Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
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Drug Metabolite Related Products (2022)
Related Products (2022)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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6-Acetamidohexanoic acid (Standard)
0 ImagesSynonyms: Acexamic acid (Standard); 6-Acetamidocaproic acid (Standard)6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) (Standard) is the analytical standard of 6-Acetamidohexanoic acid. This product is intended for research and analytical applications. 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer.
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2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine
0 ImagesCat. No.: HY-W720429CAS No.: 73477-63-12,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine is a metabolite in the biosynthesis pathway (purine metabolism process) of Riboflavin (HY-B0456).
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Fensulfothion sulfone
0 ImagesCat. No.: HY-133992CAS No.: 14255-72-2Fensulfothion sulfone is a metabolite of the organophosphorus insecticide fensulfothion.
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Captopril EP Impurity E (Standard)
0 ImagesCat. No.: HY-137772RCAS No.: 23500-15-4Captopril EP Impurity E (Standard) is the analytical standard of Captopril EP Impurity E. This product is intended for research and analytical applications. Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
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Diclofop
0 ImagesCat. No.: HY-121273CAS No.: 40843-25-2Synonyms: Dichlorfop acid; (±)-DiclofopDiclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367). Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum.
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4-(Sulfooxy)benzoic acid
0 Images4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids.
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5-O-Desmethyl donepezil
0 ImagesCat. No.: HY-133926CAS No.: 120013-57-2
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Allopurinol riboside (Standard)
0 ImagesCat. No.: HY-101397RCAS No.: 16220-07-8Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
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N-Nitrosoglyphosate
0 ImagesCat. No.: HY-W653737CAS No.: 56516-72-4N-Nitrosoglyphosate is the nitrosamine degradation product of glyphosate herbicidee.
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T-1095A
0 ImagesCat. No.: HY-125594CAS No.: 209746-56-5
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(±)19(20)-DiHDTE
0 ImagesCat. No.: HY-172833(±)19(20)-DiHDTE is a an oxidized lipid compound. (±)19(20)-DiHDTE is the product formed when docosapentaenoic acid (DPA) is oxidatively metabolized by cytochrome P450.
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Di-o-cresyl phosphate
0 ImagesDi-o-cresyl phosphate is a urinary metabolite of tri-o-cresyl phosphate (HY-W011086), o,o,m-tricresyl phosphate, and o,o,p-tricresyl phosphate, and serves as a biomarker for monitoring exposure to ortho-isomers of tricresyl phosphate. Di-o-cresyl phosphate is not a metabolite of mono-o-tricresyl phosphate. Di-o-cresyl phosphate can be used in studies related to delayed neuropathy (OPIDN).
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Oroxylin A-7-O-glucuronide (Standard)
0 ImagesCat. No.: HY-N2481RCAS No.: 36948-76-2Synonyms: Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities.
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Menthofuran-13C2
0 ImagesCat. No.: HY-N9484SCAS No.: 3028870-62-1Menthofuran-13C2 is the 13C-labeled Menthofuran, 84% (HY-N9484). Menthofuran, 84% is an orally active modulator of pulegone reductase with gastroprotective activity, and it is the metabolite of (R)-(+)-Pulegone. Menthofuran, 84% reduces the transcriptional level of pulegone reductase in immature peppermint leaves, increases the content of pulegone in peppermint essential oil, and regulates the biosynthesis of peppermint essential oil through a feedforward-like inhibition mechanism. Menthofuran, 84% decreases total gastric acidity, restores non-protein thiol levels, inhibits lipid peroxidation, and reduces myeloperoxidase activity, with its mechanism of action related to the NOS pathway and endogenous prostaglandins. Menthofuran, 84% can be used in studies related to gastric ulcers.
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Ginsenoside C-Y
0 ImagesCat. No.: HY-N9389CAS No.: 83480-65-3Synonyms: Ginsenoside YGinsenoside C-Y (Ginsenoside Y) is a metabolite of Ginsenoside Rb2 (HY-N0040). Ginsenoside C-Y exhibits anti-photoaging and anti-melanogenesis properties.
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3-O-Methyltolcapone (Standard)
0 ImagesCat. No.: HY-100642RCAS No.: 134612-80-9Synonyms: Ro 40-7591 (Standard)3-O-Methyltolcapone (Standard) (Ro 40-7591 (Standard)) is the analytical standard of 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.
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1α,25-Dihydroxyprevitamin D3
0 ImagesCat. No.: HY-131450CAS No.: 57102-09-71α,25-Dihydroxyprevitamin D3 is the precursor of Vitamin D3.
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2-Amino-2'-chloro-5-nitrobenzophenone
0 Images2-Amino-2'-chloro-5-nitrobenzophenone serves as a starting material for the synthesis of a psychoactive substance.
