126 Results for "

Isoflavone

" in MedChemExpress (MCE) Product Catalog:
Products (126)

126 Results for "Isoflavone" in MCE Product Catalog:

Isoflavone
Isoflavone
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Cat. No.: HY-W006405
CAS No.: 574-12-9
Category:  

Flavonoids Glycine max (L.) merr Other Diseases Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Estrogen Receptor/ERR

Isoflavone is an orally available bioactive component of soy phytoestrogen with lipid-lowering and antioxidant activities. Isoflavone prevents a variety of chronic diseases by regulating fatty acid oxidation in the liver and gene expression in adipose tissue. In addition, isoflavone has important value in the research of cancer and cardiovascular diseases .
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94
Genistein
Genistein
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94 Publications Verification
Cat. No.: HY-14596
CAS No.: 446-72-0
Purity:  99.82%
Synonyms: NPI 031L
Category:  

Anti-aging Leguminosae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Glycine max (L.) merr Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer Isoflavones

Target:  

EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
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33
Puerarin
Puerarin
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33 Cited Publications
Cat. No.: HY-N0145
CAS No.: 3681-99-0
Category:  

Pueraria edulis Pampan. Flavonoids Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Cancer Isoflavones

Target:  

5-HT Receptor

Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption .
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27
Daidzein
Daidzein
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27 Cited Publications
Cat. No.: HY-N0019
CAS No.: 486-66-8
Category:  

Leguminosae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Glycine max (L.) merr Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Cancer Isoflavones

Target:  

PPAR Endogenous Metabolite

Daidzein is a soy isoflavone, which acts as a PPAR activator.
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13
Daidzin
Daidzin
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13 Cited Publications
Cat. No.: HY-N0018
CAS No.: 552-66-9
Synonyms: Daidzoside; NPI-031D; Daidzein 7-O-glucoside
Category:  

Flavonoids Monophenols Glycine max (L.) merr Other Diseases Phenols Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH)

Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .
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11
Genistin
Genistin
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11 Cited Publications
Cat. No.: HY-N0595
CAS No.: 529-59-9
Synonyms: Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
Category:  

Flavonoids Glycine max (L.) merr Metabolic Disease Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Estrogen Receptor/ERR Apoptosis

Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway .
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11
Ononin
Ononin
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11 Cited Publications
Cat. No.: HY-N0270
CAS No.: 486-62-4
Synonyms: Ononoside; Formononetin 7-O-β-D-glucopyranoside
Category:  

Flavonoids Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Leguminosae Extract Plants Other Families Extract Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

ERK JNK p38 MAPK PI3K Akt mTOR Apoptosis

Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy .
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8
Glycitin
Glycitin
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8 Cited Publications
Cat. No.: HY-N0012
CAS No.: 40246-10-4
Synonyms: Glycitein 7-O-β-glucoside
Category:  

Infection Flavonoids Monophenols Glycine max (L.) merr Phenols Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Bacterial

Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) .
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7
Glycitein
Glycitein
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7 Cited Publications
Cat. No.: HY-N0016
CAS No.: 40957-83-3
Synonyms: Glycetein
Category:  

Other disease Leguminosae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Glycine max (L.) merr Disease markers Phenols Polyphenols Disease Research Fields Cancer Isoflavones

Target:  

Apoptosis Autophagy

Glycitein is a soy isoflavone used to study apoptosis and antioxidant .
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5
Calycosin-7-O-β-D-glucoside
Calycosin-7-O-β-D-glucoside
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5 Cited Publications
Cat. No.: HY-N0520
CAS No.: 20633-67-4
Synonyms: Calycosin-7-glucoside
Category:  

Flavonoids Monophenols Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Phenols Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Reactive Oxygen Species (ROS)

Calycosin-7-O-β-D-glucoside is an isoflavone isolated from Astragali Radix. Calycosin-7-O-β-D-glucoside has variety of biological activities, such as neuroprotective, cardioprotection, anti-inflammation, and antioxidative stress effects .
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5
Prunetin
Prunetin
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5 Cited Publications
Cat. No.: HY-N2597
CAS No.: 552-59-0
Category:  

