Search Result

Results for "

fiber

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenylate Cyclase (2) Adrenergic Receptor (2) Akt (4) Amino Acid Derivatives (1) AMPK (3) Amylases (1) Amyloid-β (8) Antibiotic (2) Apoptosis (11) Arp2/3 Complex (1) Arrestin (2) Autophagy (8) Bacterial (18) Biochemical Assay Reagents (31) Calcium Channel (2) Caspase (1) Cathepsin (1) Cdc42-binding kinase (1) Ceramidase (1) Chloride Channel (1) Cholinesterase (ChE) (2) COX (8) Cytochrome P450 (1) DAGL (1) Dihydrofolate reductase (DHFR) (2) Dopamine Receptor (2) Drug Derivative (5) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (11) Environmental Pollutants (11) ERK (3) Fluorescent Dye (68) Fungal (3) Gap Junction Protein (1) Glycosidase (1) GPR55 (1) GSK-3 (1) HSV (8) IFNAR (1) IGF-1R (1) iGluR (2) Interleukin Related (4) Isotope-Labeled Compounds (12) Kinesin (1) mAChR (2) MDM-2/p53 (1) Microtubule/Tubulin (2) Mitosis (1) Monoamine Oxidase (1) mTOR (6) Myosin (1) Neurotensin Receptor (2) NF-κB (13) NO Synthase (9) Nuclear Factor of activated T Cells (NFAT) (1) OGT (1) Parasite (1) PARP (1) Phosphodiesterase (PDE) (2) PI3K (1) Potassium Channel (4) PPAR (8) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (14) ROCK (9) SARS-CoV (1) Sodium Channel (6) Somatostatin Receptor (2) TGF-beta/Smad (4) TGF-β Receptor (1) TNF Receptor (1) Transthyretin (TTR) (1) TRP Channel (2) α-synuclein (8)
By Research Areas:	Cancer (30) Cardiovascular Disease (14) Infection (22) Inflammation/Immunology (25) Metabolic Disease (15) Neurological Disease (49)
Oligonucleotides:	Thickeners (1) Emulsifiers (1) Phospholipids (1) Antisense Oligonucleotides (1)

204

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0338

Ethylene glycol,98%	Environmental Pollutants	Others
Ethylene glycol is an organic compound that is often used as an antifreeze agent and coolant. Ethylene glycol lowers the freezing point by forming hydrogen bonds with water molecules, exerting antifreeze activity. Ethylene glycol is also used as a raw material in the synthesis of polymers such as polyester fibers and polyurethanes .

HY-16690

BTS 3 Publications Verification N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine	Myosin	Others
BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC₅₀s of ~5 µM for actin- and Ca ²⁺-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers .

HY-122266

Orcein	Biochemical Assay Reagents	Metabolic Disease
Orcein is an irreversible stain that specifically targets elastic fibers and can interact hydrophobically with the protein components in elastic fibers. Orcein makes elastic fibers in tissues appear purple or purple-red. Orcein can be used for morphological studies of Drosophila polytene chromosomes and for qualitative and quantitative analysis of elastic fibers, collagen fibers and other components in atherosclerotic plaques .

HY-N0335

Indigo 1 Publications Verification	Fluorescent Dye	Others
Indigo is a blue dye. Indigo stains cellulose fibers such as cotton. Indigo stains food or biological samples to visualize and quantify the uptake or distribution of substances by organisms .

HY-P99588

Stamulumab 1 Publications Verification MYO-029	TGF-β Receptor	Metabolic Disease
Stamulumab (MYO-029) is a recombinant human IgG1λ antibody that binds to myostatin and neutralizes its activity by preventing binding to its endogenous high-affinity receptor ActRIIB. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia in SCID mice. Stamulumab has the potential for Becker muscular dystrophy (BMD), facioscapulohumeral dystrophy (FSHD), and limb-girdle muscular dystrophy (LGMD) research .

HY-158183

NMD670	Chloride Channel	Neurological Disease
NMD670 is an orally active inhibitor of skeletal muscle specific chloride channel ClC-1 with an EC₅₀ of 1.6 μM. NMD670 enhances neuromuscular transmission and improves muscle contraction and strength. NMD670 can be used in the study of muscle weakness and muscle fatigue .

HY-125221

DJ4	ROCK Cdc42-binding kinase	Cancer
DJ4 is a ATP-competitive inhibitor of ROCK1/2 (IC₅₀ values:5 and 50 nM) and MRCKα/β (IC₅₀ values:10 and 100 nM). DJ4 blocks stress fiber formation and inhibits migration and invasion of cancer cells. DJ4 can be used for study of lung cancer, breast cancer, and pancreatic (PANC-1) cancer .

HY-D0363

Pigment Red 166	Fluorescent Dye
Pigment Red 166 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-W144037

Valeramide Pentanimidic acid	Biochemical Assay Reagents	Others
Valeramide (Pentanimidic acid) is an important raw material for organic synthesis, which is produced by ammonolysis of Caproamide. Valeramide can be used to make polyamides, amide resins, preservatives and nylon fibers .

HY-119747

WAY-123223	Potassium Channel	Cardiovascular Disease
WAY-123223 is an orally active potassium channel (Potassium Channel) blocker. WAY-123223 prolongs the transmembrane action potential duration and cardiac refractory period of canine Purkinje fibers. In canine models, WAY-123223 increases the ventricular fibrillation threshold, restores sinus rhythm from ventricular fibrillation, and exerts antiarrhythmic effects. WAY-123223 can be used in research related to cardiovascular diseases such as arrhythmias .

HY-W440408

Poly(oxyethyleneoxyterephthaloyl) Polyester short-cut fiber	Environmental Pollutants Biochemical Assay Reagents	Others
Poly(oxyethyleneoxyterephthaloyl) is a commonly used waterproof polymer material. Poly(oxyethyleneoxyterephthaloyl) can be used in textile, electrical and other fields .

HY-150187

20:4 Lyso PI	GPR55 ERK ROCK Calcium Channel	Neurological Disease
20:4 Lyso PI acts as an activator of GPR55 and RhoA. 20:4 Lyso PI activates the GPR55-RhoA-ROCK pathway, thereby inducing morphological changes, cytoskeleton assembly, cell rounding and stress fiber formation. 20:4 Lyso PI can be used in research related to diseases such as those of the nervous system .

HY-D0278

Pigment red 170	Environmental Pollutants Fluorescent Dye	Others
Pigment Red 170 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-N9412

4-O-Methyl-D-glucuronic acid	Others	Others
4-O-Methyl-D-glucuronic acid is a kind of hemicellulose that can be isolated from the holocellulose of the Ganpi bast fibers .

HY-N15841

C25 Ceramide (d18:1/25:0)	Ceramidase	Others
C25 Ceramide (d18:1/25:0) is an endogenous ultra-long-chain ceramide that antagonizes the detrimental effects of long-chain ceramides on insulin sensitivity. C25 Ceramide (d18:1/25:0) is specifically enriched in oxidative skeletal muscle fibers, where it serves dual roles in providing structural support to cell membranes and regulating cellular signaling. By participating in the regulation of lipid homeostasis within muscle fibers, C25 Ceramide (d18:1/25:0) helps maintain normal insulin signaling. C25 Ceramide (d18:1/25:0) is primarily utilized in research concerning metabolic diseases—particularly in mechanistic studies investigating the muscle fiber type-specific aspects of insulin resistance .

HY-D0332

Disperse Orange 1	Fluorescent Dye
Disperse Orange 1 is an orange-orange dye commonly used for fiber dyeing.

HY-D0565

Disperse blue 291G	Fluorescent Dye
Disperse blue 291G is a blue dye commonly used for fiber dyeing.

