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Results for "

ferulic acid

" in MedChemExpress (MCE) Product Catalog:

標的別:	Apoptosis (3) Autophagy (2) Bcl-2 Family (3) Biochemical Assay Reagents (1) COX (1) Drug Derivative (2) Drug Metabolite (3) Endogenous Metabolite (13) Environmental Pollutants (1) Ferroptosis (3) FGFR (5) Fungal (1) Isotope-Labeled Compounds (2) JAK (1) nAChR (1) NF-κB (1) p38 MAPK (2) Parasite (2) Phosphatase (1) Reactive Oxygen Species (ROS) (4) Reference Standards (7) ROCK (1) STAT (1) β-catenin (3)
研究分野別:	Cancer (14) Cardiovascular Disease (4) Infection (6) Inflammation/Immunology (4) Metabolic Disease (4) Neurological Disease (7)

標的別:

Apoptosis (3)

Autophagy (2)

Bcl-2 Family (3)

Biochemical Assay Reagents (1)

COX (1)

Drug Derivative (2)

Drug Metabolite (3)

Endogenous Metabolite (13)

Environmental Pollutants (1)

Ferroptosis (3)

FGFR (5)

Fungal (1)

Isotope-Labeled Compounds (2)

JAK (1)

nAChR (1)

NF-κB (1)

p38 MAPK (2)

Parasite (2)

Phosphatase (1)

Reactive Oxygen Species (ROS) (4)

Reference Standards (7)

ROCK (1)

STAT (1)

β-catenin (3)

研究分野別:

Cancer (14)

Cardiovascular Disease (4)

Infection (6)

Inflammation/Immunology (4)

Metabolic Disease (4)

Neurological Disease (7)

阻害剤およびアゴニスト

生化学アッセイ試薬

天然物

同位体標識化合物

製品番号	製品名	Target	研究分野	構造式

HY-N0060

Ferulic acid Maximum Cited Publications 16 Publications Verification Coniferic acid	FGFR Endogenous Metabolite	Infection Neurological Disease Cancer
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W018643

Ferulic acid methyl ester 1 Publications Verification Methyl ferulate	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology Cancer
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-N0060B

*(E)-Ferulic* acid** 1 Publications Verification (E)-Coniferic acid	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-P2875

Hemicellulase	Endogenous Metabolite	Others
Hemicellulase is a hemicellulose-targeting hydrolase that breaks down the binding of glucose and polymers to water molecules present in plant fibers. Hemicellulase specifically degrades hemicellulose (such as xylan and mannan) in plant cell walls by hydrolyzing β-1,4-xylosidic bonds and ester bonds (such as acetyl and ferulic acid ester bonds). Hemicellulase relies on the synergistic action of the glycoside hydrolase (GH) and carbohydrate esterase (CE) families to achieve efficient hydrolysis through acid-base catalysis (such as Glu/Asp residues) and substrate binding pockets. Hemicellulase can be used in the food industry (such as improving bread texture)， biofuel production (lignocellulose pretreatment) and paper industry (biobleaching) .

HY-N0060A

Ferulic acid sodium Maximum Cited Publications 16 Publications Verification Coniferic acid sodium	FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W005288

4-Vinylphenol (10% in Propylene glycol) 1 Publications Verification 4-Hydroxystyrene	Apoptosis Endogenous Metabolite	Cancer
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0061

Ethyl ferulate 3 Publications Verification	Reactive Oxygen Species (ROS)	Neurological Disease
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-N7715

Ferulic acid acyl-β-D-glucoside ferulic acid glucoside; Feruloyl glucose ester	Drug Metabolite	Others
Ferulic acid acyl-β-D-glucoside (Ferulic acid glucoside) is a metabolite of Ferulic Acid (HY-N0060). Ferulic acid acyl-β-D-glucoside can be isolated from flaxseed extract. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀ values of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-N0060R

Ferulic acid (Standard) 1 Publications Verification Coniferic acid (Standard)	Reference Standards FGFR Endogenous Metabolite	Cancer
Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-147323

Ferulic acid 4-O-sulfate ferulic acid 4-sulfate	Drug Metabolite	Cardiovascular Disease
Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol ferulic acid ester	Drug Derivative Apoptosis Reactive Oxygen Species (ROS) JAK STAT	Inflammation/Immunology Cancer
Cycloartenyl ferulate (Cycloartenol ferulate; Cycloartenol ferulic acid ester) is a derivative of γ-oryzanol (HY-B2194) with multiple biological activities including antioxidant, anti-inflammatory, and anti-tumor properties. Cycloartenyl ferulate selectively binds to IFNγR1 (binding affinity K_d = 0.5 μM) to activate the canonical JAK1/2-STAT1 signaling pathway. Cycloartenyl ferulate inhibits paraquat (PQ)-triggered apoptosis and ROS in HK2 cells. Cycloartenyl ferulate enhances the activation and cytolytic activity of natural killer (NK) cells by upregulating the expression of NK cell activation receptors (NKG2D, NKp30, NKp44) and the release of cytotoxic molecules and cytokine IFNγ. Cycloartenyl ferulate exerts anti-cancer effects in tumor mice models. Cycloartenyl ferulate can be used for the study of cancer and allergic inflammation intervention .