Leguminosae Extract Plants Trifolium pratense Linn. Flavonoids Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology Isoflavones

Target:  

Aldehyde Dehydrogenase (ALDH)

Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor .
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5
6''-O-Acetylglycitin
6''-O-Acetylglycitin
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5 Cited Publications
Cat. No.: HY-N4072
CAS No.: 134859-96-4
Category:  

Flavonoids Monophenols Glycine max (L.) merr Metabolic Disease Phenols Leguminosae Extract Plants Disease Research Fields Isoflavones

Target:  

Others

6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind .
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4
Sophoricoside
Sophoricoside
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4 Cited Publications
Cat. No.: HY-N0423
CAS No.: 152-95-4
Category:  

Flavonoids Sophora japonica (L.) Schott Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

Others

Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects.
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4
Irisflorentin
Irisflorentin
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4 Cited Publications
Cat. No.: HY-N0268
CAS No.: 41743-73-1
Category:  

Flavonoids Iridaceae Extract Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

NO Synthase

Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .
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4
7-Methoxyisoflavone
7-Methoxyisoflavone
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4 Cited Publications
Cat. No.: HY-N6631
CAS No.: 1621-56-3
Target:  

AMPK

Research Areas:  

Metabolic Disease Cancer

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
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3
5-Methyl-7-methoxyisoflavone
5-Methyl-7-methoxyisoflavone
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3 Cited Publications
Cat. No.: HY-N1993
CAS No.: 82517-12-2
Category:  

Flavonoids Metabolic Disease Plants Other Families Extract Disease Research Fields Isoflavones

Target:  

Cytochrome P450 NF-κB

5-Methyl-7-methoxyisoflavone is an orally active anti-oxidant with remyelinating activity. 5-Methyl-7-methoxyisoflavone inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. 5-Methyl-7-methoxyisoflavone is a non-steroidal anabolic isoflavone, used as a anabolic agent. 5-Methyl-7-methoxyisoflavone shows better potency increasing muscle mass and endurance than Ipriflavone (HY-N0094). 5-Methyl-7-methoxyisoflavone can be used for fat loss besides the maintenance of low cholesterol level and strengthen bones. 5-Methyl-7-methoxyisoflavone is the inhibitor for NF-κB .
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3
Wighteone
Wighteone
0 Images
3 Cited Publications
Cat. No.: HY-N1073
CAS No.: 51225-30-0
Synonyms: 6-Isopentenylgenistein; Erythrinin B
Category:  

Genista ephedroides DC. Leguminosae Extract Plants Isoflavones

Target:  

Apoptosis EGFR HSP ERK Akt

Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR L858R/T790M mutation, and fungal infections .
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2
Ipriflavone
Ipriflavone
0 Images
2 Cited Publications
Cat. No.: HY-N0094
CAS No.: 35212-22-7
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease Cancer

Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
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2
6''-O-Malonylgenistin
6''-O-Malonylgenistin
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2 Cited Publications
Cat. No.: HY-N0917
CAS No.: 51011-05-3
Synonyms: Malonylgenistin; Genistin malonate
Category:  

Flavonoids Glycine max (L.) merr Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

Drug Metabolite Taste Receptor

6''-O-Malonylgenistin (Malonylgenistin) is a glycosylated isoflavone and metabolite of Genistin (HY-N0595). 6''-O-Malonylgenistin activates hTAS2R39. 6''-O-Malonylgenistin can be used in the research of bitter taste .
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2
Daidzein (Standard)
Daidzein (Standard)
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2 Cited Publications
Cat. No.: HY-N0019R
CAS No.: 486-66-8
Category:  

Leguminosae Extract Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Glycine max (L.) merr Sunscreen Phenols Cosmetic Research Disease Research Fields Cancer

Target:  

Reference Standards PPAR Endogenous Metabolite

Daidzein (Standard) is the analytical standard of Daidzein. This product is intended for research and analytical applications. Daidzein is a soy isoflavone, which acts as a PPAR activator.
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