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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
tyrosinase and melanogenesis
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "tyrosinase and melanogenesis" in MCE Product Catalog:
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1 Cited Publications
Synonyms: Quercetin-3,3',4',7-tetramethylether
Cat. No.: HY-N2232
CAS No.: 66648-44-0
Synonyms: N-trans-Feruloyloctopamine
Cat. No.: HY-134046
CAS No.: 10391-08-9
Synonyms: Isodocarpin
Category:
Target:
Cat. No.: HY-N1098
CAS No.: 25739-41-7
Category:
Flavonoids Microorganisms Flavones Phenols Polyphenols Plants Other Families Extract Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-N10423
CAS No.: 18423-69-3
Synonyms: (-)-Cubebin
Target:
TSPO TRP Channel Microphthalmia Associated Transcription Factor (MITF) PKC PKA p38 MAPK PERK Interleukin Related
Research Areas:
FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases .
Cat. No.: HY-N3425
CAS No.: 1238116-48-7
Category:
Flavonoids Flavanols Other Diseases Phenols Polyphenols Plants Other Families Extract Disease Research Fields
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Cat. No.: HY-P0096
CAS No.: 137665-91-9
Target:
Research Areas:
Cat. No.: HY-N10016
CAS No.: 132741-56-1
Target:
Cat. No.: HY-143459
CAS No.: 2525175-90-8
Target:
Research Areas:
Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells .
Category:
Alkaloids Calycanthaceae Extract Chimonanthus nitens Oliv. Plants Disease Research Fields Cancer Alkaloid Dimers
Target:
Cat. No.: HY-117761
CAS No.: 1393371-39-5
Target:
Research Areas:
MHY908 is a potent dual agonist of PPARα and PPARγ . MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity .
Cat. No.: HY-W012092
CAS No.: 6178-44-5
Cat. No.: HY-158021
Target:
Research Areas:
Tyrosinase-IN-26 (compound 13) is a uncompetitive tyrosinase inhibitor with the an IC50 value of 68.86 µM. Tyrosinase-IN-26 can suppresses melanogenesis .
Cat. No.: HY-161969
Target:
Research Areas:
Tyrosinase-IN-34 (compound 5a) is a human tyrosinase inhibitor (IC50: 3.5 μM) with the potential to control melanogenesis and pigmentation .
Cat. No.: HY-157123
Purity: 99.33%
Target:
Research Areas:
Tyrosinase-IN-18 (compound 6) is a potent tyrosinase inhibitor. Tyrosinase-IN-18 inhibits melanogenesis in B16F10 mammalian cells. Tyrosinase-IN-18 has strong antioxidant activities against ROS, ABTS +, and DPPH radicals .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
