107 Results for "

UTP

" in MedChemExpress (MCE) Product Catalog:
Products (107)

107 Results for "UTP" in MCE Product Catalog:

4
4 Cited Publications
Art. -Nr.: HY-W013093
CAS. Nr.: 19817-92-6
Synonyms: UTP trisodium salt; Uridine 5'-triphosphate trisodium salt
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .
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4
4 Cited Publications
Art. -Nr.: HY-107372A
CAS. Nr.: 116295-90-0
Reinheit:  ≥97.0%
Synonyms: UTP trisodium dihydrate; Uridine 5'-triphosphate trisodium dihydrate
Uridine triphosphate (trisodium dihydrate) (UTP (trisodium dihydrate); Uridine 5'-triphosphate (trisodium dihydrate)) is a biochemical reagent.
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3
3 Cited Publications
Art. -Nr.: HY-42682
CAS. Nr.: 1772-03-8
Synonyms: D-Galactosamine HCl
D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure .
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3
3 Cited Publications
Art. -Nr.: HY-125818
CAS. Nr.: 65-47-4
Reinheit:  ≥98.0%
Synonyms: Cytidine triphosphate; 5'-CTP
Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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3
3 Cited Publications
Art. -Nr.: HY-W013100
CAS. Nr.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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1
1 Cited Publications
Art. -Nr.: HY-112582C
CAS. Nr.: 3056945-59-3
Reinheit:  99.70%
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
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1
1 Cited Publications
Art. -Nr.: HY-153083
Target:  

mRNA SARS-CoV

Forschungsgebiete:  

Infection

COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) is an mRNA encoding the SARS-CoV-2 spike protein with enhanced performance via chemical modification. COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) replaces natural uridine (UTP) with N1-Me-Pseudo UTP, which effectively reduces immunogenicity and improves stability and translation efficiency. The 3' UTR of COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) optimizes AU-rich elements through HuR anchor sites, exhibiting higher translation efficiency. COVID-19 Spike Protein mRNA is widely used in COVID-19-related scientific research and vaccine development .
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1
1 Cited Publications
Art. -Nr.: HY-141567A
Reinheit:  ≥98.0%
Synonyms: Pseudo-UTP trisodium solution (100 mM)
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
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1
1 Cited Publications
Art. -Nr.: HY-155878A
CAS. Nr.: 1630828-71-5
Forschungsgebiete:  

Others

5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis .
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Art. -Nr.: HY-150145A
Reinheit:  99.26%
Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP .
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Art. -Nr.: HY-153079
Reinheit:  97.00%
Target:  

mRNA

Forschungsgebiete:  

Others

eGFP mRNA (N1-Me-Pseudo UTP) will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response.
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Art. -Nr.: HY-107372
CAS. Nr.: 63-39-8
Synonyms: UTP; Uridine 5'-triphosphate
Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
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Art. -Nr.: HY-157783
CAS. Nr.: 2377000-84-3
Reinheit:  99.04%
Target:  

DNA/RNA Synthesis

Forschungsgebiete:  

Cancer

Dencatistat is a CTP synthetase 1 (b) inhibitor. CTPS1 is a key rate-limiting enzyme that catalyzes the conversion of UTP to CTP. Dencatistat can be used for research on lymphoma .
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Art. -Nr.: HY-153080
Reinheit:  94.6%
Target:  

Fluorescent Dye mRNA

Forschungsgebiete:  

Others

Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a modified form of firefly luciferase mRNA, which is N1-methylated pseudo uridine (N1-Me-Pseudo UTP). Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a commonly used reporter molecule in biomedical and mRNA research and its core function is to rapidly and quantitatively monitor the expression and delivery efficiency of mRNA through the emission of light signals .
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Art. -Nr.: HY-D1669
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Art. -Nr.: HY-D1686
CAS. Nr.: 186033-13-6
Synonyms: Biotin-16-UTP tetralithium
Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .
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Art. -Nr.: HY-150145
Cy5-UTP is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be employed to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays that combine with Cy5-UTP .
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Art. -Nr.: HY-171493
Forschungsgebiete:  

Others

mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.
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Art. -Nr.: HY-107372H
CAS. Nr.: 19817-92-6
Synonyms: Uridine 5'-triphosphate trisodium salt, 100 mM Solution, PCR Grade
UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
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Art. -Nr.: HY-112581B
Reinheit:  99.89%
Synonyms: 5-Methoxy-UTP trisodium solution (100 mM); 5-OMe-UTP trisodium solution (100 mM)
5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
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