71 Results for "

trihydrate

" in MedChemExpress (MCE) Product Catalog:
Products (71)

71 Results for "trihydrate" in MCE Product Catalog:

173
173 Publications Verification
Art. -Nr.: HY-B2176A
CAS. Nr.: 51963-61-2
Synonyms: Adenosine-5'-triphosphate disodium trihydrate
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
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172
172 Cited Publications
Art. -Nr.: HY-B0011A
CAS. Nr.: 148408-66-6
Synonyms: RP-56976 trihydrate
Forschungsgebiete:  

Cancer

Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis .
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86
86 Cited Publications
Art. -Nr.: HY-B0522B
CAS. Nr.: 7177-48-2
Synonyms: D-(-)-α-Aminobenzylpenicillin trihydrate
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
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81
81 Cited Publications
Art. -Nr.: HY-16568
CAS. Nr.: 136572-09-3
Synonyms: (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate
Target:  

Topoisomerase Autophagy

Forschungsgebiete:  

Cancer

Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity .
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69
69 Cited Publications
Art. -Nr.: HY-112490
CAS. Nr.: 344423-98-9
Reinheit:  99.64%
Forschungsgebiete:  

Cardiovascular Disease Others

Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
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67
67 Cited Publications
Art. -Nr.: HY-B0589E
CAS. Nr.: 344920-08-7
Atorvastatin hemicalcium trihydrate is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium trihydrate inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively .
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38
38 Cited Publications
Art. -Nr.: HY-13074
CAS. Nr.: 476310-60-8
Reinheit:  ≥98.0%
Target:  

PTEN Autophagy

Forschungsgebiete:  

Cancer

VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC50 of 46±10 nM.
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34
34 Cited Publications
Art. -Nr.: HY-13678A
CAS. Nr.: 119478-56-7
Reinheit:  99.85%
Synonyms: SM 7338 trihydrate
Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
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34
34 Cited Publications
Art. -Nr.: HY-W013075
CAS. Nr.: 250249-75-3
Synonyms: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate
Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities .
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30
30 Cited Publications
Art. -Nr.: HY-B1359
CAS. Nr.: 7220-79-3
Synonyms: C.I. Basic Blue 9 trihydrate
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .
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23
23 Cited Publications
Art. -Nr.: HY-B0467B
CAS. Nr.: 61336-70-7
Synonyms: Amoxycillin trihydrate
Target:  

Bacterial Antibiotic

Forschungsgebiete:  

Infection Cancer

Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
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23
23 Cited Publications
Art. -Nr.: HY-131165
Target:  

Antibiotic Bacterial

Forschungsgebiete:  

Infection Cancer

Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
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22
22 Cited Publications
Art. -Nr.: HY-W010892
CAS. Nr.: 6533-68-2
Synonyms: Hyoscine hydrobromide trihydrate
Scopolamine (Hyoscine) hydrobromide trihydrate is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide trihydrate competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide trihydrate can induce cognitive and memory deficits in animals. Scopolamine hydrobromide trihydrate can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
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16
16 Cited Publications
Art. -Nr.: HY-B0639A
CAS. Nr.: 112901-68-5
Synonyms: WR2721 trihydrate
Forschungsgebiete:  

Cancer

Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action .
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13
13 Cited Publications
Art. -Nr.: HY-17015
CAS. Nr.: 1041434-82-5
Synonyms: RWJ 270201 trihydrate; BCX 1812 trihydrate
Peramivir trihydrate (RWJ-270201 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes .
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9
9 Cited Publications
Art. -Nr.: HY-B1381A
CAS. Nr.: 125110-14-7
Synonyms: FR-17027 trihydrate; FK-027 trihydrate; CL-284635 trihydrate
Target:  

Antibiotic Bacterial

Forschungsgebiete:  

Infection Inflammation/Immunology Cancer

Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
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6
6 Cited Publications
Art. -Nr.: HY-B0442B
CAS. Nr.: 330808-88-3
Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes [1]-[6].
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4
4 Cited Publications
Art. -Nr.: HY-14542
CAS. Nr.: 146939-27-7
Reinheit:  99.81%
Synonyms: CP-88059
Forschungsgebiete:  

Neurological Disease

Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist . Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM) .
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4
4 Cited Publications
Art. -Nr.: HY-Y1325H
CAS. Nr.: 6131-90-4
Sodium acetate trihydrate, meets analytical specification of Ph. Eur. BP USP FCC E262, ≤0.00002% Al is a carboxylic acid and short-chain fatty acid (SCFAs). Sodium acetate trihydrate activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Sodium acetate trihydrate exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Sodium acetate trihydrate regulates energy metabolism. Sodium acetate trihydrate has anticancer activity against gastric cancer. Sodium acetate trihydrate induces writhing reaction and ulcerative colitis. Sodium acetate trihydrate can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain .
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4
4 Cited Publications
Art. -Nr.: HY-W009722
CAS. Nr.: 20624-25-3
Synonyms: Ditiocarb sodium trihydrate
Sodium diethylcarbamodithioate (Ditiocarb sodium) trihydrate is a copper reagent. The reaction with Cu 2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer .
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