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macrophylla

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

16

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0901
    Corynoxine
    3 Publications Verification

    		 Autophagy Neurological Disease Cancer
    Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
    Corynoxine
  • HY-W044525
    Phyllodulcin

    		Phosphodiesterase (PDE) Metabolic Disease Inflammation/Immunology
    Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling .
    Phyllodulcin
  • HY-W747297
    β-Selinene

    		COX Endogenous Metabolite Neurological Disease Inflammation/Immunology
    β-Selinene is a sesquiterpene and is the main active component of the essential oil of red purple hibiscus (Callicarpa macrophylla). β-Selinene exhibits significant related antioxidant activity, anti-inflammatory activity, and antipyretic analgesic activity. β-Selinene may exert antioxidant effects by directly scavenging free radicals (DPPH, NO, •OH) and chelating pro-oxidative metal ions (Fe²⁺); inhibit cyclooxygenase (COX) activity, reduce prostaglandin (such as PGE₂) synthesis to exert anti-inflammatory effects; regulate the thermoregulatory set point of the hypothalamus and inhibit inflammatory mediators to exert antipyretic and analgesic effects .
    β-Selinene
  • HY-W010409
    2-Octanone

    n-Hexyl methyl ketone

    		 Environmental Pollutants Others
    2-Octanone (n-Hexyl methyl ketone) is a Flavonoids product that can be isolated from the herbs of Hydrangea macrophylla .
    2-Octanone
  • HY-N12338
    (+)-Licarin

    		Insulin Receptor PI3K Akt Insecticide Mitochondrial Metabolism PPAR Others
    (+)-Licarin (Compound 7) is a compound derived from Ocotea macrophylla Kunth. leaves octanoid neolignans .
    (+)-Licarin
  • HY-N0901B
    Corynoxine hydrochloride

    		Autophagy Neurological Disease Cancer
    Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
    Corynoxine hydrochloride
  • HY-N3374
    Lochnerine

    10-O-Methylsarpagine

    		 Others Others
    Lochnerine is an indole alkaloid can be isolated from the stem bark extract of Alstonia macrophylla .
    Lochnerine
  • HY-N1272
    Secaubryenol

    		Endogenous Metabolite Others
    Secaubryenol is a class of 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla. Secaubryenol does not display any cytotoxic effect at a dose of 10 μg/mL .
    Secaubryenol
  • HY-N9892
    Guttiferone G

    		Sirtuin Others
    Guttiferone G inhibits recombinant human SIRT1 and SIRT2 (IC50: 9 and 22 μM, respectively). Guttiferone G is weakly cytotoxic in A2780 human ovarian cell line (IC50: 8.0 μg/mL). Guttiferone G can be isolated from Garcinia macrophylla .
    Guttiferone G
  • HY-N3860
    Erythrocentauric acid

    		Others Others
    Erythrocentauric acid is a Coumarins product that can be isolated from the roots of Gentiana macrophylla. .
    Erythrocentauric acid
  • HY-N9733
    2-Methoxyanofinic acid

    		Others Others
    2-Methoxyanofinic acid is an iridoid compound that can be found in Gentiana macrophylla .
    2-Methoxyanofinic acid
  • HY-N8868
    Hemiphroside B nonaacetate

    		Others Others
    Hemiphroside B nonaacetate is a Phenols product that can be isolated from the herbs of Hydrangea macrophylla .
    Hemiphroside B nonaacetate
  • HY-N2701
    6α-Hydroxynidorellol

    		Others Others
    6α-Hydroxynidorellol is a Diterpenoids product that can be isolated from the herbs of Callicarpa macrophylla .
    6α-Hydroxynidorellol
  • HY-N0962A
    (3S)-Hydrangenol 8-O-glucoside pentaacetate

    		Others Others
    (3S)-Hydrangenol 8-O-glucoside pentaacetate is a Flavonoids product that can be isolated from the herbs of Hydrangea macrophylla .
    (3S)-Hydrangenol 8-O-glucoside pentaacetate
  • HY-N0962
    (3R)-Hydrangenol 8-O-glucoside pentaacetate

    		Others Others
    (3R)-Hydrangenol 8-O-glucoside pentaacetate is a Flavonoids product that can be isolated from the herbs of Hydrangea macrophylla .
    (3R)-Hydrangenol 8-O-glucoside pentaacetate
  • HY-W010409R
    2-Octanone (Standard)

    n-Hexyl methyl ketone (Standard)

    		 Others Reference Standards Others
    2-Octanone (n-Hexyl methyl ketone) (Standard) is the analytical standard of 2-Octanone (HY-W010409). This product is intended for research and analytical applications. 2-Octanone is a Flavonoids product that can be isolated from the herbs of Hydrangea macrophylla .
    2-Octanone (Standard)
  • HY-N17773
    Hydrangeic acid

    		PPAR GLUT TNF Receptor Metabolic Disease
    Hydrangeic acid is an orally effective stilbene-type glycolipid metabolism regulator that lowers blood glucose and lipids. It can be isolated from processed leaves of Hydrangea macrophylla var. thunbergii. Hydrangeic acid is associated with glycolipid metabolism and insulin sensitivity regulation. Hydrangeic acid does not directly activate PPARγ or PPARα, but instead upregulates the mRNA expression of adiponectin, PPARγ2, GLUT4, and fatty acid-binding protein aP2, and downregulates TNF-α mRNA expression, promoting adipogenesis, glucose uptake, and GLUT4 translocation in 3T3-L1 cells. Simultaneously, Hydrangeic acid inhibits inflammatory factor-induced NO production, exerting activity in improving insulin resistance. Hydrangeic acid can be used in research related to type 2 diabetes and does not cause liver weight gain as a side effect.
    Hydrangeic acid

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