HY-Y0383

Dimethyl terephthalate	Biochemical Assay Reagents	Others
Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-D0280

Pigment red 57-1	Fluorescent Dye
Pigment red 57-1 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-W742955

Pargeverine hydrochloride	mAChR	Neurological Disease
Pargeverine hydrochloride is an antispasmodic opioid alkaloid. Pargeverine hydrochloride has a moderate and non-selective blockade of muscarinic cholinergic fibers. Pargeverine hydrochloride can be used in the research of painful spasms .

HY-N10373

Caffeoyl alcohol	Others	Others
Caffeoyl alcohol is a monomer constituting Catechyl lignin. Catechyl lignin is a linear homopolymer of caffeyl alcohol, a natural source of carbon fiber and high-value chemicals .

HY-100945

Nitrocaramiphen hydrochloride	mAChR	Neurological Disease
Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (K_i: 5.5 nM). Nitrocaramiphen Hydrochloride inhibits the hyperpolarizing effect of muscarine in the muscle fibers .

HY-D1219

Disperse blue 359	Fluorescent Dye
Disperse blue 359 is a blue dye commonly used for fiber dyeing.

HY-106718

Barucainide	Sodium Channel	Cardiovascular Disease
Barucainide is an Ib-class anti-arrhythmic agent (moderately blocking sodium channel). Barucainide exhibits concentration-dependent inhibitory effects on the maximum upstroke velocity (V_max) of Purkinje fibers and ventricular muscle in dogs. Barucainide significantly shortens the action potential duration (APD). Barucainide significantly inhibits the pacemaker activity frequency of atrial tissue in rabbits and the enhanced automaticity of Purkinje fibers under normal resting potential in response to isoproterenol. Barucainide cannot inhibit the abnormal automaticity emission frequency of canine Purkinje fibers induced by barium. Barucainide can be used for research on arrhythmias .

HY-W587729

Ethylene terephthalate cyclic dimer	Drug Intermediate	Others
Ethylene terephthalate cyclic dimer is a intermediate of polyethylene terephthalate (PET). PET is a common plastic used in fibers and packaging materials.

HY-D0632

Pigment Red 147	Fluorescent Dye
Pigment Red 147 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0384

Pigment Red 144	Fluorescent Dye
Pigment Red 144 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0345

Pigment Red 178	Fluorescent Dye
Pigment Red 178 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-N1982

Denudatine	Others	Cardiovascular Disease
Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium . Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine .

HY-P3618

Cortistatin-29 (reduced)	Somatostatin Receptor	Neurological Disease Inflammation/Immunology
Cortistatin-29 is a neuropeptide. Cortistatin-29 alleviates neuropathic pain. Cortistatin-29 binds all somatostatin (SS) receptor subtypes with high affinity and shows IC₅₀ values of 2.8 nM, 7.1 nM, 0.2 nM, 3.0 nM, 13.7 nM for SSTR1, SSTR2, SSTR3, SSTR4, SSTR5, respectively. Cortistatin-29 shows anti-fibrotic effects .

HY-W592622

Polyacrylonitrile (MW 250000)	Biochemical Assay Reagents	Others
Polyacrylonitrile is a fiber. Polyacrylonitrile is widely used as a material for the preparation of ultrafiltration membranes, hemodialysis membranes, textiles, flame retardants and carbon fibers. Polyacrylonitrile (MW 250000) can be electrospun .

HY-Y0338R

Ethylene glycol (Standard)	Reference Standards Biochemical Assay Reagents	Others
Ethylene glycol (Standard) is the analytical standard of Ethylene glycol. This product is intended for research and analytical applications. Ethylene glycolis an organic compound of which formula is (CH2OH)2. Ethylene glycolcan be used as a raw material to produce polyester fibers or for antifreeze use .

