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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
123 Results for "
UTP
" in MedChemExpress (MCE) Product Catalog:
Products (123)
123 Results for "UTP" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-W013093
CAS No.: 19817-92-6
Synonyms: UTP trisodium salt; Uridine 5'-triphosphate trisodium salt
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
4
Category:
Vitaceae Extract Plant Microorganism Disease Research Fields Inflammation/Immunology Vitis vinifera cv. Zalema Extract Saccharides Monosaccharides
Target:
4
4 Cited Publications
Synonyms: UTP trisodium dihydrate; Uridine 5'-triphosphate trisodium dihydrate
3
3 Cited Publications
Cat. No.: HY-W013100
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Research Areas:
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
1
1 Cited Publications
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
Research Areas:
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium.
The product specifications provided below refer solely to the active content of N1-Methylpseudouridine-5′-triphosphate trisodium.
1
1 Cited Publications
Cat. No.: HY-153083
COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) is an mRNA encoding the SARS-CoV-2 spike protein with enhanced performance via chemical modification. COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) replaces natural uridine (UTP) with N1-Me-Pseudo UTP, which effectively reduces immunogenicity and improves stability and translation efficiency. The 3' UTR of COVID-19 Spike Protein mRNA (N1-Me-Pseudo UTP) optimizes AU-rich elements through HuR anchor sites, exhibiting higher translation efficiency. COVID-19 Spike Protein mRNA is widely used in COVID-19-related scientific research and vaccine development .
1
1 Cited Publications
Cat. No.: HY-141567A
Purity: ≥98.0%
Synonyms: Pseudo-UTP trisodium solution (100 mM)
Target:
Research Areas:
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
The product specifications provided below indicate the total amount only; they do not represent the actual content of Pseudouridine 5'-triphosphate trisodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of Pseudouridine 5'-triphosphate trisodium.
1
1 Cited Publications
Cat. No.: HY-155878A
CAS No.: 1630828-71-5
Research Areas:
5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis .
The product specifications provided below indicate the total amount only; they do not represent the actual content of 5-Fluoro-2′-deoxy-UTP.
The product specifications provided below indicate the total amount only; they do not represent the actual content of 5-Fluoro-2′-deoxy-UTP.
1
1 Cited Publications
Target:
Cyclopentenyl uracil is a non-cytotoxic Uridine-Cytidine Kinase inhibitor and an antagonist of EIDD-1931 (NHC) (HY-125033) bioactivation. Cyclopentenyl uracil blocks NHC phosphorylation by inhibiting UCK1/UCK2, reduces intracellular NHC-TP accumulation, and depletes UTP/CTP pools, thereby antagonizing the antiviral activity of NHC and inhibiting dengue virus replication. Cyclopentenyl uracil is used in research on SARS-CoV-2 infection, dengue virus infection, leukemia, and solid tumors .
1
Research Areas:
Dencatistat (STP938) is a selective and orally active CTPS1 inhibitor (IC50 = 9.3 nM) that reduces the rate-limiting conversion of UTP to CTP. Dencatistat exhibits more than 1300-fold selectivity for CTPS2. Dencatistat modulates BCL2 family transcripts and cell cycle pathways, and inhibits SARS-CoV-2 replication and interferon-induced Mx expression. Dencatistat has antiproliferative and tumor growth-inhibiting effects in mantle cell lymphoma models. Dencatistat inhibits clonogenic growth, migration, invasion, and xenograft tumor growth in lung adenocarcinoma, with tumor selectivity over normal bronchial epithelial cells. Dencatistat can be used for research on COVID-19, mantle cell lymphoma, essential thrombocythemia, and lung adenocarcinoma .
Cat. No.: HY-150145A
Purity: 99.26%
Research Areas:
Cy5-UTP sodium (10 mM in water) is a fluorescently labeled ribonucleotide triphosphate that can be used as a substrate for terminal deoxynucleotide transferase (TdT). Cy5-UTP sodium can be used to label RNA probes generated in vitro (Ex/Em: 650/665 nm). Cy5-UTP sodium can be applied in FISH, multi-color fluorescence analysis, especially in dual-color expression arrays combined with Cy5-UTP .
The product specifications provided below indicate the total amount only; they do not represent the actual content of Cy5-UTP sodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of Cy5-UTP sodium.
Cat. No.: HY-153079
Purity: 97.00%
eGFP mRNA (N1-Me-Pseudo UTP) will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response.
The product specifications provided below refer solely to the active content of eGFP mRNA (N1-Me-Pseudo UTP).
The product specifications provided below refer solely to the active content of eGFP mRNA (N1-Me-Pseudo UTP).
Cat. No.: HY-153080
Purity: 94.6%
Target:
Research Areas:
Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a modified form of firefly luciferase mRNA, which is N1-methylated pseudo uridine (N1-Me-Pseudo UTP). Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a commonly used reporter molecule in biomedical and mRNA research and its core function is to rapidly and quantitatively monitor the expression and delivery efficiency of mRNA through the emission of light signals .
Cat. No.: HY-D1669
Cat. No.: HY-D1686
CAS No.: 186033-13-6
Synonyms: Biotin-16-UTP tetralithium
Cat. No.: HY-150145
Cat. No.: HY-171493
Target:
Research Areas:
mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.
Cat. No.: HY-107372H
CAS No.: 19817-92-6
Synonyms: Uridine 5'-triphosphate trisodium salt, 100 mM Solution, PCR Grade
Research Areas:
UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
The product specifications provided below indicate the total amount only; they do not represent the actual content of UTP trisodium salt.
The product specifications provided below indicate the total amount only; they do not represent the actual content of UTP trisodium salt.
Cat. No.: HY-112581B
Purity: 99.89%
Synonyms: 5-Methoxy-UTP trisodium solution (100 mM); 5-OMe-UTP trisodium solution (100 mM)
Target:
Research Areas:
5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
The product specifications provided below refer solely to the active content of 5-Methoxyuridine 5'-triphosphate trisodium.
The product specifications provided below refer solely to the active content of 5-Methoxyuridine 5'-triphosphate trisodium.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