HY-W250112

Lignin alkali	Environmental Pollutants Biochemical Assay Reagents	Others
Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

HY-N0060BS

*(E)-Ferulic* acid-d3** (E)-Coniferic acid-d₃	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299 .

HY-N11516

*Erythro-guaiacylglycerol-β-ferulic* acid ether**	Others	Others
Erythro-guaiacylglycerol-β-ferulic acid ether is a natural product that can be isolated from Gueldenstaedtia verna .

HY-W005288S

4-Vinylphenol-d4 4-Hydroxystyrene-d₄	Apoptosis Endogenous Metabolite Isotope-Labeled Compounds	Cancer
4-Vinylphenol-d₄ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-W009993

3,4-Methylenedioxycinnamic acid	Parasite	Infection Metabolic Disease
3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a K_i of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the K_m value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

HY-W051164

5-Hydroxyvanillin	Endogenous Metabolite	Infection
5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-W018643A

*(E)-Ferulic* acid methyl ester** Methyl (E)-ferulate	COX	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N3894

Ferulamide	nAChR	Neurological Disease
Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .

HY-N0060BR

*(E)-Ferulic* acid (Standard)** (E)-Coniferic acid (Standard)	Reference Standards β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid (Standard) is the analytical standard of (E)-Ferulic acid. This product is intended for research and analytical applications. (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N0060S1

Ferulic acid-13C3	Isotope-Labeled Compounds FGFR Endogenous Metabolite	Cancer
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-147323R

Ferulic acid 4-O-sulfate (Standard) ferulic acid 4-sulfate (Standard)	Reference Standards Drug Metabolite	Cardiovascular Disease
Ferulic acid 4-O-sulfate (Standard) is the analytical standard of Ferulic acid 4-O-sulfate. This product is intended for research and analytical applications. Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice[1].

HY-139715

IMD-ferulic	NF-κB	Cancer
IMD-ferulic is a covalently linked NF-κB modulator that improves the adjuvanticity of small molecule immune potentiators.

HY-N15724

Cimicifugic acid E 2-E-Feruloylpiscidic acid	Others	Others
Cimicifugic acid E (2-E-Feruloylpiscidic acid) is a ferulic acid ester compound found in the rhizomes of Cimicifuga racemosa. Cimicifugic acid E is promising for research of menopausal syndrome .

HY-N11441

*cis-Ferulic* acid 4-O-β-D-glucopyranoside**	Phosphatase	Metabolic Disease
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-145294

ROCK2-IN-5	ROCK	Neurological Disease
ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation .

HY-N7715A

*(E)-Ferulic* acid acyl-β-D-glucoside** (E)-ferulic acid glucoside; (E)-Feruloyl glucose ester	Others	Others
(E)-Ferulic acid acyl-β-D-glucoside ((E)-Ferulic acid glucoside) (compoun 4C) is an acyl-β-D-glucoside that can be isolated from Riesling Wine. (E)-Ferulic acid acyl-β-D-glucoside exhibits antioxidant activity .

HY-N0060AR

Ferulic acid sodium (Standard) Coniferic acid sodium (Standard)	Reference Standards FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)	Cardiovascular Disease Cancer
10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

HY-W018643R

Ferulic acid methyl ester (Standard) Methyl ferulate (Standard)	p38 MAPK Reference Standards Autophagy	Neurological Disease Inflammation/Immunology Cancer
Ferulic acid methyl ester (Standard) is the analytical standard of Ferulic acid methyl ester (HY-W018643). This product is intended for research and analytical applications. Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-W051164R

5-Hydroxyvanillin (Standard)	Endogenous Metabolite Reference Standards	Infection
5-Hydroxyvanillin (Standard) is the analytical standard of 5-Hydroxyvanillin (HY-W051164). This product is intended for research and analytical applications. 5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-W709715

*Dihydro ferulic* acid 4-O-β-D-glucuronide**	Drug Derivative	Others
Dihydro ferulic acid 4-O-β-D-glucuronide is a natural product that can be found in asafoetida.