HY-P10675

Peptide K	Biochemical Assay Reagents	Metabolic Disease
Peptide K is a self-assembling peptide fiber that can be used to prepare fibrous nanocomposite hydrogels. The fibrous nanocomposite hydrogels have a dynamic network that adapts to cells and enhances cell-matrix and cell-cell interactions, thus significantly promoting the mechanotransduction, metabolic energy, and osteogenesis of encapsulated stem cells .

HY-D0667

Disperse yellow 211	Fluorescent Dye
Disperse yellow 211 is a yellow dye commonly used for fiber dyeing.

HY-D0575

Disperse violet 93	Fluorescent Dye
Disperse violet 93 is a violet dye commonly used for fiber dyeing.

HY-D0637

Disperse Blue 106	Fluorescent Dye
Disperse Blue 106 is a yellow dye commonly used for fiber dyeing.

HY-D0610

Disperse Violet 33	Fluorescent Dye
Disperse Violet 33 is a violet dye commonly used for fiber dyeing.

HY-D0524

Disperse black 9	Fluorescent Dye
Disperse black 9 is a violet dye commonly used for fiber dyeing.

HY-D0521

Disperse orange 29	Fluorescent Dye
Disperse orange 29 is an orange-orange dye commonly used for fiber dyeing.

HY-D0382

Disperse Orange 30	Fluorescent Dye
Disperse Orange 30 is an orange-orange dye commonly used for fiber dyeing.

HY-D0491

C.I. Disperse blue 79	Fluorescent Dye
C.I. Disperse blue 79 is a blue dye commonly used for fiber dyeing.

HY-D0400

C.I. Disperse yellow 23	Fluorescent Dye
C.I. Disperse yellow 23 is a yellow dye commonly used for fiber dyeing.

HY-P10712

Nap-GFFY	Biochemical Assay Reagents	Others
Nap-GFFY, a naphthylacetic acid modifi ed tetrapeptide of GFFY, is a self-assembling fiber peptide .

HY-D0497

C.I. Disperse orange 37	Fluorescent Dye
C.I. Disperse orange 37 is an orange-orange dye commonly used for fiber dyeing.

HY-D1064

Pigment red 57	Fluorescent Dye
Pigment red 57 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0383

Pigment Red 146	Fluorescent Dye
Pigment Red 146 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0568

Pigment red 242	Fluorescent Dye
Pigment Red 242 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D1139

Pigment red 177	Fluorescent Dye
Pigment Red 177 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0549

Pigment red 266	Fluorescent Dye
Pigment Red 266 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

HY-D0596

Pigment Red 188	Fluorescent Dye
Pigment Red 188 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P1645

Papain 10+ Cited Publications	Carica papaya L. Structural Classification Natural Products Classification of Application Fields Caricaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	Cathepsin
Papain is a cysteine protease of the peptidase C1 family. Papain enhances red cell agglutination by anti-D and anti-A, and increases red cell sensitivity to K cell-mediated lysis in ADCC assays. Papain can induce pulmonary emphysema. Papain can be used for the researches of Rh haemolytic disease of the newborn and pulmonary emphysema .

HY-16563

Narciclasine Maximum Cited Publications 22 Publications Verification Lycoricidinol	Alkaloids Classification of Application Fields Narcissus tazetta Linn. var. chinensis M.Roemer Plants Isoquinoline Alkaloids Amaryllidaceae Disease Research Fields Source Classification Cancer Agricultural Research	ROCK
Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.

HY-N0335

Indigo 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Leguminosae Indigofera tinctoria Linn. Plants Disease Research Fields Cancer	Fluorescent Dye
Indigo is a blue dye. Indigo stains cellulose fibers such as cotton. Indigo stains food or biological samples to visualize and quantify the uptake or distribution of substances by organisms .

HY-B1513

α-Cyclodextrin 2 Publications Verification	Structural Classification Zea mays L. Polysaccharides Classification of Application Fields Gramineae Other Diseases Plants Disease Research Fields Saccharides Source Classification	Environmental Pollutants SARS-CoV Microtubule/Tubulin
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids .

HY-N0168A

(Rac)-Hesperetin	Structural Classification Flavonoids other families Flavonones Phenols Polyphenols Plants Source Classification	TGF-beta/Smad NF-κB
(Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .

HY-W010041

Scyllo-Inositol	Natural Products Endogenous metabolite Source Classification	α-synuclein Amyloid-β
Scyllo-Inositol is an inhibitor that targets the aggregation of misfolded proteins (such as α-synuclein and Amyloid-β), is orally effective, and can cross the blood-brain barrier. Scyllo-Inositol can selectively bind to and stabilize non-toxic oligomers, preventing them from converting into toxic fibers, exerting protein homeostasis regulation and neuroprotective activity. Scyllo-Inositol binds to the hydrophobic region of pathogenic proteins, inhibits protein aggregation, and promotes lysosome- and proteasome-mediated degradation pathways, thereby reducing neurotoxicity. Scyllo-Inositol can be used in the study of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease .

HY-122958

Peucedanocoumarin III	Structural Classification Carpesium cernuum L. Coumarins Phenylpropanoids Umbelliferae Plants Source Classification	α-synuclein
Peucedanocoumarin III is an α-synuclein fiber depolymerizer with blood-brain barrier permeability. Peucedanocoumarin III depolymerizes β-sheet aggregate structures, promotes aggregate clearance, inhibits β23-induced cytotoxicity, blocks the formation of Lewy body-like inclusions, and prevents dopaminergic neuron loss. Peucedanocoumarin III can be used in studies related to Parkinson's disease .

HY-P2031

Phallacidin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Arp2/3 Complex
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

HY-N3677

Dammarenediol II	Triterpenes Structural Classification other families Boswellia freerana Terpenoids Plants Source Classification	OGT Akt mTOR GSK-3 Reactive Oxygen Species (ROS) Apoptosis PARP MDM-2/p53
Dammarenediol II is a ginsenoside precursor . Dammarenediol II reduces the activity of O-GlcNAc transferase (OGT) and downregulates the global O-GlcNAcylation level. Dammarenediol II inhibits the phosphorylation of Akt, mTOR and GSK3β. Dammarenediol II inhibits human carboxylesterase activity, VEGF-induced ROS production, stress fiber formation and vascular endothelial cadherin disruption. Dammarenediol II promotes cell apoptosis (apoptosis), increases the levels of cleaved PARP1 and p53, and inhibits retinal microvascular leakage. Dammarenediol II can be used in studies related to liver cancer and diabetic retinopathy .

HY-N1677

2,6-Dimethoxy-1,4-benzoquinone	Infection Quinones other families Classification of Application Fields Metabolic Disease Benzene Quinones Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Akt mTOR Bacterial Fungal AMPK
2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H₂O₂ generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .

HY-N2438

Methylophiopogonanone B 2 Publications Verification	Ophiopogon japonicus (L. f.) Ker-Gawl. Structural Classification Flavonoids Liliaceae Classification of Application Fields Other Diseases Phenols Polyphenols Plants Other Flavonoids Disease Research Fields Source Classification	Ras Microtubule/Tubulin
Methylophiopogonanone B is a homoisoflavonoid compound. Methylophiopogonanone B can be isolated from O. japonicus root. Methylophiopogonanone B promotes Rho activation and Tubulin depolymerization. Methylophiopogonanone B significantly increases GTP-Rho, but not GTP-Rac or GTP-CDC42. Methylophiopogonanone B induces cell morphological change via melanocyte dendrite retraction and stress fiber formation. Methylophiopogonanone B exhibits strong antioxidant activity. Methylophiopogonanone B can be used in the research of cervical cancer .

