182 Results for "

Iodide

" in MedChemExpress (MCE) Product Catalog:
Products (182)

182 Results for "Iodide" in MCE Product Catalog:

160
160 Publications Verification
Cat. No.: HY-D0815
CAS No.: 25535-16-4
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
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88
88 Cited Publications
Cat. No.: HY-D0041
CAS No.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
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37
37 Cited Publications
Cat. No.: HY-W008719
CAS No.: 36913-39-0
Research Areas:  

Neurological Disease

MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT) .
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28
28 Cited Publications
Cat. No.: HY-101086
CAS No.: 2260-50-6
Purity:  98.59%
Synonyms: ACh Iodide
Acetylcholine iodide is a muscarinic receptor modulator. Acetylcholine iodide specifically binds to muscarinic receptors, inhibits sodium absorption, and induces chloride secretion. Acetylcholine iodide changes intestinal ion transport, enhances intestinal secretory function, induces or maintains mammary gland development and lactation. Acetylcholine iodide can be used for intestinal ion transport regulation and mammary gland physiological function research .
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19
19 Cited Publications
Cat. No.: HY-14614D
CAS No.: 3493-13-8
Synonyms: S-Adenosyl methionine Iodide; Ademetionine Iodide; AdoMet Iodide
S-Adenosyl-L-methionine (S-Adenosyl methionine) iodide is an orally active methyl group donor. S-Adenosyl-L-methionine iodide is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine iodide also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine iodide has the potential for, cancer, liver disease and osteoarthritis research .
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13
13 Cited Publications
Cat. No.: HY-N6791
CAS No.: 126643-37-6
KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with an Ki value of 0.23 μM, it also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively. KT5823 is a Staurosporine-related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na +/I - symporter) NIS expression, and iodide uptake in thyroid cells. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels of apoptotic DNA fragmentation .
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4
4 Cited Publications
Cat. No.: HY-15595A
CAS No.: 737763-37-0
Purity:  ≥98.0%
Synonyms: 360 A Iodide
Target:  

G-quadruplex Telomerase

Research Areas:  

Cancer

360A iodide is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.
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3
3 Cited Publications
Cat. No.: HY-W040258
CAS No.: 905-96-4
Synonyms: DiOC2(3)
Research Areas:  

Others

3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions .
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2
2 Cited Publications
Cat. No.: HY-122524A
CAS No.: 81100-62-1
7-Methylguanosine iodide is an iodide of 7-Methylguanosine (HY-122524). 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects .
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2
2 Cited Publications
Cat. No.: HY-148502
CAS No.: 2926782-31-0
Purity:  98.61%
Target:  

mAChR

Research Areas:  

Neurological Disease

VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA) .
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1
1 Cited Publications
Cat. No.: HY-D0084
CAS No.: 53213-82-4
Synonyms: DiOC6(3) Iodide
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine dye which can be used to monitor changes in mitochondrial membrane potential.
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1
1 Cited Publications
Cat. No.: HY-N0334A
CAS No.: 4277-43-4
Synonyms: Magnoflorine Iodide; α-Magnoflorine Iodide; Thalictrine Iodide
(+)-Magnoflorine (α-Magnoflorine) iodide is an orally active aporphine alkaloid with multiple biological activities. (+)-Magnoflorine iodide promotes Parkin/PINK1 -mediated mitochondrial autophagy, inhibits the activation of NLRP3/Caspase-1 pathway, regulates the intestinal microbiota, and exhibits significant anti-inflammatory and immunomodulatory activities. (+)-Magnoflorine iodide inhibits JNK and TLR4/NF-κB signaling pathways, activates Sirt1/AMPK pathway, alleviates neuronal oxidative stress and apoptosis. Magnoflorine upregulates miR-410-3p, inhibits HMGB1/NF-κB pathway, and has anti-tumor activity. (+)-Magnoflorine iodide also has significant antifungal activity .
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1
1 Cited Publications
Cat. No.: HY-107740
CAS No.: 977-96-8
Purity:  99.85%
Synonyms: 1,1'-Diethyl-2,2'-cyanine Iodide; Decynium 22; Diethylcyanine Iodide; Eastman 7851
Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, OCT2, OCT3) and plasma membrane monoamine transporter (PMAT). Pseudoisocyanine iodide has antidepressant activity .
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1
1 Cited Publications
Cat. No.: HY-107654
CAS No.: 24570-49-8
Purity:  ≥97.0%
Synonyms: (+)-Muscarine Iodide
Target:  

mAChR

Research Areas:  

Neurological Disease

Muscarine ((+)-Muscarine) iodide is a toxin that can stimulate the parasympathetic nervous system. Muscarine iodide is a prototype muscarinic acetylcholine receptor agonist .
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1
1 Cited Publications
Cat. No.: HY-W250307
CAS No.: 2217-79-0
Diphenyliodonium iodide is an inhibitor of reactive oxygen species (ROS). Diphenyliodonium iodide can inhibit the accumulation of bisdemethoxycurcumin in fresh-cut yam by inhibiting the phenylpropanoid pathway and the biosynthesis of bisdemethoxycurcumin, thereby preventing the yellowing of fresh-cut yam. Diphenyliodonium iodide can be used in medicine and fruit preservation .
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1
1 Cited Publications
Cat. No.: HY-W111907
CAS No.: 905-97-5
Target:  

Fluorescent Dye

Research Areas:  

Others

3,3-Diethylthiacarbocyanine iodide is a cyanine dye. 3,3-Diethylthiacarbocyanine iodide can be used in photochemical methods .
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1
1 Cited Publications
Cat. No.: HY-W009418
CAS No.: 6456-44-6
Synonyms: 1-Methylnicotinamide Iodide
TRIA-662 (1-Methylnicotinamide chloride) iodide is an endogenous metabolite. TRIA-662 iodide shows antithrombotic and anti-inflammatory activities .
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1
1 Cited Publications
Cat. No.: HY-135414B
Purity:  99.95%
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
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1
1 Cited Publications
Cat. No.: HY-K1092

MCE YO-PRO-1/PI Apoptosis and Necrosis Detection Kit is a dual-fluorescence method based on the green fluorescent dye YO-PRO-1 (YP1) and the red fluorescent dye Propidium Iodide (PI) for detecting cell apoptosis and necrosis.

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1
1 Cited Publications
Cat. No.: HY-34619
CAS No.: 27126-76-7
[Hydroxy(tosyloxy)iodo]benzene is a versatile reagent for the mild oxidation of aryl iodides at the iodine atom by ligand transfer. [Hydroxy(tosyloxy)iodo]benzene is an effective reagent for the one-step conversion of ketones to the corresponding α-tosyloxy ketones. [Hydroxy(tosyloxy)iodo]benzene is also a Bronsted acid and is expected to catalyze the enolization of ketones .
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