61 Results for "

frog

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "frog" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P3443
Synonyms: PNA
Peanut agglutinin (PNA) is a carbohydrate-recognition protein that binds competitively and irreversibly to cell-surface β-D-Gal (1-3)-GalNAc, and this binding can be inhibited by D-galactose and asialofetuin. Peanut agglutinin recognizes exposed glycoepitopes and reflects the glycosylation status of cells. Peanut agglutinin can label glycoconjugates at neuromuscular junctions to safely visualize synaptic structures. Peanut agglutinin can be used to synthesize dyes to distinguish between normal and tumor tissues. Peanut agglutinin provides support for research on leukemia, Burkitt's tumors, and cutaneous squamous lesions .
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1
1 Cited Publications
Cat. No.: HY-B1243
CAS No.: 550-83-4
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Propoxycaine hydrochloride is a voltage-gated sodium channel inhibitor. Propoxycaine hydrochloride delays monophasic A spike action potential recovery. Propoxycaine hydrochloride increases bulk lateral, rotational, and annular lipid fluidity in neuronal membrane lipid bilayers, with greater inner monolayer fluidization, and induces membrane protein clustering. Propoxycaine hydrochloride can be used for the research of pain .
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Cat. No.: HY-P0270
CAS No.: 108433-95-0
Synonyms: Magainin II
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .
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Cat. No.: HY-P0263
CAS No.: 136212-91-4
Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
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Cat. No.: HY-P1629
CAS No.: 188713-69-1
Research Areas:  

Infection

Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .
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Cat. No.: HY-Y1097
CAS No.: 4376-18-5
Synonyms: 2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats .
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Cat. No.: HY-45509
CAS No.: 1208070-53-4
Synonyms: RAD150
Target:  

Androgen Receptor

Research Areas:  

Neurological Disease

TLB 150 Benzoate (RAD150) is a nonsteroidal androgen receptor modulator with an IC50 value of 0.13 μM. TLB 150 Benzoate spontaneously cyclizes under physiological conditions to form RAD 179, resulting in a persistent, reversible, and slow neuronal conduction blockade. TLB 150 Benzoate can be used for research on neurological diseases .
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Cat. No.: HY-P3915
CAS No.: 1350828-38-4
Target:  

Bacterial

Research Areas:  

Infection

Esculentin 1A is a frog skin-derived antimicrobial peptide (AMP) with potent in vitro anti-Pseudomonas activity .
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Cat. No.: HY-W276164
CAS No.: 1120-04-3
Synonyms: Sodium stearyl sulfate
Sodium octadecyl sulfate (Sodium stearyl sulfate) is a long-chain alkyl sodium sulfate that functions as an emulsifier, crosslinking agent, and regulator. Sodium octadecyl sulfate has high safety, with a LD50 greater than 3.00 Gm./Kg for both intraperitoneal injection in mice and oral administration in rats. Sodium octadecyl sulfate enhances continuous contraction of the gastrocnemius muscle in frogs and boosts intestinal smooth muscle activity in albino rats. However, Sodium octadecyl sulfate exerts no significant effect on isolated tortoise myocardium and does not alter the conduction function of frog sciatic nerves. Sodium octadecyl sulfate can also be used to coat the surface of starch aggregates, promote crosslinking and increase aggregate size through hydrophobic and electrostatic interactions, and further form a coexistent B-V type crystalline structure with acid-hydrolyzed gelatinized starch, thereby effectively modifying the structure and surface properties of high-starch systems .
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Cat. No.: HY-P2948
CAS No.: 9026-43-1
Synonyms: Ser/Thr protein kinase
Research Areas:  

Infection

Protein serine/threonine kinase (Ser/Thr protein kinase) is a signal transduction molecule. Protein serine/threonine kinase phosphorylates specific residues on target substrates, regulates phosphorylation-dependent signal cascades, modulates cellular processes of mycobacteria, blocks phagosome-lysosome fusion, promotes meiotic maturation of Xenopus laevis (African clawed frog) oocytes, rescues the phenotype of Saccharomyces cerevisiae (budding yeast) CDC5 mutants, and exhibits cell cycle phase-specific kinase activity. Protein serine/threonine kinase maintains a tightly regulated cell cycle expression pattern, and sustains the growth and survival of mycobacteria. Protein serine/threonine kinase can be used in studies related to tuberculosis .
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Cat. No.: HY-P0274
CAS No.: 102068-15-5
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

PGLa, a 21-residue peptide, is an antimicrobial peptide. PGLa is a member of the magainin family of antibiotic peptides found in frog skin and its secretions .
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Cat. No.: HY-P5594
CAS No.: 136033-70-0
Target:  

Fungal

Research Areas:  

Infection

Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi .
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Cat. No.: HY-P3762
CAS No.: 309245-16-7
Target:  

Endothelin Receptor

ANP (1-30), frog is a peptide fragment of atrial natriuretic peptide derived from frog. ANP (1-30), frog has natriuretic, diuretic, and vasorelaxant effects.
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Cat. No.: HY-W127668
CAS No.: 5957-17-5
Triethylcholine iodide is a choline acetyltransferase inhibitor and a regulator of the acetylcholine synthesis pathway. Triethylcholine iodide inhibits acetylcholine synthesis in brain tissues and blocks neuromuscular and autonomic ganglionic transmission. Triethylcholine iodide exerts weak curare-like effects at extremely high concentrations. Triethylcholine iodide elevates the pentylenetetrazol seizure threshold, alters electroencephalogram patterns in Felis catus, but does not affect the maximal electroshock seizure threshold in Oryctolagus cuniculus. Triethylcholine iodide can be used in seizure-related research .
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Cat. No.: HY-137172
CAS No.: 61595-77-5
Target:  

Sodium Channel

Research Areas:  

Others

ETH 157 is a neutral sodium-selective carrier. ETH 157 exhibits sufficient Na +/K + selectivity and enhanced Na +/Ca 2+ selectivity, making it suitable for the detection of extracellular Na + activity .
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Cat. No.: HY-P10265
CAS No.: 134709-16-3
Target:  

Melanocortin Receptor

Research Areas:  

Others

Melanostatin, frog is an inhibitor for α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM .
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Cat. No.: HY-P3645
CAS No.: 64887-70-3
Target:  

Melanocortin Receptor

Research Areas:  

Others

(Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment .
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Cat. No.: HY-W440982A
CAS No.: 6753-56-6
Synonyms: (Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine
Category:  

Animals Lipids

Target:  

Liposome

(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods .
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Cat. No.: HY-P4816
CAS No.: 388602-02-6
Target:  

Bacterial Fungal

Research Areas:  

Infection Inflammation/Immunology

Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .
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Cat. No.: HY-P2706
CAS No.: 64704-41-2
Target:  

Histamine Receptor

Research Areas:  

Endocrinology

Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine .
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