HY-N16424

Methyl (Z)-ferulate Me cis-ferulate; cis-ferulic acid methyl ester	Fungal	Infection
Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS ⁺ radical .

HY-N18768

Leontopodium alpinum extract	Others	Metabolic Disease
Leontopodium Alpinum Extract is a fully water-soluble botanical cosmetic raw material, obtained from the Asteraceae plant Edelweiss. Its main component is ferulic acid, which is an organic acid with strong skin care activity.

HY-W009993R

3,4-Methylenedioxycinnamic acid (Standard)	Parasite Reference Standards	Infection Metabolic Disease
3,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

製品番号	製品名	Type

HY-W250112

Lignin alkali	生化学アッセイ試薬
Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

Lignin alkali

生化学アッセイ試薬

Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

製品番号	製品名	Category	Target	構造式

HY-N0060

Ferulic acid Maximum Cited Publications 16 Publications Verification Coniferic acid	Structural Classification Classification of Application Fields Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols other families Simple Phenylpropanols Sunscreen Phenols Phenylpropanoids Cosmetic Research Disease Research Fields Source Classification Cancer	FGFR Endogenous Metabolite
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W018643

Ferulic acid methyl ester 1 Publications Verification Methyl ferulate	Monophenols Classification of Application Fields Neurological Disease Simple Phenylpropanols Stemonaceae Phenols Phenylpropanoids Plants Disease Research Fields Stemona tuberosa Lour. Cancer Source Classification	p38 MAPK Autophagy
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-N0060B

*(E)-Ferulic* acid** 1 Publications Verification (E)-Coniferic acid	Classification of Application Fields Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Microorganisms other families Simple Phenylpropanols Phenols Phenylpropanoids Disease Research Fields Source Classification Cancer	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N0060A

Ferulic acid sodium Maximum Cited Publications 16 Publications Verification Coniferic acid sodium	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Disease Research Fields Source Classification Cancer	FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W005288

4-Vinylphenol (10% in Propylene glycol) 1 Publications Verification 4-Hydroxystyrene	Monophenols Microorganisms Classification of Application Fields Rubiaceae Phenols Plants Endogenous metabolite Disease Research Fields Hedyotis diffusa Willd. Source Classification Cancer	Apoptosis Endogenous Metabolite
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0061

Ethyl ferulate 3 Publications Verification	Monophenols Simple Phenylpropanols Phenols Dicerothamnus rhinocerotis Phenylpropanoids Umbelliferae Plants Source Classification	Reactive Oxygen Species (ROS)
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-N7715

Ferulic acid acyl-β-D-glucoside ferulic acid glucoside; Feruloyl glucose ester	Structural Classification Monophenols Classification of Application Fields Simple Phenylpropanols Rosaceae Other Diseases Phenols Phenylpropanoids Plants Aruncus sylvester Kostel. Disease Research Fields Source Classification	Drug Metabolite
Ferulic acid acyl-β-D-glucoside (Ferulic acid glucoside) is a metabolite of Ferulic Acid (HY-N0060). Ferulic acid acyl-β-D-glucoside can be isolated from flaxseed extract. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀ values of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-N0060R

Ferulic acid (Standard) 1 Publications Verification Coniferic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols other families Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Source Classification	Reference Standards FGFR Endogenous Metabolite
Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol ferulic acid ester	Triterpenes Monophenols other families Classification of Application Fields Terpenoids Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Drug Derivative Apoptosis Reactive Oxygen Species (ROS) JAK STAT
Cycloartenyl ferulate (Cycloartenol ferulate; Cycloartenol ferulic acid ester) is a derivative of γ-oryzanol (HY-B2194) with multiple biological activities including antioxidant, anti-inflammatory, and anti-tumor properties. Cycloartenyl ferulate selectively binds to IFNγR1 (binding affinity K_d = 0.5 μM) to activate the canonical JAK1/2-STAT1 signaling pathway. Cycloartenyl ferulate inhibits paraquat (PQ)-triggered apoptosis and ROS in HK2 cells. Cycloartenyl ferulate enhances the activation and cytolytic activity of natural killer (NK) cells by upregulating the expression of NK cell activation receptors (NKG2D, NKp30, NKp44) and the release of cytotoxic molecules and cytokine IFNγ. Cycloartenyl ferulate exerts anti-cancer effects in tumor mice models. Cycloartenyl ferulate can be used for the study of cancer and allergic inflammation intervention .

HY-N11516

*Erythro-guaiacylglycerol-β-ferulic* acid ether**	Other Terpenoids Leguminosae Terpenoids Plants Source Classification Gueldenstaedtia verna (Georgi) Boriss.	Others
Erythro-guaiacylglycerol-β-ferulic acid ether is a natural product that can be isolated from Gueldenstaedtia verna .