HY-N9412

4-O-Methyl-D-glucuronic acid	Ketones, Aldehydes, Acids Thymelaeaceae Plants Wikstroemia sikokiana Franch. & Sav. Source Classification	Others
4-O-Methyl-D-glucuronic acid is a kind of hemicellulose that can be isolated from the holocellulose of the Ganpi bast fibers .

HY-N15841

C25 Ceramide (d18:1/25:0)	Structural Classification Lipid	Ceramidase
C25 Ceramide (d18:1/25:0) is an endogenous ultra-long-chain ceramide that antagonizes the detrimental effects of long-chain ceramides on insulin sensitivity. C25 Ceramide (d18:1/25:0) is specifically enriched in oxidative skeletal muscle fibers, where it serves dual roles in providing structural support to cell membranes and regulating cellular signaling. By participating in the regulation of lipid homeostasis within muscle fibers, C25 Ceramide (d18:1/25:0) helps maintain normal insulin signaling. C25 Ceramide (d18:1/25:0) is primarily utilized in research concerning metabolic diseases—particularly in mechanistic studies investigating the muscle fiber type-specific aspects of insulin resistance .

HY-N10341

Centaureidin	Flavonoids Flavones Tanacetum microphyllum DC. Plants Compositae Source Classification	IFNAR ROCK
Centaureidin is an orally active IFN-promoter that can be isolated from Bidens pilosa with an EC₅₀ of 0.9 μg/mL. Centaureidin activates the Rho signal pathway, leading to actin and tubulin disassembly, and resulting in dendrite retraction and stress fiber formation in melanocytes. Centaureidin shows high tumor cell growth inhibitory activities. Centaureidin significantly inhibits paw edema in mice ^{[1][2][3][4][5]}.

HY-N10373

Caffeoyl alcohol	Leguminosae Phenols Polyphenols Plants Source Classification Medicago sativa L.	Others
Caffeoyl alcohol is a monomer constituting Catechyl lignin. Catechyl lignin is a linear homopolymer of caffeyl alcohol, a natural source of carbon fiber and high-value chemicals .

HY-N1982

Denudatine	Cardiovascular Disease Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Others
Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium . Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine .

HY-16563R

Narciclasine (Standard) Lycoricidinol (Standard)	Structural Classification Alkaloids Narcissus tazetta Linn. var. chinensis M.Roemer Plants Isoquinoline Alkaloids Amaryllidaceae Source Classification	Reference Standards ROCK
Narciclasine (Standard) is the analytical standard of Narciclasine. This product is intended for research and analytical applications. Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.

HY-N6875

Oleuropeinic acid	other families Iridoids Canarium album (Lour.) Rauesch. Classification of Application Fields Terpenoids Phenols Polyphenols Metabolic Disease Plants Burseraceae Disease Research Fields Source Classification	Others
oleuropeinic acid is present initially in olive tissues or formed by the thermal treatment, possibly by the oxidation of oleuropein. Oleuropeinic acid is an antioxidant-soluble fiber .

HY-N11909

8-O-4,8-O-4-Dehydrotriferulic acid	Zea mays L. Ketones, Aldehydes, Acids Gramineae Plants Source Classification	Others
8-O-4,8-O-4-Dehydrotriferulic acid is a dehydrotriferulic acid that can be isolated from saponified corn bran insoluble fiber .

HY-N4309A

Lotusine hydroxide	Cardiovascular Disease Alkaloids Classification of Application Fields Phenols Polyphenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Nymphaeaceae Disease Research Fields Source Classification	Amylases Glycosidase
Lotusine hydroxide is an orally active signaling pathway modulator and enzyme inhibitor, with an IC₅₀ of 30.60 μg/mL against α-amylase and an IC₅₀ of 36.15 μg/mL against α-glucosidase. Lotusine hydroxide inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine hydroxide induces apoptosis, triggers G₀/G₁ cell cycle arrest and inhibits cancer cell proliferation. Lotusine hydroxide reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine hydroxide is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder .

