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  3. 653-47

653-47 

Cat. No.: HY-134598
Handling Instructions

653-47, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 is also a very weak CREB inhibitor with IC50 of 26.3 μM.

For research use only. We do not sell to patients.

653-47 Chemical Structure

653-47 Chemical Structure

CAS No. : 1224678-75-4

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Description

653-47, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 is also a very weak CREB inhibitor with IC50 of 26.3 μM[1].

In Vitro

653-47 (5-10 μM) synergistically inhibits CREB-mediated gene transcription with 666-15[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

370.83

Formula

C₂₀H₁₉ClN₂O₃

CAS No.

1224678-75-4

SMILES

O=C(C1=C(OCCCN)C=C2C=CC=CC2=C1)NC3=CC=C(Cl)C=C3O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

653-47Epigenetic Reader DomainCREBtranscriptionfactorcancerspotentiateInhibitorinhibitorinhibit

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