1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. HSP
  3. AMP-PCP

AMP-PCP 

Cat. No.: HY-106723
Handling Instructions

AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90.

For research use only. We do not sell to patients.

AMP-PCP Chemical Structure

AMP-PCP Chemical Structure

CAS No. : 3469-78-1

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other In-stock Forms of AMP-PCP:

Other Forms of AMP-PCP:

Top Publications Citing Use of Products

View All HSP Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90[1].

IC50 & Target[1]

HSP90

3.8 μM (Kd)

In Vitro

AMP-PCP binding favors the formation of the active homodimer of Hsp90 by enhancing the slow-motion featured conformational exchanges of those residues (A117-A141) within the lid segment (A111-G135) and around region. In total, 170 non-proline residues are identified for the triple-labeled Hsp90 bound with AMP-PCP[1].

Molecular Weight

505.21

Formula

C₁₁H₁₈N₅O₁₂P₃

CAS No.

3469-78-1

SMILES

O[[email protected]]1[[email protected]@H](O[[email protected]](COP(OP(CP(O)(O)=O)(O)=O)(O)=O)[[email protected]]1O)N2C3=C(C(N)=NC=N3)N=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

AMP-PCPHSPHeat shock proteinsATPhomodimerHsp90residuesconformationalN-terminalATPaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
AMP-PCP
Cat. No.:
HY-106723
Quantity:
MCE Japan Authorized Agent: