TOP1288
TOP1288 is a narrow spectrum kinase inhibitor for P38α, Src and Syk kinase, with IC50 of 116nM, 24nM and 659nM, respectively. TOP1288 inhibits inflammatory cytokine release from inflamed biopsies and myofibroblasts.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1630202-02-6
- Formel: C43H49N7O9S
- Molecular Weight:839.96
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-12067
R406
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HY-11108
R406 free base
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HY-13038
Fostamatinib Disodium
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HY-100867A
Mivavotinib monohydrochloride
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HY-12736A
GSK143 dihydrochloride
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HY-13038R
Fostamatinib Disodium (Standard)
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HY-100867
Mivavotinib
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HY-100867AR
Mivavotinib monohydrochloride (Standard)
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HY-12736
GSK143
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HY-145029
SYK/JAK-IN-1
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HY-120214
TAS05567
Biologische Aktivität
IC50: 24 nM (Src), 116 nM (P38α), 659 nM (Syk)
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 1630202-02-6
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Molecular Weight 839.96
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Formel C43H49N7O9S
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SMILES
O=C(NC1=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C1OC)NC2=CC=C(C3=C2C=CC=C3)OC4=NC(NC5=CC(C#C)=CC(C(NCCOCCOCCOC)=O)=C5)=NC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TOP1288 Related Classifications
HY-160930 Related Classifications
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