Uniconazole-P 

Uniconazole-P is a potent competitive inhibitor of Arabidopsis CYP707A3 with an IC₅₀ of 68 nM and a K_i of 8.0 nM. Uniconazole-P inhibits ent-kaurene oxidase, blocking gibberellin biosynthesis via reduced ent-kaurene to ent-kaurenoic acid oxidation. Uniconazole-P inhibits plant growth^[1][2][3][4].

Uniconazole-P (5%; 0-40 days) increases endogenous Abscisic acid (ABA) levels, reduces Indolc-3-Acetic Acid (IAA) levels, and total Gibberellin (GA)s levels in Mandarin Fruitlets^[2].
Uniconazole-P (10-100 nM; 12 h) significantly inhibits elongation of Lemna minor root segments at concentrations of 10 nM and 100 nM, with 10 nM treatment reducing elongation to ~25% of control levels, and this inhibition is reversed by exogenous GA₃(HY-N1964)^[4].
Uniconazole-P (10 nM; 24 h) inhibits elongation of Lemna minor root epidermal cells but does not alter lateral cell expansion^[4].
Uniconazole-P (10 nM; 0-30 h) disrupts the transverse orientation of cortical microtubules in Lemna minor root epidermal cells after 12 h incubation, with near-complete loss of CMTs after 24 h incubation, and this disruption is reversed by exogenous GA₃^[4].
Uniconazole-P inhibits DWF4, blocking brassinosteroid biosynthesis via reduced campestanol to 6-deoxocathasterone oxidation^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

291.78

C₁₅H₁₈ClN₃O

83657-17-4

ClC(C=C1)=CC=C1/C=C(N2C=NC=N2)\[C@@H](O)C(C)(C)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Saito S, et al. A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis. Biosci Biotechnol Biochem. 2006;70(7):1731-1739.  [Content Brief]

  [2]. Kojima K, et al. Effects of Uniconazole-P on Abscission and Endogenous ABA, IAA, and GA-like Substances Levels of Satsuma Mandarin Fruitlet. Biosci Biotechnol Biochem. 1996;60(5):901-902.

  [3]. Jiang S, et al. Role of GA3, GA4 and uniconazole-P in controlling gravitropism and tension wood formation in Fraxinus mandshurica Rupr. var. japonica Maxim. seedlings. J Integr Plant Biol. 2008;50(1):19-28.

  [4]. Inada S, et al. Regulation of elongation growth by gibberellin in root segments of Lemna minor. Plant Cell Physiol. 2000;41(8):932-939.