HY-W010041R

Scyllo-Inositol (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards α-synuclein Amyloid-β
Scyllo-Inositol is an inhibitor that targets the aggregation of misfolded proteins (such as α-synuclein and Amyloid-β), is orally effective, and can cross the blood-brain barrier. Scyllo-Inositol can selectively bind to and stabilize non-toxic oligomers, preventing them from converting into toxic fibers, exerting protein homeostasis regulation and neuroprotective activity. Scyllo-Inositol binds to the hydrophobic region of pathogenic proteins, inhibits protein aggregation, and promotes lysosome- and proteasome-mediated degradation pathways, thereby reducing neurotoxicity. Scyllo-Inositol can be used in the study of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease .

HY-N16431

NFAT-133	Natural Products Microorganisms Source Classification	AMPK Nuclear Factor of activated T Cells (NFAT) Interleukin Related Endogenous Metabolite
NFAT-133 is an aromatic polyketide with immunosuppressive and antidiabetic activity. NFAT-133 activates the AMPK pathway, promoting glucose uptake in L6 muscle fibers, thereby resisting diabetes. NFAT-133 inhibits the transcriptional activity of activated T-cell nuclear factor (NFAT), thereby suppressing the expression of IL-2 and the proliferation of T cells, demonstrating an immunosuppressive effect. NFAT-133 does not exhibit antibacterial activity or cytotoxicity, but it can weaken the production of NO in RAW264.7 cells induced by Lipopolysaccharide (LPS) (HY-D1056) .

HY-N0168AR

(Rac)-Hesperetin (Standard)	Structural Classification Flavonoids other families Flavonones Phenols Polyphenols Plants Source Classification	Reference Standards NF-κB TGF-beta/Smad
(Rac)-Hesperetin (Standard) is the analytical standard of (Rac)-Hesperetin. This product is intended for research and analytical applications. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .

HY-N1677R

2,6-Dimethoxy-1,4-benzoquinone (Standard)	Quinones other families Benzene Quinones Plants Endogenous metabolite Source Classification	Reference Standards Akt mTOR Bacterial Fungal AMPK
2,6-Dimethoxy-1,4-benzoquinone (Standard) is the analytical standard of 2,6-Dimethoxy-1,4-benzoquinone (HY-N1677). This product is intended for research and analytical applications. 2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness.

HY-N13170

Glycoside H2	Structural Classification Asclepiadaceae Plants Periploca sepium Bunge Steroids Source Classification	Others
Glycoside H2 is a potentiator of NGF-mediated nerve fiber outgrowth .

HY-N18779

Phoenix dactylifera extract	Structural Classification Extract	Bacterial
Phoenix dactylifera extract is rich in dietary fiber, phenols, tocopherols, carotenoids, and flavonoids, among other bioactive compounds, offering significant health and beauty benefits. It also possesses antioxidant, anti-inflammatory, antibacterial, and antiviral properties.

HY-N16477

Ciceritol	Structural Classification Leguminosae Cicer arietinum L. Plants Saccharides Monosaccharides Source Classification	Drug Metabolite
Ciceritol is a dietary fiber component/prebiotic targeting α-galactosidic linkage oligosaccharides. Ciceritol selectively promotes proliferation of beneficial bacteria like Bifidobacteria. Ciceritol is promising for research of gut microbiota-related diseases (e.g., irritable bowel syndrome, metabolic syndrome) .

HY-N18279

Bulbocapnine	Structural Classification Alkaloids Corydalis yanhusuo W. T. Wang Quinoline Alkaloids Plants Papaveraceae Source Classification	Dopamine Receptor Adrenergic Receptor
Bulbocapnine is an aporphine isoquinoline alkaloid that exerts antagonistic effects on dopamine Receptor) and α-adrenergic receptors, as well as anti-peroxidative effects. The K_i value of bulbocapnine for tyrosine hydroxylase (TH) is 0.20 mM. Bulbocapnine reduces intracellular dopamine content, inhibits TH activity, and decreases Ca ²⁺ concentration. Bulbocapnine antagonizes the dose-dependent inhibitory effect of dopamine on the heart rate acceleration induced by stimulating the postganglionic fibers of the right cardiac accelerator nerve .

