GLUT2

Isoforms Recommended:	GLUT2

By Targets:	GLUT (8) Akt (1) Antibiotic (1) Apoptosis (1) Autophagy (1) Bacterial (1) Dipeptidyl Peptidase (1) Disulfidptosis (3) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (1) Drug Derivative (1) Endogenous Metabolite (2) Fluorescent Dye (1) NF-κB (2) Reference Standards (2) SGLT (1) Small Interfering RNA (siRNA) (3) SOD (2)
By Research Areas:	Cancer (6) Infection (1) Inflammation/Immunology (2) Metabolic Disease (7)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Targets Recommended: GLUT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13753

Streptozotocin 135+ Cited Publications Streptozocin; NSC-85998; U 9889	DNA/RNA Synthesis DNA Alkylator/Crosslinker Autophagy Bacterial Antibiotic Apoptosis	Infection Cancer
Streptozotocin (Streptozocin; STZ) is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells ^[2] .

HY-100017

BAY-876 50+ Cited Publications	GLUT Disulfidptosis	Cancer
BAY-876, a chemical probe, is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC₅₀ of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis ^[2] .

HY-145597

KL-11743 5 Publications Verification	GLUT Disulfidptosis	Metabolic Disease Cancer
KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC₅₀s of 115, 137, 90, and 68 nM for *GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death. In addition, KL-11743 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis* ^[2] .

HY-121401A

(−)-Myrtenal (1R)-(−)-Myrtenal; (−)-(1R,5S)-Myrtenal	Akt	Metabolic Disease Cancer
(-)-Myrtenal ((1R)-(-)-Myrtenal) is an orally active terpene with antitumour activity. (-)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats ^[2].

HY-W179181

MSNBA 1 Publications Verification	GLUT	Metabolic Disease Cancer
MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC₅₀ of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a K_i of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes .

HY-128447

Allyl methyl sulfide 1 Publications Verification	Endogenous Metabolite SOD NF-κB GLUT	Metabolic Disease Inflammation/Immunology
Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic *GLUT2* expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications ^[2] .

HY-128447R

Allyl methyl sulfide (Standard)	Reference Standards Endogenous Metabolite SOD NF-κB GLUT	Metabolic Disease Inflammation/Immunology
Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic *GLUT2* expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications ^[2] .

HY-D3199

NIR‐fluorescent glucose	Fluorescent Dye GLUT	Metabolic Disease
NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for *GLUT4* and *GLUT2* transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo .

HY-RS13164

SLC2A2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC2A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC2A2 Human Pre-designed siRNA Set A SLC2A2 Human Pre-designed siRNA Set A

HY-RS13166

Slc2a2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc2a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc2a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc2a2 Rat Pre-designed siRNA Set A Slc2a2 Rat Pre-designed siRNA Set A

HY-180784

Hypoglycemic agent 4	Drug Derivative Dipeptidyl Peptidase SGLT GLUT	Metabolic Disease
Hypoglycemic agent 4 (Compound 5b) is a tetrahydroacridine derivative with orally active hypoglycemic activity. Hypoglycemic agent 4 has a good binding affinity for the key diabetic targets: DPP-IV, SGLT1, and *GLUT2*. Hypoglycemic agent 4 can inhibit glucose diffusion. Hypoglycemic agent 4 can reduce fasting blood sugar in Streptozotocin (HY-13753)-induced diabetic rats and its effect is comparable to Gliclazide (HY-B0753). Hypoglycemic agent 4 can be used for research of type 2 diabetes .

HY-100017R

BAY-876 (Standard)	Reference Standards GLUT Disulfidptosis	Cancer
BAY-876 (Standard) is the analytical standard of BAY-876 (HY-100017). This product is intended for research and analytical applications. BAY-876, a chemical probe, is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis ^[2] .

HY-RS13165

Slc2a2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Slc2a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc2a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Slc2a2 Mouse Pre-designed siRNA Set A Slc2a2 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-D3199

NIR‐fluorescent glucose	Fluorescent Dye
NIR-fluorescent glucose is a functional glucose-based fluorescent imaging agent. Conjugated with the nitrobenzoselenadiazole-based SCOTfluor (compound 9), NIR-fluorescent glucose acts as a substrate for *GLUT4* and *GLUT2* transporters. NIR-fluorescent glucose enables the visualization of glucose uptake in live cells and in vivo .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13753

Streptozotocin 135+ Cited Publications Streptozocin; NSC-85998; U 9889	Structural Classification Microorganisms Classification of Application Fields Antibiotics Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification Cancer	DNA/RNA Synthesis DNA Alkylator/Crosslinker Autophagy Bacterial Antibiotic Apoptosis
Streptozotocin (Streptozocin; STZ) is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells ^[2] .

HY-121401A

(−)-Myrtenal (1R)-(−)-Myrtenal; (−)-(1R,5S)-Myrtenal	Other Monoterpenes Classification of Application Fields Terpenoids Labiatae Erythrina poeppigiana Metabolic Disease Plants Disease Research Fields Source Classification	Akt
(-)-Myrtenal ((1R)-(-)-Myrtenal) is an orally active terpene with antitumour activity. (-)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats ^[2].

HY-128447

Allyl methyl sulfide 1 Publications Verification	Infection Natural Products Liliaceae Classification of Application Fields Plants Endogenous metabolite Disease Research Fields A．Sativam L. var．Viviparum Regel Source Classification	Endogenous Metabolite SOD NF-κB GLUT
Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic *GLUT2* expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications ^[2] .

HY-128447R

Allyl methyl sulfide (Standard)	Structural Classification Natural Products Liliaceae Plants Endogenous metabolite A．Sativam L. var．Viviparum Regel Source Classification	Reference Standards Endogenous Metabolite SOD NF-κB GLUT
Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic *GLUT2* expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications ^[2] .

Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	IHC-P (1) WB (2) FC (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82924

	*Glucose Transporter GLUT2* Antibody (YA2669)** liver; Glucose Transporter 2; Glucose Transporter GLUT2; Glucose transporter type 2; Glucose transporter; liver/islet; GLUT2; GTT2; SLC2A2	WB	Human
	Glucose Transporter GLUT2 Antibody (YA2669) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose Transporter GLUT2.

HY-P80406

	*Glucose Transporter GLUT2* Antibody (YA408)** 1 Publications Verification	WB, IHC-P, FC	Human
	Glucose Transporter GLUT2 Antibody (YA408) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose Transporter GLUT2.

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Cat. No.	Product Name		Classification

HY-RS13164

SLC2A2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC2A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13166

Slc2a2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc2a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc2a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13165

Slc2a2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc2a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc2a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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