22 Results for "

devd

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "devd" in MCE Product Catalog:

138
138 Publications Verification
Cat. No.: HY-12466
CAS No.: 210344-95-9
Purity:  ≥98.0%
Target:  

Caspase

Research Areas:  

Cancer

Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 μM .
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47
47 Cited Publications
Cat. No.: HY-P1001
CAS No.: 169332-60-9
Target:  

Caspase

Research Areas:  

Cancer

Ac-DEVD-CHO is a Caspase-3 inhibitor with a Ki value of 230 pM.
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13
13 Cited Publications
Cat. No.: HY-P1005
CAS No.: 201608-14-2
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
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5
5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
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3
3 Cited Publications
Cat. No.: HY-P0034
CAS No.: 285570-60-7
Synonyms: Caspase-3 Inhibitor III
Target:  

Caspase Apoptosis

Research Areas:  

Metabolic Disease

Ac-DEVD-CMK (Caspase-3 Inhibitor III) is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK significantly inhibits apoptosis induced by high levels of glucose or Ingenol 3,20-dibenzoate?(HY-137295). Ac-DEVD-CMK can be used in a variety of experimental approaches to inhibit apoptosis .
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3
3 Cited Publications
Cat. No.: HY-P0034A
Synonyms: Caspase-3 Inhibitor III TFA
Target:  

Caspase Apoptosis

Research Areas:  

Metabolic Disease

Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK TFA significantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate (IDB; HY-137295). Ac-DEVD-CMK TFA can be used in a variety of experimental approaches to inhibit apoptosis .
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1
1 Cited Publications
Cat. No.: HY-P1006
CAS No.: 189950-66-1
Target:  

Caspase

Research Areas:  

Others

Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases .
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1
1 Cited Publications
Cat. No.: HY-103349
CAS No.: 10129-56-3
Purity:  99.68%
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

PETCM is an activator of caspase-3 and acts as an cytochrome c (cyto c)-dependent manner. PETCM promotes Apaf-1 oligomerization and induces cell apoptosis in HeLa cells .
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Cat. No.: HY-P1986
CAS No.: 1135416-11-3
Target:  

Caspase

Research Areas:  

Cancer

Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
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Cat. No.: HY-D2365
CAS No.: 304014-13-9
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
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Cat. No.: HY-W796158
CAS No.: 250584-13-5
Target:  

Cathepsin

Research Areas:  

Inflammation/Immunology

Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro .
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Cat. No.: HY-D1432
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor .
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Cat. No.: HY-P3363
Target:  

Caspase

Research Areas:  

Cancer

Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
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Cat. No.: HY-P5830A
Research Areas:  

Others

Biotin-DEVD-CHO (TFA) is a biotin-conjugated form of the caspase-3 and -7 inhibitor – Ac-DEVD-CHO. Biotin-DEVD-CHO (TFA) can be used for affinity purification of the active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO (TFA) can detect the active caspase-3 in vitro .
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Cat. No.: HY-P5830
CAS No.: 178603-73-1
Target:  

Caspase

Research Areas:  

Others

Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .
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Cat. No.: HY-P4403
CAS No.: 223538-61-2
Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Research Areas:  

Others

Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
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Cat. No.: HY-P5936
CAS No.: 201608-15-3
Synonyms: devd-CHO-CPP 32
Target:  

Caspase

Research Areas:  

Cancer

Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) is a potent and reversible caspase-3 inhibitor .
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Cat. No.: HY-P6285
CAS No.: 1426396-40-8
Target:  

Fluorescent Dye Caspase

Research Areas:  

Cancer

Z-TPE-2DEVD is a specific probe for caspase-3 .
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Cat. No.: HY-P1001A
Target:  

Caspase Apoptosis

Research Areas:  

Neurological Disease Cancer

Ac-DEVD-CHO TFA is a peptide inhibitor of caspase-3 (Ki=230 pM) and caspase-7. Ac-DEVD-CHO TFA reduces caspase-3 activity and apoptosis induced by Prostaglandin E2 (HY-101952) in rat cortical neurons. Ac-DEVD-CHO TFA is promising for research of neurodegenerative diseases and cancers .
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Cat. No.: HY-P10162A
Target:  

Caspase

Research Areas:  

Others

Ac-DMQD-AMC TFA is a fluorogenic substrate for caspase-3 or caspase-10. Similar to Ac-DEVD-AMC, it releases the AMC (7-amino-4-methylcoumarin) fluorophore, resulting in fluorescence. Ac-DMQD-AMC TFA can be used to measure caspase activity in in vitro apoptosis monitoring .
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