1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. CFMTI

CFMTI 

Cat. No.: HY-100402 Purity: >98.0%
Handling Instructions

CFMTI inhibits L-glutamate-induced intracellular Ca2+ mobilization in CHO cells expressing human and rat mGluR1a, with IC50s of 2.6 and 2.3 nM, respectively.

For research use only. We do not sell to patients.

CFMTI Chemical Structure

CFMTI Chemical Structure

CAS No. : 864864-17-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 73 In-stock
Estimated Time of Arrival: December 31
5 mg USD 95 In-stock
Estimated Time of Arrival: December 31
10 mg USD 135 In-stock
Estimated Time of Arrival: December 31
25 mg USD 270 In-stock
Estimated Time of Arrival: December 31
50 mg USD 490 In-stock
Estimated Time of Arrival: December 31
100 mg USD 930 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

CFMTI inhibits L-glutamate-induced intracellular Ca2+ mobilization in CHO cells expressing human and rat mGluR1a, with IC50s of 2.6 and 2.3 nM, respectively[1].

IC50 & Target[1]

Human mGluR1a

2.6 nM (IC50)

Rat mGluR1a

2.3 nM (IC50)

Molecular Weight

349.36

Formula

C₁₉H₁₆FN₅O

CAS No.

864864-17-5

SMILES

O=C1N(C2CC2)CC3=C1C=CC(C4=C(C)N(C5=CC=CN=C5F)N=N4)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.2 mg/mL (17.75 mM; Need warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8624 mL 14.3119 mL 28.6238 mL
5 mM 0.5725 mL 2.8624 mL 5.7248 mL
10 mM 0.2862 mL 1.4312 mL 2.8624 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

CFMTImGluRMetabotropic glutamate receptorsInhibitorinhibitorinhibit

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