1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. 1-Ethynylpyrene

1-Ethynylpyrene 

Cat. No.: HY-131452
Handling Instructions

1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively.

For research use only. We do not sell to patients.

1-Ethynylpyrene Chemical Structure

1-Ethynylpyrene Chemical Structure

CAS No. : 34993-56-1

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Description

1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].

In Vitro

1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

226.27

Formula

C₁₈H₁₀

CAS No.

34993-56-1

SMILES

C#CC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

1-EthynylpyreneCytochrome P450CYPscytochromesP4501A11A22B1Inhibitorinhibitorinhibit

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