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Results for "

pH indicator

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (3) Biochemical Assay Reagents (19) Cytochrome P450 (1) Environmental Pollutants (10) Fluorescent Dye (43) Glutathione Peroxidase (1) HIV (3) Isotope-Labeled Compounds (2) Reference Standards (4)
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Isotope-Labeled Compounds

Targets Recommended: HIF/HIF Prolyl-Hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0169

Phenol Red 1 Publications Verification pHenolsulfonepHthalein	Environmental Pollutants Fluorescent Dye	Others
Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-101883

BCECF-AM	Fluorescent Dye	Others
BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. BCECF-AM could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-B1571

Bromophenol blue	Environmental Pollutants Fluorescent Dye	Others
Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .

HY-D0166

Neutral Red	Fluorescent Dye	Others
Neutral Red, a nitrogenous pH-indicator with a pK_i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red .

HY-133527

OG 488, SE Oregon green 488 succinimidyl ester	Fluorescent Dye	Neurological Disease
OG 488, SE (Oregon green 488 succinimidyl ester), a fluorescent pH indicator, has many applications in biochemistry and neurosciences .

HY-D0023

Pyranine 2 Publications Verification HPTS; Solvent Green 7	Environmental Pollutants Fluorescent Dye	Others
Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-B1422

9-Aminoacridine 4 Publications Verification Aminacrine	Bacterial HIV	Infection
9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

HY-D0012

Bromothymol Blue	Environmental Pollutants Fluorescent Dye	Others
Bromothymol Blue is a pH indicator.

HY-W110798

*Bromophenol blue indicator* (3.0-4.6)** 1 Publications Verification	Environmental Pollutants Biochemical Assay Reagents	Others
Bromophenol blue indicator (3.0-4.6) is a synthetic dye commonly used as an acid-base indicator with a transition range of pH 3.0-4.6. Bromophenol blue indicator (3.0-4.6) is water soluble and changes color from yellow to blue as the pH of the solution changes from acidic to basic. Its unique chemical properties make it an important ingredient in a variety of scientific applications, especially in biochemistry and molecular biology. In addition, it can be used as a stain in microbiology and histology. However, Bromophenol blue indicator (3.0-4.6) has potential irritating and staining properties.

HY-118907

Methyl Orange	Fluorescent Dye	Others
Methyl Orange is a soluble azo dye commonly used as an acid-base indicator and for staining cells and tissue sections, as well as for dyeing textiles. Methyl Orange appears red at a pH of 3.1 and changes to bright yellow as the pH increases to 4.4. Methyl Orange (500 mg/L) exhibits cytotoxicity and can cause DNA damage .

HY-W040144

Bromocresol green	Fluorescent Dye	Others
Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

HY-Y0699

Methyl red	Environmental Pollutants Fluorescent Dye	Others
Methyl red is a pH-sensitive acid-base indicator and colorimetric reagent with a pKa of 5.1. Methyl red achieves visual judgment of the titration endpoint through reversible structural changes of protonation (red, pH <4.4) and deprotonation (yellow, pH >6.2). Methyl red is widely used in acid-base titration in chemical analysis and buffer pH monitoring in biochemistry .

HY-D0219

Thymol blue ThymolsulpHonepHthalein	Fluorescent Dye	Others
Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI ^- form) under acidic conditions and blue (I ^2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].

HY-D0169A

Phenol Red sodium salt 1 Publications Verification pHenolsulfonepHthalein sodium salt	Fluorescent Dye Glutathione Peroxidase	Others
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .

HY-D1445

LysoSensor PDMPO 1 Publications Verification	Fluorescent Dye	Metabolic Disease
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .

HY-126774

DAF-FM 1 Publications Verification	Fluorescent Dye	Others
DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .

HY-101883A

BCECF Acetoxymethyl ester Maximum Cited Publications 10 Publications Verification	Fluorescent Dye	Others
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .

HY-D0077

2',7'-Difluorofluorescein Oregon green 488	Fluorescent Dye	Others
2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pK_a ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca ²⁺ indicators, a fluorescent imaging agent, and an anisotropy probe .

HY-W110794

Crystal violet, IND (0.0-2.0)	Environmental Pollutants Biochemical Assay Reagents	Others
Crystal violet, IND (0.0-2.0) is a specialized indicator suitable for strongly acidic systems, which reflects changes in pH within the range of 0.0-2.0 through color changes. Crystal violet, IND (0.0-2.0) is widely used in acid-base titration, chemical analysis, and industrial testing fields .

