Garcinone E
Based on 1 Customer Validation
Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas.
For research use only. We do not sell to patients.
- Purity: 98.19%
- CAS No.: 112649-21-5
- Formula: C28H32O6
- Molecular Weight:464.55
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
15 μM
Compound: 5
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Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by Trypan blue exclusion test
Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by Trypan blue exclusion test
|
[PMID: 12932141] |
| MCF7 | IC50 |
1.5 μg/mL
Compound: 8
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Cytotoxicity against human MCF7 cells assessed as [3H]hypoxanthin incorporation after 24 to 72 hrs
Cytotoxicity against human MCF7 cells assessed as [3H]hypoxanthin incorporation after 24 to 72 hrs
|
[PMID: 19296616] |
Chemical Information
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CAS No. 112649-21-5
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Appearance Solid
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Molecular Weight 464.55
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Formula C28H32O6
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Color Light yellow to yellow
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SMILES
O=C1C2=C(OC3=C1C(O)=C(C/C=C(C)\C)C(O)=C3)C(C/C=C(C)\C)=C(O)C(O)=C2C/C=C(C)\C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)