RUC-1
RUC-1 (Compound 1) is an inhibitor for αIIbβ3 integrin. RUC-1 inhibits fibrin deposition and platelet aggregation in hybrid hαIIb/mβ3 receptors expressing mice. RUC-1 exhibits antithrombotic effect in hαIIb/mβ3 receptor expressing mice.
For research use only. We do not sell to patients.
- CAS No.: 796886-30-1
- Formula: C11H15N5OS
- Molecular Weight:265.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | IC50 |
4 μM
Compound: 1, RUC-1
|
Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
|
[PMID: 24461295] |
Chemical Information
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CAS No. 796886-30-1
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Molecular Weight 265.33
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Formula C11H15N5OS
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SMILES
O=C1C=C(N2CCNCC2)N=C3SC(CC)=NN13
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)