Folate Receptor (FR)
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Folate Receptor (FR) Related Products (23)
Related Products (23)
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EC-17 disodium salt
0 ImagesCat. No.: HY-13615ACAS No.: 910661-33-5EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively.
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DSPE-PEG2000-Folate
0 ImagesCat. No.: HY-W440888DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems[2].
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Folate-FITC
0 ImagesCat. No.: HY-13615CAS No.: 583037-91-6Synonyms: EC-17Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively.
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Torvutatug
0 ImagesSynonyms: AZD5335 Antibody; INT-019Torvutatug (AZD5335 Antibody) is a human IgG1 κ monoclonal antibody against FRα, with an IC50 value of 7.4 nM against hFRα. Torvutatug can serve as an ADC antibody for the synthesis of ADC, such as AZD5335. Torvutatug is applicable to ovarian cancer-related research.
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NVP-EVS459
0 ImagesNVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate. NVP-EVS459 labeled with 177Lu can be used for tumor diagnosis and research.
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Eliroptamig
0 ImagesCat. No.: HY-P992112CAS No.: 3064817-30-4Eliroptamig is a multispecific antibody targeting albumin, folate receptor α (FOLR1) and cluster of differentiation 3 (CD3). Eliroptamig extends its half-life by binding to albumin, while targeting FOLR1 on tumor cells and activating T cells to achieve precise tumor killing.
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Opugotamig olatansine
0 ImagesCat. No.: HY-185427Synonyms: IMGN-151Opugotamig olatansine (IMGN151) is a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC). Opugotamig olatansine comprises antibody Opugotamig (HY-P990935) and linker-payload NMS-P945 (HY-185569). Opugotamig olatansine binds to two independent epitopes of FRα and promotes antibody binding, internalization, and processing. Opugotamig olatansine can be used for the research of FRα-positive ovarian cancer.
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DBCO-PEG1000-FA
0 ImagesCat. No.: HY-W1123936BSynonyms: DBCO-PEG1000-FolateDBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications.
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Lazatatug
0 ImagesCat. No.: HY-P991695CAS No.: 3035565-36-4Lazatatug is an anti-FOLR1 IgEκ type humanized antibody with antineoplastic activity.
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CBP-1018
0 ImagesCBP-1018 is a PDC (peptide-drug conjugate) formed by conjugating Monomethyl auristatin E (HY-15162) to a dual-targeting ligand of FLOR1/PSMA (prostate-specific membrane antigen) via a linker (HY-78738). CBP-1018 binds to FLOR1 and prostate-specific membrane antigen (PSMA). CBP-1018 is applicable to the research of solid tumors and metastatic castration-resistant prostate cancer.
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DBCO-PEG3400-FA
0 ImagesCat. No.: HY-W1123936DSynonyms: DBCO-PEG3400-FolateDBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications.
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DBCO-PEG10000-FA
0 ImagesCat. No.: HY-W1123936HSynonyms: DBCO-PEG10000-FolateDBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications.
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Anti-FOLR2 Antibody
0 ImagesCat. No.: HY-P992520Anti-FOLR2 Antibody is a specific antibody targeting folate receptor β (FOLR2). Anti-FOLR2 Antibody effectively detects intracellular and extracellular FOLR2 expression in flow cytometry and confocal microscopy experiments, facilitating the precise detection and isolation of FOLR2+ macrophages in breast cancer. Anti-FOLR2 Antibody is also widely used in studies on the mechanisms, diagnosis and treatment of chronic lymphocytic leukemia (CLL).
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EC1454
0 ImagesCat. No.: HY-128937CAS No.: 1602487-15-9EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy.
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EC119
0 ImagesCat. No.: HY-P2631CAS No.: 742091-99-2EC119 consists of Pteroic acid-gGlu-Asp-Arg-Asp-Asp-Cys, which is the folate–peptide moiety found within both the EC140 and EC145 structures.
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EC216
0 ImagesCat. No.: HY-188043CAS No.: 926623-28-1Synonyms: Pte-Cys-ss-DAVLBHEC216 is a folate receptor (FR) targeted conjugate that competes for binding at the FR site, with a relative binding affinity of 0.046. EC216 is applicable to studies related to folate receptor-targeted delivery and vinca alkaloid cytotoxins.
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DBCO-PEG2000-FA
0 ImagesCat. No.: HY-W1123936CSynonyms: DBCO-PEG2000-FolateDBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications.
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Pteropterin monohydrate
0 ImagesCat. No.: HY-127118ACAS No.: 6164-84-7Synonyms: Pteroyltriglutamic monohydratePteropterin (Pteroyltriglutamic) monohydrate is an active form of folate. Pteropterin monohydrate shows inhibiting effect on tumor growth and has broad anticancer activity.
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Etarfolatide
0 ImagesCat. No.: HY-13616CAS No.: 479578-27-3Synonyms: EC 20Etarfolatide (EC 20) is a valuable noninvasive imaging agent. Etarfolatide identifies folate receptor expression. Etarfolatide can be used in research on ovarian cancer and disease diagnosis after being radiolabeled.
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KHK2805
0 ImagesCat. No.: HY-P992004Synonyms: RA15-7, HuRA15-7AccKHK2805 (RA15-7) is a humanized antibody against folate receptor α (FOLR1), with a Kd of 0.647 nM for human FOLR1. KHK2805 binds to a unique epitope of FOLR1 and mediates antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against FOLR1-expressing cells. KHK2805 exhibits cytotoxicity against both ovarian cancer cells and Platinum (HY-W096169D)-resistant ovarian cancer cells. KHK2805 can be used for the research of tumors such as ovarian cancer.
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