VU0652835
VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM.
For research use only. We do not sell to patients.
- CAS No.: 1848252-81-2
- Formula: C16H19N3O3S
- Molecular Weight:333.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
mGlu5 81 nM (IC50) |
Chemical Information
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CAS No. 1848252-81-2
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Molecular Weight 333.41
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Formula C16H19N3O3S
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SMILES
CC1=CC(O[C@@H]2C[C@@H](C)OC2)=CC(C(NC3=NC(C)=CS3)=O)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)