BET-IN-2
BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.
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- CAS. Nr.: 2104688-91-5
- Formel: C23H29N3O
- Molecular Weight:363.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
BRD4 BD1 52 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MM1.S | IC50 |
0.016 μM
Compound: 54
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Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
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[PMID: 28586718] |
Chemical Information
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CAS. Nr. 2104688-91-5
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Molecular Weight 363.50
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Formel C23H29N3O
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SMILES
CC1=C([C@H](C)NC2=CC(N(C3CC3)[C@H](C)C(N4C)=O)=C4C=C2)C=CC(C)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
BET-IN-2 Related Classifications
HY-102044 Related Classifications
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