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Cat. No.: HY-129794

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YM-298198

YM-298198 is a potent mGlu1 receptor with an IC₅₀ of 24 nM. YM-298198 can be used in the study of neurological disease.

For research use only. We do not sell to patients.

CAS No.: 748758-45-4
Formula: C₁₈H₂₂N₄OS
Molecular Weight:342.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

YM-298198 Chemical Structure

CAS No.: 748758-45-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

YM-298198 is a potent mGlu1 receptor with an IC₅₀ of 24 nM. YM-298198 can be used in the study of neurological disease^[1].

All mGluR Isoforms :

Chemical Information

CAS No. 748758-45-4
Molecular Weight 342.46
Formula C₁₈H₂₂N₄OS
SMILES

O=C(C1=C(C)N2C3=CC(N)=CC=C3N=C2S1)N(C4CCCCC4)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fukunaga I, et al. Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br J Pharmacol. 2007 Jul;151(6):870-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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