3203 Results for "

plasma polymerized 2,6-diethylaniline thin films

" in MedChemExpress (MCE) Product Catalog:
Products (3203)

3203 Results for "plasma polymerized 2,6-diethylaniline thin films" in MCE Product Catalog:

396
Paclitaxel
Paclitaxel
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396 Publications Verification
Art. -Nr.: HY-B0015
CAS. Nr.: 33069-62-4
Category:  

Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.

Target:  

Microtubule/Tubulin ADC Payloads Apoptosis Autophagy

Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
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245
JC-1
JC-1
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245 Cited Publications
Art. -Nr.: HY-15534
CAS. Nr.: 3520-43-2
Reinheit:  98.71%
Synonyms: CBIC2
JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) .
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223
PEG300
PEG300
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223 Cited Publications
Art. -Nr.: HY-Y0873
CAS. Nr.: 25322-68-3
Synonyms: Polyethylene glycol 300
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .
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194
Thiazolyl Blue
Thiazolyl Blue
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194 Cited Publications
Art. -Nr.: HY-15924
CAS. Nr.: 298-93-1
Synonyms: MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
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118
Hexadimethrine bromide
Hexadimethrine bromide
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118 Cited Publications
Art. -Nr.: HY-112735
CAS. Nr.: 28728-55-4
Reinheit:  99.69%
Synonyms: Polybrene; 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
Hexadimethrine bromide (Polybrene) is a cationic polymer used routinely to enhance the efficiency of retrovirus vector-mediated gene transfer .
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104
Cytochalasin D
Cytochalasin D
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104 Cited Publications
Art. -Nr.: HY-N6682
CAS. Nr.: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

Exosomes Arp2/3 Complex Antibiotic YAP

Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .
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95
Cholesterol (from animal)
Cholesterol (from animal)
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95 Cited Publications
Art. -Nr.: HY-N0322
CAS. Nr.: 57-88-5
Category:  

Metabolic Disease Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

Endogenous Metabolite Estrogen Receptor/ERR Bacterial Liposome

Cholesterol (from animal) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (from animal) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol (from animal) is also an endogenous estrogen-related receptor α (ERRα) agonist .
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95
Cholesterol (Water Soluble)
Cholesterol (Water Soluble)
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95 Cited Publications
Art. -Nr.: HY-N0322A
Category:  

Other Diseases Endogenous metabolite Disease Research Fields Steroids

Target:  

Liposome

Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
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79
Vincristine
Vincristine
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79 Cited Publications
Art. -Nr.: HY-N0488A
CAS. Nr.: 57-22-7
Synonyms: Leurocristine; NSC-67574; 22-Oxovincaleukoblastine
Category:  

Apocynaceae Alkaloids Plants Disease Research Fields Cancer Alkaloid Dimers Catharanthus roseus (L.) G. Don

Target:  

Apoptosis Microtubule/Tubulin Mitosis

Vincristine (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a Ki of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .
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79
Vincristine sulfate
Vincristine sulfate
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79 Cited Publications
Art. -Nr.: HY-N0488
CAS. Nr.: 2068-78-2
Synonyms: Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate
Category:  

Apocynaceae Alkaloids Anti-aging Plants Disease Research Fields Cancer Alkaloid Dimers Catharanthus roseus (L.) G. Don

Target:  

Apoptosis Microtubule/Tubulin Mitosis

Vincristine (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) sulfate is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a Ki of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .
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77
Colchicine
Colchicine
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77 Cited Publications
Art. -Nr.: HY-16569
CAS. Nr.: 64-86-8
Category:  

Natural Products other families Plants Disease Research Fields Cancer

Target:  

Environmental Pollutants Apoptosis Autophagy Microtubule/Tubulin NOD-like Receptor (NLR)

Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .
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61
Monomethyl auristatin E
Monomethyl auristatin E
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61 Cited Publications
Art. -Nr.: HY-15162
CAS. Nr.: 474645-27-7
Reinheit:  99.97%
Synonyms: MMAE; SGD-1010
Target:  

