2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. VU0410425

VU0410425 is an mGlu1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an IC50 value of 140 nM. VU0410425 can be used for the research of central nervous system disorders.

For research use only. We do not sell to patients.

VU0410425 Chemical Structure

VU0410425 Chemical Structure

CAS No. : 1341167-72-3

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VU0410425 Related Antibodies

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Description

VU0410425 is an mGlu1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an IC50 value of 140 nM. VU0410425 can be used for the research of central nervous system disorders[1].
IC50 & Target

IC50: 140 nM (rat mGlu1)[1]
In Vitro

VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an IC50 value of 140 nM, but inactive for human mGlu1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VU0410425 Related Antibodies
Molecular Weight

369.80

Formula

C19H16ClN3O3
CAS No.
SMILES

O=C(C1=NC=CC=C1)NC2=CC=C(N3C(C4C(C)(C)C4C3=O)=O)C(Cl)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VU0410425 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VU04104251341167-72-3VU 0410425VU-0410425mGluRMetabotropic glutamate receptorsglutamatenegative allosteric modulatormGlu1central nervous system disorders.Inhibitorinhibitorinhibit

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