HY-D0202

Arsenazo III	Fluorescent Dye	Others
Arsenazo III is an azo derivative of chromotropic acid, a metal chrome dye, a chelating agent, and a cation complexing agent. Arsenazo III forms stable 1:1 complexes with Ca ²⁺, Mg ²⁺, Sr ²⁺, Ba ²⁺, K ⁺, and Na ⁺, and its binding affinity for Ca ²⁺ depends on pH, alkali metal cation concentration, and buffer parameters. Arsenazo III serves as a colorimetric indicator for micromolar ionized Ca ²⁺ in cells .

HY-W087928

Bromocresol purple	Biochemical Assay Reagents	Others
Bromocresol purple is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .

HY-125457

α-Naphtholbenzein p-NapHtolbenzein	Biochemical Assay Reagents	Others
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein is commonly used in experiments such as acid-base neutralization reactions, titration, and pH measurement .

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Environmental Pollutants Fluorescent Dye	Others
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release .

HY-W151206

Hydroxy naphthol blue disodium	Fluorescent Dye	Others
Hydroxy naphthol blue disodium is an azo dye compound commonly used as an acid-base indicator (λmax = 650 nm). Within the pH range of 12 to 13, the indicator solution of Hydroxy naphthol blue disodium appears pale red in the presence of calcium ions and dark blue in the presence of disodium EDTA .

HY-128369

Acid Yellow 36 Metanil Yellow	Environmental Pollutants Cytochrome P450	Others
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

HY-D0265

Thymolphthalein	Environmental Pollutants Fluorescent Dye	Others
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .

HY-D0228

4-(4-Nitrophenylazo)resorcinol Azo Violet; Magneson I	Fluorescent Dye	Others
4-(4-Nitrophenylazo)resorcinol (Azo Violet) is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used .

HY-D1677

5(6)-Carboxynaphthofluorescein	Fluorescent Dye	Others
5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm) .

HY-D2482

Asante potassium green-1 AM APG-1 AM	Fluorescent Dye	Neurological Disease
Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K ⁺-sensitive fluorescent indicator and potassium ion indicator that exhibits minimal interference from Na ⁺ and pH at physiologically relevant intracellular levels. Asante potassium green-1 AM enables non-invasive monitoring and quantitative analysis of intracellular potassium ion concentration (ᵢ) . Its excitation/emission maxima are 525/545 nm, respectively.

HY-D1401

OG 488, acid	Fluorescent Dye	Others
OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences .

HY-128545

Nitrazine yellow Nitrazine paper; pHenapHthazine	Biochemical Assay Reagents	Others
Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .

HY-D0252

m-Cresol purple	Fluorescent Dye	Others
m-Cresol purple is a pH indicator dye with large cross section and halochromic property in neutral pH range .

HY-D1556

18:1 PE CF 1,2-dioleoyl-sn-glycero-3-pHospHoethanolamine-N-(carboxyfluorescein) ammonium	Fluorescent Dye	Cancer
18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .

HY-D0219A

Thymol Blue sodium	Fluorescent Dye	Others
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .

HY-118320

Alizarine Yellow R Mordant orange 1	Fluorescent Dye	Others
Alizarine Yellow R (Mordant orange 1), Salicylic acid derivative (HY-B0167), is an azo dye. Alizarine Yellow R is used as a pH indicator and a biological stain in chemical examinations and dyeing industries .

HY-W331502

Chlorophenol Red sodium	Fluorescent Dye	Others
Chlorophenol Red sodium is a pH indicator .

HY-D0012A

Bromothymol Blue sodium	Biochemical Assay Reagents	Others
Bromothymol Blue sodium salt is a pH indicator. Storage: protect from light.

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dye	Others
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-N8502

Urdamycin A	Fluorescent Dye	Cancer
Urdamycin A (Compound 3b) is an angucycline antibiotic that can be isolated from Streptomyces fradiae. Urdamycin A is an orange indicator with a change of the color to ultramarine blue at pH 7.7. Urdamycin A has anticancer activity with IC₅₀s of 2.4 and 0.55 μg/mL in proliferation and stem cell assays, respectively .

HY-D0276

m-Cresol purple sodium Metacresol purple sodium	Biochemical Assay Reagents	Others
m-Cresol purple sodium (Metacresol purple sodium) is a pH indicator. m-Cresol purple sodium solution from yellow to blue in the pH range from 7.5 to 9.0 .

