SUVN-507
SUVN-507 is a 5-HT6 receptor antagonist. SUVN-507 can reverse cognitive impairments and enhance excitatory neural transmission while weakening inhibitory neural transmission. SUVN-507 can be used for the research of neurological disease, such as Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 959395-84-7
- Formula: C22H27N3O2S
- Molecular Weight:397.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT6 Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
310 nM
Compound: 7a
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Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminometry
Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminometry
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[PMID: 21134749] |
Chemical Information
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CAS No. 959395-84-7
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Molecular Weight 397.53
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Formula C22H27N3O2S
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SMILES
CN1CCN(C2=CN(S(=O)(C3=CC=C(C(C)C)C=C3)=O)C4=C2C=CC=C4)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)