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Cat. No.: HY-N12338

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(+)-Licarin

(+)-Licarin (Compound 7) is a compound derived from Ocotea macrophylla Kunth. leaves octanoid neolignans.

For research use only. We do not sell to patients.

CAS No.: 42016-15-9
Formula: C₂₀H₂₀O₄
Molecular Weight:324.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(+)-Licarin Chemical Structure

CAS No.: 42016-15-9

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

(+)-Licarin (Compound 7) is a compound derived from Ocotea macrophylla Kunth. leaves octanoid neolignans^[1].

All Akt Isoforms :

All PPAR Isoforms :

All PI3K Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Platelet	IC₅₀	290 μM Compound: 16	Antiplatelet activity in rabbit platelets assessed as inhibition of arachidonic acid-induced platelet aggregation Antiplatelet activity in rabbit platelets assessed as inhibition of arachidonic acid-induced platelet aggregation	[PMID: 19880317]
Platelet	IC₅₀	488 μM Compound: 16	Antiplatelet activity in rabbit platelets assessed as inhibition of platelet activating factor-induced platelet aggregation Antiplatelet activity in rabbit platelets assessed as inhibition of platelet activating factor-induced platelet aggregation	[PMID: 19880317]
Platelet	IC₅₀	50.6 μM Compound: 23	Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of ADP-induced platelet aggregation preincubated for 2 mins before challenge measured after 2 mins by spectrophotometry Antiplatelet activity against New Zealand white rabbit platelets assessed as inhibition of ADP-induced platelet aggregation preincubated for 2 mins before challenge measured after 2 mins by spectrophotometry	[PMID: 24387347]
Platelet	IC₅₀	54.6 μM Compound: 16	Antiplatelet activity in rabbit platelets assessed as inhibition of adenosin 5'-diphosphate-induced platelet aggregation Antiplatelet activity in rabbit platelets assessed as inhibition of adenosin 5'-diphosphate-induced platelet aggregation	[PMID: 19880317]

Chemical Information

CAS No. 42016-15-9
Molecular Weight 324.37
Formula C₂₀H₂₀O₄
SMILES

COC1=C2C([C@@H]([C@@H](C3=CC=C(OCO4)C4=C3)O2)C)=CC(/C=C/C)=C1
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Coy-Barrera ED, et al. PAF-antagonistic bicyclo[3.2.1]octanoid neolignans from leaves of Ocotea macrophylla Kunth. (Lauraceae). Phytochemistry. 2009 Jul;70(10):1309-14. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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(+)-Licarin

High-Throughput Bioactive Compound Library

All Akt Isoforms

All PPAR Isoforms

All PI3K Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(+)-Licarin Related Classifications

HY-N12338 Related Classifications