Vps34-IN-3
Vps34-IN-3 is a potent, selective, and orally bioavailable VPS34 kinase inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 2770104-92-0
- Formula: C14H20N4O2
- Molecular Weight:276.33
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| U2OS | IC50 |
200 nM
Compound: 5
|
Inhibition of autophagy in GFP-FYVE tagged human U2OS cells assessed as decrease in PI3P-mediated GFP-puncta formation by Hoechst 33258 staining based fluorescence microscopic analysis
Inhibition of autophagy in GFP-FYVE tagged human U2OS cells assessed as decrease in PI3P-mediated GFP-puncta formation by Hoechst 33258 staining based fluorescence microscopic analysis
|
[PMID: 34779204] |
Chemical Information
-
CAS No. 2770104-92-0
-
Molecular Weight 276.33
-
Formula C14H20N4O2
-
SMILES
C[C@H]1N(C2=NN([C@H](CCC3)[C@H]3NC4=O)C4=C2)CCOC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)