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dye	Others
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .

HY-W025785

Methyl yellow Solvent Yellow 2; Dimethyl yellow	Biochemical Assay Reagents	Cancer
Methyl yellow (Solvent Yellow 2) is a pH indicator. Methyl yellow appears red at low pH, and becomes yellow above pH 4.0 .

HY-D0015

Cresol red, 97%	Fluorescent Dye	Others
Cresol red, 97% is an acidic phenolsulfonphthalein triphenylmethane dye. Cresol red, 97% generates reactive oxygen species and singlet oxygen under ultrasonic irradiation, interacts with bovine serum albumin, alters the structure of bovine serum albumin, and oxidizes the fluorescent amino acid residues of bovine serum albumin. Cresol red, 97% can be decolorized and biodegraded by Absidia spinosa M15, producing phenylacetic acid and benzoic acid metabolites. Cresol red, 97% serves as a pH indicator (orange at pH 1.8-yellow at pH 2.0, yellow at pH 7.0-purple at pH 8.8). Cresol red, 97% can be used to indicate pH, temperature and salinity .

HY-Y0699R

Methyl red (Standard)	Fluorescent Dye Reference Standards	Others
Methyl red (Standard) is the analytical standard of Methyl red. This product is intended for research and analytical applications. Methyl red is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-W110790

Bromocresol purple sodium	Biochemical Assay Reagents	Others
Bromocresol purple sodium is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple sodium can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .

HY-W110789

*Ethyl Orange sodium, indicator* grade**	Biochemical Assay Reagents	Others
Ethyl Orange (sodium), indicator grade is an organic azo compound that can be used as a pH indicator from pH 3.0 to pH 4.8, changing color from red to orange.

HY-W088071

Litmus	Biochemical Assay Reagents	Others
Litmus is a pH indicator, which is red at pH 4.5 and blue at pH 8.3.

HY-D0011

Brom0phenol blue sodium 1 Publications Verification	Biochemical Assay Reagents	Others
Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis .

HY-D0015A

Cresol Red sodium	Fluorescent Dye	Others
Cresol Red sodium is a triarylmethane dye. Cresol Red sodium can be used for indicating pH, temperatures and salinities .

HY-W087913

alpha-Naphtholphthalein	Biochemical Assay Reagents	Others
alpha-Naphtholphthalein is an indicator that is light yellow at pH 6 and gradually shows a clear color change with increasing pH to light green-green-blue. alpha-Naphtholphthalein can be impregnated into cotton-blend fabrics and used to develop medical supplies for wound pH monitoring, such as medical gauze, hospital gowns and compression bandages .

Cat. No.	Product Name	Type

HY-D0169

Phenol Red 1 Publications Verification pHenolsulfonepHthalein	Fluorescent Dye
Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .

HY-101883

BCECF-AM	Fluorescent Dye
BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. BCECF-AM could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-B1571

Bromophenol blue

Fluorescent Dye

Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .

HY-D0166

Neutral Red	Fluorescent Dye
Neutral Red, a nitrogenous pH-indicator with a pK_i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red .

HY-133527

OG 488, SE Oregon green 488 succinimidyl ester	Fluorescent Dye
OG 488, SE (Oregon green 488 succinimidyl ester), a fluorescent pH indicator, has many applications in biochemistry and neurosciences .

HY-D0023

Pyranine 2 Publications Verification HPTS; Solvent Green 7	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-B1422

9-Aminoacridine

4 Publications Verification

Aminacrine

Fluorescent Dye

9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

HY-D0012

Bromothymol Blue	Fluorescent Dye
Bromothymol Blue is a pH indicator.

HY-D0219

Thymol blue

ThymolsulpHonepHthalein

Fluorescent Dye

Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI ^- form) under acidic conditions and blue (I ^2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].

HY-D0169A

Phenol Red sodium salt 1 Publications Verification pHenolsulfonepHthalein sodium salt	Fluorescent Dye
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .

HY-D1445

LysoSensor PDMPO

1 Publications Verification

Fluorescent Dye

PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .

HY-126774

DAF-FM 1 Publications Verification	Fluorescent Dye
DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .

HY-101883A

BCECF Acetoxymethyl ester Maximum Cited Publications 10 Publications Verification	Fluorescent Dye
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .

