Integrin
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Integrin Inhibitors
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Integrin Agonists
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Integrin Ligands
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Integrin Related Products (382)
Related Products (382)
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LFA-1-IN-2
0 ImagesCat. No.: HY-180939LFA-1-IN-2 (Compound 25) is a potent LFA-1 inhibitor with a Kd of 21.46 μM. LFA-1-IN-2 inhibits ICAM-1-mediated cell adhesion. LFA-1-IN-2 protects cells from inflammatory hyperosmotic stress. LFA-1-IN-2 improves dry eye disease.
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6-B345TTQ
0 ImagesCat. No.: HY-139043CAS No.: 297157-87-06-B345TTQ is an α4 integrin inhibitor that inhibits α4-Leupaxin interaction. 6-B345TTQ can be used in inflammation research.
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Cyclo(Ala-Arg-Gly-Asp-Mamb)
0 ImagesSynonyms: XJ735Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension research.
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Ventegatide
0 ImagesCat. No.: HY-P11669CAS No.: 478496-41-2Ventegatide is an integrin-binding peptide that can be used for the study of osteoarthritis.
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Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge: Cys1-Cys10)
0 ImagesCat. No.: HY-P4320CAS No.: 166184-23-2
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Xemilofiban
0 ImagesCat. No.: HY-10305CAS No.: 149820-74-6Xemilofiban is an orally active glycoprotein IIb/IIIa blocking agent. Xemilofiban inhibits platelet aggregation. Xemilofiban reduces the incidence of thrombosis.
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Risuteganib
0 ImagesCat. No.: HY-P1930CAS No.: 1307293-62-4Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide. Risuteganib is an anti-integrin that downregulates oxidative stress and restores homeostasis, and targets three integrin receptors that are implicated in dry age-related macular degeneration (AMD) in order to restore homeostasis in the retina.
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DSPE-PEG3400-cRGD
0 ImagesCat. No.: HY-172464ADSPE-PEG3400-cRGD is a PEG compound which composed of DSPE and an αvβ3 targeting peptide (cRGD). cRGD peptide can specifically bind to αvβ3 on the surface of many cancer cells and neovascular cells. DSPE-PEG3400-cRGD can be used for drug delivery.
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ML165
0 ImagesCat. No.: HY-120694CAS No.: 1355454-05-5Synonyms: RUC-2ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC50: 96 nM).
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Fuzapladib calcium
0 ImagesCat. No.: HY-19151CCAS No.: 141284-77-7Synonyms: IS-741 calciumFuzapladib calcium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib calcium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib calcium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site.
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MorHap
0 ImagesCat. No.: HY-157172MorHap is a heroin hapten. MorHap conjugated to tetanus toxoid (TT), palm-CV2, and to monophosphoryl lipid A (MPLA)-containing liposomes partially blocks heroin-induced analgesia and hyperlocomotion in mice. MorHap designed conjugates also significantly inhibits HIV-1 binding to α4β7 receptors. MorHap can be used in research to develop vaccines related to heroin addiction and HIV-1 infection.
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Irigenin (Standard)
0 ImagesIrigenin (Standard) is the analytical standard of Irigenin. This product is intended for research and analytical applications. Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells.
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RPR-109891
0 ImagesCat. No.: HY-107080CAS No.: 169512-56-5RPR-109891 is an orally active glycoprotein IIb/IIIa peptide antagonist. RPR-109891 can decrease platelet count and reduce platelet survival time. RPR-109891 can be used for the research of cardiovascular disease, such as myocardial infarction.
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ATL 1102 sodium scrambled negative control
0 ImagesCat. No.: HY-153481CATL 1102 sodium scrambled negative control is the sequence scrambled negative control of ATL 1102 sodium.
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Sulfobacin B
0 ImagesCat. No.: HY-N19251CAS No.: 170242-21-4Sulfobacin B is a competitive von Willebrand factor receptor GPIb/IX inhibitor with an IC50 of 2.2 μM. Sulfobacin B inhibits binding of von Willebrand factor to GPIb/IX in a competitive manner. Sulfobacin B can be used for the research of thrombosis.
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Isoxanthohumol (Standard)
0 ImagesIsoxanthohumol (Standard) is the analytical standard of Isoxanthohumol (HY-N2584A). This product is intended for research and analytical applications. Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases.
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Tirofiban hydrochloride monohydrate (Standard)
0 ImagesSynonyms: L700462 hydrochloride monohydrate (Standard); MK383 hydrochloride monohydrate (Standard)Tirofiban (hydrochloride monohydrate) (Standard) is the analytical standard of Tirofiban (hydrochloride monohydrate). This product is intended for research and analytical applications. Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
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Cyclo(RGDyK) (Standard)
0 ImagesCat. No.: HY-100563ARCAS No.: 217099-14-4Cyclo(RGDyK) (Standard) is the analytical standard of Cyclo(RGDyK) (HY-100563A). This product is intended for research and analytical applications. Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
