Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
TK
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "TK" in MCE Product Catalog:
14
Category:
Neurological Disease Plants Flavonoids Leguminosae Flavonones Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology
Target:
9
9 Cited Publications
Target:
Research Areas:
TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor . TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity .
3
Target:
3
3 Cited Publications
Synonyms: Hydroxythiamine chloride hydrochloride
Target:
2
Target:
Research Areas:
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an Kd value of 22 nM (Apo-TK, transketolase lacking bound thiamine) .
2
2 Cited Publications
Target:
Research Areas:
TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM .
1
1 Cited Publications
Cat. No.: HY-112889B
Target:
Research Areas:
Oxythiamin diphosphate ammonium is a potent transketolase (TK) inhibitor .
Cat. No.: HY-W008491
CAS No.: 22423-26-3
Target:
Research Areas:
TK-112690 is a UPP1 inhibitor. TK-112690 inhibits murine small intestinal uridine phosphorylase (UPase) with an IC50 of 12.5 μM and human small intestinal UPase with an IC50 of 20.0 μM in vitro. TK-112690 increases plasma uridine concentration in mice. TK-112690 can be used for the study of cancer and pulmonary fibrosis .
Cat. No.: HY-W342664
CAS No.: 55612-21-0
Synonyms: FIRU
Target:
Research Areas:
2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer .
Cat. No.: HY-112889
CAS No.: 10497-04-8
Target:
Research Areas:
Oxythiamin diphosphate is a potent transketolase (TK) inhibitor .
Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 inhibits tumor growth and enables decrease of cutaneous toxicity in mice .
Cat. No.: HY-17422S1
CAS No.: 1185179-33-2
Synonyms: Aciclovir-d4; Acycloguanosine-d4
Target:
Research Areas:
TK-129 is an orally active, low-toxicity, potent KDM5B inhibitor (with high affinity; IC50=44 nM). TK-129 exerts cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 reduces ang II-induced activation of cardiac fibroblasts in vitro and reduces isoprenaline-induced myocardial remodelling and fibrosis in vivo. TK-129 can be used in studies of cardiovascular disease .
Target:
Research Areas:
Transketolase-IN-3 is a potent transketolase (TK) inhibitor. Transketolase-IN-3 has herbicidal activity and has inhibitory effects against Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). Transketolase-IN-3 can be used for the research of herbicides .
Cat. No.: HY-114327
CAS No.: 14689-84-0
Synonyms: R15P
Category:
Cat. No.: HY-D2415
CAS No.: 2411845-57-1
Target:
Research Areas:
Transketolase-IN-1 is a transketolase inhibitor and a herbicide. Transketolase-IN-1 inhibits weed growth and exhibits safety for maize and wheat at specified application rates. Transketolase-IN-1 can be used for the research of weed control in wheat and maize fields .
Target:
Research Areas:
(+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor .
Cat. No.: HY-P1079
CAS No.: 158484-42-5
Target:
Research Areas:
Cat. No.: HY-E70075
Synonyms: GDH-TIM; GDH-TPI
Target:
Research Areas:
α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerol phosphate dehydrogenase (GDH) and triphosphate isomerase (TIM). α-Glycerophosphate Dehydrogenase-Triosephosphate can be used to determine the activity of transketolase (TK) in hemolytic substances of red blood cells to evaluate vitamin B deficiency .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