HY-D0202

Arsenazo III

Fluorescent Dye

Arsenazo III is an azo derivative of chromotropic acid, a metal chrome dye, a chelating agent, and a cation complexing agent. Arsenazo III forms stable 1:1 complexes with Ca ²⁺, Mg ²⁺, Sr ²⁺, Ba ²⁺, K ⁺, and Na ⁺, and its binding affinity for Ca ²⁺ depends on pH, alkali metal cation concentration, and buffer parameters. Arsenazo III serves as a colorimetric indicator for micromolar ionized Ca ²⁺ in cells .

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Fluorescent Dye
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release .

HY-W151206

Hydroxy naphthol blue disodium	Fluorescent Dye
Hydroxy naphthol blue disodium is an azo dye compound commonly used as an acid-base indicator (λmax = 650 nm). Within the pH range of 12 to 13, the indicator solution of Hydroxy naphthol blue disodium appears pale red in the presence of calcium ions and dark blue in the presence of disodium EDTA .

HY-128369

Acid Yellow 36 Metanil Yellow	Fluorescent Dye
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

HY-D0265

Thymolphthalein	Fluorescent Dye
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .

HY-D0228

4-(4-Nitrophenylazo)resorcinol

Azo Violet; Magneson I

Fluorescent Dye

4-(4-Nitrophenylazo)resorcinol (Azo Violet) is an azo purple dye used experimentally as a pH indicator, showing yellow when the pH value is lower than 11 and purple when the pH value is higher than 13. In slightly alkaline or alkaline environments, it also turns dark blue in the presence of magnesium salts. Azo Violet can also be used to test for the presence of ammonium ions. The color of the ammonium chloride or ammonium hydroxide solution will change depending on the concentration of azo violet used .

HY-D2482

Asante potassium green-1 AM

APG-1 AM

Fluorescent Dye

Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K ⁺-sensitive fluorescent indicator and potassium ion indicator that exhibits minimal interference from Na ⁺ and pH at physiologically relevant intracellular levels. Asante potassium green-1 AM enables non-invasive monitoring and quantitative analysis of intracellular potassium ion concentration (ᵢ) . Its excitation/emission maxima are 525/545 nm, respectively.

HY-D1401

OG 488, acid	Fluorescent Dye
OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences .

HY-D0252

m-Cresol purple	Fluorescent Dye
m-Cresol purple is a pH indicator dye with large cross section and halochromic property in neutral pH range .

HY-D1556

18:1 PE CF

1,2-dioleoyl-sn-glycero-3-pHospHoethanolamine-N-(carboxyfluorescein) ammonium

Fluorescent Dye

18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .

HY-D0219A

Thymol Blue sodium

Fluorescent Dye

Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .

HY-118320

Alizarine Yellow R Mordant orange 1	Fluorescent Dye
Alizarine Yellow R (Mordant orange 1), Salicylic acid derivative (HY-B0167), is an azo dye. Alizarine Yellow R is used as a pH indicator and a biological stain in chemical examinations and dyeing industries .

HY-W331502

Chlorophenol Red sodium	Fluorescent Dye
Chlorophenol Red sodium is a pH indicator .

HY-D0012A

Bromothymol Blue sodium	Fluorescent Dye
Bromothymol Blue sodium salt is a pH indicator. Storage: protect from light.

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dye
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dye
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .

HY-D0015

Cresol red, 97%

Fluorescent Dye

Cresol red, 97% is an acidic phenolsulfonphthalein triphenylmethane dye. Cresol red, 97% generates reactive oxygen species and singlet oxygen under ultrasonic irradiation, interacts with bovine serum albumin, alters the structure of bovine serum albumin, and oxidizes the fluorescent amino acid residues of bovine serum albumin. Cresol red, 97% can be decolorized and biodegraded by *Absidia spinosa* M15, producing phenylacetic acid and benzoic acid metabolites. Cresol red, 97% serves as a pH indicator (orange at pH 1.8-yellow at pH 2.0, yellow at pH 7.0-purple at pH 8.8). Cresol red, 97% can be used to indicate pH, temperature and salinity .

HY-D0011

Brom0phenol blue sodium 1 Publications Verification	Fluorescent Dye
Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis .

HY-D0015A

Cresol Red sodium	Fluorescent Dye
Cresol Red sodium is a triarylmethane dye. Cresol Red sodium can be used for indicating pH, temperatures and salinities .

