131 Results for "

tertiary ammonia

" in MedChemExpress (MCE) Product Catalog:
Products (131)

131 Results for "tertiary ammonia" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-B1142
CAS No.: 940-69-2
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
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8
8 Cited Publications
Cat. No.: HY-B1490
CAS No.: 113-52-0
Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects .
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8
8 Cited Publications
Cat. No.: HY-B1490A
CAS No.: 50-49-7
Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects .
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7
7 Cited Publications
Cat. No.: HY-B1692
CAS No.: 15985-39-4
Synonyms: MSX; MSO
Target:  

Glutaminase

Research Areas:  

Neurological Disease

L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
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2
2 Cited Publications
Cat. No.: HY-W004494
CAS No.: 141120-17-4
Research Areas:  

Others

2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche .
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2
2 Cited Publications
Cat. No.: HY-W017692
CAS No.: 1416354-35-2
Research Areas:  

Metabolic Disease

2-Aminoindan-2-phosphonic acid hydrochloride is a competitive phenylalanine ammonia lyase (PAL) inhibitor that significantly decreases the levels of total phenolic compounds and PheGs in plant cultured cells .
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1
1 Cited Publications
Cat. No.: HY-P2767
CAS No.: 9002-13-5
Target:  

Bacterial

Research Areas:  

Others

Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.
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1
1 Cited Publications
Cat. No.: HY-B2087
CAS No.: 611168-24-2
Synonyms: HPN-100
Target:  

Sigma Receptor

Research Areas:  

Cardiovascular Disease

Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .
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1
1 Cited Publications
Cat. No.: HY-117147A
CAS No.: 2517771-89-8
Purity:  99.69%
Target:  

REV-ERB Cytochrome P450

Research Areas:  

Metabolic Disease

GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism .
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1
1 Cited Publications
Cat. No.: HY-W009444
CAS No.: 1463-10-1
5-Methyluridine (m 5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA), which mainly targets specific uracil sites in RNA molecules such as the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing .
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1
1 Cited Publications
Cat. No.: HY-N10574
CAS No.: 72496-59-4
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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1
1 Cited Publications
Cat. No.: HY-N10574A
CAS No.: 86496-18-6
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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Cat. No.: HY-B1571
CAS No.: 115-39-9
Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .
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Cat. No.: HY-N6662
CAS No.: 475-20-7
(+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
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Cat. No.: HY-B0543
CAS No.: 109-57-9
Synonyms: Thiosinamine; N-Allylthiourea
Research Areas:  

Cancer

Allylthiourea can selectively inhibit the oxidation of ammonia. Allylthiourea is commonly used to inhibit nitrification by targeting ammonia monooxygenase and chelating copper in the active site to suppress its activity. Allylthiourea also exhibits anticancer activity, showing cytotoxicity against the MCF-7 cell line with an IC50 of 5.22 mM. Allylthiourea can be utilized in research related to micropollutant biodegradability and cancer studies .
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Cat. No.: HY-A0282
CAS No.: 3230-94-2
L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions .
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Cat. No.: HY-100956
CAS No.: 70788-28-2
Purity:  ≥92.0%
Target:  

Bacterial Urease

Research Areas:  

Infection Metabolic Disease

Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones .
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Cat. No.: HY-W250144
CAS No.: 27176-87-0
Synonyms: Dodecylbenzenesulphonic acid
Dodecylbenzenesulfonic acid (Dodecylbenzenesulphonic acid) is an anionic surfactant. Dodecylbenzenesulfonic acid serves as a raw material for various detergents. Dodecylbenzenesulfonic acid can be used as a cleaning agent in the daily chemical industry or a chemical oil-displacing agent in tertiary oil recovery .
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Cat. No.: HY-E70003
CAS No.: 9001-46-1
Research Areas:  

Endocrinology

Glutamate dehydrogenase is an enzyme in both prokaryotes and eukaryotic mitochondria. Glutamate dehydrogenase can be used for the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate and urease .
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Cat. No.: HY-W019334
CAS No.: 202842-98-6
Synonyms: 3,4-DMPP
Target:  

Bacterial

Research Areas:  

Others

3,4-Dimethylpyrazole phosphate (3,4-DMPP) is a nitrification inhibitor and microbial community regulator, whose activity is dose- and soil pH-dependent. 3,4-Dimethylpyrazole phosphate inhibits ammonia monooxygenase, ammonia-oxidizing bacteria, as well as ammonia-oxidizing archaea and nitrite-oxidizing bacteria. 3,4-Dimethylpyrazole phosphate alters the community composition of prokaryotes, fungi and ammonia-oxidizing bacteria. 3,4-Dimethylpyrazole phosphate reduces nitrate leaching, nitrous oxide emission and soil nitrate accumulation, and enhances nitrogen use efficiency and crop yield in agricultural production. 3,4-Dimethylpyrazole phosphate is applicable to agriculture-related research .
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