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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Kynurenic acid
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Kynurenic acid" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: Quinurenic acid
Category:
Alkaloids Human Gut Microbiota Metabolites Neurological Disease Quinoline Alkaloids Endogenous metabolite Disease Research Fields Endocrinology
Target:
11
Category:
Alkaloids Quinoline Alkaloids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
5
5 Cited Publications
Target:
Research Areas:
Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations .
4
4 Cited Publications
Cat. No.: HY-W040821
CAS No.: 454-29-5
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
Target:
2
2 Cited Publications
Synonyms: Quinurenic acid-d5
Cat. No.: HY-W014502
CAS No.: 13441-51-5
Cat. No.: HY-W010347S
CAS No.: 416845-90-4
Cat. No.: HY-100806R
CAS No.: 492-27-3
Synonyms: Quinurenic acid (Standard)
Cat. No.: HY-W014504
CAS No.: 343-65-7
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Synonyms: DM232
Target:
Research Areas:
Unifiram (DM232) is a AMPA receptor activator and cognitive enhancer. Unifiram activates the AMPA-mediated neurotransmission system. Unifiram reverses NBQX-induced amnesia in the passive avoidance test in mice. Unifiram reverses the antagonistic effect of kynurenic acid on NMDA-mediated [ 3H]NA release in rat hippocampal slices. Unifiram enhances excitatory synaptic transmission in the rat hippocampus in vitro. Unifiram can be used in studies related to amnesia and cognitive dysfunction, including age-related memory decline, neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease, multiple sclerosis, schizophrenia, and attention deficit hyperactivity disorder .
Target:
Cat. No.: HY-107512R
CAS No.: 2439-02-3
Cat. No.: HY-W014502R
CAS No.: 13441-51-5
Cat. No.: HY-100834R
CAS No.: 131123-76-7
Synonyms: 5,7-DCKA (Standard)
Target:
Research Areas:
5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid (HY-100834). This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycine’s role in NMDA receptor-mediated synaptic transmission .
Cat. No.: HY-12347R
CAS No.: 199666-03-0
Target:
Research Areas:
Ro 61-8048 (Standard) is the analytical standard of Ro 61-8048. This product is intended for research and analytical applications. Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations .
Cat. No.: HY-W014504S1
Cat. No.: HY-W014504R
CAS No.: 343-65-7
Cat. No.: HY-118720A
CAS No.: 1638758-72-1
Synonyms: U-23 TFA
Target:
Research Areas:
Ovothiol A TFA (U-23 TFA) is an antioxidant. Ovothiol A TFA can be isolated from the tissues of marine invertebrates, algae and fish. Ovothiol A acts synergistically with glutathione to actively scavenge ROS and free radicals, and quench the triplet state of Kynurenic acid (HY-100806), thereby inhibiting oxidative stress and photodamage. OSH is expected to serve as an excellent photoprotective agent to inhibit the harmful effects caused by solar ultraviolet radiation .
Cat. No.: HY-P702306
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GPR35; Kynurenic acid Receptor; G Protein-Coupled Receptor 35; KYNA Receptor; G-Protein Coupled Receptor 35
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-182456
CAS No.: 1426319-74-5
Target:
Research Areas:
CHDI-340246 is an orally active kynurenine monooxygenase (KMO) inhibitor. CHDI-340246 blocks KMO activity, alters the metabolic flux of the kynurenine pathway, inhibits the production of 3-hydroxykynurenine and quinolinic acid, elevates the levels of kynurenine and kynurenic acid, and restores electrophysiological abnormalities in transgenic mouse models of Huntington's disease. CHDI-340246 can be used in studies related to Huntington's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