HY-D0009

Bromocresol green sodium	Fluorescent Dye
Bromocresol green sodium is an anionic dye. Bromocresol green sodium can be used for pH indication and DNA agarose gel electrophoresis. Bromocresol green sodium is also used in mammalian albumin measurement. Bromocresol green sodium deprotonates and produces the monoanionic form of yellow colour at lower pH (acidic condition), and produces dianionic blue colour at the basic condition .

HY-B1422R

9-Aminoacridine (Standard)

Aminacrine (Standard)

Fluorescent Dye

9-Aminoacridine (Standard) is the analytical standard of 9-Aminoacridine. This product is intended for research and analytical applications. 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

HY-D0023A

Pyranine hydrate HPTS hydrate; Solvent Green 7 hydrate	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) hydrate is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine hydrate acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine hydrate is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-D0116

Pyranine free acid HPTS free acid; Solvent Green 7 free acid	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) free acid is a pH-sensitive fluorescent indicator. Pyranine free acid acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine free acid is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-D1477

5(6)-Carboxyfluorescein diisobutyrate	Fluorescent Dye
5(6)-Carboxyfluorescein diisobutyrate is a protected 5(6)-carboxyfluorescein. 5(6)-carboxyfluorescein is a fluorescence pH indicator .

HY-131510

Chromoionophore XIII SNARF-DE	Fluorescent Dye
Chromoionophore XIII (SNARF-DE) is a pH senor that enables excitation with red light. Chromoionophore XIII functionality renders the indicator molecule lipophilic and water-insoluble but also prevents lactonization of the dye in an apolar environment .

HY-W411215

1,4-Diacetoxy-2,3-dicyanobenzene	Fluorescent Dye
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH .

HY-D3036

5-(6)-Carboxy SNAFL-1 SE	Fluorescent Dye
5-(6)-Carboxy SNAFL-1 SE is an amine-reactive succinimidyl ester pH indicator. 5-(6)-Carboxy SNAFL-1 SE can be readily conjugated to peptides, antibodies and other amino-containing molecules such as amino-modified oligos. 5-(6)-Carboxy SNAFL-1 SE can be used for measurement of pH changes between 7-8 (Ex/Em = 490/513 nm) .

Cat. No.	Product Name	Type

HY-W110798

Bromophenol blue indicator (3.0-4.6)

1 Publications Verification

Biochemical Assay Reagents

Bromophenol blue indicator (3.0-4.6) is a synthetic dye commonly used as an acid-base indicator with a transition range of pH 3.0-4.6. Bromophenol blue indicator (3.0-4.6) is water soluble and changes color from yellow to blue as the pH of the solution changes from acidic to basic. Its unique chemical properties make it an important ingredient in a variety of scientific applications, especially in biochemistry and molecular biology. In addition, it can be used as a stain in microbiology and histology. However, Bromophenol blue indicator (3.0-4.6) has potential irritating and staining properties.

HY-W040144

Bromocresol green

Biochemical Assay Reagents

Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells .

HY-Y0699

Methyl red	Biochemical Assay Reagents
Methyl red is a pH-sensitive acid-base indicator and colorimetric reagent with a pKa of 5.1. Methyl red achieves visual judgment of the titration endpoint through reversible structural changes of protonation (red, pH <4.4) and deprotonation (yellow, pH >6.2). Methyl red is widely used in acid-base titration in chemical analysis and buffer pH monitoring in biochemistry .

HY-W110794

Crystal violet, IND (0.0-2.0)	Biochemical Assay Reagents
Crystal violet, IND (0.0-2.0) is a specialized indicator suitable for strongly acidic systems, which reflects changes in pH within the range of 0.0-2.0 through color changes. Crystal violet, IND (0.0-2.0) is widely used in acid-base titration, chemical analysis, and industrial testing fields .

HY-W087928

Bromocresol purple	Biochemical Assay Reagents
Bromocresol purple is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .

HY-125457

α-Naphtholbenzein p-NapHtolbenzein	Biochemical Assay Reagents
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein is commonly used in experiments such as acid-base neutralization reactions, titration, and pH measurement .

HY-D0265

Thymolphthalein	Biochemical Assay Reagents
Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH .

HY-128545

Nitrazine yellow Nitrazine paper; pHenapHthazine	Biochemical Assay Reagents
Nitrazine yellow (Nitrazine paper; Phenaphthazine) is a pH indicator. The color of Nitrazine yellow changes from yellow to blue in the pH range from 6.0 to 7.0. Nitrazine yellow is a kind of biological materials or organic compounds that are widely used in life science research .

HY-D0252

m-Cresol purple	Biochemical Assay Reagents
m-Cresol purple is a pH indicator dye with large cross section and halochromic property in neutral pH range .

HY-D0276

m-Cresol purple sodium Metacresol purple sodium	Biochemical Assay Reagents
m-Cresol purple sodium (Metacresol purple sodium) is a pH indicator. m-Cresol purple sodium solution from yellow to blue in the pH range from 7.5 to 9.0 .

HY-D0015

Cresol red, 97%

Biochemical Assay Reagents

HY-Y0699R

Methyl red (Standard)	Biochemical Assay Reagents
Methyl red (Standard) is the analytical standard of Methyl red. This product is intended for research and analytical applications. Methyl red is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-W110790

Bromocresol purple sodium	Biochemical Assay Reagents
Bromocresol purple sodium is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple sodium can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .

HY-W110789

*Ethyl Orange sodium, indicator* grade**	Biochemical Assay Reagents
Ethyl Orange (sodium), indicator grade is an organic azo compound that can be used as a pH indicator from pH 3.0 to pH 4.8, changing color from red to orange.

HY-W088071

Litmus	Biochemical Assay Reagents
Litmus is a pH indicator, which is red at pH 4.5 and blue at pH 8.3.

HY-D0011

Brom0phenol blue sodium 1 Publications Verification	Biochemical Assay Reagents
Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis .

HY-W087913

alpha-Naphtholphthalein	Biochemical Assay Reagents
alpha-Naphtholphthalein is an indicator that is light yellow at pH 6 and gradually shows a clear color change with increasing pH to light green-green-blue. alpha-Naphtholphthalein can be impregnated into cotton-blend fabrics and used to develop medical supplies for wound pH monitoring, such as medical gauze, hospital gowns and compression bandages .

HY-W342120

Phenolphthalein disodium, 95%	Biochemical Assay Reagents
Phenolphthalein (disodium), 95% is a pH indicator.

HY-W145108

Methyl red hydrochloride	Biochemical Assay Reagents
Methyl red hydrochloride is an azo dye that acts as a pH indicator. Methyl red is red and yellow at pH 4.4 and 6.0 respectively .

HY-W016352

2-Hydroxy-5-nitrobenzoic acid, 99% Anilotic acid, 99%	Biochemical Assay Reagents
2-Hydroxy-5-nitrobenzoic acid, 99% is used as an HPLC analytical standard, pH indicator, and heavy metal detection agent, and is also used in the study of phenolic compounds oxidation.

HY-W110784

Ethyl red, 98% Diethyl red, 98%	Biochemical Assay Reagents
Ethyl Red, 98% is a pH indicator.

HY-W016352R

2-Hydroxy-5-nitrobenzoic acid, 99% (Standard) Anilotic acid, 99% (Standard)	Biochemical Assay Reagents
2-Hydroxy-5-nitrobenzoic acid, 99% (Standard) is the analytical standard of 2-Hydroxy-5-nitrobenzoic acid, 99%. This product is intended for research and analytical applications. 2-Hydroxy-5-nitrobenzoic acid, 99% is used as an HPLC analytical standard, pH indicator, and heavy metal detection agent, and is also used in the study of phenolic compounds oxidation.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8502

Urdamycin A	Microorganisms Antibiotics Source Classification	Fluorescent Dye
Urdamycin A (Compound 3b) is an angucycline antibiotic that can be isolated from Streptomyces fradiae. Urdamycin A is an orange indicator with a change of the color to ultramarine blue at pH 7.7. Urdamycin A has anticancer activity with IC₅₀s of 2.4 and 0.55 μg/mL in proliferation and stem cell assays, respectively .

Cat. No.	Product Name	Chemical Structure

HY-B1422S

9-Aminoacridine-13C6

9-Aminoacridine-13C6 is the ¹³C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

HY-W025785S1

Methyl yellow-d6
Methyl yellow-d₆ (Solvent Yellow 2-d₆) is the deuterium labeled Methyl yellow (HY-W025785). Methyl yellow (Solvent Yellow 2) is a pH indicator. Methyl yellow appears red at low pH, and becomes yellow above pH 4.0 .

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