Cat. No.	Product Name	Chemical Structure

HY-B1773AS3

Sodium propionate-13C3

Sodium propionate- ¹³C-3 is the ¹³C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .

HY-B1773AS4

Sodium propionate-d5

Sodium propionate-d₅ is the deuterium labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .

HY-B1773AS

Sodium propionate-13C

Sodium propionate- ¹³C is the ¹³C labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .

HY-W780208

Propanoic acid-13C3

Propanoic acid- ¹³C₃ is the ¹³C-labeled Propanoic acid (HY-W020017). Propanoic acid is an orally active short-chain fatty acid. Propanoic acid can be produced by intestinal bacteria from the metabolism of dietary fiber. Propanoic acid increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Propanoic acid also induces Apoptosis and Autophagy. Propanoic acid reduces HSV-1-induced keratitis. Propanoic acid has anticancer effects against glioblastoma. Propanoic acid exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Propanoic acid can be used in the research of spinal cord injury and Alzheimer's disease .

HY-B1773AS5

Sodium propionate-d3

Sodium propionate-d₃ is the deuterium labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .

HY-N0168AS1

(Rac)-Hesperetin-13C,d3

(Rac)-Hesperetin- ¹³C,d₃ is the ¹³C- and deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .

HY-Y0383S2

Dimethyl terephthalate-13C2-1
Dimethyl terephthalate- ¹³C₂-1 is ¹³C labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-B1773AS1

Sodium propionate-13C-1

Sodium propionate- ¹³C-1 is the ¹³C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .

HY-W750212

Acid Orange 7-13C6

Acid Orange 7- ¹³C₆ (Orange II- ¹³C₆) is the ¹³C-labeled Acid orange 7 (HY-N1442). Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-W707693

Scyllo-Inositol-d6

Scyllo-Inositol-d₆ is the deuterium labeled Scyllo-Inositol (HY-W010041). Scyllo-Inositol is an inhibitor that targets the aggregation of misfolded proteins (such as α-synuclein and Amyloid-β), is orally effective, and can cross the blood-brain barrier. Scyllo-Inositol can selectively bind to and stabilize non-toxic oligomers, preventing them from converting into toxic fibers, exerting protein homeostasis regulation and neuroprotective activity. Scyllo-Inositol binds to the hydrophobic region of pathogenic proteins, inhibits protein aggregation, and promotes lysosome- and proteasome-mediated degradation pathways, thereby reducing neurotoxicity. Scyllo-Inositol can be used in the study of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease .

HY-N0168AS

(Rac)-Hesperetin-d3

(Rac)-Hesperetin-d₃ is the deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin (HY-N0168), an orally active multi-target inhibitor. (Rac)-Hesperetin exhibits significant anti-tumor and anti-inflammatory activities by blocking the TGF-β1-mediated Fyn/RhoA signaling axis and the TLR4-MyD88-NF-κB inflammatory pathway. (Rac)-Hesperetin inhibits the formation of actin stress fibers and the migration and invasion of cancer cells, and is suitable for triple-negative breast cancer research. In inflammation models, (Rac)-Hesperetin effectively alleviates lung injury by reducing the release of pro-inflammatory mediators and regulating the activity of oxidative stress enzymes, and is suitable for acute lung injury research. (Rac)-Hesperetin also interferes with the entry and early replication processes of channel catfish virus, inhibits viral gene expression and progeny virus production, thereby protecting cells from virus-induced cytopathic effects .

HY-Y0383S

Dimethyl terephthalate-d4
Dimethyl terephthalate-d₄ is the deuterium labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks