits p56 Lck and PKC with IC50 values of 3.5 and 2.89 µM, respectively. SB 220025 inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation .
Cat. No.: HY-P2525
CAS No.: 245124-26-9
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Cat. No.: HY-P5396A
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Cat. No.: HY-Y0367S
CAS No.: 24461-33-4
Synonyms: Maleic-2,3-d2 acid
Cat. No.: HY-B0161S
CAS No.: 919514-01-5
Cat. No.: HY-RS17368
Target:
Research Areas:
Gad1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gad1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990419
Target:
Research Areas:
Anti-GAD65 Antibody is a humanized antibody expressed in CHO cells that targets GAD65. The Anti-GAD65 Antibody has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 146.48 kDa. The isotype control for Anti-GAD65 Antibody can refer to Human IgG1 lambda, Isotype Control (HY-P99992).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