HY-W009993

3,4-Methylenedioxycinnamic acid	Ketones, Aldehydes, Acids Piperaceae Plants Piper nigrum Linn. Source Classification	Parasite
3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a K_i of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the K_m value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

HY-W051164

5-Hydroxyvanillin	Infection Classification of Application Fields Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-W018643A

*(E)-Ferulic* acid methyl ester** Methyl (E)-ferulate	Structural Classification Monophenols Ginkgoaceae Classification of Application Fields Simple Phenylpropanols Other Diseases Phenols Phenylpropanoids Plants Ginkgo biloba Disease Research Fields Source Classification	COX
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N3894

Ferulamide	Alkaloids Monophenols Phenols Plants Umbelliferae Source Classification Carphephorus corymbosus (Nutt.) Torr. & A.Gray	nAChR
Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .

HY-N0060BR

*(E)-Ferulic* acid (Standard)** (E)-Coniferic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms other families Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Source Classification	Reference Standards β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite
(E)-Ferulic acid (Standard) is the analytical standard of (E)-Ferulic acid. This product is intended for research and analytical applications. (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N15724

Cimicifugic acid E 2-E-Feruloylpiscidic acid	Ranunculaceae Phenols Polyphenols Plants Cimicifuga racemosa (L.) Nutt. Source Classification	Others
Cimicifugic acid E (2-E-Feruloylpiscidic acid) is a ferulic acid ester compound found in the rhizomes of Cimicifuga racemosa. Cimicifugic acid E is promising for research of menopausal syndrome .

HY-N11441

*cis-Ferulic* acid 4-O-β-D-glucopyranoside**	Ketones, Aldehydes, Acids Zygophyllaceae Plants Nitraria sibirica Pall Source Classification	Phosphatase
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-N7715A

*(E)-Ferulic* acid acyl-β-D-glucoside** (E)-ferulic acid glucoside; (E)-Feruloyl glucose ester	Structural Classification Monophenols Asteraceae Phenols Plants Source Classification	Others
(E)-Ferulic acid acyl-β-D-glucoside ((E)-Ferulic acid glucoside) (compoun 4C) is an acyl-β-D-glucoside that can be isolated from Riesling Wine. (E)-Ferulic acid acyl-β-D-glucoside exhibits antioxidant activity .

HY-N0060AR

Ferulic acid sodium (Standard) Coniferic acid sodium (Standard)	Structural Classification Monophenols other families Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Source Classification	Reference Standards FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)
10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

HY-W018643R

Ferulic acid methyl ester (Standard) Methyl ferulate (Standard)	Structural Classification Monophenols Simple Phenylpropanols Stemonaceae Phenols Phenylpropanoids Plants Stemona tuberosa Lour. Source Classification	p38 MAPK Reference Standards Autophagy
Ferulic acid methyl ester (Standard) is the analytical standard of Ferulic acid methyl ester (HY-W018643). This product is intended for research and analytical applications. Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-W051164R

5-Hydroxyvanillin (Standard)	Structural Classification Phenols Polyphenols Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
5-Hydroxyvanillin (Standard) is the analytical standard of 5-Hydroxyvanillin (HY-W051164). This product is intended for research and analytical applications. 5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-W709715

*Dihydro ferulic* acid 4-O-β-D-glucuronide**	Structural Classification Cactaceae Other Phenylpropanoids Phenylpropanoids Opuntia ficus-indica (L.) Mill. Plants Source Classification	Drug Derivative
Dihydro ferulic acid 4-O-β-D-glucuronide is a natural product that can be found in asafoetida.

HY-N16424

Methyl (Z)-ferulate Me cis-ferulate; cis-ferulic acid methyl ester	Monophenols Phenols Aizoaceae Plants Tetragonia tetragonioides (Pall.) Kuntze Source Classification	Fungal
Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS ⁺ radical .

HY-N18768

Leontopodium alpinum extract	Structural Classification Extract	Others
Leontopodium Alpinum Extract is a fully water-soluble botanical cosmetic raw material, obtained from the Asteraceae plant Edelweiss. Its main component is ferulic acid, which is an organic acid with strong skin care activity.

HY-W009993R

3,4-Methylenedioxycinnamic acid (Standard)	Ketones, Aldehydes, Acids Piperaceae Plants Piper nigrum Linn. Source Classification	Parasite Reference Standards
3,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

製品番号	製品名	構造式

HY-N0060BS

(E)-Ferulic acid-d3

(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299 .

HY-W005288S

4-Vinylphenol-d4
4-Vinylphenol-d₄ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0060S1

Ferulic acid-13C3
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

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