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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
aromatase inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "aromatase inhibitors" in MCE Product Catalog:
21
21 Publications Verification
Synonyms: CGS 20267
Category:
Alkaloids Other Alkaloids Plants Compositae Extract Disease Research Fields Cancer Tephrosia purpurea (L.) Pers.
Target:
10
10 Cited Publications
Cat. No.: HY-N0292
CAS No.: 32619-42-4
Category:
Cardiovascular Disease Anti-aging Plants Canarium album (Lour.) Rauesch. Iridoids Terpenoids Burseraceae Extract Phenols Polyphenols Disease Research Fields Inflammation/Immunology Cancer
Target:
10
7
7 Cited Publications
Synonyms: FCE 24304; EXE
Target:
Research Areas:
Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .
4
Target:
Research Areas:
Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
3
Target:
Research Areas:
Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia .
3
3 Cited Publications
Synonyms: CGS 16949A; (Rac)-FAD286 hydrochloride
Target:
Research Areas:
Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
3
3 Cited Publications
Synonyms: CGS 16949A free base; (Rac)-FAD286
Target:
Research Areas:
Fadrozole (CGS 16949A free base) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
3
3 Cited Publications
Cat. No.: HY-14247B
CAS No.: 176702-70-8
Synonyms: CGS 16949A hemihydrate; (Rac)-FAD286 hydrochloride hemihydrate
Target:
Research Areas:
Fadrozole hydrochloride hemihydrate is an orally active, potent, selective and nonsteroidal aromatase inhibitor, with an IC50 of 6.4 nM. Fadrozole hydrochloride hemihydrate inhibits the production of estrogen and progesterone, with IC50 values of 0.03 and 120 μM. Fadrozole hydrochloride hemihydrate shows prevention of spontaneous tumours. Fadrozole hydrochloride hemihydrate can be used for the research of estrogen-dependent disease and cancer .
3
3 Cited Publications
Cat. No.: HY-N1993
CAS No.: 82517-12-2
Category:
Flavonoids Metabolic Disease Plants Other Families Extract Disease Research Fields Isoflavones
Target:
1
1 Cited Publications
Cat. No.: HY-18719E
CAS No.: 110025-28-0
Research Areas:
Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study .
1
1
Target:
Environmental Pollutants Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Fungal Androgen Receptor
Research Areas:
Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC50 of 1 μM .
1
1 Cited Publications
Cat. No.: HY-18719B
CAS No.: 1197194-41-4
Research Areas:
Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study .
Synonyms: (R)-Fadrozole; (R)-CGS 16949A free base; FAD286
Target:
Research Areas:
Dexfadrostat ((R)-Fadrozole) is an orally active and selective aromatase inhibitor, with human aromatase IC50 values of 6.4 nM. Dexfadrostat suppresses estrogen synthesis, reduces circulating estradiol levels and suppresses aldosterone production. Dexfadrostat can be used for the research of breast cancer, primary aldosteronism, and hypertension .
Cat. No.: HY-N8487
CAS No.: 22395-22-8
Category:
Flavonoids Neurological Disease Flavones Zornia brasiliensis Leguminosae Extract Plants Disease Research Fields Inflammation/Immunology
Target:
Category:
Flavonols Flavonoids Metabolic Disease Phenols Polyphenols Plants Other Families Extract Disease Research Fields
Target:
Cat. No.: HY-N5012
CAS No.: 84633-29-4
Synonyms: Pasakbumin A
Category:
Terpenoids Diterpenoids Plants Other Families Extract Disease Research Fields Endocrinology
Target:
Cat. No.: HY-N12326
CAS No.: 1350028-90-8
Target:
Research Areas:
Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
