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Troriluzole (Synonyms: BHV-4157)

Cat. No.: HY-122487
Handling Instructions

Troriluzole, a third-generation, tripeptide prodrug of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD).

For research use only. We do not sell to patients.

Troriluzole Chemical Structure

Troriluzole Chemical Structure

CAS No. : 1926203-09-9

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Description

Troriluzole, a third-generation, tripeptide prodrug of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD)[1][2].

IC50 & Target

glutamate[1]

In Vitro

Troriluzole is absorbed systemically and cleaves into riluzole by aminopeptidases[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

419.38

Formula

C₁₅H₁₆F₃N₅O₄S

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Troriluzole
Cat. No.:
HY-122487
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