Microtubule/Tubulin ADC Payloads Apoptosis

Forschungsgebiete:  

Cancer

Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
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59
Nystatin
Nystatin
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59 Cited Publications
Art. -Nr.: HY-17409
CAS. Nr.: 1400-61-9
Category:  

Infection Microorganisms Macrolide Antibiotics Antifungal Antibiotics Mammalian Cell Culture Disease Research Disease Research Fields

Target:  

Fungal Antibiotic Apoptosis Bacterial

Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion . Nystatin is a cholesterol-sequestering agent , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis .
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47
Cytochalasin B
Cytochalasin B
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47 Cited Publications
Art. -Nr.: HY-16928
CAS. Nr.: 14930-96-2
Synonyms: Phomin
Category:  

Natural Products Microorganisms Disease Research Fields Cancer

Target:  

Arp2/3 Complex

Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.
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43
PolyFast Transfection Reagent
PolyFast Transfection Reagent
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43 Cited Publications
Art. -Nr.: HY-K1014

MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

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32
High Sensitivity ECL Kit
High Sensitivity ECL Kit
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32 Cited Publications
Art. -Nr.: HY-K2005

High Sensitivity ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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21
L-Lactic acid
L-Lactic acid
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21 Cited Publications
Art. -Nr.: HY-Y0479
CAS. Nr.: 79-33-4
Synonyms: (S)-2-Hydroxypropanoic acid
Category:  

Endocrine diseases Endogenous metabolite Infection Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder

Target:  

Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial

L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity .
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21
L-Lactic acid sodium
L-Lactic acid sodium
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21 Cited Publications
Art. -Nr.: HY-W040233
CAS. Nr.: 867-56-1
Synonyms: (S)-2-Hydroxypropanoic acid sodium
Target:  

Environmental Pollutants Antibiotic Endogenous Metabolite Drug Intermediate Bacterial

Forschungsgebiete:  

Infection Cancer

L-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity .
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21
Hyaluronic acid sodium
Hyaluronic acid sodium
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21 Cited Publications
Art. -Nr.: HY-B0633
CAS. Nr.: 9067-32-7
Synonyms: Sodium hyaluronate
Category:  

Microorganisms Animals Cosmetic Research Disease Research Fields Saccharides Cancer

Target:  

Endogenous Metabolite Bacterial PI3K Akt

Hyaluronic acid sodium (Sodium hyaluronate) is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). Hyaluronic acid sodium is synthesized at the plasma membrane. Increased hyaluronic acid sodium levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid sodium participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid sodium activates the PI3K-Akt signaling. Hyaluronic acid sodium acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid sodium can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid sodium can be studied in joint diseases, wound healing and cancer .
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21
Hyaluronic acid
Hyaluronic acid
0 Images
21 Cited Publications
Art. -Nr.: HY-B0633A
CAS. Nr.: 9004-61-9
Synonyms: Hyaluronan; Hyaluronate
Category:  

Zea mays L. Moisture Plants Endogenous metabolite Human Gut Microbiota Metabolites Polysaccharides Gramineae Cosmetic Research Disease Research Fields Saccharides Cancer

Target:  

Endogenous Metabolite Bacterial Akt PI3K

Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications. Hyaluronic acid is a major component of the extracellular matrix (ECM). Hyaluronic acid is synthesized at the plasma membrane. Increased hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion and angiogenesis in digestive cancers. Hyaluronic acid participates in tissue remodeling and rapid cell proliferation in some physiological processes including embryonic morphogenesis and wound-healing. Hyaluronic acid activates the PI3K-Akt signaling. Hyaluronic acid acts as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting proteolytic MMP-9 binding to cell surface or stimulating MMP-9 binding to cell surface. Hyaluronic acid can be used as drug delivery for sodium butyrate to improve the anti-proliferative activity on breast cancer cell line. Hyaluronic acid can be studied in joint diseases, wound healing and cancer .
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