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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
human promyelocytic leukemia cells
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "human promyelocytic leukemia cells" in MCE Product Catalog:
17
17 Publications Verification
Cat. No.: HY-N6733
CAS No.: 38966-21-1
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1 Cited Publications
Cat. No.: HY-33350
CAS No.: 92953-10-1
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Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Antiarrhythmic agent .
Cat. No.: HY-W075517
CAS No.: 59061-53-9
Synonyms: 2-Methylimidazole zinc salt
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ZIF-8 (2-Methylimidazole zinc salt) is a caspase-1/Gasdermin D activator and a pH- and stimulus-responsive inducer of drug release, which serves as a highly efficient drug delivery carrier. ZIF-8 is a metal-organic framework (MOF). ZIF-8 activates the caspase-1/Gasdermin D-dependent pyroptosis pathway, induces pyroptosis, necrosis and immunogenic cell death, initiates in situ anti-tumor immunity, reprograms the immunosuppressive tumor microenvironment and inhibits tumor proliferation. ZIF-8 is applicable to related research on multiple cancers including colorectal cancer and breast cancer .
Synonyms: Decaethylene glycol monododecyl ether (C12E10); Polidocanol (10)
Cat. No.: HY-118563
CAS No.: 135784-48-4
Cat. No.: HY-173178
CAS No.: 925419-55-2
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LNS8801 is an orally active GPER activator with tumor suppressor activity. LNS8801 mediates suppression of cancer via GPER activation, with activity dependent on GPER expression. LNS8801 suppresses cancer growth in preclinical models. LNS8801 can be used for the research of cancer (including melanoma, pancreatic ductal adenocarcinoma, non-small cell lung cancer, leukemias, colon carcinomas) .
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6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer .
Cat. No.: HY-N6861
CAS No.: 95311-95-8
Cat. No.: HY-N15387
CAS No.: 1094030-09-7
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Cat. No.: HY-W024604
CAS No.: 22748-16-9
Synonyms: 4,4-Dimethylcyclopent-2-enone
Category:
Apocynaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Apocyniveneti Folium Cancer
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Cat. No.: HY-111008A
CAS No.: 95933-75-8
Synonyms: VF-233 hydrochloride
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Trimidox hydrochloride (VF-233) is a ribonucleotide reductase inhibitor with antileukemic activities. Trimidox hydrochloride inhibits the growth of human promyelocytic leukemia HL-60 cells with an IC50 of 35 μM .
Cat. No.: HY-N11546
CAS No.: 30994-75-3
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Cat. No.: HY-N6733R
CAS No.: 38966-21-1
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Cat. No.: HY-N17612
CAS No.: 366477-44-3
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Cat. No.: HY-W074006
CAS No.: 4023-53-4
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Tris (2-cyanoethyl) phosphine is a protein crosslinker. Tris (2-cyanoethyl) phosphine can be used to synthesize copper (I) complexes with anti-tumor activity .
Cat. No.: HY-N14495
CAS No.: 185853-14-9
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Cat. No.: HY-111008
CAS No.: 95933-74-7
Synonyms: VF-233
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Research Areas:
Trimidox (VF-233) is a ribonucleotide reductase inhibitor with antileukemic activities. Trimidox inhibits the growth of human promyelocytic leukemia HL-60 cells with an IC50 of 35 μM .
Cat. No.: HY-B2106DR
CAS No.: 9002-92-0
Synonyms: Decaethylene glycol monododecyl ether (C12E10) (Standard); Polidocanol (10) (Standard)
Cat. No.: HY-182550
CAS No.: 2763081-61-2
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Research Areas:
Indoluidin D is a selective dihydroorotate dehydrogenase (DHODH) inhibitor with a human DHODH IC50 of 210 nM. Indoluidin D selectively inhibits human DHODH activity, with induced effects rescuable by orotic acid. Indoluidin D promotes myeloid differentiation and inhibits cancer cell proliferation. Indoluidin D can be used for the research of acute promyelocytic leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
